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AUSTIN J COONEY

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
DivisionSurgery-Plastic Surgery Div
AddressOne Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleAdjunct Associate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Lan ZJ, Krause MS, Redding SD, Li X, Wu GZ, Zhou HX, Bohler HC, Ko C, Cooney AJ, Zhou J, Lei ZM. Selective deletion of Pten in theca-interstitial cells leads to androgen excess and ovarian dysfunction in mice. Mol Cell Endocrinol. 2017 Jan 27. PMID: 28137614.
      View in: PubMed
    2. Chen IC, Hernandez C, Xu X, Cooney A, Wang Y, McCarrey JR. Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate. Stem Cells Dev. 2016 Oct 12. PMID: 27627671.
      View in: PubMed
    3. Liu Y, Chen L, Diaz AD, Benham A, Xu X, Wijaya CS, Fa'ak F, Luo W, Soibam B, Azares A, Yu W, Lyu Q, Stewart MD, Gunaratne P, Cooney A, McConnell BK, Schwartz RJ. Mesp1 Marked Cardiac Progenitor Cells Repair Infarcted Mouse Hearts. Sci Rep. 2016; 6:31457. PMID: 27538477.
      View in: PubMed
    4. Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, Liu Y. miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification. Proc Natl Acad Sci U S A. 2016 Aug 23; 113(34):9551-6. PMID: 27512039.
      View in: PubMed
    5. Lan ZJ, Hu Y, Zhang S, Li X, Zhou H, Ding J, Klinge CM, Radde BN, Cooney AJ, Zhang J, Lei Z. GGNBP2 acts as a tumor suppressor by inhibiting estrogen receptor ? activity in breast cancer cells. Breast Cancer Res Treat. 2016 Jul; 158(2):263-76. PMID: 27357812.
      View in: PubMed
    6. Wang H, Xi Y, Zheng Y, Wang X, Cooney AJ. Generation of electrophysiologically functional cardiomyocytes from mouse induced pluripotent stem cells. Stem Cell Res. 2016 Mar; 16(2):522-30. PMID: 26972055; PMCID: PMC4828332 [Available on 03/01/17].
    7. Wang H, Wang X, Xu X, Kyba M, Cooney AJ. Germ Cell Nuclear Factor (GCNF) Represses Oct4 Expression and Globally Modulates Gene Expression in Human Embryonic Stem (hES) Cells. J Biol Chem. 2016 Apr 15; 291(16):8644-52. PMID: 26769970; PMCID: PMC4861434.
    8. Li S, Moore AK, Zhu J, Li X, Zhou H, Lin J, He Y, Xing F, Pan Y, Bohler HC, Ding J, Cooney AJ, Lan Z, Lei Z. Ggnbp2 Is Essential for Pregnancy Success via Regulation of Mouse Trophoblast Stem Cell Proliferation and Differentiation. Biol Reprod. 2016 Feb; 94(2):41. PMID: 26764350; PMCID: PMC4787627 [Available on 02/01/17].
    9. Soibam B, Benham A, Kim J, Weng KC, Yang L, Xu X, Robertson M, Azares A, Cooney AJ, Schwartz RJ, Liu Y. Genome-Wide Identification of MESP1 Targets Demonstrates Primary Regulation Over Mesendoderm Gene Activity. Stem Cells. 2015 Nov; 33(11):3254-65. PMID: 26205879.
      View in: PubMed
    10. Hirsch CL, Akdemir ZC, Wang L, Jayakumaran G, Trcka D, Weiss A, Hernandez JJ, Pan Q, Han H, Xu X, Xia Z, Salinger AP, Wilson M, Vizeacoumar F, Datti A, Li W, Cooney AJ, Barton MC, Blencowe BJ, Wrana JL, Dent SY. Corrigendum: Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming. Genes Dev. 2015 Jun 15; 29(12):1341. PMID: 26109054.
      View in: PubMed
    11. Hirsch CL, Coban Akdemir Z, Wang L, Jayakumaran G, Trcka D, Weiss A, Hernandez JJ, Pan Q, Han H, Xu X, Xia Z, Salinger AP, Wilson M, Vizeacoumar F, Datti A, Li W, Cooney AJ, Barton MC, Blencowe BJ, Wrana JL, Dent SY. Myc and SAGA rewire an alternative splicing network during early somatic cell reprogramming. Genes Dev. 2015 Apr 15; 29(8):803-16. PMID: 25877919; PMCID: PMC4403257.
    12. Liu L, Liu L, Leung LH, Cooney AJ, Chen C, Rosengart TK, Ma Y, Yang J. Knockdown of SALL4 Protein Enhances All-trans Retinoic Acid-induced Cellular Differentiation in Acute Myeloid Leukemia Cells. J Biol Chem. 2015 Apr 24; 290(17):10599-609. PMID: 25737450; PMCID: PMC4409227.
    13. Liu S, Bou G, Sun R, Guo S, Xue B, Wei R, Cooney AJ, Liu Z. Sox2 is the faithful marker for pluripotency in pig: evidence from embryonic studies. Dev Dyn. 2015 Apr; 244(4):619-27. PMID: 25619399.
      View in: PubMed
    14. Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Araúzo-Bravo MJ, Gentile L, Greber B, Hübner K, Sebastiano V, Wu G, Schöler HR, Cooney AJ. Germ cell nuclear factor regulates gametogenesis in developing gonads. PLoS One. 2014; 9(8):e103985. PMID: 25140725; PMCID: PMC4139263.
    15. Wang H, Wang X, Archer TK, Zwaka TP, Cooney AJ. GCNF-dependent activation of cyclin D1 expression via repression of Mir302a during ESC differentiation. Stem Cells. 2014 Jun; 32(6):1527-37. PMID: 24578347; PMCID: PMC4091926.
    16. Mathison M, Singh VP, Gersch RP, Ramirez MO, Cooney A, Kaminsky SM, Chiuchiolo MJ, Nasser A, Yang J, Crystal RG, Rosengart TK. "Triplet" polycistronic vectors encoding Gata4, Mef2c, and Tbx5 enhances postinfarct ventricular functional improvement compared with singlet vectors. J Thorac Cardiovasc Surg. 2014 Oct; 148(4):1656-1664.e2. PMID: 24755332.
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    17. Chakravarti D, Su X, Cho MS, Bui NH, Coarfa C, Venkatanarayan A, Benham AL, Flores González RE, Alana J, Xiao W, Leung ML, Vin H, Chan IL, Aquino A, Müller N, Wang H, Cooney AJ, Parker-Thornburg J, Tsai KY, Gunaratne PH, Flores ER. Induced multipotency in adult keratinocytes through down-regulation of ?Np63 or DGCR8. Proc Natl Acad Sci U S A. 2014 Feb 4; 111(5):E572-81. PMID: 24449888; PMCID: PMC3918754.
    18. Wang H, Wang X, Xu X, Zwaka TP, Cooney AJ. Epigenetic reprogramming of the germ cell nuclear factor gene is required for proper differentiation of induced pluripotent cells. Stem Cells. 2013 Dec; 31(12):2659-66. PMID: 23495137; PMCID: PMC3731425.
    19. Seabrook JL, Cantlon JD, Cooney AJ, McWhorter EE, Fromme BA, Bouma GJ, Anthony RV, Winger QA. Role of LIN28A in mouse and human trophoblast cell differentiation. Biol Reprod. 2013 Oct; 89(4):95. PMID: 24006280; PMCID: PMC4076397.
    20. Akdemir KC, Jain AK, Allton K, Aronow B, Xu X, Cooney AJ, Li W, Barton MC. Genome-wide profiling reveals stimulus-specific functions of p53 during differentiation and DNA damage of human embryonic stem cells. Nucleic Acids Res. 2014 Jan; 42(1):205-23. PMID: 24078252; PMCID: PMC3874181.
    21. Tennakoon JB, Wang H, Coarfa C, Cooney AJ, Gunaratne PH. Chromatin changes in dicer-deficient mouse embryonic stem cells in response to retinoic acid induced differentiation. PLoS One. 2013; 8(9):e74556. PMID: 24040281; PMCID: PMC3767645.
    22. Wang Q, Cooney AJ. Revisiting the role of GCNF in embryonic development. Semin Cell Dev Biol. 2013 Dec; 24(10-12):679-86. PMID: 24029702.
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    23. Li Y, Yu W, Cooney AJ, Schwartz RJ, Liu Y. Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element. Stem Cells. 2013 Jun; 31(6):1213-7. PMID: 23417899.
      View in: PubMed
    24. Mahendram S, Kelly KF, Paez-Parent S, Mahmood S, Polena E, Cooney AJ, Doble BW. Ectopic ?-catenin expression partially mimics the effects of stabilized ?-catenin on embryonic stem cell differentiation. PLoS One. 2013; 8(5):e65320. PMID: 23724138; PMCID: PMC3664634.
    25. Wang Q, Wagner RT, Cooney AJ. Regulatable in vivo biotinylation expression system in mouse embryonic stem cells. PLoS One. 2013; 8(5):e63532. PMID: 23667633; PMCID: PMC3646753.
    26. Wagner RT, Cooney AJ. Minireview: the diverse roles of nuclear receptors in the regulation of embryonic stem cell pluripotency. Mol Endocrinol. 2013 Jun; 27(6):864-78. PMID: 23504955; PMCID: PMC3656235.
    27. Wang Q, Cooney AJ. The role of nuclear receptors in embryonic stem cells. Adv Exp Med Biol. 2013; 786:287-306. PMID: 23696363.
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    28. Ochsner SA, Watkins CM, McOwiti A, Xu X, Darlington YF, Dehart MD, Cooney AJ, Steffen DL, Becnel LB, McKenna NJ. Transcriptomine, a web resource for nuclear receptor signaling transcriptomes. Physiol Genomics. 2012 Sep 1; 44(17):853-63. PMID: 22786849; PMCID: PMC3472459.
    29. García-Becerra R, Ordaz-Rosado D, Noé G, Chávez B, Cooney AJ, Larrea F. Comparison of 7?-methyl-19-nortestosterone effectiveness alone or combined with progestins on androgen receptor mediated-transactivation. Reproduction. 2012 Feb; 143(2):211-9. PMID: 22065861.
      View in: PubMed
    30. Luo Z, Xu X, Gu P, Lonard D, Gunaratne PH, Cooney AJ, Azencott R. miRNA regulatory circuits in ES cells differentiation: a chemical kinetics modeling approach. PLoS One. 2011; 6(10):e23263. PMID: 22039400; PMCID: PMC3198445.
    31. Gu P, Xu X, Le Menuet D, Chung AC, Cooney AJ. Differential recruitment of methyl CpG-binding domain factors and DNA methyltransferases by the orphan receptor germ cell nuclear factor initiates the repression and silencing of Oct4. Stem Cells. 2011 Jul; 29(7):1041-51. PMID: 21608077; PMCID: PMC3468724.
    32. Deng JM, Satoh K, Wang H, Chang H, Zhang Z, Stewart MD, Cooney AJ, Behringer RR. Generation of viable male and female mice from two fathers. Biol Reprod. 2011 Mar; 84(3):613-8. PMID: 21148107; PMCID: PMC3043133.
    33. Wagner RT, Xu X, Yi F, Merrill BJ, Cooney AJ. Canonical Wnt/?-catenin regulation of liver receptor homolog-1 mediates pluripotency gene expression. Stem Cells. 2010 Oct; 28(10):1794-804. PMID: 20734354; PMCID: PMC2996860.
    34. Wagner RT, Lewis J, Cooney A, Chan L. Stem cell approaches for the treatment of type 1 diabetes mellitus. Transl Res. 2010 Sep; 156(3):169-79. PMID: 20801414; PMCID: PMC2935591.
    35. Rivera-Guevara C, Pérez-Alvarez V, García-Becerra R, Ordaz-Rosado D, Morales-Ríos MS, Hernández-Gallegos E, Cooney AJ, Bravo-Gómez ME, Larrea F, Camacho J. Genomic action of permanently charged tamoxifen derivatives via estrogen receptor-alpha. Bioorg Med Chem. 2010 Aug 1; 18(15):5593-601. PMID: 20621492.
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    36. García-Becerra R, Berno V, Ordaz-Rosado D, Sharp ZD, Cooney AJ, Mancini MA, Larrea F. Ligand-induced large-scale chromatin dynamics as a biosensor for the detection of estrogen receptor subtype selective ligands. Gene. 2010 Jun 15; 458(1-2):37-44. PMID: 20347019.
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    37. Uhlenhaut NH, Jakob S, Anlag K, Eisenberger T, Sekido R, Kress J, Treier AC, Klugmann C, Klasen C, Holter NI, Riethmacher D, Schütz G, Cooney AJ, Lovell-Badge R, Treier M. Somatic sex reprogramming of adult ovaries to testes by FOXL2 ablation. Cell. 2009 Dec 11; 139(6):1130-42. PMID: 20005806.
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    38. Adhikari D, Zheng W, Shen Y, Gorre N, Hämäläinen T, Cooney AJ, Huhtaniemi I, Lan ZJ, Liu K. Tsc/mTORC1 signaling in oocytes governs the quiescence and activation of primordial follicles. Hum Mol Genet. 2010 Feb 1; 19(3):397-410. PMID: 19843540; PMCID: PMC2798719.
    39. McKenna NJ, Cooney AJ, DeMayo FJ, Downes M, Glass CK, Lanz RB, Lazar MA, Mangelsdorf DJ, Moore DD, Qin J, Steffen DL, Tsai MJ, Tsai SY, Yu R, Margolis RN, Evans RM, O'Malley BW. Minireview: Evolution of NURSA, the Nuclear Receptor Signaling Atlas. Mol Endocrinol. 2009 Jun; 23(6):740-6. PMID: 19423650; PMCID: PMC2691684.
    40. Wagner RT, Cooney AJ. OCT4: less is more. Cell Res. 2009 May; 19(5):527-8. PMID: 19421239.
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    41. Akamatsu W, DeVeale B, Okano H, Cooney AJ, van der Kooy D. Suppression of Oct4 by germ cell nuclear factor restricts pluripotency and promotes neural stem cell development in the early neural lineage. J Neurosci. 2009 Feb 18; 29(7):2113-24. PMID: 19228964.
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    42. Lan ZJ, Xu X, Chung AC, Cooney AJ. Extra-germ cell expression of mouse nuclear receptor subfamily 6, group A, member 1 (NR6A1). Biol Reprod. 2009 May; 80(5):905-12. PMID: 19164181; PMCID: PMC2804840.
    43. Huang X, Andreu-Vieyra CV, Wang M, Cooney AJ, Matzuk MM, Zhang P. Preimplantation mouse embryos depend on inhibitory phosphorylation of separase to prevent chromosome missegregation. Mol Cell Biol. 2009 Mar; 29(6):1498-505. PMID: 19124608; PMCID: PMC2648233.
    44. Bridges PJ, Koo Y, Kang DW, Hudgins-Spivey S, Lan ZJ, Xu X, DeMayo F, Cooney A, Ko C. Generation of Cyp17iCre transgenic mice and their application to conditionally delete estrogen receptor alpha (Esr1) from the ovary and testis. Genesis. 2008 Sep; 46(9):499-505. PMID: 18781648; PMCID: PMC2637183.
    45. Gu P, Reid JG, Gao X, Shaw CA, Creighton C, Tran PL, Zhou X, Drabek RB, Steffen DL, Hoang DM, Weiss MK, Naghavi AO, El-daye J, Khan MF, Legge GB, Wheeler DA, Gibbs RA, Miller JN, Cooney AJ, Gunaratne PH. Novel microRNA candidates and miRNA-mRNA pairs in embryonic stem (ES) cells. PLoS One. 2008; 3(7):e2548. PMID: 18648548; PMCID: PMC2481296.
    46. Liang J, Wan M, Zhang Y, Gu P, Xin H, Jung SY, Qin J, Wong J, Cooney AJ, Liu D, Songyang Z. Nanog and Oct4 associate with unique transcriptional repression complexes in embryonic stem cells. Nat Cell Biol. 2008 Jun; 10(6):731-9. PMID: 18454139.
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    47. Reddy P, Liu L, Adhikari D, Jagarlamudi K, Rajareddy S, Shen Y, Du C, Tang W, Hämäläinen T, Peng SL, Lan ZJ, Cooney AJ, Huhtaniemi I, Liu K. Oocyte-specific deletion of Pten causes premature activation of the primordial follicle pool. Science. 2008 Feb 1; 319(5863):611-3. PMID: 18239123.
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    48. Mullen EM, Gu P, Cooney AJ. Nuclear Receptors in Regulation of Mouse ES Cell Pluripotency and Differentiation. PPAR Res. 2007; 2007:61563. PMID: 18274628; PMCID: PMC2233893.
    49. Benoit G, Cooney A, Giguere V, Ingraham H, Lazar M, Muscat G, Perlmann T, Renaud JP, Schwabe J, Sladek F, Tsai MJ, Laudet V. International Union of Pharmacology. LXVI. Orphan nuclear receptors. Pharmacol Rev. 2006 Dec; 58(4):798-836. PMID: 17132856.
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    50. García-Becerra R, Borja-Cacho E, Cooney AJ, Smith CL, Lemus AE, Pérez-Palacios G, Larrea F. Synthetic 19-nortestosterone derivatives as estrogen receptor alpha subtype-selective ligands induce similar receptor conformational changes and steroid receptor coactivator recruitment than natural estrogens. J Steroid Biochem Mol Biol. 2006 May; 99(2-3):108-14. PMID: 16616843.
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    51. Chung AC, Xu X, Niederreither KA, Cooney AJ. Loss of orphan nuclear receptor GCNF function disrupts forebrain development and the establishment of the isthmic organizer. Dev Biol. 2006 May 1; 293(1):13-24. PMID: 16530751.
      View in: PubMed
    52. Gu P, LeMenuet D, Chung AC, Mancini M, Wheeler DA, Cooney AJ. Orphan nuclear receptor GCNF is required for the repression of pluripotency genes during retinoic acid-induced embryonic stem cell differentiation. Mol Cell Biol. 2005 Oct; 25(19):8507-19. PMID: 16166633; PMCID: PMC1265758.
    53. Raviscioni M, Gu P, Sattar M, Cooney AJ, Lichtarge O. Correlated evolutionary pressure at interacting transcription factors and DNA response elements can guide the rational engineering of DNA binding specificity. J Mol Biol. 2005 Jul 15; 350(3):402-15. PMID: 15946684.
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    54. Gu P, Morgan DH, Sattar M, Xu X, Wagner R, Raviscioni M, Lichtarge O, Cooney AJ. Evolutionary trace-based peptides identify a novel asymmetric interaction that mediates oligomerization in nuclear receptors. J Biol Chem. 2005 Sep 9; 280(36):31818-29. PMID: 15994320.
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    55. Gu P, Goodwin B, Chung AC, Xu X, Wheeler DA, Price RR, Galardi C, Peng L, Latour AM, Koller BH, Gossen J, Kliewer SA, Cooney AJ. Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol. 2005 May; 25(9):3492-505. PMID: 15831456; PMCID: PMC1084298.
    56. Hummelke GC, Cooney AJ. Reciprocal regulation of the mouse protamine genes by the orphan nuclear receptor germ cell nuclear factor and CREMtau. Mol Reprod Dev. 2004 Aug; 68(4):394-407. PMID: 15236322.
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    57. Lan ZJ, Xu X, Cooney AJ. Differential oocyte-specific expression of Cre recombinase activity in GDF-9-iCre, Zp3cre, and Msx2Cre transgenic mice. Biol Reprod. 2004 Nov; 71(5):1469-74. PMID: 15215191.
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    58. García-Becerra R, Cooney AJ, Borja-Cacho E, Lemus AE, Pérez-Palacios G, Larrea F. Comparative evaluation of androgen and progesterone receptor transcription selectivity indices of 19-nortestosterone-derived progestins. J Steroid Biochem Mol Biol. 2004 Jun; 91(1-2):21-7. PMID: 15261304.
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    59. Gibbs RA, Weinstock GM, Metzker ML, Muzny DM, Sodergren EJ, Scherer S, Scott G, Steffen D, Worley KC, Burch PE, Okwuonu G, Hines S, Lewis L, DeRamo C, Delgado O, Dugan-Rocha S, Miner G, Morgan M, Hawes A, Gill R. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Nature. 2004 Apr 1; 428(6982):493-521. PMID: 15057822.
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    60. Zhang Z, Burch PE, Cooney AJ, Lanz RB, Pereira FA, Wu J, Gibbs RA, Weinstock G, Wheeler DA. Genomic analysis of the nuclear receptor family: new insights into structure, regulation, and evolution from the rat genome. Genome Res. 2004 Apr; 14(4):580-90. PMID: 15059999; PMCID: PMC383302.
    61. Lan ZJ, Xu X, Cooney AJ. Generation of a germ cell nuclear factor conditional allele in mice. Genesis. 2003 Dec; 37(4):172-9. PMID: 14666510.
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    62. Lan ZJ, Gu P, Xu X, Jackson KJ, DeMayo FJ, O'Malley BW, Cooney AJ. GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility. EMBO J. 2003 Aug 15; 22(16):4070-81. PMID: 12912906; PMCID: PMC175795.
    63. Chung AC, Cooney AJ. The varied roles of nuclear receptors during vertebrate embryonic development. Nucl Recept Signal. 2003; 1:e007. PMID: 16604179; PMCID: PMC1402219.
    64. Lan ZJ, Gu P, Xu X, Cooney AJ. Expression of the orphan nuclear receptor, germ cell nuclear factor, in mouse gonads and preimplantation embryos. Biol Reprod. 2003 Jan; 68(1):282-9. PMID: 12493724.
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    65. García-Becerra R, Borja-Cacho E, Cooney AJ, Jackson KJ, Lemus AE, Pérez-Palacios G, Larrea F. The intrinsic transcriptional estrogenic activity of a non-phenolic derivative of levonorgestrel is mediated via the estrogen receptor-alpha. J Steroid Biochem Mol Biol. 2002 Nov; 82(4-5):333-41. PMID: 12589940.
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    66. Kubli-Garfias C, Vázquez R, Cooney AJ, Larrea F. Ab initio electronic structure of the progestogen norethisterone and its 5 alpha-derivatives. J Steroid Biochem Mol Biol. 2002 Nov; 82(4-5):385-91. PMID: 12589946.
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    67. Lan ZJ, Chung AC, Xu X, DeMayo FJ, Cooney AJ. The embryonic function of germ cell nuclear factor is dependent on the DNA binding domain. J Biol Chem. 2002 Dec 27; 277(52):50660-7. PMID: 12381721.
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    68. Tubb B, Mulholland DJ, Vogl W, Lan ZJ, Niederberger C, Cooney A, Bryan J. Testis fascin (FSCN3): a novel paralog of the actin-bundling protein fascin expressed specifically in the elongate spermatid head. Exp Cell Res. 2002 Apr 15; 275(1):92-109. PMID: 11925108.
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    69. Choi J, Nannenga B, Demidov ON, Bulavin DV, Cooney A, Brayton C, Zhang Y, Mbawuike IN, Bradley A, Appella E, Donehower LA. Mice deficient for the wild-type p53-induced phosphatase gene (Wip1) exhibit defects in reproductive organs, immune function, and cell cycle control. Mol Cell Biol. 2002 Feb; 22(4):1094-105. PMID: 11809801; PMCID: PMC134641.
    70. Chung AC, Cooney AJ. Germ cell nuclear factor. Int J Biochem Cell Biol. 2001 Dec; 33(12):1141-6. PMID: 11606249.
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    71. Hummelke GC, Cooney AJ. Germ cell nuclear factor is a transcriptional repressor essential for embryonic development. Front Biosci. 2001 Oct 1; 6:D1186-91. PMID: 11578963.
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    72. Fuhrmann G, Chung AC, Jackson KJ, Hummelke G, Baniahmad A, Sutter J, Sylvester I, Schöler HR, Cooney AJ. Mouse germline restriction of Oct4 expression by germ cell nuclear factor. Dev Cell. 2001 Sep; 1(3):377-87. PMID: 11702949.
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    73. Larrea F, García-Becerra R, Lemus AE, García GA, Pérez-Palacios G, Jackson KJ, Coleman KM, Dace R, Smith CL, Cooney AJ. A-ring reduced metabolites of 19-nor synthetic progestins as subtype selective agonists for ER alpha. Endocrinology. 2001 Sep; 142(9):3791-9. PMID: 11517155.
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    74. Larrea F, Garci A-Becerra R, Lemus AE, Garci A GA, Pe Rez-Palacios G, Jackson KJ, Coleman KM, Dace R, Smith CL, Cooney AJ. A-Ring Reduced Metabolites of 19-nor Synthetic Progestins as Subtype Selective Agonists for ER?. Endocrinology. 2001 Sep 01; 142(9):3791-3799. PMID: 28201397.
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    75. Cooney AJ, Lee CT, Lin SC, Tsai SY, Tsai MJ. Physiological function of the orphans GCNF and COUP-TF. Trends Endocrinol Metab. 2001 Aug; 12(6):247-51. PMID: 11445441.
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    76. Chung AC, Katz D, Pereira FA, Jackson KJ, DeMayo FJ, Cooney AJ, O'Malley BW. Loss of orphan receptor germ cell nuclear factor function results in ectopic development of the tail bud and a novel posterior truncation. Mol Cell Biol. 2001 Jan; 21(2):663-77. PMID: 11134352; PMCID: PMC86646.
    77. Lemus AE, Zaga V, Santillán R, García GA, Grillasca I, Damián-Matsumura P, Jackson KJ, Cooney AJ, Larrea F, Pérez-Palacios G. The oestrogenic effects of gestodene, a potent contraceptive progestin, are mediated by its A-ring reduced metabolites. J Endocrinol. 2000 Jun; 165(3):693-702. PMID: 10828854.
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    78. Jaimez R, Cooney A, Jackson K, Lemus AE, Lemini C, Cárdenas M, García R, Silva G, Larrea F. In vivo estrogen bioactivities and in vitro estrogen receptor binding and transcriptional activities of anticoagulant synthetic 17beta-aminoestrogens. J Steroid Biochem Mol Biol. 2000 May; 73(1-2):59-66. PMID: 10822025.
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    79. Hummelke GC, Meistrich ML, Cooney AJ. Mouse protamine genes are candidate targets for the novel orphan nuclear receptor, germ cell nuclear factor. Mol Reprod Dev. 1998 Aug; 50(4):396-405. PMID: 9669523.
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    80. Cooney AJ, Hummelke GC, Herman T, Chen F, Jackson KJ. Germ cell nuclear factor is a response element-specific repressor of transcription. Biochem Biophys Res Commun. 1998 Apr 7; 245(1):94-100. PMID: 9535790.
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    81. Agoulnik IY, Cho Y, Niederberger C, Kieback DG, Cooney AJ. Cloning, expression analysis and chromosomal localization of the human nuclear receptor gene GCNF. FEBS Lett. 1998 Mar 6; 424(1-2):73-8. PMID: 9537518.
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    82. Cooney AJ. Use of T4 DNA polymerase to create cohesive termini in PCR products for subcloning and site-directed mutagenesis. Biotechniques. 1998 Jan; 24(1):30, 32, 34. PMID: 9454946.
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    83. Katz D, Niederberger C, Slaughter GR, Cooney AJ. Characterization of germ cell-specific expression of the orphan nuclear receptor, germ cell nuclear factor. Endocrinology. 1997 Oct; 138(10):4364-72. PMID: 9322952.
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    84. Leng X, Cooney AJ, Tsai SY, Tsai MJ. Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression. Mol Cell Biol. 1996 May; 16(5):2332-40. PMID: 8628300; PMCID: PMC231221.
    85. Feng JQ, Chen D, Cooney AJ, Tsai MJ, Harris MA, Tsai SY, Feng M, Mundy GR, Harris SE. The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptor. J Biol Chem. 1995 Nov 24; 270(47):28364-73. PMID: 7499338.
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    86. Chen F, Cooney AJ, Wang Y, Law SW, O'Malley BW. Cloning of a novel orphan receptor (GCNF) expressed during germ cell development. Mol Endocrinol. 1994 Oct; 8(10):1434-44. PMID: 7854358.
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    87. Beekman JM, Cooney AJ, Elliston JF, Tsai SY, Tsai MJ. A rapid one-step method to purify baculovirus-expressed human estrogen receptor to be used in the analysis of the oxytocin promoter. Gene. 1994 Sep 2; 146(2):285-9. PMID: 8076833.
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    88. Liu X, Ge R, Westmoreland S, Cooney AJ, Tsai SY, Tsai MJ, Ricciardi RP. Negative regulation by the R2 element of the MHC class I enhancer in adenovirus-12 transformed cells correlates with high levels of COUP-TF binding. Oncogene. 1994 Aug; 9(8):2183-90. PMID: 8036004.
      View in: PubMed
    89. Zeng Z, Allan GF, Thaller C, Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Detection of potential ligands for nuclear receptors in cellular extracts. Endocrinology. 1994 Jul; 135(1):248-52. PMID: 8013359.
      View in: PubMed
    90. Burbach JP, Lopes da Silva S, Cox JJ, Adan RA, Cooney AJ, Tsai MJ, Tsai SY. Repression of estrogen-dependent stimulation of the oxytocin gene by chicken ovalbumin upstream promoter transcription factor I. J Biol Chem. 1994 May 27; 269(21):15046-53. PMID: 8195142.
      View in: PubMed
    91. Qiu Y, Cooney AJ, Kuratani S, DeMayo FJ, Tsai SY, Tsai MJ. Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4451-5. PMID: 8183930; PMCID: PMC43803.
    92. Lutz B, Kuratani S, Cooney AJ, Wawersik S, Tsai SY, Eichele G, Tsai MJ. Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons. Development. 1994 Jan; 120(1):25-36. PMID: 8119130.
      View in: PubMed
    93. Cooney AJ, Leng X, Tsai SY, O'Malley BW, Tsai MJ. Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem. 1993 Feb 25; 268(6):4152-60. PMID: 8382695.
      View in: PubMed
    94. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol. 1992 Sep; 12(9):4153-63. PMID: 1324415; PMCID: PMC360317.
    95. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat. J Virol. 1991 Jun; 65(6):2853-60. PMID: 2033658; PMCID: PMC240909.
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