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DE PEI LI

TitleAssociate Professor
InstitutionMD Anderson
DepartmentCritical Care
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Li DP, Zhou JJ, Zhang J, Pan HL. CaMKII Regulates Synaptic NMDA Receptor Activity of Hypothalamic Presympathetic Neurons and Sympathetic Outflow in Hypertension. J Neurosci. 2017 11 01; 37(44):10690-10699. PMID: 28972129; PMCID: PMC5666588.
      Citations: 14     Fields:    Translation:AnimalsCells
    2. Li L, Li DP, Chen SR, Chen J, Hu H, Pan HL. Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition. Mol Pharmacol. 2014 Dec; 86(6):760-72. PMID: 25267719; PMCID: PMC4244593.
      Citations: 10     Fields:    Translation:HumansCells
    3. Qi Y, Wang J, Bomben VC, Li DP, Chen SR, Sun H, Xi Y, Reed JG, Cheng J, Pan HL, Noebels JL, Yeh ET. Hyper-SUMOylation of the Kv7 potassium channel diminishes the M-current leading to seizures and sudden death. Neuron. 2014 Sep 03; 83(5):1159-71. PMID: 25189211; PMCID: PMC4877174.
      Citations: 48     Fields:    Translation:AnimalsCells
    4. Pachuau J, Li DP, Chen SR, Lee HA, Pan HL. Protein kinase CK2 contributes to diminished small conductance Ca2+-activated K+ channel activity of hypothalamic pre-sympathetic neurons in hypertension. J Neurochem. 2014 Sep; 130(5):657-67. PMID: 24806793; PMCID: PMC4141038.
      Citations: 12     Fields:    Translation:AnimalsCells
    5. Li DP, Chen SR. Nitric oxide stimulates glutamatergic synaptic inputs to baroreceptor neurons through potentiation of Cav2.2-mediated Ca(2+) currents. Neurosci Lett. 2014 May 01; 567:57-62. PMID: 24686191; PMCID: PMC4978222.
      Citations: 2     Fields:    Translation:AnimalsCells
    6. Li DP, Zhu LH, Pachuau J, Lee HA, Pan HL. mGluR5 Upregulation increases excitability of hypothalamic presympathetic neurons through NMDA receptor trafficking in spontaneously hypertensive rats. J Neurosci. 2014 Mar 19; 34(12):4309-17. PMID: 24647951; PMCID: PMC3960469.
      Citations: 24     Fields:    Translation:AnimalsCells
    7. Xiong W, Chen SR, He L, Cheng K, Zhao YL, Chen H, Li DP, Homanics GE, Peever J, Rice KC, Wu LG, Pan HL, Zhang L. Presynaptic glycine receptors as a potential therapeutic target for hyperekplexia disease. Nat Neurosci. 2014 Feb; 17(2):232-9. PMID: 24390226; PMCID: PMC4019963.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    8. Shi X, Zhou F, Li X, Chang B, Li D, Wang Y, Tong Q, Xu Y, Fukuda M, Zhao JJ, Li D, Burrin DG, Chan L, Guan X. Central GLP-2 enhances hepatic insulin sensitivity via activating PI3K signaling in POMC neurons. Cell Metab. 2013 Jul 02; 18(1):86-98. PMID: 23823479; PMCID: PMC3752162.
      Citations: 37     Fields:    Translation:AnimalsCells
    9. Ye ZY, Li DP, Pan HL. Regulation of Hypothalamic Presympathetic Neurons and Sympathetic Outflow by Group II Metabotropic Glutamate Receptors in Spontaneously Hypertensive Rats. Hypertension. 2013 Aug; 62(2):255-62. PMID: 23716583; PMCID: PMC3734791.
      Citations: 13     Fields:    Translation:Animals
    10. Guo YX, Li DP, Chen SR, Pan HL. Distinct intrinsic and synaptic properties of pre-sympathetic and pre-parasympathetic output neurons in Barrington's nucleus. J Neurochem. 2013 Aug; 126(3):338-48. PMID: 23647148; PMCID: PMC3716857.
      Citations: 6     Fields:    Translation:AnimalsCells
    11. Zhou JJ, Wei Y, Zhang L, Zhang J, Guo LY, Gao C, Li DP, Zhang Y. Chronic intermittent hypobaric hypoxia prevents cardiac dysfunction through enhancing antioxidation in fructose-fed rats. Can J Physiol Pharmacol. 2013 May; 91(5):332-7. PMID: 23656204.
      Citations: 10     Fields:    Translation:Animals
    12. Cui F, Gao L, Yuan F, Dong ZF, Zhou ZN, Kline DD, Zhang Y, Li DP. Hypobaric intermittent hypoxia attenuates hypoxia-induced depressor response. PLoS One. 2012; 7(7):e41656. PMID: 22848558; PMCID: PMC3407201.
      Citations: 1     Fields:    Translation:Animals
    13. Shi X, Li X, Chang B, Wang Y, Li D, Chan L, Guan X. GLP-2 receptor in POMC neurons suppresses feeding behavior and gastric motility. Am J Physiol Endocrinol Metab. 2012 Oct 01; 303(7):E853-64. PMID: 22829581; PMCID: PMC3469617.
      Citations: 20     Fields:    Translation:AnimalsCells
    14. Ye ZY, Li DP, Byun HS, Li L, Pan HL. NKCC1 upregulation disrupts chloride homeostasis in the hypothalamus and increases neuronal activity-sympathetic drive in hypertension. J Neurosci. 2012 Jun 20; 32(25):8560-8. PMID: 22723696; PMCID: PMC3390258.
      Citations: 32     Fields:    Translation:AnimalsCells
    15. Ye ZY, Li L, Li DP, Pan HL. Casein kinase 2-mediated synaptic GluN2A up-regulation increases N-methyl-D-aspartate receptor activity and excitability of hypothalamic neurons in hypertension. J Biol Chem. 2012 May 18; 287(21):17438-17446. PMID: 22474321; PMCID: PMC3366779.
      Citations: 20     Fields:    Translation:AnimalsCells
    16. Li DP, Byan HS, Pan HL. Switch to glutamate receptor 2-lacking AMPA receptors increases neuronal excitability in hypothalamus and sympathetic drive in hypertension. J Neurosci. 2012 Jan 04; 32(1):372-80. PMID: 22219297; PMCID: PMC3566790.
      Citations: 31     Fields:    Translation:AnimalsCells
    17. Li Q, Ma HJ, Song SL, Shi M, Ma HJ, Li DP, Zhang Y. Effects of anandamide on potassium channels in rat ventricular myocytes: a suppression of I(to) and augmentation of K(ATP) channels. Am J Physiol Cell Physiol. 2012 Mar 15; 302(6):C924-30. PMID: 22173869.
      Citations: 6     Fields:    Translation:AnimalsCells
    18. Ye ZY, Li DP, Li L, Pan HL. Protein kinase CK2 increases glutamatergic input in the hypothalamus and sympathetic vasomotor tone in hypertension. J Neurosci. 2011 Jun 01; 31(22):8271-9. PMID: 21632948; PMCID: PMC3123887.
      Citations: 24     Fields:    Translation:Animals
    19. Ye ZY, Li DP. Activation of the melanocortin-4 receptor causes enhanced excitation in presympathetic paraventricular neurons in obese Zucker rats. Regul Pept. 2011 Jan 17; 166(1-3):112-20. PMID: 20937332.
      Citations: 13     Fields:    Translation:AnimalsCells
    20. Li DP, Pan HL. Increased group I metabotropic glutamate receptor activity in paraventricular nucleus supports elevated sympathetic vasomotor tone in hypertension. Am J Physiol Regul Integr Comp Physiol. 2010 Aug; 299(2):R552-61. PMID: 20519363; PMCID: PMC2928616.
      Citations: 15     Fields:    Translation:AnimalsCells
    21. Li DP, Chen SR, Pan HL. Adenosine inhibits paraventricular pre-sympathetic neurons through ATP-dependent potassium channels. J Neurochem. 2010 Apr; 113(2):530-42. PMID: 20096091.
      Citations: 14     Fields:    Translation:AnimalsCells
    22. Li DP, Pan HL. Role of GABAB receptors in autonomic control of systemic blood pressure. Adv Pharmacol. 2010; 58:257-86. PMID: 20655486.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    23. Wu ZZ, Li DP, Chen SR, Pan HL. Aminopyridines potentiate synaptic and neuromuscular transmission by targeting the voltage-activated calcium channel beta subunit. J Biol Chem. 2009 Dec 25; 284(52):36453-36461. PMID: 19850918; PMCID: PMC2794761.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    24. Sun H, Li DP, Chen SR, Hittelman WN, Pan HL. Sensing of blood pressure increase by transient receptor potential vanilloid 1 receptors on baroreceptors. J Pharmacol Exp Ther. 2009 Dec; 331(3):851-9. PMID: 19726694; PMCID: PMC2784714.
      Citations: 37     Fields:    Translation:AnimalsCells
    25. Li DP, Yang Q, Pan HM, Pan HL. Plasticity of pre- and postsynaptic GABAB receptor function in the paraventricular nucleus in spontaneously hypertensive rats. Am J Physiol Heart Circ Physiol. 2008 Aug; 295(2):H807-15. PMID: 18567709; PMCID: PMC2519208.
      Citations: 17     Fields:    Translation:AnimalsCells
    26. Li DP, Yang Q, Pan HM, Pan HL. Pre- and postsynaptic plasticity underlying augmented glutamatergic inputs to hypothalamic presympathetic neurons in spontaneously hypertensive rats. J Physiol. 2008 Mar 15; 586(6):1637-47. PMID: 18238817; PMCID: PMC2375700.
      Citations: 55     Fields:    Translation:AnimalsCells
    27. Xing J, Li DP, Li J. Role of GABA receptors in nitric oxide inhibition of dorsolateral periaqueductal gray neurons. Neuropharmacology. 2008 Mar; 54(4):734-44. PMID: 18222497; PMCID: PMC2955627.
      Citations: 7     Fields:    Translation:AnimalsCells
    28. Pan HL, Wu ZZ, Zhou HY, Chen SR, Zhang HM, Li DP. Modulation of pain transmission by G-protein-coupled receptors. Pharmacol Ther. 2008 Jan; 117(1):141-61. PMID: 17959251; PMCID: PMC2965406.
      Citations: 71     Fields:    Translation:HumansAnimalsCells
    29. Yang Q, Chen SR, Li DP, Pan HL. Kv1.1/1.2 channels are downstream effectors of nitric oxide on synaptic GABA release to preautonomic neurons in the paraventricular nucleus. Neuroscience. 2007 Oct 26; 149(2):315-27. PMID: 17869444.
      Citations: 16     Fields:    Translation:AnimalsCells
    30. Li DP, Yang Q. Membrane and synaptic properties of nucleus tractus solitarius neurons projecting to the caudal ventrolateral medulla. Auton Neurosci. 2007 Oct 30; 136(1-2):69-81. PMID: 17537680.
      Citations: 3     Fields:    Translation:AnimalsCells
    31. Li DP, Pan HL. Glutamatergic inputs in the hypothalamic paraventricular nucleus maintain sympathetic vasomotor tone in hypertension. Hypertension. 2007 Apr; 49(4):916-25. PMID: 17309953.
      Citations: 67     Fields:    Translation:Animals
    32. Li DP, Pan HL. Role of gamma-aminobutyric acid (GABA)A and GABAB receptors in paraventricular nucleus in control of sympathetic vasomotor tone in hypertension. J Pharmacol Exp Ther. 2007 Feb; 320(2):615-26. PMID: 17071818.
      Citations: 48     Fields:    Translation:Animals
    33. Zahner MR, Li DP, Pan HL. Benzodiazepine inhibits hypothalamic presympathetic neurons by potentiation of GABAergic synaptic input. Neuropharmacology. 2007 Feb; 52(2):467-75. PMID: 17045312.
      Citations: 8     Fields:    Translation:AnimalsCells
    34. Wang XL, Zhang HM, Li DP, Chen SR, Pan HL. Dynamic regulation of glycinergic input to spinal dorsal horn neurones by muscarinic receptor subtypes in rats. J Physiol. 2006 Mar 01; 571(Pt 2):403-13. PMID: 16410279; PMCID: PMC1796800.
      Citations: 15     Fields:    Translation:AnimalsCells
    35. Chen Q, Li DP, Pan HL. Presynaptic alpha1 adrenergic receptors differentially regulate synaptic glutamate and GABA release to hypothalamic presympathetic neurons. J Pharmacol Exp Ther. 2006 Feb; 316(2):733-42. PMID: 16249372.
      Citations: 17     Fields:    Translation:AnimalsCells
    36. Li DP, Pan HL. Plasticity of GABAergic control of hypothalamic presympathetic neurons in hypertension. Am J Physiol Heart Circ Physiol. 2006 Mar; 290(3):H1110-9. PMID: 16243912.
      Citations: 50     Fields:    Translation:Animals
    37. Li DP, Pan HL. Angiotensin II attenuates synaptic GABA release and excites paraventricular-rostral ventrolateral medulla output neurons. J Pharmacol Exp Ther. 2005 Jun; 313(3):1035-45. PMID: 15681656.
      Citations: 42     Fields:    Translation:AnimalsCells
    38. Zhang HM, Li DP, Chen SR, Pan HL. M2, M3, and M4 receptor subtypes contribute to muscarinic potentiation of GABAergic inputs to spinal dorsal horn neurons. J Pharmacol Exp Ther. 2005 May; 313(2):697-704. PMID: 15640398.
      Citations: 19     Fields:    Translation:AnimalsCells
    39. Li DP, Atnip LM, Chen SR, Pan HL. Regulation of synaptic inputs to paraventricular-spinal output neurons by alpha2 adrenergic receptors. J Neurophysiol. 2005 Jan; 93(1):393-402. PMID: 15356178.
      Citations: 16     Fields:    Translation:AnimalsCells
    40. Li DP, Chen SR, Pan HL. VR1 receptor activation induces glutamate release and postsynaptic firing in the paraventricular nucleus. J Neurophysiol. 2004 Sep; 92(3):1807-16. PMID: 15115794.
      Citations: 42     Fields:    Translation:Animals
    41. Pan YZ, Li DP, Chen SR, Pan HL. Activation of mu-opioid receptors excites a population of locus coeruleus-spinal neurons through presynaptic disinhibition. Brain Res. 2004 Jan 30; 997(1):67-78. PMID: 14715151.
      Citations: 11     Fields:    Translation:AnimalsCells
    42. Finnegan TF, Li DP, Chen SR, Pan HL. Activation of mu-opioid receptors inhibits synaptic inputs to spinally projecting rostral ventromedial medulla neurons. J Pharmacol Exp Ther. 2004 May; 309(2):476-83. PMID: 14724227.
      Citations: 10     Fields:    Translation:AnimalsCells
    43. Li DP, Chen SR, Finnegan TF, Pan HL. Signalling pathway of nitric oxide in synaptic GABA release in the rat paraventricular nucleus. J Physiol. 2004 Jan 01; 554(Pt 1):100-10. PMID: 14678495; PMCID: PMC1664752.
      Citations: 35     Fields:    Translation:AnimalsCells
    44. Logginidou HG, Li BH, Li DP, Lohmann JS, Schuler HG, DiVittore NA, Kreiser S, Cronin AJ. Propofol suppresses the cortical somatosensory evoked potential in rats. Anesth Analg. 2003 Dec; 97(6):1784-1788. PMID: 14633560.
      Citations: 16     Fields:    Translation:Animals
    45. Zahner MR, Li DP, Chen SR, Pan HL. Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats. J Physiol. 2003 Sep 01; 551(Pt 2):515-23. PMID: 12829722; PMCID: PMC2343227.
      Citations: 79     Fields:    Translation:AnimalsCells
    46. Li DP, Chen SR, Pan HL. Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition. J Neurosci. 2003 Jun 15; 23(12):5041-9. PMID: 12832527; PMCID: PMC6741207.
      Citations: 76     Fields:    Translation:AnimalsCells
    47. Khan GM, Li DP, Chen SR, Pan HL. Role of spinal nitric oxide in the inhibitory effect of [D-Pen2, D-Pen5]-enkephalin on ascending dorsal horn neurons in normal and diabetic rats. J Pharmacol Exp Ther. 2002 Dec; 303(3):1021-8. PMID: 12438523.
      Citations: 2     Fields:    Translation:AnimalsCells
    48. Li DP, Chen SR, Pan HL. Nitric oxide inhibits spinally projecting paraventricular neurons through potentiation of presynaptic GABA release. J Neurophysiol. 2002 Nov; 88(5):2664-74. PMID: 12424302.
      Citations: 48     Fields:    Translation:AnimalsCells
    49. Pan YZ, Li DP, Chen SR, Pan HL. Activation of delta-opioid receptors excites spinally projecting locus coeruleus neurons through inhibition of GABAergic inputs. J Neurophysiol. 2002 Nov; 88(5):2675-83. PMID: 12424303.
      Citations: 11     Fields:    Translation:AnimalsCells
    50. Li DP, Chen SR, Pan YZ, Levey AI, Pan HL. Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats. J Physiol. 2002 Sep 15; 543(Pt 3):807-18. PMID: 12231640; PMCID: PMC2290545.
      Citations: 61     Fields:    Translation:AnimalsCells
    51. Pan YZ, Li DP, Pan HL. Inhibition of glutamatergic synaptic input to spinal lamina II(o) neurons by presynaptic alpha(2)-adrenergic receptors. J Neurophysiol. 2002 Apr; 87(4):1938-47. PMID: 11929913.
      Citations: 41     Fields:    Translation:AnimalsCells
    52. Li DP, Pan YZ, Pan HL. Acetylcholine attenuates synaptic GABA release to supraoptic neurons through presynaptic nicotinic receptors. Brain Res. 2001 Nov 30; 920(1-2):151-8. PMID: 11716821.
      Citations: 7     Fields:    Translation:AnimalsCells
    53. Li DP, Pan HL. Potentiation of glutamatergic synaptic input to supraoptic neurons by presynaptic nicotinic receptors. Am J Physiol Regul Integr Comp Physiol. 2001 Oct; 281(4):R1105-13. PMID: 11557616.
      Citations: 7     Fields:    Translation:AnimalsCells
    54. Li DP, Averill DB, Pan HL. Differential roles for glutamate receptor subtypes within commissural NTS in cardiac-sympathetic reflex. Am J Physiol Regul Integr Comp Physiol. 2001 Sep; 281(3):R935-43. PMID: 11507011.
      Citations: 11     Fields:    Translation:Animals
    55. Zhang YJ, Li DP, Xue BJ, Wang YL, He RR. Effect of dipfluzine on L-type calcium current in guinea pig ventricular myocytes. Acta Pharmacol Sin. 2001 Aug; 22(8):701-5. PMID: 11749841.
      Citations:    Fields:    Translation:AnimalsCells
    56. Li DP, Pan HL. Responses of neurons in rostral ventrolateral medulla to activation of cardiac receptors in rats. Am J Physiol Heart Circ Physiol. 2000 Nov; 279(5):H2549-57. PMID: 11045993.
      Citations: 7     Fields:    Translation:AnimalsCells
    57. Chen S, Li DP, He RR. Effects of microinjection of adenosine into area postrema on heart rate, blood pressure and renal sympathetic nerve activity in rats. Sheng Li Xue Bao. 2000 Aug; 52(4):313-7. PMID: 11951114.
      Citations:    Fields:    Translation:Animals
    58. Tong QC, Zhang Y, Li DP, Zhou ZN, Ji YH. The blocking effect of BmP02, one novel short-chain scorpion peptide on transient outward K(+) channel of adult rat ventricular myocyte. Regul Pept. 2000 Jun 30; 90(1-3):85-92. PMID: 10828497.
      Citations: 3     Fields:    Translation:AnimalsCells
    59. Zhu Z, Li YL, Li DP, He RR. Effect of anoxic preconditioning on ATP-sensitive potassium channels in guinea-pig ventricular myocytes. Pflugers Arch. 2000 Apr; 439(6):808-13. PMID: 10784356.
      Citations: 1     Fields:    Translation:AnimalsCells
    60. Li DP, He RR. Intracarotid injection of endothelin-1 facilitates the activity of rostral ventrolateral medullary neurons via area postrema in rats. Sheng Li Xue Bao. 1999 Jun; 51(3):263-71. PMID: 11498987.
      Citations: 1     Fields:    Translation:AnimalsCells
    61. Li D, Li D, Zhang W, Sahin AA, Hittelman WN. DNA adducts in normal tissue adjacent to breast cancer: a review. Cancer Detect Prev. 1999; 23(6):454-62. PMID: 10571655.
      Citations: 20     Fields:    Translation:HumansCells
    62. Li DP, Fan ZZ, He RR. [Effects of endothelin on carotid baroreceptor activity in anesthetized rats]. Sheng Li Xue Bao. 1998 Oct; 50(5):532-8. PMID: 11367749.
      Citations: 1     Fields:    Translation:Animals
    63. Li DP, Fan ZZ, He RR. [Modulatory effects of endothelin on carotid baroreflex in anesthetized rats]. Sheng Li Xue Bao. 1998 Apr; 50(2):169-75. PMID: 11324531.
      Citations: 4     Fields:    Translation:Animals
    64. Upregulation of orexin receptor in paraventricular nucleus promotes sympathetic outflow in obese Zucker rats. Neuropharmacology. 99:481-490.
    65. Response to glutamate receptors and presympathetic neuronal hyperactivity of the central nervous system in hypertension. Hypertension. 62.
    66. Endogenous casein kinase-1 modulates NMDA receptor activity of hypothalamic presympathetic neurons and sympathetic outflow in hypertension. Journal of Physiology. 593:4439-4452.
    67. Correction. PLoS One. 8.
    68. Chronic Unpredictable Mild Stress Induces Loss of GABA Inhibition in Corticotrophin-Releasing Hormone-Expressing Neurons Through NKCC1 Upregulation. Neuroendocrinology.
    69. G9a is essential for epigenetic silencing of K+ channel genes in acute-to-chronic pain transition. Nature Neuroscience.
    70. The protective effects of chronic intermittent hypobaric hypoxia pretreatment against collagen-induced arthritis in rats. Journal of Inflammation (United Kingdom). 12.
    71. Acute stress diminishes M-current contributing to elevated activity of hypothalamic-pituitary-adrenal axis. Neuropharmacology. 114:67-76.
    72. Gabaergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding. Journal of Neuroscience. 35:3312-3318.
    73. Src Kinases Regulate Glutamatergic Input to Hypothalamic Presympathetic Neurons and Sympathetic Outflow in Hypertension. Hypertension. 69:154-162.
    74. Potentiation of glutamatergic synaptic input to supraoptic neurons by presynaptic nicotinic receptors. American Journal of Physiology. 281.
    75. Peripheral motor and sensory nerve conduction following transplantation of undifferentiated autologous adipose tissue-derived stem cells in a biodegradable U.S. food and drug administration-approved nerve conduit. Plastic and Reconstructive Surgery. 138:132-139.
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