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XIAOPING SU

TitleAssociate Professor
InstitutionMD Anderson
DepartmentBioinformatics & Computational Biology
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fiskus W, Piel J, Collins MP, Hentemann M, Cuglievan B, Mill CP, Birdwell C, Das K, Davis JA, Hou H, Jain A, Malovannaya A, Kadia TM, Daver NG, Sasaki K, Takahashi K, Hammond D, Reville PK, Wang J, Loghavi S, Sen R, Ruan X, Su X, Flores L, DiNardo CD, Bhalla KN. BRG1/BRM inhibitor targets AML stem cells and exerts superior preclinical efficacy combined with BET or Menin inhibitor. Blood. 2024 Feb 16. PMID: 38437498.
      Citations:    Fields:    
    2. Dibra D, Xiong S, Moyer SM, El-Naggar AK, Qi Y, Su X, Kong EK, Korkut A, Lozano G. Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo. Sci Adv. 2024 Feb 16; 10(7):eadk1835. PMID: 38354236; PMCID: PMC10866549.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Dibra D, Gagea M, Qi Y, Chau GP, Su X, Lozano G, Dibra D, Gagea M, Qi Y, Chau GP, Su X, Lozano G. p53R245W Mutation Fuels Cancer Initiation and Metastases in NASH-driven Liver Tumorigenesis. Cancer Res Commun. 2023 12 29; 3(12):2640-2652. PMID: 38047594; PMCID: PMC10761659.
      Citations:    Translation:Animals
    4. Su X, Lu X, Bazai SK, Dainese L, Verschuur A, Dumont B, Mouawad R, Xu L, Cheng W, Yan F, Irtan S, Lindner V, Paillard C, Le Bouc Y, Coulomb A, Malouf GG. Delineating the interplay between oncogenic pathways and immunity in anaplastic Wilms tumors. Nat Commun. 2023 Nov 30; 14(1):7884. PMID: 38036539; PMCID: PMC10689851.
      Citations:    Fields:    Translation:Humans
    5. Mistretta B, Rankothgedera S, Castillo M, Rao M, Holloway K, Bhardwaj A, El Noafal M, Albarracin C, El-Zein R, Rezaei H, Su X, Akbani R, Shao XM, Czerniecki BJ, Karchin R, Bedrosian I, Gunaratne PH. Chimeric RNAs reveal putative neoantigen peptides for developing tumor vaccines for breast cancer. Front Immunol. 2023; 14:1188831. PMID: 37744342; PMCID: PMC10512078.
      Citations:    Fields:    Translation:HumansAnimals
    6. Sun C, Qi Y, Fowlkes N, Lazic N, Su X, Lozano G, Wasylishen AR. The histone chaperone function of Daxx is dispensable for embryonic development. Cell Death Dis. 2023 08 26; 14(8):565. PMID: 37633949; PMCID: PMC10460429.
      Citations: 1     Fields:    Translation:AnimalsCells
    7. Dibra D, Moyer SM, El-Naggar AK, Qi Y, Su X, Lozano G. Triple-negative breast tumors are dependent on mutant p53 for growth and survival. Proc Natl Acad Sci U S A. 2023 08 22; 120(34):e2308807120. PMID: 37579145; PMCID: PMC10450424.
      Citations: 5     Fields:    Translation:HumansAnimals
    8. Chachad D, Patel LR, Recio CV, Pourebrahim R, Whitley EM, Wang W, Su X, Xu A, Lee DF, Lozano G. Unique Transcriptional Profiles Underlie Osteosarcomagenesis Driven by Different p53 Mutants. Cancer Res. 2023 07 14; 83(14):2297-2311. PMID: 37205631; PMCID: PMC10524763.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    9. Gencel-Augusto J, Su X, Qi Y, Whitley EM, Pant V, Xiong S, Shah V, Lin J, Perez E, Fiorotto ML, Mahmud I, Jain AK, Lorenzi PL, Navin NE, Richie ER, Lozano G. Dimeric p53 Mutant Elicits Unique Tumor-Suppressive Activities through an Altered Metabolic Program. Cancer Discov. 2023 05 04; 13(5):1230-1249. PMID: 37067911; PMCID: PMC10164062.
      Citations: 3     Fields:    Translation:Animals
    10. Fiskus W, Mill CP, Birdwell C, Davis JA, Das K, Boettcher S, Kadia TM, DiNardo CD, Takahashi K, Loghavi S, Soth MJ, Heffernan T, McGeehan GM, Ruan X, Su X, Vakoc CR, Daver N, Bhalla KN. Targeting of epigenetic co-dependencies enhances anti-AML efficacy of Menin inhibitor in AML with MLL1-r or mutant NPM1. Blood Cancer J. 2023 04 13; 13(1):53. PMID: 37055414; PMCID: PMC10102188.
      Citations:    Fields:    Translation:Humans
    11. Stitzlein LM, Gangadharan A, Walsh LM, Nam D, Espejo AB, Singh MM, Patel KH, Lu Y, Su X, Ezhilarasan R, Gumin J, Singh S, Sulman E, Lang FF, Chandra J. Comparison of pharmacological inhibitors of lysine-specific demethylase 1 in glioblastoma stem cells reveals inhibitor-specific efficacy profiles. Front Neurol. 2023; 14:1112207. PMID: 37082446; PMCID: PMC10111022.
      Citations:    
    12. Konopleva M, DiNardo C, Bhagat T, Baran N, Lodi A, Saxena K, Cai T, Su X, Skwarska A, Guerra V, Kuruvilla V, Konoplev S, Gordon-Mitchell S, Pradhan K, Aluri S, Collins M, Sweeney S, Busquet J, Rathore A, Deng Q, Green M, Grant S, Demo S, Choudhary G, Sahu S, Agarwal B, Spodek M, Thiruthuvanathan V, Will B, Steidl U, Tippett G, Burger J, Borthakur G, Jabbour E, Pemmaraju N, Kadia T, Komblau S, Daver N, Naqvi K, Short N, Garcia-Manero G, Tiziani S, Verma A. Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: Clinical efficacy and correlative analyses. Res Sq. 2023 Feb 23. PMID: 36865338; PMCID: PMC9980221.
      Citations:    
    13. Xiong S, Chachad D, Zhang Y, Gencel-Augusto J, Sirito M, Pant V, Yang P, Sun C, Chau G, Qi Y, Su X, Whitley EM, El-Naggar AK, Lozano G. Differential Gain-of-Function Activity of Three p53 Hotspot Mutants In Vivo. Cancer Res. 2022 05 16; 82(10):1926-1936. PMID: 35320355; PMCID: PMC9117479.
      Citations:    Fields:    Translation:AnimalsCells
    14. Cai T, Black KL, Skwarska A, Naqvi AS, Taylor D, Zhao M, Yuan Q, Sugita M, Zhang Q, Galetto R, Cavazos A, Han L, Kuruvilla V, Ma H, Weng C, Liu CG, Liu X, Konoplev S, Gu J, Tang G, Su X, Al-Atrash G, Ciurea S, Neelapu SS, Lane AA, Kantarjian H, Guzman ML, Pemmaraju N, Smith J, Thomas-Tikhonenko A, Konopleva M, Gouble A, Filipe S. Targeting CD123 in blastic plasmacytoid dendritic cell neoplasm using allogeneic anti-CD123 CAR T cells. Nat Commun. 2022 04 28; 13(1):2228. PMID: 35484100; PMCID: PMC9051102.
      Citations:    Fields:    Translation:HumansAnimalsCells
    15. Evans KW, Yuca E, Scott SS, Zhao M, Paez Arango N, Cruz Pico CX, Saridogan T, Shariati M, Class CA, Bristow CA, Vellano CP, Zheng X, Gonzalez-Angulo AM, Su X, Tapia C, Chen K, Akcakanat A, Lim B, Tripathy D, Yap TA, Francesco MED, Draetta GF, Jones P, Heffernan TP, Marszalek JR, Meric-Bernstam F. Oxidative Phosphorylation Is a Metabolic Vulnerability in Chemotherapy-Resistant Triple-Negative Breast Cancer. Cancer Res. 2021 11 01; 81(21):5572-5581. PMID: 34518211; PMCID: PMC8563442.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    16. Villodre ES, Hu X, Larson R, Finetti P, Gomez K, Balema W, Stecklein SR, Santiago-Sanchez G, Krishnamurthy S, Song J, Su X, Ueno NT, Tripathy D, Van Laere S, Woodward WA, Debeb BG, Bertucci F, Vivas-Mej?a P. Lipocalin 2 promotes inflammatory breast cancer tumorigenesis and skin invasion. Mol Oncol. 2021 10; 15(10):2752-2765. PMID: 34342930; PMCID: PMC8486564.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    17. Wiele AJ, Surasi DS, Rao P, Sircar K, Su X, Bathala TK, Shah AY, Jonasch E, Cataldo VD, Genovese G, Karam JA, Wood CG, Tannir NM, Msaouel P. Efficacy and Safety of Bevacizumab Plus Erlotinib in Patients with Renal Medullary Carcinoma. Cancers (Basel). 2021 Apr 30; 13(9). PMID: 33946504; PMCID: PMC8124338.
      Citations: 2     
    18. Petros FG, Choi W, Qi Y, Moss T, Li R, Su X, Guo CC, Czerniak B, Dinney C, McConkey DJ, Matin SF. Expression Analysis of Same-Patient Metachronous and Synchronous Upper Tract and Bladder Urothelial Carcinoma. J Urol. 2021 09; 206(3):548-557. PMID: 33881933.
      Citations: 3     Fields:    Translation:Humans
    19. Su X, Lu X, Bazai SK, Yao H, Davidson I, Tannir NN, Yan F, Malouf GG, Comp?rat E, Mouawad R, Roupr?t M, Spano JP, Khayat D. Comprehensive integrative profiling of upper tract urothelial carcinomas. Genome Biol. 2021 01 04; 22(1):7. PMID: 33397444; PMCID: PMC7780630.
      Citations: 8     Fields:    Translation:HumansCells
    20. Moyer SM, Wasylishen AR, Qi Y, Fowlkes N, Su X, Lozano G. p53 drives a transcriptional program that elicits a non-cell-autonomous response and alters cell state in vivo. Proc Natl Acad Sci U S A. 2020 09 22; 117(38):23663-23673. PMID: 32900967; PMCID: PMC7519296.
      Citations: 10     Fields:    Translation:AnimalsCells
    21. Wasylishen AR, Sun C, Moyer SM, Qi Y, Chau GP, Aryal NK, McAllister F, Kim MP, Barton MC, Estrella JS, Su X, Lozano G. Daxx maintains endogenous retroviral silencing and restricts cellular plasticity in vivo. Sci Adv. 2020 08; 6(32):eaba8415. PMID: 32821827; PMCID: PMC7406367.
      Citations: 6     Fields:    Translation:AnimalsCells
    22. Msaouel P, Su X, Yao H, Tripathi DN, Soeung M, Gao J, Rao P, Coarfa C, Creighton CJ, Bertocchio JP, Kunnimalaiyaan S, Multani AS, Blando J, He R, Shapiro DD, Perelli L, Srinivasan S, Carbone F, Karki M, Seervai RNH, Lopez-Terrada D, Cheng EH, Tang X, Lu W, Wistuba II, Thompson TC, Giuliani V, Schlacher K, Carugo A, Heffernan TP, Sharma P, Karam JA, Wood CG, Walker CL, Genovese G, Tannir NM, Malouf GG, Pili? PG, Vokshi BH, Davidson I. Comprehensive Molecular Characterization Identifies Distinct Genomic and Immune Hallmarks of Renal Medullary Carcinoma. Cancer Cell. 2020 05 11; 37(5):720-734.e13. PMID: 32359397; PMCID: PMC7288373.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    23. Wasylishen AR, Sun C, Chau GP, Qi Y, Su X, Kim MP, Estrella JS, Lozano G. Men1 maintains exocrine pancreas homeostasis in response to inflammation and oncogenic stress. Proc Natl Acad Sci U S A. 2020 03 24; 117(12):6622-6629. PMID: 32156729; PMCID: PMC7104337.
      Citations: 6     Fields:    Translation:Animals
    24. Chen J, Mitra A, Li S, Song S, Nguyen BN, Chen JS, Shin JH, Gough NR, Lin P, Obias V, He AR, Yao Z, Malta TM, Noushmehr H, Latham PS, Su X, Rashid A, Mishra B, Wu RC, Mishra L. Targeting the E3 Ubiquitin Ligase PJA1 Enhances Tumor-Suppressing TGF? Signaling. Cancer Res. 2020 05 01; 80(9):1819-1832. PMID: 32127355; PMCID: PMC7704101.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    25. Zhao M, Zhuo ML, Zheng X, Su X, Meric-Bernstam F. Correction: FGFR1? is a driver isoform of FGFR1 alternative splicing in breast cancer cells. Oncotarget. 2019 Dec 10; 10(65):7014-7015. PMID: 31857856; PMCID: PMC6916757.
      Citations:    Fields:    
    26. Chen J, Gingold JA, Su X. Immunomodulatory TGF-? Signaling in Hepatocellular Carcinoma. Trends Mol Med. 2019 11; 25(11):1010-1023. PMID: 31353124.
      Citations: 64     Fields:    Translation:HumansCells
    27. Carugo A, Minelli R, Sapio L, Soeung M, Carbone F, Robinson FS, Tepper J, Chen Z, Lovisa S, Svelto M, Amin S, Srinivasan S, Del Poggetto E, Loponte S, Puca F, Dey P, Su X, Li L, Lopez-Terrada D, Rakheja D, Lazar AJ, Netto GJ, Rao P, Maitra A, Tripathi DN, Walker CL, Karam JA, Heffernan TP, Viale A, Roberts CWM, Msaouel P, Tannir NM, Draetta GF, Genovese G, Malouf GG, Sgambato A. p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors. Cancer Cell. 2019 02 11; 35(2):204-220.e9. PMID: 30753823; PMCID: PMC7876656.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    28. Zhao M, Zhuo ML, Zheng X, Su X, Meric-Bernstam F. FGFR1? is a driver isoform of FGFR1 alternative splicing in breast cancer cells. Oncotarget. 2019 Jan 01; 10(1):30-44. PMID: 30713601; PMCID: PMC6343755.
      Citations: 6     Fields:    
    29. Bose P, Nazha A, Komrokji RS, Patel KP, Pierce SA, Al-Ali N, Sochacki A, Shaver A, Ma W, Su X, Daver NG, DiNardo CD, Garcia-Manero G, Loghavi S, Bueso-Ramos C, Kantarjian HM, Sekeres MA, Savona MR, Maciejewski JP, Verstovsek S. Mutational landscape of myelodysplastic/myeloproliferative neoplasm-unclassifiable. Blood. 2018 11 08; 132(19):2100-2103. PMID: 30242087; PMCID: PMC6236463.
      Citations: 17     Fields:    Translation:Humans
    30. Chen J, Zaidi S, Rao S, Chen JS, Phan L, Farci P, Su X, Shetty K, White J, Zamboni F, Wu X, Rashid A, Pattabiraman N, Mazumder R, Horvath A, Wu RC, Li S, Xiao C, Deng CX, Wheeler DA, Mishra B, Akbani R, Mishra L. Analysis of Genomes and Transcriptomes of Hepatocellular Carcinomas Identifies Mutations and Gene Expression Changes in the Transforming Growth Factor-? Pathway. Gastroenterology. 2018 01; 154(1):195-210. PMID: 28918914; PMCID: PMC6192529.
      Citations: 47     Fields:    Translation:HumansCells
    31. Horstmann N, Sahasrabhojane P, Yao H, Su X, Shelburne SA. Use of a Phosphorylation Site Mutant To Identify Distinct Modes of Gene Repression by the Control of Virulence Regulator (CovR) in Streptococcus pyogenes. J Bacteriol. 2017 09 15; 199(18). PMID: 28289082; PMCID: PMC5573087.
      Citations: 11     Fields:    Translation:Cells
    32. Su X, Zhang J, Thompson EJ, Gowrishankar B, Houldsworth J, Weinstein JN, Tost J, Broom BM, Tannir NM, Mouawad R, Comp?rat E, Roupr?t M, Allanic F, Parra J, Bitker MO, Khayat D, Spano JP, Malouf GG. NSD1 Inactivation and SETD2 Mutation Drive a Convergence toward Loss of Function of H3K36 Writers in Clear Cell Renal Cell Carcinomas. Cancer Res. 2017 09 15; 77(18):4835-4845. PMID: 28754676; PMCID: PMC6211291.
      Citations: 17     Fields:    Translation:HumansCells
    33. Dai F, Lee H, Zhang Y, Zhuang L, Yao H, Xi Y, Xiao ZD, You MJ, Li W, Su X, Gan B. BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response. Proc Natl Acad Sci U S A. 2017 03 21; 114(12):3192-3197. PMID: 28275095; PMCID: PMC5373337.
      Citations: 42     Fields:    Translation:AnimalsCells
    34. Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong LN, Katz LH, Shetty K, Rashid A, Su X, White J, Li L, Wang AY, Blechacz B, Raju GS, Davila M, Nguyen BN, Stroehlein JR, Chen J, Kim SS, Levin H, Machida K, Tsukamoto H, Michaely P, Tzatsos A, Mishra B, Amdur R, Mishra L. Loss of the transforming growth factor-? effector ?2-Spectrin promotes genomic instability. Hepatology. 2017 02; 65(2):678-693. PMID: 28114741; PMCID: PMC5432427.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    35. Ochoa AE, Choi W, Su X, Siefker-Radtke A, Czerniak B, Dinney C, McConkey DJ. Specific micro-RNA expression patterns distinguish the basal and luminal subtypes of muscle-invasive bladder cancer. Oncotarget. 2016 Dec 06; 7(49):80164-80174. PMID: 27845906; PMCID: PMC5348311.
      Citations: 23     Fields:    Translation:HumansCells
    36. Matre P, Velez J, Jacamo R, Qi Y, Su X, Cai T, Chan SM, Lodi A, Sweeney SR, Ma H, Davis RE, Baran N, Haferlach T, Su X, Flores ER, Gonzalez D, Konoplev S, Samudio I, DiNardo C, Majeti R, Schimmer AD, Li W, Wang T, Tiziani S, Konopleva M. Inhibiting glutaminase in acute myeloid leukemia: metabolic dependency of selected AML subtypes. Oncotarget. 2016 Nov 29; 7(48):79722-79735. PMID: 27806325; PMCID: PMC5340236.
      Citations: 70     Fields:    Translation:Humans
    37. Shen C, Meric-Bernstam F, Su X, Mendelsohn J, Giordano S. Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel. Oncotarget. 2016 Nov 01; 7(44):71686-71695. PMID: 27634896; PMCID: PMC5342111.
      Citations: 5     Fields:    Translation:Humans
    38. Chakravarthy A, Henderson S, Thirdborough SM, Ottensmeier CH, Su X, Lechner M, Feber A, Thomas GJ, Fenton TR. Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx. J Clin Oncol. 2016 12; 34(34):4132-4141. PMID: 27863190; PMCID: PMC5477823.
      Citations: 55     Fields:    Translation:HumansCells
    39. Chitsazzadeh V, Coarfa C, Drummond JA, Nguyen T, Joseph A, Chilukuri S, Charpiot E, Adelmann CH, Ching G, Nguyen TN, Nicholas C, Thomas VD, Migden M, MacFarlane D, Thompson E, Shen J, Takata Y, McNiece K, Polansky MA, Abbas HA, Rajapakshe K, Gower A, Spira A, Covington KR, Xiao W, Gunaratne P, Pickering C, Frederick M, Myers JN, Shen L, Yao H, Su X, Rapini RP, Wheeler DA, Hawk ET, Flores ER, Tsai KY. Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates. Nat Commun. 2016 08 30; 7:12601. PMID: 27574101; PMCID: PMC5013636.
      Citations: 50     Fields:    Translation:HumansAnimals
    40. Chen J, Raju GS, Jogunoori W, Menon V, Majumdar A, Chen JS, Gi YJ, Jeong YS, Phan L, Belkin M, Gu S, Kundra S, Mistry NA, Zhang J, Su X, Li S, Lin SH, Javle M, McMurray JS, Rahlfs TF, Mishra B, White J, Rashid A, Beauchemin N, Weston BR, Shafi MA, Stroehlein JR, Davila M, Akbani R, Weinstein JN, Wu X, Mishra L. Mutational Profiles Reveal an Aberrant TGF-?-CEA Regulated Pathway in Colon Adenomas. PLoS One. 2016; 11(4):e0153933. PMID: 27100181; PMCID: PMC4839765.
      Citations: 10     Fields:    Translation:HumansCells
    41. Jiang Y, Zhang J, Zheng X, Chen Y, Thompson EJ, Weinstein JN, Yuan Y, Broaddus R, Tannir NM, Lu KH, Su X, Malouf GG, Spano JP, Khayat D. Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations. Oncotarget. 2015 Nov 24; 6(37):39865-76. PMID: 26431491; PMCID: PMC4741866.
      Citations: 10     Fields:    Translation:HumansCells
    42. Ryan M, Wong WC, Brown R, Akbani R, Su X, Broom B, Melott J, Weinstein J. TCGASpliceSeq a compendium of alternative mRNA splicing in cancer. Nucleic Acids Res. 2016 Jan 04; 44(D1):D1018-22. PMID: 26602693; PMCID: PMC4702910.
      Citations: 163     Fields:    Translation:Cells
    43. Flores AR, Sahasrabhojane P, Yao H, Su X, Ajami NJ, Holder ME, Petrosino JF, Thompson E, Margarit Y Ros I, Rosini R, Grandi G, Horstmann N, Teatero S, McGeer A, Fittipaldi N, Rappuoli R, Baker CJ, Shelburne SA, Galloway-Pe?a J, Salda?a M. Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):6431-6. PMID: 25941374; PMCID: PMC4443349.
      Citations: 47     Fields:    Translation:HumansCells
    44. Singh MM, Johnson B, Venkatarayan A, Flores ER, Zhang J, Su X, Barton M, Lang F, Chandra J. Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma. Neuro Oncol. 2015 Nov; 17(11):1463-73. PMID: 25795306; PMCID: PMC4648298.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    45. Horstmann N, Sahasrabhojane P, Ajami NJ, Flores AR, Sumby P, Liu CG, Yao H, Su X, Thompson E, Shelburne SA, Salda?a M. Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus. Infect Immun. 2015 Mar; 83(3):1068-77. PMID: 25561708; PMCID: PMC4333468.
      Citations: 30     Fields:    Translation:Cells
    46. Su X, Chen Y, Zhang J, Yao H, Valero V, Weinstein JN, Meric-Bernstam F, Esteva FJ, Malouf GG, Spano JP, Khayat D. Comprehensive analysis of long non-coding RNAs in human breast cancer clinical subtypes. Oncotarget. 2014 Oct 30; 5(20):9864-76. PMID: 25296969; PMCID: PMC4259443.
      Citations: 106     Fields:    Translation:HumansCells
    47. Choi W, Czerniak B, Ochoa A, Su X, Siefker-Radtke A, Dinney C, McConkey DJ. Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer. Nat Rev Urol. 2014 Jul; 11(7):400-10. PMID: 24960601.
      Citations: 111     Fields:    Translation:Humans
    48. Horstmann N, Sahasrabhojane P, Yao H, Su X, Thompson E, Koller A, Shelburne SA, Salda?a M. Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis. PLoS Pathog. 2014 May; 10(5):e1004088. PMID: 24788524; PMCID: PMC4006921.
      Citations: 44     Fields:    Translation:AnimalsCells
    49. Shelburne SA, Sahasrabhojane P, Saldana M, Yao H, Su X, Horstmann N, Thompson E, Flores AR. Streptococcus mitis strains causing severe clinical disease in cancer patients. Emerg Infect Dis. 2014 May; 20(5):762-71. PMID: 24750901; PMCID: PMC4012796.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    50. Meric-Bernstam F, Frampton GM, Ferrer-Lozano J, Yelensky R, Wang Y, Palmer GA, Ross JS, Miller VA, Su X, Eroles P, Barrera JA, Burgues O, Lluch AM, Zheng X, Sahin A, Stephens PJ, Mills GB, Cronin MT, Gonzalez-Angulo AM, P?rez-Fidalgo JA. Concordance of genomic alterations between primary and recurrent breast cancer. Mol Cancer Ther. 2014 May; 13(5):1382-9. PMID: 24608573; PMCID: PMC4348062.
      Citations: 50     Fields:    Translation:Humans
    51. Cancer Genome Atlas Research Network. Comprehensive molecular characterization of urothelial bladder carcinoma. Nature. 2014 Mar 20; 507(7492):315-22. PMID: 24476821; PMCID: PMC3962515.
      Citations: 1166     Fields:    Translation:HumansCells
    52. Mittendorf EA, Philips AV, Meric-Bernstam F, Qiao N, Wu Y, Harrington S, Su X, Wang Y, Gonzalez-Angulo AM, Akcakanat A, Chawla A, Curran M, Hwu P, Sharma P, Litton JK, Molldrem JJ, Alatrash G. PD-L1 expression in triple-negative breast cancer. Cancer Immunol Res. 2014 Apr; 2(4):361-70. PMID: 24764583; PMCID: PMC4000553.
      Citations: 431     Fields:    Translation:HumansCells
    53. How-Kit A, Su X, Charbel C, Fontaine RH, Malouf GG, Picard A, Kadlub N, El-Murr N, Coulomb-L'Hermine A, Tost J, Mourah S, Aractingi S, Gu?gan S. NRAS mutation is the sole recurrent somatic mutation in large congenital melanocytic nevi. J Invest Dermatol. 2014 Apr; 134(4):1067-1074. PMID: 24129063.
      Citations: 46     Fields:    Translation:HumansCells
    54. Cancer Genome Atlas Research Network, Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 2013 Oct; 45(10):1113-20. PMID: 24071849; PMCID: PMC3919969.
      Citations: 2555     Fields:    Translation:Humans
    55. Malouf GG, Monzon FA, Escudier B, Su X, Yao H, Tamboli P, Lopez-Terrada D, Picken M, Garcia M, Multani AS, Pathak S, Wood CG, Tannir NM, Couturier J, Molini? V, Camparo P. Genomic heterogeneity of translocation renal cell carcinoma. Clin Cancer Res. 2013 Sep 01; 19(17):4673-84. PMID: 23817689; PMCID: PMC3882157.
      Citations: 29     Fields:    Translation:HumansCells
    56. Khoury JD, Tannir NM, Williams MD, Chen Y, Yao H, Zhang J, Thompson EJ, TCGA Network, Meric-Bernstam F, Medeiros LJ, Weinstein JN, Su X. Landscape of DNA virus associations across human malignant cancers: analysis of 3,775 cases using RNA-Seq. J Virol. 2013 Aug; 87(16):8916-26. PMID: 23740984; PMCID: PMC3754044.
      Citations: 94     Fields:    Translation:HumansCells
    57. Toledo RA, Qin Y, Srikantan S, Morales NP, Li Q, Deng Y, Kim SW, Pereira MA, Toledo SP, Su X, Aguiar RC, Dahia PL. In vivo and in vitro oncogenic effects of HIF2A mutations in pheochromocytomas and paragangliomas. Endocr Relat Cancer. 2013 Jun; 20(3):349-59. PMID: 23533246; PMCID: PMC5944295.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    58. Shieh A, Ward AF, Donlan KL, Harding-Theobald ER, Xu J, Mullighan CG, Zhang C, Chen SC, Su X, Downing JR, Bollag GE, Shannon KM. Defective K-Ras oncoproteins overcome impaired effector activation to initiate leukemia in vivo. Blood. 2013 Jun 13; 121(24):4884-93. PMID: 23637129; PMCID: PMC3682340.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    59. Chen Y, Yao H, Thompson EJ, Tannir NM, Weinstein JN, Su X. VirusSeq: software to identify viruses and their integration sites using next-generation sequencing of human cancer tissue. Bioinformatics. 2013 Jan 15; 29(2):266-7. PMID: 23162058; PMCID: PMC3546792.
      Citations: 85     Fields:    Translation:HumansCells
    60. Gruber TA, Larson Gedman A, Zhang J, Koss CS, Marada S, Ta HQ, Chen SC, Su X, Ogden SK, Dang J, Wu G, Gupta V, Andersson AK, Pounds S, Shi L, Easton J, Barbato MI, Mulder HL, Manne J, Wang J, Rusch M, Ranade S, Ganti R, Parker M, Ma J, Radtke I, Ding L, Cazzaniga G, Biondi A, Kornblau SM, Ravandi F, Kantarjian H, Nimer SD, Ley TJ, Ballerini P, Shurtleff S, Tomizawa D, Adachi S, Hayashi Y, Tawa A, Shih LY, Liang DC, Rubnitz JE, Pui CH, Mardis ER, Wilson RK, Downing JR, D?hner K, D?hner H. An Inv(16)(p13.3q24.3)-encoded CBFA2T3-GLIS2 fusion protein defines an aggressive subtype of pediatric acute megakaryoblastic leukemia. Cancer Cell. 2012 Nov 13; 22(5):683-97. PMID: 23153540; PMCID: PMC3547667.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    61. Edelmann J, Holzmann K, Miller F, Winkler D, Zenz T, Bullinger L, Gerhardinger A, Bloehdorn J, Radtke I, Su X, Ma J, Pounds S, Hallek M, Lichter P, Korbel J, Busch R, Mertens D, Downing JR, Stilgenbauer S, B?hler A, K?hn MW, D?hner H. High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations. Blood. 2012 Dec 06; 120(24):4783-94. PMID: 23047824.
      Citations: 94     Fields:    Translation:HumansCells
    62. Roberts KG, Morin RD, Zhang J, Hirst M, Zhao Y, Su X, Chen SC, Payne-Turner D, Churchman ML, Harvey RC, Chen X, Kasap C, Yan C, Becksfort J, Finney RP, Teachey DT, Maude SL, Tse K, Moore R, Jones S, Mungall K, Birol I, Edmonson MN, Hu Y, Buetow KE, Chen IM, Carroll WL, Wei L, Ma J, Kleppe M, Levine RL, Garcia-Manero G, Larsen E, Shah NP, Devidas M, Reaman G, Smith M, Paugh SW, Evans WE, Grupp SA, Jeha S, Pui CH, Gerhard DS, Downing JR, Willman CL, Loh M, Hunger SP, Marra MA, Mullighan CG. Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia. Cancer Cell. 2012 Aug 14; 22(2):153-66. PMID: 22897847; PMCID: PMC3422513.
      Citations: 305     Fields:    Translation:HumansAnimalsCells
    63. Su X, Zhang L, Zhang J, Meric-Bernstam F, Weinstein JN. PurityEst: estimating purity of human tumor samples using next-generation sequencing data. Bioinformatics. 2012 Sep 01; 28(17):2265-6. PMID: 22743227; PMCID: PMC3426843.
      Citations: 35     Fields:    Translation:HumansCells
    64. Radtke I, Bullinger L, Goorha S, Cheng J, Edelmann J, Gohlke J, Su X, Paschka P, Pounds S, Ganser A, Quessar A, Ribeiro R, Gaidzik VI, Shurtleff S, Holzmann K, Ma J, Schlenk RF, Rubnitz JE, Downing JR, K?hn MW, Krauter J, Kr?nke J, D?hner K, D?hner H. High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations. Blood. 2012 Mar 08; 119(10):e67-75. PMID: 22234698; PMCID: PMC3311263.
      Citations: 35     Fields:    Translation:Humans
    65. Song G, Clark C, Key L, Liu P, Mehrpooya M, Stow P, Su X, Shurtleff S, Pui CH, Downing JR, Campana D, Coustan-Smith E. New markers for minimal residual disease detection in acute lymphoblastic leukemia. Blood. 2011 Jun 09; 117(23):6267-76. PMID: 21487112; PMCID: PMC3122946.
      Citations: 112     Fields:    Translation:Humans
    66. Radtke I, Mullighan CG, Ishii M, Su X, Cheng J, Ma J, Ganti R, Cai Z, Goorha S, Pounds SB, Cao X, Obert C, Armstrong J, Zhang J, Song G, Ribeiro RC, Rubnitz JE, Raimondi SC, Shurtleff SA, Downing JR. Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia. Proc Natl Acad Sci U S A. 2009 Aug 04; 106(31):12944-9. PMID: 19651601; PMCID: PMC2716382.
      Citations: 87     Fields:    Translation:Humans
    67. Mullighan CG, Zhang J, Harvey RC, Collins-Underwood JR, Schulman BA, Phillips LA, Tasian SK, Loh ML, Su X, Liu W, Devidas M, Atlas SR, Chen IM, Clifford RJ, Gerhard DS, Carroll WL, Reaman GH, Smith M, Downing JR, Hunger SP, Willman CL. JAK mutations in high-risk childhood acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2009 Jun 09; 106(23):9414-8. PMID: 19470474; PMCID: PMC2695045.
      Citations: 232     Fields:    Translation:HumansCells
    68. Coustan-Smith E, Mullighan CG, Onciu M, Behm FG, Raimondi SC, Pei D, Cheng C, Su X, Rubnitz JE, Basso G, Biondi A, Pui CH, Downing JR, Campana D. Early T-cell precursor leukaemia: a subtype of very high-risk acute lymphoblastic leukaemia. Lancet Oncol. 2009 Feb; 10(2):147-56. PMID: 19147408; PMCID: PMC2840241.
      Citations: 323     Fields:    Translation:Humans
    69. Mullighan CG, Su X, Zhang J, Radtke I, Phillips LA, Miller CB, Ma J, Liu W, Cheng C, Schulman BA, Harvey RC, Chen IM, Clifford RJ, Carroll WL, Reaman G, Bowman WP, Devidas M, Gerhard DS, Yang W, Relling MV, Shurtleff SA, Campana D, Borowitz MJ, Pui CH, Smith M, Hunger SP, Willman CL, Downing JR, Children's Oncology Group. Deletion of IKZF1 and prognosis in acute lymphoblastic leukemia. N Engl J Med. 2009 Jan 29; 360(5):470-80. PMID: 19129520; PMCID: PMC2674612.
      Citations: 524     Fields:    Translation:HumansCells
    70. Mullighan CG, Phillips LA, Su X, Ma J, Miller CB, Shurtleff SA, Downing JR. Genomic analysis of the clonal origins of relapsed acute lymphoblastic leukemia. Science. 2008 Nov 28; 322(5906):1377-80. PMID: 19039135; PMCID: PMC2746051.
      Citations: 360     Fields:    Translation:HumansCells
    71. Freeman SS, Allen SW, Ganti R, Wu J, Ma J, Su X, Neale G, Dome JS, Daw NC, Khoury JD. Copy number gains in EGFR and copy number losses in PTEN are common events in osteosarcoma tumors. Cancer. 2008 Sep 15; 113(6):1453-61. PMID: 18704985; PMCID: PMC3529469.
      Citations: 49     Fields:    Translation:Humans
    72. Neale G, Su X, Morton CL, Phelps D, Gorlick R, Lock RB, Reynolds CP, Maris JM, Friedman HS, Dome J, Khoury J, Triche TJ, Seeger RC, Gilbertson R, Khan J, Smith MA, Houghton PJ. Molecular characterization of the pediatric preclinical testing panel. Clin Cancer Res. 2008 Jul 15; 14(14):4572-83. PMID: 18628472; PMCID: PMC4209898.
      Citations: 74     Fields:    Translation:HumansAnimalsCells
    73. Finkelstein DB, Mukatira S, Mehta PK, Obenauer JC, Su X, Webster RG, Naeve CW. Persistent host markers in pandemic and H5N1 influenza viruses. J Virol. 2007 Oct; 81(19):10292-9. PMID: 17652405; PMCID: PMC2045501.
      Citations: 104     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    74. Mullighan CG, Goorha S, Radtke I, Miller CB, Coustan-Smith E, Dalton JD, Girtman K, Mathew S, Ma J, Pounds SB, Su X, Pui CH, Relling MV, Evans WE, Shurtleff SA, Downing JR. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia. Nature. 2007 Apr 12; 446(7137):758-64. PMID: 17344859.
      Citations: 738     Fields:    Translation:HumansCells
    75. Obenauer JC, Denson J, Mehta PK, Su X, Mukatira S, Finkelstein DB, Xu X, Wang J, Ma J, Fan Y, Rakestraw KM, Webster RG, Hoffmann E, Krauss S, Zheng J, Zhang Z, Naeve CW. Large-scale sequence analysis of avian influenza isolates. Science. 2006 Mar 17; 311(5767):1576-80. PMID: 16439620.
      Citations: 297     Fields:    Translation:HumansAnimalsCells
    76. Taylor MD, Poppleton H, Fuller C, Su X, Liu Y, Jensen P, Magdaleno S, Dalton J, Calabrese C, Board J, Macdonald T, Rutka J, Guha A, Gajjar A, Curran T, Gilbertson RJ. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell. 2005 Oct; 8(4):323-35. PMID: 16226707.
      Citations: 307     Fields:    Translation:HumansAnimalsCells
    77. De La Vega FM, Gordon D, Su X, Scafe C, Isaac H, Gilbert DA, Spier EG. Power and sample size calculations for genetic case/control studies using gene-centric SNP maps: application to human chromosomes 6, 21, and 22 in three populations. Hum Hered. 2005; 60(1):43-60. PMID: 16137993.
      Citations: 8     Fields:    Translation:HumansCells
    78. De La Vega FM, Isaac H, Collins A, Scafe CR, Su X, Lippert RA, Wang Y, Laig-Webster M, Koehler RT, Ziegle JS, Wogan LT, Stevens JF, Leinen KM, Olson SJ, Guegler KJ, You X, Xu LH, Hemken HG, Kalush F, Itakura M, Zheng Y, O'Brien SJ, Clark AG, Istrail S, Hunkapiller MW, Spier EG, Gilbert DA, Halld?rsson BV, de Th? G. The linkage disequilibrium maps of three human chromosomes across four populations reflect their demographic history and a common underlying recombination pattern. Genome Res. 2005 Apr; 15(4):454-62. PMID: 15781572; PMCID: PMC1074360.
      Citations: 30     Fields:    Translation:HumansCells
    79. Avi-Itzhak HI, Su X, De La Vega FM. Selection of minimum subsets of single nucleotide polymorphisms to capture haplotype block diversity. Pac Symp Biocomput. 2003; 466-77. PMID: 12603050.
      Citations: 8     Fields:    Translation:HumansCells
    80. Su X, Wallenstein S, Bishop D. Nonoverlapping clusters: approximate distribution and application to molecular biology. Biometrics. 2001 Jun; 57(2):420-6. PMID: 11414565.
      Citations: 2     Fields:    Translation:HumansCells
    81. Benson G, Su X. On the distribution of k-tuple matches for sequence homology: a constant time exact calculation of the variance. J Comput Biol. 1998; 5(1):87-100. PMID: 9541873.
      Citations: 1     Fields:    Translation:Cells
    82. TGF-β/β2-spectrin/CTCF-regulated tumor suppression in human stem cell disorder Beckwith-Wiedemann syndrome. Journal of Clinical Investigation. 126:527-542.
    83. Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability. Hepatology. 65:678-693.
    84. New approximations for the distribution of the r -scan statistic. Statistics and Probability Letters. 46:411-419.
    85. Inhibiting glutaminase in acute myeloid leukemia. Oncotarget. 7:79722-79735.
    86. Unique Transcriptomic Profile of Collecting Duct Carcinomas Relative to Upper Tract Urothelial Carcinomas and other Kidney Carcinomas. Scientific Reports. 6.
    87. Human papillomavirus drives tumor development throughout the head and neck. Journal of Clinical Oncology. 34:4132-4141.
    88. DNA methylation signature reveals cell ontogeny of renal cell carcinomas. Clinical Cancer Research. 22:6236-6246.
    89. TCGASpliceSeq a compendium of alternative mRNA splicing in cancer. Nucleic Acids Research. 44:D1018-D1022.
    90. Prevalence of actionable mutations and copy number alterations and the price of a genomic testing panel. Oncotarget. 7:71686-71695.
    91. Cancer subtypes classification using long non-coding RNA. Oncotarget. 7:54082-54093.
    92. Characterization of long non-coding RNA transcriptome in clear-cell renal cell carcinoma by next-generation deep sequencing. Molecular Oncology. 9:32-43.
    93. Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates. Nature Communications. 7.
    94. Oncogenic viruses. European Journal of Cancer. 61:61-68.
    95. Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes. Proceedings of the National Academy of Sciences of the United States of America. 112:6431-6436.
    96. Impact and challenges in assessing tumor purity by next-generation sequencing. 359-371.
    97. Genomic Characterization of Renal Cell Carcinoma with Sarcomatoid Dedifferentiation Pinpoints Recurrent Genomic Alterations. European Urology.
    98. Specific micro-RNA expression patterns distinguish the basal and luminal subtypes of muscle-invasive bladder cancer. Oncotarget. 7:80164-80174.
    99. Erratum. Cancer Cell. 9:70.
    100. Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations. Oncotarget. 6:39865-39876.
    101. Preclinical activity of combined HDAC and KDM1A inhibition in glioblastoma. Neuro-Oncology. 17:1463-1473.
    102. Mutational profiles reveal an aberrant TGF-β-CEA regulated pathway in colon adenomas. PLoS One. 11.
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