"CpG Islands" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Areas of increased density of the dinucleotide sequence cytosine--phosphate diester--guanine. They form stretches of DNA several hundred to several thousand base pairs long. In humans there are about 45,000 CpG islands, mostly found at the 5' ends of genes. They are unmethylated except for those on the inactive X chromosome and some associated with imprinted genes.
| Descriptor ID |
D018899
|
| MeSH Number(s) |
G02.111.570.080.380.160 G05.360.080.380.160 G05.360.340.024.159
|
| Concept/Terms |
CpG Islands- CpG Islands
- CpG Island
- Island, CpG
- Islands, CpG
- CpG-Rich Islands
- CpG Rich Islands
- CpG-Rich Island
- Island, CpG-Rich
- Islands, CpG-Rich
CpG Clusters- CpG Clusters
- Cluster, CpG
- Clusters, CpG
- CpG Cluster
|
Below are MeSH descriptors whose meaning is more general than "CpG Islands".
Below are MeSH descriptors whose meaning is more specific than "CpG Islands".
This graph shows the total number of publications written about "CpG Islands" by people in this website by year, and whether "CpG Islands" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 2 | 3 |
| 2001 | 3 | 8 | 11 |
| 2002 | 4 | 5 | 9 |
| 2003 | 4 | 9 | 13 |
| 2004 | 4 | 8 | 12 |
| 2005 | 5 | 6 | 11 |
| 2006 | 3 | 10 | 13 |
| 2007 | 5 | 13 | 18 |
| 2008 | 4 | 11 | 15 |
| 2009 | 7 | 7 | 14 |
| 2010 | 7 | 8 | 15 |
| 2011 | 1 | 19 | 20 |
| 2012 | 3 | 10 | 13 |
| 2013 | 2 | 24 | 26 |
| 2014 | 3 | 23 | 26 |
| 2015 | 3 | 11 | 14 |
| 2016 | 2 | 15 | 17 |
| 2017 | 5 | 9 | 14 |
| 2018 | 0 | 13 | 13 |
| 2019 | 3 | 13 | 16 |
| 2020 | 3 | 9 | 12 |
| 2021 | 0 | 8 | 8 |
| 2022 | 0 | 4 | 4 |
| 2023 | 0 | 6 | 6 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "CpG Islands" by people in Profiles.
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Comprehensive evaluation of smoking exposures and their interactions on DNA methylation. EBioMedicine. 2024 Feb; 100:104956.
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Identification of genetically predicted DNA methylation markers associated with non-small cell lung cancer risk among 34,964 cases and 448,579 controls. Cancer. 2024 03 15; 130(6):913-926.
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Comparative and integrative analysis of transcriptomic and epigenomic-wide DNA methylation changes in African American prostate cancer. Epigenetics. 2023 12; 18(1):2180585.
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Epigenomic signature of major congenital heart defects in newborns with Down syndrome. Hum Genomics. 2023 Oct 06; 17(1):92.
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The Role of FAS Receptor Methylation in Osteosarcoma Metastasis. Int J Mol Sci. 2023 Jul 29; 24(15).
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Methylation of nonessential genes in cutaneous melanoma - Rule Out hypothesis. Melanoma Res. 2023 06 01; 33(3):163-172.
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Systemic interindividual epigenetic variation in humans is associated with transposable elements and under strong genetic control. Genome Biol. 2023 01 12; 24(1):2.
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Functional correlation of genome-wide DNA methylation profiles in genetic neurodevelopmental disorders. Hum Mutat. 2022 11; 43(11):1609-1628.
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Pulmonary Function and Blood DNA Methylation: A Multiancestry Epigenome-Wide Association Meta-analysis. Am J Respir Crit Care Med. 2022 08 01; 206(3):321-336.
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DNA methylation signature of chronic low-grade inflammation and its role in cardio-respiratory diseases. Nat Commun. 2022 05 03; 13(1):2408.