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JACK A ROTH

TitleProfessor
InstitutionMD Anderson
DepartmentThoracic & Cardiovascular Surgery
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Deboever N, Correa AM, Feldman H, Eisenberg M, Antonoff MB, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Hofstetter WL. Early Interventional Treatment of High Output Chyle Leak following Esophagectomy is Associated with Improved Survival. Ann Surg. 2024 Apr 04. PMID: 38568206.
      Citations:    Fields:    
    2. Deboever N, Feldman H, Eisenberg M, Antonoff MB, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Hofstetter WL. Octreotide's role in the management of post-esophagectomy chylothorax. Dis Esophagus. 2024 Feb 22. PMID: 38391198.
      Citations:    Fields:    
    3. Deboever N, Bayley EM, Eisenberg MA, Hofstetter WL, Mehran RJ, Rice DC, Rajaram R, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Bednarski BK, Morris VK, Antonoff MB. Do resected colorectal cancer patients need early chest imaging? Impact of clinicopathologic characteristics on time to development of pulmonary metastases. J Surg Oncol. 2024 Feb; 129(2):331-337. PMID: 37876311.
      Citations:    Fields:    Translation:Humans
    4. Deboever N, Eisenberg M, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth J, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Antonoff MB. Circulomic variables predict pathologic staging preoperatively in treatment-na?ve non-small cell lung cancer. J Thorac Dis. 2023 Oct 31; 15(10):5507-5516. PMID: 37969292; PMCID: PMC10636430.
      Citations:    
    5. Feldman H, Sepesi B, Leung CH, Lin H, Weissferdt A, Pataer A, William WN, Walsh GL, Rice DC, Roth JA, Reza Md J M, Hofstetter WL, Antonoff MB, Rajaram R, Gibbons DL, Lee JJ, Heymach JV, Vaporciyan AA, Swisher SG, Cascone T, Feldman H, Sepesi B, Leung CH, Lin H, Weissferdt A, Pataer A, William WN, Walsh GL, Rice DC, Roth JA, Mehran RJ, Hofstetter WL, Antonoff MB, Rajaram R, Gibbons DL, Lee JJ, Heymach JV, Vaporciyan AA, Swisher SG, Cascone T. Surgical outcomes after chemotherapy plus nivolumab and chemotherapy plus nivolumab and ipilimumab in patients with non-small cell lung cancer. J Thorac Cardiovasc Surg. 2024 Apr; 167(4):1444-1453.e4. PMID: 37816395.
      Citations:    Fields:    Translation:Humans
    6. Lv X, Lu X, Cao J, Luo Q, Ding Y, Peng F, Pataer A, Lu D, Han D, Malmberg E, Chan DW, Wang X, Savage SR, Mao S, Yu J, Peng F, Yan L, Meng H, Maneix L, Han Y, Chen Y, Yao W, Chang EC, Catic A, Lin X, Miles G, Huang P, Sun Z, Burt B, Wang H, Wang J, Yao QC, Zhang B, Roth JA, O'Malley BW, Ellis MJ, Rimawi MF, Ying H, Chen X. Modulation of the proteostasis network promotes tumor resistance to oncogenic KRAS inhibitors. Science. 2023 09 08; 381(6662):eabn4180. PMID: 37676964; PMCID: PMC10720158.
      Citations: 2     Fields:    Translation:HumansCells
    7. Deboever N, Zhou N, McGrail DJ, Tomczak K, Oliva JL, Feldman HA, Parra E, Zhang J, Lee PP, Antonoff MB, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Swisher SS, Vaporciyan AA, Altan M, Weissferdt A, Tsao AS, Haymaker CL, Sepesi B. Radiographic response to neoadjuvant therapy in pleural mesothelioma should serve as a guide for patient selection for cytoreductive operations. Front Oncol. 2023; 13:1216999. PMID: 37637041; PMCID: PMC10455934.
      Citations:    
    8. Deboever N, Bayley EM, Eisenberg MA, Hofstetter WL, Mehran RJ, Rice DC, Rajaram R, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Bednarski BK, Morris VK, Antonoff MB. Lung surveillance following colorectal cancer pulmonary metastasectomy: Utilization of clinicopathologic risk factors to guide strategy. J Thorac Cardiovasc Surg. 2024 Mar; 167(3):814-819.e2. PMID: 37495170.
      Citations:    Fields:    Translation:Humans
    9. Faron M, Cheugoua-Zanetsie M, Tierney J, Thirion P, Nankivell M, Winter K, Yang H, Shapiro J, Vernerey D, Smithers BM, Walsh T, Piessen G, Nilsson M, Boonstra J, Ychou M, Law S, Cunningham D, de Vathaire F, Stahl M, Urba S, Valmasoni M, Williaume D, Thomas J, Lordick F, Tepper J, Roth J, Gebski V, Burmeister B, Paoletti X, van Sandick J, Fu J, Pignon JP, Ducreux M, Michiels S, MANATEC-02 Collaborative Group. Individual Participant Data Network Meta-Analysis of Neoadjuvant Chemotherapy or Chemoradiotherapy in Esophageal or Gastroesophageal Junction Carcinoma. J Clin Oncol. 2023 10 01; 41(28):4535-4547. PMID: 37467395; PMCID: PMC10553121.
      Citations: 1     Fields:    Translation:Humans
    10. Deboever N, Eisenberg MA, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rajaram R. Perspectives, risk factors, and coping mechanisms in patients with self-reported financial burden following lung cancer surgery. J Thorac Cardiovasc Surg. 2024 Feb; 167(2):478-487.e2. PMID: 37356476.
      Citations:    Fields:    
    11. Meraz IM, Majidi M, Fang B, Meng F, Gao L, Shao R, Song R, Li F, Lissanu Y, Chen H, Ha MJ, Wang Q, Wang J, Shpall E, Jung SY, Haderk F, Gui P, Riess JW, Olivas V, Bivona TG, Roth JA. Author Correction: 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib. Commun Biol. 2023 Jun 06; 6(1):608. PMID: 37280434; PMCID: PMC10244399.
      Citations:    
    12. Eisenberg M, Hofstetter WL, Mehran RJ, Rice DC, Roth J, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Antonoff MB, Rajaram R, Deboever N. Financial Toxicity in Patients With Resected Lung Cancer. Ann Surg. 2023 12 01; 278(6):1038-1044. PMID: 37249193.
      Citations:    Fields:    
    13. Meraz IM, Majidi M, Fang B, Meng F, Gao L, Shao R, Song R, Li F, Lissanu Y, Chen H, Ha MJ, Wang Q, Wang J, Shpall E, Jung SY, Haderk F, Gui P, Riess JW, Olivas V, Bivona TG, Roth JA. 3-Phosphoinositide-dependent kinase 1 drives acquired resistance to osimertinib. Commun Biol. 2023 05 11; 6(1):509. PMID: 37169941; PMCID: PMC10175489.
      Citations:    Translation:HumansAnimals
    14. Deboever N, Correa AM, Feldman H, Mathur U, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Walsh GL, Vaporciyan AA, Antonoff MB, Rajaram R. Disparities in early-stage lung cancer outcomes at minority-serving hospitals compared with nonminority serving hospitals. J Thorac Cardiovasc Surg. 2024 Jan; 167(1):329-337.e4. PMID: 37116780.
      Citations:    Fields:    
    15. Mitchell KG, Bayley EM, Ikoma N, Antonoff MB, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Maru DM, Erasmus JJ, Weston BR, Ajani JA, Badgwell BD, Hofstetter WL. Gastric Extent of Tumor Predicts Peritoneal Metastasis in Siewert II Adenocarcinoma. Ann Thorac Surg. 2024 Feb; 117(2):320-326. PMID: 37080372.
      Citations:    Fields:    
    16. Feldman HA, Zhou N, Deboever N, Hofstetter W, Mehran R, Rajaram R, Rice D, Roth JA, Sepesi B, Swisher S, Vaporciyan A, Walsh G, Godoy M, Strange C, Antonoff MB. Intraoperative challenges after induction therapy for non-small cell lung cancer: Effect of nodal disease on technical complexity. JTCVS Open. 2022 Dec; 12:372-384. PMID: 36590745; PMCID: PMC9801337.
      Citations: 2     
    17. Bayley EM, Ivy ML, Shewale JB, Ge PS, Antonoff MB, Francis AM, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Vaporciyan AA, Walsh GL, Lee JJ, Louie BE, Swisher SG, Bayley EM, Ivy ML, Shewale JB, Ge PS, Antonoff MB, Francis AM, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Vaporciyan AA, Walsh GL, Lee JJ, Louie BE, Swisher SG. High-Risk Features of Esophageal Adenocarcinoma Following Neoadjuvant Chemoradiation: Patients for Whom Surgery Should Not Be Delayed. Ann Surg. 2023 05 01; 277(5):721-726. PMID: 36052678.
      Citations:    
    18. Huang L, Wang J, Fang B, Meric-Bernstam F, Roth JA, Ha MJ. CombPDX: a unified statistical framework for evaluating drug synergism in patient-derived xenografts. Sci Rep. 2022 07 29; 12(1):12984. PMID: 35906256; PMCID: PMC9338066.
      Citations:    Fields:    
    19. Liu Y, Zhang Z, Rinsurongkawong W, Gay CM, Le X, Ning MS, Lewis J, Rinsurongkawong V, Lee JJ, Roth J, Swisher S, Gandhi S, Lee PP, Gibbons DL, Vaporciyan AA, Heymach JV, Zhang J, Lin SH. Association of Driver Oncogene Variations With Outcomes in Patients With Locally Advanced Non-Small Cell Lung Cancer Treated With Chemoradiation and Consolidative Durvalumab. JAMA Netw Open. 2022 06 01; 5(6):e2215589. PMID: 35666500; PMCID: PMC9171557.
      Citations:    Fields:    Translation:Humans
    20. Deboever N, Feldman HA, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Antonoff MB. The Role of Surgery in the Treatment of Melanoma Pulmonary Metastases in the Modern Era. J Surg Res. 2022 09; 277:125-130. PMID: 35489217.
      Citations:    Fields:    Translation:Humans
    21. Koc S, Lloyd MW, Grover JW, Xiao N, Seepo S, Subramanian SL, Ray M, Frech C, DiGiovanna J, Webster P, Neuhauser S, Srivastava A, Woo XY, Sanderson BJ, White B, Lott P, Dobrolecki LE, Dowst H, PDXNet Consortium , Evrard YA, Wallace TA, Moscow JA, Doroshow JH, Mitsiades N, Kaochar S, Pan CX, Chen MS, Carvajal-Carmona L, Welm AL, Welm BE, Lewis MT, Govindan R, Ding L, Li S, Herlyn M, Davies MA, Roth J, Meric-Bernstam F, Robinson PN, Bult CJ, Davis-Dusenbery B, Dean DA, Chuang JH. PDXNet portal: patient-derived Xenograft model, data, workflow and tool discovery. NAR Cancer. 2022 Jun; 4(2):zcac014. PMID: 35475145; PMCID: PMC9026194.
      Citations:    
    22. Alhalabi O, Chen J, Zhang Y, Lu Y, Wang Q, Ramachandran S, Tidwell RS, Han G, Yan X, Meng J, Wang R, Hoang AG, Wang WL, Song J, Lopez L, Andreev-Drakhlin A, Siefker-Radtke A, Zhang X, Benedict WF, Shah AY, Wang J, Msaouel P, Zhang M, Guo CC, Czerniak B, Behrens C, Soto L, Papadimitrakopoulou V, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee J, Roth J, Swisher S, Wistuba I, Heymach J, Wang J, Campbell MT, Efstathiou E, Titus M, Logothetis CJ, Ho TH, Zhang J, Wang L, Gao J. MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers. Nat Commun. 2022 04 04; 13(1):1797. PMID: 35379845; PMCID: PMC8980015.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    23. Meraz IM, Majidi M, Shao R, Meng F, Ha MJ, Shpall E, Roth JA. TUSC2 immunogene enhances efficacy of chemo-immuno combination on KRAS/LKB1 mutant NSCLC in humanized mouse model. Commun Biol. 2022 02 24; 5(1):167. PMID: 35210547; PMCID: PMC8873264.
      Citations:    Translation:Animals
    24. Zhang X, Zhang R, Ren C, Xu Y, Wu S, Meng C, Pataer A, Song X, Zhang J, Yao Y, He H, Chen H, Ma W, Wang J, Meric-Bernstam F, Champlin RE, Heymach JV, Rooney CM, Swisher SG, Vaporciyan AA, Roth JA, You MJ, Wang M, Fang B. Epstein Barr virus-positive B-cell lymphoma is highly vulnerable to MDM2 inhibitors in vivo. Blood Adv. 2022 02 08; 6(3):891-901. PMID: 34861697; PMCID: PMC8945299.
      Citations:    Fields:    Translation:HumansAnimalsCells
    25. Shah P, Frank ML, Jiang P, Sakellariou-Thompson D, Federico L, Khairullah R, Neutzler CA, Wistuba I, Chow CB, Long Y, Fujimoto J, Lin SY, Maitra A, Negrao MV, Mitchell KG, Weissferdt A, Vaporciyan AA, Cascone T, Roth JA, Zhang J, Sepesi B, Gibbons DL, Heymach JV, Haymaker CL, McGrail DJ, Reuben A, Bernatchez C, Forget MA. Combined IL-2, agonistic CD3 and 4-1BB stimulation preserve clonotype hierarchy in propagated non-small cell lung cancer tumor-infiltrating lymphocytes. J Immunother Cancer. 2022 02; 10(2). PMID: 35110355; PMCID: PMC8811607.
      Citations:    Fields:    Translation:HumansCells
    26. Pairawan S, Akcakanat A, Kopetz S, Tapia C, Zheng X, Chen H, Ha MJ, Rizvi Y, Holla V, Wang J, Evans KW, Zhao M, Busaidy N, Fang B, Roth JA, Dumbrava EI, Meric-Bernstam F. Combined MEK/MDM2 inhibition demonstrates antitumor efficacy in TP53 wild-type thyroid and colorectal cancers with MAPK alterations. Sci Rep. 2022 01 24; 12(1):1248. PMID: 35075200; PMCID: PMC8786858.
      Citations:    Fields:    Translation:HumansAnimalsCells
    27. Sepesi B, Zhou N, William WN, Lin HY, Leung CH, Weissferdt A, Mitchell KG, Pataer A, Walsh GL, Rice DC, Roth JA, Mehran RJ, Hofstetter WL, Antonoff MB, Rajaram R, Negrao MV, Tsao AS, Gibbons DL, Lee JJ, Heymach JV, Vaporciyan AA, Swisher SG, Cascone T. Surgical outcomes after neoadjuvant nivolumab or nivolumab with ipilimumab in patients with non-small cell lung cancer. J Thorac Cardiovasc Surg. 2022 11; 164(5):1327-1337. PMID: 35190177; PMCID: PMC10228712.
      Citations:    Fields:    
    28. Deboever N, McGrail DJ, Lee Y, Tran HT, Mitchell KG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Swisher SG, Vaporciyan AA, Walsh GL, Bernatchez C, Vailati Negrao M, Zhang J, Wistuba II, Heymach JV, Cascone T, Gibbons DL, Haymaker CL, Sepesi B. Surgical approach does not influence changes in circulating immune cell populations following lung cancer resection. Lung Cancer. 2022 02; 164:69-75. PMID: 35038676.
      Citations:    Fields:    Translation:HumansCells
    29. Sun H, Cao S, Mashl RJ, Mo CK, Zaccaria S, Wendl MC, Davies SR, Bailey MH, Primeau TM, Hoog J, Mudd JL, Dean DA, Patidar R, Chen L, Wyczalkowski MA, Jayasinghe RG, Rodrigues FM, Terekhanova NV, Li Y, Lim KH, Wang-Gillam A, Van Tine BA, Ma CX, Aft R, Fuh KC, Schwarz JK, Zevallos JP, Puram SV, Dipersio JF, NCI PDXNet Consortium, Davis-Dusenbery B, Ellis MJ, Lewis MT, Davies MA, Herlyn M, Fang B, Roth JA, Welm AL, Welm BE, Meric-Bernstam F, Chen F, Fields RC, Li S, Govindan R, Doroshow JH, Moscow JA, Evrard YA, Chuang JH, Raphael BJ, Ding L. Author Correction: Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidates for targeted treatment. Nat Commun. 2022 Jan 07; 13(1):294. PMID: 34996889; PMCID: PMC8742097.
      Citations:    Fields:    
    30. Zhou N, Hofstetter WL, Esophageal Squamous Cell Carcinoma Working Group, Mitchell KG, Bayley EM, Ajani JA, Antonoff MB, Betancourt SL, Blum-Murphy M, Feldman HA, Lin SH, Maru DM, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Weston BR. Salvage Esophagectomy Definition Influences Comparative Outcomes in Esophageal Squamous Cell Cancers. Ann Thorac Surg. 2022 12; 114(6):2032-2040. PMID: 34883083.
      Citations:    Fields:    
    31. Chang JY, Verma V, Feng L, Roth JA. SABR for operable stage I non-small-cell lung cancer: comparison to surgery - Authors' reply. Lancet Oncol. 2021 12; 22(12):e537-e538. PMID: 34856147.
      Citations:    Fields:    Translation:Humans
    32. Rice D, Rodriguez-Restrepo A, Mena G, Cata J, Thall P, Milton D, Correa A, Woodard T, Antonoff M, Hofstetter W, Roth J, Sepesi B, Swisher S, Walsh G, Vaporciyan A, Mehran R. Matched Pairs Comparison of an Enhanced Recovery Pathway Versus Conventional Management on Opioid Exposure and Pain Control in Patients Undergoing Lung Surgery. Ann Surg. 2021 12 01; 274(6):1099-1106. PMID: 32229762.
      Citations: 4     Fields:    Translation:Humans
    33. Thirion P, Nankivell M, Winter K, Cunningham D, Van der Gaast A, Law S, Langley R, Valmasoni M, Mauer M, Roth J, Gebski V, Burmeister BH, van Sandick J, Fu J, Tierney J, MANATEC-02 collaborative group, Faron M, Cheugoua-Zanetsie AM, de Vathaire F, Paoletti X, Ducreux M, Blanchard P, Pignon JP, Michiels S. Individual patient data meta-analysis of neoadjuvant chemotherapy followed by surgery versus upfront surgery for carcinoma of the oesophagus or the gastro-oesophageal junction. Eur J Cancer. 2021 11; 157:278-290. PMID: 34555647.
      Citations: 2     Fields:    Translation:Humans
    34. Chang JY, Mehran RJ, Feng L, Verma V, Liao Z, Welsh JW, Lin SH, O'Reilly MS, Jeter MD, Balter PA, McRae SE, Berry D, Heymach JV, Roth JA, STARS Lung Cancer Trials Group. Stereotactic ablative radiotherapy for operable stage I non-small-cell lung cancer (revised STARS): long-term results of a single-arm, prospective trial with prespecified comparison to surgery. Lancet Oncol. 2021 10; 22(10):1448-1457. PMID: 34529930; PMCID: PMC8521627.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    35. Sun H, Cao S, Mashl RJ, Mo CK, Zaccaria S, Wendl MC, Davies SR, Bailey MH, Primeau TM, Hoog J, Mudd JL, Dean DA, Patidar R, Chen L, Wyczalkowski MA, Jayasinghe RG, Rodrigues FM, Terekhanova NV, Li Y, Lim KH, Wang-Gillam A, Van Tine BA, Ma CX, Aft R, Fuh KC, Schwarz JK, Zevallos JP, Puram SV, Dipersio JF, NCI PDXNet Consortium, Davis-Dusenbery B, Ellis MJ, Lewis MT, Davies MA, Herlyn M, Fang B, Roth JA, Welm AL, Welm BE, Meric-Bernstam F, Chen F, Fields RC, Li S, Govindan R, Doroshow JH, Moscow JA, Evrard YA, Chuang JH, Raphael BJ, Ding L. Comprehensive characterization of 536 patient-derived xenograft models prioritizes candidatesfor targeted treatment. Nat Commun. 2021 08 24; 12(1):5086. PMID: 34429404; PMCID: PMC8384880.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    36. Bayley EM, Zhou N, Mitchell KG, Antonoff MB, Mehran RJ, Rice DC, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Cinciripini PM, Karam-Hage M, Roth JA, Hofstetter WL. Modern Perioperative Practices May Mitigate Effects of Continued Smoking Among Lung Cancer Patients. Ann Thorac Surg. 2022 07; 114(1):286-292. PMID: 34358522.
      Citations:    Fields:    Translation:Humans
    37. Negrao MV, Skoulidis F, Montesion M, Schulze K, Bara I, Shen V, Xu H, Hu S, Sui D, Elamin YY, Le X, Goldberg ME, Murugesan K, Wu CJ, Zhang J, Barreto DS, Robichaux JP, Reuben A, Cascone T, Gay CM, Mitchell KG, Hong L, Rinsurongkawong W, Roth JA, Swisher SG, Lee J, Tsao A, Papadimitrakopoulou V, Gibbons DL, Glisson BS, Singal G, Miller VA, Alexander B, Frampton G, Albacker LA, Shames D, Zhang J, Heymach JV. Oncogene-specific differences in tumor mutational burden, PD-L1 expression, and outcomes from immunotherapy in non-small cell lung cancer. J Immunother Cancer. 2021 08; 9(8). PMID: 34376553; PMCID: PMC8356172.
      Citations: 11     Fields:    Translation:Humans
    38. Blumenthaler AN, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Strange CD, Antonoff MB. Preoperative Maximum Standardized Uptake Value Associated With Recurrence Risk in Early Lung Cancer. Ann Thorac Surg. 2022 06; 113(6):1835-1844. PMID: 34252403; PMCID: PMC8742841.
      Citations:    Fields:    Translation:Humans
    39. Corsini EM, Mitchell KG, Zhou N, Bernatchez C, Haymaker CL, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Amaria RN, Jazaeri AA, Antonoff MB, Forget MA. Pulmonary resection for tissue harvest in adoptive tumor-infiltrating lymphocyte therapy: Safety and feasibility. J Surg Oncol. 2021 Sep; 124(4):699-703. PMID: 34057733.
      Citations: 1     Fields:    Translation:HumansCells
    40. Zhou N, Rice DC, Tsao AS, Lee PP, Haymaker CL, Corsini EM, Antonoff MB, Hofstetter WL, Rajaram R, Roth JA, Swisher SG, Vaporciyan AA, Walsh GL, Mehran RJ, Sepesi B. Extrapleural Pneumonectomy Versus Pleurectomy/Decortication for Malignant Pleural Mesothelioma. Ann Thorac Surg. 2022 01; 113(1):200-208. PMID: 33971174.
      Citations: 2     Fields:    Translation:Humans
    41. Woo XY, Giordano J, Srivastava A, Zhao ZM, Lloyd MW, de Bruijn R, Suh YS, Patidar R, Chen L, Scherer S, Bailey MH, Yang CH, Cortes-Sanchez E, Xi Y, Wang J, Wickramasinghe J, Kossenkov AV, Rebecca VW, Sun H, Mashl RJ, Davies SR, Jeon R, Frech C, Randjelovic J, Rosains J, Galimi F, Bertotti A, Lafferty A, O'Farrell AC, Modave E, Lambrechts D, Ter Brugge P, Marangoni E, El Botty R, Kim H, Kim JI, Yang HK, Lee C, Dean DA, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, Welm BE, Lewis MT, Fang B, Roth JA, Meric-Bernstam F, Herlyn M, Davies MA, Ding L, Li S, Govindan R, Isella C, Moscow JA, Trusolino L, Byrne AT, Jonkers J, Bult CJ, Medico E, Chuang JH, PDXNET Consortium, EurOPDX Consortium, Serra V. Author Correction: Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet. 2021 May; 53(5):761. PMID: 33608693; PMCID: PMC8110476.
      Citations: 1     Fields:    
    42. Zhou N, Corsini EM, Antonoff MB, Hofstetter WL, Mehran RJ, Rajaram R, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC. Robotic Surgery and Anatomic Segmentectomy: An Analysis of Trends, Patient Selection, and Outcomes. Ann Thorac Surg. 2022 03; 113(3):975-983. PMID: 33838123.
      Citations:    Fields:    Translation:Humans
    43. Cascone T, William WN, Weissferdt A, Leung CH, Lin HY, Pataer A, Godoy MCB, Carter BW, Federico L, Reuben A, Khan MAW, Dejima H, Francisco-Cruz A, Parra ER, Solis LM, Fujimoto J, Tran HT, Kalhor N, Fossella FV, Mott FE, Tsao AS, Blumenschein G, Le X, Zhang J, Skoulidis F, Kurie JM, Altan M, Lu C, Glisson BS, Byers LA, Elamin YY, Mehran RJ, Rice DC, Walsh GL, Hofstetter WL, Roth JA, Antonoff MB, Kadara H, Haymaker C, Bernatchez C, Ajami NJ, Jenq RR, Sharma P, Allison JP, Futreal A, Wargo JA, Wistuba II, Swisher SG, Lee JJ, Gibbons DL, Vaporciyan AA, Heymach JV, Sepesi B. Neoadjuvant nivolumab or nivolumab plus ipilimumab in operable non-small cell lung cancer: the phase 2 randomized NEOSTAR trial. Nat Med. 2021 03; 27(3):504-514. PMID: 33603241; PMCID: PMC8818318.
      Citations: 73     Fields:    Translation:HumansCTClinical Trials
    44. Corsini EM, Mitchell KG, Zhou N, Antonoff MB, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Hofstetter WL. Intestinal Metaplasia in the Esophageal Remnant Is Rare After Ivor Lewis Esophagectomy. J Gastrointest Surg. 2021 09; 25(9):2185-2191. PMID: 33555525.
      Citations: 1     Fields:    Translation:Humans
    45. Yuan G, Flores NM, Hausmann S, Lofgren SM, Kharchenko V, Angulo-Ibanez M, Sengupta D, Lu X, Czaban I, Azhibek D, Vicent S, Fischle W, Jaremko M, Fang B, Wistuba II, Chua KF, Roth JA, Minna JD, Shao NY, Jaremko L, Mazur PK, Gozani O. Elevated NSD3 histone methylation activity drives squamous cell lung cancer. Nature. 2021 02; 590(7846):504-508. PMID: 33536620; PMCID: PMC7895461.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    46. Gay CM, Stewart CA, Park EM, Diao L, Groves SM, Heeke S, Nabet BY, Fujimoto J, Solis LM, Lu W, Xi Y, Cardnell RJ, Wang Q, Fabbri G, Cargill KR, Vokes NI, Ramkumar K, Zhang B, Della Corte CM, Robson P, Swisher SG, Roth JA, Glisson BS, Shames DS, Wistuba II, Wang J, Quaranta V, Minna J, Heymach JV, Byers LA. Patterns of transcription factor programs and immune pathway activation define four major subtypes of SCLC with distinct therapeutic vulnerabilities. Cancer Cell. 2021 03 08; 39(3):346-360.e7. PMID: 33482121; PMCID: PMC8143037.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    47. Woo XY, Giordano J, Srivastava A, Zhao ZM, Lloyd MW, de Bruijn R, Suh YS, Patidar R, Chen L, Scherer S, Bailey MH, Yang CH, Cortes-Sanchez E, Xi Y, Wang J, Wickramasinghe J, Kossenkov AV, Rebecca VW, Sun H, Mashl RJ, Davies SR, Jeon R, Frech C, Randjelovic J, Rosains J, Galimi F, Bertotti A, Lafferty A, O'Farrell AC, Modave E, Lambrechts D, Ter Brugge P, Marangoni E, El Botty R, Kim H, Kim JI, Yang HK, Lee C, Dean DA, Davis-Dusenbery B, Evrard YA, Doroshow JH, Welm AL, Welm BE, Lewis MT, Fang B, Roth JA, Meric-Bernstam F, Herlyn M, Davies MA, Ding L, Li S, Govindan R, Isella C, Moscow JA, Trusolino L, Byrne AT, Jonkers J, Bult CJ, Medico E, Chuang JH, PDXNET Consortium, EurOPDX Consortium, Serra V. Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts. Nat Genet. 2021 01; 53(1):86-99. PMID: 33414553; PMCID: PMC7808565.
      Citations: 32     Fields:    Translation:HumansAnimals
    48. Corsini EM, Weissferdt A, Pataer A, Zhou N, Antonoff MB, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Cascone T, Heymach JV, Swisher SG, Sepesi B. Pathological nodal disease defines survival outcomes in patients with lung cancer with tumour major pathological response following neoadjuvant chemotherapy. Eur J Cardiothorac Surg. 2021 01 04; 59(1):100-108. PMID: 32864702.
      Citations: 8     Fields:    Translation:Humans
    49. Lam VK, Zhang J, Wu CC, Tran HT, Li L, Diao L, Wang J, Rinsurongkawong W, Raymond VM, Lanman RB, Lewis J, Roarty EB, Roth J, Swisher S, Lee JJ, Gibbons DL, Papadimitrakopoulou VA, Heymach JV. Genotype-Specific Differences in Circulating Tumor DNA Levels in Advanced NSCLC. J Thorac Oncol. 2021 04; 16(4):601-609. PMID: 33388476; PMCID: PMC8012216.
      Citations: 10     Fields:    Translation:Humans
    50. Le X, Negrao MV, Reuben A, Federico L, Diao L, McGrail D, Nilsson M, Robichaux J, Munoz IG, Patel S, Elamin Y, Fan YH, Lee WC, Parra E, Solis Soto LM, Chen R, Li J, Karpinets T, Khairullah R, Kadara H, Behrens C, Sepesi B, Wang R, Zhu M, Wang L, Vaporciyan A, Roth J, Swisher S, Haymaker C, Zhang J, Wang J, Wong KK, Byers LA, Bernatchez C, Zhang J, Wistuba II, Gibbons DL, Akbay EA, Heymach JV. Characterization of the Immune Landscape of EGFR-Mutant NSCLC Identifies CD73/Adenosine Pathway as a Potential Therapeutic Target. J Thorac Oncol. 2021 04; 16(4):583-600. PMID: 33388477.
      Citations: 18     Fields:    Translation:Animals
    51. Sitthideatphaiboon P, Galan-Cobo A, Negrao MV, Qu X, Poteete A, Zhang F, Liu DD, Lewis WE, Kemp HN, Lewis J, Rinsurongkawong W, Giri U, Lee JJ, Zhang J, Roth JA, Swisher S, Heymach JV. STK11/LKB1 Mutations in NSCLC Are Associated with KEAP1/NRF2-Dependent Radiotherapy Resistance Targetable by Glutaminase Inhibition. Clin Cancer Res. 2021 03 15; 27(6):1720-1733. PMID: 33323404; PMCID: PMC8138942.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    52. Zhang X, Zhang R, Chen H, Wang L, Ren C, Pataer A, Wu S, Meng QH, Ha MJ, Morris J, Xi Y, Wang J, Zhang J, Gibbons DL, Heymach JV, Meric-Bernstam F, Minna J, Swisher SG, Roth JA, Fang B. KRT-232 and navitoclax enhance trametinib's anti-Cancer activity in non-small cell lung cancer patient-derived xenografts with KRAS mutations. Am J Cancer Res. 2020; 10(12):4464-4475. PMID: 33415011; PMCID: PMC7783771.
      Citations: 7     
    53. Schwalk AJ, Ost DE, Saltijeral SN, De La Garza H, Casal RF, Jimenez CA, Eapen GA, Lewis J, Rinsurongkawong W, Rinsurongkawong V, Lee J, Elamin Y, Zhang J, Roth JA, Swisher S, Heymach JV, Grosu HB. Risk Factors for and Time to Recurrence of Symptomatic Malignant Pleural Effusion in Patients With Metastatic Non-Small Cell Lung Cancer with EGFR or ALK Mutations. Chest. 2021 03; 159(3):1256-1264. PMID: 33217413; PMCID: PMC8501006.
      Citations: 3     Fields:    Translation:Humans
    54. Corsini EM, Mitchell KG, Zhou N, Antonoff MB, Mehran RJ, Mena GE, Rajaram R, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC, Hofstetter WL. Liposomal Bupivacaine Intercostal Block Is Important for Reduction of Pulmonary Complications. Ann Thorac Surg. 2021 08; 112(2):423-429. PMID: 33129774.
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    55. Corsini EM, Zhou N, Antonoff MB, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Hofstetter WL. Postoperative Bleeding and Acute Kidney Injury in Esophageal Cancer Patients Receiving Ketorolac. Ann Thorac Surg. 2021 04; 111(4):1111-1117. PMID: 32980327.
      Citations:    Fields:    Translation:Humans
    56. Liu X, Hong L, Nilsson M, Hubert SM, Wu S, Rinsurongkawong W, Lewis J, Spelman A, Roth J, Swisher S, He Y, Jack Lee J, Fang B, Heymach JV, Zhang J, Le X. Concurrent use of aspirin with osimertinib is associated with improved survival in advanced EGFR-mutant non-small cell lung cancer. Lung Cancer. 2020 11; 149:33-40. PMID: 32956986; PMCID: PMC7577964.
      Citations: 2     Fields:    Translation:Humans
    57. Corsini EM, Foo WC, Mitchell KG, Zhou N, Maru DM, Ajani JA, Hofstetter WL, Esophageal Adenocarcinoma Working Group, Correa AM, Antonoff MB, Lin SH, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL. Esophageal adenocarcinoma with any component of signet ring cells portends poor prognosis and response to neoadjuvant therapy. J Thorac Cardiovasc Surg. 2021 Nov; 162(5):1404-1412.e2. PMID: 33010880.
      Citations: 2     Fields:    Translation:Humans
    58. Corsini EM, Mitchell KG, Zhou N, Antonoff MB, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Maru DM, Lin SH, Ajani JA, Hofstetter WL. Modified En Bloc Esophagectomy Compared With Standard Resection After Neoadjuvant Chemoradiation. Ann Thorac Surg. 2021 04; 111(4):1133-1140. PMID: 32857997.
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    59. Wang Q, Gu J, Wang L, Chang DW, Ye Y, Huang M, Roth JA, Wu X. Genetic associations of T cell cancer immune response-related genes with T cell phenotypes and clinical outcomes of early-stage lung cancer. J Immunother Cancer. 2020 08; 8(2). PMID: 32764075; PMCID: PMC7412613.
      Citations: 5     Fields:    Translation:HumansCells
    60. Corsini EM, Wang Q, Tran HT, Mitchell KG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Swisher SG, Vaporciyan AA, Walsh GL, Reuben A, Vasquez ME, Bernatchez C, Wang J, Cascone T, Zhang J, Heymach JV, Gibbons DL, Haymaker CL, Sepesi B. Peripheral cytokines are not influenced by the type of surgical approach for non-small cell lung cancer by four weeks postoperatively. Lung Cancer. 2020 08; 146:303-309. PMID: 32619781.
      Citations: 1     Fields:    Translation:Humans
    61. Corsini EM, Mitchell KG, Hofstetter WL, Mehran RJ, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Antonoff MB, Rice DC. Importance of resection for locoregional disease control in Masaoka stage IVA thymic neoplasms. J Surg Oncol. 2020 Sep; 122(3):515-522. PMID: 32468580.
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    62. Mitchell KG, Parra ER, Zhang J, Nelson DB, Corsini EM, Villalobos P, Moran CA, Skoulidis F, Wistuba II, Fujimoto J, Roth JA, Antonoff MB, MD Anderson Lung Cancer Immune Microenvironment Working Group. LKB1/STK11 Expression in Lung Adenocarcinoma and Associations With Patterns of Recurrence. Ann Thorac Surg. 2020 10; 110(4):1131-1138. PMID: 32442617; PMCID: PMC8215648.
      Citations: 3     Fields:    Translation:Humans
    63. Hong L, Negrao MV, Dibaj SS, Chen R, Reuben A, Bohac JM, Liu X, Skoulidis F, Gay CM, Cascone T, Mitchell KG, Tran HT, Le X, Byers LA, Sepesi B, Altan M, Elamin YY, Fossella FV, Kurie JM, Lu C, Mott FE, Tsao AS, Rinsurongkawong W, Lewis J, Gibbons DL, Glisson BS, Blumenschein GR, Roarty EB, Futreal PA, Wistuba II, Roth JA, Swisher SG, Papadimitrakopoulou VA, Heymach JV, Lee JJ, Simon GR, Zhang J. Programmed Death-Ligand 1 Heterogeneity and Its Impact on Benefit From Immune Checkpoint Inhibitors in NSCLC. J Thorac Oncol. 2020 09; 15(9):1449-1459. PMID: 32389639.
      Citations: 39     Fields:    Translation:Humans
    64. Shewale JB, Corsini EM, Correa AM, Brown EL, Leon-Novelo LG, Nyitray AG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth J, Walsh GL, Vaporciyan AA, Swisher SG, Sepesi B. Time trends and predictors of survival in surgically resected early-stage non-small cell lung cancer patients. J Surg Oncol. 2020 Sep; 122(3):495-505. PMID: 32356321.
      Citations: 3     Fields:    Translation:Humans
    65. Wu X, Wen CP, Ye Y, Tsai M, Wen C, Roth JA, Pu X, Chow WH, Huff C, Cunningham S, Huang M, Wu S, Tsao CK, Gu J, Lippman SM. Author Correction: Personalized Risk Assessment in Never, Light, and Heavy Smokers in a prospective cohort in Taiwan. Sci Rep. 2020 Mar 23; 10(1):5514. PMID: 32251345; PMCID: PMC7090032.
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    66. Weissferdt A, Pataer A, Vaporciyan AA, Correa AM, Sepesi B, Moran CA, Wistuba II, Roth JA, Shewale JB, Heymach JV, Kalhor N, Cascone T, Hofstetter WL, Lee JJ, Swisher SG. Agreement on Major Pathological Response in NSCLC Patients Receiving Neoadjuvant Chemotherapy. Clin Lung Cancer. 2020 07; 21(4):341-348. PMID: 32279936; PMCID: PMC7305995.
      Citations: 23     Fields:    Translation:Humans
    67. Van Haren RM, Correa AM, Sepesi B, Rice DC, Hofstetter WL, Roth JA, Swisher SG, Walsh GL, Vaporciyan AA, Mehran RJ, Antonoff MB. Hospital readmissions after pulmonary resection: post-discharge nursing telephone assessment identifies high risk patients. J Thorac Dis. 2020 Mar; 12(3):184-190. PMID: 32274083; PMCID: PMC7139035.
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    68. Nelson DB, Mitchell KG, Wang J, Fujimoto J, Godoy M, Behrens C, Zheng X, Zhang J, Sepesi B, Vaporciyan AA, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Swisher SG, Moran CA, Kalhor N, Weissferdt A, Wistuba II, Roth JA, Antonoff MB. Immune regulatory markers of lepidic-pattern adenocarcinomas presenting as ground glass opacities. J Thorac Dis. 2020 Mar; 12(3):329-337. PMID: 32274099; PMCID: PMC7139029.
      Citations: 1     
    69. Corsini EM, Datar SS, Mitchell KG, Zhou N, Hofstetter WL, Mehran RJ, Rajaram R, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Blackmon SH, Loree JM, Morris VK, Antonoff MB. High mutational concordance between primary colorectal tumors and associated pulmonary metastases. J Surg Oncol. 2020 May; 121(6):984-989. PMID: 32077113.
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    70. Stewart CA, Gay CM, Xi Y, Sivajothi S, Sivakamasundari V, Fujimoto J, Bolisetty M, Hartsfield PM, Balasubramaniyan V, Chalishazar MD, Moran C, Kalhor N, Stewart J, Tran H, Swisher SG, Roth JA, Zhang J, de Groot J, Glisson B, Oliver TG, Heymach JV, Wistuba I, Robson P, Wang J, Byers LA. Single-cell analyses reveal increased intratumoral heterogeneity after the onset of therapy resistance in small-cell lung cancer. Nat Cancer. 2020 04; 1:423-436. PMID: 33521652; PMCID: PMC7842382.
      Citations: 52     Translation:HumansCells
    71. Rajaram R, Correa AM, Xu T, Nguyen QN, Antonoff MB, Rice D, Mehran R, Roth J, Walsh G, Swisher S, Hofstetter WL, Vaporciyan A, Cascone T, Tsao AS, Papadimitrakopoulou VA, Gandhi S, Liao Z, Sepesi B. Locoregional Control, Overall Survival, and Disease-Free Survival in Stage IIIA (N2) Non-Small-Cell Lung Cancer: Analysis of Resected and Unresected Patients. Clin Lung Cancer. 2020 07; 21(4):e294-e301. PMID: 32089476.
      Citations: 3     Fields:    Translation:Humans
    72. Mitchell KG, Nelson DB, Corsini EM, Correa AM, Erasmus JJ, Hofstetter WL, Mehran RJ, Roth JA, Swisher SG, Sepesi B, Walsh GL, Vaporciyan AA, Rice DC, Nguyen QN, Antonoff MB. Surveillance After Treatment of Non-Small-Cell Lung Cancer: A Call for Multidisciplinary Standardization. Innovations (Phila). 2020 Jan/Feb; 15(1):57-65. PMID: 31875755.
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    73. Van Haren RM, Rajaram R, Correa AM, Mehran RJ, Antonoff MB, Hofstetter WL, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC, Roth JA. Preoperative Heparin for Lung Cancer Resection Increases Risk of Reoperation for Bleeding. Semin Thorac Cardiovasc Surg. 2020 Summer; 32(2):337-343. PMID: 31857153.
      Citations: 1     Fields:    Translation:Humans
    74. Nelson DB, Mitchell KG, Weston BR, Betancourt S, Maru D, Rice DC, Mehran RJ, Sepesi B, Antonoff MB, Walsh GL, Swisher SG, Roth JA, Vaporciyan AA, Blum M, Hofstetter WL. Should endoscopic mucosal resection be attempted for cT2N0 esophageal cancer? Dis Esophagus. 2019 Dec 13; 32(10):1-6. PMID: 30888418.
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    75. Mulshine JL, Ujhazy P, Antman M, Burgess CM, Kuzmin I, Bunn PA, Johnson BE, Roth JA, Pass HI, Ross SM, Aldige CR, Wistuba II, Minna JD. From clinical specimens to human cancer preclinical models-a journey the NCI-cell line database-25 years later. J Cell Biochem. 2019 Dec 05. PMID: 31803961; PMCID: PMC7496084.
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    76. Zhuo M, Guan Y, Yang X, Hong L, Wang Y, Li Z, Chen R, Abbas HA, Chang L, Gong Y, Wu N, Zhong J, Chen W, Chen H, Dong Z, Zhu X, Li J, Wang Y, An T, Wu M, Wang Z, Wang J, Roarty EB, Rinsurongkawong W, Lewis J, Roth JA, Swisher SG, Lee JJ, Heymach JV, Wistuba II, Kalhor N, Yang L, Yi X, Futreal PA, Glisson BS, Xia X, Zhang J, Zhao J. The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma. Clin Cancer Res. 2020 02 15; 26(4):892-901. PMID: 31694833; PMCID: PMC7024651.
      Citations: 26     Fields:    Translation:Humans
    77. Pataer A, Ozpolat B, Shao R, Cashman NR, Plotkin SS, Samuel CE, Lin SH, Kabil NN, Wang J, Majidi M, Fang B, Roth JA, Vaporciyan AA, Wistuba II, Hung MC, Swisher SG. Therapeutic targeting of the PI4K2A/PKR lysosome network is critical for misfolded protein clearance and survival in cancer cells. Oncogene. 2020 01; 39(4):801-813. PMID: 31554935; PMCID: PMC6976521.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    78. Shewale JB, Correa AM, Brown EL, Leon-Novelo LG, Nyitray AG, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Roth J, Vaporciyan AA, Swisher SG, Sepesi B. Time Trends of Perioperative Outcomes in Early Stage Non-Small Cell Lung Cancer Resection Patients. Ann Thorac Surg. 2020 02; 109(2):404-411. PMID: 31539514.
      Citations: 3     Fields:    Translation:Humans
    79. Corsini EM, Mitchell KG, Sceusi EL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Swisher SG, Roth JA, Vaporciyan AA, Hofstetter WL, Antonoff MB. Multidisciplinary treatment of thymic neuroendocrine tumors: surgery remains a key component. J Thorac Dis. 2019 Aug; 11(8):3391-3398. PMID: 31559043; PMCID: PMC6753460.
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    80. Chen Y, Zhang R, Wang L, Correa AM, Pataer A, Xu Y, Zhang X, Ren C, Wu S, Meng QH, Fujimoto J, Jensen VB, Antonoff MB, Hofstetter WL, Mehran RJ, Pisimisis G, Rice DC, Sepesi B, Vaporciyan AA, Walsh GL, Swisher SG, Roth JA, Heymach JV, Fang B. Tumor characteristics associated with engraftment of patient-derived non-small cell lung cancer xenografts in immunocompromised mice. Cancer. 2019 11 01; 125(21):3738-3748. PMID: 31287557; PMCID: PMC7294643.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    81. Corsini EM, Mitchell KG, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Swisher SG, Roth JA, Hofstetter WL, Vaporciyan AA, Morris VK, Antonoff MB. Colorectal cancer mutations are associated with survival and recurrence after pulmonary metastasectomy. J Surg Oncol. 2019 Sep; 120(4):729-735. PMID: 31290159.
      Citations: 4     Fields:    Translation:Humans
    82. Zhang Y, Roth JA, Yu H, Ye Y, Xie K, Zhao H, Chang DW, Huang M, Li H, Qu J, Wu X. A 5-microRNA signature identified from serum microRNA profiling predicts survival in patients with advanced stage non-small cell lung cancer. Carcinogenesis. 2019 07 04; 40(5):643-650. PMID: 30428030; PMCID: PMC6610172.
      Citations: 17     Fields:    Translation:Humans
    83. Meraz IM, Majidi M, Meng F, Shao R, Ha MJ, Neri S, Fang B, Lin SH, Tinkey PT, Shpall EJ, Morris J, Roth JA. An Improved Patient-Derived Xenograft Humanized Mouse Model for Evaluation of Lung Cancer Immune Responses. Cancer Immunol Res. 2019 08; 7(8):1267-1279. PMID: 31186248; PMCID: PMC7213862.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    84. Baity M, Wang L, Correa AM, Zhang X, Zhang R, Pataer A, Wu S, Meng QH, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Zhao M, Gu J, Fang B. Glutathione reductase (GSR) gene deletion and chromosome 8 aneuploidy in primary lung cancers detected by fluorescence in situ hybridization. Am J Cancer Res. 2019; 9(6):1201-1211. PMID: 31285952; PMCID: PMC6610060.
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    85. Mitchell KG, Parra ER, Nelson DB, Zhang J, Wistuba II, Fujimoto J, Roth JA, Antonoff MB, MD Anderson Lung Cancer Immune Microenvironment Working Group. Tumor cellular proliferation is associated with enhanced immune checkpoint expression in stage I non-small cell lung cancer. J Thorac Cardiovasc Surg. 2019 09; 158(3):911-919.e6. PMID: 31235357; PMCID: PMC8073227.
      Citations: 6     Fields:    Translation:Humans
    86. Mitchell KG, Ikoma N, Nelson DB, Maru DM, Erasmus JJ, Weston BR, Vaporciyan AA, Antonoff MB, Mehran RJ, Rice DC, Roth JA, Swisher SG, Sepesi B, Walsh GL, Correa AM, Das P, Blum MA, Badgwell BD, Hofstetter WL. Mediastinal Nodal Involvement After Neoadjuvant Chemoradiation for Siewert II/III Adenocarcinoma. Ann Thorac Surg. 2019 09; 108(3):845-851. PMID: 31102632.
      Citations: 4     Fields:    Translation:Humans
    87. Nelson DB, Mehran RJ, Mitchell KG, Rajaram R, Correa AM, Bassett RL, Antonoff MB, Hofstetter WL, Roth JA, Sepesi B, Swisher SG, Walsh GL, Vaporciyan AA, Rice DC. Robotic-Assisted Lobectomy for Non-Small Cell Lung Cancer: A Comprehensive Institutional Experience. Ann Thorac Surg. 2019 08; 108(2):370-376. PMID: 31004583.
      Citations: 13     Fields:    Translation:Humans
    88. Nelson DB, Rice DC, Mitchell KG, Tsao AS, Vaporciyan AA, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Gomez DR, Mehran RJ, Sepesi B. Defining the role of adjuvant radiotherapy for malignant pleural mesothelioma: a propensity-matched landmark analysis of the National Cancer Database. J Thorac Dis. 2019 Apr; 11(4):1269-1278. PMID: 31179069; PMCID: PMC6531726.
      Citations: 2     
    89. Negrao MV, Lam VK, Reuben A, Rubin ML, Landry LL, Roarty EB, Rinsurongkawong W, Lewis J, Roth JA, Swisher SG, Gibbons DL, Wistuba II, Papadimitrakopoulou V, Glisson BS, Blumenschein GR, Lee JJ, Heymach JV, Zhang J. PD-L1 Expression, Tumor Mutational Burden, and Cancer Gene Mutations Are Stronger Predictors of Benefit from Immune Checkpoint Blockade than HLA Class I Genotype in Non-Small Cell Lung Cancer. J Thorac Oncol. 2019 06; 14(6):1021-1031. PMID: 30780001.
      Citations: 35     Fields:    Translation:Humans
    90. Kim MP, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Erasmus JJ, Swisher SG. Occult stage IIIA-N2 patients have excellent overall survival with initial surgery. J Thorac Dis. 2018 Dec; 10(12):6670-6676. PMID: 30746212; PMCID: PMC6344762.
      Citations: 5     
    91. Pu X, Zhang R, Wang L, Chen Y, Xu Y, Pataer A, Meraz IM, Zhang X, Wu S, Wu L, Su D, Mao W, Heymach JV, Roth JA, Swisher SG, Fang B. Patient-derived tumor immune microenvironments in patient-derived xenografts of lung cancer. J Transl Med. 2018 11 26; 16(1):328. PMID: 30477533; PMCID: PMC6260563.
      Citations: 7     Fields:    Translation:HumansCells
    92. Nelson DB, Tayob N, Mitchell KG, Correa AM, Hofstetter WL, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Antonoff MB, Roth JA, Rice DC, Vauthey JN, Mehran RJ. Surgical margins and risk of local recurrence after wedge resection of colorectal pulmonary metastases. J Thorac Cardiovasc Surg. 2019 04; 157(4):1648-1655. PMID: 30635188.
      Citations: 5     Fields:    Translation:Humans
    93. Yan X, Zhang X, Wang L, Zhang R, Pu X, Wu S, Li L, Tong P, Wang J, Meng QH, Jensen VB, Girard L, Minna JD, Roth JA, Swisher SG, Heymach JV, Fang B. Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis. Cancer Res. 2019 01 01; 79(1):125-132. PMID: 30401714; PMCID: PMC7293542.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    94. Van Haren RM, Correa AM, Sepesi B, Rice DC, Hofstetter WL, Mehran RJ, Vaporciyan AA, Walsh GL, Roth JA, Swisher SG, Antonoff MB. Ground Glass Lesions on Chest Imaging: Evaluation of Reported Incidence in Cancer Patients Using Natural Language Processing. Ann Thorac Surg. 2019 03; 107(3):936-940. PMID: 30612991.
      Citations: 4     Fields:    Translation:Humans
    95. Xie Y, Lu W, Wang S, Tang X, Tang H, Zhou Y, Moran C, Behrens C, Roth JA, Zhou Q, Johnson DH, Swisher SG, Heymach JV, Papadimitrakopoulou VA, Xiao G, Minna JD, Wistuba II. Validation of the 12-gene Predictive Signature for Adjuvant Chemotherapy Response in Lung Cancer. Clin Cancer Res. 2019 01 01; 25(1):150-157. PMID: 30287547; PMCID: PMC7274213.
      Citations: 8     Fields:    Translation:HumansCells
    96. Elamin YY, Gomez DR, Antonoff MB, Robichaux JP, Tran H, Shorter MK, Bohac JM, Negrao MV, Le X, Rinsurogkawong W, Lewis J, Lacerda L, Roarty EB, Swisher SG, Roth JA, Zhang J, Papadimitrakopoulou V, Heymach JV. Local Consolidation Therapy (LCT) After First Line Tyrosine Kinase Inhibitor (TKI) for Patients With EGFR Mutant Metastatic Non-small-cell Lung Cancer (NSCLC). Clin Lung Cancer. 2019 01; 20(1):43-47. PMID: 30343004.
      Citations: 20     Fields:    Translation:Humans
    97. Le X, Puri S, Negrao MV, Nilsson MB, Robichaux J, Boyle T, Hicks JK, Lovinger KL, Roarty E, Rinsurongkawong W, Tang M, Sun H, Elamin Y, Lacerda LC, Lewis J, Roth JA, Swisher SG, Lee JJ, William WN, Glisson BS, Zhang J, Papadimitrakopoulou VA, Gray JE, Heymach JV. Landscape of EGFR-Dependent and -Independent Resistance Mechanisms to Osimertinib and Continuation Therapy Beyond Progression in EGFR-Mutant NSCLC. Clin Cancer Res. 2018 12 15; 24(24):6195-6203. PMID: 30228210; PMCID: PMC6295279.
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    98. Lam VK, Tran HT, Banks KC, Lanman RB, Rinsurongkawong W, Peled N, Lewis J, Lee JJ, Roth J, Roarty EB, Swisher S, Talasaz A, Futreal PA, Papadimitrakopoulou V, Heymach JV, Zhang J. Targeted Tissue and Cell-Free Tumor DNA Sequencing of Advanced Lung Squamous-Cell Carcinoma Reveals Clinically Significant Prevalence of Actionable Alterations. Clin Lung Cancer. 2019 01; 20(1):30-36.e3. PMID: 30279110.
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    99. Nelson DB, Lapid DJ, Mitchell KG, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Antonoff MB. Perioperative Outcomes for Stage I Non-Small Cell Lung Cancer: Differences Between Men and Women. Ann Thorac Surg. 2018 11; 106(5):1499-1503. PMID: 30118712.
      Citations: 1     Fields:    Translation:Humans
    100. Shewale JB, Mitchell KG, Nelson DB, Conley AP, Rice DC, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Mehran RJ, Vaporciyan AA, Weissferdt A, Sepesi B. Predictors of survival after resection of primary sarcomas of the chest wall-A large, single-institution series. J Surg Oncol. 2018 Sep; 118(3):518-524. PMID: 30109699.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    101. Nelson DB, Rice DC, Niu J, Atay SM, Vaporciyan AA, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Tsao AS, Gomez DR, Giordano SH, Mehran RJ, Sepesi B. Predictors of trimodality therapy and trends in therapy for malignant pleural mesothelioma. Eur J Cardiothorac Surg. 2018 05 01; 53(5):960-966. PMID: 29211849.
      Citations: 10     Fields:    Translation:Humans
    102. Pataer A, Shao R, Correa AM, Behrens C, Roth JA, Vaporciyan AA, Wistuba II, Swisher SG. Major pathologic response and RAD51 predict survival in lung cancer patients receiving neoadjuvant chemotherapy. Cancer Med. 2018 06; 7(6):2405-2414. PMID: 29673125; PMCID: PMC6010873.
      Citations: 9     Fields:    Translation:Humans
    103. Nelson DB, Godoy MCB, Benveniste MF, Shewale JB, Spicer JD, Mitchell KG, Hofstetter WL, Mehran RJ, Rice DC, Sepesi B, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Antonoff MB. Clinicoradiographic Predictors of Aggressive Biology in Lung Cancer With Ground Glass Components. Ann Thorac Surg. 2018 07; 106(1):235-241. PMID: 29534957.
      Citations: 2     Fields:    Translation:Humans
    104. Van Haren RM, Mehran RJ, Mena GE, Correa AM, Antonoff MB, Baker CM, Woodard TC, Hofstetter WL, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC. Enhanced Recovery Decreases Pulmonary and Cardiac Complications After Thoracotomy for Lung Cancer. Ann Thorac Surg. 2018 07; 106(1):272-279. PMID: 29530770.
      Citations: 36     Fields:    Translation:Humans
    105. Mehran RJ, Martin LW, Roth JA. Comparison of outcomes between muscle-sparing thoracotomy and video-assisted thoracic surgery in patients with cT1 N0 M0 lung cancer. J Thorac Cardiovasc Surg. 2018 Mar; 155(3):1307. PMID: 29452469.
      Citations:    Fields:    Translation:Humans
    106. Sepesi B, Ye Y, Mitchell KG, Zhang L, Gu J, Ji L, Antonoff MB, Hofstetter WL, Rice DC, Mehran RJ, Walsh GL, Vaporciyan AA, Swisher SG, Roth JA, Wu X. Genetic variants in cytokine signaling pathways and clinical outcomes in early-stage lung cancer patients. J Thorac Cardiovasc Surg. 2018 06; 155(6):2635-2645.e15. PMID: 29548588.
      Citations: 2     Fields:    Translation:HumansCells
    107. Shewale JB, Nelson DB, Rice DC, Sepesi B, Hofstetter WL, Mehran RJ, Vaporciyan AA, Walsh GL, Swisher SG, Roth JA, Antonoff MB. Natural History of Ground-Glass Lesions Among Patients With Previous Lung Cancer. Ann Thorac Surg. 2018 06; 105(6):1671-1677. PMID: 29432718.
      Citations: 6     Fields:    Translation:Humans
    108. Harada K, Wang X, Shimodaira Y, Sagebiel T, Bhutani MS, Lee JH, Weston B, Elimova E, Lin Q, Amlashi FG, Mizrak Kaya D, Lopez A, Blum Murphy MA, Roth JA, Swisher SG, Skinner HD, Hofstetter WL, Rogers JE, Thomas I, Maru DM, Komaki R, Walsh G, Ajani JA. Early Metabolic Change after Induction Chemotherapy Predicts Histologic Response and Prognosis in Patients with Esophageal Cancer: Secondary Analysis of a Randomized Trial. Target Oncol. 2018 02; 13(1):99-106. PMID: 29218623; PMCID: PMC5826863.
      Citations: 3     Fields:    Translation:Humans
    109. Meraz IM, Majidi M, Cao X, Lin H, Li L, Wang J, Baladandayuthapani V, Rice D, Sepesi B, Ji L, Roth JA. TUSC2 Immunogene Therapy Synergizes with Anti-PD-1 through Enhanced Proliferation and Infiltration of Natural Killer Cells in Syngeneic Kras-Mutant Mouse Lung Cancer Models. Cancer Immunol Res. 2018 02; 6(2):163-177. PMID: 29339375; PMCID: PMC5909977.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    110. Shimodaira Y, Slack RS, Harada K, Chen HC, Sagebiel T, Bhutani MS, Lee JH, Weston B, Elimova E, Lin Q, Amlashi FG, Mizrak Kaya D, Blum MA, Roth JA, Swisher SG, Skinner HD, Hofstetter WL, Rogers JE, Mares J, Thomas I, Maru DM, Komaki R, Walsh G, Ajani JA. Influence of induction chemotherapy in trimodality therapy-eligible oesophageal cancer patients: secondary analysis of a randomised trial. Br J Cancer. 2018 02 06; 118(3):331-337. PMID: 29235564; PMCID: PMC5808035.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    111. Wang JF, Pu X, Zhang X, Chen K, Xi Y, Wang J, Mao X, Zhang J, Heymach JV, Antonoff MB, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Meng QH, Shaw KR, Eterovic AK, Fang B. Variants with a low allele frequency detected in genomic DNA affect the accuracy of mutation detection in cell-free DNA by next-generation sequencing. Cancer. 2018 03 01; 124(5):1061-1069. PMID: 29178133; PMCID: PMC5821585.
      Citations: 4     Fields:    Translation:HumansCells
    112. Cao X, Zhao Y, Wang J, Dai B, Gentile E, Lin J, Pu X, Ji L, Wu S, Meraz I, Majidi M, Roth JA. TUSC2 downregulates PD-L1 expression in non-small cell lung cancer (NSCLC). Oncotarget. 2017 Dec 08; 8(64):107621-107629. PMID: 29296193; PMCID: PMC5746095.
      Citations: 9     Fields:    
    113. Shen J, Ye Y, Chang DW, Huang M, Heymach JV, Roth JA, Wu X, Zhao H. Circulating metabolite profiles to predict overall survival in advanced non-small cell lung cancer patients receiving first-line chemotherapy. Lung Cancer. 2017 12; 114:70-78. PMID: 29173770; PMCID: PMC5715727.
      Citations: 6     Fields:    Translation:Humans
    114. Huang X, Cao M, Wu S, Wang L, Hu J, Mehran RJ, Roth JA, Swisher SG, Wang RY, Kantarjian HM, Andreeff M, Sun X, Fang B. Anti-leukemia activity of NSC-743380 in SULT1A1-expressing acute myeloid leukemia cells is associated with inhibitions of cFLIP expression and PI3K/AKT/mTOR activities. Oncotarget. 2017 Nov 24; 8(60):102150-102160. PMID: 29254232; PMCID: PMC5731942.
      Citations: 3     Fields:    
    115. Yan X, Wang L, Zhang R, Pu X, Wu S, Yu L, Meraz IM, Zhang X, Wang JF, Gibbons DL, Mehran RJ, Swisher SG, Roth JA, Fang B. Overcoming resistance to anti-PD immunotherapy in a syngeneic mouse lung cancer model using locoregional virotherapy. Oncoimmunology. 2017; 7(1):e1376156. PMID: 29296537; PMCID: PMC5739569.
      Citations: 8     Fields:    
    116. Zhang L, Lin J, Ye Y, Oba T, Gentile E, Lian J, Wang J, Zhao Y, Gu J, Wistuba II, Roth JA, Ji L, Wu X. Serum MicroRNA-150 Predicts Prognosis for Early-Stage Non-Small Cell Lung Cancer and Promotes Tumor Cell Proliferation by Targeting Tumor Suppressor Gene SRCIN1. Clin Pharmacol Ther. 2018 06; 103(6):1061-1073. PMID: 28891208; PMCID: PMC5893421.
      Citations: 16     Fields:    Translation:Humans
    117. Atay SM, Correa AM, Hofstetter WL, Mehran RJ, Rice DC, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh G, Antonoff MB. Perioperative Outcomes of Patients Undergoing Lobectomy on Clopidogrel. Ann Thorac Surg. 2017 Dec; 104(6):1821-1828. PMID: 28987393.
      Citations: 1     Fields:    Translation:Humans
    118. Lin J, Zandi R, Shao R, Gu J, Ye Y, Wang J, Zhao Y, Pertsemlidis A, Wistuba II, Wu X, Roth JA, Ji L. A miR-SNP biomarker linked to an increased lung cancer survival by miRNA-mediated down-regulation of FZD4 expression and Wnt signaling. Sci Rep. 2017 08 22; 7(1):9029. PMID: 28831115; PMCID: PMC5567228.
      Citations: 9     Fields:    Translation:HumansCells
    119. Nelson DB, Rice DC, Niu J, Atay S, Vaporciyan AA, Antonoff M, Hofstetter WL, Walsh GL, Swisher SG, Roth JA, Tsao A, Gomez D, Giordano SH, Mehran R, Sepesi B. Long-Term Survival Outcomes of Cancer-Directed Surgery for Malignant Pleural Mesothelioma: Propensity Score Matching Analysis. J Clin Oncol. 2017 Oct 10; 35(29):3354-3362. PMID: 28817374.
      Citations: 22     Fields:    Translation:Humans
    120. Gentile E, Oba T, Lin J, Shao R, Meng F, Cao X, Lin HY, Mourad M, Pataer A, Baladandayuthapani V, Cai D, Roth JA, Ji L. Cationic liquid crystalline nanoparticles for the delivery of synthetic RNAi-based therapeutics. Oncotarget. 2017 Jul 18; 8(29):48222-48239. PMID: 28637023; PMCID: PMC5564640.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    121. Li R, Gu J, Heymach JV, Shu X, Zhao L, Han B, Ye Y, Roth J, Wu X. Hypoxia pathway genetic variants predict survival of non-small-cell lung cancer patients receiving platinum-based chemotherapy. Carcinogenesis. 2017 04 01; 38(4):419-424. PMID: 28186269; PMCID: PMC5963494.
      Citations: 7     Fields:    Translation:HumansCells
    122. Bassuner JK, Rice DC, Antonoff MB, Correa AM, Walsh GL, Vaporciyan AA, Garg N, Sepesi B, Swisher SG, Hofstetter WL, Roth JA, Mehran RJ. Polytetrafluoroethylene or Acellular Dermal Matrix for Diaphragmatic Reconstruction? Ann Thorac Surg. 2017 Jun; 103(6):1710-1714. PMID: 28366460.
      Citations: 5     Fields:    Translation:Humans
    123. Sun B, Brooks ED, Komaki RU, Liao Z, Jeter MD, McAleer MF, Allen PK, Balter PA, Welsh JD, O'Reilly MS, Gomez D, Hahn SM, Roth JA, Mehran RJ, Heymach JV, Chang JY. 7-year follow-up after stereotactic ablative radiotherapy for patients with stage I non-small cell lung cancer: Results of a phase 2 clinical trial. Cancer. 2017 Aug 15; 123(16):3031-3039. PMID: 28346656; PMCID: PMC5544582.
      Citations: 56     Fields:    Translation:HumansCTClinical Trials
    124. Peters HL, Tripathi SC, Kerros C, Katayama H, Garber HR, St John LS, Federico L, Meraz IM, Roth JA, Sepesi B, Majidi M, Ruisaard K, Clise-Dwyer K, Roszik J, Gibbons DL, Heymach JV, Swisher SG, Bernatchez C, Alatrash G, Hanash S, Molldrem JJ. Serine Proteases Enhance Immunogenic Antigen Presentation on Lung Cancer Cells. Cancer Immunol Res. 2017 04; 5(4):319-329. PMID: 28254787; PMCID: PMC5673248.
      Citations: 6     Fields:    Translation:HumansCells
    125. Xiaobo C, Majidi M, Feng M, Shao R, Wang J, Zhao Y, Baladandayuthapani V, Song J, Fang B, Ji L, Mehran R, Roth JA. TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin. Sci Rep. 2016 11 15; 6:35741. PMID: 27845352; PMCID: PMC5109231.
      Citations: 10     Fields:    Translation:HumansCells
    126. Wu X, Wen CP, Ye Y, Tsai M, Wen C, Roth JA, Pu X, Chow WH, Huff C, Cunningham S, Huang M, Wu S, Tsao CK, Gu J, Lippman SM. Personalized Risk Assessment in Never, Light, and Heavy Smokers in a prospective cohort in Taiwan. Sci Rep. 2016 11 02; 6:36482. PMID: 27805040; PMCID: PMC5090352.
      Citations: 14     Fields:    Translation:Humans
    127. Spicer JD, Shewale JB, Antonoff MB, Correa AM, Hofstetter WB, Rice DC, Vaporciyan AA, Mehran RJ, Walsh GL, Roth JA, Swisher SG, Sepesi B. The Influence of Reconstructive Technique on Perioperative Pulmonary and Infectious Outcomes Following Chest Wall Resection. Ann Thorac Surg. 2016 Nov; 102(5):1653-1659. PMID: 27526650.
      Citations: 6     Fields:    Translation:Humans
    128. Mehran RJ, Roth JA. Quality of life after video-assisted surgery for lung cancer. Lancet Oncol. 2016 08; 17(8):e315-e316. PMID: 27511151.
      Citations:    Fields:    Translation:Humans
    129. Xu K, Lin J, Zandi R, Roth JA, Ji L. MicroRNA-mediated target mRNA cleavage and 3'-uridylation in human cells. Sci Rep. 2016 07 21; 6:30242. PMID: 27440378; PMCID: PMC4954961.
      Citations: 8     Fields:    Translation:HumansCells
    130. Lin J, Xu K, Roth JA, Ji L. Detection of siRNA-mediated target mRNA cleavage activities in human cells by a novel stem-loop array RT-PCR analysis. Biochem Biophys Rep. 2016 Jul 01; 6:16-23. PMID: 26949742; PMCID: PMC4776327.
      Citations: 6     
    131. Tu H, Heymach JV, Wen CP, Ye Y, Pierzynski JA, Roth JA, Wu X. Different dietary patterns and reduction of lung cancer risk: A large case-control study in the U.S. Sci Rep. 2016 05 27; 6:26760. PMID: 27230571; PMCID: PMC4882747.
      Citations: 8     Fields:    Translation:Humans
    132. Antonoff MB, Ragalie W, Correa AM, Spicer JD, Sepesi B, Roth JA, Walsh GL, Hofstetter WL, Swisher SG, Rice DC, Vaporciyan AA, Mehran RJ. Results of Postdischarge Nursing Telephone Assessments: Persistent Symptoms Common Among Pulmonary Resection Patients. Ann Thorac Surg. 2016 Jul; 102(1):276-81. PMID: 27083250.
      Citations: 4     Fields:    Translation:Humans
    133. Li R, Pu X, Chang JY, Ye Y, Komaki R, Minna JD, Roth JA, Han B, Wu X. MiRNA-Related Genetic Variations Associated with Radiotherapy-Induced Toxicities in Patients with Locally Advanced Non-Small Cell Lung Cancer. PLoS One. 2016; 11(3):e0150467. PMID: 26991123; PMCID: PMC4798772.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    134. Melkonian SC, Daniel CR, Ye Y, Pierzynski JA, Roth JA, Wu X. Glycemic Index, Glycemic Load, and Lung Cancer Risk in Non-Hispanic Whites. Cancer Epidemiol Biomarkers Prev. 2016 Mar; 25(3):532-9. PMID: 26944871; PMCID: PMC4780226.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    135. Lin J, Xu K, Wei J, Heimberger AB, Roth JA, Ji L. MicroRNA-124 suppresses tumor cell proliferation and invasion by targeting CD164 signaling pathway in non-small cell lung cancer. J Gene Ther. 2016 Feb; 2(1). PMID: 27376157; PMCID: PMC4927004.
      Citations: 16     
    136. Chang JY, Senan S, Smit EF, Roth JA. Stereotactic radiotherapy or surgery for early-stage non-small-cell lung cancer - Authors' reply. Lancet Oncol. 2016 Feb; 17(2):e42-e43. PMID: 26868349.
      Citations: 2     Fields:    Translation:Humans
    137. Li H, Hu J, Wu S, Wang L, Cao X, Zhang X, Dai B, Cao M, Shao R, Zhang R, Majidi M, Ji L, Heymach JV, Wang M, Pan S, Minna J, Mehran RJ, Swisher SG, Roth JA, Fang B. Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells. Oncotarget. 2016 Jan 19; 7(3):3548-58. PMID: 26657290; PMCID: PMC4823126.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    138. Lara-Guerra H, Roth JA. Gene Therapy for Lung Cancer. Crit Rev Oncog. 2016; 21(1-2):115-24. PMID: 27481008; PMCID: PMC5443620.
      Citations: 6     Fields:    Translation:HumansAnimals
    139. Sepesi B, Schmidt HE, Lada M, Correa AM, Walsh GL, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Ajani JA, Watson TJ, Swisher SG, Low DE, Hofstetter WL. Survival in Patients With Esophageal Adenocarcinoma Undergoing Trimodality Therapy Is Independent of Regional Lymph Node Location. Ann Thorac Surg. 2016 Mar; 101(3):1075-80; Discussion 1080-1. PMID: 26680311.
      Citations: 5     Fields:    Translation:Humans
    140. Chang JY, Senan S, Smit EF, Roth JA. Surgery versus SABR for resectable non-small-cell lung cancer - Authors' reply. Lancet Oncol. 2015 Aug; 16(8):e374-5. PMID: 26248841.
      Citations: 3     Fields:    Translation:Humans
    141. Hildebrandt MA, Roth JA, Vaporciyan AA, Pu X, Ye Y, Correa AM, Kim JY, Swisher SG, Wu X. Genetic variation in the TNF/TRAF2/ASK1/p38 kinase signaling pathway as markers for postoperative pulmonary complications in lung cancer patients. Sci Rep. 2015 Jul 13; 5:12068. PMID: 26165383; PMCID: PMC4499815.
      Citations: 7     Fields:    Translation:HumansCells
    142. Dai B, Yan S, Lara-Guerra H, Kawashima H, Sakai R, Jayachandran G, Majidi M, Mehran R, Wang J, Bekele BN, Baladandayuthapani V, Yoo SY, Wang Y, Ying J, Meng F, Ji L, Roth JA. Exogenous Restoration of TUSC2 Expression Induces Responsiveness to Erlotinib in Wildtype Epidermal Growth Factor Receptor (EGFR) Lung Cancer Cells through Context Specific Pathways Resulting in Enhanced Therapeutic Efficacy. PLoS One. 2015; 10(6):e0123967. PMID: 26053020; PMCID: PMC4460038.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    143. Chang JY, Senan S, Paul MA, Mehran RJ, Louie AV, Balter P, Groen HJ, McRae SE, Widder J, Feng L, van den Borne BE, Munsell MF, Hurkmans C, Berry DA, van Werkhoven E, Kresl JJ, Dingemans AM, Dawood O, Haasbeek CJ, Carpenter LS, De Jaeger K, Komaki R, Slotman BJ, Smit EF, Roth JA. Stereotactic ablative radiotherapy versus lobectomy for operable stage I non-small-cell lung cancer: a pooled analysis of two randomised trials. Lancet Oncol. 2015 Jun; 16(6):630-7. PMID: 25981812; PMCID: PMC4489408.
      Citations: 453     Fields:    Translation:HumansCTClinical Trials
    144. Guo C, Hao C, Shao R, Fang B, Correa AM, Hofstetter WL, Roth JA, Behrens C, Kalhor N, Wistuba II, Swisher SG, Pataer A. RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer. Oncotarget. 2015 May 10; 6(13):11114-24. PMID: 25798539; PMCID: PMC4484443.
      Citations: 3     Fields:    Translation:HumansCells
    145. Ye Y, Vaporciyan AA, Xing J, Huang M, Gu J, Roth JA, Lippman SM, Wu X, Kim ES. Telomere length and recurrence risk after curative resection in patients with early-stage non-small-cell lung cancer: a prospective cohort study. J Thorac Oncol. 2015 Feb; 10(2):302-8. PMID: 25299235; PMCID: PMC4305022.
      Citations: 8     Fields:    Translation:HumansCells
    146. Huang X, Cao M, Wang L, Wu S, Liu X, Li H, Zhang H, Wang RY, Sun X, Wei C, Baggerly KA, Roth JA, Wang M, Swisher SG, Fang B. Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380. Oncotarget. 2015 Jan 01; 6(1):345-54. PMID: 25514600; PMCID: PMC4381599.
      Citations: 8     Fields:    Translation:HumansCells
    147. Kim MP, Correa AM, Hofstetter W, Mehran R, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Erasmus JJ, Swisher SG. Limitations of 18F-2-deoxy-D-glucose positron emission tomography in N1 detection in patients with pathologic stage II-N1 and implications for management. Ann Thorac Surg. 2015 Feb; 99(2):414-20. PMID: 25497068.
      Citations: 1     Fields:    Translation:Humans
    148. Hao C, Wang L, Peng S, Cao M, Li H, Hu J, Huang X, Liu W, Zhang H, Wu S, Pataer A, Heymach JV, Eterovic AK, Zhang Q, Shaw KR, Chen K, Futreal A, Wang M, Hofstetter W, Mehran R, Rice D, Roth JA, Sepesi B, Swisher SG, Vaporciyan A, Walsh GL, Johnson FM, Fang B. Gene mutations in primary tumors and corresponding patient-derived xenografts derived from non-small cell lung cancer. Cancer Lett. 2015 Feb 01; 357(1):179-185. PMID: 25444907; PMCID: PMC4301580.
      Citations: 52     Fields:    Translation:HumansAnimals
    149. Gao W, Wang M, Wang L, Lu H, Wu S, Dai B, Ou Z, Zhang L, Heymach JV, Gold KA, Minna J, Roth JA, Hofstetter WL, Swisher SG, Fang B. Selective antitumor activity of ibrutinib in EGFR-mutant non-small cell lung cancer cells. J Natl Cancer Inst. 2014 Sep; 106(9). PMID: 25214559; PMCID: PMC4200057.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    150. Wu S, Wang L, Huang X, Cao M, Hu J, Li H, Zhang H, Sun X, Meng QH, Hofstetter WL, Roth JA, Swisher SG, Fang B. Prodrug oncrasin-266 improves the stability, pharmacokinetics, and safety of NSC-743380. Bioorg Med Chem. 2014 Oct 01; 22(19):5234-40. PMID: 25182964; PMCID: PMC4172508.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    151. Kuroda S, Tam J, Roth JA, Sokolov K, Ramesh R. EGFR-targeted plasmonic magnetic nanoparticles suppress lung tumor growth by abrogating G2/M cell-cycle arrest and inducing DNA damage. Int J Nanomedicine. 2014; 9:3825-39. PMID: 25143731; PMCID: PMC4134185.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    152. Nunez MI, Behrens C, Liu D, Lin YH, Lee JJ, Roth J, Heymach J, Swisher SG, Hong WK, Wistuba II, Stewart DJ. Membrane carbonic anhydrase IX expression and relapse risk in resected stage I-II non-small-cell lung cancer. J Thorac Oncol. 2014 May; 9(5):675-84. PMID: 24662455; PMCID: PMC4084898.
      Citations: 8     Fields:    Translation:Humans
    153. Pu X, Hildebrandt MA, Lu C, Roth JA, Stewart DJ, Zhao Y, Heist RS, Ye Y, Chang DW, Su L, Minna JD, Lippman SM, Spitz MR, Christiani DC, Wu X. Inflammation-related genetic variations and survival in patients with advanced non-small cell lung cancer receiving first-line chemotherapy. Clin Pharmacol Ther. 2014 Sep; 96(3):360-369. PMID: 24755914; PMCID: PMC4141040.
      Citations: 13     Fields:    Translation:Humans
    154. Chang JY, Li QQ, Xu QY, Allen PK, Rebueno N, Gomez DR, Balter P, Komaki R, Mehran R, Swisher SG, Roth JA. Stereotactic ablative radiation therapy for centrally located early stage or isolated parenchymal recurrences of non-small cell lung cancer: how to fly in a "no fly zone". Int J Radiat Oncol Biol Phys. 2014 Apr 01; 88(5):1120-8. PMID: 24661665.
      Citations: 79     Fields:    Translation:Humans
    155. Sanchez-Espiridion B, Chen M, Chang JY, Lu C, Chang DW, Roth JA, Wu X, Gu J. Telomere length in peripheral blood leukocytes and lung cancer risk: a large case-control study in Caucasians. Cancer Res. 2014 May 01; 74(9):2476-86. PMID: 24618342; PMCID: PMC4357479.
      Citations: 44     Fields:    Translation:HumansCells
    156. Stephens N, Rice D, Correa A, Hoffstetter W, Mehran R, Roth J, Walsh G, Vaporciyan A, Swisher S. Thoracoscopic lobectomy is associated with improved short-term and equivalent oncological outcomes compared with open lobectomy for clinical Stage I non-small-cell lung cancer: a propensity-matched analysis of 963 cases. Eur J Cardiothorac Surg. 2014 Oct; 46(4):607-13. PMID: 24603446.
      Citations: 36     Fields:    Translation:Humans
    157. Coscio A, Chang DW, Roth JA, Ye Y, Gu J, Yang P, Wu X. Genetic variants of the Wnt signaling pathway as predictors of recurrence and survival in early-stage non-small cell lung cancer patients. Carcinogenesis. 2014 Jun; 35(6):1284-91. PMID: 24517998; PMCID: PMC4043238.
      Citations: 8     Fields:    Translation:HumansCells
    158. Meng J, Majidi M, Fang B, Ji L, Bekele BN, Minna JD, Roth JA. The tumor suppressor gene TUSC2 (FUS1) sensitizes NSCLC to the AKT inhibitor MK2206 in LKB1-dependent manner. PLoS One. 2013; 8(10):e77067. PMID: 24146957; PMCID: PMC3798310.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    159. Lu H, Wang L, Gao W, Meng J, Dai B, Wu S, Minna J, Roth JA, Hofstetter WL, Swisher SG, Fang B. IGFBP2/FAK pathway is causally associated with dasatinib resistance in non-small cell lung cancer cells. Mol Cancer Ther. 2013 Dec; 12(12):2864-73. PMID: 24130049; PMCID: PMC3858413.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    160. Han L, Ravoori M, Wu G, Sakai R, Yan S, Singh S, Xu K, Roth JA, Ji L, Kundra V. Somatostatin receptor type 2-based reporter expression after plasmid-based in vivo gene delivery to non-small cell lung cancer. Mol Imaging. 2013 Oct; 12(7):1-10. PMID: 23962694; PMCID: PMC4103180.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    161. Guo C, Lu H, Gao W, Wang L, Lu K, Wu S, Pataer A, Huang M, El-Zein R, Lin T, Roth JA, Mehran R, Hofstetter W, Swisher SG, Wu X, Fang B. Insulin-like growth factor binding protein-2 level is increased in blood of lung cancer patients and associated with poor survival. PLoS One. 2013; 8(9):e74973. PMID: 24069370; PMCID: PMC3775736.
      Citations: 20     Fields:    Translation:Humans
    162. Sepesi B, Correa AM, Blum MA, Erasmus JJ, Lee JH, Maru DM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Welsh JW, Swisher SG, Hofstetter WL, University of Texas MD Anderson Esophageal Cancer Group, Francis AM. The influence of histopathologic tumor viability on long-term survival and recurrence rates following neoadjuvant therapy for esophageal adenocarcinoma. Ann Surg. 2013 Sep; 258(3):500-7. PMID: 24022442.
      Citations: 12     Fields:    Translation:Humans
    163. Shirvani SM, Chang JY, Roth JA. Can stereotactic ablative radiotherapy in early stage lung cancers produce comparable success as surgery? Thorac Surg Clin. 2013 Aug; 23(3):369-81. PMID: 23931020.
      Citations: 8     Fields:    Translation:Humans
    164. Dai B, Yoo SY, Bartholomeusz G, Graham RA, Majidi M, Yan S, Meng J, Ji L, Coombes K, Minna JD, Fang B, Roth JA. KEAP1-dependent synthetic lethality induced by AKT and TXNRD1 inhibitors in lung cancer. Cancer Res. 2013 Sep 01; 73(17):5532-43. PMID: 23824739; PMCID: PMC3868367.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    165. Ganeshan DM, Correa AM, Bhosale P, Vaporciyan AA, Rice D, Mehran RJ, Walsh GL, Iyer R, Roth JA, Swisher SG, Hofstetter WL. Diaphragmatic hernia after esophagectomy in 440 patients with long-term follow-up. Ann Thorac Surg. 2013 Oct; 96(4):1138-1145. PMID: 23810174.
      Citations: 21     Fields:    Translation:Humans
    166. Chang JY, Liu YH, Zhu Z, Welsh JW, Gomez DR, Komaki R, Roth JA, Swisher SG. Stereotactic ablative radiotherapy: a potentially curable approach to early stage multiple primary lung cancer. Cancer. 2013 Sep 15; 119(18):3402-10. PMID: 23798353; PMCID: PMC3775964.
      Citations: 28     Fields:    Translation:Humans
    167. Wang Y, Gu J, Roth JA, Hildebrandt MA, Lippman SM, Ye Y, Minna JD, Wu X. Pathway-based serum microRNA profiling and survival in patients with advanced stage non-small cell lung cancer. Cancer Res. 2013 Aug 01; 73(15):4801-9. PMID: 23774211; PMCID: PMC3760306.
      Citations: 47     Fields:    Translation:Humans
    168. Wu X, Wang L, Ye Y, Aakre JA, Pu X, Chang GC, Yang PC, Roth JA, Marks RS, Lippman SM, Chang JY, Lu C, Deschamps C, Su WC, Wang WC, Huang MS, Chang DW, Li Y, Pankratz VS, Minna JD, Hong WK, Hildebrandt MA, Hsiung CA, Yang P. Genome-wide association study of genetic predictors of overall survival for non-small cell lung cancer in never smokers. Cancer Res. 2013 Jul 01; 73(13):4028-38. PMID: 23704207; PMCID: PMC3719971.
      Citations: 27     Fields:    Translation:Humans
    169. David E, Thall PF, Kalhor N, Hofstetter WL, Rice DC, Roth JA, Swisher SG, Walsh GL, Vaporciyan AA, Wei C, Mehran RJ. Visceral pleural invasion is not predictive of survival in patients with lung cancer and smaller tumor size. Ann Thorac Surg. 2013 Jun; 95(6):1872-7; discussion 1877. PMID: 23643547; PMCID: PMC4365776.
      Citations: 13     Fields:    Translation:Humans
    170. Seurin D, Lombet A, Babajko S, Ricort JM, Godeau F. Insulin-like growth factor binding proteins increase intracellular calcium levels in two different cell lines. PLoS One. 2013; 8(3):e59323. PMID: 23527161; PMCID: PMC3602172.
      Citations: 6     Fields:    Translation:HumansCells
    171. Guo C, Shao R, Correa AM, Behrens C, Johnson FM, Raso MG, Prudkin L, Solis LM, Nunez MI, Fang B, Roth JA, Wistuba II, Swisher SG, Lin T, Pataer A. Prognostic significance of combinations of RNA-dependent protein kinase and EphA2 biomarkers for NSCLC. J Thorac Oncol. 2013 Mar; 8(3):301-8. PMID: 23370317; PMCID: PMC3573252.
      Citations: 12     Fields:    Translation:HumansCells
    172. Pu X, Roth JA, Hildebrandt MA, Ye Y, Wei H, Minna JD, Lippman SM, Wu X. MicroRNA-related genetic variants associated with clinical outcomes in early-stage non-small cell lung cancer patients. Cancer Res. 2013 Mar 15; 73(6):1867-75. PMID: 23378343; PMCID: PMC3602350.
      Citations: 17     Fields:    Translation:Humans
    173. He Y, Gong Y, Lin J, Chang DW, Gu J, Roth JA, Wu X. Ionizing radiation-induced ?-H2AX activity in whole blood culture and the risk of lung cancer. Cancer Epidemiol Biomarkers Prev. 2013 Mar; 22(3):443-51. PMID: 23300022; PMCID: PMC3601549.
      Citations: 3     Fields:    Translation:HumansCells
    174. Amini A, Lou F, Correa AM, Baldassarre R, Rimner A, Huang J, Roth JA, Swisher SG, Vaporciyan AA, Lin SH. Predictors for locoregional recurrence for clinical stage III-N2 non-small cell lung cancer with nodal downstaging after induction chemotherapy and surgery. Ann Surg Oncol. 2013 Jun; 20(6):1934-40. PMID: 23263700; PMCID: PMC3656229.
      Citations: 12     Fields:    Translation:Humans
    175. Blackmon SH, Stephens EH, Correa AM, Hofstetter W, Kim MP, Mehran RJ, Rice DC, Roth JA, Swisher SG, Walsh GL, Vaporciyan AA. Predictors of recurrent pulmonary metastases and survival after pulmonary metastasectomy for colorectal cancer. Ann Thorac Surg. 2012 Dec; 94(6):1802-9. PMID: 23063195.
      Citations: 25     Fields:    Translation:Humans
    176. Pu X, Ye Y, Spitz MR, Wang L, Gu J, Lippman SM, Hildebrandt MA, Hong WK, Minna JD, Roth JA, Yang P, Wu X. Predictors of survival in never-smokers with non-small cell lung cancer: a large-scale, two-phase genetic study. Clin Cancer Res. 2012 Nov 01; 18(21):5983-91. PMID: 22977190; PMCID: PMC3640870.
      Citations: 7     Fields:    Translation:Humans
    177. Chang JY, Liu H, Balter P, Komaki R, Liao Z, Welsh J, Mehran RJ, Roth JA, Swisher SG. Clinical outcome and predictors of survival and pneumonitis after stereotactic ablative radiotherapy for stage I non-small cell lung cancer. Radiat Oncol. 2012 Sep 10; 7:152. PMID: 22963661; PMCID: PMC3444889.
      Citations: 51     Fields:    Translation:HumansCTClinical Trials
    178. Blackmon SH, Correa AM, Skoracki R, Chevray PM, Kim MP, Mehran RJ, Rice DC, Roth JA, Swisher SG, Vaporciyan AA, Yu P, Walsh GL, Hofstetter WL. Supercharged pedicled jejunal interposition for esophageal replacement: a 10-year experience. Ann Thorac Surg. 2012 Oct; 94(4):1104-11; discussion 1111-3. PMID: 22939245.
      Citations: 11     Fields:    Translation:Humans
    179. Sepesi B, Swisher SG, Walsh GL, Correa A, Mehran RJ, Rice D, Roth J, Vaporciyan A, Hofstetter WL. Omental reinforcement of the thoracic esophagogastric anastomosis: an analysis of leak and reintervention rates in patients undergoing planned and salvage esophagectomy. J Thorac Cardiovasc Surg. 2012 Nov; 144(5):1146-50. PMID: 22939861.
      Citations: 17     Fields:    Translation:Humans
    180. Marks JL, Hofstetter W, Correa AM, Mehran RJ, Rice D, Roth J, Walsh G, Vaporciyan A, Erasmus J, Chang J, Maru D, Lee JH, Lee J, Ajani JA, Swisher SG. Salvage esophagectomy after failed definitive chemoradiation for esophageal adenocarcinoma. Ann Thorac Surg. 2012 Oct; 94(4):1126-32; discussion 1132-3. PMID: 22921233.
      Citations: 21     Fields:    Translation:Humans
    181. Huschka R, Barhoumi A, Liu Q, Roth JA, Ji L, Halas NJ. Gene silencing by gold nanoshell-mediated delivery and laser-triggered release of antisense oligonucleotide and siRNA. ACS Nano. 2012 Sep 25; 6(9):7681-91. PMID: 22862291; PMCID: PMC3888232.
      Citations: 70     Fields:    Translation:HumansCells
    182. Amini A, Correa AM, Komaki R, Chang JY, Tsao AS, Roth JA, Swisher SG, Rice DC, Vaporciyan AA, Lin SH. The role of consolidation therapy for stage III non-small cell lung cancer with persistent N2 disease after induction chemotherapy. Ann Thorac Surg. 2012 Sep; 94(3):914-20. PMID: 22819472; PMCID: PMC3468148.
      Citations: 5     Fields:    Translation:Humans
    183. Kim JY, Hildebrandt MA, Pu X, Ye Y, Correa AM, Vaporciyan AA, Wu X, Roth JA. Variations in the vascular endothelial growth factor pathway predict pulmonary complications. Ann Thorac Surg. 2012 Oct; 94(4):1079-84; discussion 1084-5. PMID: 22795057; PMCID: PMC3466075.
      Citations: 6     Fields:    Translation:Humans
    184. Manyam G, Payton MA, Roth JA, Abruzzo LV, Coombes KR. Relax with CouchDB--into the non-relational DBMS era of bioinformatics. Genomics. 2012 Jul; 100(1):1-7. PMID: 22609849; PMCID: PMC3383915.
      Citations: 9     Fields:    Translation:Humans
    185. Pataer A, Kalhor N, Correa AM, Raso MG, Erasmus JJ, Kim ES, Behrens C, Lee JJ, Roth JA, Stewart DJ, Vaporciyan AA, Wistuba II, Swisher SG, University of Texas M. D. Anderson Lung Cancer Collaborative Research Group. Histopathologic response criteria predict survival of patients with resected lung cancer after neoadjuvant chemotherapy. J Thorac Oncol. 2012 May; 7(5):825-32. PMID: 22481232; PMCID: PMC3465940.
      Citations: 109     Fields:    Translation:Humans
    186. Lu C, Stewart DJ, Lee JJ, Ji L, Ramesh R, Jayachandran G, Nunez MI, Wistuba II, Erasmus JJ, Hicks ME, Grimm EA, Reuben JM, Baladandayuthapani V, Templeton NS, McMannis JD, Roth JA. Phase I clinical trial of systemically administered TUSC2(FUS1)-nanoparticles mediating functional gene transfer in humans. PLoS One. 2012; 7(4):e34833. PMID: 22558101; PMCID: PMC3338819.
      Citations: 58     Fields:    Translation:HumansCTClinical Trials
    187. Liu X, Guo W, Wu S, Wang L, Wang J, Dai B, Kim ES, Heymach JV, Wang M, Girard L, Minna J, Roth JA, Swisher SG, Fang B. Antitumor activity of a novel STAT3 inhibitor and redox modulator in non-small cell lung cancer cells. Biochem Pharmacol. 2012 May 15; 83(10):1456-64. PMID: 22387047; PMCID: PMC3391570.
      Citations: 20     Fields:    Translation:HumansCells
    188. He Y, Zhou Z, Hofstetter WL, Zhou Y, Hu W, Guo C, Wang L, Guo W, Pataer A, Correa AM, Lu Y, Wang J, Diao L, Byers LA, Wistuba II, Roth JA, Swisher SG, Heymach JV, Fang B. Aberrant expression of proteins involved in signal transduction and DNA repair pathways in lung cancer and their association with clinical parameters. PLoS One. 2012; 7(2):e31087. PMID: 22348039; PMCID: PMC3277494.
      Citations: 28     Fields:    Translation:HumansCells
    189. Wagner KW, Ye Y, Lin J, Vaporciyan AA, Roth JA, Wu X. Genetic variations in epigenetic genes are predictors of recurrence in stage I or II non-small cell lung cancer patients. Clin Cancer Res. 2012 Jan 15; 18(2):585-92. PMID: 22252258; PMCID: PMC3373176.
      Citations: 11     Fields:    Translation:Humans
    190. Jayachandran G, Roth JA, Ji L. Analysis of protein-protein interaction using proteinchip array-based SELDI-TOF mass spectrometry. Methods Mol Biol. 2012; 818:217-26. PMID: 22083826; PMCID: PMC3369541.
      Citations: 2     Fields:    Translation:Cells
    191. Ji L, Jayachandran G, Roth JA. High throughput profiling of serum phosphoproteins/peptides using the SELDI-TOF-MS platform. Methods Mol Biol. 2012; 818:199-216. PMID: 22083825; PMCID: PMC3369544.
      Citations: 1     Fields:    Translation:HumansCells
    192. Harvin JA, Lahat G, Correa AM, Lee J, Maru D, Ajani J, Marom EM, Welsh J, Bhutani MS, Walsh G, Roth J, Mehran R, Vaporciyan A, Rice D, Swisher S, Hofstetter W. Neoadjuvant chemoradiotherapy followed by surgery for esophageal adenocarcinoma: significance of microscopically positive circumferential radial margins. J Thorac Cardiovasc Surg. 2012 Feb; 143(2):412-20. PMID: 22172216.
      Citations: 9     Fields:    Translation:Humans
    193. Zandi R, Xu K, Poulsen HS, Roth JA, Ji L. The effect of adenovirus-mediated gene expression of FHIT in small cell lung cancer cells. Cancer Invest. 2011 Dec; 29(10):683-91. PMID: 22085272; PMCID: PMC3372907.
      Citations: 5     Fields:    Translation:HumansCells
    194. Blackmon SH, Roth JA. Thoracic metastases from sarcoma: a commentary. Oncology (Williston Park). 2011 Nov 15; 25(12):1211-2. PMID: 22229215.
      Citations:    Fields:    Translation:Humans
    195. He Y, Correa AM, Raso MG, Hofstetter WL, Fang B, Behrens C, Roth JA, Zhou Y, Yu L, Wistuba II, Swisher SG, Pataer A. The role of PKR/eIF2a signaling pathway in prognosis of non-small cell lung cancer. PLoS One. 2011; 6(11):e24855. PMID: 22102852; PMCID: PMC3213082.
      Citations: 19     Fields:    Translation:HumansCells
    196. Yokoyama T, Tam J, Kuroda S, Scott AW, Aaron J, Larson T, Shanker M, Correa AM, Kondo S, Roth JA, Sokolov K, Ramesh R. EGFR-targeted hybrid plasmonic magnetic nanoparticles synergistically induce autophagy and apoptosis in non-small cell lung cancer cells. PLoS One. 2011; 6(11):e25507. PMID: 22087216; PMCID: PMC3210119.
      Citations: 28     Fields:    Translation:HumansCells
    197. Kim JY, Correa AM, Vaporciyan AA, Roth JA, Mehran RJ, Walsh GL, Rice DC, Ajani JA, Maru DM, Bhutani MS, Welsh J, Marom EM, Swisher SG, Hofstetter WL. Does the timing of esophagectomy after chemoradiation affect outcome? Ann Thorac Surg. 2012 Jan; 93(1):207-12; discussion 212-3. PMID: 21962263; PMCID: PMC4041623.
      Citations: 26     Fields:    Translation:Humans
    198. Kim MP, Chen Y, Bekele BN, Lopez A, Khanna A, Chen JQ, Spitz MR, Behrens C, Solis L, Wismach M, Ji L, Wistuba II, Roth JA, Katz RL. Activating enhancer-binding protein-2? nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection. Ann Thorac Surg. 2011 Sep; 92(3):1044-50. PMID: 21871297; PMCID: PMC3272351.
      Citations: 4     Fields:    Translation:HumansCells
    199. Xie Y, Xiao G, Coombes KR, Behrens C, Solis LM, Raso G, Girard L, Erickson HS, Roth J, Heymach JV, Moran C, Danenberg K, Minna JD, Wistuba II. Robust gene expression signature from formalin-fixed paraffin-embedded samples predicts prognosis of non-small-cell lung cancer patients. Clin Cancer Res. 2011 Sep 01; 17(17):5705-14. PMID: 21742808; PMCID: PMC3166982.
      Citations: 84     Fields:    Translation:Humans
    200. Gomez DR, Cox JD, Roth JA, Allen PK, Wei X, Mehran RJ, Kim JY, Swisher SG, Rice DC, Komaki R. A prospective phase 2 study of surgery followed by chemotherapy and radiation for superior sulcus tumors. Cancer. 2012 Jan 15; 118(2):444-51. PMID: 21713767; PMCID: PMC3465936.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    201. Dai J, Gu J, Lu C, Lin J, Stewart D, Chang D, Roth JA, Wu X. Genetic variations in the regulator of G-protein signaling genes are associated with survival in late-stage non-small cell lung cancer. PLoS One. 2011; 6(6):e21120. PMID: 21698121; PMCID: PMC3117866.
      Citations: 15     Fields:    Translation:HumansCells
    202. Lin J, Xu K, Gitanjali J, Roth JA, Ji L. Regulation of tumor suppressor gene FUS1 expression by the untranslated regions of mRNA in human lung cancer cells. Biochem Biophys Res Commun. 2011 Jul 01; 410(2):235-41. PMID: 21645495; PMCID: PMC3129382.
      Citations: 8     Fields:    Translation:HumansCells
    203. Wu X, Ye Y, Rosell R, Amos CI, Stewart DJ, Hildebrandt MA, Roth JA, Minna JD, Gu J, Lin J, Buch SC, Nukui T, Ramirez Serrano JL, Taron M, Cassidy A, Lu C, Chang JY, Lippman SM, Hong WK, Spitz MR, Romkes M, Yang P. Genome-wide association study of survival in non-small cell lung cancer patients receiving platinum-based chemotherapy. J Natl Cancer Inst. 2011 May 18; 103(10):817-25. PMID: 21483023; PMCID: PMC3096796.
      Citations: 42     Fields:    Translation:Humans
    204. Hemmati SH, Correa AM, Walsh GL, Swisher SG, Roth JA, Rice DC, Mehran RJ, Vaporciyan AA. The prognostic factors of chest wall metastasis resection. Eur J Cardiothorac Surg. 2011 Aug; 40(2):328-33. PMID: 21466960.
      Citations: 2     Fields:    Translation:Humans
    205. Dai B, Meng J, Peyton M, Girard L, Bornmann WG, Ji L, Minna JD, Fang B, Roth JA. STAT3 mediates resistance to MEK inhibitor through microRNA miR-17. Cancer Res. 2011 May 15; 71(10):3658-68. PMID: 21444672; PMCID: PMC3392199.
      Citations: 46     Fields:    Translation:HumansAnimalsCells
    206. Stephens EH, Blackmon SH, Correa AM, Roth JA, Rice DC, Hofstetter W, Benjamin R, Mehran R, Swisher SG, Walsh GL, Vaporciyan AA. Progression after chemotherapy is a novel predictor of poor outcomes after pulmonary metastasectomy in sarcoma patients. J Am Coll Surg. 2011 May; 212(5):821-6. PMID: 21435923.
      Citations: 15     Fields:    Translation:Humans
    207. Diao L, Clarke CH, Coombes KR, Hamilton SR, Roth J, Mao L, Czerniak B, Baggerly KA, Morris JS, Fung ET, Bast RC. Reproducibility of SELDI Spectra Across Time and Laboratories. Cancer Inform. 2011 Mar 14; 10:45-64. PMID: 21552492; PMCID: PMC3085423.
      Citations: 8     
    208. Stewart DJ, Behrens C, Roth J, Wistuba II. Exponential decay nonlinear regression analysis of patient survival curves: preliminary assessment in non-small cell lung cancer. Lung Cancer. 2011 Feb; 71(2):217-23. PMID: 20627364; PMCID: PMC2962880.
      Citations: 5     Fields:    Translation:Humans
    209. Shanker M, Jin J, Branch CD, Miyamoto S, Grimm EA, Roth JA, Ramesh R. Tumor suppressor gene-based nanotherapy: from test tube to the clinic. J Drug Deliv. 2011; 2011:465845. PMID: 21490751; PMCID: PMC3065904.
      Citations: 6     
    210. Nanjundan M, Byers LA, Carey MS, Siwak DR, Raso MG, Diao L, Wang J, Coombes KR, Roth JA, Mills GB, Wistuba II, Minna JD, Heymach JV. Proteomic profiling identifies pathways dysregulated in non-small cell lung cancer and an inverse association of AMPK and adhesion pathways with recurrence. J Thorac Oncol. 2010 Dec; 5(12):1894-904. PMID: 21124077; PMCID: PMC3374718.
      Citations: 27     Fields:    Translation:HumansCells
    211. Meng J, Dai B, Fang B, Bekele BN, Bornmann WG, Sun D, Peng Z, Herbst RS, Papadimitrakopoulou V, Minna JD, Peyton M, Roth JA. Combination treatment with MEK and AKT inhibitors is more effective than each drug alone in human non-small cell lung cancer in vitro and in vivo. PLoS One. 2010 Nov 29; 5(11):e14124. PMID: 21124782; PMCID: PMC2993951.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    212. Pataer A, Raso MG, Correa AM, Behrens C, Tsuta K, Solis L, Fang B, Roth JA, Wistuba II, Swisher SG. Prognostic significance of RNA-dependent protein kinase on non-small cell lung cancer patients. Clin Cancer Res. 2010 Nov 15; 16(22):5522-8. PMID: 20930042; PMCID: PMC3070287.
      Citations: 13     Fields:    Translation:Humans
    213. Meng J, Fang B, Liao Y, Chresta CM, Smith PD, Roth JA. Apoptosis induction by MEK inhibition in human lung cancer cells is mediated by Bim. PLoS One. 2010 Sep 27; 5(9):e13026. PMID: 20885957; PMCID: PMC2946397.
      Citations: 31     Fields:    Translation:HumansCells
    214. Swisher SG, Hofstetter W, Komaki R, Correa AM, Erasmus J, Lee JH, Liao Z, Maru D, Mehran R, Patel S, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Ajani JA. Improved long-term outcome with chemoradiotherapy strategies in esophageal cancer. Ann Thorac Surg. 2010 Sep; 90(3):892-8; discussion 898-9. PMID: 20732514.
      Citations: 23     Fields:    Translation:Humans
    215. Kim MP, Correa AM, Lee J, Rice DC, Roth JA, Mehran RJ, Walsh GL, Ajani JA, Maru DM, Chang JY, Marom EM, Macapinlac HA, Lee JH, Vaporciyan AA, Rice T, Swisher SG, Hofstetter WL. Pathologic T0N1 esophageal cancer after neoadjuvant therapy and surgery: an orphan status. Ann Thorac Surg. 2010 Sep; 90(3):884-90; discussion 890-1. PMID: 20732513.
      Citations: 12     Fields:    Translation:Humans
    216. Gaur P, Sepesi B, Hofstetter WL, Correa AM, Bhutani MS, Watson TJ, Swisher SG, M. D. Anderson Esophageal Cancer Group, University of Rochester School of Medicine and Dentistry Foregut Group. Endoscopic esophageal tumor length: a prognostic factor for patients with esophageal cancer. Cancer. 2011 Jan 01; 117(1):63-9. PMID: 20803613.
      Citations: 22     Fields:    Translation:Humans
    217. Hildebrandt MA, Komaki R, Liao Z, Gu J, Chang JY, Ye Y, Lu C, Stewart DJ, Minna JD, Roth JA, Lippman SM, Cox JD, Hong WK, Spitz MR, Wu X. Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer. PLoS One. 2010 Aug 25; 5(8):e12402. PMID: 20811626; PMCID: PMC2928273.
      Citations: 43     Fields:    Translation:HumansPHPublic Health
    218. Gjetting T, Arildsen NS, Christensen CL, Poulsen TT, Roth JA, Handlos VN, Poulsen HS. In vitro and in vivo effects of polyethylene glycol (PEG)-modified lipid in DOTAP/cholesterol-mediated gene transfection. Int J Nanomedicine. 2010 Aug 09; 5:371-83. PMID: 20957159; PMCID: PMC2950395.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    219. Jayachandran G, Ueda K, Wang B, Roth JA, Ji L. NPRL2 sensitizes human non-small cell lung cancer (NSCLC) cells to cisplatin treatment by regulating key components in the DNA repair pathway. PLoS One. 2010 Aug 05; 5(8):e11994. PMID: 20700484; PMCID: PMC2916838.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    220. Katz RL, He W, Khanna A, Fernandez RL, Zaidi TM, Krebs M, Caraway NP, Zhang HZ, Jiang F, Spitz MR, Blowers DP, Jimenez CA, Mehran RJ, Swisher SG, Roth JA, Morris JS, Etzel CJ, El-Zein R. Genetically abnormal circulating cells in lung cancer patients: an antigen-independent fluorescence in situ hybridization-based case-control study. Clin Cancer Res. 2010 Aug 01; 16(15):3976-87. PMID: 20651054; PMCID: PMC2949278.
      Citations: 21     Fields:    Translation:HumansCells
    221. Kim MP, Correa AM, Swisher SG, Hofstetter WL, Mehran RJ, Rice DC, Walsh GL, Erasmus J, Moran C, Vaporciyan AA, Roth JA. Non-small cell lung cancer resection in lymphoma patients. Ann Thorac Surg. 2010 Jul; 90(1):210-6. PMID: 20609777.
      Citations: 3     Fields:    Translation:Humans
    222. Gaur P, Hofstetter WL, Bekele BN, Correa AM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Rice TW, Swisher SG. Comparison between established and the Worldwide Esophageal Cancer Collaboration staging systems. Ann Thorac Surg. 2010 Jun; 89(6):1797-1803, 1804.e1-3; discussion 1803-4. PMID: 20494031.
      Citations: 8     Fields:    Translation:Humans
    223. Shanker M, Willcutts D, Roth JA, Ramesh R. Drug resistance in lung cancer. Lung Cancer (Auckl). 2010; 1:23-36. PMID: 28210104; PMCID: PMC5312467.
      Citations: 48     
    224. Christensen CL, Gjetting T, Poulsen TT, Cramer F, Roth JA, Poulsen HS. Targeted cytosine deaminase-uracil phosphoribosyl transferase suicide gene therapy induces small cell lung cancer-specific cytotoxicity and tumor growth delay. Clin Cancer Res. 2010 Apr 15; 16(8):2308-19. PMID: 20371678; PMCID: PMC3457699.
      Citations: 8     Fields:    Translation:AnimalsCells
    225. Ramesh R, Ioannides CG, Roth JA, Chada S. Adenovirus-mediated interleukin (IL)-24 immunotherapy for cancer. Methods Mol Biol. 2010; 651:241-70. PMID: 20686970.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    226. Tsao AS, Roth JA, Herbst RS. Surgery: Future directions in multimodality therapy for NSCLC. Nat Rev Clin Oncol. 2010 Jan; 7(1):10-2. PMID: 20029443.
      Citations:    Fields:    
    227. Nemunaitis J, Clayman G, Agarwala SS, Hrushesky W, Wells JR, Moore C, Hamm J, Yoo G, Baselga J, Murphy BA, Menander KA, Licato LL, Chada S, Gibbons RD, Olivier M, Hainaut P, Roth JA, Sobol RE, Goodwin WJ. Biomarkers Predict p53 Gene Therapy Efficacy in Recurrent Squamous Cell Carcinoma of the Head and Neck. Clin Cancer Res. 2009 Dec 15; 15(24):7719-7725. PMID: 19996201.
      Citations: 32     Fields:    
    228. Dai B, Fang B, Roth JA. RNAi-induced synthetic lethality in cancer therapy. Cancer Biol Ther. 2009 Dec; 8(23):2314-6. PMID: 19949302; PMCID: PMC4512945.
      Citations:    Fields:    Translation:HumansAnimalsCells
    229. Meng J, Peng H, Dai B, Guo W, Wang L, Ji L, Minna JD, Chresta CM, Smith PD, Fang B, Roth JA. High level of AKT activity is associated with resistance to MEK inhibitor AZD6244 (ARRY-142886). Cancer Biol Ther. 2009 Nov; 8(21):2073-80. PMID: 19783898; PMCID: PMC2835993.
      Citations: 26     Fields:    Translation:HumansCells
    230. Ivanova AV, Ivanov SV, Prudkin L, Nonaka D, Liu Z, Tsao A, Wistuba I, Roth J, Pass HI. Mechanisms of FUS1/TUSC2 deficiency in mesothelioma and its tumorigenic transcriptional effects. Mol Cancer. 2009 Oct 24; 8:91. PMID: 19852844; PMCID: PMC2776015.
      Citations: 20     Fields:    Translation:HumansCells
    231. Braiteh F, Correa AM, Hofstetter WL, Rice DC, Vaporciyan AA, Walsh GL, Roth JA, Mehran RJ, Swisher SG, Ajani JA. Association of age and survival in patients with gastroesophageal cancer undergoing surgery with or without preoperative therapy. Cancer. 2009 Oct 01; 115(19):4450-8. PMID: 19562780.
      Citations: 3     Fields:    Translation:Humans
    232. Blackmon SH, Shah N, Roth JA, Correa AM, Vaporciyan AA, Rice DC, Hofstetter W, Walsh GL, Benjamin R, Pollock R, Swisher SG, Mehran R. Resection of pulmonary and extrapulmonary sarcomatous metastases is associated with long-term survival. Ann Thorac Surg. 2009 Sep; 88(3):877-84; discussion 884-5. PMID: 19699915.
      Citations: 53     Fields:    Translation:Humans
    233. Du L, Schageman JJ, Subauste MC, Saber B, Hammond SM, Prudkin L, Wistuba II, Ji L, Roth JA, Minna JD, Pertsemlidis A. miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1. Mol Cancer Res. 2009 Aug; 7(8):1234-43. PMID: 19671678; PMCID: PMC2741087.
      Citations: 117     Fields:    Translation:HumansCells
    234. Bolton WD, Rice DC, Correa AM, Hofstetter W, Komaki R, Mehran R, Pisters K, Roth JA, Vaporciyan AA, Walsh GL, Swisher SG. Influence of age on choice of therapy and surgical outcomes in patients with nonsmall cell lung cancer. Am Surg. 2009 Jul; 75(7):598-603; discussion 603-4. PMID: 19655604.
      Citations: 4     Fields:    Translation:Humans
    235. Bolton WD, Rice DC, Goodyear A, Correa AM, Erasmus J, Hofstetter W, Komaki R, Mehran R, Pisters K, Roth JA, Swisher SG, Vaporciyan AA, Walsh GL, Weaver J, Rhines L. Superior sulcus tumors with vertebral body involvement: a multimodality approach. J Thorac Cardiovasc Surg. 2009 Jun; 137(6):1379-87. PMID: 19464452.
      Citations: 8     Fields:    Translation:Humans
    236. Kassis ES, Vaporciyan AA, Swisher SG, Correa AM, Bekele BN, Erasmus JJ, Hofstetter WL, Komaki R, Mehran RJ, Moran CA, Pisters KM, Rice DC, Walsh GL, Roth JA. Application of the revised lung cancer staging system (IASLC Staging Project) to a cancer center population. J Thorac Cardiovasc Surg. 2009 Aug; 138(2):412-418.e1-2. PMID: 19619787; PMCID: PMC2731793.
      Citations: 12     Fields:    Translation:Humans
    237. Bolton WD, Hofstetter WL, Francis AM, Correa AM, Ajani JA, Bhutani MS, Erasmus J, Komaki R, Maru DM, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Swisher SG. Impact of tumor length on long-term survival of pT1 esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2009 Oct; 138(4):831-6. PMID: 19660349.
      Citations: 21     Fields:    Translation:Humans
    238. William WN, Lin HY, Lee JJ, Lippman SM, Roth JA, Kim ES. Revisiting stage IIIB and IV non-small cell lung cancer: analysis of the surveillance, epidemiology, and end results data. Chest. 2009 Sep; 136(3):701-709. PMID: 19318668.
      Citations: 42     Fields:    Translation:Humans
    239. Tsao AS, Wistuba I, Roth JA, Kindler HL. Malignant pleural mesothelioma. J Clin Oncol. 2009 Apr 20; 27(12):2081-90. PMID: 19255316; PMCID: PMC4881753.
      Citations: 113     Fields:    Translation:Humans
    240. Pataer A, Swisher SG, Roth JA, Logothetis CJ, Corn PG. Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity. Cancer Biol Ther. 2009 Feb; 8(3):245-52. PMID: 19106640; PMCID: PMC2854203.
      Citations: 14     Fields:    Translation:HumansCells
    241. Yendamuri S, Swisher SG, Correa AM, Hofstetter W, Ajani JA, Francis A, Maru D, Mehran RJ, Rice DC, Roth JA, Walsh GL, Vaporciyan AA. Esophageal tumor length is independently associated with long-term survival. Cancer. 2009 Feb 01; 115(3):508-16. PMID: 19117343.
      Citations: 26     Fields:    Translation:Humans
    242. Tsao AS, Mehran R, Roth JA. Neoadjuvant and intrapleural therapies for malignant pleural mesothelioma. Clin Lung Cancer. 2009 Jan; 10(1):36-41. PMID: 19289370.
      Citations: 5     Fields:    Translation:Humans
    243. Rice D, Swisher S, Pisters K, Fossella F, Herbst R, Hofstetter W, Kies M, Komaki R, Lippman S, Mehran R, Roth J, Stewart D, Vaporciyan A, Walsh G, Cox J. Comment on "Treatment of non-small cell lung cancer stage IIIA: ACCP evidence-based clinical practice guidelines (2nd edition)". Chest. 2008 Dec; 134(6):1349. PMID: 19059972.
      Citations:    Fields:    Translation:Humans
    244. Chang JY, Balter PA, Dong L, Yang Q, Liao Z, Jeter M, Bucci MK, McAleer MF, Mehran RJ, Roth JA, Komaki R. Stereotactic body radiation therapy in centrally and superiorly located stage I or isolated recurrent non-small-cell lung cancer. Int J Radiat Oncol Biol Phys. 2008 Nov 15; 72(4):967-71. PMID: 18954709; PMCID: PMC5113613.
      Citations: 87     Fields:    Translation:HumansCTClinical Trials
    245. Stanislaus R, Behrens C, Wistuba II, Minna JD, Garner HR, Swisher SG, Roth JA, Correa AM, Broom B, Coombes K, Almeida JS, Deus HF. Data driven semantic integration of translational lung cancer research at MDAnderson Cancer Center. AMIA Annu Symp Proc. 2008 Nov 06; 927. PMID: 18999102.
      Citations:    Fields:    
    246. Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, Larson DE, Chen K, Dooling DJ, Sabo A, Hawes AC, Shen H, Jhangiani SN, Lewis LR, Hall O, Zhu Y, Mathew T, Ren Y, Yao J, Scherer SE, Clerc K, Metcalf GA, Ng B, Milosavljevic A, Gonzalez-Garay ML, Osborne JR, Meyer R, Shi X, Tang Y, Koboldt DC, Lin L, Abbott R, Miner TL, Pohl C, Fewell G, Haipek C, Schmidt H, Dunford-Shore BH, Kraja A, Crosby SD, Sawyer CS, Vickery T, Sander S, Robinson J, Winckler W, Baldwin J, Chirieac LR, Dutt A, Fennell T, Hanna M, Johnson BE, Onofrio RC, Thomas RK, Tonon G, Weir BA, Zhao X, Ziaugra L, Zody MC, Giordano T, Orringer MB, Roth JA, Spitz MR, Wistuba II, Ozenberger B, Good PJ, Chang AC, Beer DG, Watson MA, Ladanyi M, Broderick S, Yoshizawa A, Travis WD, Pao W, Province MA, Weinstock GM, Varmus HE, Gabriel SB, Lander ES, Gibbs RA, Meyerson M, Wilson RK. Somatic mutations affect key pathways in lung adenocarcinoma. Nature. 2008 Oct 23; 455(7216):1069-75. PMID: 18948947; PMCID: PMC2694412.
      Citations: 1312     Fields:    Translation:Humans
    247. Shivapurkar N, Stastny V, Okumura N, Girard L, Xie Y, Prinsen C, Thunnissen FB, Wistuba II, Czerniak B, Frenkel E, Roth JA, Liloglou T, Xinarianos G, Field JK, Minna JD, Gazdar AF. Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene. Cancer Res. 2008 Sep 15; 68(18):7448-56. PMID: 18794132; PMCID: PMC2849650.
      Citations: 48     Fields:    Translation:HumansCells
    248. Yendamuri S, Vaporciyan AA, Zaidi T, Feng L, Fernandez R, Bekele NB, Hofstetter WL, Jiang F, Mehran RJ, Rice DC, Spitz MR, Swisher SG, Walsh GL, Roth JA, Katz RL. 3p22.1 and 10q22.3 deletions detected by fluorescence in situ hybridization (FISH): a potential new tool for early detection of non-small cell lung Cancer (NSCLC). J Thorac Oncol. 2008 Sep; 3(9):979-84. PMID: 18758299; PMCID: PMC3370669.
      Citations: 9     Fields:    Translation:HumansCells
    249. Deus HF, Stanislaus R, Veiga DF, Behrens C, Wistuba II, Minna JD, Garner HR, Swisher SG, Roth JA, Correa AM, Broom B, Coombes K, Chang A, Vogel LH, Almeida JS. A Semantic Web management model for integrative biomedical informatics. PLoS One. 2008 Aug 13; 3(8):e2946. PMID: 18698353; PMCID: PMC2491554.
      Citations: 12     Fields:    
    250. Pataer A, Hu W, Xiaolin L, Chada S, Roth JA, Hunt KK, Swisher SG. Adenoviral endoplasmic reticulum-targeted mda-7/interleukin-24 vector enhances human cancer cell killing. Mol Cancer Ther. 2008 Aug; 7(8):2528-35. PMID: 18723497; PMCID: PMC2597048.
      Citations: 10     Fields:    Translation:AnimalsCells
    251. Katz RL, Zaidi TM, Fernandez RL, Zhang J, He W, Acosta C, Daniely M, Madi L, Vargas MA, Dong Q, Gao X, Jiang XG, Jiang F, Caraway NP, Vaporciyan AA, Roth JA, Spitz MR. Automated detection of genetic abnormalities combined with cytology in sputum is a sensitive predictor of lung cancer. Mod Pathol. 2008 Aug; 21(8):950-60. PMID: 18500269; PMCID: PMC3377448.
      Citations: 20     Fields:    Translation:HumansCellsCTClinical Trials
    252. Roth JA. Gene therapy in thoracic oncology. Ann Thorac Surg. 2008 May; 85(5):1837-8. PMID: 18446981.
      Citations: 1     Fields:    Translation:Humans
    253. Ji L, Roth JA. Tumor suppressor FUS1 signaling pathway. J Thorac Oncol. 2008 Apr; 3(4):327-30. PMID: 18379348; PMCID: PMC3370667.
      Citations: 40     Fields:    Translation:HumansCells
    254. Prudkin L, Behrens C, Liu DD, Zhou X, Ozburn NC, Bekele BN, Minna JD, Moran C, Roth JA, Ji L, Wistuba II. Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer. Clin Cancer Res. 2008 Jan 01; 14(1):41-7. PMID: 18172250; PMCID: PMC2833352.
      Citations: 43     Fields:    Translation:Humans
    255. Chada S, Menander KB, Bocangel D, Roth JA, Ramesh R. Cancer targeting using tumor suppressor genes. Front Biosci. 2008 Jan 01; 13:1959-67. PMID: 17981683.
      Citations: 5     Fields:    Translation:HumansAnimals
    256. Weir BA, Woo MS, Getz G, Perner S, Ding L, Beroukhim R, Lin WM, Province MA, Kraja A, Johnson LA, Shah K, Sato M, Thomas RK, Barletta JA, Borecki IB, Broderick S, Chang AC, Chiang DY, Chirieac LR, Cho J, Fujii Y, Gazdar AF, Giordano T, Greulich H, Hanna M, Johnson BE, Kris MG, Lash A, Lin L, Lindeman N, Mardis ER, McPherson JD, Minna JD, Morgan MB, Nadel M, Orringer MB, Osborne JR, Ozenberger B, Ramos AH, Robinson J, Roth JA, Rusch V, Sasaki H, Shepherd F, Sougnez C, Spitz MR, Tsao MS, Twomey D, Verhaak RG, Weinstock GM, Wheeler DA, Winckler W, Yoshizawa A, Yu S, Zakowski MF, Zhang Q, Beer DG, Wistuba II, Watson MA, Garraway LA, Ladanyi M, Travis WD, Pao W, Rubin MA, Gabriel SB, Gibbs RA, Varmus HE, Wilson RK, Lander ES, Meyerson M. Characterizing the cancer genome in lung adenocarcinoma. Nature. 2007 Dec 06; 450(7171):893-8. PMID: 17982442; PMCID: PMC2538683.
      Citations: 549     Fields:    Translation:HumansCells
    257. Jayachandran G, Sazaki J, Nishizaki M, Xu K, Girard L, Minna JD, Roth JA, Ji L. Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch. Cancer Res. 2007 Nov 01; 67(21):10379-88. PMID: 17974981.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    258. Yendamuri S, Komaki RR, Correa AM, Allen P, Wynn B, Blackmon S, Hofstetter WL, Rice DC, Roth JA, Swisher SG, Vaporciyan AA, Walsh GL, Mehran RJ. Comparison of limited surgery and three-dimensional conformal radiation in high-risk patients with stage I non-small cell lung cancer. J Thorac Oncol. 2007 Nov; 2(11):1022-8. PMID: 17975494.
      Citations: 6     Fields:    Translation:Humans
    259. Rice DC, Stevens CW, Correa AM, Vaporciyan AA, Tsao A, Forster KM, Walsh GL, Swisher SG, Hofstetter WL, Mehran RJ, Roth JA, Liao Z, Smythe WR. Outcomes after extrapleural pneumonectomy and intensity-modulated radiation therapy for malignant pleural mesothelioma. Ann Thorac Surg. 2007 Nov; 84(5):1685-92; discussion 1692-3. PMID: 17954086.
      Citations: 58     Fields:    Translation:Humans
    260. Hittelman WN, Liu DD, Kurie JM, Lotan R, Lee JS, Khuri F, Ibarguen H, Morice RC, Walsh G, Roth JA, Minna J, Ro JY, Broxson A, Hong WK, Lee JJ. Proliferative changes in the bronchial epithelium of former smokers treated with retinoids. J Natl Cancer Inst. 2007 Nov 07; 99(21):1603-12. PMID: 17971525; PMCID: PMC3441140.
      Citations: 10     Fields:    Translation:Humans
    261. von Holzen U, Pataer A, Raju U, Bocangel D, Vorburger SA, Liu Y, Lu X, Roth JA, Aggarwal BB, Barber GN, Keyomarsi K, Hunt KK, Swisher SG. The double-stranded RNA-activated protein kinase mediates radiation resistance in mouse embryo fibroblasts through nuclear factor kappaB and Akt activation. Clin Cancer Res. 2007 Oct 15; 13(20):6032-9. PMID: 17947465.
      Citations: 12     Fields:    Translation:AnimalsCells
    262. Pataer A, Chada S, Roth JA, Hunt KK, Swisher SG. Development of Ad-mda7/IL-24-resistant lung cancer cell lines. Cancer Biol Ther. 2008 Jan; 7(1):103-8. PMID: 18059175; PMCID: PMC3442784.
      Citations: 2     Fields:    Translation:HumansCells
    263. Bakaeen F, Rice D, Correa AM, Walsh GL, Vaporciyan AA, Putnam JB, Swisher SG, Roth JA, Huh J, Chu D, Smythe WR. Use of aprotinin in extrapleural pneumonectomy: effect on hemostasis and incidence of complications. Ann Thorac Surg. 2007 Sep; 84(3):982-6. PMID: 17720413.
      Citations: 1     Fields:    Translation:Humans
    264. Martin LW, Correa AM, Ordonez NG, Roth JA, Swisher SG, Vaporciyan AA, Walsh GL, Rice DC. Sarcomatoid carcinoma of the lung: a predictor of poor prognosis. Ann Thorac Surg. 2007 Sep; 84(3):973-80. PMID: 17720411.
      Citations: 47     Fields:    Translation:Humans
    265. Roth JA. Treatment of esophageal cancer: does surgery make the cut? Gastrointest Cancer Res. 2007 Sep; 1(5):207-8. PMID: 19262711; PMCID: PMC2632533.
      Citations:    
    266. Kelsen DP, Winter KA, Gunderson LL, Mortimer J, Estes NC, Haller DG, Ajani JA, Kocha W, Minsky BD, Roth JA, Willett CG, Radiation Therapy Oncology Group, USA Intergroup. Long-term results of RTOG trial 8911 (USA Intergroup 113): a random assignment trial comparison of chemotherapy followed by surgery compared with surgery alone for esophageal cancer. J Clin Oncol. 2007 Aug 20; 25(24):3719-25. PMID: 17704421.
      Citations: 181     Fields:    Translation:Humans
    267. Hofstetter W, Correa AM, Bekele N, Ajani JA, Phan A, Komaki RR, Liao Z, Maru D, Wu TT, Mehran RJ, Rice DC, Roth JA, Vaporciyan AA, Walsh GL, Francis A, Blackmon S, Swisher SG. Proposed modification of nodal status in AJCC esophageal cancer staging system. Ann Thorac Surg. 2007 Aug; 84(2):365-73; discussion 374-5. PMID: 17643602.
      Citations: 28     Fields:    Translation:Humans
    268. Deng WG, Jayachandran G, Wu G, Xu K, Roth JA, Ji L. Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancer-binding protein-2beta in human lung cancer cells. J Biol Chem. 2007 Sep 07; 282(36):26460-70. PMID: 17630431.
      Citations: 30     Fields:    Translation:HumansCells
    269. Ohtani S, Iwamaru A, Deng W, Ueda K, Wu G, Jayachandran G, Kondo S, Atkinson EN, Minna JD, Roth JA, Ji L. Tumor suppressor 101F6 and ascorbate synergistically and selectively inhibit non-small cell lung cancer growth by caspase-independent apoptosis and autophagy. Cancer Res. 2007 Jul 01; 67(13):6293-303. PMID: 17616688.
      Citations: 23     Fields:    Translation:HumansCells
    270. Elayadi AN, Samli KN, Prudkin L, Liu YH, Bian A, Xie XJ, Wistuba II, Roth JA, McGuire MJ, Brown KC. A peptide selected by biopanning identifies the integrin alphavbeta6 as a prognostic biomarker for nonsmall cell lung cancer. Cancer Res. 2007 Jun 15; 67(12):5889-95. PMID: 17575158.
      Citations: 80     Fields:    Translation:HumansCells
    271. Chang JY, Roth JA. Stereotactic body radiation therapy for stage I non-small cell lung cancer. Thorac Surg Clin. 2007 May; 17(2):251-9. PMID: 17626403.
      Citations: 16     Fields:    Translation:Humans
    272. Blackmon SH, Correa AM, Wynn B, Hofstetter WL, Martin LW, Mehran RJ, Rice DC, Swisher SG, Walsh GL, Roth JA, Vaporciyan AA. Propensity-matched analysis of three techniques for intrathoracic esophagogastric anastomosis. Ann Thorac Surg. 2007 May; 83(5):1805-13; discussion 1813. PMID: 17462404.
      Citations: 38     Fields:    Translation:Humans
    273. Deng WG, Nishizaki M, Fang B, Roth JA, Ji L. Induction of apoptosis by tumor suppressor FHIT via death receptor signaling pathway in human lung cancer cells. Biochem Biophys Res Commun. 2007 Apr 20; 355(4):993-9. PMID: 17328863; PMCID: PMC1934611.
      Citations: 9     Fields:    Translation:HumansCells
    274. Deng WG, Kawashima H, Wu G, Jayachandran G, Xu K, Minna JD, Roth JA, Ji L. Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells. Cancer Res. 2007 Jan 15; 67(2):709-17. PMID: 17234782.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    275. Gu J, Berman D, Lu C, Wistuba II, Roth JA, Frazier M, Spitz MR, Wu X. Aberrant promoter methylation profile and association with survival in patients with non-small cell lung cancer. Clin Cancer Res. 2006 Dec 15; 12(24):7329-38. PMID: 17189404.
      Citations: 34     Fields:    Translation:HumansCells
    276. Herrera LJ, Correa AM, Vaporciyan AA, Hofstetter WL, Rice DC, Swisher SG, Walsh GL, Roth JA, Mehran RJ. Increased risk of aspiration and pulmonary complications after lung resection in head and neck cancer patients. Ann Thorac Surg. 2006 Dec; 82(6):1982-7; discussion 1987-8. PMID: 17126095.
      Citations: 3     Fields:    Translation:Humans
    277. Ueda K, Kawashima H, Ohtani S, Deng WG, Ravoori M, Bankson J, Gao B, Girard L, Minna JD, Roth JA, Kundra V, Ji L. The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells. Cancer Res. 2006 Oct 01; 66(19):9682-90. PMID: 17018626.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    278. Hamada K, Shirakawa T, Gotoh A, Roth JA, Follen M. Adenovirus-mediated transfer of human papillomavirus 16 E6/E7 antisense RNA and induction of apoptosis in cervical cancer. Gynecol Oncol. 2006 Dec; 103(3):820-30. PMID: 16908054.
      Citations: 7     Fields:    Translation:HumansCells
    279. Malaisrie SC, Hofstetter WL, Correa AM, Ajani JA, Komaki RR, Rice DC, Vaporciyan AA, Walsh GL, Roth JA, Wu TT, Swisher SG. The addition of induction chemotherapy to preoperative, concurrent chemoradiotherapy improves tumor response in patients with esophageal adenocarcinoma. Cancer. 2006 Sep 01; 107(5):967-74. PMID: 16874819.
      Citations: 10     Fields:    Translation:Humans
    280. Peng HH, Wu S, Davis JJ, Wang L, Roth JA, Marini FC, Fang B. A rapid and efficient method for purification of recombinant adenovirus with arginine-glycine-aspartic acid-modified fibers. Anal Biochem. 2006 Jul 01; 354(1):140-7. PMID: 16707084; PMCID: PMC1475777.
      Citations: 20     Fields:    Translation:HumansCells
    281. Ajani J, Bekaii-Saab T, D'Amico TA, Fuchs C, Gibson MK, Goldberg M, Hayman JA, Ilson DH, Javle M, Kelley S, Kurtz RC, Locker GY, Meropol NJ, Minsky BD, Orringer MB, Osarogiagbon RU, Posey JA, Roth J, Sasson AR, Swisher SG, Wood DE, Yen Y. Esophageal Cancer Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr; 4(4):328-47. PMID: 16569387.
      Citations: 5     Fields:    Translation:Humans
    282. Ajani J, Bekaii-Saab T, D'Amico TA, Fuchs C, Gibson MK, Goldberg M, Hayman JA, Ilson DH, Javle M, Kelley S, Kurtz RC, Locker GY, Meropol NJ, Minsky BD, Orringer MB, Osarogiagbon RU, Posey JA, Roth J, Sasson AR, Swisher SG, Wood DE, Yen Y. Gastric Cancer Clinical Practice Guidelines. J Natl Compr Canc Netw. 2006 Apr; 4(4):350-66. PMID: 16569388.
      Citations: 11     Fields:    Translation:Humans
    283. Tsao AS, Tang XM, Sabloff B, Xiao L, Shigematsu H, Roth J, Spitz M, Hong WK, Gazdar A, Wistuba I. Clinicopathologic characteristics of the EGFR gene mutation in non-small cell lung cancer. J Thorac Oncol. 2006 Mar; 1(3):231-9. PMID: 17409862.
      Citations: 56     Fields:    Translation:Humans
    284. Rohatgi PR, Swisher SG, Correa AM, Wu TT, Liao Z, Komaki R, Walsh GL, Vaporciyan AA, Rice DC, Bresalier RS, Roth JA, Ajani JA. Histologic subtypes as determinants of outcome in esophageal carcinoma patients with pathologic complete response after preoperative chemoradiotherapy. Cancer. 2006 Feb 01; 106(3):552-8. PMID: 16353210.
      Citations: 20     Fields:    Translation:Humans
    285. Martin LW, Hofstetter W, Swisher SG, Roth JA. Management of intrathoracic leaks following esophagectomy. Adv Surg. 2006; 40:173-90. PMID: 17163101.
      Citations: 8     Fields:    Translation:Humans
    286. Roth JA. Adenovirus p53 gene therapy. Expert Opin Biol Ther. 2006 Jan; 6(1):55-61. PMID: 16370914.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    287. Malaisrie SC, Hofstetter WL, Correa AM, Ajani JA, Komaki RR, Liao Z, Phan A, Rice DC, Vaporciyan AA, Walsh GL, Lahoti S, Lee JH, Bresalier R, Roth JA, Swisher SG. Endoscopic ultrasonography-identified celiac adenopathy remains a poor prognostic factor despite preoperative chemoradiotherapy in esophageal adenocarcinoma. J Thorac Cardiovasc Surg. 2006 Jan; 131(1):65-72. PMID: 16399296.
      Citations: 1     Fields:    Translation:Humans
    288. Rohatgi P, Swisher SG, Correa AM, Wu TT, Liao Z, Komaki R, Walsh GL, Vaporciyan AA, Rice DC, Roth JA, Ajani JA. Characterization of pathologic complete response after preoperative chemoradiotherapy in carcinoma of the esophagus and outcome after pathologic complete response. Cancer. 2005 Dec 01; 104(11):2365-72. PMID: 16245310.
      Citations: 39     Fields:    Translation:Humans
    289. Martin LW, Correa AM, Hofstetter W, Hong WK, Komaki R, Putnam JB, Rice DC, Smythe WR, Swisher SG, Vaporciyan AA, Walsh GL, Roth JA. The evolution of treatment outcomes for resected stage IIIA non-small cell lung cancer over 16 years at a single institution. J Thorac Cardiovasc Surg. 2005 Dec; 130(6):1601-10. PMID: 16308005.
      Citations: 2     Fields:    Translation:Humans
    290. Liao Z, Liu H, Swisher SG, Wang L, Wu TT, Correa AM, Roth JA, Cox JD, Komaki R, Ajani JA, Wei Q. Polymorphism at the 3'-UTR of the thymidylate synthase gene: a potential predictor for outcomes in Caucasian patients with esophageal adenocarcinoma treated with preoperative chemoradiation. Int J Radiat Oncol Biol Phys. 2006 Mar 01; 64(3):700-8. PMID: 16242255.
      Citations: 3     Fields:    Translation:Humans
    291. Ascioti AJ, Hofstetter WL, Miller MJ, Rice DC, Swisher SG, Vaporciyan AA, Roth JA, Putnam JB, Smythe WR, Feig BW, Mansfield PF, Pisters PW, Torres MT, Walsh GL. Long-segment, supercharged, pedicled jejunal flap for total esophageal reconstruction. J Thorac Cardiovasc Surg. 2005 Nov; 130(5):1391-8. PMID: 16256794.
      Citations: 14     Fields:    Translation:Humans
    292. Hamada K, Sakaue M, Sarkar A, Buchl S, Satterfield W, Keeling M, Sastry J, Roth JA, Follen M. Immune responses to repetitive adenovirus-mediated gene transfer and restoration of gene expression by cyclophosphamide or etoposide. Gynecol Oncol. 2005 Dec; 99(3 Suppl 1):S177-86. PMID: 16214207.
      Citations: 1     Fields:    Translation:AnimalsCells
    293. Feith M, Bruecher BL, Naehrig J, Sarbia M, Siewert JR, Stein HJ. Early esophageal cancer: pattern of lymphatic spread and prognostic factors for long-term survival after surgical resection. Ann Surg. 2005 Oct; 242(4):566-73; discussion 573-5. PMID: 16192817; PMCID: PMC1402356.
      Citations: 140     Fields:    Translation:Humans
    294. Rohatgi PR, Swisher SG, Correa AM, Wu TT, Liao Z, Komaki R, Walsh G, Vaporciyan A, Lynch PM, Rice DC, Roth JA, Ajani JA. Failure patterns correlate with the proportion of residual carcinoma after preoperative chemoradiotherapy for carcinoma of the esophagus. Cancer. 2005 Oct 01; 104(7):1349-55. PMID: 16130133.
      Citations: 43     Fields:    Translation:Humans
    295. Hamada K, Ueda N, Ito M, Roth JA, Follen M. The nude rat as an orthotopic model for cervical cancer. Gynecol Oncol. 2005 Dec; 99(3 Suppl 1):S159-65. PMID: 16185752.
      Citations:    Fields:    Translation:HumansAnimalsCells
    296. Martin LW, Swisher SG, Hofstetter W, Correa AM, Mehran RJ, Rice DC, Vaporciyan AA, Walsh GL, Roth JA. Intrathoracic leaks following esophagectomy are no longer associated with increased mortality. Ann Surg. 2005 Sep; 242(3):392-9; discussion 399-402. PMID: 16135925; PMCID: PMC1357747.
      Citations: 35     Fields:    Translation:Humans
    297. Tang X, Shigematsu H, Bekele BN, Roth JA, Minna JD, Hong WK, Gazdar AF, Wistuba II. EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients. Cancer Res. 2005 Sep 01; 65(17):7568-72. PMID: 16140919.
      Citations: 88     Fields:    Translation:HumansCells
    298. Pataer A, Vorburger SA, Chada S, Balachandran S, Barber GN, Roth JA, Hunt KK, Swisher SG. Melanoma differentiation-associated gene-7 protein physically associates with the double-stranded RNA-activated protein kinase PKR. Mol Ther. 2005 May; 11(5):717-23. PMID: 15851010.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    299. Swisher SG, Hofstetter W, Wu TT, Correa AM, Ajani JA, Komaki RR, Chirieac L, Hunt KK, Liao Z, Phan A, Rice DC, Vaporciyan AA, Walsh GL, Roth JA. Proposed revision of the esophageal cancer staging system to accommodate pathologic response (pP) following preoperative chemoradiation (CRT). Ann Surg. 2005 May; 241(5):810-7; discussion 817-20. PMID: 15849517; PMCID: PMC1357136.
      Citations: 58     Fields:    Translation:Humans
    300. Agarwal B, Swisher SG, Ajani J, Kelly K, Komaki RR, Abu-Hamda E, Correa AM, Roth JA. Differential response to preoperative chemoradiation and surgery in esophageal adenocarcinomas based on presence of Barrett's esophagus and symptomatic gastroesophageal reflux. Ann Thorac Surg. 2005 May; 79(5):1716-23. PMID: 15854962.
      Citations: 3     Fields:    Translation:Humans
    301. Chirieac LR, Swisher SG, Ajani JA, Komaki RR, Correa AM, Morris JS, Roth JA, Rashid A, Hamilton SR, Wu TT. Posttherapy pathologic stage predicts survival in patients with esophageal carcinoma receiving preoperative chemoradiation. Cancer. 2005 Apr 01; 103(7):1347-55. PMID: 15719440.
      Citations: 137     Fields:    Translation:Humans
    302. Shigematsu H, Lin L, Takahashi T, Nomura M, Suzuki M, Wistuba II, Fong KM, Lee H, Toyooka S, Shimizu N, Fujisawa T, Feng Z, Roth JA, Herz J, Minna JD, Gazdar AF. Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers. J Natl Cancer Inst. 2005 Mar 02; 97(5):339-46. PMID: 15741570.
      Citations: 794     Fields:    Translation:HumansCells
    303. Saito Y, Miyahara R, Gopalan B, Litvak A, Inoue S, Shanker M, Branch CD, Mhashilkar AM, Roth JA, Chada S, Ramesh R. Selective induction of cell cycle arrest and apoptosis in human prostate cancer cells through adenoviral transfer of the melanoma differentiation-associated -7 (mda-7)/interleukin-24 (IL-24) gene. Cancer Gene Ther. 2005 Mar; 12(3):238-47. PMID: 15578066.
      Citations: 13     Fields:    Translation:HumansCells
    304. Sasaki R, Komaki R, Macapinlac H, Erasmus J, Allen P, Forster K, Putnam JB, Herbst RS, Moran CA, Podoloff DA, Roth JA, Cox JD. [18F]fluorodeoxyglucose uptake by positron emission tomography predicts outcome of non-small-cell lung cancer. J Clin Oncol. 2005 Feb 20; 23(6):1136-43. PMID: 15718309.
      Citations: 81     Fields:    Translation:Humans
    305. Ji L, Minna JD, Roth JA. 3p21.3 tumor suppressor cluster: prospects for translational applications. Future Oncol. 2005 Feb; 1(1):79-92. PMID: 16555978.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    306. Rice DC, Correa AM, Vaporciyan AA, Sodhi N, Smythe WR, Swisher SG, Walsh GL, Putnam JB, Komaki R, Ajani JA, Roth JA. Preoperative chemoradiotherapy prior to esophagectomy in elderly patients is not associated with increased morbidity. Ann Thorac Surg. 2005 Feb; 79(2):391-7; discussionn 391-7. PMID: 15680801.
      Citations: 13     Fields:    Translation:Humans
    307. Oida Y, Gopalan B, Miyahara R, Inoue S, Branch CD, Mhashilkar AM, Lin E, Bekele BN, Roth JA, Chada S, Ramesh R. Sulindac enhances adenoviral vector expressing mda-7/IL-24-mediated apoptosis in human lung cancer. Mol Cancer Ther. 2005 Feb; 4(2):291-304. PMID: 15713900.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    308. Wu X, Roth JA, Zhao H, Luo S, Zheng YL, Chiang S, Spitz MR. Cell cycle checkpoints, DNA damage/repair, and lung cancer risk. Cancer Res. 2005 Jan 01; 65(1):349-57. PMID: 15665313.
      Citations: 11     Fields:    Translation:HumansCells
    309. Rohatgi PR, Swisher SG, Correa AM, Wu TT, Liao Z, Walsh GL, Vaporciyan AA, Rice DC, Fukami N, Roth JA, Ajani JA. Comparison of clinical stage, therapy response, and patient outcome between squamous cell carcinoma and adenocarcinoma of the esophagus. Int J Gastrointest Cancer. 2005; 36(2):69-76. PMID: 16648656.
      Citations: 5     Fields:    Translation:Humans
    310. Ramesh R, Ito I, Saito Y, Wu Z, Mhashikar AM, Wilson DR, Branch CD, Roth JA, Chada S. Local and systemic inhibition of lung tumor growth after nanoparticle-mediated mda-7/IL-24 gene delivery. DNA Cell Biol. 2004 Dec; 23(12):850-7. PMID: 15684712.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    311. Liao Z, Zhang Z, Jin J, Ajani JA, Swisher SG, Stevens CW, Ho L, Smythe R, Vaporciyan AA, Putnam JB, Walsh GL, Roth JA, Yao JC, Allen PK, Cox JD, Komaki R. Esophagectomy after concurrent chemoradiotherapy improves locoregional control in clinical stage II or III esophageal cancer patients. Int J Radiat Oncol Biol Phys. 2004 Dec 01; 60(5):1484-93. PMID: 15590179.
      Citations: 12     Fields:    Translation:Humans
    312. Gopalan B, Ito I, Branch CD, Stephens C, Roth JA, Ramesh R. Nanoparticle based systemic gene therapy for lung cancer: molecular mechanisms and strategies to suppress nanoparticle-mediated inflammatory response. Technol Cancer Res Treat. 2004 Dec; 3(6):647-57. PMID: 15560723.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    313. Ito I, Ji L, Tanaka F, Saito Y, Gopalan B, Branch CD, Xu K, Atkinson EN, Bekele BN, Stephens LC, Minna JD, Roth JA, Ramesh R. Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo. Cancer Gene Ther. 2004 Nov; 11(11):733-9. PMID: 15486560.
      Citations: 41     Fields:    Translation:HumansCells
    314. Swisher SG, Erasmus J, Maish M, Correa AM, Macapinlac H, Ajani JA, Cox JD, Komaki RR, Hong D, Lee HK, Putnam JB, Rice DC, Smythe WR, Thai L, Vaporciyan AA, Walsh GL, Wu TT, Roth JA. 2-Fluoro-2-deoxy-D-glucose positron emission tomography imaging is predictive of pathologic response and survival after preoperative chemoradiation in patients with esophageal carcinoma. Cancer. 2004 Oct 15; 101(8):1776-85. PMID: 15386332.
      Citations: 72     Fields:    Translation:Humans
    315. Swisher SG, Maish M, Erasmus JJ, Correa AM, Ajani JA, Bresalier R, Komaki R, Macapinlac H, Munden RF, Putnam JB, Rice D, Smythe WR, Vaporciyan AA, Walsh GL, Wu TT, Roth JA. Utility of PET, CT, and EUS to identify pathologic responders in esophageal cancer. Ann Thorac Surg. 2004 Oct; 78(4):1152-60; discussion 1152-60. PMID: 15464463.
      Citations: 83     Fields:    Translation:Humans
    316. Jin J, Liao Z, Zhang Z, Ajani J, Swisher S, Chang JY, Jeter M, Guerrero T, Stevens CW, Vaporciyan A, Putnam J, Walsh G, Smythe R, Roth J, Yao J, Allen P, Cox JD, Komaki R. Induction chemotherapy improved outcomes of patients with resectable esophageal cancer who received chemoradiotherapy followed by surgery. Int J Radiat Oncol Biol Phys. 2004 Oct 01; 60(2):427-36. PMID: 15380576.
      Citations: 16     Fields:    Translation:Humans
    317. Gomyo Y, Sasaki J, Branch C, Roth JA, Mukhopadhyay T. 5-aza-2'-deoxycytidine upregulates caspase-9 expression cooperating with p53-induced apoptosis in human lung cancer cells. Oncogene. 2004 Sep 02; 23(40):6779-87. PMID: 15273730.
      Citations: 30     Fields:    Translation:HumansCells
    318. Nishizaki M, Sasaki J, Fang B, Atkinson EN, Minna JD, Roth JA, Ji L. Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells. Cancer Res. 2004 Aug 15; 64(16):5745-52. PMID: 15313915.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    319. Agarwal B, Swisher S, Ajani J, Kelly K, Fanning C, Komaki RR, Putnam JB, Abu-Hamda E, Molke KL, Walsh GL, Correa AM, Ho L, Liao Z, Lynch PM, Rice DC, Smythe WR, Stevens CW, Vaporciyan AA, Yao J, Roth JA. Endoscopic ultrasound after preoperative chemoradiation can help identify patients who benefit maximally after surgical esophageal resection. Am J Gastroenterol. 2004 Jul; 99(7):1258-66. PMID: 15233663.
      Citations: 7     Fields:    Translation:Humans
    320. Ajani JA, Walsh G, Komaki R, Morris J, Swisher SG, Putnam JB, Lynch PM, Wu TT, Smythe R, Vaporciyan A, Faust J, Cohen DS, Nivers R, Roth JA. Preoperative induction of CPT-11 and cisplatin chemotherapy followed by chemoradiotherapy in patients with locoregional carcinoma of the esophagus or gastroesophageal junction. Cancer. 2004 Jun 01; 100(11):2347-54. PMID: 15160337.
      Citations: 19     Fields:    Translation:Humans
    321. Chada S, Sutton RB, Ekmekcioglu S, Ellerhorst J, Mumm JB, Leitner WW, Yang HY, Sahin AA, Hunt KK, Fuson KL, Roth JA, Ramesh R, Grimm EA, Mhashilkar AM, Po?ndexter N. MDA-7/IL-24 is a unique cytokine--tumor suppressor in the IL-10 family. Int Immunopharmacol. 2004 May; 4(5):649-67. PMID: 15120650.
      Citations: 39     Fields:    Translation:Humans
    322. Uno F, Sasaki J, Nishizaki M, Carboni G, Xu K, Atkinson EN, Kondo M, Minna JD, Roth JA, Ji L. Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells. Cancer Res. 2004 May 01; 64(9):2969-76. PMID: 15126327.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    323. Honda T, Coppola S, Ghibelli L, Cho SH, Kagawa S, Spurgers KB, Brisbay SM, Roth JA, Meyn RE, Fang B, McDonnell TJ. GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells. Cancer Gene Ther. 2004 Apr; 11(4):249-55. PMID: 15002033.
      Citations: 14     Fields:    Translation:HumansCells
    324. Ito I, Saeki T, Mohuiddin I, Saito Y, Branch CD, Vaporciyan A, Roth JA, Ramesh R. Persistent transgene expression following intravenous administration of a liposomal complex: role of interleukin-10-mediated immune suppression. Mol Ther. 2004 Mar; 9(3):318-27. PMID: 15006598.
      Citations: 2     Fields:    Translation:AnimalsCells
    325. Vaporciyan AA, Correa AM, Rice DC, Roth JA, Smythe WR, Swisher SG, Walsh GL, Putnam JB. Risk factors associated with atrial fibrillation after noncardiac thoracic surgery: analysis of 2588 patients. J Thorac Cardiovasc Surg. 2004 Mar; 127(3):779-86. PMID: 15001907.
      Citations: 80     Fields:    Translation:Humans
    326. Gu J, Zhang L, Swisher SG, Liu J, Roth JA, Fang B. Induction of p53-regulated genes in lung cancer cells: implications of the mechanism for adenoviral p53-mediated apoptosis. Oncogene. 2004 Feb 12; 23(6):1300-7. PMID: 14676844.
      Citations: 7     Fields:    Translation:HumansCells
    327. Roth JA, Grammer SF. Gene replacement therapy for non-small cell lung cancer: a review. Hematol Oncol Clin North Am. 2004 Feb; 18(1):215-29. PMID: 15005290.
      Citations: 5     Fields:    Translation:Humans
    328. Ohtani S, Kagawa S, Tango Y, Umeoka T, Tokunaga N, Tsunemitsu Y, Roth JA, Taya Y, Tanaka N, Fujiwara T. Quantitative analysis of p53-targeted gene expression and visualization of p53 transcriptional activity following intratumoral administration of adenoviral p53 in vivo. Mol Cancer Ther. 2004 Jan; 3(1):93-100. PMID: 14749479.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    329. Taylor NA, Liao ZX, Cox JD, Stevens C, Roth J, Walsh G, Chang JY, Guerrero T, Jeter M, Putnam J, Fossella FV, Allen P, Komaki R. Equivalent outcome of patients with clinical Stage IIIA non-small-cell lung cancer treated with concurrent chemoradiation compared with induction chemotherapy followed by surgical resection. Int J Radiat Oncol Biol Phys. 2004 Jan 01; 58(1):204-12. PMID: 14697440.
      Citations: 13     Fields:    Translation:Humans
    330. Lee HK, Vaporciyan AA, Cox JD, Tucker SL, Putnam JB, Ajani JA, Liao Z, Swisher SG, Roth JA, Smythe WR, Walsh GL, Mohan R, Liu HH, Mooring D, Komaki R. Postoperative pulmonary complications after preoperative chemoradiation for esophageal carcinoma: correlation with pulmonary dose-volume histogram parameters. Int J Radiat Oncol Biol Phys. 2003 Dec 01; 57(5):1317-22. PMID: 14630268.
      Citations: 44     Fields:    Translation:HumansPHPublic Health
    331. Virmani A, Rathi A, Heda S, Sugio K, Lewis C, Tonk V, Takahashi T, Roth JA, Minna JD, Euhus DM, Gazdar AF. Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers. Int J Cancer. 2003 Nov 10; 107(3):341-5. PMID: 14506731.
      Citations: 15     Fields:    Translation:HumansCells
    332. Saito Y, Gopalan B, Mhashilkar AM, Roth JA, Chada S, Zumstein L, Ramesh R. Adenovirus-mediated PTEN treatment combined with caffeine produces a synergistic therapeutic effect in colorectal cancer cells. Cancer Gene Ther. 2003 Nov; 10(11):803-13. PMID: 14605666.
      Citations: 11     Fields:    Translation:HumansCells
    333. Moon C, Oh Y, Roth JA. Current status of gene therapy for lung cancer and head and neck cancer. Clin Cancer Res. 2003 Nov 01; 9(14):5055-67. PMID: 14613982.
      Citations: 20     Fields:    Translation:HumansAnimals
    334. Sah NK, Munshi A, Nishikawa T, Mukhopadhyay T, Roth JA, Meyn RE. Adenovirus-mediated wild-type p53 radiosensitizes human tumor cells by suppressing DNA repair capacity. Mol Cancer Ther. 2003 Nov; 2(11):1223-31. PMID: 14617796.
      Citations: 7     Fields:    Translation:HumansCells
    335. Fang B, Roth JA. The role of gene therapy in combined modality treatment strategies for cancer. Curr Opin Mol Ther. 2003 Oct; 5(5):475-82. PMID: 14601515.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    336. Rice D, Kim HW, Sabichi A, Lippman S, Lee JJ, Williams B, Vaporciyan A, Smythe WR, Swisher S, Walsh G, Putnam JB, Hong WK, Roth J. The risk of second primary tumors after resection of stage I nonsmall cell lung cancer. Ann Thorac Surg. 2003 Oct; 76(4):1001-7; discussion 1007-8. PMID: 14529975.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    337. Lin T, Zhang L, Davis J, Gu J, Nishizaki M, Ji L, Roth JA, Xiong M, Fang B. Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers. Mol Ther. 2003 Sep; 8(3):441-8. PMID: 12946317.
      Citations: 14     Fields:    Translation:Humans
    338. Swisher SG, Ajani JA, Komaki R, Nesbitt JC, Correa AM, Cox JD, Lahoti S, Martin F, Putnam JB, Smythe WR, Vaporciyan AA, Walsh GL, Roth JA. Long-term outcome of phase II trial evaluating chemotherapy, chemoradiotherapy, and surgery for locoregionally advanced esophageal cancer. Int J Radiat Oncol Biol Phys. 2003 Sep 01; 57(1):120-7. PMID: 12909224.
      Citations: 21     Fields:    Translation:HumansCTClinical Trials
    339. Ajani JA, Faust J, Yao J, Komaki R, Stevens C, Swisher S, Putnam JB, Vaporciyan A, Smythe R, Walsh G, Rice D, Roth J. Irinotecan/cisplatin followed by 5-FU/paclitaxel/radiotherapy and surgery in esophageal cancer. Oncology (Williston Park). 2003 Sep; 17(9 Suppl 8):20-2. PMID: 14569843.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    340. Virmani A, Rathi A, Sugio K, Sathyanarayana UG, Toyooka S, Kischel FC, Tonk V, Padar A, Takahashi T, Roth JA, Euhus DM, Minna JD, Gazdar AF. Aberrant methylation of TMS1 in small cell, non small cell lung cancer and breast cancer. Int J Cancer. 2003 Aug 20; 106(2):198-204. PMID: 12800194.
      Citations: 28     Fields:    Translation:HumansCells
    341. Mhashilkar AM, Stewart AL, Sieger K, Yang HY, Khimani AH, Ito I, Saito Y, Hunt KK, Grimm EA, Roth JA, Meyn RE, Ramesh R, Chada S. MDA-7 negatively regulates the beta-catenin and PI3K signaling pathways in breast and lung tumor cells. Mol Ther. 2003 Aug; 8(2):207-19. PMID: 12907143.
      Citations: 24     Fields:    Translation:HumansCells
    342. Fang B, Roth JA. Tumor-suppressing gene therapy. Cancer Biol Ther. 2003 Jul-Aug; 2(4 Suppl 1):S115-21. PMID: 14508088.
      Citations: 9     Fields:    Translation:HumansAnimals
    343. Huang X, Lin T, Gu J, Zhang L, Roth JA, Liu J, Fang B. Cell to cell contact required for bystander effect of the TNF-related apoptosis-inducing ligand (TRAIL) gene. Int J Oncol. 2003 Jun; 22(6):1241-5. PMID: 12738989.
      Citations: 12     Fields:    Translation:HumansCells
    344. Pataer A, Chada S, Hunt KK, Roth JA, Swisher SG. Adenoviral melanoma differentiation-associated gene 7 induces apoptosis in lung cancer cells through mitochondrial permeability transition-independent cytochrome c release. J Thorac Cardiovasc Surg. 2003 Jun; 125(6):1328-35. PMID: 12830052.
      Citations: 1     Fields:    Translation:HumansCells
    345. Chada S, Mhashilkar A, Roth JA, Gabrilovich D. Development of vaccines against self-antigens: the p53 paradigm. Curr Opin Drug Discov Devel. 2003 Mar; 6(2):169-73. PMID: 12669451.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    346. Ito I, Began G, Mohiuddin I, Saeki T, Saito Y, Branch CD, Vaporciyan A, Stephens LC, Yen N, Roth JA, Ramesh R. Increased uptake of liposomal-DNA complexes by lung metastases following intravenous administration. Mol Ther. 2003 Mar; 7(3):409-18. PMID: 12668137.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    347. Milas I, Komaki R, Hachiya T, Bubb RS, Ro JY, Langford L, Sawaya R, Putnam JB, Allen P, Cox JD, McDonnell TJ, Brock W, Hong WK, Roth JA, Milas L. Epidermal growth factor receptor, cyclooxygenase-2, and BAX expression in the primary non-small cell lung cancer and brain metastases. Clin Cancer Res. 2003 Mar; 9(3):1070-6. PMID: 12631609.
      Citations: 13     Fields:    Translation:Humans
    348. Kurie JM, Lotan R, Lee JJ, Lee JS, Morice RC, Liu DD, Xu XC, Khuri FR, Ro JY, Hittelman WN, Walsh GL, Roth JA, Minna JD, Hong WK. Treatment of former smokers with 9-cis-retinoic acid reverses loss of retinoic acid receptor-beta expression in the bronchial epithelium: results from a randomized placebo-controlled trial. J Natl Cancer Inst. 2003 Feb 05; 95(3):206-14. PMID: 12569142.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    349. Carboni GL, Gao B, Nishizaki M, Xu K, Minna JD, Roth JA, Ji L. CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity. Oncogene. 2003 Jan 30; 22(4):615-26. PMID: 12555074; PMCID: PMC3484891.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    350. Toyooka S, Maruyama R, Toyooka KO, McLerran D, Feng Z, Fukuyama Y, Virmani AK, Zochbauer-Muller S, Tsukuda K, Sugio K, Shimizu N, Shimizu K, Lee H, Chen CY, Fong KM, Gilcrease M, Roth JA, Minna JD, Gazdar AF. Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer. Int J Cancer. 2003 Jan 10; 103(2):153-60. PMID: 12455028.
      Citations: 80     Fields:    Translation:HumansCells
    351. Swisher SG, Roth JA, Komaki R, Gu J, Lee JJ, Hicks M, Ro JY, Hong WK, Merritt JA, Ahrar K, Atkinson NE, Correa AM, Dolormente M, Dreiling L, El-Naggar AK, Fossella F, Francisco R, Glisson B, Grammer S, Herbst R, Huaringa A, Kemp B, Khuri FR, Kurie JM, Liao Z, McDonnell TJ, Morice R, Morello F, Munden R, Papadimitrakopoulou V, Pisters KM, Putnam JB, Sarabia AJ, Shelton T, Stevens C, Shin DM, Smythe WR, Vaporciyan AA, Walsh GL, Yin M. Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy. Clin Cancer Res. 2003 Jan; 9(1):93-101. PMID: 12538456.
      Citations: 47     Fields:    Translation:HumansCellsCTClinical Trials
    352. Roth JA, Grammer SF. Tumor suppressor gene therapy. Methods Mol Biol. 2003; 223:577-98. PMID: 12777752.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    353. Brose MS, Volpe P, Feldman M, Kumar M, Rishi I, Gerrero R, Einhorn E, Herlyn M, Minna J, Nicholson A, Roth JA, Albelda SM, Davies H, Cox C, Brignell G, Stephens P, Futreal PA, Wooster R, Stratton MR, Weber BL. BRAF and RAS mutations in human lung cancer and melanoma. Cancer Res. 2002 Dec 01; 62(23):6997-7000. PMID: 12460918.
      Citations: 369     Fields:    Translation:HumansCells
    354. Lin T, Huang X, Gu J, Zhang L, Roth JA, Xiong M, Curley SA, Yu Y, Hunt KK, Fang B. Long-term tumor-free survival from treatment with the GFP-TRAIL fusion gene expressed from the hTERT promoter in breast cancer cells. Oncogene. 2002 Nov 14; 21(52):8020-8. PMID: 12439752.
      Citations: 26     Fields:    Translation:HumansCells
    355. Sasaki J, Ramesh R, Chada S, Gomyo Y, Roth JA, Mukhopadhyay T. The anthelmintic drug mebendazole induces mitotic arrest and apoptosis by depolymerizing tubulin in non-small cell lung cancer cells. Mol Cancer Ther. 2002 Nov; 1(13):1201-9. PMID: 12479701.
      Citations: 69     Fields:    Translation:HumansAnimalsCells
    356. Mukhopadhyay T, Sasaki J, Ramesh R, Roth JA. Mebendazole elicits a potent antitumor effect on human cancer cell lines both in vitro and in vivo. Clin Cancer Res. 2002 Sep; 8(9):2963-9. PMID: 12231542.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    357. Hofstetter W, Swisher SG, Correa AM, Hess K, Putnam JB, Ajani JA, Dolormente M, Francisco R, Komaki RR, Lara A, Martin F, Rice DC, Sarabia AJ, Smythe WR, Vaporciyan AA, Walsh GL, Roth JA. Treatment outcomes of resected esophageal cancer. Ann Surg. 2002 Sep; 236(3):376-84; discussion 384-5. PMID: 12192324; PMCID: PMC1422591.
      Citations: 73     Fields:    Translation:Humans
    358. Bubb RS, Komaki R, Hachiya T, Milas I, Ro JY, Langford L, Sawaya R, Putnam JB, Allen P, Cox JD, McDonnell TJ, Brock W, Hong WK, Roth JA, Milas L. Association of Ki-67, p53, and bcl-2 expression of the primary non-small-cell lung cancer lesion with brain metastatic lesion. Int J Radiat Oncol Biol Phys. 2002 Aug 01; 53(5):1216-24. PMID: 12128123.
      Citations: 11     Fields:    Translation:Humans
    359. Tango Y, Fujiwara T, Itoshima T, Takata Y, Katsuda K, Uno F, Ohtani S, Tani T, Roth JA, Tanaka N. Adenovirus-mediated p14ARF gene transfer cooperates with Ad5CMV-p53 to induce apoptosis in human cancer cells. Hum Gene Ther. 2002 Jul 20; 13(11):1373-82. PMID: 12162819.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    360. Gu J, Zhang L, Huang X, Lin T, Yin M, Xu K, Ji L, Roth JA, Fang B. A novel single tetracycline-regulative adenoviral vector for tumor-specific Bax gene expression and cell killing in vitro and in vivo. Oncogene. 2002 Jul 18; 21(31):4757-64. PMID: 12101414.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    361. Saeki T, Mhashilkar A, Swanson X, Zou-Yang XH, Sieger K, Kawabe S, Branch CD, Zumstein L, Meyn RE, Roth JA, Chada S, Ramesh R. Inhibition of human lung cancer growth following adenovirus-mediated mda-7 gene expression in vivo. Oncogene. 2002 Jul 04; 21(29):4558-66. PMID: 12085234.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    362. Vaporciyan AA, Rice D, Correa AM, Walsh G, Putnam JB, Swisher S, Smythe R, Roth J. Resection of advanced thoracic malignancies requiring cardiopulmonary bypass. Eur J Cardiothorac Surg. 2002 Jul; 22(1):47-52. PMID: 12103372.
      Citations: 12     Fields:    Translation:Humans
    363. Swisher SG, Roth JA. Clinical update of Ad-p53 gene therapy for lung cancer. Surg Oncol Clin N Am. 2002 Jul; 11(3):521-35. PMID: 12487055.
      Citations: 10     Fields:    Translation:HumansAnimals
    364. Tanyi JL, Lapushin R, Eder A, Auersperg N, Tabassam FH, Roth JA, Gu J, Fang B, Mills GB, Wolf J. Identification of tissue- and cancer-selective promoters for the introduction of genes into human ovarian cancer cells. Gynecol Oncol. 2002 Jun; 85(3):451-8. PMID: 12051873.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    365. Ji L, Nishizaki M, Gao B, Burbee D, Kondo M, Kamibayashi C, Xu K, Yen N, Atkinson EN, Fang B, Lerman MI, Roth JA, Minna JD. Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo. Cancer Res. 2002 May 01; 62(9):2715-20. PMID: 11980673; PMCID: PMC3478680.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    366. Pataer A, Vorburger SA, Barber GN, Chada S, Mhashilkar AM, Zou-Yang H, Stewart AL, Balachandran S, Roth JA, Hunt KK, Swisher SG. Adenoviral transfer of the melanoma differentiation-associated gene 7 (mda7) induces apoptosis of lung cancer cells via up-regulation of the double-stranded RNA-dependent protein kinase (PKR). Cancer Res. 2002 Apr 15; 62(8):2239-43. PMID: 11956076.
      Citations: 38     Fields:    Translation:HumansCells
    367. Nutt LK, Chandra J, Pataer A, Fang B, Roth JA, Swisher SG, O'Neil RG, McConkey DJ. Bax-mediated Ca2+ mobilization promotes cytochrome c release during apoptosis. J Biol Chem. 2002 Jun 07; 277(23):20301-8. PMID: 11909872.
      Citations: 56     Fields:    Translation:HumansCells
    368. Honda T, Kagawa S, Spurgers KB, Gjertsen BT, Roth JA, Fang B, Lowe SL, Norris JS, Meyn RE, McDonnell TJ. A recombinant adenovirus expressing wild-type Bax induces apoptosis in prostate cancer cells independently of their Bcl-2 status and androgen sensitivity. Cancer Biol Ther. 2002 Mar-Apr; 1(2):163-7. PMID: 12170776.
      Citations: 6     Fields:    Translation:HumansCells
    369. Swisher SG, Roth JA, Carbone DP. Genetic and immunologic therapies for lung cancer. Semin Oncol. 2002 Feb; 29(1 Suppl 4):95-101. PMID: 11894019.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    370. Minna JD, Roth JA, Gazdar AF. Focus on lung cancer. Cancer Cell. 2002 Feb; 1(1):49-52. PMID: 12086887.
      Citations: 189     Fields:    Translation:Humans
    371. Coombes KR, Zhang L, Bueso-Ramos C, Brisbay S, Logothetis C, Roth J, Keating MJ, McDonnell TJ. TAD: a web interface and database for tissue microarrays. Appl Bioinformatics. 2002; 1(3):155-8. PMID: 15130842.
      Citations: 4     Fields:    
    372. Swisher SG, Wynn P, Putnam JB, Mosheim MB, Correa AM, Komaki RR, Ajani JA, Smythe WR, Vaporciyan AA, Roth JA, Walsh GL. Salvage esophagectomy for recurrent tumors after definitive chemotherapy and radiotherapy. J Thorac Cardiovasc Surg. 2002 Jan; 123(1):175-83. PMID: 11782772.
      Citations: 66     Fields:    Translation:Humans
    373. Nutt LK, Pataer A, Pahler J, Fang B, Roth J, McConkey DJ, Swisher SG. Bax and Bak promote apoptosis by modulating endoplasmic reticular and mitochondrial Ca2+ stores. J Biol Chem. 2002 Mar 15; 277(11):9219-25. PMID: 11741880.
      Citations: 80     Fields:    Translation:HumansCells
    374. Grannis FW. Comment on Rosell et al., Roth et al. and Gandara et al., Lung Cancer. Lung Cancer. 2000 Jun; 28(3):247-51. PMID: 10917719.
      Citations:    Fields:    Translation:Humans
    375. Nguyen DM, Chen A, Mixon A, Schrump DS. Sequence-dependent enhancement of paclitaxel toxicity in non-small cell lung cancer by 17-allylamino 17-demethoxygeldanamycin. J Thorac Cardiovasc Surg. 1999 Nov; 118(5):908-15. PMID: 10534697.
      Citations: 5     Fields:    Translation:HumansCells
    376. Estreicher A, Iggo R. Retrovirus-mediated p53 gene therapy. Nat Med. 1996 Nov; 2(11):1163. PMID: 8898732.
      Citations:    Fields:    Translation:AnimalsCells
    377. Krasna MJ, Flowers JL, Attar S, McLaughlin J. Combined thoracoscopic/laparoscopic staging of esophageal cancer. J Thorac Cardiovasc Surg. 1996 Apr; 111(4):800-6; discussion 806-7. PMID: 8614140.
      Citations: 14     Fields:    Translation:Humans
    378. Kandioler D, Dekan G, End A, Pasching E, Buchmayer H, Gnant M, Langmann F, Mannhalter C, Eckersberger F, Wolner E. Molecular genetic differentiation between primary lung cancers and lung metastases of other tumors. J Thorac Cardiovasc Surg. 1996 Apr; 111(4):827-31; discussion 832. PMID: 8614143.
      Citations: 4     Fields:    Translation:Humans
    379. Mathisen DJ, Wain JC, Wright C, Choi N, Carey R, Hilgenberg A, Grossbard M, Lynch T, Grillo H. Assessment of preoperative accelerated radiotherapy and chemotherapy in stage IIIA (N2) non-small-cell lung cancer. J Thorac Cardiovasc Surg. 1996 Jan; 111(1):123-31; discussion 131-3. PMID: 8551756.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    380. Elshami AA, Kucharczuk JC, Sterman DH, Smythe WR, Hwang HC, Amin KM, Litzky LA, Albelda SM, Kaiser LR. The role of immunosuppression in the efficacy of cancer gene therapy using adenovirus transfer of the herpes simplex thymidine kinase gene. Ann Surg. 1995 Sep; 222(3):298-307; 307-10. PMID: 7677460; PMCID: PMC1234809.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    381. Green MR, Cox JD, Ardizzoni A, Arriagada R, Bureau G, Darwish S, Deneffe G, Fukuoka M, Joseph D, Komaki R, et al. Endpoints for multimodal clinical trials in stage III non-small cell lung cancer (NSCLC): a consensus report. Lung Cancer. 1994 Nov; 11 Suppl 3:S11-3. PMID: 7704502.
      Citations: 2     Fields:    Translation:Humans
    382. Green MR, Ginsberg R, Ardizzoni A, Choi N, Darwish S, Fukuoka M, Giner V, Grunenwald D, Harper P, Kho S, et al. Induction therapy for stage III NSCLC: a consensus report. Lung Cancer. 1994 Nov; 11 Suppl 3:S9-10. PMID: 7704518.
      Citations:    Fields:    Translation:Humans
    383. Browne MJ, Potter D, Gress J, Cotton D, Hiemenz J, Thaler M, Hathorn J, Brower S, Gill V, Glatstein E, et al. A randomized trial of open lung biopsy versus empiric antimicrobial therapy in cancer patients with diffuse pulmonary infiltrates. J Clin Oncol. 1990 Feb; 8(2):222-9. PMID: 2299367.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    384. Ognibene FP, Pass HI, Roth JA, Shelhamer JH, Milne EN. Role of imaging and interventional techniques in the diagnosis of respiratory disease in the immunocompromised host. J Thorac Imaging. 1988 Apr; 3(2):1-20. PMID: 3283372.
      Citations:    Fields:    Translation:Humans
    385. Ramming KP, Roth JA, Mulder DG. Surgical management of extensive tracheal lesions. Am J Surg. 1979 Jul; 138(1):80-8. PMID: 464213.
      Citations: 1     Fields:    Translation:Humans
    386. Roth JA, Zuckerbraun L, Cohn D. Lymphosarcoma presenting as a parotid mass. Ear Nose Throat J. 1978 Oct; 57(10):434-8. PMID: 581752.
      Citations:    Fields:    Translation:Humans
    387. McAvoy JM, Roth J, Rees WV, Orr F, Dainko EA. Role of ultrasonography in the primary diagnosis of cholelithiasis: an analysis of fifty cases. Am J Surg. 1978 Sep; 136(3):309-12. PMID: 707695.
      Citations: 4     Fields:    Translation:Humans
    388. Williams M, Harr A, Parks L, Roth J. Proceedings; Rejection and repair of endothelium in major vessel transplants. J Cardiovasc Surg (Torino). 1976 Jan-Feb; 17(1):94-5. PMID: 1245531.
      Citations:    Fields:    Translation:HumansAnimals
    389. Williams GM, ter Haar A, Krajewski C, Parks LC, Roth J. Rejection and repair of endothelium in major vessel transplants. Surgery. 1975 Dec; 78(6):694-706. PMID: 1188613.
      Citations: 8     Fields:    Translation:Animals
    390. Golub SH, Roth JA, Forsythe A, Morton DL. In vitro monitoring of cellular function during BCG immunotherapy. Bibl Haematol. 1975 Oct; (43):270-3. PMID: 786261.
      Citations:    Fields:    Translation:HumansCells
    391. Roth JA, Eilber FR, Nizze JA, Morton DL. Lack of correlation between skin reactivity to dinitrochlorobenzene and croton oil in patients with cancer. N Engl J Med. 1975 Aug 21; 293(8):388-9. PMID: 1152937.
      Citations: 2     Fields:    Translation:Humans
    392. Roth JA, ter Haar AM, Krajewski CA, Williams GM. Nucleic acid synthesis in allograft endothelium. Surg Forum. 1971; 22:264-6. PMID: 5121370.
      Citations:    Fields:    Translation:Animals
    393. Inhibition of RNA-dependent protein kinase (PKR) leads to cancer cell death and increases chemosensitivity. Cancer Biology and Therapy. 8:241-248.
    394. Gene replacement strategies for lung cancer. Seminars in Radiation Oncology. 6:105-109.
    395. Enhancement of lymphokine-activated killer cell cytotoxicity with interleukin-2, tumor necrosis factor-alpha, and OKT3 against primary lung cancer targets. Surgical Forum. 39:454-456.
    396. Gene therapy for cancer. Archive of Oncology. 5:32.
    397. Lung Cancer Surgical Practice Guidelines. Oncology. 11:889-895.
    398. Tp53 gene therapy for cancer treatment and prevention. 189-208.
    399. Human tumor antigen expression is induced on murine 3T3 cells following transformation by human oncogenes. Federation Proceedings. 44.
    400. Exogenous restoration of TUSC2 expression induces responsiveness to erlotinib in wildtype epidermal growth factor receptor (EGFR) lung cancer cells through context specific pathways resulting in enhanced therapeutic efficacy. PLoS One. 10.
    401. Gene therapy for lung cancer. 431-438.
    402. Human tumor cell growth inhibition by a human tumor-derived glycoprotein. Surgical Forum. VOL. 35:394-396.
    403. A Rapid Assay for Stimulation of Human Lymphocytes by Tumor-associated Antigens. Cancer Research. 36:3001-3010.
    404. Gene therapy for lung cancer. Critical Reviews in Oncogenesis. 21:115-124.
    405. A novel alteration in the epidermal growth factor receptor gene is frequently detected in human non-small cell lung cancer. Lung Cancer. 6:65-72.
    406. Scientific Reports. 6.
    407. Erratum. Cancer Gene Therapy. 12:340.
    408. Biologic therapy for lung cancer. Cancer Bulletin. 43:100-108.
    409. MiRNA-related genetic variations associated with radiotherapy-induced toxicities in patients with locally advanced non-small cell lung cancer. PLoS One. 11.
    410. Glycemic index, glycemic load, and lung cancer risk in non-hispanic whites. Cancer Epidemiology Biomarkers and Prevention. 25:532-539.
    411. Studies of lymphocyte stimulation to tumor-associated antigen - II. Comparison of extracts from fresh human tumors with tissue culture cell lines. Cancer Immunology Immunotherapy. 7:25-29.
    412. Novel and Emerging Agents in NSCLC. 464-478.
    413. Malignant degeneration of Barrett's esophagsu. Diseases of the Esophagus. 8:99-103.
    414. Diagnosis and management of benign esophageal tumors. Cancer Bulletin. 47:396-401.
    415. Expression of sulfotransferase SULT1A1 in cancer cells predicts susceptibility to the novel anticancer agent NSC-743380. Oncotarget. 6:345-354.
    416. Detection of siRNA-mediated target mRNA cleavage activities in human cells by a novel stem-loop array RT-PCR analysis. Biochemistry and Biophysics Reports. 6:16-23.
    417. Retrovirus-mediated wild-type p53 gene transfer to tumors of patients with lung cancer. Pneumologie. 51:686.
    418. Journal of Thoracic Oncology. Journal of Thoracic Oncology. 2.
    419. Studies of lymphocyte stimulation to tumor-associated antigen - I. Uptake of lymphocyte protein and nucleic acid precursors in response to autologous and allogeneic tumor-associated antigen solubilized from human tumors. Cancer Immunology Immunotherapy. 7:19-23.
    420. Immunotoxin to the GP74 c-Ha-ras-linked tumor antigen. 413-415.
    421. Regression of radiation- and chemotherapy-resistant non-small cell lung cancer treated with combination immunotherapy. Cancer Bulletin. 43:181-184.
    422. Pseudosarcomatous tumors of the lower urinary tract [3]. American Journal of Clinical Pathology. 98:271.
    423. Multifunctional tumor-targeted nanoparticles for lung cancer. 15-44.
    424. TUSC2(FUS1)-erlotinib Induced Vulnerabilities in Epidermal Growth Factor Receptor(EGFR) Wildtype Non-small Cell Lung Cancer(NSCLC) Targeted by the Repurposed Drug Auranofin. Scientific Reports. 6.
    425. Omental reinforcement of the thoracic esophagogastric anastomosis. Journal of Thoracic and Cardiovascular Surgery.
    426. Lung Cancer, Third Edition.
    427. Impact of a fast-track esophagectomy protocol on esophageal cancer patient outcomes and hospital charges. Annals of Surgery. 261:1114-1123.
    428. A large scale method of separating multiple lymphokines secreted by the murine el-4 thymoma. Immunopharmacology and Immunotoxicology. 7:17-31.
    429. Auranofin-mediated inhibition of PI3K/AKT/mTOR axis and anticancer activity in non-small cell lung cancer cells. Oncotarget. 7:3548-3558.
    430. Antisense technology. Cancer Bulletin. 47:420-422.
    431. Thoracic metastases from sarcoma. Oncology. 25.
    432. Effects of low dose OKT3 induction on the antitumor immune response in cancer patients receiving interleukin-2 (IL-2) and tumor necrosis factor-alpha (TNF). Surgical Forum. 41:434-436.
    433. Quality of life after video-assisted surgery for lung cancer. The Lancet Oncology. 17:e315-e316.
    434. Drug resistance in lung cancer. Lung Cancer: Targets and Therapy. 1:23-36.
    435. Cells transformed by a human oncogene (c-Ha-ras) and human tumors express a common cell surface antigen.
    436. Redefining the lowest exercise peak oxygen consumption acceptable for lung resection of high risk patients. Chest. 110.
    437. Targeted Genetic Therapy for Lung Cancer. 411-420.
    438. Automated detection of genetic abnormalities combined with cytology in sputum is a sensitive predictor of lung cancer (Modern Pathology (2008) 21, (950-960) DOI. Modern Pathology. 21:1065.
    439. Reduction of pulmonary metastases following in vivo administration of anti-CD3, interleukin-2, and tumor necrosis factor-α in mice. Surgical Forum. 40:423-425.
    440. Targeting cancer genes. Cancer Bulletin. 45:171-177.
    441. Erratum. Modern Pathology. 22:734-736.
    442. Preface. Unknown Journal. xiii.
    443. Preface. Unknown Journal.
    444. Different dietary patterns and reduction of lung cancer risk. Scientific Reports. 6.
    445. Results of Postdischarge Nursing Telephone Assessments. Annals of Thoracic Surgery.
    446. Biomarkers predict p53 gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck. Clinical Cancer Research. 15:7719-7725.
    447. Lung Cancer.
    448. Resection of Recurrent Pulmonary Metastases in Patients With Soft-Tissue Sarcomas. Archives of Surgery. 121:1248-1252.
    449. 3p21.3 tumor suppressor cluster. Future Oncology. 1:79-92.
    450. Reply. Annals of Thoracic Surgery. 91:1653.
    451. The Influence of Reconstructive Technique on Perioperative Pulmonary and Infectious Outcomes Following Chest Wall Resection. Annals of Thoracic Surgery. 102:1653-1659.
    452. Establishing a GMP manufacturing site for nanoparticles. 413-416.
    453. Therapy for metastasis. Cancer Bulletin. 39.
    454. Molecular pathogenesis of adenocarcinomas in Barrett's esophagus. Onkologie. 20:36-40.
    455. RNA-dependent protein kinase (PKR) depletes nutrients, inducing phosphorylation of AMP-activated kinase in lung cancer. Oncotarget. 6:11114-11124.
    456. Local and systemic strategies for gene replacement for cancer. British Journal of Cancer. 78:142.
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