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JEFFREY L NOEBELS

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neurology
DivisionNeurology
AddressOne Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Human Genetics
    DivisionMolecular & Human Genetics

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience
    DivisionNeuroscience


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lam AD, Deck G, Goldman A, Eskandar EN, Noebels J, Cole AJ. Silent hippocampal seizures and spikes identified by foramen ovale electrodes in Alzheimer's disease. Nat Med. 2017 May 01. PMID: 28459436.
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    2. John Lin CC, Yu K, Hatcher A, Huang TW, Lee HK, Carlson J, Weston MC, Chen F, Zhang Y, Zhu W, Mohila CA, Ahmed N, Patel AJ, Arenkiel BR, Noebels JL, Creighton CJ, Deneen B. Identification of diverse astrocyte populations and their malignant analogs. Nat Neurosci. 2017 Feb 06. PMID: 28166219.
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    3. Tang M, Gao G, Rueda CB, Yu H, Thibodeaux DN, Awano T, Engelstad KM, Sanchez-Quintero MJ, Yang H, Li F, Li H, Su Q, Shetler KE, Jones L, Seo R, McConathy J, Hillman EM, Noebels JL, De Vivo DC, Monani UR. Brain microvasculature defects and Glut1 deficiency syndrome averted by early repletion of the glucose transporter-1 protein. Nat Commun. 2017 Jan 20; 8:14152. PMID: 28106060.
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    4. Lopez AY, Wang X, Xu M, Maheshwari A, Curry D, Lam S, Adesina AM, Noebels JL, Sun QQ, Cooper EC. Ankyrin-G isoform imbalance and interneuronopathy link epilepsy and bipolar disorder. Mol Psychiatry. 2016 Dec 13. PMID: 27956739.
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    5. Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Correction: Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. PLoS One. 2016; 11(11):e0167264. PMID: 27870904.
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    6. Aiba I, Wehrens XH, Noebels JL. Leaky RyR2 channels unleash a brainstem spreading depolarization mechanism of sudden cardiac death. Proc Natl Acad Sci U S A. 2016 Aug 16; 113(33):E4895-903. PMID: 27482086.
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    7. Holmes GL, Noebels JL. The Epilepsy Spectrum: Targeting Future Research Challenges. Cold Spring Harb Perspect Med. 2016; 6(7). PMID: 27371672.
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    8. Noebels J. Hippocampal abnormalities and sudden childhood death. Forensic Sci Med Pathol. 2016 Jun; 12(2):198-9. PMID: 27094436.
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    9. Horváth A, Sz?cs A, Barcs G, Noebels JL, Kamondi A. Epileptic Seizures in Alzheimer Disease: A Review. Alzheimer Dis Assoc Disord. 2016 Apr-Jun; 30(2):186-92. PMID: 26756385.
      View in: PubMed
    10. Bomben VC, Aiba I, Qian J, Mark MD, Herlitze S, Noebels JL. Isolated P/Q Calcium Channel Deletion in Layer VI Corticothalamic Neurons Generates Absence Epilepsy. J Neurosci. 2016 Jan 13; 36(2):405-18. PMID: 26758833.
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    11. Maheshwari A, Marks RL, Yu KM, Noebels JL. Shift in interictal relative gamma power as a novel biomarker for drug response in two mouse models of absence epilepsy. Epilepsia. 2016 Jan; 57(1):79-88. PMID: 26663261.
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    12. Noebels JL. Single-Gene Determinants of Epilepsy Comorbidity. Cold Spring Harb Perspect Med. 2015 Nov; 5(11). PMID: 26525453.
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    13. Siehr MS, Noebels JL. Early rescue of interneuron disease trajectory in developmental epilepsies. Curr Opin Neurobiol. 2016 Feb; 36:82-8. PMID: 26517286; PMCID: PMC4738159 [Available on 02/01/17].
    14. Lhatoo S, Noebels J, Whittemore V. Sudden unexpected death in epilepsy: Identifying risk and preventing mortality. Epilepsia. 2015 Nov; 56(11):1700-6. PMID: 26494436.
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    15. Kole MJ, Qian J, Waase MP, Klassen TL, Chen TT, Augustine GJ, Noebels JL. Selective Loss of Presynaptic Potassium Channel Clusters at the Cerebellar Basket Cell Terminal Pinceau in Adam11 Mutants Reveals Their Role in Ephaptic Control of Purkinje Cell Firing. J Neurosci. 2015 Aug 12; 35(32):11433-44. PMID: 26269648.
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    16. Glasscock E, Voigt N, McCauley MD, Sun Q, Li N, Chiang DY, Zhou XB, Molina CE, Thomas D, Schmidt C, Skapura DG, Noebels JL, Dobrev D, Wehrens XH. Expression and function of Kv1.1 potassium channels in human atria from patients with atrial fibrillation. Basic Res Cardiol. 2015 Sep; 110(5):505. PMID: 26162324.
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    17. Aiba I, Noebels JL. Spreading depolarization in the brainstem mediates sudden cardiorespiratory arrest in mouse SUDEP models. Sci Transl Med. 2015 Apr 8; 7(282):282ra46. PMID: 25855492; PMCID: PMC4852131.
    18. Noebels J. Pathway-driven discovery of epilepsy genes. Nat Neurosci. 2015 Mar; 18(3):344-50. PMID: 25710836; PMCID: PMC4852130.
    19. Nakao A, Miki T, Shimono K, Oka H, Numata T, Kiyonaka S, Matsushita K, Ogura H, Niidome T, Noebels JL, Wakamori M, Imoto K, Mori Y. Compromised maturation of GABAergic inhibition underlies abnormal network activity in the hippocampus of epileptic Ca2+ channel mutant mice, tottering. Pflugers Arch. 2015 Apr; 467(4):737-52. PMID: 24947601.
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    20. Ozkan ED, Creson TK, Kramár EA, Rojas C, Seese RR, Babyan AH, Shi Y, Lucero R, Xu X, Noebels JL, Miller CA, Lynch G, Rumbaugh G. Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons. Neuron. 2014 Jun 18; 82(6):1317-33. PMID: 24945774; PMCID: PMC4104574.
    21. Bomben V, Holth J, Reed J, Cramer P, Landreth G, Noebels J. Bexarotene reduces network excitability in models of Alzheimer's disease and epilepsy. Neurobiol Aging. 2014 Sep; 35(9):2091-5. PMID: 24767949; PMCID: PMC4053509.
    22. Born HA, Kim JY, Savjani RR, Das P, Dabaghian YA, Guo Q, Yoo JW, Schuler DR, Cirrito JR, Zheng H, Golde TE, Noebels JL, Jankowsky JL. Genetic suppression of transgenic APP rescues Hypersynchronous network activity in a mouse model of Alzeimer's disease. J Neurosci. 2014 Mar 12; 34(11):3826-40. PMID: 24623762; PMCID: PMC3951689.
    23. Olivetti PR, Maheshwari A, Noebels JL. Neonatal estradiol stimulation prevents epilepsy in Arx model of X-linked infantile spasms syndrome. Sci Transl Med. 2014 Jan 22; 6(220):220ra12. PMID: 24452264; PMCID: PMC4034383.
    24. Guerrini R, Noebels J. How can advances in epilepsy genetics lead to better treatments and cures? Adv Exp Med Biol. 2014; 813:309-17. PMID: 25012387.
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    25. Maheshwari A, Noebels JL. Monogenic models of absence epilepsy: windows into the complex balance between inhibition and excitation in thalamocortical microcircuits. Prog Brain Res. 2014; 213:223-52. PMID: 25194492.
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    26. Klassen TL, Bomben VC, Patel A, Drabek J, Chen TT, Gu W, Zhang F, Chapman K, Lupski JR, Noebels JL, Goldman AM. High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile. Epilepsia. 2014 Feb; 55(2):e6-12. PMID: 24372310; PMCID: PMC4195652.
    27. Maheshwari A, Nahm WK, Noebels JL. Paradoxical proepileptic response to NMDA receptor blockade linked to cortical interneuron defect in stargazer mice. Front Cell Neurosci. 2013; 7:156. PMID: 24065886; PMCID: PMC3776135.
    28. Wilcox KS, Dixon-Salazar T, Sills GJ, Ben-Menachem E, White HS, Porter RJ, Dichter MA, Moshé SL, Noebels JL, Privitera MD, Rogawski MA. Issues related to development of new antiseizure treatments. Epilepsia. 2013 Aug; 54 Suppl 4:24-34. PMID: 23909851; PMCID: PMC3947404.
    29. Cole AJ, Eskandar E, Mela T, Noebels JL, Gonzalez RG, McGuone D. Case records of the Massachusetts General Hospital. Case 18-2013: a 32-year-old woman with recurrent episodes of altered consciousness. N Engl J Med. 2013 Jun 13; 368(24):2304-12. PMID: 23758236.
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    30. Maejima T, Wollenweber P, Teusner LU, Noebels JL, Herlitze S, Mark MD. Postnatal loss of P/Q-type channels confined to rhombic-lip-derived neurons alters synaptic transmission at the parallel fiber to purkinje cell synapse and replicates genomic Cacna1a mutation phenotype of ataxia and seizures in mice. J Neurosci. 2013 Mar 20; 33(12):5162-74. PMID: 23516282; PMCID: PMC3641643.
    31. Klassen TL, Drabek J, Tomson T, Sveinsson O, von Döbeln U, Noebels JL, Goldman AM. Visual automated fluorescence electrophoresis provides simultaneous quality, quantity, and molecular weight spectra for genomic DNA from archived neonatal blood spots. J Mol Diagn. 2013 May; 15(3):283-90. PMID: 23518217; PMCID: PMC3644733.
    32. Chen TT, Klassen TL, Goldman AM, Marini C, Guerrini R, Noebels JL. Novel brain expression of ClC-1 chloride channels and enrichment of CLCN1 variants in epilepsy. Neurology. 2013 Mar 19; 80(12):1078-85. PMID: 23408874; PMCID: PMC3662306.
    33. Holth JK, Bomben VC, Reed JG, Inoue T, Younkin L, Younkin SG, Pautler RG, Botas J, Noebels JL. Tau loss attenuates neuronal network hyperexcitability in mouse and Drosophila genetic models of epilepsy. J Neurosci. 2013 Jan 23; 33(4):1651-9. PMID: 23345237; PMCID: PMC3711605.
    34. Eom T, Zhang C, Wang H, Lay K, Fak J, Noebels JL, Darnell RB. NOVA-dependent regulation of cryptic NMD exons controls synaptic protein levels after seizure. Elife. 2013; 2:e00178. PMID: 23359859; PMCID: PMC3552424.
    35. Lerche H, Shah M, Beck H, Noebels J, Johnston D, Vincent A. Ion channels in genetic and acquired forms of epilepsy. J Physiol. 2013 Feb 15; 591(4):753-64. PMID: 23090947; PMCID: PMC3591694.
    36. Ince-Dunn G, Okano HJ, Jensen KB, Park WY, Zhong R, Ule J, Mele A, Fak JJ, Yang C, Zhang C, Yoo J, Herre M, Okano H, Noebels JL, Darnell RB. Neuronal Elav-like (Hu) proteins regulate RNA splicing and abundance to control glutamate levels and neuronal excitability. Neuron. 2012 Sep 20; 75(6):1067-80. PMID: 22998874; PMCID: PMC3517991.
    37. Klassen TL, von Rüden EL, Drabek J, Noebels JL, Goldman AM. Comparative analytical utility of DNA derived from alternative human specimens for molecular autopsy and diagnostics. J Mol Diagn. 2012 Sep; 14(5):451-7. PMID: 22796560.
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    38. Glasscock E, Qian J, Kole MJ, Noebels JL. Transcompartmental reversal of single fibre hyperexcitability in juxtaparanodal Kv1.1-deficient vagus nerve axons by activation of nodal KCNQ channels. J Physiol. 2012 Aug 15; 590(16):3913-26. PMID: 22641786; PMCID: PMC3476640.
    39. de Curtis M, Nehlig A, Noebels J, Sankar R, Vezzani A. WONOEP XI: Workshop summary by the Scientific Organizing Committee. Epilepsia. 2012 Jul; 53(7):1275-6. PMID: 22578186.
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    40. Olivetti PR, Noebels JL. Interneuron, interrupted: molecular pathogenesis of ARX mutations and X-linked infantile spasms. Curr Opin Neurobiol. 2012 Oct; 22(5):859-65. PMID: 22565167; PMCID: PMC3437236.
    41. York B, Reineke EL, Sagen JV, Nikolai BC, Zhou S, Louet JF, Chopra AR, Chen X, Reed G, Noebels J, Adesina AM, Yu H, Wong LJ, Tsimelzon A, Hilsenbeck S, Stevens RD, Wenner BR, Ilkayeva O, Xu J, Newgard CB, O'Malley BW. Ablation of steroid receptor coactivator-3 resembles the human CACT metabolic myopathy. Cell Metab. 2012 May 2; 15(5):752-63. PMID: 22560224; PMCID: PMC3349072.
    42. Galanopoulou AS, Buckmaster PS, Staley KJ, Moshé SL, Perucca E, Engel J, Löscher W, Noebels JL, Pitkänen A, Stables J, White HS, O'Brien TJ, Simonato M. Identification of new epilepsy treatments: issues in preclinical methodology. Epilepsia. 2012 Mar; 53(3):571-82. PMID: 22292566; PMCID: PMC3551973.
    43. Zhu PJ, Huang W, Kalikulov D, Yoo JW, Placzek AN, Stoica L, Zhou H, Bell JC, Friedlander MJ, Krnjevi? K, Noebels JL, Costa-Mattioli M. Suppression of PKR promotes network excitability and enhanced cognition by interferon-?-mediated disinhibition. Cell. 2011 Dec 9; 147(6):1384-96. PMID: 22153080; PMCID: PMC3569515.
    44. McGuire AL, Oliver JM, Slashinski MJ, Graves JL, Wang T, Kelly PA, Fisher W, Lau CC, Goss J, Okcu M, Treadwell-Deering D, Goldman AM, Noebels JL, Hilsenbeck SG. To share or not to share: a randomized trial of consent for data sharing in genome research. Genet Med. 2011 Nov; 13(11):948-55. PMID: 21785360; PMCID: PMC3203320.
    45. Ward CS, Arvide EM, Huang TW, Yoo J, Noebels JL, Neul JL. MeCP2 is critical within HoxB1-derived tissues of mice for normal lifespan. J Neurosci. 2011 Jul 13; 31(28):10359-70. PMID: 21753013; PMCID: PMC3175623.
    46. Klassen T, Davis C, Goldman A, Burgess D, Chen T, Wheeler D, McPherson J, Bourquin T, Lewis L, Villasana D, Morgan M, Muzny D, Gibbs R, Noebels J. Exome sequencing of ion channel genes reveals complex profiles confounding personal risk assessment in epilepsy. Cell. 2011 Jun 24; 145(7):1036-48. PMID: 21703448; PMCID: PMC3131217.
    47. Shim DJ, Yang L, Reed JG, Noebels JL, Chiao PJ, Zheng H. Disruption of the NF-?B/I?B? Autoinhibitory Loop Improves Cognitive Performance and Promotes Hyperexcitability of Hippocampal Neurons. Mol Neurodegener. 2011; 6:42. PMID: 21663635; PMCID: PMC3141554.
    48. Hirsch LJ, Donner EJ, So EL, Jacobs M, Nashef L, Noebels JL, Buchhalter JR. Abbreviated report of the NIH/NINDS workshop on sudden unexpected death in epilepsy. Neurology. 2011 May 31; 76(22):1932-8. PMID: 21543734; PMCID: PMC3115809.
    49. Mark MD, Maejima T, Kuckelsberg D, Yoo JW, Hyde RA, Shah V, Gutierrez D, Moreno RL, Kruse W, Noebels JL, Herlitze S. Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations. J Neurosci. 2011 Mar 16; 31(11):4311-26. PMID: 21411672; PMCID: PMC3065835.
    50. Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, Yan F, Wu T, Hamto P, Devidze N, Yu GQ, Palop JJ, Noebels JL, Mucke L. Amyloid-?/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. J Neurosci. 2011 Jan 12; 31(2):700-11. PMID: 21228179; PMCID: PMC3325794.
    51. Qian J, Xu K, Yoo J, Chen TT, Andrews G, Noebels JL. Knockout of Zn transporters Zip-1 and Zip-3 attenuates seizure-induced CA1 neurodegeneration. J Neurosci. 2011 Jan 5; 31(1):97-104. PMID: 21209194; PMCID: PMC3078714.
    52. Noebels J. A perfect storm: Converging paths of epilepsy and Alzheimer's dementia intersect in the hippocampal formation. Epilepsia. 2011 Jan; 52 Suppl 1:39-46. PMID: 21214538; PMCID: PMC3058398.
    53. Noebels JL, Avoli M, Rogawski M, Olsen R, Delgado-Escueta AV. "Jasper's Basic Mechanisms of the Epilepsies" Workshop. Epilepsia. 2010 Dec; 51 Suppl 5:1-5. PMID: 21208201; PMCID: PMC4651849.
    54. Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY. Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes. Nature. 2010 Nov 11; 468(7321):263-9. PMID: 21068835; PMCID: PMC3057962.
    55. Peebles CL, Yoo J, Thwin MT, Palop JJ, Noebels JL, Finkbeiner S. Arc regulates spine morphology and maintains network stability in vivo. Proc Natl Acad Sci U S A. 2010 Oct 19; 107(42):18173-8. PMID: 20921410; PMCID: PMC2964216.
    56. Jiang YH, Pan Y, Zhu L, Landa L, Yoo J, Spencer C, Lorenzo I, Brilliant M, Noebels J, Beaudet AL. Altered ultrasonic vocalization and impaired learning and memory in Angelman syndrome mouse model with a large maternal deletion from Ube3a to Gabrb3. PLoS One. 2010; 5(8):e12278. PMID: 20808828; PMCID: PMC2924885.
    57. Zhang X, Bertaso F, Yoo JW, Baumgärtel K, Clancy SM, Lee V, Cienfuegos C, Wilmot C, Avis J, Hunyh T, Daguia C, Schmedt C, Noebels J, Jegla T. Deletion of the potassium channel Kv12.2 causes hippocampal hyperexcitability and epilepsy. Nat Neurosci. 2010 Sep; 13(9):1056-8. PMID: 20676103; PMCID: PMC2928878.
    58. Glasscock E, Yoo JW, Chen TT, Klassen TL, Noebels JL. Kv1.1 potassium channel deficiency reveals brain-driven cardiac dysfunction as a candidate mechanism for sudden unexplained death in epilepsy. J Neurosci. 2010 Apr 14; 30(15):5167-75. PMID: 20392939; PMCID: PMC2874941.
    59. Ottman R, Hirose S, Jain S, Lerche H, Lopes-Cendes I, Noebels JL, Serratosa J, Zara F, Scheffer IE. Genetic testing in the epilepsies--report of the ILAE Genetics Commission. Epilepsia. 2010 Apr; 51(4):655-70. PMID: 20100225; PMCID: PMC2855784.
    60. Price MG, Yoo JW, Burgess DL, Deng F, Hrachovy RA, Frost JD, Noebels JL. A triplet repeat expansion genetic mouse model of infantile spasms syndrome, Arx(GCG)10+7, with interneuronopathy, spasms in infancy, persistent seizures, and adult cognitive and behavioral impairment. J Neurosci. 2009 Jul 8; 29(27):8752-63. PMID: 19587282; PMCID: PMC2782569.
    61. Ernst WL, Noebels JL. Expanded alternative splice isoform profiling of the mouse Cav3.1/alpha1G T-type calcium channel. BMC Mol Biol. 2009; 10:53. PMID: 19480703; PMCID: PMC2696442.
    62. Jacobs MP, Leblanc GG, Brooks-Kayal A, Jensen FE, Lowenstein DH, Noebels JL, Spencer DD, Swann JW. Curing epilepsy: progress and future directions. Epilepsy Behav. 2009 Mar; 14(3):438-45. PMID: 19341977; PMCID: PMC2822433.
    63. Ernst WL, Zhang Y, Yoo JW, Ernst SJ, Noebels JL. Genetic enhancement of thalamocortical network activity by elevating alpha 1g-mediated low-voltage-activated calcium current induces pure absence epilepsy. J Neurosci. 2009 Feb 11; 29(6):1615-25. PMID: 19211869; PMCID: PMC2660673.
    64. Ernst SJ, Aguilar-Bryan L, Noebels JL. Sodium channel beta1 regulatory subunit deficiency reduces pancreatic islet glucose-stimulated insulin and glucagon secretion. Endocrinology. 2009 Mar; 150(3):1132-9. PMID: 18988673; PMCID: PMC2654754.
    65. Shuba YM, Perez-Reyes E, Lory P, Noebels J. T-type calcium channels: from discovery to channelopathies, 25 years of research. Channels (Austin). 2008 Jul-Aug; 2(4):299-302. PMID: 18769138.
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    66. Singh NA, Otto JF, Dahle EJ, Pappas C, Leslie JD, Vilaythong A, Noebels JL, White HS, Wilcox KS, Leppert MF. Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization. J Physiol. 2008 Jul 15; 586(14):3405-23. PMID: 18483067; PMCID: PMC2538806.
    67. Seal RP, Akil O, Yi E, Weber CM, Grant L, Yoo J, Clause A, Kandler K, Noebels JL, Glowatzki E, Lustig LR, Edwards RH. Sensorineural deafness and seizures in mice lacking vesicular glutamate transporter 3. Neuron. 2008 Jan 24; 57(2):263-75. PMID: 18215623; PMCID: PMC2293283.
    68. Noebels JL. 2006 Merritt Putnam Symposium: mapping epileptic circuitry. Epilepsia. 2008; 49 Suppl 3:1-2. PMID: 18304250.
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    69. Glasscock E, Qian J, Yoo JW, Noebels JL. Masking epilepsy by combining two epilepsy genes. Nat Neurosci. 2007 Dec; 10(12):1554-8. PMID: 17982453.
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    70. Noebels JL, Sidman RL. Persistent hypersynchronization of neocortical neurons in the mocha mutant of mouse. J Neurogenet. 2007 Oct-Dec; 21(4):253-6. PMID: 18161587.
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    71. Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 2007 Sep 6; 55(5):697-711. PMID: 17785178.
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    72. Lopez-Santiago LF, Meadows LS, Ernst SJ, Chen C, Malhotra JD, McEwen DP, Speelman A, Noebels JL, Maier SK, Lopatin AN, Isom LL. Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals. J Mol Cell Cardiol. 2007 Nov; 43(5):636-47. PMID: 17884088; PMCID: PMC2099572.
    73. Sisodiya S, Cross JH, Blümcke I, Chadwick D, Craig J, Crino PB, Debenham P, Delanty N, Elmslie F, Gardiner M, Golden J, Goldstein D, Greenberg DA, Guerrini R, Hanna M, Harris J, Harrison P, Johnson MR, Kirov G, Kullman DM, Makoff A, Marini C, Nabbout R, Nashef L, Noebels JL, Ottman R, Pirmohamed M, Pitkänen A, Scheffer I, Shorvon S, Sills G, Wood N, Zuberi S. Genetics of epilepsy: epilepsy research foundation workshop report. Epileptic Disord. 2007 Jun; 9(2):194-236. PMID: 17525034.
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    74. Bi W, Yan J, Shi X, Yuva-Paylor LA, Antalffy BA, Goldman A, Yoo JW, Noebels JL, Armstrong DL, Paylor R, Lupski JR. Rai1 deficiency in mice causes learning impairment and motor dysfunction, whereas Rai1 heterozygous mice display minimal behavioral phenotypes. Hum Mol Genet. 2007 Aug 1; 16(15):1802-13. PMID: 17517686.
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    75. Noebels JL. The Judith Hoyer Lecture: genes, pixels, patterns, and prevention. Epilepsy Behav. 2006 Nov; 9(3):379-85. PMID: 17029973; PMCID: PMC1866169.
    76. Goldman A, Noebels J. Invited comments on the Shostak and Ottman review. Epilepsia. 2006 Oct; 47(10):1750-1; author reply 1755-6. PMID: 17054704.
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    77. Qian J, Noebels JL. Exocytosis of vesicular zinc reveals persistent depression of neurotransmitter release during metabotropic glutamate receptor long-term depression at the hippocampal CA3-CA1 synapse. J Neurosci. 2006 May 31; 26(22):6089-95. PMID: 16738253.
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    78. Wang D, Pascual JM, Yang H, Engelstad K, Mao X, Cheng J, Yoo J, Noebels JL, De Vivo DC. A mouse model for Glut-1 haploinsufficiency. Hum Mol Genet. 2006 Apr 1; 15(7):1169-79. PMID: 16497725.
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    79. Goldman AM, Potocki L, Walz K, Lynch JK, Glaze DG, Lupski JR, Noebels JL. Epilepsy and chromosomal rearrangements in Smith-Magenis Syndrome [del(17)(p11.2p11.2)]. J Child Neurol. 2006 Feb; 21(2):93-8. PMID: 16566870.
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    80. Brenner R, Chen QH, Vilaythong A, Toney GM, Noebels JL, Aldrich RW. BK channel beta4 subunit reduces dentate gyrus excitability and protects against temporal lobe seizures. Nat Neurosci. 2005 Dec; 8(12):1752-9. PMID: 16261134.
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    81. Cobos I, Calcagnotto ME, Vilaythong AJ, Thwin MT, Noebels JL, Baraban SC, Rubenstein JL. Mice lacking Dlx1 show subtype-specific loss of interneurons, reduced inhibition and epilepsy. Nat Neurosci. 2005 Aug; 8(8):1059-68. PMID: 16007083.
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    82. Qian J, Noebels JL. Visualization of transmitter release with zinc fluorescence detection at the mouse hippocampal mossy fibre synapse. J Physiol. 2005 Aug 1; 566(Pt 3):747-58. PMID: 15919713; PMCID: PMC1464795.
    83. Noebels JL. Calcium channel "gaiting" and absence epilepsy. Epilepsy Curr. 2005 May-Jun; 5(3):95-7. PMID: 16145613; PMCID: PMC1198627.
    84. Senechal KR, Thaller C, Noebels JL. ADPEAF mutations reduce levels of secreted LGI1, a putative tumor suppressor protein linked to epilepsy. Hum Mol Genet. 2005 Jun 15; 14(12):1613-20. PMID: 15857855.
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    85. Jankovic J, Noebels JL. Genetic mouse models of essential tremor: are they essential? J Clin Invest. 2005 Mar; 115(3):584-6. PMID: 15765140; PMCID: PMC1052020.
    86. Mori M, Burgess DL, Gefrides LA, Foreman PJ, Opferman JT, Korsmeyer SJ, Cavalheiro EA, Naffah-Mazzacoratti MG, Noebels JL. Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons. Cell Death Differ. 2004 Nov; 11(11):1223-33. PMID: 15286683.
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    87. May P, Rohlmann A, Bock HH, Zurhove K, Marth JD, Schomburg ED, Noebels JL, Beffert U, Sweatt JD, Weeber EJ, Herz J. Neuronal LRP1 functionally associates with postsynaptic proteins and is required for normal motor function in mice. Mol Cell Biol. 2004 Oct; 24(20):8872-83. PMID: 15456862; PMCID: PMC517900.
    88. Collins AL, Levenson JM, Vilaythong AP, Richman R, Armstrong DL, Noebels JL, David Sweatt J, Zoghbi HY. Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. Hum Mol Genet. 2004 Nov 1; 13(21):2679-89. PMID: 15351775.
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    89. Zhang Y, Vilaythong AP, Yoshor D, Noebels JL. Elevated thalamic low-voltage-activated currents precede the onset of absence epilepsy in the SNAP25-deficient mouse mutant coloboma. J Neurosci. 2004 Jun 2; 24(22):5239-48. PMID: 15175394.
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    90. Chen C, Westenbroek RE, Xu X, Edwards CA, Sorenson DR, Chen Y, McEwen DP, O'Malley HA, Bharucha V, Meadows LS, Knudsen GA, Vilaythong A, Noebels JL, Saunders TL, Scheuer T, Shrager P, Catterall WA, Isom LL. Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture. J Neurosci. 2004 Apr 21; 24(16):4030-42. PMID: 15102918.
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    91. Houseweart MK, Vilaythong A, Yin XM, Turk B, Noebels JL, Myers RM. Apoptosis caused by cathepsins does not require Bid signaling in an in vivo model of progressive myoclonus epilepsy (EPM1). Cell Death Differ. 2003 Dec; 10(12):1329-35. PMID: 12934064.
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    92. Houseweart MK, Pennacchio LA, Vilaythong A, Peters C, Noebels JL, Myers RM. Cathepsin B but not cathepsins L or S contributes to the pathogenesis of Unverricht-Lundborg progressive myoclonus epilepsy (EPM1). J Neurobiol. 2003 Sep 15; 56(4):315-27. PMID: 12918016.
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    93. Qian J, Noebels JL. Topiramate alters excitatory synaptic transmission in mouse hippocampus. Epilepsy Res. 2003 Aug; 55(3):225-33. PMID: 12972176.
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    94. Noebels JL. Stiff Goats, Chloride Ions, and Idiopathic Generalized Epilepsy (IGE). Epilepsy Curr. 2003 Jul; 3(4):146-147. PMID: 15309062.
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    95. Walz K, Caratini-Rivera S, Bi W, Fonseca P, Mansouri DL, Lynch J, Vogel H, Noebels JL, Bradley A, Lupski JR. Modeling del(17)(p11.2p11.2) and dup(17)(p11.2p11.2) contiguous gene syndromes by chromosome engineering in mice: phenotypic consequences of gene dosage imbalance. Mol Cell Biol. 2003 May; 23(10):3646-55. PMID: 12724422; PMCID: PMC154242.
    96. Kantheti P, Diaz ME, Peden AE, Seong EE, Dolan DF, Robinson MS, Noebels JL, Burmeister ML. Genetic and phenotypic analysis of the mouse mutant mh2J, an Ap3d allele caused by IAP element insertion. Mamm Genome. 2003 Mar; 14(3):157-67. PMID: 12647238.
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    97. Noebels JL. How a Sodium Channel Mutation Causes Epilepsy. Epilepsy Curr. 2003 Mar; 3(2):70-71. PMID: 15309091.
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    98. Powell EM, Campbell DB, Stanwood GD, Davis C, Noebels JL, Levitt P. Genetic disruption of cortical interneuron development causes region- and GABA cell type-specific deficits, epilepsy, and behavioral dysfunction. J Neurosci. 2003 Jan 15; 23(2):622-31. PMID: 12533622.
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    99. Noebels JL. The biology of epilepsy genes. Annu Rev Neurosci. 2003; 26:599-625. PMID: 14527270.
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    100. Noebels JL. Exploring new gene discoveries in idiopathic generalized epilepsy. Epilepsia. 2003; 44 Suppl 2:16-21. PMID: 12752457.
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    101. Stables JP, Bertram EH, White HS, Coulter DA, Dichter MA, Jacobs MP, Loscher W, Lowenstein DH, Moshe SL, Noebels JL, Davis M. Models for epilepsy and epileptogenesis: report from the NIH workshop, Bethesda, Maryland. Epilepsia. 2002 Nov; 43(11):1410-20. PMID: 12423393.
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    102. Anderson E, Berkovic S, Dulac O, Gardiner M, Jain S, Laue Friis M, Lindhout D, Noebels J, Ottman R, Scaramelli A, Serratosa J, Steinlein O, Avanzini G, Bailey-Wilson J, Cardon L, Fischbach R, Gwinn-Hardy K, Leppert M, Ott J, Lindblad-Toh K, Weiss K, Laue-Friis M. ILAE genetics commission conference report: molecular analysis of complex genetic epilepsies. Epilepsia. 2002 Oct; 43(10):1262-7. PMID: 12366744.
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    103. Zhang Y, Mori M, Burgess DL, Noebels JL. Mutations in high-voltage-activated calcium channel genes stimulate low-voltage-activated currents in mouse thalamic relay neurons. J Neurosci. 2002 Aug 1; 22(15):6362-71. PMID: 12151514.
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    104. Shahbazian M, Young J, Yuva-Paylor L, Spencer C, Antalffy B, Noebels J, Armstrong D, Paylor R, Zoghbi H. Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron. 2002 Jul 18; 35(2):243-54. PMID: 12160743.
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    105. Noebels JL. A Gene for JME at Last: The alpha1 GABA Receptor Subunit. Epilepsy Curr. 2002 Jul; 2(4):131-132. PMID: 15309143.
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    106. Poolos NP, Das S, Clark GD, Lardizabal D, Noebels JL, Wyllie E, Dobyns WB. Males with epilepsy, complete subcortical band heterotopia, and somatic mosaicism for DCX. Neurology. 2002 May 28; 58(10):1559-62. PMID: 12034802.
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    107. Noebels JL. Human Epilepsy Can Be Linked to a Defective Calcium Channel. Epilepsy Curr. 2002 May; 2(3):95. PMID: 15309155.
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    108. Noebels JL. Sodium channel gene expression and epilepsy. Novartis Found Symp. 2002; 241:109-20; discussion 120-3, 226-32. PMID: 11771641.
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    109. Jacobs MP, Fischbach GD, Davis MR, Dichter MA, Dingledine R, Lowenstein DH, Morrell MJ, Noebels JL, Rogawski MA, Spencer SS, Theodore WH. Future directions for epilepsy research. Neurology. 2001 Nov 13; 57(9):1536-42. PMID: 11706087.
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    110. Heilstedt HA, Burgess DL, Anderson AE, Chedrawi A, Tharp B, Lee O, Kashork CD, Starkey DE, Wu YQ, Noebels JL, Shaffer LG, Shapira SK. Loss of the potassium channel beta-subunit gene, KCNAB2, is associated with epilepsy in patients with 1p36 deletion syndrome. Epilepsia. 2001 Sep; 42(9):1103-11. PMID: 11580756.
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    111. Qian J, Noebels JL. Presynaptic Ca2+ channels and neurotransmitter release at the terminal of a mouse cortical neuron. J Neurosci. 2001 Jun 1; 21(11):3721-8. PMID: 11356859.
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    112. Qiao X, Suri C, Knusel B, Noebels JL. Absence of hippocampal mossy fiber sprouting in transgenic mice overexpressing brain-derived neurotrophic factor. J Neurosci Res. 2001 May 1; 64(3):268-76. PMID: 11319771.
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    113. Zwingman TA, Neumann PE, Noebels JL, Herrup K. Rocker is a new variant of the voltage-dependent calcium channel gene Cacna1a. J Neurosci. 2001 Feb 15; 21(4):1169-78. PMID: 11160387.
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    114. Burgess DL, Gefrides LA, Foreman PJ, Noebels JL. A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. Genomics. 2001 Feb 1; 71(3):339-50. PMID: 11170751.
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    115. Noebels JL. Modeling human epilepsies in mice. Epilepsia. 2001; 42 Suppl 5:11-5. PMID: 11887961.
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    116. Lau D, Vega-Saenz de Miera EC, Contreras D, Ozaita A, Harvey M, Chow A, Noebels JL, Paylor R, Morgan JI, Leonard CS, Rudy B. Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking Kv3.2 K+ channel proteins. J Neurosci. 2000 Dec 15; 20(24):9071-85. PMID: 11124984.
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    117. Matsuura T, Yamagata T, Burgess DL, Rasmussen A, Grewal RP, Watase K, Khajavi M, McCall AE, Davis CF, Zu L, Achari M, Pulst SM, Alonso E, Noebels JL, Nelson DL, Zoghbi HY, Ashizawa T. Large expansion of the ATTCT pentanucleotide repeat in spinocerebellar ataxia type 10. Nat Genet. 2000 Oct; 26(2):191-4. PMID: 11017075.
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    118. Burgess DL, Noebels JL. Calcium channel defects in models of inherited generalized epilepsy. Epilepsia. 2000 Aug; 41(8):1074-5. PMID: 10961647.
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    119. Kellaway P, Mizrahi EM, Noebels JL. Benign focal epilepsies of childhood: genetically determined pathophysiology. Report of an international workshop. Epilepsia. 2000 Aug; 41(8):1049-50. PMID: 10961636.
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    120. Steinlein OK, Noebels JL. Ion channels and epilepsy in man and mouse. Curr Opin Genet Dev. 2000 Jun; 10(3):286-91. PMID: 10826987.
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    121. Liu M, Pleasure SJ, Collins AE, Noebels JL, Naya FJ, Tsai MJ, Lowenstein DH. Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):865-70. PMID: 10639171; PMCID: PMC15422.
    122. Ayata C, Shimizu-Sasamata M, Lo EH, Noebels JL, Moskowitz MA. Impaired neurotransmitter release and elevated threshold for cortical spreading depression in mice with mutations in the alpha1A subunit of P/Q type calcium channels. Neuroscience. 2000; 95(3):639-45. PMID: 10670432.
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    123. Burgess DL, Matsuura T, Ashizawa T, Noebels JL. Genetic localization of the Ca2+ channel gene CACNG2 near SCA10 on chromosome 22q13. Epilepsia. 2000 Jan; 41(1):24-7. PMID: 10643919.
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    124. Qian J, Noebels JL. Presynaptic Ca(2+) influx at a mouse central synapse with Ca(2+) channel subunit mutations. J Neurosci. 2000 Jan 1; 20(1):163-70. PMID: 10627593.
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    125. Burgess DL, Davis CF, Gefrides LA, Noebels JL. Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication. Genome Res. 1999 Dec; 9(12):1204-13. PMID: 10613843; PMCID: PMC311002.
    126. Burgess DL, Noebels JL. Single gene defects in mice: the role of voltage-dependent calcium channels in absence models. Epilepsy Res. 1999 Sep; 36(2-3):111-22. PMID: 10515159.
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    127. Hartmann HA, Colom LV, Sutherland ML, Noebels JL. Selective localization of cardiac SCN5A sodium channels in limbic regions of rat brain. Nat Neurosci. 1999 Jul; 2(7):593-5. PMID: 10404176.
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    128. Burgess DL, Noebels JL. Voltage-dependent calcium channel mutations in neurological disease. Ann N Y Acad Sci. 1999 Apr 30; 868:199-212. PMID: 10414295.
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    129. Burgess DL, Biddlecome GH, McDonough SI, Diaz ME, Zilinski CA, Bean BP, Campbell KP, Noebels JL. beta subunit reshuffling modifies N- and P/Q-type Ca2+ channel subunit compositions in lethargic mouse brain. Mol Cell Neurosci. 1999 Apr; 13(4):293-311. PMID: 10328888.
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    130. Sutherland ML, Williams SH, Abedi R, Overbeek PA, Pfaffinger PJ, Noebels JL. Overexpression of a Shaker-type potassium channel in mammalian central nervous system dysregulates native potassium channel gene expression. Proc Natl Acad Sci U S A. 1999 Mar 2; 96(5):2451-5. PMID: 10051663; PMCID: PMC26805.
    131. Clark GD, Noebels JL. Cortin disaster: lissencephaly genes spell double trouble for the developing brain. Ann Neurol. 1999 Feb; 45(2):141-2. PMID: 9989613.
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    132. Noebels JL. Single-gene models of epilepsy. Adv Neurol. 1999; 79:227-38. PMID: 10514817.
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    133. Nahm WK, Noebels JL. Nonobligate role of early or sustained expression of immediate-early gene proteins c-fos, c-jun, and Zif/268 in hippocampal mossy fiber sprouting. J Neurosci. 1998 Nov 15; 18(22):9245-55. PMID: 9801364.
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    134. Pennacchio LA, Bouley DM, Higgins KM, Scott MP, Noebels JL, Myers RM. Progressive ataxia, myoclonic epilepsy and cerebellar apoptosis in cystatin B-deficient mice. Nat Genet. 1998 Nov; 20(3):251-8. PMID: 9806543.
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    135. Jiang YH, Armstrong D, Albrecht U, Atkins CM, Noebels JL, Eichele G, Sweatt JD, Beaudet AL. Mutation of the Angelman ubiquitin ligase in mice causes increased cytoplasmic p53 and deficits of contextual learning and long-term potentiation. Neuron. 1998 Oct; 21(4):799-811. PMID: 9808466.
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    136. Noebels JL. Ion Channelopathies and Heritable Epilepsy. News Physiol Sci. 1998 Oct; 13:255-256. PMID: 11390799.
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    137. Kantheti P, Qiao X, Diaz ME, Peden AA, Meyer GE, Carskadon SL, Kapfhamer D, Sufalko D, Robinson MS, Noebels JL, Burmeister M. Mutation in AP-3 delta in the mocha mouse links endosomal transport to storage deficiency in platelets, melanosomes, and synaptic vesicles. Neuron. 1998 Jul; 21(1):111-22. PMID: 9697856.
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    138. Westenbroek RE, Bausch SB, Lin RC, Franck JE, Noebels JL, Catterall WA. Upregulation of L-type Ca2+ channels in reactive astrocytes after brain injury, hypomyelination, and ischemia. J Neurosci. 1998 Apr 1; 18(7):2321-34. PMID: 9502793.
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    139. Kash SF, Johnson RS, Tecott LH, Noebels JL, Mayfield RD, Hanahan D, Baekkeskov S. Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase. Proc Natl Acad Sci U S A. 1997 Dec 9; 94(25):14060-5. PMID: 9391152; PMCID: PMC28432.
    140. Cox GA, Lutz CM, Yang CL, Biemesderfer D, Bronson RT, Fu A, Aronson PS, Noebels JL, Frankel WN. Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice. Cell. 1997 Oct 3; 91(1):139-48. PMID: 9335342.
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    141. Cattanach BM, Barr JA, Beechey CV, Martin J, Noebels J, Jones J. A candidate model for Angelman syndrome in the mouse. Mamm Genome. 1997 Jul; 8(7):472-8. PMID: 9195990.
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    142. Burgess DL, Jones JM, Meisler MH, Noebels JL. Mutation of the Ca2+ channel beta subunit gene Cchb4 is associated with ataxia and seizures in the lethargic (lh) mouse. Cell. 1997 Feb 7; 88(3):385-92. PMID: 9039265.
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    143. Di Pasquale E, Keegan KD, Noebels JL. Increased excitability and inward rectification in layer V cortical pyramidal neurons in the epileptic mutant mouse Stargazer. J Neurophysiol. 1997 Feb; 77(2):621-31. PMID: 9065835.
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    144. Noebels JL, Qiao X, Nahm WK. Neurogenetic approaches to axon sprouting in the hippocampus. Adv Neurol. 1997; 72:35-44. PMID: 8993682.
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    145. Sutherland ML, Delaney TA, Noebels JL. Glutamate transporter mRNA expression in proliferative zones of the developing and adult murine CNS. J Neurosci. 1996 Apr 1; 16(7):2191-207. PMID: 8601800.
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    146. Noebels JL. Targeting epilepsy genes. Neuron. 1996 Feb; 16(2):241-4. PMID: 8789939.
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    147. Qiao X, Hefti F, Knusel B, Noebels JL. Selective failure of brain-derived neurotrophic factor mRNA expression in the cerebellum of stargazer, a mutant mouse with ataxia. J Neurosci. 1996 Jan 15; 16(2):640-8. PMID: 8551348.
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    148. Noebels JL, Sutherland ML, Nahm WK, DiPasquale E. Molecular and cellular plasticity in developing epileptic brain. Cold Spring Harb Symp Quant Biol. 1996; 61:319-26. PMID: 9246461.
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    149. Wang H, Allen ML, Grigg JJ, Noebels JL, Tempel BL. Hypomyelination alters K+ channel expression in mouse mutants shiverer and Trembler. Neuron. 1995 Dec; 15(6):1337-47. PMID: 8845157.
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    150. Sutherland ML, Delaney TA, Noebels JL. Molecular characterization of a high-affinity mouse glutamate transporter. Gene. 1995 Sep 11; 162(2):271-4. PMID: 7557442.
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    151. Chafetz RS, Nahm WK, Noebels JL. Aberrant expression of neuropeptide Y in hippocampal mossy fibers in the absence of local cell injury following the onset of spike-wave synchronization. Brain Res Mol Brain Res. 1995 Jul; 31(1-2):111-21. PMID: 7476019.
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    152. Noebels JL. Single locus mutations in mice expressing generalized spike-wave absence epilepsies. Ital J Neurol Sci. 1995 Feb-Mar; 16(1-2):107-11. PMID: 7642343.
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    153. Frankel WN, Taylor BA, Noebels JL, Lutz CM. Genetic epilepsy model derived from common inbred mouse strains. Genetics. 1994 Oct; 138(2):481-9. PMID: 7828829; PMCID: PMC1206164.
    154. Helekar SA, Noebels JL. Analysis of voltage-gated and synaptic conductances contributing to network excitability defects in the mutant mouse tottering. J Neurophysiol. 1994 Jan; 71(1):1-10. PMID: 8158221.
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    155. Wu SM, Qiao X, Noebels JL, Yang XL. Localization and modulatory actions of zinc in vertebrate retina. Vision Res. 1993 Dec; 33(18):2611-6. PMID: 8296456.
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    156. Qiao X, Noebels JL. Developmental analysis of hippocampal mossy fiber outgrowth in a mutant mouse with inherited spike-wave seizures. J Neurosci. 1993 Nov; 13(11):4622-35. PMID: 8229188.
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    157. Buckwalter MS, Testa CM, Noebels JL, Camper SA. Genetic mapping and evaluation of candidate genes for spasmodic, a neurological mouse mutation with abnormal startle response. Genomics. 1993 Aug; 17(2):279-86. PMID: 8406478.
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    158. Westenbroek RE, Noebels JL, Catterall WA. Elevated expression of type II Na+ channels in hypomyelinated axons of shiverer mouse brain. J Neurosci. 1992 Jun; 12(6):2259-67. PMID: 1318958.
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    159. Helekar SA, Noebels JL. A burst-dependent hippocampal excitability defect elicited by potassium at the developmental onset of spike-wave seizures in the Tottering mutant. Brain Res Dev Brain Res. 1992 Feb 21; 65(2):205-10. PMID: 1572065.
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    160. Noebels JL, Marcom PK, Jalilian-Tehrani MH. Sodium channel density in hypomyelinated brain increased by myelin basic protein gene deletion. Nature. 1991 Aug 1; 352(6334):431-4. PMID: 1713650.
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    161. Qiao XX, Noebels JL. Genetic and phenotypic heterogeneity of inherited spike-wave epilepsy: two mutant gene loci with independent cerebral excitability defects. Brain Res. 1991 Jul 26; 555(1):43-50. PMID: 1933329.
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    162. Helekar SA, Noebels JL. Synchronous hippocampal bursting reveals network excitability defects in an epilepsy gene mutation. Proc Natl Acad Sci U S A. 1991 Jun 1; 88(11):4736-40. PMID: 2052555; PMCID: PMC51741.
    163. Noebels JL. Mutational analysis of spike-wave epilepsy phenotypes. Epilepsy Res Suppl. 1991; 4:201-12. PMID: 1815603.
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    164. Noebels JL, Qiao X, Bronson RT, Spencer C, Davisson MT. Stargazer: a new neurological mutant on chromosome 15 in the mouse with prolonged cortical seizures. Epilepsy Res. 1990 Nov; 7(2):129-35. PMID: 2289471.
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    165. Noebels JL, Rutecki PA. Altered hippocampal network excitability in the hypernoradrenergic mutant mouse tottering. Brain Res. 1990 Aug 6; 524(2):225-30. PMID: 2292005.
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    166. Noebels JL, Sidman RL. Persistent hypersynchronization of neocortical neurons in the mocha mutant of mouse. J Neurogenet. 1989 Sep; 6(1):53-6. PMID: 2778559.
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    167. Noebels JL. Mutational analysis of inherited epilepsies. Adv Neurol. 1986; 44:97-113. PMID: 2871726.
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    168. Noebels JL. A single gene error of noradrenergic axon growth synchronizes central neurones. Nature. 1984 Aug 2-8; 310(5976):409-11. PMID: 6462226.
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    169. Noebels JL. Isolating single genes of the inherited epilepsies. Ann Neurol. 1984; 16 Suppl:S18-21. PMID: 6095738.
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    170. Levitt P, Noebels JL. Mutant mouse tottering: selective increase of locus ceruleus axons in a defined single-locus mutation. Proc Natl Acad Sci U S A. 1981 Jul; 78(7):4630-4. PMID: 6945603; PMCID: PMC319847.
    171. Noebels JL. Analysis of inherited epilepsy using single locus mutations in mice. Fed Proc. 1979 Sep; 38(10):2405-10. PMID: 383515.
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    172. Noebels JL, Sidman RL. Inherited epilepsy: spike-wave and focal motor seizures in the mutant mouse tottering. Science. 1979 Jun 22; 204(4399):1334-6. PMID: 572084.
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    173. Noebels JL, Prince DA. Excitability changes in thalamocortical relay neurons during synchronous discharges in cat neocortex. J Neurophysiol. 1978 Sep; 41(5):1282-96. PMID: 212538.
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    174. Noebels JL, Prince DA. Development of focal seizures in cerebral cortex: role of axon terminal bursting. J Neurophysiol. 1978 Sep; 41(5):1267-81. PMID: 702194.
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    175. Noebels JL, Roth WT, Kopell BS. Cortical slow potentials and the occipital EEG in congenital blindness. J Neurol Sci. 1978 Jun; 37(1-2):51-8. PMID: 690664.
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    176. Noebels JL, Prince DA. Presynaptic origin of penicillin after discharges at mammalian nerve terminals. Brain Res. 1977 Dec 9; 138(1):59-74. PMID: 201346.
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    177. Noebels JL, Pedley TA. Anatomic localization of topically applied [14C]penicillin during experimental focal epilepsy in cat neocortex. Brain Res. 1977 Apr 15; 125(2):293-303. PMID: 404001.
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    178. Schwartzkroin PA, Futamachi KJ, Noebels JL, Prince DA. Transcallosal effects of a cortical epileptiform focus. Brain Res. 1975 Nov 28; 99(1):59-68. PMID: 1188986.
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