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WAH CHIU

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
AddressOne Baylor Plaza
Houston TX 77030
Email
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    Other Positions
    TitleAdjunct Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Virology & Microbiology
    DivisionMolecular Virology & Microbiology

    TitleAdjunct Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Biochemistry & Molecular Biology
    DivisionBiochemistry & Molecular Biology


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    1996Alexander von Humboldt Research Prize, Alexander von Humboldt Foundation
    2008Elected Academician of Academia Sinica, Taiwan, Academia Sinica, Taiwan
    2010Distinguished Service Professor, Baylor College of Medicine, Baylor College of Medicine
    2012Elected Member of National Academy of Sciences, United States National Academy of Sciences
    2013Elected Member of Academy of Medicine, Engineering, and Science of Texas, The Academy of Medicine, Engineering, and Science of Texas
    2013Distinguished Faculty Award of Baylor College of Medicine Alumni Association , Baylor College of Medicine Alumni Association
    2014Honorary Doctorate of Philosophy at the University of Helsinki, University of Helsinki
    2014Microscopy Society of America Distinguished Scientist Award , Microscopy Society of America
    2015Barbara and Corbin J. Robertson Jr. Presidential Award for Excellence in Education, Baylor College of Medicine

    Collapse Overview 
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    Cryo-Electron Microscopy; Cryo-Electron Tomography; Structural Biophysics; Computational Biology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chiu W, Downing KH. Editorial overview: Cryo Electron Microscopy: Exciting advances in CryoEM Herald a new era in structural biology. Curr Opin Struct Biol. 2017 Aug 08. PMID: 28801059.
      View in: PubMed
    2. Kaelber JT, Hryc CF, Chiu W. Electron Cryomicroscopy of Viruses at Near-Atomic Resolutions. Annu Rev Virol. 2017 Jul 17. PMID: 28715974.
      View in: PubMed
    3. Roh SH, Hryc CF, Jeong HH, Fei X, Jakana J, Lorimer GH, Chiu W. Subunit conformational variation within individual GroEL oligomers resolved by Cryo-EM. Proc Natl Acad Sci U S A. 2017 Jul 14. PMID: 28710336.
      View in: PubMed
    4. Wang Q, Irobalieva RN, Chiu W, Schmid MF, Fogg JM, Zechiedrich L, Pettitt BM. Influence of DNA sequence on the structure of minicircles under torsional stress. Nucleic Acids Res. 2017 Jun 13. PMID: 28609782.
      View in: PubMed
    5. Chiu W, Holton J, Langan P, Sauter NK, Schlichting I, Terwilliger T, Martin JL, Read RJ, Wakatsuki S. Responses to `Atomic resolution': a badly abused term in structural biology. Acta Crystallogr D Struct Biol. 2017 Apr 01; 73(Pt 4):381-383. PMID: 28375150.
      View in: PubMed
    6. Murata K, Zhang Q, Gerardo Galaz-Montoya J, Fu C, Coleman ML, Osburne MS, Schmid MF, Sullivan MB, Chisholm SW, Chiu W. Visualizing Adsorption of Cyanophage P-SSP7 onto Marine Prochlorococcus. Sci Rep. 2017 Mar 10; 7:44176. PMID: 28281671.
      View in: PubMed
    7. Hryc CF, Chen DH, Afonine PV, Jakana J, Wang Z, Haase-Pettingell C, Jiang W, Adams PD, King JA, Schmid MF, Chiu W. Accurate model annotation of a near-atomic resolution cryo-EM map. Proc Natl Acad Sci U S A. 2017 Mar 07. PMID: 28270620.
      View in: PubMed
    8. Luengo I, Darrow MC, Spink MC, Sun Y, Dai W, He CY, Chiu W, Pridmore T, Ashton AW, Duke EM, Basham M, French AP. SuRVoS: Super-Region Volume Segmentation workbench. J Struct Biol. 2017 Feb 27. PMID: 28246039.
      View in: PubMed
    9. Erasmus JH, Auguste AJ, Kaelber JT, Luo H, Rossi SL, Fenton K, Leal G, Kim DY, Chiu W, Wang T, Frolov I, Nasar F, Weaver SC. A chikungunya fever vaccine utilizing an insect-specific virus platform. Nat Med. 2016 Dec 19. PMID: 27991917.
      View in: PubMed
    10. Chiu WK, Lam WC, Chu NH, Mok CK, Tung WK, Leung FY, Ting SM. Sexual violence cases in a hospital setting in Hong Kong: victims' demographic, event characteristics, and management. Hong Kong Med J. 2016 Dec; 22(6):576-81. PMID: 27779096.
      View in: PubMed
    11. Shen K, Calamini B, Fauerbach JA, Ma B, Shahmoradian SH, Serrano Lachapel IL, Chiu W, Lo DC, Frydman J. Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract. Elife. 2016 Oct 18; 5. PMID: 27751235.
      View in: PubMed
    12. Zhao X, Chen XQ, Han E, Hu Y, Paik P, Ding Z, Overman J, Lau AL, Shahmoradian SH, Chiu W, Thompson LM, Wu C, Mobley WC. TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington's disease. Proc Natl Acad Sci U S A. 2016 Sep 20; 113(38):E5655-64. PMID: 27601642.
      View in: PubMed
    13. Roh SH, Kasembeli MM, Galaz-Montoya JG, Chiu W, Tweardy DJ. Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions. Biophys J. 2016 Jun 7; 110(11):2377-85. PMID: 27276256; PMCID: PMC4906440 [Available on 06/07/17].
    14. Veneziano R, Ratanalert S, Zhang K, Zhang F, Yan H, Chiu W, Bathe M. Designer nanoscale DNA assemblies programmed from the top down. Science. 2016 Jun 24; 352(6293):1534. PMID: 27229143.
      View in: PubMed
    15. Hecksel CW, Darrow MC, Dai W, Galaz-Montoya JG, Chin JA, Mitchell PG, Chen S, Jakana J, Schmid MF, Chiu W. Quantifying Variability of Manual Annotation in Cryo-Electron Tomograms. Microsc Microanal. 2016 Jun; 22(3):487-96. PMID: 27225525.
      View in: PubMed
    16. Galaz-Montoya JG, Hecksel CW, Baldwin PR, Wang E, Weaver SC, Schmid MF, Ludtke SJ, Chiu W. Alignment algorithms and per-particle CTF correction for single particle cryo-electron tomography. J Struct Biol. 2016 Jun; 194(3):383-94. PMID: 27016284; PMCID: PMC4846534 [Available on 06/01/17].
    17. Marabini R, Ludtke SJ, Murray SC, Chiu W, de la Rosa-Trevín JM, Patwardhan A, Heymann JB, Carazo JM. The Electron Microscopy eXchange (EMX) initiative. J Struct Biol. 2016 May; 194(2):156-63. PMID: 26873784.
      View in: PubMed
    18. Pintilie G, Chen DH, Haase-Pettingell CA, King JA, Chiu W. Resolution and Probabilistic Models of Components in CryoEM Maps of Mature P22 Bacteriophage. Biophys J. 2016 Feb 23; 110(4):827-39. PMID: 26743049; PMCID: PMC4775875 [Available on 02/23/17].
    19. Roh SH, Kasembeli M, Galaz-Montoya JG, Trnka M, Lau WC, Burlingame A, Chiu W, Tweardy DJ. Chaperonin TRiC/CCT Modulates the Folding and Activity of Leukemogenic Fusion Oncoprotein AML1-ETO. J Biol Chem. 2016 Feb 26; 291(9):4732-41. PMID: 26706127; PMCID: PMC4813495 [Available on 02/26/17].
    20. Lawson CL, Patwardhan A, Baker ML, Hryc C, Garcia ES, Hudson BP, Lagerstedt I, Ludtke SJ, Pintilie G, Sala R, Westbrook JD, Berman HM, Kleywegt GJ, Chiu W. EMDataBank unified data resource for 3DEM. Nucleic Acids Res. 2016 Jan 4; 44(D1):D396-403. PMID: 26578576.
      View in: PubMed
    21. Roh SH, Kasembeli M, Bakthavatsalam D, Chiu W, Tweardy DJ. Contribution of the Type II Chaperonin, TRiC/CCT, to Oncogenesis. Int J Mol Sci. 2015; 16(11):26706-20. PMID: 26561808.
      View in: PubMed
    22. Wang R, Stone RL, Kaelber JT, Rochat RH, Nick AM, Vijayan KV, Afshar-Kharghan V, Schmid MF, Dong JF, Sood AK, Chiu W. Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer. Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46):14266-14271. PMID: 26578771.
      View in: PubMed
    23. Irobalieva RN, Fogg JM, Catanese DJ, Sutthibutpong T, Chen M, Barker AK, Ludtke SJ, Harris SA, Schmid MF, Chiu W, Zechiedrich L. Erratum: Structural diversity of supercoiled DNA. Nat Commun. 2015; 6:8851. PMID: 26511109.
      View in: PubMed
    24. Fan G, Baker ML, Wang Z, Baker MR, Sinyagovskiy PA, Chiu W, Ludtke SJ, Serysheva II. Gating machinery of InsP3R channels revealed by electron cryomicroscopy. Nature. 2015 Nov 19; 527(7578):336-41. PMID: 26458101.
      View in: PubMed
    25. Irobalieva RN, Fogg JM, Catanese DJ, Sutthibutpong T, Chen M, Barker AK, Ludtke SJ, Harris SA, Schmid MF, Chiu W, Zechiedrich L. Structural diversity of supercoiled DNA. Nat Commun. 2015; 6:8440. PMID: 26455586.
      View in: PubMed
    26. Lu J, Trnka MJ, Roh SH, Robinson PJ, Shiau C, Fujimori DG, Chiu W, Burlingame AL, Guan S. Improved Peak Detection and Deconvolution of Native Electrospray Mass Spectra from Large Protein Complexes. J Am Soc Mass Spectrom. 2015 Dec; 26(12):2141-51. PMID: 26323614.
      View in: PubMed
    27. Du D, Voss J, Wang Z, Chiu W, Luisi BF. The pseudo-atomic structure of an RND-type tripartite multidrug efflux pump. Biol Chem. 2015 Sep; 396(9-10):1073-82. PMID: 25803077.
      View in: PubMed
    28. Tan Z, Dai W, van Erp TG, Overman J, Demuro A, Digman MA, Hatami A, Albay R, Sontag EM, Potkin KT, Ling S, Macciardi F, Bunney WE, Long JD, Paulsen JS, Ringman JM, Parker I, Glabe C, Thompson LM, Chiu W, Potkin SG. Huntington's disease cerebrospinal fluid seeds aggregation of mutant huntingtin. Mol Psychiatry. 2015 Nov; 20(11):1286-93. PMID: 26100538; PMCID: PMC4718563.
    29. Sali A, Berman HM, Schwede T, Trewhella J, Kleywegt G, Burley SK, Markley J, Nakamura H, Adams P, Bonvin AM, Chiu W, Peraro MD, Di Maio F, Ferrin TE, Grünewald K, Gutmanas A, Henderson R, Hummer G, Iwasaki K, Johnson G, Lawson CL, Meiler J, Marti-Renom MA, Montelione GT, Nilges M, Nussinov R, Patwardhan A, Rappsilber J, Read RJ, Saibil H, Schröder GF, Schwieters CD, Seidel CA, Svergun D, Topf M, Ulrich EL, Velankar S, Westbrook JD. Outcome of the First wwPDB Hybrid/Integrative Methods Task Force Workshop. Structure. 2015 Jul 7; 23(7):1156-67. PMID: 26095030.
      View in: PubMed
    30. Darrow MC, Sergeeva OA, Isas JM, Galaz-Montoya JG, King JA, Langen R, Schmid MF, Chiu W. Structural Mechanisms of Mutant Huntingtin Aggregation Suppression by the Synthetic Chaperonin-like CCT5 Complex Explained by Cryoelectron Tomography. J Biol Chem. 2015 Jul 10; 290(28):17451-61. PMID: 25995452.
      View in: PubMed
    31. Marabini R, Carragher B, Chen S, Chen J, Cheng A, Downing KH, Frank J, Grassucci RA, Bernard Heymann J, Jiang W, Jonic S, Liao HY, Ludtke SJ, Patwari S, Piotrowski AL, Quintana A, Sorzano CO, Stahlberg H, Vargas J, Voss NR, Chiu W, Carazo JM. CTF Challenge: Result summary. J Struct Biol. 2015 Jun; 190(3):348-59. PMID: 25913484.
      View in: PubMed
    32. Leung DW, Borek D, Luthra P, Binning JM, Anantpadma M, Liu G, Harvey IB, Su Z, Endlich-Frazier A, Pan J, Shabman RS, Chiu W, Davey RA, Otwinowski Z, Basler CF, Amarasinghe GK. An Intrinsically Disordered Peptide from Ebola Virus VP35 Controls Viral RNA Synthesis by Modulating Nucleoprotein-RNA Interactions. Cell Rep. 2015 Apr 21; 11(3):376-89. PMID: 25865894; PMCID: PMC4599368.
    33. Yi P, Wang Z, Feng Q, Pintilie GD, Foulds CE, Lanz RB, Ludtke SJ, Schmid MF, Chiu W, O'Malley BW. Structure of a biologically active estrogen receptor-coactivator complex on DNA. Mol Cell. 2015 Mar 19; 57(6):1047-58. PMID: 25728767; PMCID: PMC4369429.
    34. Hong C, Pietilä MK, Fu CJ, Schmid MF, Bamford DH, Chiu W. Lemon-shaped halo archaeal virus His1 with uniform tail but variable capsid structure. Proc Natl Acad Sci U S A. 2015 Feb 24; 112(8):2449-54. PMID: 25675521; PMCID: PMC4345568.
    35. Hong C, Oksanen HM, Liu X, Jakana J, Bamford DH, Chiu W. A structural model of the genome packaging process in a membrane-containing double stranded DNA virus. PLoS Biol. 2014 Dec; 12(12):e1002024. PMID: 25514469; PMCID: PMC4267777.
    36. Dai W, Fu C, Khant HA, Ludtke SJ, Schmid MF, Chiu W. Zernike phase-contrast electron cryotomography applied to marine cyanobacteria infected with cyanophages. Nat Protoc. 2014 Nov; 9(11):2630-42. PMID: 25321408; PMCID: PMC4371552.
    37. Patwardhan A, Ashton A, Brandt R, Butcher S, Carzaniga R, Chiu W, Collinson L, Doux P, Duke E, Ellisman MH, Franken E, Grünewald K, Heriche JK, Koster A, Kühlbrandt W, Lagerstedt I, Larabell C, Lawson CL, Saibil HR, Sanz-García E, Subramaniam S, Verkade P, Swedlow JR, Kleywegt GJ. A 3D cellular context for the macromolecular world. Nat Struct Mol Biol. 2014 Oct; 21(10):841-5. PMID: 25289590; PMCID: PMC4346196.
    38. Afonin KA, Viard M, Koyfman AY, Martins AN, Kasprzak WK, Panigaj M, Desai R, Santhanam A, Grabow WW, Jaeger L, Heldman E, Reiser J, Chiu W, Freed EO, Shapiro BA. Multifunctional RNA nanoparticles. Nano Lett. 2014 Oct 8; 14(10):5662-71. PMID: 25267559.
      View in: PubMed
    39. Wang Z, Hryc CF, Bammes B, Afonine PV, Jakana J, Chen DH, Liu X, Baker ML, Kao C, Ludtke SJ, Schmid MF, Adams PD, Chiu W. An atomic model of brome mosaic virus using direct electron detection and real-space optimization. Nat Commun. 2014; 5:4808. PMID: 25185801; PMCID: PMC4155512.
    40. Gipson P, Baker ML, Raytcheva D, Haase-Pettingell C, Piret J, King JA, Chiu W. Protruding knob-like proteins violate local symmetries in an icosahedral marine virus. Nat Commun. 2014; 5:4278. PMID: 24985522; PMCID: PMC4102127.
    41. Dai W, Schmid MF, King JA, Chiu W. Identifying the assembly pathway of cyanophage inside the marine bacterium using electron cryo-tomography. Microb Cell. 2014 Jun 1; 1(1):45-47. PMID: 25419524.
      View in: PubMed
    42. Kasembeli M, Lau WC, Roh SH, Eckols TK, Frydman J, Chiu W, Tweardy DJ. Modulation of STAT3 folding and function by TRiC/CCT chaperonin. PLoS Biol. 2014 Apr; 12(4):e1001844. PMID: 24756126; PMCID: PMC3995649.
    43. Du D, Wang Z, James NR, Voss JE, Klimont E, Ohene-Agyei T, Venter H, Chiu W, Luisi BF. Structure of the AcrAB-TolC multidrug efflux pump. Nature. 2014 May 22; 509(7501):512-5. PMID: 24747401; PMCID: PMC4361902.
    44. Shahmoradian SH, Galiano MR, Wu C, Chen S, Rasband MN, Mobley WC, Chiu W. Preparation of primary neurons for visualizing neurites in a frozen-hydrated state using cryo-electron tomography. J Vis Exp. 2014; (84):e50783. PMID: 24561719; PMCID: PMC4089403.
    45. Leung TF, Lam DS, Miu TY, Hon KL, Chau CS, Ku SW, Lee RS, Chow PY, Chiu WK, Ng DK. Epidemiology and risk factors for severe respiratory syncytial virus infections requiring pediatric intensive care admission in Hong Kong children. Infection. 2014 Apr; 42(2):343-50. PMID: 24277597.
      View in: PubMed
    46. Hoersch D, Roh SH, Chiu W, Kortemme T. Reprogramming an ATP-driven protein machine into a light-gated nanocage. Nat Nanotechnol. 2013 Dec; 8(12):928-32. PMID: 24270642; PMCID: PMC3859876.
    47. Dai W, Fu C, Raytcheva D, Flanagan J, Khant HA, Liu X, Rochat RH, Haase-Pettingell C, Piret J, Ludtke SJ, Nagayama K, Schmid MF, King JA, Chiu W. Visualizing virus assembly intermediates inside marine cyanobacteria. Nature. 2013 Oct 31; 502(7473):707-10. PMID: 24107993; PMCID: PMC3984937.
    48. Wagner G, Chiu W. Exploring new limits in complex biological structures. Curr Opin Struct Biol. 2013 Oct; 23(5):704-6. PMID: 24076042.
      View in: PubMed
    49. Baker ML, Hryc CF, Zhang Q, Wu W, Jakana J, Haase-Pettingell C, Afonine PV, Adams PD, King JA, Jiang W, Chiu W. Validated near-atomic resolution structure of bacteriophage epsilon15 derived from cryo-EM and modeling. Proc Natl Acad Sci U S A. 2013 Jul 23; 110(30):12301-6. PMID: 23840063; PMCID: PMC3725109.
    50. Shahmoradian SH, Galaz-Montoya JG, Schmid MF, Cong Y, Ma B, Spiess C, Frydman J, Ludtke SJ, Chiu W. TRiC's tricks inhibit huntingtin aggregation. Elife. 2013; 2:e00710. PMID: 23853712; PMCID: PMC3707056.
    51. Chen DH, Madan D, Weaver J, Lin Z, Schröder GF, Chiu W, Rye HS. Visualizing GroEL/ES in the act of encapsulating a folding protein. Cell. 2013 Jun 6; 153(6):1354-65. PMID: 23746846; PMCID: PMC3695626.
    52. DiMaio F, Zhang J, Chiu W, Baker D. Cryo-EM model validation using independent map reconstructions. Protein Sci. 2013 Jun; 22(6):865-8. PMID: 23592445; PMCID: PMC3690725.
    53. Murray SC, Flanagan J, Popova OB, Chiu W, Ludtke SJ, Serysheva II. Validation of cryo-EM structure of IP?R1 channel. Structure. 2013 Jun 4; 21(6):900-9. PMID: 23707684; PMCID: PMC3696195.
    54. Sergeeva OA, Chen B, Haase-Pettingell C, Ludtke SJ, Chiu W, King JA. Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers. J Biol Chem. 2013 Jun 14; 288(24):17734-44. PMID: 23612981; PMCID: PMC3682573.
    55. Zhang Q, Dai X, Cong Y, Zhang J, Chen DH, Dougherty MT, Wang J, Ludtke SJ, Schmid MF, Chiu W. Cryo-EM structure of a molluscan hemocyanin suggests its allosteric mechanism. Structure. 2013 Apr 2; 21(4):604-13. PMID: 23541894; PMCID: PMC3657317.
    56. Rees I, Langley E, Chiu W, Ludtke SJ. EMEN2: an object oriented database and electronic lab notebook. Microsc Microanal. 2013 Feb; 19(1):1-10. PMID: 23360752; PMCID: PMC3907281.
    57. Gilliam JC, Chang JT, Sandoval IM, Zhang Y, Li T, Pittler SJ, Chiu W, Wensel TG. Three-dimensional architecture of the rod sensory cilium and its disruption in retinal neurodegeneration. Cell. 2012 Nov 21; 151(5):1029-41. PMID: 23178122; PMCID: PMC3582337.
    58. Pintilie G, Chiu W. Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in cryo-EM density maps. Biopolymers. 2012 Sep; 97(9):742-60. PMID: 22696409; PMCID: PMC3402182.
    59. Baker ML, Baker MR, Hryc CF, Ju T, Chiu W. Gorgon and pathwalking: macromolecular modeling tools for subnanometer resolution density maps. Biopolymers. 2012 Sep; 97(9):655-68. PMID: 22696403; PMCID: PMC3899894.
    60. Ludtke SJ, Lawson CL, Kleywegt GJ, Berman H, Chiu W. The 2010 cryo-EM modeling challenge. Biopolymers. 2012 Sep; 97(9):651-4. PMID: 22696402.
      View in: PubMed
    61. Leitner A, Joachimiak LA, Bracher A, Mönkemeyer L, Walzthoeni T, Chen B, Pechmann S, Holmes S, Cong Y, Ma B, Ludtke S, Chiu W, Hartl FU, Aebersold R, Frydman J. The molecular architecture of the eukaryotic chaperonin TRiC/CCT. Structure. 2012 May 9; 20(5):814-25. PMID: 22503819; PMCID: PMC3350567.
    62. Yu CC, Li AM, Au CT, McManus AM, So RC, Lam HS, Chu WC, So HK, Chiu WK, Leung CW, Yau YS, Fok TF, Sung RY. Follow up of aerobic capacity in children affected by severe acute respiratory syndrome. Respirology. 2012 Apr; 17(3):513-8. PMID: 22212464.
      View in: PubMed
    63. Ni P, Wang Z, Ma X, Das NC, Sokol P, Chiu W, Dragnea B, Hagan M, Kao CC. An examination of the electrostatic interactions between the N-terminal tail of the Brome Mosaic Virus coat protein and encapsidated RNAs. J Mol Biol. 2012 Jun 22; 419(5):284-300. PMID: 22472420; PMCID: PMC3360812.
    64. Baker MR, Rees I, Ludtke SJ, Chiu W, Baker ML. Constructing and validating initial C? models from subnanometer resolution density maps with pathwalking. Structure. 2012 Mar 7; 20(3):450-63. PMID: 22405004; PMCID: PMC3307788.
    65. Fauerbach JA, Yushchenko DA, Shahmoradian SH, Chiu W, Jovin TM, Jares-Erijman EA. Supramolecular non-amyloid intermediates in the early stages of ?-synuclein aggregation. Biophys J. 2012 Mar 7; 102(5):1127-36. PMID: 22404935; PMCID: PMC3296045.
    66. Stone RL, Nick AM, McNeish IA, Balkwill F, Han HD, Bottsford-Miller J, Rupairmoole R, Armaiz-Pena GN, Pecot CV, Coward J, Deavers MT, Vasquez HG, Urbauer D, Landen CN, Hu W, Gershenson H, Matsuo K, Shahzad MM, King ER, Tekedereli I, Ozpolat B, Ahn EH, Bond VK, Wang R, Drew AF, Gushiken F, Lamkin D, Collins K, DeGeest K, Lutgendorf SK, Chiu W, Lopez-Berestein G, Afshar-Kharghan V, Sood AK. Paraneoplastic thrombocytosis in ovarian cancer. N Engl J Med. 2012 Feb 16; 366(7):610-8. PMID: 22335738; PMCID: PMC3296780.
    67. Henderson R, Sali A, Baker ML, Carragher B, Devkota B, Downing KH, Egelman EH, Feng Z, Frank J, Grigorieff N, Jiang W, Ludtke SJ, Medalia O, Penczek PA, Rosenthal PB, Rossmann MG, Schmid MF, Schröder GF, Steven AC, Stokes DL, Westbrook JD, Wriggers W, Yang H, Young J, Berman HM, Chiu W, Kleywegt GJ, Lawson CL. Outcome of the first electron microscopy validation task force meeting. Structure. 2012 Feb 8; 20(2):205-14. PMID: 22325770; PMCID: PMC3328769.
    68. Bammes BE, Rochat RH, Jakana J, Chen DH, Chiu W. Direct electron detection yields cryo-EM reconstructions at resolutions beyond 3/4 Nyquist frequency. J Struct Biol. 2012 Mar; 177(3):589-601. PMID: 22285189; PMCID: PMC3314222.
    69. Chang J, Liu X, Rochat RH, Baker ML, Chiu W. Reconstructing virus structures from nanometer to near-atomic resolutions with cryo-electron microscopy and tomography. Adv Exp Med Biol. 2012; 726:49-90. PMID: 22297510; PMCID: PMC3954858.
    70. Kim TH, Mount CW, Dulken BW, Ramos J, Fu CJ, Khant HA, Chiu W, Gombotz WR, Pun SH. Filamentous, mixed micelles of triblock copolymers enhance tumor localization of indocyanine green in a murine xenograft model. Mol Pharm. 2012 Jan 1; 9(1):135-43. PMID: 22118658; PMCID: PMC3256244.
    71. Cong Y, Schröder GF, Meyer AS, Jakana J, Ma B, Dougherty MT, Schmid MF, Reissmann S, Levitt M, Ludtke SL, Frydman J, Chiu W. Symmetry-free cryo-EM structures of the chaperonin TRiC along its ATPase-driven conformational cycle. EMBO J. 2012 Feb 1; 31(3):720-30. PMID: 22045336; PMCID: PMC3273382.
    72. Ludtke SJ, Tran TP, Ngo QT, Moiseenkova-Bell VY, Chiu W, Serysheva II. Flexible architecture of IP3R1 by Cryo-EM. Structure. 2011 Aug 10; 19(8):1192-9. PMID: 21827954; PMCID: PMC3154621.
    73. Zhang R, Hryc CF, Cong Y, Liu X, Jakana J, Gorchakov R, Baker ML, Weaver SC, Chiu W. 4.4 Å cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus. EMBO J. 2011 Sep 14; 30(18):3854-63. PMID: 21829169; PMCID: PMC3173789.
    74. Hryc CF, Chen DH, Chiu W. Near-atomic-resolution cryo-EM for molecular virology. Curr Opin Virol. 2011 Aug; 1(2):110-7. PMID: 21845206; PMCID: PMC3155204.
    75. Kostyuchenko VA, Jakana J, Liu X, Haddow AD, Aung M, Weaver SC, Chiu W, Lok SM. The structure of barmah forest virus as revealed by cryo-electron microscopy at a 6-angstrom resolution has detailed transmembrane protein architecture and interactions. J Virol. 2011 Sep; 85(18):9327-33. PMID: 21752915; PMCID: PMC3165765.
    76. Koyfman AY, Schmid MF, Gheiratmand L, Fu CJ, Khant HA, Huang D, He CY, Chiu W. Structure of Trypanosoma brucei flagellum accounts for its bihelical motion. Proc Natl Acad Sci U S A. 2011 Jul 5; 108(27):11105-8. PMID: 21690369; PMCID: PMC3131312.
    77. Ng DK, Miu TY, Chiu WK, Hui NT, Chan CH. Validation of Pediatric Index of Mortality 2 in three pediatric intensive care units in Hong Kong. Indian J Pediatr. 2011 Dec; 78(12):1491-4. PMID: 21617907.
      View in: PubMed
    78. Bammes BE, Rochat RH, Jakana J, Chiu W. Practical performance evaluation of a 10k × 10k CCD for electron cryo-microscopy. J Struct Biol. 2011 Sep; 175(3):384-93. PMID: 21619932; PMCID: PMC3150461.
    79. Zhang J, Ma B, DiMaio F, Douglas NR, Joachimiak LA, Baker D, Frydman J, Levitt M, Chiu W. Cryo-EM structure of a group II chaperonin in the prehydrolysis ATP-bound state leading to lid closure. Structure. 2011 May 11; 19(5):633-9. PMID: 21565698; PMCID: PMC3705922.
    80. Lee LP, Chiu WK, Chan HB, Liu KK. Minimally invasive chest drain insertion in children. Hong Kong Med J. 2011 Apr; 17(2):137-40. PMID: 21471594.
      View in: PubMed
    81. Qin G, Li Z, Xia R, Li F, O'Neill BE, Goodwin JT, Khant HA, Chiu W, Li KC. Partially polymerized liposomes: stable against leakage yet capable of instantaneous release for remote controlled drug delivery. Nanotechnology. 2011 Apr 15; 22(15):155605. PMID: 21389566; PMCID: PMC3157042.
    82. Moon JJ, Suh H, Bershteyn A, Stephan MT, Liu H, Huang B, Sohail M, Luo S, Um SH, Khant H, Goodwin JT, Ramos J, Chiu W, Irvine DJ. Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nat Mater. 2011 Mar; 10(3):243-51. PMID: 21336265; PMCID: PMC3077947.
    83. Baker ML, Abeysinghe SS, Schuh S, Coleman RA, Abrams A, Marsh MP, Hryc CF, Ruths T, Chiu W, Ju T. Modeling protein structure at near atomic resolutions with Gorgon. J Struct Biol. 2011 May; 174(2):360-73. PMID: 21296162; PMCID: PMC3078171.
    84. Douglas NR, Reissmann S, Zhang J, Chen B, Jakana J, Kumar R, Chiu W, Frydman J. Dual action of ATP hydrolysis couples lid closure to substrate release into the group II chaperonin chamber. Cell. 2011 Jan 21; 144(2):240-52. PMID: 21241893; PMCID: PMC3055171.
    85. Chen DH, Baker ML, Hryc CF, DiMaio F, Jakana J, Wu W, Dougherty M, Haase-Pettingell C, Schmid MF, Jiang W, Baker D, King JA, Chiu W. Structural basis for scaffolding-mediated assembly and maturation of a dsDNA virus. Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4):1355-60. PMID: 21220301; PMCID: PMC3029737.
    86. Knee KM, Goulet DR, Zhang J, Chen B, Chiu W, King JA. The group II chaperonin Mm-Cpn binds and refolds human ?D crystallin. Protein Sci. 2011 Jan; 20(1):30-41. PMID: 20981710; PMCID: PMC3047059.
    87. Ludtke SJ, Lawson CL, Kleywegt GJ, Berman HM, Chiu W. Workshop on the validation and modeling of electron cryo-microscopy structures of biological nanomachines. Pac Symp Biocomput. 2011; 369-73. PMID: 21121065; PMCID: PMC3617577.
    88. Rochat RH, Liu X, Murata K, Nagayama K, Rixon FJ, Chiu W. Seeing the portal in herpes simplex virus type 1 B capsids. J Virol. 2011 Feb; 85(4):1871-4. PMID: 21106752; PMCID: PMC3028901.
    89. Baird NJ, Ludtke SJ, Khant H, Chiu W, Pan T, Sosnick TR. Discrete structure of an RNA folding intermediate revealed by cryo-electron microscopy. J Am Chem Soc. 2010 Nov 24; 132(46):16352-3. PMID: 21038867; PMCID: PMC2988076.
    90. Bromberg S, Chiu W, Ferrin TE. Workshop on molecular animation. Structure. 2010 Oct 13; 18(10):1261-5. PMID: 20947014; PMCID: PMC3071847.
    91. Lawson CL, Baker ML, Best C, Bi C, Dougherty M, Feng P, van Ginkel G, Devkota B, Lagerstedt I, Ludtke SJ, Newman RH, Oldfield TJ, Rees I, Sahni G, Sala R, Velankar S, Warren J, Westbrook JD, Henrick K, Kleywegt GJ, Berman HM, Chiu W. EMDataBank.org: unified data resource for CryoEM. Nucleic Acids Res. 2011 Jan; 39(Database issue):D456-64. PMID: 20935055; PMCID: PMC3013769.
    92. Miyazaki Y, Irobalieva RN, Tolbert BS, Smalls-Mantey A, Iyalla K, Loeliger K, D'Souza V, Khant H, Schmid MF, Garcia EL, Telesnitsky A, Chiu W, Summers MF. Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography. J Mol Biol. 2010 Dec 17; 404(5):751-72. PMID: 20933521; PMCID: PMC3023341.
    93. Baker ML, Zhang J, Ludtke SJ, Chiu W. Cryo-EM of macromolecular assemblies at near-atomic resolution. Nat Protoc. 2010 Sep; 5(10):1697-708. PMID: 20885381; PMCID: PMC3107675.
    94. Chang JT, Schmid MF, Haase-Pettingell C, Weigele PR, King JA, Chiu W. Visualizing the structural changes of bacteriophage Epsilon15 and its Salmonella host during infection. J Mol Biol. 2010 Oct 1; 402(4):731-40. PMID: 20709082; PMCID: PMC3164490.
    95. Murata K, Liu X, Danev R, Jakana J, Schmid MF, King J, Nagayama K, Chiu W. Zernike phase contrast cryo-electron microscopy and tomography for structure determination at nanometer and subnanometer resolutions. Structure. 2010 Aug 11; 18(8):903-12. PMID: 20696391; PMCID: PMC2925294.
    96. Saha M, Levitt M, Chiu W. MOTIF-EM: an automated computational tool for identifying conserved regions in CryoEM structures. Bioinformatics. 2010 Jun 15; 26(12):i301-9. PMID: 20529921; PMCID: PMC2881380.
    97. Liu X, Zhang Q, Murata K, Baker ML, Sullivan MB, Fu C, Dougherty MT, Schmid MF, Osburne MS, Chisholm SW, Chiu W. Structural changes in a marine podovirus associated with release of its genome into Prochlorococcus. Nat Struct Mol Biol. 2010 Jul; 17(7):830-6. PMID: 20543830; PMCID: PMC2924429.
    98. Haspel N, Moll M, Baker ML, Chiu W, Kavraki LE. Tracing conformational changes in proteins. BMC Struct Biol. 2010; 10 Suppl 1:S1. PMID: 20487508; PMCID: PMC2873824.
    99. Lee LP, Lai MH, Chiu WK, Leung MW, Liu KK, Chan HB. Management of primary spontaneous pneumothorax in Chinese children. Hong Kong Med J. 2010 Apr; 16(2):94-100. PMID: 20354242.
      View in: PubMed
    100. Nakamura N, Shimizu Y, Shinkawa T, Nakata M, Bammes B, Zhang J, Chiu W. Automated specimen search in cryo-TEM observation with DIFF-defocus imaging. J Electron Microsc (Tokyo). 2010; 59(4):299-310. PMID: 20356853; PMCID: PMC3388909.
    101. Pintilie GD, Zhang J, Goddard TD, Chiu W, Gossard DC. Quantitative analysis of cryo-EM density map segmentation by watershed and scale-space filtering, and fitting of structures by alignment to regions. J Struct Biol. 2010 Jun; 170(3):427-38. PMID: 20338243; PMCID: PMC2874196.
    102. Cong Y, Baker ML, Jakana J, Woolford D, Miller EJ, Reissmann S, Kumar RN, Redding-Johanson AM, Batth TS, Mukhopadhyay A, Ludtke SJ, Frydman J, Chiu W. 4.0-A resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement. Proc Natl Acad Sci U S A. 2010 Mar 16; 107(11):4967-72. PMID: 20194787; PMCID: PMC2841888.
    103. Zhang J, Baker ML, Schröder GF, Douglas NR, Reissmann S, Jakana J, Dougherty M, Fu CJ, Levitt M, Ludtke SJ, Frydman J, Chiu W. Mechanism of folding chamber closure in a group II chaperonin. Nature. 2010 Jan 21; 463(7279):379-83. PMID: 20090755; PMCID: PMC2834796.
    104. Sherman MB, Freiberg AN, Razmus D, Yazuka S, Koht C, Hilser VJ, Lemon SM, Brocard AS, Zimmerman D, Chiu W, Watowich SJ, Weaver SC. A Unique BSL-3 Cryo-Electron Microscopy Laboratory at UTMB. Appl Biosaf. 2010; 15(3):130-136. PMID: 21852942.
      View in: PubMed
    105. Ren G, Rudenko G, Ludtke SJ, Deisenhofer J, Chiu W, Pownall HJ. Model of human low-density lipoprotein and bound receptor based on cryoEM. Proc Natl Acad Sci U S A. 2010 Jan 19; 107(3):1059-64. PMID: 20080547; PMCID: PMC2798884.
    106. Bammes BE, Jakana J, Schmid MF, Chiu W. Radiation damage effects at four specimen temperatures from 4 to 100 K. J Struct Biol. 2010 Mar; 169(3):331-41. PMID: 19903530; PMCID: PMC2826528.
    107. Carson J, Ju T, Bello M, Thaller C, Warren J, Kakadiaris IA, Chiu W, Eichele G. Automated pipeline for atlas-based annotation of gene expression patterns: application to postnatal day 7 mouse brain. Methods. 2010 Feb; 50(2):85-95. PMID: 19698790; PMCID: PMC2818703.
    108. DiMaio F, Tyka MD, Baker ML, Chiu W, Baker D. Refinement of protein structures into low-resolution density maps using rosetta. J Mol Biol. 2009 Sep 11; 392(1):181-90. PMID: 19596339; PMCID: PMC3899897.
    109. Cong Y, Zhang Q, Woolford D, Schweikardt T, Khant H, Dougherty M, Ludtke SJ, Chiu W, Decker H. Structural mechanism of SDS-induced enzyme activity of scorpion hemocyanin revealed by electron cryomicroscopy. Structure. 2009 May 13; 17(5):749-58. PMID: 19446530; PMCID: PMC2705691.
    110. Pintilie G, Zhang J, Chiu W, Gossard D. Identifying Components in 3D Density Maps of Protein Nanomachines by Multi-scale Segmentation. IEEE NIH Life Sci Syst Appl Workshop. 2009 Apr 01; 2009:44-47. PMID: 20556220.
      View in: PubMed
    111. Zhang R, Hu X, Khant H, Ludtke SJ, Chiu W, Schmid MF, Frieden C, Lee JM. Interprotofilament interactions between Alzheimer's Abeta1-42 peptides in amyloid fibrils revealed by cryoEM. Proc Natl Acad Sci U S A. 2009 Mar 24; 106(12):4653-8. PMID: 19264960; PMCID: PMC2660777.
    112. Zhang J, Nakamura N, Shimizu Y, Liang N, Liu X, Jakana J, Marsh MP, Booth CR, Shinkawa T, Nakata M, Chiu W. JADAS: a customizable automated data acquisition system and its application to ice-embedded single particles. J Struct Biol. 2009 Jan; 165(1):1-9. PMID: 18926912; PMCID: PMC2634810.
    113. Serysheva II, Ludtke SJ, Baker ML, Cong Y, Topf M, Eramian D, Sali A, Hamilton SL, Chiu W. Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel. Proc Natl Acad Sci U S A. 2008 Jul 15; 105(28):9610-5. PMID: 18621707; PMCID: PMC2474495.
    114. Chen DH, Luke K, Zhang J, Chiu W, Wittung-Stafshede P. Location and flexibility of the unique C-terminal tail of Aquifex aeolicus co-chaperonin protein 10 as derived by cryo-electron microscopy and biophysical techniques. J Mol Biol. 2008 Sep 5; 381(3):707-17. PMID: 18588898; PMCID: PMC2612737.
    115. Wu G, Mikhailovsky A, Khant HA, Fu C, Chiu W, Zasadzinski JA. Remotely triggered liposome release by near-infrared light absorption via hollow gold nanoshells. J Am Chem Soc. 2008 Jul 2; 130(26):8175-7. PMID: 18543914; PMCID: PMC2593911.
    116. Booth CR, Meyer AS, Cong Y, Topf M, Sali A, Ludtke SJ, Chiu W, Frydman J. Mechanism of lid closure in the eukaryotic chaperonin TRiC/CCT. Nat Struct Mol Biol. 2008 Jul; 15(7):746-53. PMID: 18536725; PMCID: PMC2546500.
    117. Chen DH, Jakana J, Liu X, Schmid MF, Chiu W. Achievable resolution from images of biological specimens acquired from a 4k x 4k CCD camera in a 300-kV electron cryomicroscope. J Struct Biol. 2008 Jul; 163(1):45-52. PMID: 18514542; PMCID: PMC2504495.
    118. MacLean HE, Chiu WS, Notini AJ, Axell AM, Davey RA, McManus JF, Ma C, Plant DR, Lynch GS, Zajac JD. Impaired skeletal muscle development and function in male, but not female, genomic androgen receptor knockout mice. FASEB J. 2008 Aug; 22(8):2676-89. PMID: 18390925.
      View in: PubMed
    119. Ludtke SJ, Baker ML, Chen DH, Song JL, Chuang DT, Chiu W. De novo backbone trace of GroEL from single particle electron cryomicroscopy. Structure. 2008 Mar; 16(3):441-8. PMID: 18334219.
      View in: PubMed
    120. Jiang W, Baker ML, Jakana J, Weigele PR, King J, Chiu W. Backbone structure of the infectious epsilon15 virus capsid revealed by electron cryomicroscopy. Nature. 2008 Feb 28; 451(7182):1130-4. PMID: 18305544.
      View in: PubMed
    121. Topf M, Lasker K, Webb B, Wolfson H, Chiu W, Sali A. Protein structure fitting and refinement guided by cryo-EM density. Structure. 2008 Feb; 16(2):295-307. PMID: 18275820; PMCID: PMC2409374.
    122. Chen CY, Ying SH, Yao MS, Chiu WT, Chan WP. Sphenoid sinus osteoma at the sella turcica associated with empty sella: CT and MR imaging findings. AJNR Am J Neuroradiol. 2008 Mar; 29(3):550-1. PMID: 18184833.
      View in: PubMed
    123. Marsh MP, Chang JT, Booth CR, Liang NL, Schmid MF, Chiu W. Modular software platform for low-dose electron microscopy and tomography. J Microsc. 2007 Dec; 228(Pt 3):384-9. PMID: 18045333; PMCID: PMC4384816.
    124. Chiu W, Moffat K. Biophysical methods: structure, dynamics and gorgeous images. Curr Opin Struct Biol. 2007 Oct; 17(5):546-8. PMID: 17959374.
      View in: PubMed
    125. Cong Y, Topf M, Sali A, Matsudaira P, Dougherty M, Chiu W, Schmid MF. Crystallographic conformers of actin in a biologically active bundle of filaments. J Mol Biol. 2008 Jan 11; 375(2):331-6. PMID: 18022194; PMCID: PMC2680129.
    126. Liu X, Jiang W, Jakana J, Chiu W. Averaging tens to hundreds of icosahedral particle images to resolve protein secondary structure elements using a Multi-Path Simulated Annealing optimization algorithm. J Struct Biol. 2007 Oct; 160(1):11-27. PMID: 17698370; PMCID: PMC2039893.
    127. Bello M, Ju T, Carson J, Warren J, Chiu W, Kakadiaris IA. Learning-based segmentation framework for tissue images containing gene expression data. IEEE Trans Med Imaging. 2007 May; 26(5):728-44. PMID: 17518066.
      View in: PubMed
    128. Ju T, Baker ML, Chiu W. Computing a family of skeletons of volumetric models for shape description. Comput Aided Des. 2007 May; 39(5):352-360. PMID: 18449328.
      View in: PubMed
    129. Reissmann S, Parnot C, Booth CR, Chiu W, Frydman J. Essential function of the built-in lid in the allosteric regulation of eukaryotic and archaeal chaperonins. Nat Struct Mol Biol. 2007 May; 14(5):432-40. PMID: 17460696; PMCID: PMC3339572.
    130. Johnson JE, Chiu W. DNA packaging and delivery machines in tailed bacteriophages. Curr Opin Struct Biol. 2007 Apr; 17(2):237-43. PMID: 17395453.
      View in: PubMed
    131. Pope WH, Weigele PR, Chang J, Pedulla ML, Ford ME, Houtz JM, Jiang W, Chiu W, Hatfull GF, Hendrix RW, King J. Genome sequence, structural proteins, and capsid organization of the cyanophage Syn5: a "horned" bacteriophage of marine synechococcus. J Mol Biol. 2007 May 11; 368(4):966-81. PMID: 17383677; PMCID: PMC2971696.
    132. Baker ML, Ju T, Chiu W. Identification of secondary structure elements in intermediate-resolution density maps. Structure. 2007 Jan; 15(1):7-19. PMID: 17223528; PMCID: PMC1810566.
    133. Jiang W, Chiu W. Cryoelectron microscopy of icosahedral virus particles. Methods Mol Biol. 2007; 369:345-63. PMID: 17656759.
      View in: PubMed
    134. Serysheva II, Chiu W, Ludtke SJ. Single-particle electron cryomicroscopy of the ion channels in the excitation-contraction coupling junction. Methods Cell Biol. 2007; 79:407-35. PMID: 17327167.
      View in: PubMed
    135. Chang JT, Schmid MF, Rixon FJ, Chiu W. Electron cryotomography reveals the portal in the herpesvirus capsid. J Virol. 2007 Feb; 81(4):2065-8. PMID: 17151101; PMCID: PMC1797573.
    136. Chen DH, Song JL, Chuang DT, Chiu W, Ludtke SJ. An expanded conformation of single-ring GroEL-GroES complex encapsulates an 86 kDa substrate. Structure. 2006 Nov; 14(11):1711-22. PMID: 17098196.
      View in: PubMed
    137. Baker ML, Jiang W, Wedemeyer WJ, Rixon FJ, Baker D, Chiu W. Ab initio modeling of the herpesvirus VP26 core domain assessed by CryoEM density. PLoS Comput Biol. 2006 Oct 27; 2(10):e146. PMID: 17069457; PMCID: PMC1626159.
    138. Booth CR, Jakana J, Chiu W. Assessing the capabilities of a 4kx4k CCD camera for electron cryo-microscopy at 300kV. J Struct Biol. 2006 Dec; 156(3):556-63. PMID: 17067819.
      View in: PubMed
    139. Marsh MP, Campos SK, Baker ML, Chen CY, Chiu W, Barry MA. Cryoelectron microscopy of protein IX-modified adenoviruses suggests a new position for the C terminus of protein IX. J Virol. 2006 Dec; 80(23):11881-6. PMID: 16987967; PMCID: PMC1642590.
    140. Schmid MF, Paredes AM, Khant HA, Soyer F, Aldrich HC, Chiu W, Shively JM. Structure of Halothiobacillus neapolitanus carboxysomes by cryo-electron tomography. J Mol Biol. 2006 Dec 1; 364(3):526-35. PMID: 17028023; PMCID: PMC1839851.
    141. Chen CY, Chuang YL, Yao MS, Chiu WT, Chen CL, Chan WP. Posterior epidural migration of a sequestrated lumbar disk fragment: MR imaging findings. AJNR Am J Neuroradiol. 2006 Aug; 27(7):1592-4. PMID: 16908587.
      View in: PubMed
    142. Berman HM, Burley SK, Chiu W, Sali A, Adzhubei A, Bourne PE, Bryant SH, Dunbrack RL, Fidelis K, Frank J, Godzik A, Henrick K, Joachimiak A, Heymann B, Jones D, Markley JL, Moult J, Montelione GT, Orengo C, Rossmann MG, Rost B, Saibil H, Schwede T, Standley DM, Westbrook JD. Outcome of a workshop on archiving structural models of biological macromolecules. Structure. 2006 Aug; 14(8):1211-7. PMID: 16955948.
      View in: PubMed
    143. Baker ML, Yu Z, Chiu W, Bajaj C. Automated segmentation of molecular subunits in electron cryomicroscopy density maps. J Struct Biol. 2006 Dec; 156(3):432-41. PMID: 16908194.
      View in: PubMed
    144. Chang J, Weigele P, King J, Chiu W, Jiang W. Cryo-EM asymmetric reconstruction of bacteriophage P22 reveals organization of its DNA packaging and infecting machinery. Structure. 2006 Jun; 14(6):1073-82. PMID: 16730179.
      View in: PubMed
    145. Ju T, Warren J, Carson J, Bello M, Kakadiaris I, Chiu W, Thaller C, Eichele G. 3D volume reconstruction of a mouse brain from histological sections using warp filtering. J Neurosci Methods. 2006 Sep 30; 156(1-2):84-100. PMID: 16580732.
      View in: PubMed
    146. Araç D, Chen X, Khant HA, Ubach J, Ludtke SJ, Kikkawa M, Johnson AE, Chiu W, Südhof TC, Rizo J. Close membrane-membrane proximity induced by Ca(2+)-dependent multivalent binding of synaptotagmin-1 to phospholipids. Nat Struct Mol Biol. 2006 Mar; 13(3):209-17. PMID: 16491093.
      View in: PubMed
    147. Topf M, Baker ML, Marti-Renom MA, Chiu W, Sali A. Refinement of protein structures by iterative comparative modeling and CryoEM density fitting. J Mol Biol. 2006 Apr 14; 357(5):1655-68. PMID: 16490207.
      View in: PubMed
    148. Jiang W, Chang J, Jakana J, Weigele P, King J, Chiu W. Structure of epsilon15 bacteriophage reveals genome organization and DNA packaging/injection apparatus. Nature. 2006 Feb 2; 439(7076):612-6. PMID: 16452981; PMCID: PMC1559657.
    149. Yu CC, Li AM, So RC, McManus A, Ng PC, Chu W, Chan D, Cheng F, Chiu WK, Leung CW, Yau YS, Mo KW, Wong EM, Cheung AY, Leung TF, Sung RY, Fok TF. Longer term follow up of aerobic capacity in children affected by severe acute respiratory syndrome (SARS). Thorax. 2006 Mar; 61(3):240-6. PMID: 16449271; PMCID: PMC2080724.
    150. Passmore LA, Booth CR, Vénien-Bryan C, Ludtke SJ, Fioretto C, Johnson LN, Chiu W, Barford D. Structural analysis of the anaphase-promoting complex reveals multiple active sites and insights into polyubiquitylation. Mol Cell. 2005 Dec 22; 20(6):855-66. PMID: 16364911.
      View in: PubMed
    151. Baker ML, Jiang W, Rixon FJ, Chiu W. Common ancestry of herpesviruses and tailed DNA bacteriophages. J Virol. 2005 Dec; 79(23):14967-70. PMID: 16282496; PMCID: PMC1287596.
    152. Ng YM, Sung RY, So LY, Fong NC, Ho MH, Cheng YW, Lee SH, Mak WC, Wong DM, Yam MC, Kwok KL, Chiu WK. Kawasaki disease in Hong Kong, 1994 to 2000. Hong Kong Med J. 2005 Oct; 11(5):331-5. PMID: 16219951.
      View in: PubMed
    153. Cong Y, Jiang W, Birmanns S, Zhou ZH, Chiu W, Wriggers W. Fast rotational matching of single-particle images. J Struct Biol. 2005 Nov; 152(2):104-12. PMID: 16236526.
      View in: PubMed
    154. Carson JP, Ju T, Lu HC, Thaller C, Xu M, Pallas SL, Crair MC, Warren J, Chiu W, Eichele G. A digital atlas to characterize the mouse brain transcriptome. PLoS Comput Biol. 2005 Sep; 1(4):e41. PMID: 16184189; PMCID: PMC1215388.
    155. Ludtke SJ, Serysheva II, Hamilton SL, Chiu W. The pore structure of the closed RyR1 channel. Structure. 2005 Aug; 13(8):1203-11. PMID: 16084392; PMCID: PMC2983469.
    156. Chiu W, Baker ML, Jiang W, Dougherty M, Schmid MF. Electron cryomicroscopy of biological machines at subnanometer resolution. Structure. 2005 Mar; 13(3):363-72. PMID: 15766537.
      View in: PubMed
    157. Carson JP, Eichele G, Chiu W. A method for automated detection of gene expression required for the establishment of a digital transcriptome-wide gene expression atlas. J Microsc. 2005 Mar; 217(Pt 3):275-81. PMID: 15725131.
      View in: PubMed
    158. Topf M, Baker ML, John B, Chiu W, Sali A. Structural characterization of components of protein assemblies by comparative modeling and electron cryo-microscopy. J Struct Biol. 2005 Feb; 149(2):191-203. PMID: 15681235.
      View in: PubMed
    159. Serysheva II, Hamilton SL, Chiu W, Ludtke SJ. Structure of Ca2+ release channel at 14 A resolution. J Mol Biol. 2005 Jan 21; 345(3):427-31. PMID: 15581887; PMCID: PMC2978512.
    160. Paredes A, Weaver S, Watowich S, Chiu W. Structural biology of old world and new world alphaviruses. Arch Virol Suppl. 2005; (19):179-85. PMID: 16358426.
      View in: PubMed
    161. Bello M, Ju T, Warren J, Carson J, Chiu W, Thaller C, Eichele G, Kakadiaris IA. Hybrid segmentation framework for tissue images containing gene expression data. Med Image Comput Comput Assist Interv. 2005; 8(Pt 1):254-61. PMID: 16685853.
      View in: PubMed
    162. Leung CW, Chiu WK. Clinical picture, diagnosis, treatment and outcome of severe acute respiratory syndrome (SARS) in children. Paediatr Respir Rev. 2004 Dec; 5(4):275-88. PMID: 15531251.
      View in: PubMed
    163. Schmid MF, Sherman MB, Matsudaira P, Chiu W. Structure of the acrosomal bundle. Nature. 2004 Sep 2; 431(7004):104-7. PMID: 15343340.
      View in: PubMed
    164. Chan CW, Chiu WK, Chan CC, Chow EY, Cheung HM, Ip PL. Osteonecrosis in children with severe acute respiratory syndrome. Pediatr Infect Dis J. 2004 Sep; 23(9):888-90. PMID: 15361738.
      View in: PubMed
    165. Booth CR, Jiang W, Baker ML, Zhou ZH, Ludtke SJ, Chiu W. A 9 angstroms single particle reconstruction from CCD captured images on a 200 kV electron cryomicroscope. J Struct Biol. 2004 Aug; 147(2):116-27. PMID: 15193640.
      View in: PubMed
    166. Mao Y, Vyas NK, Vyas MN, Chen DH, Ludtke SJ, Chiu W, Quiocho FA. Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer. EMBO J. 2004 Aug 4; 23(15):2963-71. PMID: 15272307; PMCID: PMC514939.
    167. Paredes AM, Ferreira D, Horton M, Saad A, Tsuruta H, Johnston R, Klimstra W, Ryman K, Hernandez R, Chiu W, Brown DT. Conformational changes in Sindbis virions resulting from exposure to low pH and interactions with cells suggest that cell penetration may occur at the cell surface in the absence of membrane fusion. Virology. 2004 Jul 1; 324(2):373-86. PMID: 15207623.
      View in: PubMed
    168. Ludtke SJ, Chen DH, Song JL, Chuang DT, Chiu W. Seeing GroEL at 6 A resolution by single particle electron cryomicroscopy. Structure. 2004 Jul; 12(7):1129-36. PMID: 15242589.
      View in: PubMed
    169. Chiu WS, McManus JF, Notini AJ, Cassady AI, Zajac JD, Davey RA. Transgenic mice that express Cre recombinase in osteoclasts. Genesis. 2004 Jul; 39(3):178-85. PMID: 15282744.
      View in: PubMed
    170. Ng PC, Leung CW, Chiu WK, Wong SF, Hon EK. SARS in newborns and children. Biol Neonate. 2004; 85(4):293-8. PMID: 15218286.
      View in: PubMed
    171. Chen C, Ko Y, Delannoy M, Ludtke SJ, Chiu W, Pedersen PL. Mitochondrial ATP synthasome: three-dimensional structure by electron microscopy of the ATP synthase in complex formation with carriers for Pi and ADP/ATP. J Biol Chem. 2004 Jul 23; 279(30):31761-8. PMID: 15166242.
      View in: PubMed
    172. Brink J, Ludtke SJ, Kong Y, Wakil SJ, Ma J, Chiu W. Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure. 2004 Feb; 12(2):185-91. PMID: 14962379.
      View in: PubMed
    173. Sherman MB, Orlova EV, Decker GL, Chiu W, Pownall HJ. Structure of triglyceride-rich human low-density lipoproteins according to cryoelectron microscopy. Biochemistry. 2003 Dec 23; 42(50):14988-93. PMID: 14674775.
      View in: PubMed
    174. Sherman MB, Chiu W. Electron beam coater for reduction of charging in ice-embedded biological specimens using Ti(88)Si(12) alloy. Microsc Microanal. 2003 Dec; 9(6):566-73. PMID: 14750991.
      View in: PubMed
    175. Ludtke SJ, Nason L, Tu H, Peng L, Chiu W. Object oriented database and electronic notebook for transmission electron microscopy. Microsc Microanal. 2003 Dec; 9(6):556-65. PMID: 14750990.
      View in: PubMed
    176. Lee S, Sowa ME, Watanabe YH, Sigler PB, Chiu W, Yoshida M, Tsai FT. The structure of ClpB: a molecular chaperone that rescues proteins from an aggregated state. Cell. 2003 Oct 17; 115(2):229-40. PMID: 14567920.
      View in: PubMed
    177. Ludtke SJ, Chiu W. Focal pair merging for contrast enhancement of single particles. J Struct Biol. 2003 Oct-Nov; 144(1-2):73-8. PMID: 14643210.
      View in: PubMed
    178. Jiang W, Baker ML, Wu Q, Bajaj C, Chiu W. Applications of a bilateral denoising filter in biological electron microscopy. J Struct Biol. 2003 Oct-Nov; 144(1-2):114-22. PMID: 14643214.
      View in: PubMed
    179. Baker ML, Jiang W, Bowman BR, Zhou ZH, Quiocho FA, Rixon FJ, Chiu W. Architecture of the herpes simplex virus major capsid protein derived from structural bioinformatics. J Mol Biol. 2003 Aug 8; 331(2):447-56. PMID: 12888351.
      View in: PubMed
    180. Chiu WK, Cheung PC, Ng KL, Ip PL, Sugunan VK, Luk DC, Ma LC, Chan BH, Lo KL, Lai WM. Severe acute respiratory syndrome in children: experience in a regional hospital in Hong Kong. Pediatr Crit Care Med. 2003 Jul; 4(3):279-83. PMID: 12831407.
      View in: PubMed
    181. Serysheva II, Bare DJ, Ludtke SJ, Kettlun CS, Chiu W, Mignery GA. Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy. J Biol Chem. 2003 Jun 13; 278(24):21319-22. PMID: 12714606.
      View in: PubMed
    182. Bowman BR, Baker ML, Rixon FJ, Chiu W, Quiocho FA. Structure of the herpesvirus major capsid protein. EMBO J. 2003 Feb 17; 22(4):757-65. PMID: 12574112; PMCID: PMC145446.
    183. Jiang W, Li Z, Zhang Z, Baker ML, Prevelige PE, Chiu W. Coat protein fold and maturation transition of bacteriophage P22 seen at subnanometer resolutions. Nat Struct Biol. 2003 Feb; 10(2):131-5. PMID: 12536205.
      View in: PubMed
    184. Ko YH, Delannoy M, Hullihen J, Chiu W, Pedersen PL. Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP. J Biol Chem. 2003 Apr 4; 278(14):12305-9. PMID: 12560333.
      View in: PubMed
    185. Paredes A, Alwell-Warda K, Weaver SC, Chiu W, Watowich SJ. Structure of isolated nucleocapsids from venezuelan equine encephalitis virus and implications for assembly and disassembly of enveloped virus. J Virol. 2003 Jan; 77(1):659-64. PMID: 12477868; PMCID: PMC140571.
    186. Zhou ZH, Chiu W. Determination of icosahedral virus structures by electron cryomicroscopy at subnanometer resolution. Adv Protein Chem. 2003; 64:93-124. PMID: 13677046.
      View in: PubMed
    187. Chiu W, Johnson JE. Virus structure. Preface. Adv Protein Chem. 2003; 64:xi-xii. PMID: 13677043.
      View in: PubMed
    188. Ju T, Warren J, Eichele G, Thaller C, Chiu W, Carson J. A geometric database for gene expression data. Symp Geom Process. 2003; 2003:166-176. PMID: 20631855.
      View in: PubMed
    189. Rixon FJ, Chiu W. Studying large viruses. Adv Protein Chem. 2003; 64:379-408. PMID: 13677054.
      View in: PubMed
    190. Baker ML, Serysheva II, Sencer S, Wu Y, Ludtke SJ, Jiang W, Hamilton SL, Chiu W. The skeletal muscle Ca2+ release channel has an oxidoreductase-like domain. Proc Natl Acad Sci U S A. 2002 Sep 17; 99(19):12155-60. PMID: 12218169; PMCID: PMC129414.
    191. Serysheva II, Ludtke SJ, Baker MR, Chiu W, Hamilton SL. Structure of the voltage-gated L-type Ca2+ channel by electron cryomicroscopy. Proc Natl Acad Sci U S A. 2002 Aug 6; 99(16):10370-5. PMID: 12149473; PMCID: PMC124921.
    192. Rockel B, Jakana J, Chiu W, Baumeister W. Electron cryo-microscopy of VAT, the archaeal p97/CDC48 homologue from Thermoplasma acidophilum. J Mol Biol. 2002 Apr 12; 317(5):673-81. PMID: 11955016.
      View in: PubMed
    193. Chiu W, Baker ML, Jiang W, Zhou ZH. Deriving folds of macromolecular complexes through electron cryomicroscopy and bioinformatics approaches. Curr Opin Struct Biol. 2002 Apr; 12(2):263-9. PMID: 11959506.
      View in: PubMed
    194. Yotnda P, Chen DH, Chiu W, Piedra PA, Davis A, Templeton NS, Brenner MK. Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses. Mol Ther. 2002 Mar; 5(3):233-41. PMID: 11863412.
      View in: PubMed
    195. Chiu W, Rixon FJ. High resolution structural studies of complex icosahedral viruses: a brief overview. Virus Res. 2002 Jan 30; 82(1-2):9-17. PMID: 11885957.
      View in: PubMed
    196. Brink J, Ludtke SJ, Yang CY, Gu ZW, Wakil SJ, Chiu W. Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proc Natl Acad Sci U S A. 2002 Jan 8; 99(1):138-43. PMID: 11756679; PMCID: PMC117528.
    197. Chen DH, Jakana J, McNab D, Mitchell J, Zhou ZH, Dougherty M, Chiu W, Rixon FJ. The pattern of tegument-capsid interaction in the herpes simplex virus type 1 virion is not influenced by the small hexon-associated protein VP26. J Virol. 2001 Dec; 75(23):11863-7. PMID: 11689667; PMCID: PMC114772.
    198. Jiang W, Li Z, Zhang Z, Booth CR, Baker ML, Chiu W. Semi-automated icosahedral particle reconstruction at sub-nanometer resolution. J Struct Biol. 2001 Dec; 136(3):214-25. PMID: 12051901.
      View in: PubMed
    199. Ludtke SJ, Jakana J, Song JL, Chuang DT, Chiu W. A 11.5 A single particle reconstruction of GroEL using EMAN. J Mol Biol. 2001 Nov 23; 314(2):253-62. PMID: 11718559.
      View in: PubMed
    200. Paredes A, Alwell-Warda K, Weaver SC, Chiu W, Watowich SJ. Venezuelan equine encephalomyelitis virus structure and its divergence from old world alphaviruses. J Virol. 2001 Oct; 75(19):9532-7. PMID: 11533216; PMCID: PMC114521.
    201. Jiang W, Chiu W. Web-based Simulation for Contrast Transfer Function and Envelope Functions. Microsc Microanal. 2001 Jul; 7(4):329-334. PMID: 12597807.
      View in: PubMed
    202. He J, Schmid MF, Zhou ZH, Rixon F, Chiu W. Finding and using local symmetry in identifying lower domain movements in hexon subunits of the herpes simplex virus type 1 B capsid. J Mol Biol. 2001 Jun 15; 309(4):903-14. PMID: 11399067.
      View in: PubMed
    203. Jiang W, Baker ML, Ludtke SJ, Chiu W. Bridging the information gap: computational tools for intermediate resolution structure interpretation. J Mol Biol. 2001 May 18; 308(5):1033-44. PMID: 11352589.
      View in: PubMed
    204. Saad A, Ludtke SJ, Jakana J, Rixon FJ, Tsuruta H, Chiu W. Fourier amplitude decay of electron cryomicroscopic images of single particles and effects on structure determination. J Struct Biol. 2001 Jan; 133(1):32-42. PMID: 11356062.
      View in: PubMed
    205. Thuman-Commike PA, Chiu W. Reconstruction principles of icosahedral virus structure determination using electron cryomicroscopy. Micron. 2000 Dec; 31(6):687-711. PMID: 10838029.
      View in: PubMed
    206. Huang HM, Lee MC, Lee SY, Chiu WT, Pan LC, Chen CT. Finite element analysis of brain contusion: an indirect impact study. Med Biol Eng Comput. 2000 May; 38(3):253-9. PMID: 10912340.
      View in: PubMed
    207. Zhang Z, Greene B, Thuman-Commike PA, Jakana J, Prevelige PE, King J, Chiu W. Visualization of the maturation transition in bacteriophage P22 by electron cryomicroscopy. J Mol Biol. 2000 Mar 31; 297(3):615-26. PMID: 10731416.
      View in: PubMed
    208. Schmid MF, Sherman MB, Matsudaira P, Tsuruta H, Chiu W. Scaling structure factor amplitudes in electron cryomicroscopy using X-Ray solution scattering. J Struct Biol. 1999 Dec 1; 128(1):51-7. PMID: 10600558.
      View in: PubMed
    209. Sherman MB, Jakana J, Sun S, Matsudaira P, Chiu W, Schmid MF. The three-dimensional structure of the Limulus acrosomal process: a dynamic actin bundle. J Mol Biol. 1999 Nov 19; 294(1):139-49. PMID: 10556034.
      View in: PubMed
    210. Chen M, Shih JC, Chiu WT, Hsieh FJ. Separation of cesarean scar during second-trimester intravaginal misoprostol abortion. Obstet Gynecol. 1999 Nov; 94(5 Pt 2):840. PMID: 10546751.
      View in: PubMed
    211. Serysheva II, Schatz M, van Heel M, Chiu W, Hamilton SL. Structure of the skeletal muscle calcium release channel activated with Ca2+ and AMP-PCP. Biophys J. 1999 Oct; 77(4):1936-44. PMID: 10512814; PMCID: PMC1300475.
    212. Huang HM, Lee MC, Chiu WT, Chen CT, Lee SY. Three-dimensional finite element analysis of subdural hematoma. J Trauma. 1999 Sep; 47(3):538-44. PMID: 10498311.
      View in: PubMed
    213. McGough A, Chiu W. ADF/cofilin weakens lateral contacts in the actin filament. J Mol Biol. 1999 Aug 20; 291(3):513-9. PMID: 10448032.
      View in: PubMed
    214. Saad A, Zhou ZH, Jakana J, Chiu W, Rixon FJ. Roles of triplex and scaffolding proteins in herpes simplex virus type 1 capsid formation suggested by structures of recombinant particles. J Virol. 1999 Aug; 73(8):6821-30. PMID: 10400780; PMCID: PMC112767.
    215. Orlova EV, Sherman MB, Chiu W, Mowri H, Smith LC, Gotto AM. Three-dimensional structure of low density lipoproteins by electron cryomicroscopy. Proc Natl Acad Sci U S A. 1999 Jul 20; 96(15):8420-5. PMID: 10411890; PMCID: PMC17531.
    216. Chiu WT, Chan P, Liao SS, Liou JR, Cheng JT. Effect of trilinolein on the activity and gene expression of superoxide dismutase in cultured rat brain astrocytes. Neurosci Lett. 1999 Jul 2; 269(1):17-20. PMID: 10821634.
      View in: PubMed
    217. Thuman-Commike PA, Greene B, Malinski JA, Burbea M, McGough A, Chiu W, Prevelige PE. Mechanism of scaffolding-directed virus assembly suggested by comparison of scaffolding-containing and scaffolding-lacking P22 procapsids. Biophys J. 1999 Jun; 76(6):3267-77. PMID: 10354452; PMCID: PMC1300296.
    218. Tsauo JY, Hwang JS, Chiu WT, Hung CC, Wang JD. Estimation of expected utility gained from the helmet law in Taiwan by quality-adjusted survival time. Accid Anal Prev. 1999 May; 31(3):253-63. PMID: 10196602.
      View in: PubMed
    219. Thuman-Commike PA, Tsuruta H, Greene B, Prevelige PE, King J, Chiu W. Solution x-ray scattering-based estimation of electron cryomicroscopy imaging parameters for reconstruction of virus particles. Biophys J. 1999 Apr; 76(4):2249-61. PMID: 10096920; PMCID: PMC1300198.
    220. Chiu W, McGough A, Sherman MB, Schmid MF. High-resolution electron cryomicroscopy of macromolecular assemblies. Trends Cell Biol. 1999 Apr; 9(4):154-9. PMID: 10203794.
      View in: PubMed
    221. Sherman MB, Soejima T, Chiu W, van Heel M. Multivariate analysis of single unit cells in electron crystallography. Ultramicroscopy. 1998 Sep; 74(4):179-99. PMID: 9809457.
      View in: PubMed
    222. Brink J, Gross H, Tittmann P, Sherman MB, Chiu W. Reduction of charging in protein electron cryomicroscopy. J Microsc. 1998 Jul; 191(Pt 1):67-73. PMID: 9723190.
      View in: PubMed
    223. Brink J, Sherman MB, Berriman J, Chiu W. Evaluation of charging on macromolecules in electron cryomicroscopy. Ultramicroscopy. 1998 Apr; 72(1-2):41-52. PMID: 9561796.
      View in: PubMed
    224. McGough A, Chiu W, Way M. Determination of the gelsolin binding site on F-actin: implications for severing and capping. Biophys J. 1998 Feb; 74(2 Pt 1):764-72. PMID: 9533689; PMCID: PMC1302557.
    225. Paredes AM, Heidner H, Thuman-Commike P, Prasad BV, Johnston RE, Chiu W. Structural localization of the E3 glycoprotein in attenuated Sindbis virus mutants. J Virol. 1998 Feb; 72(2):1534-41. PMID: 9445057; PMCID: PMC124635.
    226. Zhou ZH, Chiu W, Haskell K, Spears H, Jakana J, Rixon FJ, Scott LR. Refinement of herpesvirus B-capsid structure on parallel supercomputers. Biophys J. 1998 Jan; 74(1):576-88. PMID: 9449358; PMCID: PMC1299410.
    227. Sherman MB, Jakana J, Sun S, Matsudaira P, Chiu W, Schmid MF. A strategy for electron tomographic data collection and crystallographic reconstruction of biological bundles. J Struct Biol. 1997 Dec; 120(3):245-56. PMID: 9441930.
      View in: PubMed
    228. Sherman MB, Chiu W. Reliability of phases retrieved from 400-kV spot-scan images of purple membranes acquired on a slow-scan CCD camera. J Microsc. 1997 Dec; 188(Pt 3):285-9. PMID: 9450331.
      View in: PubMed
    229. Chen HY, Chiu WT, Chen SS, Lee LS, Hung CI, Hung CL, Wang YC, Hung CC, Lin LS, Shih YH. A nationwide epidemiological study of spinal cord injuries in Taiwan from July 1992 to June 1996. Neurol Res. 1997 Dec; 19(6):617-22. PMID: 9427963.
      View in: PubMed
    230. McGough A, Pope B, Chiu W, Weeds A. Cofilin changes the twist of F-actin: implications for actin filament dynamics and cellular function. J Cell Biol. 1997 Aug 25; 138(4):771-81. PMID: 9265645; PMCID: PMC2138052.
    231. McAlarney ME, Chiu WK. Comparison of numeric techniques in the analysis of cleft palate dental arch form change. Cleft Palate Craniofac J. 1997 Jul; 34(4):281-91. PMID: 9257018.
      View in: PubMed
    232. Chiu W, Avila-Sakar AJ, Schmid MF. Electron crystallography of macromolecular periodic arrays on phospholipid monolayers. Adv Biophys. 1997; 34:161-72. PMID: 9204133.
      View in: PubMed
    233. Chen HY, Chen SS, Chiu WT, Lee LS, Hung CI, Hung CL, Wang YC, Hung CC, Lin LS, Shih YH, Kuo CY. A nationwide epidemiological study of spinal cord injury in geriatric patients in Taiwan. Neuroepidemiology. 1997; 16(5):241-7. PMID: 9346344.
      View in: PubMed
    234. Prasad BV, Rothnagel R, Zeng CQ, Jakana J, Lawton JA, Chiu W, Estes MK. Visualization of ordered genomic RNA and localization of transcriptional complexes in rotavirus. Nature. 1996 Aug 1; 382(6590):471-3. PMID: 8684490.
      View in: PubMed
    235. Thuman-Commike PA, Greene B, Jakana J, Prasad BV, King J, Prevelige PE, Chiu W. Three-dimensional structure of scaffolding-containing phage p22 procapsids by electron cryo-microscopy. J Mol Biol. 1996 Jul 5; 260(1):85-98. PMID: 8676394.
      View in: PubMed
    236. Orlova EV, Serysheva II, van Heel M, Hamilton SL, Chiu W. Two structural configurations of the skeletal muscle calcium release channel. Nat Struct Biol. 1996 Jun; 3(6):547-52. PMID: 8646541.
      View in: PubMed
    237. Sherman MB, Brink J, Chiu W. Performance of a slow-scan CCD camera for macromolecular imaging in a 400 kV electron cryomicroscope. Micron. 1996 Apr; 27(2):129-39. PMID: 8858867.
      View in: PubMed
    238. Chang Z, Primm TP, Jakana J, Lee IH, Serysheva I, Chiu W, Gilbert HF, Quiocho FA. Mycobacterium tuberculosis 16-kDa antigen (Hsp16.3) functions as an oligomeric structure in vitro to suppress thermal aggregation. J Biol Chem. 1996 Mar 22; 271(12):7218-23. PMID: 8636160.
      View in: PubMed
    239. Chiu WT, Chen SY, Lin JW, Gan YH, Chiang MZ, Tseng CH, Chen JG. Color-Doppler Ultrasound-assisted endoscopic neurosurgery for intracerebral hemorrhage. Zhonghua Yi Xue Za Zhi (Taipei). 1996 Mar; 57(3):198-203. PMID: 8935226.
      View in: PubMed
    240. Avila-Sakar AJ, Chiu W. Visualization of beta-sheets and side-chain clusters in two-dimensional periodic arrays of streptavidin on phospholipid monolayers by electron crystallography. Biophys J. 1996 Jan; 70(1):57-68. PMID: 8770187; PMCID: PMC1224909.
    241. Thuman-Commike PA, Chiu W. PTOOL: a software package for the selection of particles from electron cryomicroscopy spot-scan images. J Struct Biol. 1996 Jan-Feb; 116(1):41-7. PMID: 8742721.
      View in: PubMed
    242. Zhou ZH, Hardt S, Wang B, Sherman MB, Jakana J, Chiu W. CTF determination of images of ice-embedded single particles using a graphics interface. J Struct Biol. 1996 Jan-Feb; 116(1):216-22. PMID: 8742746.
      View in: PubMed
    243. Zhou ZH, He J, Jakana J, Tatman JD, Rixon FJ, Chiu W. Assembly of VP26 in herpes simplex virus-1 inferred from structures of wild-type and recombinant capsids. Nat Struct Biol. 1995 Nov; 2(11):1026-30. PMID: 7583656.
      View in: PubMed
    244. Schmid MF, Jakana J, Chiu W, Matsudaira P. A 7-A projection map of frozen, hydrated acrosomal bundle from Limulus sperm. J Struct Biol. 1995 Sep-Oct; 115(2):209-13. PMID: 7577241.
      View in: PubMed
    245. Schmid MF, Jakana J, Matsudaira P, Chiu W. Three-dimensional structure of the acrosomal filament of Limulus sperm by 400 kV electron cryomicroscopy. Biophys J. 1995 Apr; 68(4 Suppl):8S-11S. PMID: 7787112; PMCID: PMC1281851.
    246. Serysheva II, Orlova EV, Chiu W, Sherman MB, Hamilton SL, van Heel M. Electron cryomicroscopy and angular reconstitution used to visualize the skeletal muscle calcium release channel. Nat Struct Biol. 1995 Jan; 2(1):18-24. PMID: 7719847.
      View in: PubMed
    247. Zhou ZH, Prasad BV, Jakana J, Rixon FJ, Chiu W. Protein subunit structures in the herpes simplex virus A-capsid determined from 400 kV spot-scan electron cryomicroscopy. J Mol Biol. 1994 Sep 30; 242(4):456-69. PMID: 7932703.
      View in: PubMed
    248. Brink J, Chiu W. Applications of a slow-scan CCD camera in protein electron crystallography. J Struct Biol. 1994 Jul-Aug; 113(1):23-34. PMID: 7880650.
      View in: PubMed
    249. Avila-Sakar AJ, Guan TL, Arad T, Schmid MF, Loke TW, Yonath A, Piefke J, Franceschi F, Chiu W. Electron cryomicroscopy of Bacillus stearothermophilus 50 S ribosomal subunits crystallized on phospholipid monolayers. J Mol Biol. 1994 Jun 24; 239(5):689-97. PMID: 8014989.
      View in: PubMed
    250. Schmid MF, Agris JM, Jakana J, Matsudaira P, Chiu W. Three-dimensional structure of a single filament in the Limulus acrosomal bundle: scruin binds to homologous helix-loop-beta motifs in actin. J Cell Biol. 1994 Feb; 124(3):341-50. PMID: 8294517; PMCID: PMC2119938.
    251. Schmid MF, Prasad BV, Chiu W. Structural studies of viruses by electron cryomicroscopy. Arch Virol Suppl. 1994; 9:523-9. PMID: 8032281.
      View in: PubMed
    252. Prasad BV, Chiu W. Structure of rotavirus. Curr Top Microbiol Immunol. 1994; 185:9-29. PMID: 8050286.
      View in: PubMed
    253. Shaw AL, Rothnagel R, Chen D, Ramig RF, Chiu W, Prasad BV. Three-dimensional visualization of the rotavirus hemagglutinin structure. Cell. 1993 Aug 27; 74(4):693-701. PMID: 8395350.
      View in: PubMed
    254. Chiu W, Schmid MF. Electron crystallography of macromolecules. Curr Opin Biotechnol. 1993 Aug; 4(4):397-402. PMID: 7763969.
      View in: PubMed
    255. Soejima T, Sherman MB, Schmid MF, Chiu W. 4-A projection map of bacteriophage T4 DNA helix-destabilizing protein (gp32*I) crystal by 400-kV electron cryomicroscopy. J Struct Biol. 1993 Jul-Aug; 111(1):9-16. PMID: 8251266.
      View in: PubMed
    256. Prasad BV, Prevelige PE, Marietta E, Chen RO, Thomas D, King J, Chiu W. Three-dimensional transformation of capsids associated with genome packaging in a bacterial virus. J Mol Biol. 1993 May 5; 231(1):65-74. PMID: 8496966.
      View in: PubMed
    257. Chiu W, Schmid MF, Prasad BV. Teaching electron diffraction and imaging of macromolecules. Biophys J. 1993 May; 64(5):1610-25. PMID: 8324196; PMCID: PMC1262489.
    258. Schmid MF, Jakana J, Matsudaira P, Chiu W. Imaging frozen, hydrated acrosomal bundle from Limulus sperm at 7 A resolution with a 400 kV electron cryomicroscope. J Mol Biol. 1993 Mar 20; 230(2):384-6. PMID: 8464053.
      View in: PubMed
    259. Zhou ZH, Chiu W. Prospects for using an IVEM with a FEG for imaging macromolecules towards atomic resolution. Ultramicroscopy. 1993 Feb; 49(1-4):407-16. PMID: 8475604.
      View in: PubMed
    260. Avila-Sakar AJ, Schmid MF, Li LS, Whitby FG, Phillips GN, Chiu W. Preliminary electron crystallographic analysis of ice-embedded tropomyosin crystals. J Struct Biol. 1993 Jan-Feb; 110(1):67-74. PMID: 8494673.
      View in: PubMed
    261. Chiu W. What does electron cryomicroscopy provide that X-ray crystallography and NMR spectroscopy cannot? Annu Rev Biophys Biomol Struct. 1993; 22:233-55. PMID: 8347990.
      View in: PubMed
    262. Brink J, Chiu W, Dougherty M. Computer-controlled spot-scan imaging of crotoxin complex crystals with 400 keV electrons at near-atomic resolution. Ultramicroscopy. 1992 Oct; 46(1-4):229-40. PMID: 1481273.
      View in: PubMed
    263. Lee LS, Shih YH, Chiu WT, Lin LS, Wu CM, Wang YC, Huang JS, Hung CC, Shih CJ, Laporte RE. [Epidemiologic study of head injuries in Taipei City, Taiwan]. Zhonghua Yi Xue Za Zhi (Taipei). 1992 Sep; 50(3):219-25. PMID: 1330249.
      View in: PubMed
    264. Schmid MF, Jakana J, Matsudaira P, Chiu W. Effects of radiation damage with 400-kV electrons on frozen, hydrated actin bundles. J Struct Biol. 1992 Jan-Feb; 108(1):62-8. PMID: 1562434.
      View in: PubMed
    265. Schmid MF, Matsudaira P, Jeng TW, Jakana J, Towns-Andrews E, Bordas J, Chiu W. Crystallographic analysis of acrosomal bundle from Limulus sperm. J Mol Biol. 1991 Sep 20; 221(2):711-25. PMID: 1920441.
      View in: PubMed
    266. Brink J, Chiu W. Contrast analysis of cryo-images of n-paraffin recorded at 400 kV out to 2.1 A resolution. J Microsc. 1991 Feb; 161(Pt 2):279-95. PMID: 2038034.
      View in: PubMed
    267. Prasad BV, Degn LL, Jeng TW, Chiu W. Estimation of allowable errors for tilt parameter determination in protein electron crystallography. Ultramicroscopy. 1990 Oct; 33(4):281-5. PMID: 2260229.
      View in: PubMed
    268. Prasad BV, Burns JW, Marietta E, Estes MK, Chiu W. Localization of VP4 neutralization sites in rotavirus by three-dimensional cryo-electron microscopy. Nature. 1990 Feb 1; 343(6257):476-9. PMID: 2153941.
      View in: PubMed
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