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ZHENYA TANG

TitleAssistant Professor
InstitutionMD Anderson
DepartmentHematopathology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sameeta F, Fang H, Wang W, Tang Z, Wang SA, Toruner GA, Parisi X, Khoury JD, Issa G, Garcia-Manero G, Medeiros LJ, Tang G, Loghavi S. Myeloid neoplasm with <10% blasts and t(3;5)(q25.1;q34)/NPM::MLF1: A classification dilemma. Am J Hematol. 2024 Mar 05. PMID: 38440855.
      Citations:    Fields:    
    2. Vanjari N, Tang G, Toruner GA, Wang W, Thakral B, Zhao M, Dave BJ, Khoury JD, Medeiros LJ, Tang Z. Optical Genome Mapping Helps to Identify BCR::JAK2 Rearrangement Arising from Cryptic Complex Chromosomal Aberrations: A Case Report and Literature Review. Genes (Basel). 2023 Dec 08; 14(12). PMID: 38137010; PMCID: PMC10742890.
      Citations:    Fields:    Translation:Humans
    3. Tang G, Wu Y, Lin P, Toruner GA, Hu S, Li S, Qazilbash MH, Orlowski RZ, Ye C, Xu J, Nahmod KA, Medeiros LJ, Tang Z. Cytogenetic Profile in Monoclonal Gammopathy of Undetermined Significance, Smoldering and Symptomatic Multiple Myeloma: A Study of 1087 Patients with Highly Purified Plasma Cells. Cancers (Basel). 2023 Dec 02; 15(23). PMID: 38067393; PMCID: PMC10705751.
      Citations:    
    4. Esplen HP, Yang RK, Kalia A, Tang Z, Tang G, Medeiros LJ, Toruner GA. Recurrent Somatic Copy Number Alterations and Their Association with Oncogene Expression Levels in High-Grade Ovarian Serous Carcinoma. Life (Basel). 2023 Nov 10; 13(11). PMID: 38004332; PMCID: PMC10672014.
      Citations: 1     
    5. Diks J, Tang Z, Altan M, Anderson S, Chen H, Rashid A, Yang RK, Routbort MJ, Patel KP, Toruner GA, Medeiros LJ, Tang G, Luthra R, Roy-Chowdhuri S. Detection of clinically actionable gene fusions by next-generation sequencing-based RNA sequencing of non-small cell lung cancer cytology specimens: A single-center experience with comparison to fluorescence in?situ hybridization. Cancer Cytopathol. 2024 Jan; 132(1):41-49. PMID: 37747438.
      Citations:    Fields:    Translation:Humans
    6. Fang H, Beird HC, Wang SA, Ibrahim AF, Tang Z, Tang G, You MJ, Hu S, Xu J, Li S, Yin CC, El Hussein S, Le N, Futreal PA, Bueso-Ramos C, Thakral B, Kadia TM, Thornton R, Little L, Gumbs C, Song X, Medeiros LJ, Wang W. T-prolymphocytic leukemia: TCL1 or MTCP1 rearrangement is not mandatory to establish diagnosis. Leukemia. 2023 09; 37(9):1919-1921. PMID: 37443196.
      Citations:    Fields:    Translation:Humans
    7. Qiu L, Tang G, Li S, Vega F, Lin P, Wang SA, Wang W, Iyer SP, Malpica L, Miranda RN, Konoplev S, Tang Z, Fang H, Medeiros LJ, Xu J. DUSP22 rearrangement is associated with a distinctive immunophenotype but not outcome in patients with systemic ALK-negative anaplastic large cell lymphoma. Haematologica. 2023 06 01; 108(6):1604-1615. PMID: 36453104; PMCID: PMC10230410.
      Citations: 2     Fields:    Translation:Humans
    8. Li N, Lin P, Zuo Z, You MJ, Shuai W, Orlowski R, Manasanch EE, Li S, Xu J, Garces S, Jelloul FZ, Tang Z, Wang W, Medeiros LJ, Yin CC. Plasma cell myeloma with RAS/BRAF mutations is frequently associated with a complex karyotype, advanced stage disease, and poorer prognosis. Cancer Med. 2023 07; 12(13):14293-14304. PMID: 37212518; PMCID: PMC10358222.
      Citations: 1     Fields:    Translation:Humans
    9. Jelloul FZ, Routbort MJ, DiNardo CD, Bueso-Ramos CE, Kanagal-Shamanna R, Thakral B, Zuo Z, Yin CC, Loghavi S, Ok CY, Wang SA, Tang Z, You MJ, Patel KP, Medeiros LJ, Quesada AE. DDX41 mutations in patients with non-myeloid hematologic neoplasms. Am J Hematol. 2023 08; 98(8):E193-E196. PMID: 37154083.
      Citations:    Fields:    Translation:Humans
    10. Hu Z, Medeiros LJ, Xu M, Yuan J, Peker D, Tang Z, Mai B, Thakral B, Rios A, Hu S, Wang W, Shao L. T-Cell Prolymphocytic Leukemia With t(X;14)(q28;q11.2): A Clinicopathologic Study of 15 Cases. Am J Clin Pathol. 2023 04 04; 159(4):325-336. PMID: 36883805.
      Citations:    Fields:    Translation:HumansCells
    11. El Hussein S, Medeiros LJ, Gruschkus SK, Wei P, Schlette E, Fang H, Jelloul FZ, Wang W, Fiskus W, Kanagal-Shamanna R, Loghavi S, Yang H, Li S, Xu J, Tang Z, Thakral B, Jain N, Wierda WG, Patel K, Bhalla KN, Khoury JD. Immune evasion phenotype is common in Richter transformation diffuse large B-cell lymphoma?variant. Virchows Arch. 2023 Jun; 482(6):1011-1019. PMID: 36864257.
      Citations:    Fields:    Translation:HumansCells
    12. El Hussein S, Medeiros LJ, Lyapichev KA, Fang H, Jelloul FZ, Fiskus W, Chen J, Wei P, Schlette E, Xu J, Li S, Kanagal-Shamanna R, Yang H, Tang Z, Thakral B, Loghavi S, Jain N, Thompson PA, Ferrajoli A, Wierda WG, Jabbour E, Patel KP, Dabaja BS, Bhalla KN, Khoury JD. Immunophenotypic and genomic landscape of Richter transformation diffuse large B-cell lymphoma. Pathology. 2023 Jun; 55(4):514-524. PMID: 36933995.
      Citations:    Fields:    Translation:Humans
    13. Wang M, Ding Q, Gu J, Sfamenos SM, Huo L, Tang Z, Sun H, Robinson M, Tang G, Lim B, Wu Y, Albarracin CT, Sahin AA, Chen H. Breast Cancer With a HER2 FISH Group 2 Result: Should HER2 Tests be Repeated? Clin Breast Cancer. 2023 06; 23(4):415-422. PMID: 36878823.
      Citations:    Fields:    Translation:Humans
    14. Tang Z, Wang W, Yang S, El Achi H, Fang H, Nahmod KA, Toruner GA, Xu J, Thakral B, Ayoub E, Issa GC, Yin CC, You MJ, Miranda RN, Khoury JD, Medeiros LJ, Tang G. 3q26.2/MECOM Rearrangements by Pericentric Inv(3): Diagnostic Challenges and Clinicopathologic Features. Cancers (Basel). 2023 Jan 11; 15(2). PMID: 36672407; PMCID: PMC9856433.
      Citations:    
    15. Xu J, Li S, Yin CC, Patel KP, Tang G, Wang W, Miranda RN, Garces S, Tang Z, Lin P, Medeiros LJ. Classic Hodgkin lymphoma with marked granulomatous reaction: A clinicopathologic study of 20 cases. Hum Pathol. 2023 04; 134:114-123. PMID: 36584716.
      Citations:    Fields:    Translation:HumansCells
    16. Tang G, Li S, Toruner GA, Jain P, Tang Z, Hu S, Xu J, Cheng J, Robinson M, Vega F, Medeiros LJ. Clinical impact of 5'MYC or 3'MYC gain/loss detected by FISH in patients with aggressive B-cell lymphomas. Cancer Genet. 2023 04; 272-273:1-8. PMID: 36566629.
      Citations:    Fields:    Translation:Humans
    17. Gu J, Tang Z. Status and Prospects of Fluorescence In Situ Hybridization Automation-A Survey among Laboratory Directors and Their Designates. Genes (Basel). 2022 Nov 11; 13(11). PMID: 36421773; PMCID: PMC9690641.
      Citations: 1     Fields:    
    18. Ye MT, Wang Y, Zuo Z, Calin S, He H, Tang Z, Jabbour EJ, Borthakur G, Zhang Y, Yang Y, You MJ. Integrated clinical genotype-phenotype characteristics of early T-cell precursor acute lymphoblastic leukemia. Cancer. 2023 01 01; 129(1):49-59. PMID: 36281717.
      Citations:    Fields:    Translation:HumansCells
    19. Fang H, Wang SA, You MJ, Hu S, Miranda RN, Tang Z, Lin P, Jorgensen JL, Xu J, Thakral B, Schlette EJ, El Hussein S, Bueso-Ramos C, Medeiros LJ, Wang W. Flow cytometry immunophenotypic features of pure erythroid leukemia and the distinction from reactive erythroid precursors. Cytometry B Clin Cytom. 2022 11; 102(6):440-447. PMID: 36156384.
      Citations:    Fields:    Translation:Humans
    20. Nahmod KA, Wang W, Saluja K, Tang Z, Medeiros LJ, Thakral B. B-lymphoblastic leukemia with Burkitt-like morphology and aberrant myeloperoxidase expression: A diagnostic conundrum. EJHaem. 2022 Nov; 3(4):1406-1408. PMID: 36467827; PMCID: PMC9713052.
      Citations:    
    21. Fang H, Wang SA, Khoury JD, El Hussein S, Kim DH, Tashakori M, Tang Z, Li S, Hu Z, Jelloul FZ, Patel KP, McDonnell TJ, Kadia T, Medeiros LJ, Wang W. Pure erythroid leukemia is characterized by biallelic TP53 inactivation and abnormal p53 expression patterns in de novo and secondary cases. Haematologica. 2022 09 01; 107(9):2232-2237. PMID: 35511670; PMCID: PMC9425316.
      Citations:    Fields:    
    22. Wang L, Wang W, Beird HC, Cheng X, Fang H, Tang G, Toruner GA, Yin CC, You MJ, Issa GC, Borthakur G, Peng G, Khoury JD, Medeiros LJ, Tang Z. PPP1R7 Is a Novel Translocation Partner of CBFB via t(2;16)(q37;q22) in Acute Myeloid Leukemia. Genes (Basel). 2022 07 29; 13(8). PMID: 36011278; PMCID: PMC9407081.
      Citations:    
    23. Wang W, Xu J, Khoury JD, Pemmaraju N, Fang H, Miranda RN, Yin CC, Hussein SE, Jia F, Tang Z, Hu S, Konopleva M, Medeiros LJ, Wang SA. Immunophenotypic and Molecular Features of Acute Myeloid Leukemia with Plasmacytoid Dendritic Cell Differentiation Are Distinct from Blastic Plasmacytoid Dendritic Cell Neoplasm. Cancers (Basel). 2022 Jul 11; 14(14). PMID: 35884435; PMCID: PMC9324882.
      Citations:    
    24. Tashakori M, Kadia T, Loghavi S, Daver N, Kanagal-Shamanna R, Pierce S, Sui D, Wei P, Khodakarami F, Tang Z, Routbort M, Bivins CA, Jabbour EJ, Medeiros LJ, Bhalla K, Kantarjian HM, Ravandi F, Khoury JD. TP53 copy number and protein expression inform mutation status across risk categories in acute myeloid leukemia. Blood. 2022 07 07; 140(1):58-72. PMID: 35390143; PMCID: PMC9346958.
      Citations: 1     Fields:    Translation:Humans
    25. Fang H, Khoury JD, Torres-Cabala CA, Ng SB, Xu J, El Hussein S, Hu S, Vega F, Li S, Tang Z, Tang G, Medeiros LJ, Wang W. Expression pattern and diagnostic utility of BCL11B in mature T- and NK-cell neoplasms. Pathology. 2022 Dec; 54(7):893-899. PMID: 35864006.
      Citations:    Fields:    
    26. Fang H, Wang SA, Hu S, Konoplev SN, Mo H, Liu W, Zuo Z, Xu J, Jorgensen JL, Yin CC, El Hussein S, Jelloul FZ, Tang Z, Medeiros LJ, Wang W. Acute promyelocytic leukemia: Immunophenotype and differential diagnosis by flow cytometry. Cytometry B Clin Cytom. 2022 07; 102(4):283-291. PMID: 35716019.
      Citations:    Fields:    Translation:Humans
    27. Wang X, Tang G, Hu Z, Fang H, Wang W, Tang Z, Toruner GA, Zhou T, DiNardo CD, Garcia-Manero G, Verstovsek S, Bueso-Ramos CE, Medeiros LJ, Hu S. Myeloid neoplasms with 8q24/MYC rearrangement are frequently associated with myelodysplasia, complex karyotype, TP53 alterations, and inferior survival. Br J Haematol. 2022 08; 198(3):604-608. PMID: 35645146.
      Citations:    Fields:    Translation:Humans
    28. Yin W, Guo M, Tang Z, Toruner GA, Cheng J, Medeiros LJ, Tang G. MET Expression Level in Lung Adenocarcinoma Loosely Correlates with MET Copy Number Gain/Amplification and Is a Poor Predictor of Patient Outcome. Cancers (Basel). 2022 May 14; 14(10). PMID: 35626038; PMCID: PMC9139916.
      Citations:    
    29. Fang H, Toruner GA, Tang Z, Tang G, Weissferdt A, Tashakori M, El Hussein S, Thakral B, Quesada AE, Wang W, Patel KP, Garcia-Manero G, Medeiros LJ, Bueso-Ramos CE, Jelloul FZ. Primary mediastinal germ cell tumor and clonally related and unique hematologic neoplasms with i(12p) and TP53 mutation: A report of two cases. Ann Diagn Pathol. 2022 Aug; 59:151951. PMID: 35489185.
      Citations:    Fields:    Translation:HumansCells
    30. Qiu L, Wang SA, Vega F, Khoury JD, Tang Z, Garces S, Medeiros LJ, Thakral B. From the archives of MD Anderson Cancer Center: Intravascular large B-cell lymphoma with numerous circulating lymphoma cells. Ann Diagn Pathol. 2022 Jun; 58:151934. PMID: 35299081.
      Citations:    Fields:    Translation:HumansCells
    31. Tang G, Zou Y, Wang SA, Borthakur G, Toruner G, Hu S, Li S, Xu J, Medeiros LJ, Tang Z. 3'CBFB deletion in CBFB-rearranged acute myeloid leukemia retains morphological features associated with inv(16), but patients have higher risk of relapse and may require stem cell transplant. Ann Hematol. 2022 Apr; 101(4):847-854. PMID: 35184217.
      Citations:    Fields:    Translation:HumansCells
    32. Zhao M, Medeiros LJ, Wang W, Tang G, Jung HS, Sfamenos SM, Fang H, Toruner GA, Hu S, Yin CC, Lin P, Gu J, Peng G, You MJ, Khoury JD, Wang SA, Tang Z. Newly designed breakapart FISH probe helps to identify cases with true MECOM rearrangement in myeloid malignancies. Cancer Genet. 2022 04; 262-263:23-29. PMID: 34974290.
      Citations:    Fields:    Translation:Humans
    33. Yin CC, Pemmaraju N, You MJ, Li S, Xu J, Wang W, Tang Z, Alswailmi O, Bhalla KN, Qazilbash MH, Konopleva M, Khoury JD. Integrated Clinical Genotype-Phenotype Characteristics of Blastic Plasmacytoid Dendritic Cell Neoplasm. Cancers (Basel). 2021 Nov 23; 13(23). PMID: 34884997; PMCID: PMC8656770.
      Citations: 2     
    34. Yang RK, Toruner GA, Wang W, Fang H, Issa GC, Wang L, Thakral B, Patel KP, Peng G, Liu S, Yin CC, Borthakur G, Tang Z, Wang SA, Miranda RN, Khoury JD, Medeiros LJ, Tang G, Quesada AE. CBFB Break-Apart FISH Testing: An Analysis of 1629 AML Cases with a Focus on Atypical Findings and Their Implications in Clinical Diagnosis and Management. Cancers (Basel). 2021 Oct 26; 13(21). PMID: 34771519; PMCID: PMC8582369.
      Citations:    
    35. Toruner GA, Thakral B, Tang Z, Tang G, Medeiros LJ, Oran B. Clonal cytogenetic abnormalities in donor-derived cells after sex mismatched allogeneic stem cell transplantation. Cancer Genet. 2021 11; 258-259:120-130. PMID: 34715428.
      Citations:    Fields:    Translation:Humans
    36. Issa GC, Zarka J, Sasaki K, Qiao W, Pak D, Ning J, Short NJ, Haddad F, Tang Z, Patel KP, Cuglievan B, Daver N, DiNardo CD, Jabbour E, Kadia T, Borthakur G, Garcia-Manero G, Konopleva M, Andreeff M, Kantarjian HM, Ravandi F. Predictors of outcomes in adults with acute myeloid leukemia and KMT2A rearrangements. Blood Cancer J. 2021 09 29; 11(9):162. PMID: 34588432; PMCID: PMC8481264.
      Citations: 2     Fields:    Translation:Humans
    37. Tang Z, Kanagal-Shamanna R, Tang G, Patel K, Medeiros LJ, Toruner GA. Analytical and clinical performance of chromosomal microarrays compared with FISH panel and conventional karyotyping in patients with chronic lymphocytic leukemia. Leuk Res. 2021 09; 108:106616. PMID: 34022744.
      Citations:    Fields:    Translation:HumansCells
    38. Yin W, Cheng J, Tang Z, Toruner G, Hu S, Guo M, Robinson M, Medeiros LJ, Tang G. MET Amplification (MET/CEP7 Ratio?= 1.8) Is an Independent Poor Prognostic Marker in Patients With Treatment-naive Non-Small-cell Lung Cancer. Clin Lung Cancer. 2021 07; 22(4):e512-e518. PMID: 33288441.
      Citations: 2     Fields:    Translation:Humans
    39. Yin W, Liu W, Guo M, Tang Z, Toruner G, Robinson M, Cheng J, Hu S, Medeiros LJ, Tang G. Acquired MET amplification in non-small cell lung cancer is highly associated with the exposure of EGFR inhibitors and may not affect patients' outcome. Exp Mol Pathol. 2021 02; 118:104572. PMID: 33189723.
      Citations: 1     Fields:    Translation:Humans
    40. Ramani NS, Chen H, Broaddus RR, Lazar AJ, Luthra R, Medeiros LJ, Patel KP, Rashid A, Routbort MJ, Stewart J, Tang Z, Bassett R, Manekia J, Barkoh BA, Dang H, Roy-Chowdhuri S. Utilization of cytology smears improves success rates of RNA-based next-generation sequencing gene fusion assays for clinically relevant predictive biomarkers. Cancer Cytopathol. 2021 05; 129(5):374-382. PMID: 33119213.
      Citations: 2     Fields:    Translation:Humans
    41. Ronaghy A, Hu S, Tang Z, Wang W, Tang G, Loghavi S, Li S, Thakral B, Medeiros LJ, Muzzafar T. Myeloid neoplasms associated with t(3;12)(q26.2;p13) are clinically aggressive, show myelodysplasia, and frequently harbor chromosome 7 abnormalities. Mod Pathol. 2021 02; 34(2):300-313. PMID: 33110238.
      Citations: 1     Fields:    Translation:HumansCells
    42. Fang H, Medeiros LJ, Tang Z, Wang W, Ok CY, Patel KP, Khoury JD, Thakral B. From the archives of MD Anderson Cancer Center: Untreated leukemic non-nodal mantle cell lymphoma with relapse as pleomorphic variant mantle cell lymphoma 21 years later. Ann Diagn Pathol. 2021 Feb; 50:151649. PMID: 33189964.
      Citations:    Fields:    Translation:Humans
    43. Tang Z, Toruner GA, Tang G, Yin CC, Wang W, Hu S, Thakral B, Wang SA, Miranda RN, Khoury JD, Medeiros LJ. Correction: Chronic myeloid leukemia with insertion-derived BCR-ABL1 fusion: redefining complex chromosomal abnormalities by correlation of FISH and karyotype predicts prognosis. Mod Pathol. 2020 Oct; 33(10):2088. PMID: 32737448.
      Citations:    Fields:    
    44. Shuai W, Lin P, Strati P, Patel KP, Routbort MJ, Hu S, Wei P, Khoury JD, You MJ, Loghavi S, Tang Z, Fang H, Thakral B, Medeiros LJ, Wang W. Clinicopathological characterization of chronic lymphocytic leukemia with MYD88 mutations: L265P and non-L265P mutations are associated with different features. Blood Cancer J. 2020 08 26; 10(8):86. PMID: 32848129; PMCID: PMC7450076.
      Citations: 2     Fields:    Translation:Humans
    45. Liu W, Burger JA, Xu J, Tang Z, Toruner G, Khanlari M, Medeiros LJ, Tang G. LPL deletion is associated with poorer response to ibrutinib-based treatments and overall survival in TP53-deleted chronic lymphocytic leukemia. Ann Hematol. 2020 Oct; 99(10):2343-2349. PMID: 32833105.
      Citations:    Fields:    Translation:Humans
    46. Chen Z, Hu S, Wang SA, Konopleva M, Tang Z, Xu J, Li S, Toruner G, Thakral B, Medeiros LJ, Tang G. Chronic myeloid leukemia presenting in lymphoblastic crisis, a differential diagnosis with Philadelphia-positive B-lymphoblastic leukemia. Leuk Lymphoma. 2020 12; 61(12):2831-2838. PMID: 32700989.
      Citations: 2     Fields:    Translation:HumansCells
    47. Thakral B, Daver N, Tang Z, Patel KP, Ok CY, Loghavi S, Khoury JD, Alotaibi AS, Konopleva M, Yilmaz M, Medeiros LJ. Clonal evolution with acquisition of BCR-ABL1 in refractory acute myeloid leukemia post therapy with FLT3-inhibitor. Leuk Lymphoma. 2020 12; 61(13):3243-3246. PMID: 32696696.
      Citations:    Fields:    Translation:Humans
    48. Tang Z, Chen H, Hong L, Tang G, Toruner GA, Wang W, Roy Chowdhuri S, Yin W, Jung HS, Gu J, Routbort MJ, Zhang J, Khoury JD, Medeiros LJ. Inconsistent Intersample ALK FISH Results in Patients with Lung Cancer: Analysis of Potential Causes. Cancers (Basel). 2020 Jul 14; 12(7). PMID: 32674491; PMCID: PMC7409019.
      Citations:    
    49. Tang Z, Toruner GA, Tang G, Cameron Yin C, Wang W, Hu S, Thakral B, Wang SA, Miranda RN, Khoury JD, Medeiros LJ. Chronic myeloid leukemia with insertion-derived BCR-ABL1 fusion: redefining complex chromosomal abnormalities by correlation of FISH and karyotype predicts prognosis. Mod Pathol. 2020 10; 33(10):2035-2045. PMID: 32404952.
      Citations: 1     Fields:    Translation:Humans
    50. Wang W, Beird H, Kroll CJ, Hu S, Bueso-Ramos CE, Fang H, Tang G, Tang Z, Wang F, Takahashi K, You MJ, Khoury JD, Medeiros LJ, Futreal PA. T(6;14)(q25;q32) involves BCL11B and is highly associated with mixed-phenotype acute leukemia, T/myeloid. Leukemia. 2020 09; 34(9):2509-2512. PMID: 32099038.
      Citations: 5     Fields:    Translation:HumansCells
    51. Xie W, Xu J, Hu S, Li S, Wang W, Cameron Yin C, Toruner G, Tang Z, Medeiros LJ, Tang G. iAMP21 in acute myeloid leukemia is associated with complex karyotype, TP53 mutation and dismal outcome. Mod Pathol. 2020 07; 33(7):1389-1397. PMID: 32034282.
      Citations: 1     Fields:    Translation:HumansCells
    52. Toruner GA, Tang Z, Tang G, Medeiros LJ, Hu S. Low ALK FISH positive metastatic non-small cell lung cancer (NSCLC) patients have shorter progression-free survival after treatment with ALK inhibitors. Cancer Genet. 2020 02; 241:57-60. PMID: 31870845.
      Citations: 1     Fields:    Translation:Humans
    53. Tang Z, Wang L, Tang G, Medeiros LJ. Fluorescence in Situ Hybridization (FISH) for Detecting Anaplastic Lymphoma Kinase (ALK) Rearrangement in Lung Cancer: Clinically Relevant Technical Aspects. Int J Mol Sci. 2019 Aug 13; 20(16). PMID: 31412611; PMCID: PMC6720438.
      Citations: 7     Fields:    Translation:Humans
    54. Sakhdari A, Tang Z, Ok CY, Bueso-Ramos CE, Medeiros LJ, Huh YO. Homogeneously staining region (hsr) on chromosome 11 is highly specific for KMT2A amplification in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Cancer Genet. 2019 10; 238:18-22. PMID: 31425921.
      Citations: 5     Fields:    Translation:HumansCells
    55. Jain P, Gu J, Kanagal-Shamanna R, Tang Z, Patel KP, Yao H, Fang L, Bao HY, Liu CH, Lin P, Medeiros LJ, Lu X. Clinical implications of cytogenetic heterogeneity in Philadelphia chromosome positive (Ph+) adult B cell acute lymphoblastic leukemia following tyrosine kinase inhibitors and chemotherapy regimens. Leuk Res. 2019 09; 84:106176. PMID: 31279181.
      Citations: 2     Fields:    Translation:HumansCells
    56. Chen Z, Sun Y, Xie W, Wang SA, Hu S, Li S, Tang Z, Toruner G, Medeiros LJ, Tang G. Is hyperdiploidy a favorable cytogenetics in adults with B-lymphoblastic leukemia? Cancer Med. 2019 08; 8(9):4093-4099. PMID: 31173486; PMCID: PMC6675728.
      Citations: 3     Fields:    Translation:Humans
    57. Tang Z, Tang G, Hu S, Patel KP, Cameron Yin C, Wang W, Lin P, Toruner GA, Ok CY, Gu J, Lu X, Khoury JD, Jeffrey Medeiros L. Data on MECOM rearrangement-driven chromosomal aberrations in myeloid malignancies. Data Brief. 2019 Jun; 24:104025. PMID: 31193989; PMCID: PMC6545385.
      Citations:    
    58. Aung PP, Sukswai N, Nejati R, Loghavi S, Chen W, Torres-Cabala CA, Yin CC, Konopleva M, Zheng X, Wang J, Tang Z, Medeiros LJ, Prieto VG, Pemmaraju N, Khoury JD. PD1/PD-L1 Expression in Blastic Plasmacytoid Dendritic Cell Neoplasm. Cancers (Basel). 2019 May 19; 11(5). PMID: 31109153; PMCID: PMC6562447.
      Citations: 1     
    59. Routbort MJ, DiNardo CD, Bueso-Ramos CE, Kanagal-Shamanna R, Khoury JD, Thakral B, Zuo Z, Yin CC, Loghavi S, Ok CY, Wang SA, Tang Z, Bannon SA, Benton CB, Garcia-Manero G, Kantarjian H, Luthra R, Medeiros LJ, Patel KP, Quesada AE. DDX41 mutations in myeloid neoplasms are associated with male gender, TP53 mutations and high-risk disease. Am J Hematol. 2019 07; 94(7):757-766. PMID: 30963592.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    60. Tang Z, Tang G, Hu S, Patel KP, Yin CC, Wang W, Lin P, Toruner GA, Ok CY, Gu J, Lu X, Khoury JD, Medeiros LJ. Deciphering the complexities of MECOM rearrangement-driven chromosomal aberrations. Cancer Genet. 2019 04; 233-234:21-31. PMID: 31109591.
      Citations: 4     Fields:    Translation:Humans
    61. Tang G, Hu S, Wang SA, Xie W, Lin P, Xu J, Toruner G, Zhao M, Gu J, Doty M, Li S, Medeiros LJ, Tang Z. t(3;8)(q26.2;q24) Often Leads to MECOM/MYC Rearrangement and Is Commonly Associated with Therapy-Related Myeloid Neoplasms and/or Disease Progression. J Mol Diagn. 2019 03; 21(2):343-351. PMID: 30576868.
      Citations: 4     Fields:    Translation:Humans
    62. Tang Z, Li Y, Wang W, Yin CC, Tang G, Aung PP, Hu S, Lu X, Toruner GA, Medeiros LJ, Khoury JD. Genomic aberrations involving 12p/ETV6 are highly prevalent in blastic plasmacytoid dendritic cell neoplasms and might represent early clonal events. Leuk Res. 2018 10; 73:86-94. PMID: 30248580.
      Citations: 11     Fields:    Translation:HumansCellsCTClinical Trials
    63. Wang W, Routbort MJ, Loghavi S, Tang Z, Medeiros LJ, Wang SA. Characterization of chronic myelomonocytic leukemia with TP53 mutations. Leuk Res. 2018 07; 70:97-99. PMID: 29908419.
      Citations: 4     Fields:    Translation:Humans
    64. Tang Z, Zhang J, Chen H, Lu S, Cheng J, Tang G, Medeiros LJ. Reply to Lambros et al. Mod Pathol. 2018 03; 31(3):541-542. PMID: 29515243.
      Citations:    Fields:    Translation:Humans
    65. Fang L, Chen H, Tang Z, Kalhor N, Liu CH, Yao H, Hu S, Lin P, Zhao J, Luthra R, Singh RR, Routbort MJ, Hong D, Medeiros LJ, Lu X. MET amplification assessed using optimized FISH reporting criteria predicts early distant metastasis in patients with non-small cell lung cancer. Oncotarget. 2018 Feb 27; 9(16):12959-12970. PMID: 29560123; PMCID: PMC5849187.
      Citations: 4     Fields:    
    66. Boddu PC, Wang SA, Pemmaraju N, Tang Z, Hu S, Li S, Xu J, Medeiros LJ, Tang G. 8q24/MYC rearrangement is a recurrent cytogenetic abnormality in blastic plasmacytoid dendritic cell neoplasms. Leuk Res. 2018 03; 66:73-78. PMID: 29407586.
      Citations: 7     Fields:    Translation:HumansCells
    67. Carballo-Zarate A, Verstovsek S, Wang SA, Hu S, Li S, Xu J, Zuo W, Tang Z, Yin CC, Medeiros LJ, Bueso-Ramos CE, Tang G, Hidalgo L?pez JE. Bone marrow findings in blast phase of polycythemia vera. Ann Hematol. 2018 Mar; 97(3):425-434. PMID: 29285580.
      Citations: 5     Fields:    Translation:Humans
    68. Hu Z, Hu S, Ji C, Tang Z, Thakral B, Loghavi S, Medeiros LJ, Wang W. 3q26/EVI1 rearrangement in myelodysplastic/myeloproliferative neoplasms: An early event associated with a poor prognosis. Leuk Res. 2018 02; 65:25-28. PMID: 29288910.
      Citations: 2     Fields:    Translation:HumansCells
    69. Wang W, Routbort MJ, Tang Z, Ok CY, Patel KP, Daver N, Garcia-Manero G, Medeiros LJ, Wang SA. Characterization of TP53 mutations in low-grade myelodysplastic syndromes and myelodysplastic syndromes with a non-complex karyotype. Eur J Haematol. 2017 Dec; 99(6):536-543. PMID: 28926144.
      Citations: 12     Fields:    Translation:Humans
    70. Tang Z, Zhang J, Lu X, Wang W, Chen H, Robinson MK, Cheng J, Tang G, Medeiros LJ. Coexistent genetic alterations involving ALK, RET, ROS1 or MET in 15 cases of lung adenocarcinoma. Mod Pathol. 2018 02; 31(2):307-312. PMID: 28914263.
      Citations: 15     Fields:    Translation:Humans
    71. El Naofal M, Kim A, Yon HY, Baity M, Ming Z, Bui-Griffith J, Tang Z, Robinson M, Grubbs EG, Cote GJ, Hu P. Role of CDKN2C Fluorescence In Situ Hybridization in the Management of Medullary Thyroid Carcinoma. Ann Clin Lab Sci. 2017 Sep; 47(5):523-528. PMID: 29066476; PMCID: PMC7057027.
      Citations: 2     Fields:    Translation:HumansCells
    72. Gong Z, Zheng L, Tang Z, Chen Z, Wang W, Bai S, Tang G, Medeiros LJ, Hu S. Erratum to: Role of complexity of variant Philadelphia chromosome in chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Ann Hematol. 2017 07; 96(7):1239. PMID: 28526956.
      Citations: 1     Fields:    
    73. Tang G, Hidalgo Lopez JE, Wang SA, Hu S, Ma J, Pierce S, Zuo W, Carballo-Zarate AA, Yin CC, Tang Z, Li S, Medeiros LJ, Verstovsek S, Bueso-Ramos CE. Characteristics and clinical significance of cytogenetic abnormalities in polycythemia vera. Haematologica. 2017 09; 102(9):1511-1518. PMID: 28473622; PMCID: PMC5685217.
      Citations: 14     Fields:    Translation:HumansCells
    74. Hu Z, Medeiros LJ, Fang L, Sun Y, Tang Z, Tang G, Sun T, Quesada AE, Hu S, Wang SA, Pei L, Lu X. Prognostic significance of cytogenetic abnormalities in T-cell prolymphocytic leukemia. Am J Hematol. 2017 May; 92(5):441-447. PMID: 28194886.
      Citations: 6     Fields:    Translation:Humans
    75. Gur HD, Wang SA, Tang Z, Hu S, Li S, Medeiros LJ, Tang G. Clinical significance of isolated del(7p) in myeloid neoplasms. Leuk Res. 2017 04; 55:18-22. PMID: 28119224.
      Citations: 1     Fields:    Translation:HumansCells
    76. Gong Z, Zheng L, Tang Z, Chen Z, Wang W, Bai S, Tang G, Hu S. Role of complexity of variant Philadelphia chromosome in chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Ann Hematol. 2017 03; 96(3):501-504. PMID: 27915425.
      Citations: 4     Fields:    Translation:HumansCells
    77. Tang Z, Medeiros LJ, Yin CC, Wang W, Lu X, Young KH, Khoury JD, Tang G. Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms: a diagnostic dilemma for clinical cytogeneticists. Mol Cytogenet. 2016; 9:62. PMID: 27508005; PMCID: PMC4977628.
      Citations: 4     
    78. Tang Z, Li Y, Wang SA, Hu S, Li S, Lu X, Khoury JD, Medeiros LJ, Tang G. Clinical significance of acquired loss of the X chromosome in bone marrow. Leuk Res. 2016 08; 47:109-13. PMID: 27299973.
      Citations: 2     Fields:    Translation:HumansCells
    79. Goswami RS, Wang SA, DiNardo C, Tang Z, Li Y, Zuo W, Hu S, Li S, Medeiros LJ, Tang G. Newly emerged isolated Del(7q) in patients with prior cytotoxic therapies may not always be associated with therapy-related myeloid neoplasms. Mod Pathol. 2016 07; 29(7):727-34. PMID: 27056073.
      Citations: 4     Fields:    Translation:HumansCells
    80. Tang Z, Tang G, Wang SA, Lu X, Young KH, Bueso-Ramos CE, Alvarado Y, Medeiros LJ, Khoury JD. Simultaneous deletion of 3'ETV6 and 5'EWSR1 genes in blastic plasmacytoid dendritic cell neoplasm: case report and literature review. Mol Cytogenet. 2016; 9:23. PMID: 26925167; PMCID: PMC4769509.
      Citations: 6     
    81. Li Y, Hu S, Wang SA, Li S, Huh YO, Tang Z, Medeiros LJ, Tang G. The clinical significance of 8q24/MYC rearrangement in chronic lymphocytic leukemia. Mod Pathol. 2016 05; 29(5):444-51. PMID: 26916070.
      Citations: 7     Fields:    Translation:Humans
    82. Wang W, Ali S, Tang Z, Miranda RN, Yang S, Medeiros LJ, Hu S. Constitutional pericentric inversion of chromosome 9 has no impact on survival in chronic myelogenous leukemia. Ann Hematol. 2016 Mar; 95(4):657-9. PMID: 26758271.
      Citations: 2     Fields:    Translation:HumansCells
    83. Gu J, Patel KP, Bai B, Liu CH, Tang G, Kantarjian HM, Tang Z, Abraham R, Luthra R, Medeiros LJ, Lin P, Lu X. Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression. Mol Cytogenet. 2015; 8:68. PMID: 26300976; PMCID: PMC4545786.
      Citations: 1     
    84. Tang G, Fu B, Hu S, Lu X, Tang Z, Li S, Jabbar K, Khoury JD, Medeiros LJ, Wang SA. Prognostic impact of acquisition of cytogenetic abnormalities during the course of chronic myelomonocytic leukemia. Am J Hematol. 2015 Oct; 90(10):882-7. PMID: 26148174.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    85. Subbiah V, Berry J, Roxas M, Guha-Thakurta N, Subbiah IM, Ali SM, McMahon C, Miller V, Cascone T, Pai S, Tang Z, Heymach JV. Systemic and CNS activity of the RET inhibitor vandetanib combined with the mTOR inhibitor everolimus in KIF5B-RET re-arranged non-small cell lung cancer with brain metastases. Lung Cancer. 2015 Jul; 89(1):76-9. PMID: 25982012; PMCID: PMC4998046.
      Citations: 31     Fields:    Translation:Humans
    86. Cui W, Hu SX, Tang ZY, Hu KQ. In-vivo effects and mechanisms of celecoxib-reduced growth of cyclooxygenase-2 (COX-2)-expressing versus COX-2-deleted human HCC xenografts in nude mice. Anticancer Drugs. 2008 Oct; 19(9):891-7. PMID: 18766003.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    87. Tang ZY, Loss G, Carmody I, Cohen AJ. TIMP-3 ameliorates hepatic ischemia/reperfusion injury through inhibition of tumor necrosis factor-alpha-converting enzyme activity in rats. Transplantation. 2006 Dec 15; 82(11):1518-23. PMID: 17164725.
      Citations: 16     Fields:    Translation:HumansAnimals
    88. Prakash O, Swamy OR, Peng X, Tang ZY, Li L, Larson JE, Cohen JC, Gill J, Farr G, Wang S, Samaniego F. Activation of Src kinase Lyn by the Kaposi sarcoma-associated herpesvirus K1 protein: implications for lymphomagenesis. Blood. 2005 May 15; 105(10):3987-94. PMID: 15665117; PMCID: PMC1895082.
      Citations: 41     Fields:    Translation:AnimalsCells
    89. Prakash O, Tang ZY, Peng X, Coleman R, Gill J, Farr G, Samaniego F. Tumorigenesis and aberrant signaling in transgenic mice expressing the human herpesvirus-8 K1 gene. J Natl Cancer Inst. 2002 Jun 19; 94(12):926-35. PMID: 12072546.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    90. Prakash O, Tang ZY, Zhou P, Peng X, Kolls J, Shellito JE, Nelson S. Ethanol decreases the efficiency of phosphorylation of thymidine kinase in a human T-lymphocytic cell line. Alcohol Clin Exp Res. 2002 Mar; 26(3):295-302. PMID: 11923581.
      Citations: 3     Fields:    Translation:HumansCells
    91. Zhao X, Tang ZY, Klumpp B, Wolff-Vorbeck G, Barth H, Levy S, Blum HE, Baumert TF, von Weizs?cker F. Primary hepatocytes of Tupaia belangeri as a potential model for hepatitis C virus infection. J Clin Invest. 2002 Jan; 109(2):221-32. PMID: 11805134; PMCID: PMC150834.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    92. Prakash O, Rodriguez VE, Tang ZY, Zhou P, Coleman R, Dhillon G, Shellito JE, Nelson S. Inhibition of hematopoietic progenitor cell proliferation by ethanol in human immunodeficiency virus type 1 tat-expressing transgenic mice. Alcohol Clin Exp Res. 2001 Mar; 25(3):450-6. PMID: 11290858.
      Citations: 10     Fields:    Translation:AnimalsCells
    93. Prakash O, Tang ZY, He YE, Ali MS, Coleman R, Gill J, Farr G, Samaniego F. Human Kaposi's sarcoma cell-mediated tumorigenesis in human immunodeficiency type 1 tat-expressing transgenic mice. J Natl Cancer Inst. 2000 May 03; 92(9):721-8. PMID: 10793108.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    94. Zheng X, Yang D, Tang Z. [The clinical and pathology study of HBV precore mutant infection in chronic HBV patients]. Zhonghua Gan Zang Bing Za Zhi. 1999 Mar; 7(1):17-9. PMID: 10366977.
      Citations:    Fields:    Translation:HumansCells
    95. Moradpour D, Yang D, Hao L, Blum H, Tang Z, K?ck J. [Implication of mutation of hepatitis C virus 1b interferon sensitivity determining region(NS5A aa 2209-2248) response to interferon alpha therapy in patients with chronic hepatitis C]. J Tongji Med Univ. 1999; 19(2):115-9. PMID: 12840853.
      Citations:    Fields:    Translation:HumansCells
    96. Tang Z, Wang Y, Yu Z, Yang D, Hao L. [Virological and clinical features of patients with sporadic hepatitis C]. Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi. 1997 Jun; 11(2):124-6. PMID: 15619815.
      Citations:    Fields:    Translation:Humans
    97. Yang DL, Yu ZQ, Hao LJ, Tang ZY. [Study of HCV infection and viremia in patients with posttransfusion hepatitis in China]. J Tongji Med Univ. 1995; 15(4):201-4. PMID: 8731923.
      Citations:    Fields:    Translation:HumansCells
    98. Double inv(3)(q21q26.2) in acute myeloid leukemia is resulted from an acquired copy neutral loss of heterozygosity of chromosome 3q and associated with disease progression. Molecular Cytogenetics. 8.
    99. Newly emerged isolated Del(7q) in patients with prior cytotoxic therapies may not always be associated with therapy-related myeloid neoplasms. Modern Pathology.
    100. P53 expression correlates with poorer survival and augments the negative prognostic effect of MYC rearrangement, expression or concurrent MYC/BCL2 expression in diffuse large B-cell lymphoma. Modern Pathology.
    101. Hepatitis G virus infection in Chinese patients with chronic hepatitis B, C or non-A-E. Hepatology Research. 13:133-142.
    102. Sex chromosome loss after allogeneic hematopoietic stem cell transplant in patients with hematologic neoplasms. Molecular Cytogenetics. 9.
    103. The clinical significance of 8q24/MYC rearrangement in chronic lymphocytic leukemia. Modern Pathology.
    104. Clinical significance of acquired loss of the X chromosome in bone marrow. Leukemia Research. 47:109-113.
    105. Simultaneous deletion of 3'ETV6 and 5' EWSR1 genes in blastic plasmacytoid dendritic cell neoplasm. Molecular Cytogenetics. 9.
    106. Role of complexity of variant Philadelphia chromosome in chronic myeloid leukemia in the era of tyrosine kinase inhibitor therapy. Annals of Hematology. 1-4.
    107. Nachweis und Bedeutung von HCV RNS im Speichel, Sperma und Vaginalsekret von Patienten mit Hepatitis C. Journal of Tongji Medical University. 16:11-13.
    108. Impact of trisomy 8 on treatment response and survival of patients with chronic myelogenous leukemia in the era of tyrosine kinase inhibitors. Leukemia.
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