"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
Descriptor ID |
D013569
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MeSH Number(s) |
A08.850 A11.284.149.165.420.780
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 5 | 1 | 6 |
1995 | 2 | 0 | 2 |
1996 | 2 | 2 | 4 |
1997 | 2 | 1 | 3 |
1998 | 0 | 2 | 2 |
1999 | 3 | 6 | 9 |
2000 | 3 | 2 | 5 |
2001 | 3 | 3 | 6 |
2002 | 2 | 5 | 7 |
2003 | 8 | 3 | 11 |
2004 | 10 | 8 | 18 |
2005 | 8 | 10 | 18 |
2006 | 7 | 4 | 11 |
2007 | 11 | 4 | 15 |
2008 | 9 | 9 | 18 |
2009 | 12 | 3 | 15 |
2010 | 10 | 5 | 15 |
2011 | 10 | 4 | 14 |
2012 | 9 | 6 | 15 |
2013 | 10 | 6 | 16 |
2014 | 13 | 5 | 18 |
2015 | 7 | 7 | 14 |
2016 | 8 | 5 | 13 |
2017 | 8 | 1 | 9 |
2018 | 8 | 7 | 15 |
2019 | 4 | 5 | 9 |
2020 | 11 | 3 | 14 |
2021 | 8 | 6 | 14 |
2022 | 2 | 10 | 12 |
2023 | 3 | 6 | 9 |
2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Retrograde endocannabinoid signaling at inhibitory synapses in vivo. Science. 2024 Mar; 383(6686):967-970.
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Clinical and functional consequences of GRIA variants in patients with neurological diseases. Cell Mol Life Sci. 2023 Nov 03; 80(11):345.
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Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments. Nat Commun. 2023 10 26; 14(1):6797.
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Regulation of Syntaxin3B-Mediated Membrane Fusion by T14, Munc18, and Complexin. Biomolecules. 2023 09 28; 13(10).
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Presynapses contain distinct actin nanostructures. J Cell Biol. 2023 10 02; 222(10).
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Remote neuronal activity drives glioma progression through SEMA4F. Nature. 2023 Jul; 619(7971):844-850.
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NMDA Receptors at Primary Afferent-Excitatory Neuron Synapses Differentially Sustain Chemotherapy- and Nerve Trauma-Induced Chronic Pain. J Neurosci. 2023 05 24; 43(21):3933-3948.
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Inhibitory input directs astrocyte morphogenesis through glial GABABR. Nature. 2023 May; 617(7960):369-376.
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Droplet-based transcriptome profiling of individual synapses. Nat Biotechnol. 2023 09; 41(9):1332-1344.
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Spectrin-beta 2 facilitates the selective accumulation of GABAA receptors at somatodendritic synapses. Commun Biol. 2023 01 05; 6(1):11.