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CHANGYING JIANG

TitleAssistant Professor
InstitutionMD Anderson
DepartmentLymphoma-Myeloma
Address1515 Holcombe Blvd.
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zhao S, Kanagal-Shamanna R, Navsaria L, Ok CY, Zhang S, Nomie K, Han G, Hao D, Hill HA, Jiang C, Yao Y, Nastoupil L, Westin J, Fayad L, Nair R, Steiner R, Ahmed S, Samaniego F, Iyer SP, Oriabure O, Chen W, Song X, Zhang J, Badillo M, Moghrabi O, Aranda J, Tang G, Yin CC, Patel K, Medeiros LJ, Li S, Vega F, Thirumurthi S, Xu G, Neelapu S, Flowers CR, Romaguera J, Fowler N, Wang L, Wang ML, Jain P. Efficacy of venetoclax in high risk relapsed mantle cell lymphoma (MCL) - outcomes and mutation profile from venetoclax resistant MCL patients. Am J Hematol. 2020 06; 95(6):623-629. PMID: 32239765.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    2. Jain P, Zhang S, Kanagal-Shamanna R, Ok CY, Nomie K, Gonzalez GN, Gonzalez-Pagan O, Hill HA, Lee HJ, Fayad L, Westin J, Nastoupil L, Hagemeister F, Chen W, Oriabure O, Badillo M, Jiang C, Yixin Y, Li S, Tang G, Yin CC, Patel KP, Medeiros LJ, Nair R, Ahmed S, Iyer SP, Thirumurthi S, Champlin R, Xu G, Tinsu P, Santos D, Wang R, Han G, Zhang J, Song X, Neelapu S, Romaguera J, Futreal A, Flowers C, Fowler N, Wang L, Wang ML. Genomic profiles and clinical outcomes of de novo blastoid/pleomorphic MCL are distinct from those of transformed MCL. Blood Adv. 2020 03 24; 4(6):1038-1050. PMID: 32191807; PMCID: PMC7094021.
      Citations: 10     Fields:    Translation:Humans
    3. Wang J, Wang J, Lopez E, Guo H, Zhang H, Liu Y, Chen Z, Huang S, Zhou S, Leeming A, Zhang RJ, Jung D, Shi H, Grundman H, Doakes D, Cui K, Jiang C, Ahmed M, Nomie K, Fang B, Wang M, Yao Y, Zhang L. Repurposing auranofin to treat TP53-mutated or PTEN-deleted refractory B-cell lymphoma. Blood Cancer J. 2019 11 28; 9(12):95. PMID: 31780660; PMCID: PMC6882812.
      Citations: 7     Fields:    Translation:HumansCells
    4. Li CJ, Jiang C, Liu Y, Bell T, Ma W, Ye Y, Huang S, Guo H, Zhang H, Wang L, Wang J, Nomie K, Zhang L, Wang M. Pleiotropic Action of Novel Bruton's Tyrosine Kinase Inhibitor BGB-3111 in Mantle Cell Lymphoma. Mol Cancer Ther. 2019 02; 18(2):267-277. PMID: 30413649; PMCID: PMC6363842.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    5. Guo H, Zeng D, Zhang H, Bell T, Yao J, Liu Y, Huang S, Li CJ, Lorence E, Zhou S, Gong T, Jiang C, Ahmed M, Yao Y, Nomie KJ, Zhang L, Wang M. Dual inhibition of PI3K signaling and histone deacetylation halts proliferation and induces lethality in mantle cell lymphoma. Oncogene. 2019 03; 38(11):1802-1814. PMID: 30361685.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    6. Wang T, Fan C, Yao A, Xu X, Zheng G, You Y, Jiang C, Zhao X, Hou Y, Hung MC, Lin X. The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells. Immunity. 2018 09 18; 49(3):504-514.e4. PMID: 30231984; PMCID: PMC6880241.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    7. Zheng G, Jiang C, Li Y, Yang D, Ma Y, Zhang B, Li X, Zhang P, Hu X, Zhao X, Du J, Lin X. TMEM43-S358L mutation enhances NF-?B-TGF? signal cascade in arrhythmogenic right ventricular dysplasia/cardiomyopathy. Protein Cell. 2019 02; 10(2):104-119. PMID: 29980933; PMCID: PMC6340891.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    8. Huang S, Jiang C, Zhang H, Bell T, Guo H, Liu Y, Yao Y, Zeng D, Ahmed M, Nomie K, Zhang L, Wang M. The CD20-specific engineered toxin antibody MT-3724 exhibits lethal effects against mantle cell lymphoma. Blood Cancer J. 2018 03 20; 8(3):33. PMID: 29559616; PMCID: PMC5861115.
      Citations: 3     Fields:    Translation:HumansCells
    9. Liu Y, Yin Y, Zhang Z, Li CJ, Zhang H, Zhang D, Jiang C, Nomie K, Zhang L, Wang ML, Zhao G. Structural optimization elaborates novel potent Akt inhibitors with promising anticancer activity. Eur J Med Chem. 2017 Sep 29; 138:543-551. PMID: 28704757.
      Citations: 5     Fields:    Translation:HumansCells
    10. Zhao X, Guo Y, Jiang C, Chang Q, Zhang S, Luo T, Zhang B, Jia X, Hung MC, Dong C, Lin X. JNK1 negatively controls antifungal innate immunity by suppressing CD23 expression. Nat Med. 2017 Mar; 23(3):337-346. PMID: 28112734; PMCID: PMC5592785.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    11. Wang T, Pan D, Zhou Z, You Y, Jiang C, Zhao X, Lin X. Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut. PLoS Pathog. 2016 06; 12(6):e1005662. PMID: 27280399; PMCID: PMC4900642.
      Citations: 38     Fields:    Translation:Animals
    12. Jiang C, Zhou Z, Quan Y, Zhang S, Wang T, Zhao X, Morrison C, Heise MT, He W, Miller MS, Lin X. CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection. Cell Rep. 2016 Mar 15; 14(10):2389-401. PMID: 26947079; PMCID: PMC5842788.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    13. Pan D, Zhu Y, Zhou Z, Wang T, You H, Jiang C, Lin X. The CBM Complex Underwrites NF-?B Activation to Promote HER2-Associated Tumor Malignancy. Mol Cancer Res. 2016 Jan; 14(1):93-102. PMID: 26392569.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    14. Jiang C, Lin X. Analysis of epidermal growth factor-induced NF-?B signaling. Methods Mol Biol. 2015; 1280:75-102. PMID: 25736745.
      Citations: 5     Fields:    Translation:HumansCells
    15. Zhao XQ, Zhu LL, Chang Q, Jiang C, You Y, Luo T, Jia XM, Lin X. C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-?B activation. J Biol Chem. 2014 Oct 24; 289(43):30052-62. PMID: 25202022; PMCID: PMC4208012.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    16. Zhu LL, Zhao XQ, Jiang C, You Y, Chen XP, Jiang YY, Jia XM, Lin X. C-type lectin receptors Dectin-3 and Dectin-2 form a heterodimeric pattern-recognition receptor for host defense against fungal infection. Immunity. 2013 Aug 22; 39(2):324-34. PMID: 23911656.
      Citations: 144     Fields:    Translation:HumansAnimalsCells
    17. Jiang C, Lin X. Regulation of NF-?B by the CARD proteins. Immunol Rev. 2012 Mar; 246(1):141-53. PMID: 22435552; PMCID: PMC3339759.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    18. Jiang T, Grabiner B, Zhu Y, Jiang C, Li H, You Y, Lang J, Hung MC, Lin X. CARMA3 is crucial for EGFR-Induced activation of NF-?B and tumor progression. Cancer Res. 2011 Mar 15; 71(6):2183-92. PMID: 21406399; PMCID: PMC3059846.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    19. Jiang C, Komazin-Meredith G, Tian W, Coen DM, Hwang CB. Mutations that increase DNA binding by the processivity factor of herpes simplex virus affect virus production and DNA replication fidelity. J Virol. 2009 Aug; 83(15):7573-80. PMID: 19474109; PMCID: PMC2708624.
      Citations: 9     Fields:    Translation:AnimalsCells
    20. Jiang C, Hwang YT, Wang G, Randell JC, Coen DM, Hwang CB. Herpes simplex virus mutants with multiple substitutions affecting DNA binding of UL42 are impaired for viral replication and DNA synthesis. J Virol. 2007 Nov; 81(21):12077-9. PMID: 17715219; PMCID: PMC2168780.
      Citations: 8     Fields:    Translation:AnimalsCells
    21. Jiang C, Hwang YT, Randell JC, Coen DM, Hwang CB. Mutations that decrease DNA binding of the processivity factor of the herpes simplex virus DNA polymerase reduce viral yield, alter the kinetics of viral DNA replication, and decrease the fidelity of DNA replication. J Virol. 2007 Apr; 81(7):3495-502. PMID: 17229696; PMCID: PMC1866068.
      Citations: 12     Fields:    Translation:AnimalsCells
    22. Jiang C, Hwang YT, Hwang CB. Herpes simplex virus type 1 recombinants without the oriL sequence replicate DNA with increased fidelity. Virology. 2006 Apr 10; 347(2):277-85. PMID: 16427677.
      Citations: 2     Fields:    Translation:AnimalsCells
    23. Corcoran CA, Luo X, He Q, Jiang C, Huang Y, Sheikh MS. Genotoxic and endoplasmic reticulum stresses differentially regulate TRB3 expression. Cancer Biol Ther. 2005 Oct; 4(10):1063-7. PMID: 16294033.
      Citations: 27     Fields:    Translation:HumansCells
    24. Randell JC, Komazin G, Jiang C, Hwang CB, Coen DM. Effects of substitutions of arginine residues on the basic surface of herpes simplex virus UL42 support a role for DNA binding in processive DNA synthesis. J Virol. 2005 Sep; 79(18):12025-34. PMID: 16140778; PMCID: PMC1212618.
      Citations: 16     Fields:    Translation:Cells
    25. TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression. Oncogene.
    26. The CBM complex underwrites NF-κB activation to promote HER2-associated tumor malignancy. Molecular Cancer Research. 14:93-102.
    27. Dectin-3 Deficiency Promotes Colitis Development due to Impaired Antifungal Innate Immune Responses in the Gut. PLoS Pathogens. 12.
    28. MALT1 is required for EGFR-induced NF-κB activation and contributes to EGFR-driven lung cancer progression. Oncogene.
    29. CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection. Cell Reports. 14:2389-2401.
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