"Tissue Distribution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Accumulation of a drug or chemical substance in various organs (including those not relevant to its pharmacologic or therapeutic action). This distribution depends on the blood flow or perfusion rate of the organ, the ability of the drug to penetrate organ membranes, tissue specificity, protein binding. The distribution is usually expressed as tissue to plasma ratios.
Descriptor ID |
D014018
|
MeSH Number(s) |
G03.787.917 G07.690.725.949
|
Concept/Terms |
Tissue Distribution- Tissue Distribution
- Distribution, Tissue
- Distributions, Tissue
- Tissue Distributions
|
Below are MeSH descriptors whose meaning is more general than "Tissue Distribution".
Below are MeSH descriptors whose meaning is more specific than "Tissue Distribution".
This graph shows the total number of publications written about "Tissue Distribution" by people in this website by year, and whether "Tissue Distribution" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 13 | 13 |
1995 | 0 | 18 | 18 |
1996 | 0 | 14 | 14 |
1997 | 0 | 19 | 19 |
1998 | 0 | 12 | 12 |
1999 | 0 | 33 | 33 |
2000 | 0 | 34 | 34 |
2001 | 0 | 27 | 27 |
2002 | 0 | 26 | 26 |
2003 | 0 | 34 | 34 |
2004 | 0 | 26 | 26 |
2005 | 0 | 34 | 34 |
2006 | 0 | 29 | 29 |
2007 | 0 | 16 | 16 |
2008 | 0 | 15 | 15 |
2009 | 0 | 12 | 12 |
2010 | 0 | 17 | 17 |
2011 | 0 | 15 | 15 |
2012 | 0 | 28 | 28 |
2013 | 0 | 19 | 19 |
2014 | 0 | 16 | 16 |
2015 | 0 | 16 | 16 |
2016 | 0 | 3 | 3 |
2017 | 0 | 11 | 11 |
2018 | 0 | 7 | 7 |
2019 | 0 | 22 | 22 |
2020 | 0 | 10 | 10 |
2021 | 0 | 7 | 7 |
2022 | 0 | 2 | 2 |
2023 | 0 | 1 | 1 |
2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Tissue Distribution" by people in Profiles.
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Somatostatin Receptor Subtype-2 Targeting System for Specific Delivery of Temozolomide. J Med Chem. 2024 Feb 22; 67(4):2425-2437.
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SPIONs: Superparamagnetic iron oxide-based nanoparticles for the delivery of microRNAi-therapeutics in cancer. Biomed Microdevices. 2024 Feb 07; 26(1):16.
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Development of a Novel Tool To Demystify Drug Distribution at Tissue-Blood Barriers. Chembiochem. 2023 07 03; 24(13):e202200804.
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A nanoengineered topical transmucosal cisplatin delivery system induces anti-tumor response in animal models and patients with oral cancer. Nat Commun. 2022 08 17; 13(1):4829.
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CD44 receptor targeted nanoparticles augment immunity against tuberculosis in mice. J Control Release. 2022 09; 349:796-811.
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Factors Influencing Luciferase-Based Bioluminescent Imaging in Preclinical Models of Brain Tumor. Drug Metab Dispos. 2022 03; 50(3):277-286.
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A deep-learning-based prediction model for the biodistribution of 90 Y microspheres in liver radioembolization. Med Phys. 2021 Nov; 48(11):7427-7438.
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Recent advances in intravital microscopy for preclinical research. Curr Opin Chem Biol. 2021 08; 63:200-208.
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How to stop using gadolinium chelates for magnetic resonance imaging: clinical-translational experiences with ferumoxytol. Pediatr Radiol. 2022 Feb; 52(2):354-366.
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Assessment of drug transporters involved in the urinary secretion of [99mTc]dimercaptosuccinic acid. Nucl Med Biol. 2021 Mar-Apr; 94-95:92-97.