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RANDALL A. PRINCE

TitleProfessor
InstitutionUniversity of Houston College of Pharmacy
DepartmentClinical Sciences & Administration
AddressTexas Medical Center Campus, Room 307
1441 Moursund
Houston TX 77030
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    1. Rolston KV, Jamal MA, Nesher L, Shelburne SA, Raad I, Prince RA. In vitro activity of ceftaroline and comparator agents against Gram-positive and Gram-negative clinical isolates from cancer patients. Int J Antimicrob Agents. 2017 Feb 28. PMID: 28257904.
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    2. Rolston KV, Wang W, Nesher L, Smith JR, Rybak MJ, Prince RA. Time-kill determination of the bactericidal activity of telavancin and vancomycin against clinical methicillin-resistant Staphylococcus aureus isolates from cancer patients. Diagn Microbiol Infect Dis. 2016 Dec 16. PMID: 28109549.
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    3. Aitken SL, Tarrand JJ, Deshpande LM, Tverdek FP, Jones AL, Shelburne SA, Prince RA, Bhatti MM, Rolston KV, Jones RN, Castanheira M, Chemaly RF. High Rates of Nonsusceptibility to Ceftazidime-avibactam and Identification of New Delhi Metallo-?-lactamase Production in Enterobacteriaceae Bloodstream Infections at a Major Cancer Center. Clin Infect Dis. 2016 Oct 1; 63(7):954-8. PMID: 27313265.
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    4. Rolston KV, Wang W, Nesher L, Shelburne SA, Prince RA. In vitro activity of dalbavancin and five comparator agents against common and uncommon Gram-positive organisms isolated from cancer patients. J Antibiot (Tokyo). 2016 May; 69(5):381-7. PMID: 26626876.
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    5. Kassamali Z, Prince RA, Danziger LH, Rotschafer JC, Rhomberg PR, Jones RN. Microbiological Assessment of Polymyxin B Components Tested Alone and in Combination. Antimicrob Agents Chemother. 2015 Dec; 59(12):7823-5. PMID: 26392511.
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    6. Rolston K, Wang W, Nesher L, Coyle E, Shelburne S, Prince RA. In vitro activity of telavancin compared with vancomycin and linezolid against Gram-positive organisms isolated from cancer patients. J Antibiot (Tokyo). 2014 Jul; 67(7):505-9. PMID: 24824818.
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    7. Kassamali Z, Rotschafer JC, Jones RN, Prince RA, Danziger LH. Reply to Nation et al. Clin Infect Dis. 2013 Dec; 57(11):1657-8. PMID: 23934308.
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    8. Kassamali Z, Rotschafer JC, Jones RN, Prince RA, Danziger LH. Polymyxins: wisdom does not always come with age. Clin Infect Dis. 2013 Sep; 57(6):877-83. PMID: 23728146.
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    9. Rolston KV, Kapadia M, Tarrand J, Coyle E, Prince RA. Spectrum of gram-positive bacteraemia and in vitro activities of daptomycin, linezolid and vancomycin against organisms isolated from cancer patients. Int J Antimicrob Agents. 2013 Jun; 41(6):516-20. PMID: 23481658.
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    10. Lewis RE, Albert NP, Liao G, Wang W, Prince RA, Kontoyiannis DP. High-dose induction liposomal amphotericin B followed by de-escalation is effective in experimental Aspergillus terreus pneumonia. J Antimicrob Chemother. 2013 May; 68(5):1148-51. PMID: 23349440.
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    11. Chaftari AM, Hachem RY, Ramos E, Kassis C, Campo M, Jiang Y, Prince RA, Wang W, Raad II. Comparison of posaconazole versus weekly amphotericin B lipid complex for the prevention of invasive fungal infections in hematopoietic stem-cell transplantation. Transplantation. 2012 Aug 15; 94(3):302-8. PMID: 22814329.
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    12. Lewis RE, Liao G, Wang W, Prince RA, Kontoyiannis DP. Voriconazole pre-exposure selects for breakthrough mucormycosis in a mixed model of Aspergillus fumigatus-Rhizopus oryzae pulmonary infection. Virulence. 2011 Jul-Aug; 2(4):348-55. PMID: 21788730.
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    13. Lewis RE, Liao G, Hou J, Prince RA, Kontoyiannis DP. Comparative in vivo dose-dependent activity of caspofungin and anidulafungin against echinocandin-susceptible and -resistant Aspergillus fumigatus. J Antimicrob Chemother. 2011 Jun; 66(6):1324-31. PMID: 21486855.
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    14. Mihu CN, Rhomberg PR, Jones RN, Coyle E, Prince RA, Rolston KV. Escherichia coli resistance to quinolones at a comprehensive cancer center. Diagn Microbiol Infect Dis. 2010 Jul; 67(3):266-9. PMID: 20471765.
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    15. Yuan Z, Ledesma KR, Singh R, Hou J, Prince RA, Tam VH. Quantitative assessment of combination antimicrobial therapy against multidrug-resistant bacteria in a murine pneumonia model. J Infect Dis. 2010 Mar 15; 201(6):889-97. PMID: 20156065.
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    16. Lewis RE, Albert ND, Liao G, Hou J, Prince RA, Kontoyiannis DP. Comparative pharmacodynamics of amphotericin B lipid complex and liposomal amphotericin B in a murine model of pulmonary mucormycosis. Antimicrob Agents Chemother. 2010 Mar; 54(3):1298-304. PMID: 20038620; PMCID: PMC2826015.
    17. Singh R, Ledesma KR, Chang KT, Hou JG, Prince RA, Tam VH. Pharmacodynamics of moxifloxacin against a high inoculum of Escherichia coli in an in vitro infection model. J Antimicrob Chemother. 2009 Sep; 64(3):556-62. PMID: 19589810.
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    18. Tam VH, Hou J, Kwa AL, Prince RA. Comment on: Development and validation of a reversed-phase high-performance liquid chromatography assay for polymyxin B in human plasma. J Antimicrob Chemother. 2009 Mar; 63(3):627-8; author reply 628-9. PMID: 19022780.
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    19. Lim TP, Ledesma KR, Chang KT, Hou JG, Kwa AL, Nikolaou M, Quinn JP, Prince RA, Tam VH. Quantitative assessment of combination antimicrobial therapy against multidrug-resistant Acinetobacter baumannii. Antimicrob Agents Chemother. 2008 Aug; 52(8):2898-904. PMID: 18505848; PMCID: PMC2493134.
    20. Vemulakonda GA, Hariprasad SM, Mieler WF, Prince RA, Shah GK, Van Gelder RN. Aqueous and vitreous concentrations following topical administration of 1% voriconazole in humans. Arch Ophthalmol. 2008 Jan; 126(1):18-22. PMID: 18195213.
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    21. Andes D, Diekema DJ, Pfaller MA, Prince RA, Marchillo K, Ashbeck J, Hou J. In vivo pharmacodynamic characterization of anidulafungin in a neutropenic murine candidiasis model. Antimicrob Agents Chemother. 2008 Feb; 52(2):539-50. PMID: 18070979; PMCID: PMC2224754.
    22. Kwa AL, Lim TP, Low JG, Hou J, Kurup A, Prince RA, Tam VH. Pharmacokinetics of polymyxin B1 in patients with multidrug-resistant Gram-negative bacterial infections. Diagn Microbiol Infect Dis. 2008 Feb; 60(2):163-7. PMID: 17916420.
      View in: PubMed
    23. Lewis RE, Liao G, Hou J, Chamilos G, Prince RA, Kontoyiannis DP. Comparative analysis of amphotericin B lipid complex and liposomal amphotericin B kinetics of lung accumulation and fungal clearance in a murine model of acute invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2007 Apr; 51(4):1253-8. PMID: 17261624; PMCID: PMC1855500.
    24. Lewis RE, Chamilos G, Prince RA, Kontoyiannis DP. Pretreatment with empty liposomes attenuates the immunopathology of invasive pulmonary aspergillosis in corticosteroid-immunosuppressed mice. Antimicrob Agents Chemother. 2007 Mar; 51(3):1078-81. PMID: 17194825; PMCID: PMC1803112.
    25. Hariprasad SM, Shah GK, Mieler WF, Feiner L, Blinder KJ, Holekamp NM, Gao H, Prince RA. Vitreous and aqueous penetration of orally administered moxifloxacin in humans. Arch Ophthalmol. 2006 Feb; 124(2):178-82. PMID: 16476886.
      View in: PubMed
    26. Wiederhold NP, Tam VH, Chi J, Prince RA, Kontoyiannis DP, Lewis RE. Pharmacodynamic activity of amphotericin B deoxycholate is associated with peak plasma concentrations in a neutropenic murine model of invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2006 Feb; 50(2):469-73. PMID: 16436698; PMCID: PMC1366892.
    27. Lewis RE, Wiederhold NP, Prince RA, Kontoyiannis DP. In vitro pharmacodynamics of rapid versus continuous infusion of amphotericin B deoxycholate against Candida species in the presence of human serum albumin. J Antimicrob Chemother. 2006 Feb; 57(2):288-93. PMID: 16387749.
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    28. Lewis RE, Wiederhold NP, Lionakis MS, Prince RA, Kontoyiannis DP. Frequency and species distribution of gliotoxin-producing Aspergillus isolates recovered from patients at a tertiary-care cancer center. J Clin Microbiol. 2005 Dec; 43(12):6120-2. PMID: 16333108; PMCID: PMC1317213.
    29. Wiederhold NP, Kontoyiannis DP, Prince RA, Lewis RE. Attenuation of the activity of caspofungin at high concentrations against candida albicans: possible role of cell wall integrity and calcineurin pathways. Antimicrob Agents Chemother. 2005 Dec; 49(12):5146-8. PMID: 16304189; PMCID: PMC1315970.
    30. Hariprasad SM, Shah GK, Chi J, Prince RA. Determination of aqueous and vitreous concentration of moxifloxacin 0.5% after delivery via a dissolvable corneal collagen shield device. J Cataract Refract Surg. 2005 Nov; 31(11):2142-6. PMID: 16412929.
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    31. Walker P, Neuhauser MN, Tam VH, Willey JS, Palmer JL, Bruera E, Prince RA. Subcutaneous administration of cefepime. J Pain Symptom Manage. 2005 Aug; 30(2):170-4. PMID: 16125032.
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    32. Prince RA, Hoffman CJ, Scanlan RM, Mayberry JC. The distinct and secondary harmful effect of pelvic and extremity injury on the outcome of laparotomy for trauma. J Surg Res. 2005 Mar; 124(1):3-8. PMID: 15734472.
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    33. Lewis RE, Wiederhold NP, Chi J, Han XY, Komanduri KV, Kontoyiannis DP, Prince RA. Detection of gliotoxin in experimental and human aspergillosis. Infect Immun. 2005 Jan; 73(1):635-7. PMID: 15618207; PMCID: PMC538950.
    34. Hariprasad SM, Blinder KJ, Shah GK, Apte RS, Rosenblatt B, Holekamp NM, Thomas MA, Mieler WF, Chi J, Prince RA. Penetration pharmacokinetics of topically administered 0.5% moxifloxacin ophthalmic solution in human aqueous and vitreous. Arch Ophthalmol. 2005 Jan; 123(1):39-44. PMID: 15642810.
      View in: PubMed
    35. Wiederhold NP, Kontoyiannis DP, Chi J, Prince RA, Tam VH, Lewis RE. Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: evidence of concentration-dependent activity. J Infect Dis. 2004 Oct 15; 190(8):1464-71. PMID: 15378439.
      View in: PubMed
    36. Hsue G, Napier JT, Prince RA, Chi J, Hospenthal DR. Treatment of meningeal coccidioidomycosis with caspofungin. J Antimicrob Chemother. 2004 Jul; 54(1):292-4. PMID: 15190025.
      View in: PubMed
    37. Hariprasad SM, Mieler WE, Shah GK, Blinder KJ, Apte RS, Holekamp NM, Thomas MA, Chi J, Prince RA. Human intraocular penetration pharmacokinetics of moxifloxacin 0.5% via topical and collagen shield routes of administration. Trans Am Ophthalmol Soc. 2004; 102:149-55; discussion 155-7. PMID: 15747753; PMCID: PMC1280095.
    38. Hariprasad SM, Mieler WF, Holz ER, Gao H, Kim JE, Chi J, Prince RA. Determination of vitreous, aqueous, and plasma concentration of orally administered voriconazole in humans. Arch Ophthalmol. 2004 Jan; 122(1):42-7. PMID: 14718293.
      View in: PubMed
    39. Lewis RE, Kontoyiannis DP, Darouiche RO, Raad II, Prince RA. Antifungal activity of amphotericin B, fluconazole, and voriconazole in an in vitro model of Candida catheter-related bloodstream infection. Antimicrob Agents Chemother. 2002 Nov; 46(11):3499-505. PMID: 12384356; PMCID: PMC128760.
    40. Lewis RE, Prince RA, Chi J, Kontoyiannis DP. Itraconazole preexposure attenuates the efficacy of subsequent amphotericin B therapy in a murine model of acute invasive pulmonary aspergillosis. Antimicrob Agents Chemother. 2002 Oct; 46(10):3208-14. PMID: 12234846; PMCID: PMC128771.
    41. Kontoyiannis DP, Lewis RE, Sagar N, May G, Prince RA, Rolston KV. Itraconazole-amphotericin B antagonism in Aspergillus fumigatus: an E-test-based strategy. Antimicrob Agents Chemother. 2000 Oct; 44(10):2915-8. PMID: 10991890; PMCID: PMC90181.
    42. Baldwin JC, Miller CC, Prince RA, Espada R. Chest radiograph heterogeneity predicts functional improvement with volume reduction surgery. Ann Thorac Surg. 2000 Oct; 70(4):1208-11. PMID: 11081872.
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    43. Prince RA, Lucas DS, Fox JL. Effect of a dual-lumen peripheral catheter on the delivery of known incompatible medications. Ann Pharmacother. 1998 Sep; 32(9):875-7. PMID: 9762372.
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    44. Tugwood JD, Holden PR, James NH, Prince RA, Roberts RA. A peroxisome proliferator-activated receptor-alpha (PPARalpha) cDNA cloned from guinea-pig liver encodes a protein with similar properties to the mouse PPARalpha: implications for species differences in responses to peroxisome proliferators. Arch Toxicol. 1998 Feb; 72(3):169-77. PMID: 9520140.
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    45. Griver AR, Prince RA, Darouiche RO. A simple method for administering vancomycin in the spinal cord injured population. Arch Phys Med Rehabil. 1997 May; 78(5):459-62. PMID: 9161361.
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    46. Anaissie EJ, Kontoyiannis DP, Huls C, Vartivarian SE, Karl C, Prince RA, Bosso J, Bodey GP. Safety, plasma concentrations, and efficacy of high-dose fluconazole in invasive mold infections. J Infect Dis. 1995 Aug; 172(2):599-602. PMID: 7622915.
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    47. Mack JL, File KM, Horwitz JE, Prince RA. The effect of urgency on patient satisfaction and future emergency department choice. Health Care Manage Rev. 1995; 20(2):7-15. PMID: 7607888.
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    48. Mack JL, File KM, Horwitz JE, Prince RA. Factors associated with emergency room choice among Medicare patients. J Ambul Care Mark. 1995; 6(1):45-58. PMID: 10170370.
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    49. Bosso JA, Prince RA, Fox JL. Compatibility of ondansetron hydrochloride with fluconazole, ceftazidime, aztreonam, and cefazolin sodium under simulated Y-site conditions. Am J Hosp Pharm. 1994 Feb 1; 51(3):389-91. PMID: 8160696.
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    50. Green S, Issemann I, Tugwood JD, Prince RA, Aldridge TC. Delineating peroxisome proliferator action to improve human risk assessment. Prog Clin Biol Res. 1994; 387:311-33. PMID: 7972256.
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    51. Issemann I, Prince RA, Tugwood JD, Green S. The peroxisome proliferator-activated receptor:retinoid X receptor heterodimer is activated by fatty acids and fibrate hypolipidaemic drugs. J Mol Endocrinol. 1993 Aug; 11(1):37-47. PMID: 8240670.
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    52. Huls CE, Prince RA, Seilheimer DK, Bosso JA. Pharmacokinetics of cefepime in cystic fibrosis patients. Antimicrob Agents Chemother. 1993 Jul; 37(7):1414-6. PMID: 8363368; PMCID: PMC187985.
    53. Issemann I, Prince RA, Tugwood JD, Green S. The retinoid X receptor enhances the function of the peroxisome proliferator activated receptor. Biochimie. 1993; 75(3-4):251-6. PMID: 8389594.
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    54. Issemann I, Prince R, Tugwood J, Green S. A role for fatty acids and liver fatty acid binding protein in peroxisome proliferation? Biochem Soc Trans. 1992 Nov; 20(4):824-7. PMID: 1487072.
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    55. Bosso JA, Prince RA, Fox JL. Stability of ondansetron hydrochloride in injectable solutions at -20, 5, and 25 degrees C. Am J Hosp Pharm. 1992 Sep; 49(9):2223-5. PMID: 1388000.
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    56. Jackson GH, Middleton P, Prince R, Bown N, Kernahan J, Reid MM. Philadelphia positive acute leukaemia with minor breakpoint cluster rearrangement may be a stem cell disease. Br J Haematol. 1992 May; 81(1):77-80. PMID: 1520629.
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    57. Middleton PG, Prince RA, Williamson IK, Taylor PR, Reid MM, Jackson GH, Katz F, Chessells JM, Proctor SJ. Alpha interferon gene deletions in adults, children and infants with acute lymphoblastic leukemia. Leukemia. 1991 Aug; 5(8):680-2. PMID: 1886420.
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    58. Bosso JA, Prince RA. Anti-anaerobic antimicrobial agents: cefoxitin, cefotetan, clindamycin, and metronidazole. Tex Heart Inst J. 1990; 17(2):77-85. PMID: 15227388; PMCID: PMC326456.
    59. Prince RA, Casabar E, Adair CG, Wexler DB, Lettieri J, Kasik JE. Effect of quinolone antimicrobials on theophylline pharmacokinetics. J Clin Pharmacol. 1989 Jul; 29(7):650-4. PMID: 2760258.
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    60. Barriere SL, Dudley MN, Kowalsky SF, Kreter B, Polk RE, Prince RA, Tartaglione T. The role of the pharmacist in antimicrobial agent therapy. J Infect Dis. 1989 Mar; 159(3):593-4. PMID: 2915174.
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    61. Prince RA, Johnson JA, Weinberger MM. Influence of endotoxin-induced fever on the pharmacokinetics of theophylline in the rabbit model. Pharmacotherapy. 1989; 9(4):240-4. PMID: 2671956.
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    62. Fick RB, Alexander MR, Prince RA, Kasik JE. Penetration of cefotaxime into respiratory secretions. Antimicrob Agents Chemother. 1987 May; 31(5):815-7. PMID: 3606080; PMCID: PMC174841.
    63. Prince RA. Antimicrobial update. Drug Intell Clin Pharm. 1986 Jul-Aug; 20(7-8):583-6. PMID: 3527637.
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    64. Perry PJ, Alexander B, Prince RA, Dunner FJ. The utility of a single-point dosing protocol for predicting steady-state lithium levels. Br J Psychiatry. 1986 Apr; 148:401-5. PMID: 3089352.
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    65. Perry PJ, Browne JL, Prince RA, Alexander B, Tsuang MT. Effects of smoking on nortriptyline plasma concentrations in depressed patients. Ther Drug Monit. 1986; 8(3):279-84. PMID: 3750370.
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    66. Prince RA, Pincheira JC, Mason EE, Printen KJ. Influence of bariatric surgery on erythromycin absorption. J Clin Pharmacol. 1984 Nov-Dec; 24(11-12):523-7. PMID: 6511992.
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    67. Perry PJ, Alexander B, Prince RA, Dunner FJ. Prospective evaluation of two lithium maintenance dose schedules. J Clin Psychopharmacol. 1984 Oct; 4(5):242-6. PMID: 6490961.
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    68. Taylor JW, Prince RA. Comparison of multiple-point methods for estimating phenytoin maintenance dose requirements. Am J Hosp Pharm. 1984 Feb; 41(2):326-9. PMID: 6702844.
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    69. Prince RA, Villar LA. Side-effect profiles of newer-generation cephalosporins. Drug Intell Clin Pharm. 1983 Sep; 17(9):656-7. PMID: 6617488.
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    70. Perry PJ, Prince RA, Alexander B, Dunner FJ. Prediction of lithium maintenance doses using a single point prediction protocol. J Clin Psychopharmacol. 1983 Feb; 3(1):13-7. PMID: 6833518.
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    71. Mathis JW, Prince RA, Weinberger MM, McElnay JC. Effect of tetracycline hydrochloride on theophylline kinetics. Clin Pharm. 1982 Sep-Oct; 1(5):446-8. PMID: 7184676.
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    72. LeFrock JL, Prince RA, Leff RD. Mechanism of action, antimicrobial activity, pharmacology, adverse effects, and clinical efficacy of cefotaxime. Pharmacotherapy. 1982 Jul-Aug; 2(4):174-84. PMID: 6302641.
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    73. Prince RA, Harris JM, Maroc JA. Comparative trial of benzoyl peroxide versus benzoyl peroxide with urea in inflammatory acne. Cutis. 1982 Jun; 29(6):638-40, 644-5. PMID: 6213380.
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    74. Molavi A, LeFrock JL, Prince RA. Metronidazole. Med Clin North Am. 1982 Jan; 66(1):121-33. PMID: 7038323.
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    75. LeFrock JL, Molavi A, Prince RA. Clindamycin. Med Clin North Am. 1982 Jan; 66(1):103-20. PMID: 7038322.
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    76. Prince RA, Wing DS, Weinberger MM, Hendeles LS, Riegelman S. Effect of erythromycin on theophylline kinetics. J Allergy Clin Immunol. 1981 Dec; 68(6):427-31. PMID: 7031111.
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    77. Prince RA, Cassel DH, Hepler CD, Wilson JL, Jones ME, Feldick HG, Helling DK. Comparative trial of two sulfisoxazole regimens in acute urinary tract infection. Drug Intell Clin Pharm. 1981 Nov; 15(11):863-6. PMID: 7028439.
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    78. Richards ML, Prince RA, Kenaley KA, Johnson JA, LeFrock JL. Antimicrobial penetration into cerebrospinal fluid. Drug Intell Clin Pharm. 1981 May; 15(5):341-68. PMID: 7023900.
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    79. Prince RA, Busch DA, Hepler CD, Feldick HG. Clinical trial of topical erythromycin in inflammatory acne. Drug Intell Clin Pharm. 1981 May; 15(5):372-6. PMID: 6456140.
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    80. Pinchiera JC, Prince RA, Mason EE. Effect of bariatric surgery on erythromycin absorption. Am J Hosp Pharm. 1981 Feb; 38(2):232. PMID: 7211889.
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    81. Hepler CD, Prince RA. Use of simulation to develop multiple-dose regimens for drugs exhibiting nonlinear elimination kinetics. Am J Hosp Pharm. 1980 Dec; 37(12):1631-5. PMID: 7446538.
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    82. Prince RA, Ling MH, Hepler CD, Rainville EC, Kealey GP, Donta ST, LeFrock JL, Kowalsky SF. Factors associated with creatinine clearance changes following gentamicin therapy. Am J Hosp Pharm. 1980 Nov; 37(11):1489-95. PMID: 7211851.
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    83. Prince RA, Brown BT, Jacknowitz AI. Agranulocytosis associated with procainamide therapy--report of a case. Am J Hosp Pharm. 1977 Dec; 34(12):1362-5. PMID: 596390.
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    84. LeFrock JL, Joseph BK, Klainer AS, Gainer RB, Prince RA. Infectious arthritis resulting from Enterobacter cloacae and Enterobacter hafniae. Clin Pediatr (Phila). 1977 Sep; 16(9):838-9. PMID: 891089.
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    85. Jacknowitz AI, Le Frock JL, Prince RA. Nitrofurantoin polyneuropathy: report of two cases. Am J Hosp Pharm. 1977 Jul; 34(7):759-62. PMID: 888840.
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    86. Prince RA, Le Frock JL, Jacknowitz AI. Antimicrobial usage in patients with renal impairment. W V Med J. 1976 Jun; 72(6):130-4. PMID: 1064244.
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