Proto-Oncogene Proteins c-myc
"Proto-Oncogene Proteins c-myc" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Basic helix-loop-helix transcription factors encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis.
Descriptor ID |
D016271
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MeSH Number(s) |
D12.776.260.103.813 D12.776.624.664.700.189 D12.776.660.765 D12.776.930.125.813
|
Concept/Terms |
Proto-Oncogene Proteins c-myc- Proto-Oncogene Proteins c-myc
- Proto Oncogene Proteins c myc
- myc Proto-Oncogene Product p62
- myc Proto Oncogene Product p62
- Proto-Oncogene Proteins myc
- Proteins myc, Proto-Oncogene
- Proto Oncogene Proteins myc
- myc, Proto-Oncogene Proteins
- p62 c-myc
- p62 c myc
- p62(c-myc)
- Proto-Oncogene Products c-myc
- Proto Oncogene Products c myc
- c-myc Proteins
- c myc Proteins
- myc Proto-Oncogene Proteins
- Proto-Oncogene Proteins, myc
- myc Proto Oncogene Proteins
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-myc".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-myc".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-myc" by people in this website by year, and whether "Proto-Oncogene Proteins c-myc" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 2 | 0 | 2 |
1995 | 5 | 2 | 7 |
1996 | 2 | 0 | 2 |
1997 | 2 | 2 | 4 |
1998 | 3 | 3 | 6 |
1999 | 1 | 1 | 2 |
2000 | 6 | 6 | 12 |
2001 | 2 | 3 | 5 |
2002 | 2 | 3 | 5 |
2003 | 3 | 8 | 11 |
2004 | 5 | 2 | 7 |
2005 | 5 | 4 | 9 |
2006 | 9 | 7 | 16 |
2007 | 6 | 2 | 8 |
2008 | 4 | 4 | 8 |
2009 | 2 | 7 | 9 |
2010 | 5 | 9 | 14 |
2011 | 11 | 5 | 16 |
2012 | 11 | 12 | 23 |
2013 | 7 | 9 | 16 |
2014 | 6 | 5 | 11 |
2015 | 17 | 12 | 29 |
2016 | 17 | 17 | 34 |
2017 | 8 | 8 | 16 |
2018 | 15 | 5 | 20 |
2019 | 5 | 3 | 8 |
2020 | 12 | 4 | 16 |
2021 | 9 | 10 | 19 |
2022 | 5 | 5 | 10 |
2023 | 0 | 9 | 9 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-myc" by people in Profiles.
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The synergy of the XPO1 inhibitors combined with the BET inhibitor INCB057643 in high-grade B-cell lymphoma via downregulation of MYC expression. Sci Rep. 2023 10 29; 13(1):18554.
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The Clinicopathologic Features and Molecular Signatures of Blastoid High-Grade B Cell Lymphoma, Not Otherwise Specified. Mod Pathol. 2023 Dec; 36(12):100349.
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MYC is a regulator of androgen receptor inhibition-induced metabolic requirements in prostate cancer. Cell Rep. 2023 10 31; 42(10):113221.
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MYC Deregulation and PTEN Loss Model Tumor and Stromal Heterogeneity of Aggressive Triple-Negative Breast Cancer. Nat Commun. 2023 09 13; 14(1):5665.
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Reprogramming tumour-associated macrophages to outcompete cancer cells. Nature. 2023 Jul; 619(7970):616-623.
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Clinical relevance of MYC/BCL2 expression and cell of origin in patients with diffuse large b-cell lymphoma treated with autologous transplant. Bone Marrow Transplant. 2023 09; 58(9):1000-1007.
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Patterns of Oncogene Coexpression at Single-Cell Resolution Influence Survival in Lymphoma. Cancer Discov. 2023 05 04; 13(5):1144-1163.
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Metabolism-based targeting of MYC via MPC-SOD2 axis-mediated oxidation promotes cellular differentiation in group 3 medulloblastoma. Nat Commun. 2023 05 02; 14(1):2502.
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ABL kinases regulate the stabilization of HIF-1a and MYC through?CPSF1. Proc Natl Acad Sci U S A. 2023 04 18; 120(16):e2210418120.
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Clinical impact of 5'MYC or 3'MYC gain/loss detected by FISH in patients with aggressive B-cell lymphomas. Cancer Genet. 2023 04; 272-273:1-8.