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RAGHU KALLURI

TitleProfessor
InstitutionMD Anderson
DepartmentCancer Biology
Address1881 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. LeBleu VS, Kanasaki K, Lovisa S, Alge JL, Kim J, Chen Y, Teng Y, Gerami-Naini B, Sugimoto H, Kato N, Revuelta I, Grau N, Sleeman JP, Taduri G, Kizu A, Rafii S, Hochedlinger K, Quaggin SE, Kalluri R. Genetic reprogramming with stem cells regenerates glomerular epithelial podocytes in Alport syndrome. Life Sci Alliance. 2024 Jun; 7(6). PMID: 38561223; PMCID: PMC10985218.
      Citations:    Fields:    Translation:AnimalsCells
    2. Li B, Kugeratski FG, Kalluri R. A novel machine learning algorithm selects proteome signature to specifically identify cancer exosomes. Elife. 2024 Mar 26; 12. PMID: 38529947; PMCID: PMC10965221.
      Citations:    Fields:    Translation:HumansCells
    3. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Author Correction: Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2024 Mar; 30(3):908. PMID: 38017076.
      Citations:    Fields:    
    4. McAndrews KM, Mahadevan KK, Kalluri R. Mouse Models to Evaluate the Functional Role of the Tumor Microenvironment in Cancer Progression and Therapy Responses. Cold Spring Harb Perspect Med. 2024 Jan 08. PMID: 38191175.
      Citations:    Fields:    
    5. Kapoor KS, Kong S, Sugimoto H, Guo W, Boominathan V, Chen YL, Biswal SL, Terlier T, McAndrews KM, Kalluri R. Single extracellular vesicle imaging and computational analysis identifies inherent architectural heterogeneity. bioRxiv. 2023 Dec 12. PMID: 38168235; PMCID: PMC10760062.
      Citations:    
    6. Kugeratski FG, LeBleu VS, Dowlatshahi DP, Sugimoto H, Arian KA, Fan Y, Huang L, Wells D, Lilla S, Hodge K, Zanivan S, McAndrews KM, Kalluri R. Engineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity. bioRxiv. 2023 Nov 04. PMID: 37961535; PMCID: PMC10635085.
      Citations:    
    7. Ferreira D, Santos-Pereira C, Costa M, Afonso J, Yang S, Hensel J, McAndrews KM, Longatto-Filho A, Fernandes R, Melo JB, Baltazar F, Moreira JN, Kalluri R, Rodrigues LR. Exosomes modified with anti-MEK1 siRNA lead to an effective silencing of triple negative breast cancer cells. Biomater Adv. 2023 Nov; 154:213643. PMID: 37778291.
      Citations:    Fields:    Translation:HumansCells
    8. Thorlacius-Ussing J, Jensen C, Nissen NI, Cox TR, Kalluri R, Karsdal M, Willumsen N. The collagen landscape in cancer: profiling collagens in tumors and in circulation reveals novel markers of cancer-associated fibroblast subtypes. J Pathol. 2024 01; 262(1):22-36. PMID: 37728068.
      Citations: 3     Fields:    Translation:HumansCells
    9. Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Paradiso F, Sugimoto H, Arian KA, Ying H, Barekatain Y, Sthanam LK, Kelly PJ, Maitra A, Heffernan TP, Kalluri R. KRASG12D inhibition reprograms the microenvironment of early and advanced pancreatic cancer to promote FAS-mediated killing by CD8+ T?cells. Cancer Cell. 2023 09 11; 41(9):1606-1620.e8. PMID: 37625401; PMCID: PMC10785700.
      Citations: 6     Fields:    Translation:HumansCells
    10. Mahadevan KK, LeBleu VS, Ramirez EV, Chen Y, Li B, Sockwell AM, Gagea M, Sugimoto H, Sthanam LK, Tampe D, Zeisberg M, Ying H, Jain AK, DePinho RA, Maitra A, McAndrews KM, Kalluri R. Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T?cells. Dev Cell. 2023 09 11; 58(17):1562-1577.e8. PMID: 37625403; PMCID: PMC10810082.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    11. LeBleu VS, Dai J, Tsutakawa S, MacDonald BA, Alge JL, Sund M, Xie L, Sugimoto H, Tainer J, Zon LI, Kalluri R. Identification of unique a4 chain structure and conserved antiangiogenic activity of a3NC1 type IV collagen in zebrafish. Dev Dyn. 2023 07; 252(7):1046-1060. PMID: 37002899; PMCID: PMC10524752.
      Citations:    Fields:    Translation:HumansAnimalsCells
    12. Kalluri R, McAndrews KM. The role of extracellular vesicles in cancer. Cell. 2023 04 13; 186(8):1610-1626. PMID: 37059067; PMCID: PMC10484374.
      Citations: 10     Fields:    Translation:HumansCells
    13. Mahadevan KK, Dyevoich AM, Chen Y, Li B, Sugimoto H, Sockwell AM, McAndrews KM, Wang H, Shalapour S, Watowich SS, Kalluri R. Antigen-presenting type-I conventional dendritic cells facilitate curative checkpoint blockade immunotherapy in pancreatic cancer. bioRxiv. 2023 Mar 06. PMID: 36945457; PMCID: PMC10028824.
      Citations:    
    14. Mahadevan KK, McAndrews KM, LeBleu VS, Yang S, Lyu H, Li B, Sockwell AM, Kirtley ML, Morse SJ, Moreno Diaz BA, Kim MP, Feng N, Lopez AM, Guerrero PA, Sugimoto H, Arian KA, Ying H, Barekatain Y, Kelly PJ, Maitra A, Heffernan TP, Kalluri R. Oncogenic Kras G12D specific non-covalent inhibitor reprograms tumor microenvironment to prevent and reverse early pre-neoplastic pancreatic lesions and in combination with immunotherapy regresses advanced PDAC in a CD8 + T cells dependent manner. bioRxiv. 2023 Feb 18. PMID: 36824971; PMCID: PMC9948969.
      Citations:    
    15. Haltom AR, Hassen WE, Hensel J, Kim J, Sugimoto H, Li B, McAndrews KM, Conner MR, Kirtley ML, Luo X, Xie B, Volpert OV, Olalekan S, Maltsev N, Basu A, LeBleu VS, Kalluri R. Engineered exosomes targeting MYC reverse the proneural-mesenchymal transition and extend survival of glioblastoma. Extracell Vesicle. 2022 Dec; 1. PMID: 37503329; PMCID: PMC10373511.
      Citations: 3     
    16. Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Weitz J, Rahbari N, Reissfelder C, Pilarsky C, Fraga MF, Piwnica-Worms D, Kalluri R. Author Correction: Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2022 Oct; 610(7932):E15-E17. PMID: 36198804.
      Citations:    Fields:    
    17. Chen Y, Yang S, Tavormina J, Wang H, Mahadevan KK, Wu CJ, Sugimoto H, Chang CC, Jenq RR, McAndrews KM, Kalluri R, Tampe D, Zeisberg M. Oncogenic collagen I homotrimers from cancer cells bind to a3?1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer. Cancer Cell. 2022 08 08; 40(8):818-834.e9. PMID: 35868307; PMCID: PMC9831277.
      Citations:    Fields:    
    18. Barekatain Y, Khadka S, Harris K, Delacerda J, Yan VC, Chen KC, Pham CD, Uddin MN, Avritcher R, Eisenberg EJ, Kalluri R, Millward SW, Muller FL. Quantification of Phosphonate Drugs by 1H-31P HSQC Shows That Rats Are Better Models of Primate Drug Exposure than Mice. Anal Chem. 2022 07 19; 94(28):10045-10053. PMID: 35792073.
      Citations:    Fields:    Translation:Animals
    19. McAndrews KM, Chen Y, Darpolor JK, Zheng X, Yang S, Carstens JL, Li B, Wang H, Miyake T, Correa de Sampaio P, Kirtley ML, Natale M, Wu CC, Sugimoto H, LeBleu VS, Kalluri R. Identification of Functional Heterogeneity of Carcinoma-Associated Fibroblasts with Distinct IL6-Mediated Therapy Resistance in Pancreatic Cancer. Cancer Discov. 2022 06 02; 12(6):1580-1597. PMID: 35348629; PMCID: PMC9399904.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    20. McAndrews KM, Miyake T, Ehsanipour EA, Kelly PJ, Becker LM, McGrail DJ, Sugimoto H, LeBleu VS, Ge Y, Kalluri R. Dermal aSMA+ myofibroblasts orchestrate skin wound repair via ?1 integrin and independent of type I collagen production. EMBO J. 2022 04 04; 41(7):e109470. PMID: 35212000; PMCID: PMC8982612.
      Citations: 3     Fields:    Translation:AnimalsCells
    21. El-Shennawy L, Hoffmann AD, Dashzeveg NK, McAndrews KM, Mehl PJ, Cornish D, Yu Z, Tokars VL, Nicolaescu V, Tomatsidou A, Mao C, Felicelli CJ, Tsai CF, Ostiguin C, Jia Y, Li L, Furlong K, Wysocki J, Luo X, Ruivo CF, Batlle D, Hope TJ, Shen Y, Chae YK, Zhang H, LeBleu VS, Shi T, Swaminathan S, Luo Y, Missiakas D, Randall GC, Demonbreun AR, Ison MG, Kalluri R, Fang D, Liu H. Circulating ACE2-expressing extracellular vesicles block broad strains of SARS-CoV-2. Nat Commun. 2022 01 20; 13(1):405. PMID: 35058437; PMCID: PMC8776790.
      Citations: 5     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    22. Melo CA, Campos-Laborie F, Moutinho-Ribeiro P, Ciordia S, Goodrich D, Kouzarides T, Macedo G, Kalluri R, Ruivo CF, Bastos N, Adem B, Batista I, Duraes C, Castaldo SA, Mor?o B, Costa-Pinto A, Silva S, Osorio H, Costa JL, Cavadas B, Pereira L, Maio R, Carneiro F, Cravo M, Machado JC, Melo SA. Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression. Gut. 2022 01 10. PMID: 35012996; PMCID: PMC9271144.
      Citations: 2     Fields:    
    23. Chen Y, Yang S, Lovisa S, Ambrose CG, McAndrews KM, Sugimoto H, Kalluri R. Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta. Nat Commun. 2021 12 10; 12(1):7199. PMID: 34893625; PMCID: PMC8664945.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    24. Yang J, Antin P, Berx G, Bronner M, Campbell K, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, Goodall GJ, Hadjantonakis AK, Huang RYJ, Kalcheim C, Kalluri R, Kang Y, Khew-Goodall Y, Levine H, Liu J, Longmore GD, Mani SA, Mayor R, McClay D, Mostov KE, Newgreen DF, Runyan R, Savagner P, Stanger B, Takahashi Y, Takeichi M, Thiery JP, Thompson EW, Weinberg RA, Williams ED, Xing J, Zhou BP, Sheng G, EMT International Association (TEMTIA), Blanpain C, Brabletz T, Cano A, Garc?a de Herreros A, Massagu? J, Nieto MA, Puisieux A, Stemmler MP, Theveneau E. Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2021 Dec; 22(12):834. PMID: 34654908; PMCID: PMC8604719.
      Citations: 2     Fields:    
    25. Chen Y, McAndrews KM, Kalluri R. Clinical and therapeutic relevance of cancer-associated fibroblasts. Nat Rev Clin Oncol. 2021 12; 18(12):792-804. PMID: 34489603; PMCID: PMC8791784.
      Citations: 27     Fields:    Translation:HumansCells
    26. McAndrews KM, Xiao F, Chronopoulos A, LeBleu VS, Kugeratski FG, Kalluri R. Exosome-mediated delivery of CRISPR/Cas9 for targeting of oncogenic KrasG12D in pancreatic cancer. Life Sci Alliance. 2021 09; 4(9). PMID: 34282051; PMCID: PMC8321670.
      Citations: 8     Fields:    Translation:AnimalsCells
    27. Barekatain Y, Ackroyd JJ, Yan VC, Khadka S, Wang L, Chen KC, Poral AH, Tran T, Georgiou DK, Arthur K, Lin YH, Satani N, Ballato ES, Behr EI, deCarvalho AC, Verhaak RGW, de Groot J, Huse JT, Asara JM, Kalluri R, Muller FL. Homozygous MTAP deletion in primary human glioblastoma is not associated with elevation of methylthioadenosine. Nat Commun. 2021 07 09; 12(1):4228. PMID: 34244484; PMCID: PMC8270912.
      Citations: 2     Fields:    Translation:HumansCells
    28. Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, Saito Y, Savage T, Wells RG, Mack M, Zender L, Arpaia N, Remotti HE, Rabadan R, Sims P, Leblond AL, Weber A, Riener MO, Stockwell BR, Gaublomme J, Llovet JM, Kalluri R, Michalopoulos GK, Seki E, Sia D, Chen X, Califano A, Schwabe RF. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. 2021 Jun 14; 39(6):883. PMID: 34129825; PMCID: PMC8532387.
      Citations: 6     Fields:    
    29. McAndrews KM, Kwak C, Sugimoto H, Zheng X, Li B, Kirtley ML, LeBleu VS, Kalluri R, V?zquez-Arregu?n K. aSMA+ fibroblasts suppress Lgr5+ cancer stem cells and restrain colorectal cancer progression. Oncogene. 2021 07; 40(26):4440-4452. PMID: 34108617; PMCID: PMC9150816.
      Citations: 6     Fields:    Translation:AnimalsCells
    30. Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R. Quantitative proteomics identifies the core proteome of exosomes with syntenin-1 as the highest abundant protein and a putative universal biomarker. Nat Cell Biol. 2021 06; 23(6):631-641. PMID: 34108659; PMCID: PMC9290189.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    31. Bhattacharjee S, Hamberger F, Ravichandra A, Miller M, Nair A, Affo S, Filliol A, Chin L, Savage TM, Yin D, Wirsik NM, Mehal A, Arpaia N, Seki E, Mack M, Zhu D, Sims PA, Kalluri R, Stanger BZ, Olive KP, Schmidt T, Wells RG, Mederacke I, Schwabe RF. Tumor restriction by type I collagen opposes tumor-promoting effects of cancer-associated fibroblasts. J Clin Invest. 2021 06 01; 131(11). PMID: 33905375; PMCID: PMC8159701.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    32. Zhou X, Kurywchak P, Wolf-Dennen K, Che SPY, Sulakhe D, D'Souza M, Xie B, Maltsev N, Gilliam TC, Wu CC, McAndrews KM, LeBleu VS, McConkey DJ, Volpert OV, Pretzsch SM, Czerniak BA, Dinney CP, Kalluri R. Unique somatic variants in DNA from urine exosomes of individuals with bladder cancer. Mol Ther Methods Clin Dev. 2021 Sep 10; 22:360-376. PMID: 34514028; PMCID: PMC8408559.
      Citations: 2     
    33. Tang M, Chen Y, Li B, Sugimoto H, Yang S, Yang C, LeBleu VS, McAndrews KM, Kalluri R. Therapeutic targeting of STAT3 with small interference RNAs and antisense oligonucleotides embedded exosomes in liver fibrosis. FASEB J. 2021 05; 35(5):e21557. PMID: 33855751; PMCID: PMC10851328.
      Citations: 5     Fields:    Translation:AnimalsCells
    34. Affo S, Nair A, Brundu F, Ravichandra A, Bhattacharjee S, Matsuda M, Chin L, Filliol A, Wen W, Song X, Decker A, Worley J, Caviglia JM, Yu L, Yin D, Saito Y, Savage T, Wells RG, Mack M, Zender L, Arpaia N, Remotti HE, Rabadan R, Sims P, Stockwell BR, Gaublomme J, Kalluri R, Michalopoulos GK, Seki E, Sia D, Chen X, Califano A, Schwabe RF, Leblond AL, Weber A, Riener MO, Llovet JM. Promotion of cholangiocarcinoma growth by diverse cancer-associated fibroblast subpopulations. Cancer Cell. 2021 06 14; 39(6):866-882.e11. PMID: 33930309; PMCID: PMC8241235.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    35. Carstens JL, Yang S, Correa de Sampaio P, Zheng X, Barua S, McAndrews KM, Rao A, Burks JK, Rhim AD, Kalluri R. Stabilized epithelial phenotype of cancer cells in primary tumors leads to increased colonization of liver metastasis in pancreatic cancer. Cell Rep. 2021 04 13; 35(2):108990. PMID: 33852841; PMCID: PMC8078733.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    36. McAndrews KM, Che SPY, LeBleu VS, Kalluri R. Effective delivery of STING agonist using exosomes suppresses tumor growth and enhances antitumor immunity. J Biol Chem. 2021 Jan-Jun; 296:100523. PMID: 33711340; PMCID: PMC8042450.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    37. Chen Y, Kim J, Yang S, Wang H, Wu CJ, Sugimoto H, LeBleu VS, Kalluri R. Type I collagen deletion in aSMA+ myofibroblasts augments immune suppression and accelerates progression of pancreatic cancer. Cancer Cell. 2021 04 12; 39(4):548-565.e6. PMID: 33667385; PMCID: PMC8423173.
      Citations: 61     Fields:    Translation:AnimalsCells
    38. Kugeratski FG, McAndrews KM, Kalluri R. Multifunctional Applications of Engineered Extracellular Vesicles in the Treatment of Cancer. Endocrinology. 2021 03 01; 162(3). PMID: 33411885; PMCID: PMC8502448.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    39. Zhou X, Xiao F, Sugimoto H, Li B, McAndrews KM, Kalluri R. Acute Kidney Injury Instigates Malignant Renal Cell Carcinoma via CXCR2 in Mice with Inactivated Trp53 and Pten in Proximal Tubular Kidney Epithelial Cells. Cancer Res. 2021 05 15; 81(10):2690-2702. PMID: 33558337.
      Citations: 2     Fields:    Translation:AnimalsCells
    40. Parchem JG, Kanasaki K, Lee SB, Kanasaki M, Yang JL, Xu Y, Earl KM, Keuls RA, Gattone VH, Kalluri R. STOX1 deficiency is associated with renin-mediated gestational hypertension and placental defects. JCI Insight. 2021 01 25; 6(2). PMID: 33301424; PMCID: PMC7934881.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    41. McAndrews KM, Chen Y, Kalluri R. Stromal Cells Exhibit Prevalent Genetic Aberrations in Colorectal Cancer. Cancer Cell. 2020 12 14; 38(6):774-775. PMID: 33321084.
      Citations: 3     Fields:    Translation:HumansCells
    42. Hensel J, McAndrews KM, McGrail DJ, Dowlatshahi DP, LeBleu VS, Kalluri R. Protection against SARS-CoV-2 by BCG vaccination is not supported by epidemiological analyses. Sci Rep. 2020 10 27; 10(1):18377. PMID: 33110184; PMCID: PMC7591473.
      Citations: 32     Fields:    Translation:HumansPHPublic Health
    43. Chronopoulos A, Kalluri R. Emerging role of bacterial extracellular vesicles in cancer. Oncogene. 2020 11; 39(46):6951-6960. PMID: 33060855; PMCID: PMC7557313.
      Citations: 25     Fields:    Translation:HumansCells
    44. Kugeratski FG, Kalluri R. Exosomes as mediators of immune regulation and immunotherapy in cancer. FEBS J. 2021 01; 288(1):10-35. PMID: 32910536; PMCID: PMC9116040.
      Citations: 38     Fields:    Translation:HumansCells
    45. McAndrews KM, Dowlatshahi DP, Dai J, Becker LM, Hensel J, Snowden LM, Leveille JM, Brunner MR, Holden KW, Hopkins NS, Harris AM, Kumpati J, Whitt MA, Lee JJ, Ostrosky-Zeichner LL, Papanna R, LeBleu VS, Allison JP, Kalluri R. Heterogeneous antibodies against SARS-CoV-2 spike receptor binding domain and nucleocapsid with implications for COVID-19 immunity. JCI Insight. 2020 09 17; 5(18). PMID: 32796155; PMCID: PMC7526535.
      Citations: 64     Fields:    Translation:HumansCellsPHPublic Health
    46. McAndrews KM, Kalluri R. A map of human breast cancer: new players in stromal-immune crosstalk. EMBO J. 2020 10 01; 39(19):e106368. PMID: 32909627; PMCID: PMC7527925.
      Citations: 2     Fields:    Translation:HumansCells
    47. McGrail DJ, Dai J, McAndrews KM, Kalluri R. Enacting national social distancing policies corresponds with dramatic reduction in COVID19 infection rates. PLoS One. 2020; 15(7):e0236619. PMID: 32730356; PMCID: PMC7392246.
      Citations: 36     Fields:    Translation:HumansCellsPHPublic Health
    48. Xunian Z, Kalluri R. Biology and therapeutic potential of mesenchymal stem cell-derived exosomes. Cancer Sci. 2020 Sep; 111(9):3100-3110. PMID: 32639675; PMCID: PMC7469857.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    49. Lovisa S, Fletcher-Sananikone E, Sugimoto H, Hensel J, Lahiri S, Hertig A, Taduri G, Lawson E, Dewar R, Revuelta I, Kato N, Wu CJ, Bassett RL, Putluri N, LeBleu VS, Kalluri R, Zeisberg M, Zeisberg EM. Endothelial-to-mesenchymal transition compromises vascular integrity to induce Myc-mediated metabolic reprogramming in kidney fibrosis. Sci Signal. 2020 06 09; 13(635). PMID: 32518142; PMCID: PMC7790440.
      Citations: 17     Fields:    Translation:Animals
    50. Becker LM, O'Connell JT, Vo AP, Cain MP, Bizarro L, Sugimoto H, McGow AK, Asara JM, Lovisa S, McAndrews KM, Zielinski R, Lorenzi PL, Raza S, LeBleu VS, Kalluri R, Tampe D, Zeisberg M. Epigenetic Reprogramming of Cancer-Associated Fibroblasts Deregulates Glucose Metabolism and Facilitates Progression of Breast Cancer. Cell Rep. 2020 06 02; 31(9):107701. PMID: 32492417; PMCID: PMC7339325.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    51. Kalluri R. Isaiah Joshua ('Josh') Fidler 1936-2020. Nat Cancer. 2020 06; 1(6):573-574. PMID: 35121977.
      Citations:    
    52. Hou P, Kapoor A, Zhang Q, Li J, Wu CJ, Li J, Lan Z, Tang M, Ma X, Ackroyd JJ, Kalluri R, Zhang J, Jiang S, Spring DJ, Wang YA, DePinho RA. Tumor Microenvironment Remodeling Enables Bypass of Oncogenic KRAS Dependency in Pancreatic Cancer. Cancer Discov. 2020 07; 10(7):1058-1077. PMID: 32341020; PMCID: PMC7334087.
      Citations: 33     Fields:    Translation:Humans
    53. Yang J, Antin P, Berx G, Bronner M, Campbell K, Casanova J, Christofori G, Dedhar S, Derynck R, Ford HL, Fuxe J, Goodall GJ, Hadjantonakis AK, Huang RYJ, Kalcheim C, Kalluri R, Kang Y, Khew-Goodall Y, Levine H, Liu J, Longmore GD, Mani SA, Mayor R, McClay D, Mostov KE, Newgreen DF, Runyan R, Savagner P, Stanger B, Takahashi Y, Takeichi M, Thiery JP, Thompson EW, Weinberg RA, Williams ED, Xing J, Zhou BP, Sheng G, EMT International Association (TEMTIA), Blanpain C, Brabletz T, Cano A, Garc?a de Herreros A, Massagu? J, Nieto MA, Puisieux A, Stemmler MP, Theveneau E. Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2020 06; 21(6):341-352. PMID: 32300252; PMCID: PMC7250738.
      Citations: 368     Fields:    Translation:HumansAnimals
    54. LeBleu VS, Kalluri R. Exosomes as a Multicomponent Biomarker Platform in Cancer. Trends Cancer. 2020 09; 6(9):767-774. PMID: 32307267.
      Citations: 68     Fields:    Translation:HumansCells
    55. Parchem JG, Brock CO, Chen HY, Kalluri R, Barton JR, Sibai BM, Preeclampsia Triage by Rapid Assay Trial (PETRA) Investigators. Placental Growth Factor and the Risk of Adverse Neonatal and Maternal Outcomes. Obstet Gynecol. 2020 03; 135(3):665-673. PMID: 32028495.
      Citations: 3     Fields:    Translation:Humans
    56. Kalluri R, LeBleu VS. The biology, function, and biomedical applications of exosomes. Science. 2020 02 07; 367(6478). PMID: 32029601; PMCID: PMC7717626.
      Citations: 1149     Fields:    Translation:HumansAnimalsCells
    57. Helmink BA, Reddy SM, Gao J, Zhang S, Basar R, Thakur R, Yizhak K, Sade-Feldman M, Blando J, Han G, Gopalakrishnan V, Xi Y, Zhao H, Amaria RN, Tawbi HA, Cogdill AP, Liu W, LeBleu VS, Kugeratski FG, Patel S, Davies MA, Hwu P, Lee JE, Gershenwald JE, Lucci A, Arora R, Woodman S, Keung EZ, Gaudreau PO, Reuben A, Spencer CN, Burton EM, Haydu LE, Lazar AJ, Zapassodi R, Hudgens CW, Ledesma DA, Ong S, Bailey M, Warren S, Rao D, Krijgsman O, Rozeman EA, Peeper D, Blank CU, Schumacher TN, Butterfield LH, Zelazowska MA, McBride KM, Kalluri R, Allison J, Petitprez F, Fridman WH, Hacohen N, Rezvani K, Sharma P, Tetzlaff MT, Wang L, Wargo JA, Saut?s-Fridman C. B cells and tertiary lymphoid structures promote immunotherapy response. Nature. 2020 01; 577(7791):549-555. PMID: 31942075; PMCID: PMC8762581.
      Citations: 512     Fields:    Translation:HumansCells
    58. Sudhakar A, Nyberg P, Keshamouni VG, Mannam AP, Li J, Sugimoto H, Cosgrove D, Kalluri R. Human a1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by a1?1 integrin. J Clin Invest. 2020 01 02; 130(1):552. PMID: 31895054; PMCID: PMC6934208.
      Citations: 1     Fields:    
    59. Suhail Y, Cain MP, Vanaja K, Kurywchak PA, Levchenko A, Kalluri R. Systems Biology of Cancer Metastasis. Cell Syst. 2019 08 28; 9(2):109-127. PMID: 31465728; PMCID: PMC6716621.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    60. McAndrews KM, LeBleu VS, Kalluri R. SIRT1 Regulates Lysosome Function and Exosome Secretion. Dev Cell. 2019 05 06; 49(3):302-303. PMID: 31063745.
      Citations: 8     Fields:    Translation:HumansCells
    61. McAndrews KM, Kalluri R. Nischarin Regulates Secretion of Exosomes and Cancer Progression. Cancer Res. 2019 05 01; 79(9):2099-2101. PMID: 31043427.
      Citations: 1     Fields:    Translation:HumansCells
    62. McAndrews KM, Kalluri R. Mechanisms associated with biogenesis of exosomes in cancer. Mol Cancer. 2019 03 30; 18(1):52. PMID: 30925917; PMCID: PMC6441149.
      Citations: 104     Fields:    Translation:HumansAnimalsCells
    63. LeBleu VS, Kalluri R. Exosomes Exercise Inhibition of Anti-Tumor Immunity during Chemotherapy. Immunity. 2019 03 19; 50(3):547-549. PMID: 30893584.
      Citations: 13     Fields:    Translation:HumansCells
    64. Chen Y, Keskin D, Sugimoto H, Kanasaki K, Phillips PE, Bizarro L, Sharpe A, LeBleu VS, Kalluri R. Podoplanin+ tumor lymphatics are rate limiting for breast cancer metastasis. PLoS Biol. 2018 12; 16(12):e2005907. PMID: 30592710; PMCID: PMC6310240.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    65. Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Antoniou A, Archer F, Atkin-Smith GK, Ayre DC, Bachurski D, Baharvand H, Balaj L, Baldacchino S, Bauer NN, Baxter AA, Bebawy M, Beckham C, Bedina Zavec A, Berardi AC, Bergese P, Bielska E, Blenkiron C, Bongiovanni A, Boulanger CM, Breakefield X, Breglio AM, Brigstock DR, Broekman ML, Bromberg JF, Buch S, Buck AH, Burger D, Busatto S, Buschmann D, Bussolati B, Byrd JB, Camussi G, Carter DR, Caruso S, Chamley LW, Chang YT, Chen C, Chen S, Cheng L, Chin AR, Clayton A, Clerici SP, Cocks A, Cocucci E, Coffey RJ, Cordeiro-da-Silva A, Couch Y, Coumans FA, Coyle B, Crescitelli R, D'Souza-Schorey C, Das S, Datta Chaudhuri A, de Candia P, De Wever O, Deville S, Devitt A, Dhondt B, Di Vizio D, Dieterich LC, Dolo V, Dominici M, Dourado MR, Driedonks TA, Duarte FV, Duncan HM, Eichenberger RM, El Andaloussi S, Fish JE, Flores-Bellver M, Fricke F, Fuhrmann G, Gabrielsson S, Gardiner C, Gaudin R, Gho YS, Giebel B, Gimona M, Giusti I, Goberdhan DC, Gorski SM, Greening DW, Gualerzi A, Gupta GN, Gustafson D, Handberg A, Haraszti RA, Harrison P, Hegyesi H, Hendrix A, Hill AF, Hochberg FH, Hoffmann KF, Holder B, Holthofer H, Hosseinkhani B, Hu G, Huang Y, Huber V, Hunt S, Ibrahim AG, Ikezu T, Inal JM, Isin M, Ivanova A, Jackson HK, Jacobsen S, Jay SM, Jayachandran M, Jenster G, Jiang L, Johnson SM, Jones JC, Jong A, Jovanovic-Talisman T, Jung S, Kalluri R, Kano SI, Kaur S, Kawamura Y, Keller ET, Khamari D, Khvorova A, Kierulf P, Kim KP, Kislinger T, Klingeborn M, Klinke DJ, Kornek M, Kosanovic MM, Krasemann S, Krause M, Kurochkin IV, Kusuma GD, Laitinen S, Langevin SM, Languino LR, Lannigan J, Laurent LC, Lavieu G, Lee MS, Lee YXF, Lenassi M, Leszczynska A, Li IT, Liao K, Libregts SF, Ligeti E, Lim R, Lim SK, Line A, Llorente A, Lorenowicz MJ, Lovett J, Lowry MC, Loyer X, Lu Q, Lukomska B, Lunavat TR, Maas SL, Malhi H, Mariscal J, Martens-Uzunova ES, Martin-Jaular L, Mathieu M, Mathivanan S, Maugeri M, McGinnis LK, McVey MJ, Meckes DG, Meehan KL, Mertens I, Minciacchi VR, Morales-Kastresana A, Morhayim J, Muraca M, Musante L, Mussack V, Muth DC, Myburgh KH, Najrana T, Nawaz M, Nazarenko I, Nejsum P, Neri T, Nieuwland R, Nimrichter L, Nolan JP, Nolte-'t Hoen EN, Noren Hooten N, O'Driscoll L, O'Loghlen A, Ochiya T, Olivier M, Ortiz A, Ortiz LA, Osteikoetxea X, Park J, Pegtel DM, Peinado H, Perut F, Pfaffl MW, Phinney DG, Pieters BC, Pink RC, Pisetsky DS, Pogge von Strandmann E, Poon IK, Powell BH, Prada I, Pulliam L, Quesenberry P, Radeghieri A, Raffai RL, Raimondo S, Rak J, Ramirez MI, Rayyan MS, Regev-Rudzki N, Ricklefs FL, Robbins PD, Roberts DD, Rodrigues SC, Rohde E, Rouschop KM, Rughetti A, Russell AE, Sahoo S, Salas-Huenuleo E, Saugstad JA, Schiffelers RM, Schneider R, Scott A, Shahaj E, Sharma S, Shatnyeva O, Shekari F, Shelke GV, Shetty AK, Shiba K, Siljander PR, Skowronek A, Snyder OL, Soekmadji C, Sotillo J, Stahl PD, Stoorvogel W, Stott SL, Strasser EF, Swift S, Tahara H, Tewari M, Timms K, Tiwari S, Tixeira R, Tkach M, Toh WS, Tomasini R, Tosar JP, Toxavidis V, Urbanelli L, Vader P, van Balkom BW, van der Grein SG, Van Deun J, van Herwijnen MJ, Van Keuren-Jensen K, van Niel G, van Royen ME, van Wijnen AJ, Vasconcelos MH, Vechetti IJ, Vella LJ, Verweij FJ, Vestad B, Vukman KV, Watson DC, Wauben MH, Weaver A, Webber JP, Weber V, Weiss DJ, Welsh JA, Wendt S, Wheelock AM, Wolfram J, Xagorari A, Xu J, Yan X, Yin H, Yuana Y, Zappulli V, Zarubova J, Zhang JY, Zhao Z, Zheng L, Zheutlin AR, Zickler AM, Zivkovic AM, Zocco D, Th?ry C, Andriantsitohaina R, Arab T, Bach JM, Benmoussa A, Bobis-Wozowicz S, Boilard E, Boireau W, Borr?s FE, Bosch S, Brennan M?, Brisson A, Bryl-G?recka P, Buz?s EI, Criado MF, De Santana EF, Del Portillo HA, Demaret T, Dominguez Rubio AP, Ekstr?m K, Elie-Caille C, Erdbr?gger U, Falc?n-P?rez JM, Fatima F, F?rs?nits A, Frelet-Barrand A, G?mez-Valero A, G?rtner K, Gilbert C, G?rgens A, Gross JC, Khomyakova E, Kov?cs ?F, Kr?mer-Albers EM, Kuypers S, L?sser C, et al. Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines. J Extracell Vesicles. 2018; 7(1):1535750. PMID: 30637094; PMCID: PMC6322352.
      Citations: 2679     Fields:    
    66. Parchem JG, Kanasaki K, Kanasaki M, Sugimoto H, Xie L, Hamano Y, Lee SB, Gattone VH, Parry S, Strauss JF, Garovic VD, McElrath TF, Lu KH, Sibai BM, LeBleu VS, Carmeliet P, Kalluri R. Loss of placental growth factor ameliorates maternal hypertension and preeclampsia in mice. J Clin Invest. 2018 11 01; 128(11):5008-5017. PMID: 30179860; PMCID: PMC6205389.
      Citations: 12     Fields:    Translation:Animals
    67. Chen Y, LeBleu VS, Carstens JL, Sugimoto H, Zheng X, Malasi S, Kalluri R, Saur D. Dual reporter genetic mouse models of pancreatic cancer identify an epithelial-to-mesenchymal transition-independent metastasis program. EMBO Mol Med. 2018 10; 10(10). PMID: 30120146; PMCID: PMC6180301.
      Citations: 32     Fields:    Translation:Animals
    68. Kalluri R, Xu X, Tan X, Tampe B, Wilhelmi T, Hulshoff MS, Saito S, Moser T, Hasenfuss G, Zeisberg EM, Zeisberg M. High-fidelity CRISPR/Cas9- based gene-specific hydroxymethylation rescues gene expression and attenuates renal fibrosis. Nat Commun. 2018 08 29; 9(1):3509. PMID: 30158531; PMCID: PMC6115451.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    69. Nowak-Sliwinska P, Alitalo K, Allen E, Anisimov A, Aplin AC, Auerbach R, Augustin HG, Bates DO, van Beijnum JR, Bender RHF, Bergers G, Bikfalvi A, Bischoff J, Brooks PC, Bussolino F, Cakir B, Carmeliet P, Castranova D, Cimpean AM, Cleaver O, Coukos G, Davis GE, De Palma M, Dimberg A, Dings RPM, Djonov V, Dudley AC, Dufton NP, Fendt SM, Ferrara N, Fruttiger M, Fukumura D, Gong Y, Griffin RJ, Harris AL, Hughes CCW, Hultgren NW, Iruela-Arispe ML, Irving M, Jain RK, Kalluri R, Kalucka J, Kerbel RS, Kitajewski J, Klaassen I, Kleinmann HK, Koolwijk P, Kuczynski E, Kwak BR, Marien K, Melero-Martin JM, Munn LL, Nicosia RF, Nurro J, Olsson AK, Petrova TV, Pietras K, Pili R, Pollard JW, Post MJ, Quax PHA, Rabinovich GA, Raica M, Randi AM, Ribatti D, Ruegg C, Schlingemann RO, Smith LEH, Song JW, Stacker SA, Stratman AN, van Hinsbergh VWM, Vermeulen PB, Weinstein BM, Xin H, Yetkin-Arik B, Yla-Herttuala S, Yoder MC, Griffioen AW, B?ck BC, Ghesqui?re B, Noel A, Schulte-Merker S, Stalin J, Van de Velde M, Waltenberger J. Consensus guidelines for the use and interpretation of angiogenesis assays. Angiogenesis. 2018 08; 21(3):425-532. PMID: 29766399; PMCID: PMC6237663.
      Citations: 209     Fields:    Translation:HumansAnimals
    70. Eikesdal HP, Becker LM, Teng Y, Kizu A, Carstens JL, Kanasaki K, Sugimoto H, LeBleu VS, Kalluri R. BMP7 Signaling in TGFBR2-Deficient Stromal Cells Provokes Epithelial Carcinogenesis. Mol Cancer Res. 2018 10; 16(10):1568-1578. PMID: 29934328; PMCID: PMC6170697.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    71. Nyamsuren G, Rapp G, Kauffels A, Lorf T, Kalluri R, Zeisberg M, Tampe B, Tampe D, Kl?pper F, Zeisberg EM, M?ller GA, Hakroush S. Pharmacological induction of hypoxia-inducible transcription factor ARNT attenuates chronic kidney failure. J Clin Invest. 2018 07 02; 128(7):3053-3070. PMID: 29664738; PMCID: PMC6025987.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    72. LeBleu VS, Kalluri R. A peek into cancer-associated fibroblasts: origins, functions and translational impact. Dis Model Mech. 2018 04 19; 11(4). PMID: 29686035; PMCID: PMC5963854.
      Citations: 173     Fields:    Translation:HumansAnimalsCells
    73. Mendt M, Kamerkar S, Sugimoto H, McAndrews KM, Wu CC, Gagea M, Yang S, Blanko EVR, Peng Q, Ma X, Marszalek JR, Maitra A, Yee C, Rezvani K, Shpall E, LeBleu VS, Kalluri R. Generation and testing of clinical-grade exosomes for pancreatic cancer. JCI Insight. 2018 04 19; 3(8). PMID: 29669940; PMCID: PMC5931131.
      Citations: 203     Fields:    Translation:AnimalsCells
    74. Kurywchak P, Tavormina J, Kalluri R. The emerging roles of exosomes in the modulation of immune responses in cancer. Genome Med. 2018 03 26; 10(1):23. PMID: 29580275; PMCID: PMC5868069.
      Citations: 43     Fields:    Translation:HumansCells
    75. Lovisa S, Kalluri R. Fatty Acid Oxidation Regulates the Activation of Endothelial-to-Mesenchymal Transition. Trends Mol Med. 2018 05; 24(5):432-434. PMID: 29573973.
      Citations: 10     Fields:    Translation:Cells
    76. Gabrusiewicz K, Li X, Wei J, Hashimoto Y, Marisetty AL, Ott M, Wang F, Hawke D, Yu J, Healy LM, Hossain A, Akers JC, Maiti SN, Yamashita S, Shimizu Y, Dunner K, Zal MA, Burks JK, Gumin J, Nwajei F, Rezavanian A, Zhou S, Rao G, Sawaya R, Fuller GN, Huse JT, Antel JP, Li S, Cooper L, Sulman EP, Chen C, Geula C, Kalluri R, Zal T, Heimberger AB. Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes. Oncoimmunology. 2018; 7(4):e1412909. PMID: 29632728; PMCID: PMC5889290.
      Citations: 122     Fields:    
    77. Kalluri R, Weinberg RA, Brabletz T, Nieto MA. EMT in cancer. Nat Rev Cancer. 2018 02; 18(2):128-134. PMID: 29326430.
      Citations: 649     Fields:    Translation:Humans
    78. Jiao J, Stevenson HL, Gagea M, Sugimoto H, Kalluri R, Beretta L, Gonz?lez ?. Depletion of S100A4+ stromal cells does not prevent HCC development but reduces the stem cell-like phenotype of the tumors. Exp Mol Med. 2018 01 05; 50(1):e422. PMID: 29303514; PMCID: PMC5992984.
      Citations: 10     Fields:    Translation:AnimalsCells
    79. Figueroa J, Phillips LM, Shahar T, Hossain A, Gumin J, Kim H, Bean AJ, Calin GA, Fueyo J, Walters ET, Kalluri R, Verhaak RG, Lang FF. Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587. Cancer Res. 2017 11 01; 77(21):5808-5819. PMID: 28855213; PMCID: PMC5668150.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    80. Pickup MW, Owens P, Gorska AE, Chytil A, Ye F, Shi C, Weaver VM, Kalluri R, Moses HL, Novitskiy SV. Development of Aggressive Pancreatic Ductal Adenocarcinomas Depends on Granulocyte Colony Stimulating Factor Secretion in Carcinoma Cells. Cancer Immunol Res. 2017 09; 5(9):718-729. PMID: 28775207; PMCID: PMC5581681.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    81. Kamerkar S, LeBleu VS, Sugimoto H, Yang S, Melo SA, Lee JJ, Kalluri R, Ruivo CF. Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer. Nature. 2017 06 22; 546(7659):498-503. PMID: 28607485; PMCID: PMC5538883.
      Citations: 667     Fields:    Translation:AnimalsCells
    82. Kurywchak P, Kalluri R. An evolving function of DNA-containing exosomes in chemotherapy-induced immune response. Cell Res. 2017 Jun; 27(6):722-723. PMID: 28524163; PMCID: PMC5518880.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    83. Carstens JL, Correa de Sampaio P, Yang D, Barua S, Wang H, Rao A, Allison JP, LeBleu VS, Kalluri R. Spatial computation of intratumoral T cells correlates with survival of patients with pancreatic cancer. Nat Commun. 2017 04 27; 8:15095. PMID: 28447602; PMCID: PMC5414182.
      Citations: 191     Fields:    Translation:HumansAnimalsCells
    84. Kalluri R, LeBleu VS. Discovery of Double-Stranded Genomic DNA in Circulating Exosomes. Cold Spring Harb Symp Quant Biol. 2016; 81:275-280. PMID: 28424339.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    85. Yang S, Che SP, Kurywchak P, Tavormina JL, Gansmo LB, Correa de Sampaio P, Tachezy M, Bockhorn M, Gebauer F, Haltom AR, LeBleu VS, Kalluri R, Melo SA. Detection of mutant KRAS and TP53 DNA in circulating exosomes from healthy individuals and patients with pancreatic cancer. Cancer Biol Ther. 2017 03 04; 18(3):158-165. PMID: 28121262; PMCID: PMC5389423.
      Citations: 83     Fields:    Translation:HumansCells
    86. Carstens JL, Kalluri R, Tampe B, Steinle U, Tampe D, Korsten P, Zeisberg EM, M?ller GA, Zeisberg M. Low-dose hydralazine prevents fibrosis in a murine model of acute kidney injury-to-chronic kidney disease progression. Kidney Int. 2017 01; 91(1):157-176. PMID: 27692563.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    87. Kalluri R. The biology and function of fibroblasts in cancer. Nat Rev Cancer. 2016 08 23; 16(9):582-98. PMID: 27550820.
      Citations: 1253     Fields:    Translation:HumansCells
    88. Lovisa S, Kalluri R, Zeisberg M. Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis. Trends Endocrinol Metab. 2016 10; 27(10):681-695. PMID: 27372267.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    89. Laklai H, Miroshnikova YA, Pickup MW, Collisson EA, Kim GE, Barrett AS, Hill RC, Lakins JN, Schlaepfer DD, Mouw JK, LeBleu VS, Roy N, Novitskiy SV, Johansen JS, Poli V, Kalluri R, Iacobuzio-Donahue CA, Wood LD, Hebrok M, Hansen K, Moses HL, Weaver VM. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nat Med. 2016 05; 22(5):497-505. PMID: 27089513; PMCID: PMC4860133.
      Citations: 240     Fields:    Translation:HumansAnimalsCells
    90. Kalluri R. The biology and function of exosomes in cancer. J Clin Invest. 2016 Apr 01; 126(4):1208-15. PMID: 27035812; PMCID: PMC4811149.
      Citations: 618     Fields:    Translation:HumansAnimalsCells
    91. Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Sugimoto H, Kahlert C, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Maitra A, Allison JP, LeBleu VS, Kalluri R, ?zdemir BC. Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival. Cancer Cell. 2015 Dec 14; 28(6):831-833. PMID: 28843279.
      Citations: 74     Fields:    
    92. Cleland TP, Schroeter ER, Zamdborg L, Zheng W, Lee JE, Tran JC, Bern M, Duncan MB, Lebleu VS, Ahlf DR, Thomas PM, Kalluri R, Kelleher NL, Schweitzer MH. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. J Proteome Res. 2015 Dec 04; 14(12):5252-62. PMID: 26595531; PMCID: PMC4768904.
      Citations: 22     Fields:    Translation:AnimalsCells
    93. Zheng X, Carstens JL, Kim J, Scheible M, Kaye J, Sugimoto H, Wu CC, LeBleu VS, Kalluri R. Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer. Nature. 2015 Nov 26; 527(7579):525-530. PMID: 26560028; PMCID: PMC4849281.
      Citations: 972     Fields:    Translation:Animals
    94. Lovisa S, LeBleu VS, Sugimoto H, Vadnagara K, Carstens JL, Wu CC, Pentcheva-Hoang T, Nischal H, Allison JP, Kalluri R, Tampe B, Hagos Y, Burckhardt BC, Zeisberg M. Epithelial-to-mesenchymal transition induces cell cycle arrest and parenchymal damage in renal fibrosis. Nat Med. 2015 Sep; 21(9):998-1009. PMID: 26236991; PMCID: PMC4587560.
      Citations: 322     Fields:    Translation:HumansAnimalsCells
    95. Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, LeBleu VS, Mittendorf EA, Fraga MF, Piwnica-Worms D, Kalluri R, Weitz J, Rahbari N, Reissfelder C, Pilarsky C. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature. 2015 Jul 09; 523(7559):177-82. PMID: 26106858; PMCID: PMC4825698.
      Citations: 969     Fields:    Translation:HumansAnimalsCells
    96. Melo CA, Rooijers K, Melo SA, Korkmaz G, Lopes R, Moqadam FA, Maia AR, Wijchers PJ, Geeven G, den Boer ML, Kalluri R, de Laat W, Esteller M, Agami R, L?veill? N, D?az-Lagares A. Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA. Nat Commun. 2015 Mar 27; 6:6520. PMID: 25813522; PMCID: PMC4389233.
      Citations: 99     Fields:    Translation:HumansCells
    97. Kalluri R, Zeisberg M. Physiology of the Renal Interstitium. Clin J Am Soc Nephrol. 2015 Oct 07; 10(10):1831-40. PMID: 25813241; PMCID: PMC4594057.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    98. Zhang J, Jiao J, Cermelli S, Muir K, Jung KH, Zou R, Rashid A, Gagea M, Zabludoff S, Kalluri R, Beretta L. miR-21 Inhibition Reduces Liver Fibrosis and Prevents Tumor Development by Inducing Apoptosis of CD24+ Progenitor Cells. Cancer Res. 2015 May 01; 75(9):1859-67. PMID: 25769721; PMCID: PMC4603420.
      Citations: 35     Fields:    Translation:AnimalsCells
    99. Keskin D, Kim J, Cooke VG, Wu CC, Sugimoto H, Gu C, Kalluri R, LeBleu VS, De Palma M. Targeting vascular pericytes in hypoxic tumors increases lung metastasis via angiopoietin-2. Cell Rep. 2015 Feb 24; 10(7):1066-81. PMID: 25704811; PMCID: PMC4342328.
      Citations: 72     Fields:    Translation:AnimalsCells
    100. Maier LS, Kalluri R, Xu X, Tan X, Tampe B, Nyamsuren G, Liu X, Sossalla S, Zeisberg M, Hasenfuss G, Zeisberg EM. Epigenetic balance of aberrant Rasal1 promoter methylation and hydroxymethylation regulates cardiac fibrosis. Cardiovasc Res. 2015 Mar 01; 105(3):279-91. PMID: 25616414.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    101. Xu X, Friehs I, Zhong Hu T, Melnychenko I, Tampe B, Alnour F, Iascone M, Kalluri R, Zeisberg M, Del Nido PJ, Zeisberg EM. Endocardial fibroelastosis is caused by aberrant endothelial to mesenchymal transition. Circ Res. 2015 Feb 27; 116(5):857-66. PMID: 25587097; PMCID: PMC4344885.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    102. Bechtel-Walz W, Kalluri R, Tampe B, Tampe D, Zeisberg EM, M?ller GA, Koziolek M, Zeisberg M. Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease. EBioMedicine. 2015 Jan; 2(1):19-36. PMID: 25717475; PMCID: PMC4337426.
      Citations: 26     Fields:    
    103. Melo SA, Sugimoto H, O'Connell JT, Kato N, Villanueva A, Vidal A, Qiu L, Vitkin E, Perelman LT, Melo CA, Lucci A, Ivan C, Calin GA, Kalluri R. Cancer exosomes perform cell-independent microRNA biogenesis and promote tumorigenesis. Cancer Cell. 2014 Nov 10; 26(5):707-21. PMID: 25446899; PMCID: PMC4254633.
      Citations: 675     Fields:    Translation:HumansAnimalsCells
    104. Miyake T, Kalluri R. Cardiac biology: Cell plasticity helps hearts to repair. Nature. 2014 Oct 30; 514(7524):575-6. PMID: 25317554.
      Citations: 5     Fields:    Translation:AnimalsCells
    105. LeBleu VS, O'Connell JT, Gonzalez Herrera KN, Wikman H, Pantel K, Haigis MC, de Carvalho FM, Damascena A, Domingos Chinen LT, Rocha RM, Asara JM, Kalluri R. PGC-1a mediates mitochondrial biogenesis and oxidative phosphorylation in cancer cells to promote?metastasis. Nat Cell Biol. 2014 Oct; 16(10):992-1003, 1-15. PMID: 25241037; PMCID: PMC4369153.
      Citations: 558     Fields:    Translation:HumansAnimalsCells
    106. LeBleu V, Kalluri R, Zeisberg M, Tampe B, Tampe D, Zeisberg EM. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. Am J Pathol. 2014 Oct; 184(10):2687-98. PMID: 25111226; PMCID: PMC4715225.
      Citations: 12     Fields:    Translation:Animals
    107. Charytan DM, Padera R, Helfand AM, Himmelfarb J, Cinelli A, Kalluri R, Zeisberg M, Xu X, Liu X, Zeisberg EM. Increased concentration of circulating angiogenesis and nitric oxide inhibitors induces endothelial to mesenchymal transition and myocardial fibrosis in patients with chronic kidney disease. Int J Cardiol. 2014 Sep; 176(1):99-109. PMID: 25049013; PMCID: PMC4161362.
      Citations: 41     Fields:    Translation:HumansCells
    108. Pentcheva-Hoang T, Carstens JL, Zheng X, Wu CC, Simpson TR, Laklai H, Novitskiy SV, De Jesus-Acosta A, Sharma P, Heidari P, Mahmood U, Chin L, Moses HL, Weaver VM, Allison JP, ?zdemir BC, Sugimoto H, Kahlert C, Maitra A, LeBleu VS, Kalluri R. Depletion of carcinoma-associated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014 Jun 16; 25(6):719-34. PMID: 24856586; PMCID: PMC4180632.
      Citations: 944     Fields:    Translation:HumansAnimalsCells
    109. Kanasaki K, Kanasaki M, Vong S, Rovira C, Kalluri R, Ayala de la Pe?a F. Specific activation of K-RasG12D allele in the bladder urothelium results in lung alveolar and vascular defects. PLoS One. 2014; 9(4):e95888. PMID: 24760005; PMCID: PMC3997426.
      Citations: 1     Fields:    Translation:Animals
    110. Carstens JL, Lovisa S, Kalluri R. Microenvironment-dependent cues trigger miRNA-regulated feedback loop to facilitate the EMT/MET switch. J Clin Invest. 2014 Apr; 124(4):1458-60. PMID: 24642461; PMCID: PMC3973103.
      Citations: 19     Fields:    Translation:HumansAnimals
    111. Tampe D, Sugimoto H, LeBleu V, Kalluri R, Zeisberg M, Tampe B, M?ller CA, Xu X, M?ller GA, Zeisberg EM. Tet3-mediated hydroxymethylation of epigenetically silenced genes contributes to bone morphogenic protein 7-induced reversal of kidney fibrosis. J Am Soc Nephrol. 2014 May; 25(5):905-12. PMID: 24480825; PMCID: PMC4005308.
      Citations: 56     Fields:    Translation:AnimalsCells
    112. Kahlert C, Melo SA, Protopopov A, Tang J, Seth S, Koch M, Zhang J, Weitz J, Chin L, Futreal A, Kalluri R. Identification of double-stranded genomic DNA spanning all chromosomes with mutated KRAS and p53 DNA in the serum exosomes of patients with pancreatic cancer. J Biol Chem. 2014 Feb 14; 289(7):3869-75. PMID: 24398677; PMCID: PMC3924256.
      Citations: 418     Fields:    Translation:HumansCellsCTClinical Trials
    113. Atala A. Re: Loss of ?1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype. J Urol. 2013 Dec; 190(6):2305. PMID: 24209569.
      Citations:    Fields:    Translation:AnimalsCells
    114. Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe D, Kanasaki K, Zeisberg M, Kalluri R, Tampe B. Reply to Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nat Med. 2013 Jul; 19(7):810-1. PMID: 23836214.
      Citations: 2     Fields:    Translation:Animals
    115. LeBleu VS, Taduri G, O'Connell J, Teng Y, Cooke VG, Woda C, Sugimoto H, Kalluri R. Origin and function of myofibroblasts in kidney fibrosis. Nat Med. 2013 Aug; 19(8):1047-53. PMID: 23817022; PMCID: PMC4067127.
      Citations: 525     Fields:    Translation:AnimalsCells
    116. Plaks V, Rinkenberger J, Dai J, Flannery M, Sund M, Kanasaki K, Ni W, Kalluri R, Werb Z. Matrix metalloproteinase-9 deficiency phenocopies features of preeclampsia and intrauterine growth restriction. Proc Natl Acad Sci U S A. 2013 Jul 02; 110(27):11109-14. PMID: 23776237; PMCID: PMC3704020.
      Citations: 72     Fields:    Translation:HumansAnimals
    117. Zeisberg M, Kalluri R. The Kielin/chordin-like protein checkpoint constitutes a system of checks and balances in CKD. J Am Soc Nephrol. 2013 May; 24(6):863-5. PMID: 23687357.
      Citations: 1     Fields:    Translation:AnimalsCells
    118. Duncan MB, Yang C, Tanjore H, Boyle PM, Keskin D, Sugimoto H, Zeisberg M, Olsen BR, Kalluri R. Type XVIII collagen is essential for survival during acute liver injury in mice. Dis Model Mech. 2013 Jul; 6(4):942-51. PMID: 23580202; PMCID: PMC3701214.
      Citations: 9     Fields:    Translation:AnimalsCells
    119. Kahlert C, Kalluri R. Exosomes in tumor microenvironment influence cancer progression and metastasis. J Mol Med (Berl). 2013 Apr; 91(4):431-7. PMID: 23519402; PMCID: PMC4073669.
      Citations: 343     Fields:    Translation:HumansAnimalsCells
    120. Andersen DC, Schneider M, Sandberg MB, Eskildsen T, Nielsen SB, Kalluri R, Br?nnum H, Sheikh SP. miR-21 promotes fibrogenic epithelial-to-mesenchymal transition of epicardial mesothelial cells involving Programmed Cell Death 4 and Sprouty-1. PLoS One. 2013; 8(2):e56280. PMID: 23441172; PMCID: PMC3575372.
      Citations: 39     Fields:    Translation:Humans
    121. Kanasaki K, Yu W, von Bodungen M, Larigakis JD, Kanasaki M, Ayala de la Pena F, Kalluri R, Hill WG. Loss of ?1-integrin from urothelium results in overactive bladder and incontinence in mice: a mechanosensory rather than structural phenotype. FASEB J. 2013 May; 27(5):1950-61. PMID: 23395910; PMCID: PMC3633821.
      Citations: 24     Fields:    Translation:AnimalsCells
    122. Melo SA, Kalluri R. miR-29b moulds the tumour microenvironment to repress metastasis. Nat Cell Biol. 2013 Feb; 15(2):139-40. PMID: 23377028.
      Citations: 23     Fields:    Translation:HumansAnimals
    123. LeBleu VS, Teng Y, O'Connell JT, Charytan D, Sugimoto H, Kalluri R, M?ller GA, M?ller CA. Identification of human epididymis protein-4 as a fibroblast-derived mediator of fibrosis. Nat Med. 2013 Feb; 19(2):227-31. PMID: 23353556; PMCID: PMC4457508.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    124. Borges FT, Melo SA, Kato N, Revuelta I, Miller CA, Gattone VH, LeBleu VS, Kalluri R, ?zdemir BC. TGF-?1-containing exosomes from injured epithelial cells activate fibroblasts to initiate tissue regenerative responses and fibrosis. J Am Soc Nephrol. 2013 Feb; 24(3):385-92. PMID: 23274427; PMCID: PMC3582210.
      Citations: 172     Fields:    Translation:HumansAnimalsCells
    125. Melo CA, Drost J, Wijchers PJ, van de Werken H, de Wit E, Oude Vrielink JA, Elkon R, Kalluri R, de Laat W, Agami R, Melo SA, L?veill? N. eRNAs are required for p53-dependent enhancer activity and gene transcription. Mol Cell. 2013 Feb 07; 49(3):524-35. PMID: 23273978.
      Citations: 299     Fields:    Translation:HumansCells
    126. Kalluri R, Zeisberg M. Cellular mechanisms of tissue fibrosis. 1. Common and organ-specific mechanisms associated with tissue fibrosis. Am J Physiol Cell Physiol. 2013 Feb 01; 304(3):C216-25. PMID: 23255577; PMCID: PMC3566435.
      Citations: 157     Fields:    Translation:HumansAnimals
    127. Kieran MW, Kalluri R, Cho YJ. The VEGF pathway in cancer and disease: responses, resistance, and the path forward. Cold Spring Harb Perspect Med. 2012 Dec 01; 2(12):a006593. PMID: 23209176; PMCID: PMC3543071.
      Citations: 81     Fields:    Translation:HumansCells
    128. Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W. Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26; 2(1):52-61. PMID: 22840396; PMCID: PMC3627357.
      Citations: 30     Fields:    Translation:AnimalsCells
    129. Melo SA, Kalluri R. Molecular pathways: microRNAs as cancer therapeutics. Clin Cancer Res. 2012 Aug 15; 18(16):4234-9. PMID: 22711704; PMCID: PMC4041567.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    130. Medici D, Kalluri R. Endothelial-mesenchymal transition and its contribution to the emergence of stem cell phenotype. Semin Cancer Biol. 2012 Oct; 22(5-6):379-84. PMID: 22554794; PMCID: PMC3422405.
      Citations: 98     Fields:    Translation:HumansAnimalsCells
    131. Melo SA, Kalluri R. Angiogenesis is controlled by miR-27b associated with endothelial tip cells. Blood. 2012 Mar 15; 119(11):2439-40. PMID: 22422815.
      Citations: 6     Fields:    
    132. Sugimoto H, LeBleu VS, Bosukonda D, Keck P, Taduri G, Bechtel W, Okada H, Carlson W, Bey P, Rusckowski M, Tampe D, Kanasaki K, Zeisberg M, Kalluri R, Tampe B. Activin-like kinase 3 is important for kidney regeneration and reversal of fibrosis. Nat Med. 2012 Feb 05; 18(3):396-404. PMID: 22306733; PMCID: PMC3998727.
      Citations: 109     Fields:    Translation:AnimalsCells
    133. Cooke VG, LeBleu VS, Keskin D, Khan Z, O'Connell JT, Teng Y, Duncan MB, Xie L, Maeda G, Vong S, Sugimoto H, Rocha RM, Damascena A, Brentani RR, Kalluri R. Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012 Jan 17; 21(1):66-81. PMID: 22264789; PMCID: PMC3999522.
      Citations: 229     Fields:    Translation:HumansAnimalsCells
    134. Ho DN, Kohler N, Sigdel A, Kalluri R, Morgan JR, Xu C, Sun S. Penetration of endothelial cell coated multicellular tumor spheroids by iron oxide nanoparticles. Theranostics. 2012; 2(1):66-75. PMID: 22272220; PMCID: PMC3263517.
      Citations: 13     Fields:    
    135. LeBleu VS, Kalluri R. Blockade of PDGF receptor signaling reduces myofibroblast number and attenuates renal fibrosis. Kidney Int. 2011 Dec; 80(11):1119-21. PMID: 22083636; PMCID: PMC4316679.
      Citations: 13     Fields:    Translation:AnimalsCells
    136. Vong S, Kalluri R. The role of stromal myofibroblast and extracellular matrix in tumor angiogenesis. Genes Cancer. 2011 Dec; 2(12):1139-45. PMID: 22866205; PMCID: PMC3411128.
      Citations: 54     
    137. De Raedt T, Walton Z, Yecies JL, Li D, Chen Y, Malone CF, Jeong SM, Bronson RT, Lebleu V, Kalluri R, Normant E, Haigis MC, Manning BD, Wong KK, Macleod KF, Cichowski K, Maertens O. Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. Cancer Cell. 2011 Sep 13; 20(3):400-13. PMID: 21907929; PMCID: PMC3233475.
      Citations: 130     Fields:    Translation:AnimalsCells
    138. O'Connell JT, Sugimoto H, Cooke VG, MacDonald BA, Mehta AI, LeBleu VS, Dewar R, Rocha RM, Brentani RR, Resnick MB, Neilson EG, Zeisberg M, Kalluri R. VEGF-A and Tenascin-C produced by S100A4+ stromal cells are important for metastatic colonization. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):16002-7. PMID: 21911392; PMCID: PMC3179047.
      Citations: 150     Fields:    Translation:HumansAnimalsCells
    139. Charytan DM, Helfand AM, MacDonald BA, Cinelli A, Kalluri R, Zeisberg EM. Circulating endoglin concentration is not elevated in chronic kidney disease. PLoS One. 2011; 6(8):e23718. PMID: 21886815; PMCID: PMC3158786.
      Citations: 4     Fields:    Translation:Humans
    140. Medici D, Potenta S, Kalluri R. Transforming growth factor-?2 promotes Snail-mediated endothelial-mesenchymal transition through convergence of Smad-dependent and Smad-independent signalling. Biochem J. 2011 Aug 01; 437(3):515-20. PMID: 21585337; PMCID: PMC4457510.
      Citations: 144     Fields:    Translation:HumansCells
    141. Tse JC, Kalluri R. Waking up dormant tumors. Breast Cancer Res. 2011 Jun 10; 13(3):310. PMID: 21672272; PMCID: PMC3218930.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    142. San Antonio JD, Schweitzer MH, Jensen ST, Kalluri R, Buckley M, Orgel JP. Dinosaur peptides suggest mechanisms of protein survival. PLoS One. 2011; 6(6):e20381. PMID: 21687667; PMCID: PMC3110760.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    143. Xie L, Duncan MB, Pahler J, Sugimoto H, Martino M, Lively J, Mundel T, Soubasakos M, Rubin K, Takeda T, Inoue M, Lawler J, Hynes RO, Hanahan D, Kalluri R. Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner. Proc Natl Acad Sci U S A. 2011 Jun 14; 108(24):9939-44. PMID: 21622854; PMCID: PMC3116421.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    144. Kanasaki K, Kanasaki M, Tangirala N, Maeda G, Kalluri R, Ayala de la Pe?a F. Loss of p53 and acquisition of angiogenic microRNA profile are insufficient to facilitate progression of bladder urothelial carcinoma in situ to invasive carcinoma. J Biol Chem. 2011 Jun 10; 286(23):20778-87. PMID: 21388952; PMCID: PMC3121487.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    145. Teng Y, Kanasaki K, Bardeesy N, Sugimoto H, Kalluri R. Deletion of Smad4 in fibroblasts leads to defective chondrocyte maturation and cartilage production in a TGF? type II receptor independent manner. Biochem Biophys Res Commun. 2011 Apr 22; 407(4):633-9. PMID: 21376704; PMCID: PMC3999521.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    146. Melo S, Villanueva A, Moutinho C, Davalos V, Spizzo R, Ivan C, Rossi S, Setien F, Casanovas O, Simo-Riudalbas L, Carmona J, Carrere J, Vidal A, Aytes A, Puertas S, Ropero S, Kalluri R, Croce CM, Calin GA, Esteller M. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc Natl Acad Sci U S A. 2011 Mar 15; 108(11):4394-9. PMID: 21368194; PMCID: PMC3060242.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    147. Bravo-Nuevo A, Sugimoto H, Iyer S, Fallon Z, Lucas JM, Kazerounian S, Prendergast GC, Kalluri R, Shapiro NI, Benjamin LE. RhoB loss prevents streptozotocin-induced diabetes and ameliorates diabetic complications in mice. Am J Pathol. 2011 Jan; 178(1):245-52. PMID: 21224061; PMCID: PMC3069827.
      Citations: 8     Fields:    Translation:AnimalsCells
    148. Lee SB, Kalluri R. Mechanistic connection between inflammation and fibrosis. Kidney Int Suppl. 2010 Dec; (119):S22-6. PMID: 21116313; PMCID: PMC4067095.
      Citations: 122     Fields:    Translation:HumansAnimalsCells
    149. Zeisberg EM, Kalluri R. Origins of cardiac fibroblasts. Circ Res. 2010 Nov 26; 107(11):1304-12. PMID: 21106947; PMCID: PMC3098499.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    150. Medici D, Shore EM, Lounev VY, Kaplan FS, Kalluri R, Olsen BR. Conversion of vascular endothelial cells into multipotent stem-like cells. Nat Med. 2010 Dec; 16(12):1400-6. PMID: 21102460; PMCID: PMC3209716.
      Citations: 352     Fields:    Translation:HumansAnimalsCells
    151. Krenning G, Zeisberg EM, Kalluri R. The origin of fibroblasts and mechanism of cardiac fibrosis. J Cell Physiol. 2010 Nov; 225(3):631-7. PMID: 20635395; PMCID: PMC3098503.
      Citations: 231     Fields:    Translation:HumansAnimalsCells
    152. Hertig A, Flier SN, Kalluri R. Contribution of epithelial plasticity to renal transplantation-associated fibrosis. Transplant Proc. 2010 Nov; 42(9 Suppl):S7-12. PMID: 21095454; PMCID: PMC4313550.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    153. LeBleu V, Sund M, Sugimoto H, Birrane G, Kanasaki K, Finan E, Miller CA, Gattone VH, McLaughlin H, Shield CF, Kalluri R. Identification of the NC1 domain of {alpha}3 chain as critical for {alpha}3{alpha}4{alpha}5 type IV collagen network assembly. J Biol Chem. 2010 Dec 31; 285(53):41874-85. PMID: 20847057; PMCID: PMC3009915.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    154. Force T, Bonow RO, Houser SR, Solaro RJ, Hershberger RE, Adhikari B, Anderson ME, Boineau R, Byrne BJ, Cappola TP, Kalluri R, LeWinter MM, Maron MS, Molkentin JD, Ommen SR, Regnier M, Tang WH, Tian R, Konstam MA, Maron BJ, Seidman CE. Research priorities in hypertrophic cardiomyopathy: report of a Working Group of the National Heart, Lung, and Blood Institute. Circulation. 2010 Sep 14; 122(11):1130-3. PMID: 20837938; PMCID: PMC3070356.
      Citations: 59     Fields:    Translation:Humans
    155. Wiig H, Keskin D, Kalluri R. Interaction between the extracellular matrix and lymphatics: consequences for lymphangiogenesis and lymphatic function. Matrix Biol. 2010 Oct; 29(8):645-56. PMID: 20727409; PMCID: PMC3992865.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    156. Nataraj D, Ernst A, Kalluri R. Idiopathic pulmonary fibrosis is associated with endothelial to mesenchymal transition. Am J Respir Cell Mol Biol. 2010 Aug; 43(2):129-30. PMID: 20651063.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    157. Wiig H, Tenstad O, Iversen PO, Kalluri R, Bjerkvig R. Interstitial fluid: the overlooked component of the tumor microenvironment? Fibrogenesis Tissue Repair. 2010 Jul 23; 3:12. PMID: 20653943; PMCID: PMC2920231.
      Citations: 44     
    158. Keskin D, Kalluri R. NF-kappaB-induced chromatin remodeling regulates angiogenesis. Blood. 2010 Jul 22; 116(3):312-3. PMID: 20651081.
      Citations: 2     Fields:    
    159. Hamano Y, Okude T, Shirai R, Sato I, Kimura R, Ogawa M, Ueda Y, Yokosuka O, Kalluri R, Ueda S. Lack of collagen XVIII/endostatin exacerbates immune-mediated glomerulonephritis. J Am Soc Nephrol. 2010 Sep; 21(9):1445-55. PMID: 20616167; PMCID: PMC3013523.
      Citations: 19     Fields:    Translation:AnimalsCells
    160. Polyak K, Kalluri R. The role of the microenvironment in mammary gland development and cancer. Cold Spring Harb Perspect Biol. 2010 Nov; 2(11):a003244. PMID: 20591988; PMCID: PMC2964182.
      Citations: 135     Fields:    Translation:HumansAnimalsCells
    161. Shenoy V, Kanasaki K, Kalluri R. Pre-eclampsia: connecting angiogenic and metabolic pathways. Trends Endocrinol Metab. 2010 Sep; 21(9):529-36. PMID: 20646932.
      Citations: 32     Fields:    Translation:Humans
    162. Bechtel W, McGoohan S, Zeisberg EM, Kalbacher H, Salant DJ, Kalluri R, Zeisberg M, M?ller GA, M?ller CA. Methylation determines fibroblast activation and fibrogenesis in the kidney. Nat Med. 2010 May; 16(5):544-50. PMID: 20418885; PMCID: PMC3106179.
      Citations: 261     Fields:    Translation:AnimalsCells
    163. Flier SN, Tanjore H, Kokkotou EG, Sugimoto H, Zeisberg M, Kalluri R. Identification of epithelial to mesenchymal transition as a novel source of fibroblasts in intestinal fibrosis. J Biol Chem. 2010 Jun 25; 285(26):20202-12. PMID: 20363741; PMCID: PMC2888433.
      Citations: 111     Fields:    Translation:HumansAnimalsCells
    164. Lee SB, Wong AP, Kanasaki K, Xu Y, Shenoy VK, McElrath TF, Whitesides GM, Kalluri R. Preeclampsia: 2-methoxyestradiol induces cytotrophoblast invasion and vascular development specifically under hypoxic conditions. Am J Pathol. 2010 Feb; 176(2):710-20. PMID: 20075204; PMCID: PMC2808078.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    165. LeBleu V, Sugimoto H, Mundel TM, Gerami-Naini B, Finan E, Miller CA, Gattone VH, Lu L, Shield CF, Folkman J, Kalluri R. Stem cell therapies benefit Alport syndrome. J Am Soc Nephrol. 2009 Nov; 20(11):2359-70. PMID: 19833902; PMCID: PMC2799182.
      Citations: 26     Fields:    Translation:AnimalsCells
    166. Kizu A, Medici D, Kalluri R. Endothelial-mesenchymal transition as a novel mechanism for generating myofibroblasts during diabetic nephropathy. Am J Pathol. 2009 Oct; 175(4):1371-3. PMID: 19729485; PMCID: PMC2751533.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    167. Ayala F, Dewar R, Kieran M, Kalluri R. Contribution of bone microenvironment to leukemogenesis and leukemia progression. Leukemia. 2009 Dec; 23(12):2233-41. PMID: 19727127; PMCID: PMC4313556.
      Citations: 106     Fields:    Translation:HumansCells
    168. Kanasaki K, Kalluri R. The biology of preeclampsia. Kidney Int. 2009 Oct; 76(8):831-7. PMID: 19657323; PMCID: PMC4313558.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    169. Duncan MB, Kalluri R. Parstatin, a novel protease-activated receptor 1-derived inhibitor of angiogenesis. Mol Interv. 2009 Aug; 9(4):168-70. PMID: 19720748; PMCID: PMC2863086.
      Citations: 2     Fields:    Translation:HumansAnimals
    170. Hertig A, Gangadhar T, Kalluri R. Renal studies provide an insight into cardiac extracellular matrix remodeling during health and disease. J Mol Cell Cardiol. 2010 Mar; 48(3):497-503. PMID: 19646990; PMCID: PMC4457469.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    171. Lee SB, Kanasaki K, Kalluri R. Circulating TGF-beta1 as a reliable biomarker for chronic kidney disease progression in the African-American population. Kidney Int. 2009 Jul; 76(1):10-2. PMID: 19528989; PMCID: PMC4313549.
      Citations: 6     Fields:    Translation:Humans
    172. Eikesdal HP, Kalluri R. Drug resistance associated with antiangiogenesis therapy. Semin Cancer Biol. 2009 Oct; 19(5):310-7. PMID: 19524042; PMCID: PMC4001703.
      Citations: 19     Fields:    Translation:Humans
    173. Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. J Clin Invest. 2009 Jun; 119(6):1420-8. PMID: 19487818; PMCID: PMC2689101.
      Citations: 4296     Fields:    Translation:HumansAnimalsCells
    174. Sund M, Kalluri R. Tumor stroma derived biomarkers in cancer. Cancer Metastasis Rev. 2009 Jun; 28(1-2):177-83. PMID: 19259624; PMCID: PMC4476244.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    175. Kalluri R. EMT: when epithelial cells decide to become mesenchymal-like cells. J Clin Invest. 2009 Jun; 119(6):1417-9. PMID: 19487817; PMCID: PMC2689122.
      Citations: 398     Fields:    Translation:HumansAnimalsCells
    176. Sohn RL, Huang P, Kawahara G, Mitchell M, Guyon J, Kalluri R, Kunkel LM, Gussoni E. A role for nephrin, a renal protein, in vertebrate skeletal muscle cell fusion. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9274-9. PMID: 19470472; PMCID: PMC2695070.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    177. Chang SH, Kanasaki K, Gocheva V, Blum G, Harper J, Moses MA, Shih SC, Nagy JA, Joyce J, Bogyo M, Kalluri R, Dvorak HF. VEGF-A induces angiogenesis by perturbing the cathepsin-cysteine protease inhibitor balance in venules, causing basement membrane degradation and mother vessel formation. Cancer Res. 2009 May 15; 69(10):4537-44. PMID: 19435903; PMCID: PMC2683911.
      Citations: 49     Fields:    Translation:Animals
    178. Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, Asara JM. Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis. Science. 2009 May 01; 324(5927):626-31. PMID: 19407199.
      Citations: 59     Fields:    Translation:AnimalsCells
    179. Zavadil J, Haley J, Kalluri R, Muthuswamy SK, Thompson E. Epithelial-mesenchymal transition. Cancer Res. 2008 Dec 01; 68(23):9574-7. PMID: 19047131.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    180. Zeisberg EM, Potenta SE, Sugimoto H, Zeisberg M, Kalluri R. Fibroblasts in kidney fibrosis emerge via endothelial-to-mesenchymal transition. J Am Soc Nephrol. 2008 Dec; 19(12):2282-7. PMID: 18987304; PMCID: PMC2588112.
      Citations: 387     Fields:    Translation:AnimalsCells
    181. Eikesdal HP, Sugimoto H, Birrane G, Maeshima Y, Cooke VG, Kieran M, Kalluri R. Identification of amino acids essential for the antiangiogenic activity of tumstatin and its use in combination antitumor activity. Proc Natl Acad Sci U S A. 2008 Sep 30; 105(39):15040-5. PMID: 18818312; PMCID: PMC2567489.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    182. Potenta S, Zeisberg E, Kalluri R. The role of endothelial-to-mesenchymal transition in cancer progression. Br J Cancer. 2008 Nov 04; 99(9):1375-9. PMID: 18797460; PMCID: PMC2579683.
      Citations: 246     Fields:    Translation:HumansAnimalsCells
    183. Nyberg P, Xie L, Sugimoto H, Colorado P, Sund M, Holthaus K, Sudhakar A, Salo T, Kalluri R. Characterization of the anti-angiogenic properties of arresten, an alpha1beta1 integrin-dependent collagen-derived tumor suppressor. Exp Cell Res. 2008 Nov 01; 314(18):3292-305. PMID: 18775695; PMCID: PMC2613512.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    184. LeBleu VS, Kalluri R. Stem cell-based therapy for glomerular diseases: an evolving concept. J Am Soc Nephrol. 2008 Sep; 19(9):1621-3. PMID: 18701605.
      Citations: 4     Fields:    Translation:Animals
    185. Kalluri R, Han Y. Targeting TGF-beta and the extracellular matrix in Marfan's syndrome. Dev Cell. 2008 Jul; 15(1):1-2. PMID: 18606132.
      Citations: 8     Fields:    Translation:HumansCells
    186. Kanasaki K, Palmsten K, Sugimoto H, Ahmad S, Hamano Y, Xie L, Parry S, Augustin HG, Gattone VH, Folkman J, Strauss JF, Kalluri R. Deficiency in catechol-O-methyltransferase and 2-methoxyoestradiol is associated with pre-eclampsia. Nature. 2008 Jun 19; 453(7198):1117-21. PMID: 18469803.
      Citations: 138     Fields:    Translation:HumansAnimalsCells
    187. Zeisberg M, Kalluri R. Fibroblasts emerge via epithelial-mesenchymal transition in chronic kidney fibrosis. Front Biosci. 2008 May 01; 13:6991-8. PMID: 18508710.
      Citations: 55     Fields:    Translation:HumansCells
    188. Nyberg P, Salo T, Kalluri R. Tumor microenvironment and angiogenesis. Front Biosci. 2008 May 01; 13:6537-53. PMID: 18508679.
      Citations: 71     Fields:    Translation:HumansCells
    189. Zeisberg M, Kalluri R. Reversal of experimental renal fibrosis by BMP7 provides insights into novel therapeutic strategies for chronic kidney disease. Pediatr Nephrol. 2008 Sep; 23(9):1395-8. PMID: 18446379.
      Citations: 33     Fields:    Translation:HumansAnimals
    190. Mundel TM, Yliniemi AM, Maeshima Y, Sugimoto H, Kieran M, Kalluri R. Type IV collagen alpha6 chain-derived noncollagenous domain 1 (alpha6(IV)NC1) inhibits angiogenesis and tumor growth. Int J Cancer. 2008 Apr 15; 122(8):1738-44. PMID: 18074349.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    191. Kalluri R, Kanasaki K. RNA interference: generic block on angiogenesis. Nature. 2008 Apr 03; 452(7187):543-5. PMID: 18385725.
      Citations: 3     Fields:    Translation:HumansAnimals
    192. Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R. Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth. Exp Biol Med (Maywood). 2008 Feb; 233(2):155-62. PMID: 18222970.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    193. Lebleu VS, Sugimoto H, Miller CA, Gattone VH, Kalluri R. Lymphocytes are dispensable for glomerulonephritis but required for renal interstitial fibrosis in matrix defect-induced Alport renal disease. Lab Invest. 2008 Mar; 88(3):284-92. PMID: 18180701.
      Citations: 20     Fields:    Translation:AnimalsCells
    194. Tanjore H, Zeisberg EM, Gerami-Naini B, Kalluri R. Beta1 integrin expression on endothelial cells is required for angiogenesis but not for vasculogenesis. Dev Dyn. 2008 Jan; 237(1):75-82. PMID: 18058911.
      Citations: 47     Fields:    Translation:AnimalsCells
    195. Cooke VG, Kalluri R. Chapter 1. Molecular mechanism of type IV collagen-derived endogenous inhibitors of angiogenesis. Methods Enzymol. 2008; 444:1-19. PMID: 19007658.
      Citations: 7     Fields:    Translation:HumansAnimals
    196. Wei C, Altintas MM, Li J, Schwarz K, Zacchigna S, Xie L, Henger A, Schmid H, Rastaldi MP, Cowan P, Kretzler M, Parrilla R, Gupta V, Nikolic B, Kalluri R, Carmeliet P, Mundel P, Reiser J, M?ller CC, Bendayan M. Modification of kidney barrier function by the urokinase receptor. Nat Med. 2008 Jan; 14(1):55-63. PMID: 18084301.
      Citations: 268     Fields:    Translation:HumansAnimalsCells
    197. Kanasaki K, Kanda Y, Palmsten K, Tanjore H, Lee SB, Lebleu VS, Gattone VH, Kalluri R. Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus. Dev Biol. 2008 Jan 15; 313(2):584-93. PMID: 18082680; PMCID: PMC3947521.
      Citations: 73     Fields:    Translation:AnimalsCells
    198. Zeisberg EM, Potenta S, Xie L, Zeisberg M, Kalluri R. Discovery of endothelial to mesenchymal transition as a source for carcinoma-associated fibroblasts. Cancer Res. 2007 Nov 01; 67(21):10123-8. PMID: 17974953.
      Citations: 415     Fields:    Translation:AnimalsCells
    199. LeBleu VS, Macdonald B, Kalluri R. Structure and function of basement membranes. Exp Biol Med (Maywood). 2007 Oct; 232(9):1121-9. PMID: 17895520.
      Citations: 171     Fields:    Translation:HumansAnimals
    200. Zeisberg EM, Tarnavski O, Zeisberg M, Dorfman AL, McMullen JR, Gustafsson E, Chandraker A, Yuan X, Pu WT, Roberts AB, Neilson EG, Sayegh MH, Izumo S, Kalluri R. Endothelial-to-mesenchymal transition contributes to cardiac fibrosis. Nat Med. 2007 Aug; 13(8):952-61. PMID: 17660828.
      Citations: 939     Fields:    Translation:HumansAnimalsCells
    201. Tse JC, Kalluri R. Mechanisms of metastasis: epithelial-to-mesenchymal transition and contribution of tumor microenvironment. J Cell Biochem. 2007 Jul 01; 101(4):816-29. PMID: 17243120.
      Citations: 159     Fields:    Translation:HumansAnimalsCells
    202. Zeisberg M, Yang C, Martino M, Duncan MB, Rieder F, Tanjore H, Kalluri R. Fibroblasts derive from hepatocytes in liver fibrosis via epithelial to mesenchymal transition. J Biol Chem. 2007 Aug 10; 282(32):23337-47. PMID: 17562716.
      Citations: 315     Fields:    Translation:HumansAnimalsCells
    203. Mundel TM, Kalluri R. Type IV collagen-derived angiogenesis inhibitors. Microvasc Res. 2007 Sep-Nov; 74(2-3):85-9. PMID: 17602710; PMCID: PMC3998721.
      Citations: 79     Fields:    Translation:HumansAnimals
    204. Sugimoto H, Grahovac G, Zeisberg M, Kalluri R. Renal fibrosis and glomerulosclerosis in a new mouse model of diabetic nephropathy and its regression by bone morphogenic protein-7 and advanced glycation end product inhibitors. Diabetes. 2007 Jul; 56(7):1825-33. PMID: 17456853.
      Citations: 96     Fields:    Translation:HumansAnimals
    205. Cosgrove D, Kalluri R, Miner JH, Segal Y, Borza DB. Choosing a mouse model to study the molecular pathobiology of Alport glomerulonephritis. Kidney Int. 2007 Apr; 71(7):615-8. PMID: 17290292.
      Citations: 24     Fields:    Translation:Animals
    206. Teng Y, Zeisberg M, Kalluri R. Transcriptional regulation of epithelial-mesenchymal transition. J Clin Invest. 2007 Feb; 117(2):304-6. PMID: 17273552; PMCID: PMC1783811.
      Citations: 18     Fields:    Translation:AnimalsCells
    207. Garovic VD, Wagner SJ, Petrovic LM, Gray CE, Hall P, Sugimoto H, Kalluri R, Grande JP. Glomerular expression of nephrin and synaptopodin, but not podocin, is decreased in kidney sections from women with preeclampsia. Nephrol Dial Transplant. 2007 Apr; 22(4):1136-43. PMID: 17255128.
      Citations: 49     Fields:    Translation:HumansAnimals
    208. Hahm K, Lukashev ME, Luo Y, Yang WJ, Dolinski BM, Weinreb PH, Simon KJ, Chun Wang L, Leone DR, Lobb RR, McCrann DJ, Allaire NE, Horan GS, Fogo A, Kalluri R, Shield CF, Sheppard D, Gardner HA, Violette SM. Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse. Am J Pathol. 2007 Jan; 170(1):110-25. PMID: 17200187; PMCID: PMC1762706.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    209. Sugimoto H, Mundel TM, Kieran MW, Kalluri R. Identification of fibroblast heterogeneity in the tumor microenvironment. Cancer Biol Ther. 2006 Dec; 5(12):1640-6. PMID: 17106243.
      Citations: 317     Fields:    Translation:HumansAnimalsCells
    210. Sugimoto H, Yang C, LeBleu VS, Soubasakos MA, Giraldo M, Zeisberg M, Kalluri R. BMP-7 functions as a novel hormone to facilitate liver regeneration. FASEB J. 2007 Jan; 21(1):256-64. PMID: 17116741.
      Citations: 37     Fields:    Translation:HumansAnimals
    211. Dandapani SV, Sugimoto H, Matthews BD, Kolb RJ, Sinha S, Gerszten RE, Zhou J, Ingber DE, Kalluri R, Pollak MR. Alpha-actinin-4 is required for normal podocyte adhesion. J Biol Chem. 2007 Jan 05; 282(1):467-77. PMID: 17082197.
      Citations: 59     Fields:    Translation:AnimalsCells
    212. Kalluri R, Zeisberg E. Controlling angiogenesis in heart valves. Nat Med. 2006 Oct; 12(10):1118-9. PMID: 17024200.
      Citations: 5     Fields:    Translation:HumansAnimals
    213. Kalluri R. Proteinuria with and without renal glomerular podocyte effacement. J Am Soc Nephrol. 2006 Sep; 17(9):2383-9. PMID: 16914535.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    214. Farazi PA, Zeisberg M, Glickman J, Zhang Y, Kalluri R, DePinho RA. Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice. Cancer Res. 2006 Jul 01; 66(13):6622-7. PMID: 16818635.
      Citations: 43     Fields:    Translation:AnimalsCells
    215. Kalluri R, Zeisberg M. Fibroblasts in cancer. Nat Rev Cancer. 2006 May; 6(5):392-401. PMID: 16572188.
      Citations: 1920     Fields:    Translation:HumansAnimalsCells
    216. Sugimoto H, Mundel TM, Sund M, Xie L, Cosgrove D, Kalluri R. Bone-marrow-derived stem cells repair basement membrane collagen defects and reverse genetic kidney disease. Proc Natl Acad Sci U S A. 2006 May 09; 103(19):7321-6. PMID: 16648256; PMCID: PMC1464339.
      Citations: 72     Fields:    Translation:AnimalsCells
    217. Lee JM, Dedhar S, Kalluri R, Thompson EW. The epithelial-mesenchymal transition: new insights in signaling, development, and disease. J Cell Biol. 2006 Mar 27; 172(7):973-81. PMID: 16567498; PMCID: PMC2063755.
      Citations: 882     Fields:    Translation:HumansAnimalsCells
    218. Zeisberg M, Khurana M, Rao VH, Cosgrove D, Rougier JP, Werner MC, Shield CF, Werb Z, Kalluri R. Stage-specific action of matrix metalloproteinases influences progressive hereditary kidney disease. PLoS Med. 2006 Apr; 3(4):e100. PMID: 16509766; PMCID: PMC1391977.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    219. Tanjore H, Kalluri R. The role of type IV collagen and basement membranes in cancer progression and metastasis. Am J Pathol. 2006 Mar; 168(3):715-7. PMID: 16507886; PMCID: PMC1606530.
      Citations: 45     Fields:    Translation:HumansCells
    220. Zeisberg M, Kramer K, Sindhi N, Sarkar P, Upton M, Kalluri R. De-differentiation of primary human hepatocytes depends on the composition of specialized liver basement membrane. Mol Cell Biochem. 2006 Feb; 283(1-2):181-9. PMID: 16444601.
      Citations: 27     Fields:    Translation:HumansCells
    221. Wang B, Sun J, Kitamoto S, Yang M, Grubb A, Chapman HA, Kalluri R, Shi GP. Cathepsin S controls angiogenesis and tumor growth via matrix-derived angiogenic factors. J Biol Chem. 2006 Mar 03; 281(9):6020-9. PMID: 16365041.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    222. Sund M, Zeisberg M, Kalluri R. Endogenous stimulators and inhibitors of angiogenesis in gastrointestinal cancers: basic science to clinical application. Gastroenterology. 2005 Dec; 129(6):2076-91. PMID: 16344073.
      Citations: 8     Fields:    Translation:HumansCells
    223. Zehnder AF, Adams JC, Santi PA, Kristiansen AG, Wacharasindhu C, Mann S, Kalluri R, Gregory MC, Kashtan CE, Merchant SN. Distribution of type IV collagen in the cochlea in Alport syndrome. Arch Otolaryngol Head Neck Surg. 2005 Nov; 131(11):1007-13. PMID: 16301374.
      Citations: 20     Fields:    Translation:HumansCells
    224. MacDonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, Kalluri R. Zebrafish to humans: evolution of the alpha3-chain of type IV collagen and emergence of the autoimmune epitopes associated with Goodpasture syndrome. Blood. 2006 Mar 01; 107(5):1908-15. PMID: 16254142; PMCID: PMC1895704.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    225. Sudhakar A, Nyberg P, Keshamouni VG, Mannam AP, Li J, Sugimoto H, Cosgrove D, Kalluri R. Human alpha1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by alpha1beta1 integrin. J Clin Invest. 2005 Oct; 115(10):2801-10. PMID: 16151532; PMCID: PMC1199529.
      Citations: 67     Fields:    Translation:HumansCells
    226. Okada H, Kalluri R. Cellular and molecular pathways that lead to progression and regression of renal fibrogenesis. Curr Mol Med. 2005 Aug; 5(5):467-74. PMID: 16101477.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    227. Hamano Y, Kalluri R. Tumstatin, the NC1 domain of alpha3 chain of type IV collagen, is an endogenous inhibitor of pathological angiogenesis and suppresses tumor growth. Biochem Biophys Res Commun. 2005 Jul 29; 333(2):292-8. PMID: 15979458.
      Citations: 36     Fields:    Translation:HumansAnimals
    228. Okada H, Kalluri R. Recapitulation of kidney development paradigms by BMP-7 reverses chronic renal injury. Clin Exp Nephrol. 2005 Jun; 9(2):100-1. PMID: 15980942.
      Citations: 3     Fields:    Translation:HumansAnimals
    229. Reiser J, Polu KR, Kenlan P, Altintas MM, Wei C, Faul C, Herbert S, Villegas I, Avila-Casado C, McGee M, Sugimoto H, Brown D, Kalluri R, Mundel P, Smith PL, Clapham DE, Pollak MR, M?ller CC. TRPC6 is a glomerular slit diaphragm-associated channel required for normal renal function. Nat Genet. 2005 Jul; 37(7):739-44. PMID: 15924139; PMCID: PMC1360984.
      Citations: 349     Fields:    Translation:HumansCells
    230. Nyberg P, Xie L, Kalluri R. Endogenous inhibitors of angiogenesis. Cancer Res. 2005 May 15; 65(10):3967-79. PMID: 15899784.
      Citations: 177     Fields:    Translation:HumansAnimals
    231. Sund M, Maeshima Y, Kalluri R. Bifunctional promoter of type IV collagen COL4A5 and COL4A6 genes regulates the expression of alpha5 and alpha6 chains in a distinct cell-specific fashion. Biochem J. 2005 May 01; 387(Pt 3):755-61. PMID: 15598179; PMCID: PMC1135006.
      Citations: 5     Fields:    Translation:AnimalsCells
    232. Reynolds J, Prodromidi EI, Juggapah JK, Abbott DS, Holthaus KA, Kalluri R, Pusey CD. Nasal administration of recombinant rat alpha3(IV)NC1 prevents the development of experimental autoimmune glomerulonephritis in the WKY rat. J Am Soc Nephrol. 2005 May; 16(5):1350-9. PMID: 15814836.
      Citations: 15     Fields:    Translation:Animals
    233. Charytan D, MacDonald B, Sugimoto H, Pastan S, Staton G, Hennigar R, Kalluri R. An unusual case of pulmonary-renal syndrome associated with defects in type IV collagen composition and anti-glomerular basement membrane autoantibodies. Am J Kidney Dis. 2005 Apr; 45(4):743-8. PMID: 15806477.
      Citations: 2     Fields:    Translation:HumansCells
    234. Sund M, Hamano Y, Sugimoto H, Sudhakar A, Soubasakos M, Yerramalla U, Benjamin LE, Lawler J, Kieran M, Shah A, Kalluri R. Function of endogenous inhibitors of angiogenesis as endothelium-specific tumor suppressors. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2934-9. PMID: 15710885; PMCID: PMC549486.
      Citations: 54     Fields:    Translation:AnimalsCells
    235. Krishna TH, Mahipal S, Sudhakar A, Sugimoto H, Kalluri R, Rao KS. Reduced DNA gap repair in aging rat neuronal extracts and its restoration by DNA polymerase beta and DNA-ligase. J Neurochem. 2005 Feb; 92(4):818-23. PMID: 15686483.
      Citations: 19     Fields:    Translation:AnimalsCells
    236. Zeisberg M, Soubasakos MA, Kalluri R. Animal models of renal fibrosis. Methods Mol Med. 2005; 117:261-72. PMID: 16118458.
      Citations: 12     Fields:    Translation:Animals
    237. Grant MA, Kalluri R. Structural basis for the functions of endogenous angiogenesis inhibitors. Cold Spring Harb Symp Quant Biol. 2005; 70:399-410. PMID: 16869777.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    238. Zeisberg M, Shah AA, Kalluri R. Bone morphogenic protein-7 induces mesenchymal to epithelial transition in adult renal fibroblasts and facilitates regeneration of injured kidney. J Biol Chem. 2005 Mar 04; 280(9):8094-100. PMID: 15591043.
      Citations: 99     Fields:    Translation:HumansAnimalsCells
    239. Zeisberg M, Kalluri R. Experimental strategies to reverse chronic renal disease. Blood Purif. 2004; 22(5):440-5. PMID: 15359103.
      Citations: 6     Fields:    Translation:Humans
    240. Sund M, Xie L, Kalluri R. The contribution of vascular basement membranes and extracellular matrix to the mechanics of tumor angiogenesis. APMIS. 2004 Jul-Aug; 112(7-8):450-62. PMID: 15563309.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    241. Benigni A, Gagliardini E, Tomasoni S, Abbate M, Ruggenenti P, Kalluri R, Remuzzi G. Selective impairment of gene expression and assembly of nephrin in human diabetic nephropathy. Kidney Int. 2004 Jun; 65(6):2193-200. PMID: 15149332.
      Citations: 41     Fields:    Translation:Humans
    242. Charytan D, Torre A, Khurana M, Nicastri A, Stillman IE, Kalluri R. Allograft rejection and glomerular basement membrane antibodies in Alport's syndrome. J Nephrol. 2004 May-Jun; 17(3):431-5. PMID: 15365966.
      Citations: 1     Fields:    Translation:Humans
    243. Reiser J, von Gersdorff G, Loos M, Oh J, Asanuma K, Giardino L, Rastaldi MP, Calvaresi N, Watanabe H, Schwarz K, Faul C, Kretzler M, Davidson A, Sugimoto H, Kalluri R, Sharpe AH, Kreidberg JA, Mundel P. Induction of B7-1 in podocytes is associated with nephrotic syndrome. J Clin Invest. 2004 May; 113(10):1390-7. PMID: 15146236; PMCID: PMC406528.
      Citations: 267     Fields:    Translation:HumansAnimalsCells
    244. Zeisberg M, Kalluri R, M?ller GA. Are there endogenous molecules that protect kidneys from injury? The case for bone morphogenic protein-7 (BMP-7). Nephrol Dial Transplant. 2004 Apr; 19(4):759-61. PMID: 15031324.
      Citations: 7     Fields:    Translation:Animals
    245. Hamano Y, Sugimoto H, Soubasakos MA, Kieran M, Olsen BR, Lawler J, Sudhakar A, Kalluri R. Thrombospondin-1 associated with tumor microenvironment contributes to low-dose cyclophosphamide-mediated endothelial cell apoptosis and tumor growth suppression. Cancer Res. 2004 Mar 01; 64(5):1570-4. PMID: 14996710.
      Citations: 53     Fields:    Translation:AnimalsCells
    246. Folkman J, Kalluri R. Cancer without disease. Nature. 2004 Feb 26; 427(6977):787. PMID: 14985739.
      Citations: 164     Fields:    Translation:Humans
    247. Zeisberg M, Kalluri R. The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med (Berl). 2004 Mar; 82(3):175-81. PMID: 14752606.
      Citations: 166     Fields:    Translation:HumansAnimalsCells
    248. Bhattacharya G, Kalluri R, Orten DJ, Kimberling WJ, Cosgrove D. A domain-specific usherin/collagen IV interaction may be required for stable integration into the basement membrane superstructure. J Cell Sci. 2004 Jan 15; 117(Pt 2):233-42. PMID: 14676276.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    249. Yang C, Zeisberg M, Lively JC, Nyberg P, Afdhal N, Kalluri R. Integrin alpha1beta1 and alpha2beta1 are the key regulators of hepatocarcinoma cell invasion across the fibrotic matrix microenvironment. Cancer Res. 2003 Dec 01; 63(23):8312-7. PMID: 14678990.
      Citations: 55     Fields:    Translation:HumansCells
    250. Kalluri R, Neilson EG. Epithelial-mesenchymal transition and its implications for fibrosis. J Clin Invest. 2003 Dec; 112(12):1776-84. PMID: 14679171; PMCID: PMC297008.
      Citations: 1109     Fields:    Translation:HumansAnimalsCells
    251. Salama AD, Chaudhry AN, Holthaus KA, Mosley K, Kalluri R, Sayegh MH, Lechler RI, Pusey CD, Lightstone L. Regulation by CD25+ lymphocytes of autoantigen-specific T-cell responses in Goodpasture's (anti-GBM) disease. Kidney Int. 2003 Nov; 64(5):1685-94. PMID: 14531801.
      Citations: 33     Fields:    Translation:HumansCells
    252. Charytan DM, Le DD, Grossman JM, Holthaus KA, Kalluri R. Antiglomerular basement membrane autoantibodies are nonpathogenic in Wegener's granulomatosis. Am J Med. 2003 Oct 01; 115(5):414-5. PMID: 14553885.
      Citations: 1     Fields:    Translation:Humans
    253. Zeisberg M, Bottiglio C, Kumar N, Maeshima Y, Strutz F, Kalluri R, M?ller GA. Bone morphogenic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am J Physiol Renal Physiol. 2003 Dec; 285(6):F1060-7. PMID: 12915382.
      Citations: 116     Fields:    Translation:HumansAnimalsCells
    254. Gagliardini E, Benigni A, Tomasoni S, Abbate M, Kalluri R, Remuzzi G. Targeted downregulation of extracellular nephrin in human IgA nephropathy. Am J Nephrol. 2003 Jul-Aug; 23(4):277-86. PMID: 12853730.
      Citations: 12     Fields:    Translation:HumansCells
    255. Zeisberg M, Hanai J, Sugimoto H, Mammoto T, Charytan D, Strutz F, Kalluri R. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med. 2003 Jul; 9(7):964-8. PMID: 12808448.
      Citations: 557     Fields:    Translation:AnimalsCells
    256. McDonald GA, Sarkar P, Rennke H, Unemori E, Kalluri R, Sukhatme VP. Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo. Am J Physiol Renal Physiol. 2003 Jul; 285(1):F59-67. PMID: 12820641.
      Citations: 21     Fields:    Translation:AnimalsCells
    257. Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer. 2003 Jun; 3(6):422-33. PMID: 12778132.
      Citations: 613     Fields:    Translation:Cells
    258. Kos CH, Le TC, Sinha S, Henderson JM, Kim SH, Sugimoto H, Kalluri R, Gerszten RE, Pollak MR. Mice deficient in alpha-actinin-4 have severe glomerular disease. J Clin Invest. 2003 Jun; 111(11):1683-90. PMID: 12782671; PMCID: PMC156110.
      Citations: 89     Fields:    Translation:AnimalsCells
    259. Hamano Y, Zeisberg M, Sugimoto H, Lively JC, Maeshima Y, Yang C, Hynes RO, Werb Z, Sudhakar A, Kalluri R. Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. Cancer Cell. 2003 Jun; 3(6):589-601. PMID: 12842087; PMCID: PMC2775452.
      Citations: 195     Fields:    Translation:HumansAnimalsCells
    260. Hopfer H, Maron R, Butzmann U, Helmchen U, Weiner HL, Kalluri R. The importance of cell-mediated immunity in the course and severity of autoimmune anti-glomerular basement membrane disease in mice. FASEB J. 2003 May; 17(8):860-8. PMID: 12724345.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    261. Sudhakar A, Sugimoto H, Yang C, Lively J, Zeisberg M, Kalluri R. Human tumstatin and human endostatin exhibit distinct antiangiogenic activities mediated by alpha v beta 3 and alpha 5 beta 1 integrins. Proc Natl Acad Sci U S A. 2003 Apr 15; 100(8):4766-71. PMID: 12682293; PMCID: PMC153630.
      Citations: 155     Fields:    Translation:HumansCells
    262. Sugimoto H, Hamano Y, Charytan D, Cosgrove D, Kieran M, Sudhakar A, Kalluri R. Neutralization of circulating vascular endothelial growth factor (VEGF) by anti-VEGF antibodies and soluble VEGF receptor 1 (sFlt-1) induces proteinuria. J Biol Chem. 2003 Apr 11; 278(15):12605-8. PMID: 12538598.
      Citations: 160     Fields:    Translation:Animals
    263. Yang C, Zeisberg M, Mosterman B, Sudhakar A, Yerramalla U, Holthaus K, Xu L, Eng F, Afdhal N, Kalluri R. Liver fibrosis: insights into migration of hepatic stellate cells in response to extracellular matrix and growth factors. Gastroenterology. 2003 Jan; 124(1):147-59. PMID: 12512039.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    264. Kalluri R, Zeisberg M. Exploring the connection between chronic renal fibrosis and bone morphogenic protein-7. Histol Histopathol. 2003 01; 18(1):217-24. PMID: 12507301.
      Citations: 5     Fields:    Translation:HumansAnimals
    265. Tsukaguchi H, Sudhakar A, Le TC, Nguyen T, Yao J, Schwimmer JA, Schachter AD, Poch E, Abreu PF, Appel GB, Pereira AB, Kalluri R, Pollak MR. NPHS2 mutations in late-onset focal segmental glomerulosclerosis: R229Q is a common disease-associated allele. J Clin Invest. 2002 Dec; 110(11):1659-66. PMID: 12464671; PMCID: PMC151634.
      Citations: 88     Fields:    Translation:HumansCells
    266. Iglesias-de la Cruz MC, Ziyadeh FN, Isono M, Kouahou M, Han DC, Kalluri R, Mundel P, Chen S. Effects of high glucose and TGF-beta1 on the expression of collagen IV and vascular endothelial growth factor in mouse podocytes. Kidney Int. 2002 Sep; 62(3):901-13. PMID: 12164872.
      Citations: 62     Fields:    Translation:AnimalsCells
    267. Natoli TA, Liu J, Eremina V, Hodgens K, Li C, Hamano Y, Mundel P, Kalluri R, Miner JH, Quaggin SE, Kreidberg JA. A mutant form of the Wilms' tumor suppressor gene WT1 observed in Denys-Drash syndrome interferes with glomerular capillary development. J Am Soc Nephrol. 2002 Aug; 13(8):2058-67. PMID: 12138137.
      Citations: 12     Fields:    Translation:AnimalsCells
    268. Bloom RD, O'Connor T, Cizman B, Kalluri R, Naji A, Madaio MP. Intrathymic kidney cells delay the onset of lupus nephritis in MRL-lpr/lpr mice. Int Immunol. 2002 Aug; 14(8):867-71. PMID: 12147623.
      Citations: 4     Fields:    Translation:AnimalsCells
    269. Zeisberg M, Ericksen MB, Hamano Y, Neilson EG, Ziyadeh F, Kalluri R. Differential expression of type IV collagen isoforms in rat glomerular endothelial and mesangial cells. Biochem Biophys Res Commun. 2002 Jul 12; 295(2):401-7. PMID: 12150963.
      Citations: 10     Fields:    Translation:AnimalsCells
    270. Hamano Y, Grunkemeyer JA, Sudhakar A, Zeisberg M, Cosgrove D, Morello R, Lee B, Sugimoto H, Kalluri R. Determinants of vascular permeability in the kidney glomerulus. J Biol Chem. 2002 Aug 23; 277(34):31154-62. PMID: 12039968.
      Citations: 47     Fields:    Translation:AnimalsCells
    271. Meyers KE, Allen J, Gehret J, Jacobovits A, Gallo M, Neilson EG, Hopfer H, Kalluri R, Madaio MP. Human antiglomerular basement membrane autoantibody disease in XenoMouse II. Kidney Int. 2002 May; 61(5):1666-73. PMID: 11967016.
      Citations: 8     Fields:    Translation:HumansAnimals
    272. Reimer CL, Agata N, Tammam JG, Bamberg M, Dickerson WM, Kamphaus GD, Rook SL, Milhollen M, Fram R, Kalluri R, Kufe D, Kharbanda S. Antineoplastic effects of chemotherapeutic agents are potentiated by NM-3, an inhibitor of angiogenesis. Cancer Res. 2002 Feb 01; 62(3):789-95. PMID: 11830534.
      Citations: 10     Fields:    Translation:HumansAnimals
    273. Maeshima Y, Sudhakar A, Lively JC, Ueki K, Kharbanda S, Kahn CR, Sonenberg N, Hynes RO, Kalluri R. Tumstatin, an endothelial cell-specific inhibitor of protein synthesis. Science. 2002 Jan 04; 295(5552):140-3. PMID: 11778052.
      Citations: 109     Fields:    Translation:HumansAnimalsCells
    274. Kalluri R. Discovery of type IV collagen non-collagenous domains as novel integrin ligands and endogenous inhibitors of angiogenesis. Cold Spring Harb Symp Quant Biol. 2002; 67:255-66. PMID: 12858548.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    275. Zeisberg M, Bonner G, Maeshima Y, Colorado P, Strutz F, Kalluri R, M?ller GA. Renal fibrosis: collagen composition and assembly regulates epithelial-mesenchymal transdifferentiation. Am J Pathol. 2001 Oct; 159(4):1313-21. PMID: 11583959; PMCID: PMC1850511.
      Citations: 113     Fields:    Translation:HumansAnimalsCells
    276. Okada H, Inoue T, Kanno Y, Kobayashi T, Ban S, Kalluri R, Suzuki H. Renal fibroblast-like cells in Goodpasture syndrome rats. Kidney Int. 2001 Aug; 60(2):597-606. PMID: 11473642.
      Citations: 3     Fields:    Translation:AnimalsCells
    277. Maeshima Y, Yerramalla UL, Dhanabal M, Holthaus KA, Barbashov S, Kharbanda S, Reimer C, Manfredi M, Dickerson WM, Kalluri R. Extracellular matrix-derived peptide binds to alpha(v)beta(3) integrin and inhibits angiogenesis. J Biol Chem. 2001 Aug 24; 276(34):31959-68. PMID: 11399763.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    278. Benigni A, Tomasoni S, Gagliardini E, Zoja C, Grunkemeyer JA, Kalluri R, Remuzzi G. Blocking angiotensin II synthesis/activity preserves glomerular nephrin in rats with severe nephrosis. J Am Soc Nephrol. 2001 May; 12(5):941-948. PMID: 11316852.
      Citations: 35     Fields:    Translation:AnimalsCells
    279. Karumanchi SA, Jha V, Ramchandran R, Karihaloo A, Tsiokas L, Chan B, Dhanabal M, Hanai JI, Venkataraman G, Shriver Z, Keiser N, Kalluri R, Zeng H, Mukhopadhyay D, Chen RL, Lander AD, Hagihara K, Yamaguchi Y, Sasisekharan R, Cantley L, Sukhatme VP. Cell surface glypicans are low-affinity endostatin receptors. Mol Cell. 2001 Apr; 7(4):811-22. PMID: 11336704.
      Citations: 65     Fields:    Translation:AnimalsCells
    280. Maeshima Y, Manfredi M, Reimer C, Holthaus KA, Hopfer H, Chandamuri BR, Kharbanda S, Kalluri R. Identification of the anti-angiogenic site within vascular basement membrane-derived tumstatin. J Biol Chem. 2001 May 04; 276(18):15240-8. PMID: 11278365.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    281. Chugh S, Yuan H, Topham PS, Haydar SA, Mittal V, Taylor GA, Kalluri R, Salant DJ. Aminopeptidase A: a nephritogenic target antigen of nephrotoxic serum. Kidney Int. 2001 Feb; 59(2):601-13. PMID: 11168941.
      Citations: 25     Fields:    Translation:AnimalsCells
    282. Salloum RM, Jaskowiak NT, Mauceri HJ, Seetharam S, Beckett MA, Koons AM, Hari DM, Gupta VK, Reimer C, Kalluri R, Posner MC, Hellman S, Kufe DW, Weichselbaum RR. NM-3, an isocoumarin, increases the antitumor effects of radiotherapy without toxicity. Cancer Res. 2000 Dec 15; 60(24):6958-63. PMID: 11156396.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    283. Cosgrove D, Rodgers K, Meehan D, Miller C, Bovard K, Gilroy A, Gardner H, Kotelianski V, Gotwals P, Amatucci A, Kalluri R. Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy. Am J Pathol. 2000 Nov; 157(5):1649-59. PMID: 11073824; PMCID: PMC1885718.
      Citations: 68     Fields:    Translation:Animals
    284. Hanna NN, Seetharam S, Mauceri HJ, Beckett MA, Jaskowiak NT, Salloum RM, Hari D, Dhanabal M, Ramchandran R, Kalluri R, Sukhatme VP, Kufe DW, Weichselbaum RR. Antitumor interaction of short-course endostatin and ionizing radiation. Cancer J. 2000 Sep-Oct; 6(5):287-93. PMID: 11079167.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    285. Maeshima Y, Colorado PC, Kalluri R. Two RGD-independent alpha vbeta 3 integrin binding sites on tumstatin regulate distinct anti-tumor properties. J Biol Chem. 2000 Aug 04; 275(31):23745-50. PMID: 10837460.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    286. Maeshima Y, Colorado PC, Torre A, Holthaus KA, Grunkemeyer JA, Ericksen MB, Hopfer H, Xiao Y, Stillman IE, Kalluri R. Distinct antitumor properties of a type IV collagen domain derived from basement membrane. J Biol Chem. 2000 Jul 14; 275(28):21340-8. PMID: 10766752.
      Citations: 101     Fields:    Translation:HumansAnimalsCells
    287. Rutgers A, Meyers KE, Canziani G, Kalluri R, Lin J, Madaio MP. High affinity of anti-GBM antibodies from Goodpasture and transplanted Alport patients to alpha3(IV)NC1 collagen. Kidney Int. 2000 Jul; 58(1):115-22. PMID: 10886555.
      Citations: 12     Fields:    Translation:HumansAnimals
    288. Kalluri R, Sukhatme VP. Fibrosis and angiogenesis. Curr Opin Nephrol Hypertens. 2000 Jul; 9(4):413-8. PMID: 10926178.
      Citations: 28     Fields:    Translation:HumansAnimals
    289. Kalluri R, Cantley LG, Kerjaschki D, Neilson EG. Reactive oxygen species expose cryptic epitopes associated with autoimmune goodpasture syndrome. J Biol Chem. 2000 Jun 30; 275(26):20027-32. PMID: 10748075.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    290. Colorado PC, Torre A, Kamphaus G, Maeshima Y, Hopfer H, Takahashi K, Volk R, Zamborsky ED, Herman S, Sarkar PK, Ericksen MB, Dhanabal M, Simons M, Post M, Kufe DW, Weichselbaum RR, Sukhatme VP, Kalluri R. Anti-angiogenic cues from vascular basement membrane collagen. Cancer Res. 2000 May 01; 60(9):2520-6. PMID: 10811134.
      Citations: 131     Fields:    Translation:HumansAnimalsCells
    291. Kalluri R, Cosgrove D. Assembly of type IV collagen. Insights from alpha3(IV) collagen-deficient mice. J Biol Chem. 2000 Apr 28; 275(17):12719-24. PMID: 10777566.
      Citations: 17     Fields:    Translation:Animals
    292. Okada H, Moriwaki K, Kalluri R, Imai H, Ban S, Takahama M, Suzuki H. Inhibition of monocyte chemoattractant protein-1 expression in tubular epithelium attenuates tubulointerstitial alteration in rat Goodpasture syndrome. Kidney Int. 2000 Mar; 57(3):927-36. PMID: 10720946.
      Citations: 5     Fields:    Translation:Animals
    293. Kalluri R, Torre A, Shield CF, Zamborsky ED, Werner MC, Suchin E, Wolf G, Helmchen UM, van den Heuvel LP, Grossman R, Aradhye S, Neilson EG. Identification of alpha3, alpha4, and alpha5 chains of type IV collagen as alloantigens for Alport posttransplant anti-glomerular basement membrane antibodies. Transplantation. 2000 Feb 27; 69(4):679-83. PMID: 10708133.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    294. Kamphaus GD, Colorado PC, Panka DJ, Hopfer H, Ramchandran R, Torre A, Maeshima Y, Mier JW, Sukhatme VP, Kalluri R. Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. J Biol Chem. 2000 Jan 14; 275(2):1209-15. PMID: 10625665.
      Citations: 126     Fields:    Translation:HumansAnimalsCells
    295. Okada H, Moriwaki K, Kalluri R, Takenaka T, Imai H, Ban S, Takahama M, Suzuki H. Osteopontin expressed by renal tubular epithelium mediates interstitial monocyte infiltration in rats. Am J Physiol Renal Physiol. 2000 Jan; 278(1):F110-21. PMID: 10644662.
      Citations: 8     Fields:    Translation:AnimalsCells
    296. Sayers R, Kalluri R, Rodgers KD, Shield CF, Meehan DT, Cosgrove D. Role for transforming growth factor-beta1 in alport renal disease progression. Kidney Int. 1999 Nov; 56(5):1662-73. PMID: 10571774.
      Citations: 36     Fields:    Translation:Animals
    297. Van Vliet AI, Van Alderwegen IE, Baelde HJ, de Heer E, Killen PD, Kalluri RK, Bruijn JA, Bergijk EC. Differential expression of collagen type IV alpha-chains in the tubulointerstitial compartment in experimental chronic serum sickness nephritis. J Pathol. 1999 Oct; 189(2):279-87. PMID: 10547587.
      Citations: 1     Fields:    Translation:Animals
    298. Wolf G, Kalluri R, Ziyadeh FN, Neilson EG, Stahl RA. Angiotensin II induces alpha3(IV) collagen expression in cultured murine proximal tubular cells. Proc Assoc Am Physicians. 1999 Jul-Aug; 111(4):357-64. PMID: 10417744.
      Citations: 6     Fields:    Translation:AnimalsCells
    299. Kalluri R. Goodpasture syndrome. Kidney Int. 1999 Mar; 55(3):1120-2. PMID: 10027952.
      Citations: 6     Fields:    Translation:HumansAnimals
    300. Lei H, Kalluri R, Furth EE, Baker AH, Strauss JF. Rat amnion type IV collagen composition and metabolism: implications for membrane breakdown. Biol Reprod. 1999 Jan; 60(1):176-82. PMID: 9858503.
      Citations: 12     Fields:    Translation:AnimalsCells
    301. Lei H, Furth EE, Kalluri R, Wakenell P, Kallen CB, Jeffrey JJ, Leboy PS, Strauss JF. Induction of matrix metalloproteinases and collagenolysis in chick embryonic membranes before hatching. Biol Reprod. 1999 Jan; 60(1):183-9. PMID: 9858504.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    302. Abbate M, Kalluri R, Corna D, Yamaguchi N, McCluskey RT, Hudson BG, Andres G, Zoja C, Remuzzi G. Experimental Goodpasture's syndrome in Wistar-Kyoto rats immunized with alpha3 chain of type IV collagen. Kidney Int. 1998 Nov; 54(5):1550-61. PMID: 9844131.
      Citations: 12     Fields:    Translation:AnimalsPHPublic Health
    303. Minto AW, Kalluri R, Togawa M, Bergijk EC, Killen PD, Salant DJ. Augmented expression of glomerular basement membrane specific type IV collagen isoforms (alpha3-alpha5) in experimental membranous nephropathy. Proc Assoc Am Physicians. 1998 May-Jun; 110(3):207-17. PMID: 9625527.
      Citations: 12     Fields:    Translation:AnimalsCells
    304. Bergijk EC, Van Alderwegen IE, Baelde HJ, de Heer E, Funabiki K, Miyai H, Killen PD, Kalluri RK, Bruijn JA. Differential expression of collagen IV isoforms in experimental glomerulosclerosis. J Pathol. 1998 Mar; 184(3):307-15. PMID: 9614384.
      Citations: 12     Fields:    Translation:AnimalsCells
    305. Meyers KE, Kinniry PA, Kalluri R, Neilson EG, Madaio MP. Human Goodpasture anti-alpha3(IV)NC1 autoantibodies share structural determinants. Kidney Int. 1998 Feb; 53(2):402-7. PMID: 9461099.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    306. Kalluri R, Gattone VH, Hudson BG. Identification and localization of type IV collagen chains in the inner ear cochlea. Connect Tissue Res. 1998; 37(1-2):143-50. PMID: 9643653.
      Citations: 8     Fields:    Translation:Animals
    307. Kalluri R, Danoff TM, Okada H, Neilson EG. Susceptibility to anti-glomerular basement membrane disease and Goodpasture syndrome is linked to MHC class II genes and the emergence of T cell-mediated immunity in mice. J Clin Invest. 1997 Nov 01; 100(9):2263-75. PMID: 9410904; PMCID: PMC508422.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    308. Kalluri R, Meyers K, Mogyorosi A, Madaio MP, Neilson EG. Goodpasture syndrome involving overlap with Wegener's granulomatosis and anti-glomerular basement membrane disease. J Am Soc Nephrol. 1997 Nov; 8(11):1795-800. PMID: 9355084.
      Citations: 7     Fields:    Translation:Humans
    309. Okada H, Danoff TM, Kalluri R, Neilson EG. Early role of Fsp1 in epithelial-mesenchymal transformation. Am J Physiol. 1997 10; 273(4):F563-74. PMID: 9362334.
      Citations: 162     Fields:    Translation:AnimalsCells
    310. Tuori AJ, Virtanen I, Aine E, Kalluri R, Miner JH, Uusitalo HM. The immunohistochemical composition of corneal basement membrane in keratoconus. Curr Eye Res. 1997 Aug; 16(8):792-801. PMID: 9255508.
      Citations: 21     Fields:    Translation:Humans
    311. Kahsai TZ, Enders GC, Gunwar S, Brunmark C, Wieslander J, Kalluri R, Zhou J, Noelken ME, Hudson BG. Seminiferous tubule basement membrane. Composition and organization of type IV collagen chains, and the linkage of alpha3(IV) and alpha5(IV) chains. J Biol Chem. 1997 Jul 04; 272(27):17023-32. PMID: 9202017.
      Citations: 33     Fields:    Translation:AnimalsCells
    312. Lohi J, Korhonen M, Leivo I, Kangas L, Tani T, Kalluri R, Miner JH, Lehto VP, Virtanen I. Expression of type IV collagen alpha1(IV)-alpha6(IV) polypeptides in normal and developing human kidney and in renal cell carcinomas and oncocytomas. Int J Cancer. 1997 Jul 03; 72(1):43-9. PMID: 9212221.
      Citations: 11     Fields:    Translation:HumansAnimals
    313. Kalluri R, Shield CF, Todd P, Hudson BG, Neilson EG. Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis. J Clin Invest. 1997 May 15; 99(10):2470-8. PMID: 9153291; PMCID: PMC508088.
      Citations: 87     Fields:    Translation:HumansCells
    314. Vargas MT, Gustilo K, D'Andrea DM, Kalluri R, Foster MH, Madaio MP. Structural features of nephritogenic lupus autoantibodies. Methods. 1997 Jan; 11(1):62-9. PMID: 8990090.
      Citations: 6     Fields:    Translation:AnimalsCells
    315. Ziyadeh FN, Kalluri R, Mogyor?si A. Early and advanced non-enzymatic glycation products in the pathogenesis of diabetic kidney disease. Exp Nephrol. 1997 Jan-Feb; 5(1):2-9. PMID: 9052842.
      Citations: 1     Fields:    Translation:HumansAnimals
    316. Lei H, Furth EE, Kalluri R, Chiou T, Tilly KI, Tilly JL, Elkon KB, Jeffrey JJ, Strauss JF. A program of cell death and extracellular matrix degradation is activated in the amnion before the onset of labor. J Clin Invest. 1996 Nov 01; 98(9):1971-8. PMID: 8903315; PMCID: PMC507640.
      Citations: 20     Fields:    Translation:AnimalsCells
    317. Boutaud AA, Kalluri R, Kahsai TZ, Noelken ME, Hudson BG. Goodpasture syndrome: selective removal of anti-alpha 3 (IV) collagen autoantibodies. A potential therapeutic alternative to plasmapheresis. Exp Nephrol. 1996 Jul-Aug; 4(4):205-12. PMID: 8864724.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    318. Thorner PS, Zheng K, Kalluri R, Jacobs R, Hudson BG. Coordinate gene expression of the alpha3, alpha4, and alpha5 chains of collagen type IV. Evidence from a canine model of X-linked nephritis with a COL4A5 gene mutation. J Biol Chem. 1996 Jun 07; 271(23):13821-8. PMID: 8662866.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    319. Kalluri R, Sun MJ, Hudson BG, Neilson EG. The Goodpasture autoantigen. Structural delineation of two immunologically privileged epitopes on alpha3(IV) chain of type IV collagen. J Biol Chem. 1996 Apr 12; 271(15):9062-8. PMID: 8621555.
      Citations: 12     Fields:    Translation:HumansCells
    320. Kalluri R, Marx M, Enders U, Stevanovic S, Giegerich G, Neilson EG, Rammensee HG, Hudson BG, Weber M, Merkel F. Autoreactive T-cells in Goodpasture's syndrome recognize the N-terminal NC1 domain on alpha 3 type IV collagen. Kidney Int. 1996 Apr; 49(4):1127-33. PMID: 8691734.
      Citations: 12     Fields:    Translation:HumansCells
    321. Kalluri R, Petrides S, Wilson CB, Tomaszewski JE, Palevsky HI, Grippi MA, Madaio MP, Neilson EG. Anti-alpha1(IV) collagen autoantibodies associated with lung adenocarcinoma presenting as the Goodpasture syndrome. Ann Intern Med. 1996 Apr 01; 124(7):651-3. PMID: 8607593.
      Citations: 5     Fields:    Translation:Humans
    322. Kalluri R, Melendez E, Rumpf KW, Sattler K, Strutz F, Neilson EG, M?ller GA. Specificity of circulating and tissue-bound autoantibodies in Goodpasture syndrome. Proc Assoc Am Physicians. 1996 Mar; 108(2):134-9. PMID: 8705733.
      Citations: 3     Fields:    Translation:HumansCells
    323. Okada H, Strutz F, Danoff TM, Kalluri R, Neilson EG. Possible mechanisms of renal fibrosis. Contrib Nephrol. 1996; 118:147-54. PMID: 8744052.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    324. Kalluri R, Wilson CB, Weber M, Gunwar S, Chonko AM, Neilson EG, Hudson BG. Identification of the alpha 3 chain of type IV collagen as the common autoantigen in antibasement membrane disease and Goodpasture syndrome. J Am Soc Nephrol. 1995 Oct; 6(4):1178-85. PMID: 8589284.
      Citations: 45     Fields:    Translation:HumansAnimals
    325. Peissel B, Geng L, Kalluri R, Kashtan C, Rennke HG, Gallo GR, Yoshioka K, Sun MJ, Hudson BG, Neilson EG, et al. Comparative distribution of the alpha 1(IV), alpha 5(IV), and alpha 6(IV) collagen chains in normal human adult and fetal tissues and in kidneys from X-linked Alport syndrome patients. J Clin Invest. 1995 Oct; 96(4):1948-57. PMID: 7560087; PMCID: PMC185832.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    326. Kalluri R, van den Heuvel LP, Smeets HJ, Schroder CH, Lemmink HH, Boutaud A, Neilson EG, Hudson BG. A COL4A3 gene mutation and post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome. Kidney Int. 1995 Apr; 47(4):1199-204. PMID: 7783419.
      Citations: 4     Fields:    Translation:Humans
    327. Kalluri R, Gattone VH, Noelken ME, Hudson BG. The alpha 3 chain of type IV collagen induces autoimmune Goodpasture syndrome. Proc Natl Acad Sci U S A. 1994 Jun 21; 91(13):6201-5. PMID: 8016138; PMCID: PMC44166.
      Citations: 23     Fields:    Translation:HumansAnimals
    328. Ding J, Kashtan CE, Fan WW, Kleppel MM, Sun MJ, Kalluri R, Neilson EG, Michael AF. A monoclonal antibody marker for Alport syndrome identifies the Alport antigen as the alpha 5 chain of type IV collagen. Kidney Int. 1994 May; 45(5):1504-6. PMID: 8072264.
      Citations: 7     Fields:    Translation:Humans
    329. Hudson BG, Kalluri R, Tryggvason K. Pathology of glomerular basement membrane nephropathy. Curr Opin Nephrol Hypertens. 1994 May; 3(3):334-9. PMID: 7922261.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    330. Kalluri R, Weber M, Netzer KO, Sun MJ, Neilson EG, Hudson BG. COL4A5 gene deletion and production of post-transplant anti-alpha 3(IV) collagen alloantibodies in Alport syndrome. Kidney Int. 1994 Mar; 45(3):721-6. PMID: 8196274.
      Citations: 4     Fields:    Translation:Humans
    331. Hudson BG, Kalluri R, Gunwar S, Noelken ME. Structure and organization of type IV collagen of renal glomerular basement membrane. Contrib Nephrol. 1994; 107:163-7. PMID: 8004963.
      Citations: 5     Fields:    Translation:HumansCells
    332. Noelken ME, Reddy GK, Kalluri R, Gunwar S, Hudson BG. The chain composition of aorta basement membrane collagen IV, localization of the chains in aorta and supramolecular assembly of the collagen IV protomers. Contrib Nephrol. 1994; 107:216-9. PMID: 8004971.
      Citations:    Fields:    Translation:AnimalsCells
    333. Reddy GK, Gunwar S, Kalluri R, Hudson BG, Noelken ME. Structure and composition of type IV collagen of bovine aorta. Biochim Biophys Acta. 1993 Jul 11; 1157(3):241-51. PMID: 8323954.
      Citations: 6     Fields:    Translation:AnimalsCells
    334. Neilson EG, Kalluri R, Sun MJ, Gunwar S, Danoff T, Mariyama M, Myers JC, Reeders ST, Hudson BG. Specificity of Goodpasture autoantibodies for the recombinant noncollagenous domains of human type IV collagen. J Biol Chem. 1993 Apr 25; 268(12):8402-5. PMID: 8473281.
      Citations: 12     Fields:    Translation:HumansCells
    335. Hudson BG, Kalluri R, Gunwar S, Noelken ME, Mariyama M, Reeders ST. Molecular characteristics of the Goodpasture autoantigen. Kidney Int. 1993 Jan; 43(1):135-9. PMID: 7679455.
      Citations: 10     Fields:    Translation:HumansCells
    336. Hudson BG, Kalluri R, Gunwar S, Weber M, Ballester F, Hudson JK, Noelken ME, Sarras M, Richardson WR, Saus J, et al. The pathogenesis of Alport syndrome involves type IV collagen molecules containing the alpha 3(IV) chain: evidence from anti-GBM nephritis after renal transplantation. Kidney Int. 1992 Jul; 42(1):179-87. PMID: 1635348.
      Citations: 10     Fields:    Translation:Humans
    337. Mariyama M, Kalluri R, Hudson BG, Reeders ST. The alpha 4(IV) chain of basement membrane collagen. Isolation of cDNAs encoding bovine alpha 4(IV) and comparison with other type IV collagens. J Biol Chem. 1992 Jan 15; 267(2):1253-8. PMID: 1370461.
      Citations: 11     Fields:    Translation:AnimalsCells
    338. Kalluri R, Gunwar S, Reeders ST, Morrison KC, Mariyama M, Ebner KE, Noelken ME, Hudson BG. Goodpasture syndrome. Localization of the epitope for the autoantibodies to the carboxyl-terminal region of the alpha 3(IV) chain of basement membrane collagen. J Biol Chem. 1991 Dec 15; 266(35):24018-24. PMID: 1721062.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    339. Gunwar S, Ballester F, Kalluri R, Timoneda J, Chonko AM, Edwards SJ, Noelken ME, Hudson BG. Glomerular basement membrane. Identification of dimeric subunits of the noncollagenous domain (hexamer) of collagen IV and the Goodpasture antigen. J Biol Chem. 1991 Aug 15; 266(23):15318-24. PMID: 1869555.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    340. Gunwar S, Bejarano PA, Kalluri R, Langeveld JP, Wisdom BJ, Noelken ME, Hudson BG. Alveolar basement membrane: molecular properties of the noncollagenous domain (hexamer) of collagen IV and its reactivity with Goodpasture autoantibodies. Am J Respir Cell Mol Biol. 1991 Aug; 5(2):107-12. PMID: 1892641.
      Citations: 10     Fields:    Translation:HumansAnimals
    341. Starting the scar. Nature Medicine. 17:1053.
    342. Partial Epithelial-to-Mesenchymal Transition and Other New Mechanisms of Kidney Fibrosis. Trends in Endocrinology and Metabolism.
    343. Possible mechanisms of kidney repair. Fibrogenesis and Tissue Repair. 2.
    344. Thrombospondin-1 deficiency causes a shift from fibroproliferative to inflammatory kidney disease and delays onset of renal failure. American Journal of Pathology. 184:2687-2698.
    345. Erratum. Proceedings of the National Academy of Sciences of the United States of America. 91:9195.
    346. Endogenous inhibitors of angiogenesis. 215-231.
    347. Conversion of vascular endothelial cells into multipotent stem-like cells. Nature Medicine.
    348. Kidney International. 91:157-176.
    349. Epithelial-mesenchymal transitions - New insights into signaling, development and pathogenesis. Cells Tissues Organs. 185:5-6.
    350. The basics of epithelial-mesenchymal transition (The Journal of Clinical Investigation (2009) 119, 6, (1420-1428) DOI. Journal of Clinical Investigation. 120:1786.
    351. Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression. Nature Medicine. 22:497-505.
    352. Cardiac fibrosis. 389-404.
    353. Induction of Tet3-dependent Epigenetic Remodeling by Low-dose Hydralazine Attenuates Progression of Chronic Kidney Disease. EBioMedicine. 2:19-36.
    354. Erratum. Nature Medicine. 17:514.
    355. The biology and function of exosomes in cancer. Journal of Clinical Investigation. 126:1208-1215.
    356. Erratum. Nature Cell Biology. 16:1125.
    357. Molecular and genetic basis of alport syndrome. 151-171.
    358. Genome-wide profiling of p53-regulated enhancer RNAs uncovers a subset of enhancers controlled by a lncRNA. Nature Communications. 6.
    359. The biology and function of fibroblasts in cancer. Nature Reviews Cancer. 16:582-598.
    360. Erratum to Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival [Cancer Cell 25, 719-734; (2014)]. Cancer Cell. 28:831-833.
    361. Basement membrane derived inhibitors of angiogenesis. 121-127.
    362. Mass Spectrometry and Antibody-Based Characterization of Blood Vessels from Brachylophosaurus canadensis. Journal of Proteome Research. 14:5252-5262.
    363. Physiology of the renal interstitium. Clinical Journal of the American Society of Nephrology. 10:1831-1840.
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