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RAY-CHANG WU

TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
Address1 Baylor Plaza
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wu RC, Zeng Y, Pan IW, Wu MY. Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis. Mol Endocrinol. 2015 Sep; 29(9):1334-46. PMID: 26258622.
      View in: PubMed
    2. Wang W, Bian K, Vallabhaneni S, Zhang B, Wu RC, O'Malley BW, Long W. ERK3 promotes endothelial cell functions by upregulating SRC-3/SP1-mediated VEGFR2 expression. J Cell Physiol. 2014 Oct; 229(10):1529-37. PMID: 24585635; PMCID: PMC4078721.
    3. Yi P, Xia W, Wu RC, Lonard DM, Hung MC, O'Malley BW. SRC-3 coactivator regulates cell resistance to cytotoxic stress via TRAF4-mediated p53 destabilization. Genes Dev. 2013 Feb 1; 27(3):274-87. PMID: 23388826; PMCID: PMC3576513.
    4. York B, Yu C, Sagen JV, Liu Z, Nikolai BC, Wu RC, Finegold M, Xu J, O'Malley BW. Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology. Proc Natl Acad Sci U S A. 2010 Jun 15; 107(24):11122-7. PMID: 20534466; PMCID: PMC2890746.
    5. Xu J, Wu RC, O'Malley BW. Normal and cancer-related functions of the p160 steroid receptor co-activator (SRC) family. Nat Rev Cancer. 2009 Sep; 9(9):615-30. PMID: 19701241; PMCID: PMC2908510.
    6. Yuan Y, Qin L, Liu D, Wu RC, Mussi P, Zhou S, Songyang Z, Xu J. Genetic screening reveals an essential role of p27kip1 in restriction of breast cancer progression. Cancer Res. 2007 Sep 1; 67(17):8032-42. PMID: 17804714; PMCID: PMC2412956.
    7. Amazit L, Pasini L, Szafran AT, Berno V, Wu RC, Mielke M, Jones ED, Mancini MG, Hinojos CA, O'Malley BW, Mancini MA. Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation. Mol Cell Biol. 2007 Oct; 27(19):6913-32. PMID: 17646391; PMCID: PMC2099228.
    8. Wu RC, Feng Q, Lonard DM, O'Malley BW. SRC-3 coactivator functional lifetime is regulated by a phospho-dependent ubiquitin time clock. Cell. 2007 Jun 15; 129(6):1125-40. PMID: 17574025.
      View in: PubMed
    9. Li C, Wu RC, Amazit L, Tsai SY, Tsai MJ, O'Malley BW. Specific amino acid residues in the basic helix-loop-helix domain of SRC-3 are essential for its nuclear localization and proteasome-dependent turnover. Mol Cell Biol. 2007 Feb; 27(4):1296-308. PMID: 17158932; PMCID: PMC1800725.
    10. Louet JF, Coste A, Amazit L, Tannour-Louet M, Wu RC, Tsai SY, Tsai MJ, Auwerx J, O'Malley BW. Oncogenic steroid receptor coactivator-3 is a key regulator of the white adipogenic program. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17868-73. PMID: 17098861; PMCID: PMC1693839.
    11. Tanaka T, Nishimura D, Wu RC, Amano M, Iso T, Kedes L, Nishida H, Kaibuchi K, Hamamori Y. Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase. J Biol Chem. 2006 Jun 2; 281(22):15320-9. PMID: 16574662.
      View in: PubMed
    12. Yi P, Wu RC, Sandquist J, Wong J, Tsai SY, Tsai MJ, Means AR, O'Malley BW. Peptidyl-prolyl isomerase 1 (Pin1) serves as a coactivator of steroid receptor by regulating the activity of phosphorylated steroid receptor coactivator 3 (SRC-3/AIB1). Mol Cell Biol. 2005 Nov; 25(21):9687-99. PMID: 16227615; PMCID: PMC1265806.
    13. Wu RC, Smith CL, O'Malley BW. Transcriptional regulation by steroid receptor coactivator phosphorylation. Endocr Rev. 2005 May; 26(3):393-9. PMID: 15814849.
      View in: PubMed
    14. Wu RC, Qin J, Yi P, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Selective phosphorylations of the SRC-3/AIB1 coactivator integrate genomic reponses to multiple cellular signaling pathways. Mol Cell. 2004 Sep 24; 15(6):937-49. PMID: 15383283.
      View in: PubMed
    15. Wu RC, Blumenthal M, Li X, Schönthal AH. Loss of cellular adhesion to matrix induces p53-independent expression of PTEN tumor suppressor. BMC Mol Biol. 2002 Jul 12; 3:11. PMID: 12113656; PMCID: PMC117602.
    16. Wu RC, Qin J, Hashimoto Y, Wong J, Xu J, Tsai SY, Tsai MJ, O'Malley BW. Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. Mol Cell Biol. 2002 May; 22(10):3549-61. PMID: 11971985; PMCID: PMC133790.
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