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NEAL S KLEIMAN

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Cardiology
Address1709 Dryden Road, Suite 900
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hira RS, Vemulapalli S, Li Z, McCabe JM, Rumsfeld JS, Kapadia SR, Alam M, Jneid H, Don C, Reisman M, Virani SS, Kleiman NS. Trends and Outcomes of Off-Label Use of Transcatheter Aortic Valve Replacement: Insights From the NCDR STS/ACC TVT Registry. JAMA Cardiol. 2017 Jun 21. PMID: 28636718.
      View in: PubMed
    2. Ibrahim H, Kleiman NS. Platelet pathophysiology, pharmacology, and function in coronary artery disease. Coron Artery Dis. 2017 Jun 21. PMID: 28644213.
      View in: PubMed
    3. Kalra A, Reyes M, Yang EY, Little SH, Nabi F, Barker CM, Ramchandani M, Reul RM, Reardon MJ, Kleiman NS. Transcatheter Aortic Valve Replacement for Perceval Sutureless Aortic Valve Failure. J Invasive Cardiol. 2017 Jun; 29(6):E65-E66. PMID: 28570238.
      View in: PubMed
    4. Kalra A, Rehman H, Ramchandani M, Barker CM, Lawrie GM, Reul RM, Reardon MJ, Kleiman NS. Early Trifecta valve failure: Report of a cluster of cases from a tertiary care referral center. J Thorac Cardiovasc Surg. 2017 May 22. PMID: 28610762.
      View in: PubMed
    5. Deeb GM, Chetcuti SJ, Reardon MJ, Patel HJ, Grossman PM, Schreiber T, Forrest JK, Bajwa TK, O'Hair DP, Petrossian G, Robinson N, Katz S, Hartman A, Dauerman HL, Schmoker J, Khabbaz K, Watson DR, Yakubov SJ, Oh JK, Li S, Kleiman NS, Adams DH, Popma JJ. 1-Year Results in Patients Undergoing Transcatheter Aortic Valve Replacement With Failed Surgical Bioprostheses. JACC Cardiovasc Interv. 2017 May 22; 10(10):1034-1044. PMID: 28521921.
      View in: PubMed
    6. Khera S, Kolte D, Gupta T, Goldsweig A, Velagapudi P, Kalra A, Tang GHL, Aronow WS, Fonarow GC, Bhatt DL, Aronow HD, Kleiman NS, Reardon M, Gordon PC, Sharaf B, Abbott JD. Association Between Hospital Volume and 30-Day Readmissions Following Transcatheter Aortic Valve Replacement. JAMA Cardiol. 2017 May 11. PMID: 28494061.
      View in: PubMed
    7. Kleiman NS, Kleiman NJ. At Arms Length: Radiation Safety During Radial PCI. J Am Coll Cardiol. 2017 Mar 15. PMID: 28330795.
      View in: PubMed
    8. Kalra A, Rehman H, Khera S, Thyagarajan B, Bhatt DL, Kleiman NS, Yeh RW. New-Generation Coronary Stents: Current Data and Future Directions. Curr Atheroscler Rep. 2017 Mar; 19(3):14. PMID: 28220461.
      View in: PubMed
    9. O'Hair DP, Bajwa TK, Chetcuti SJ, Deeb GM, Stoler RC, Hebeler RF, Maini B, Mumtaz M, Kleiman NS, Reardon MJ, Li S, Adams DH, Watson DR, Yakubov SJ, Popma JJ, Petrossian G. One-Year Outcomes of Transcatheter Aortic Valve Replacement in Patients With End-Stage Renal Disease. Ann Thorac Surg. 2017 Feb 24. PMID: 28242075.
      View in: PubMed
    10. Gaudiani V, Deeb GM, Popma JJ, Adams DH, Gleason TG, Conte JV, Zorn GL, Hermiller JB, Chetcuti S, Mumtaz M, Yakubov SJ, Kleiman NS, Huang J, Reardon MJ. Causes of death from the randomized CoreValve US Pivotal High-Risk Trial. J Thorac Cardiovasc Surg. 2017 Feb 04. PMID: 28249691.
      View in: PubMed
    11. Kalra A, Bhatt DL, Kleiman NS. A 24-Month Interventional Cardiology Fellowship: Learning Motor Skills Through Blocked Repetition. JACC Cardiovasc Interv. 2017 Jan 23; 10(2):210-211. PMID: 28104222.
      View in: PubMed
    12. Kalra A, Reardon MJ, Kleiman NS. Optimizing Management of Patients With Atrial Fibrillation Following Transcatheter Aortic Valve Replacement: The Importance of Distinguishing Pre-Existing From New Onset Atrial Fibrillation. JACC Cardiovasc Interv. 2017 Jan 09; 10(1):101-103. PMID: 28057276.
      View in: PubMed
    13. Kalra A, Kleiman NS, Bhatt DL. Structural Heart Interventional Training: The Next Steps. JACC Cardiovasc Interv. 2016 Dec 26; 9(24):2581-2582. PMID: 28007209.
      View in: PubMed
    14. Stolker JM, Cohen DJ, Kennedy KF, Pencina MJ, Arnold SV, Kleiman NS, Spertus JA. Combining clinical and angiographic variables for estimating risk of target lesion revascularization after drug eluting stent placement. Cardiovasc Revasc Med. 2016 Dec 18. PMID: 28041858.
      View in: PubMed
    15. Reardon MJ, Kleiman NS, Adams DH, Yakubov SJ, Coselli JS, Deeb GM, O'Hair D, Gleason TG, Lee JS, Hermiller JB, Chetcuti S, Heiser J, Merhi W, Zorn GL, Tadros P, Robinson N, Petrossian G, Hughes GC, Harrison JK, Maini B, Mumtaz M, Conte JV, Resar JR, Aharonian V, Pfeffer T, Oh JK, Huang J, Popma JJ. Outcomes in the Randomized CoreValve US Pivotal High Risk Trial in Patients With a Society of Thoracic Surgeons Risk Score of 7% or Less. JAMA Cardiol. 2016 Nov 01; 1(8):945-949. PMID: 27541162.
      View in: PubMed
    16. Kleiman NS, Reardon MJ. Von Willebrand factor, paravalvular leak, and a new vista for TAVR. J Thorac Dis. 2016 Oct; 8(10):E1337-E1339. PMID: 27867621.
      View in: PubMed
    17. Kleiman NS, Maini BJ, Reardon MJ, Conte J, Katz S, Rajagopal V, Kauten J, Hartman A, McKay R, Hagberg R, Huang J, Popma J. Neurological Events Following Transcatheter Aortic Valve Replacement and Their Predictors: A Report From the CoreValve Trials. Circ Cardiovasc Interv. 2016 Sep; 9(9). PMID: 27601429.
      View in: PubMed
    18. Kleiman NS. The Last Detail: Platelets, Glycoprotein IIb/IIIa Antagonists, and Excipients. JACC Cardiovasc Interv. 2016 Aug 22; 9(16):1677-9. PMID: 27539686.
      View in: PubMed
    19. Kalra A, Bhatt DL, Pinto DS, Kirtane AJ, Kapadia SR, Makkar RR, Rihal CS, Kleiman NS, Cutlip DE. Accreditation and funding for a 24-month advanced interventional cardiology fellowship program: A call-to-action for optimal training of the next generation of interventionalists. Catheter Cardiovasc Interv. 2016 Nov 15; 88(6):1010-1015. PMID: 27515241.
      View in: PubMed
    20. Reardon MJ, Kleiman NS. Highway to the heart or one more for the road? The continued life of direct aortic access for transcatheter aortic valve replacement. J Thorac Cardiovasc Surg. 2016 Dec; 152(6):1616-1617. PMID: 27566890.
      View in: PubMed
    21. Kleiman NS. Are Immature Platelets Growing Up?: Toward a New Marker of Antiplatelet Drug Resistance. J Am Coll Cardiol. 2016 Jul 19; 68(3):294-6. PMID: 27417008.
      View in: PubMed
    22. Ibrahim H, Nadipalli S, Usmani S, DeLao T, Green L, Kleiman NS. Detection and quantification of circulating immature platelets: agreement between flow cytometric and automated detection. J Thromb Thrombolysis. 2016 Jul; 42(1):77-83. PMID: 26831482.
      View in: PubMed
    23. Kleiman NS. VWF, ADAMTS13, and acute coronary syndromes. Blood. 2016 Jun 9; 127(23):2788-9. PMID: 27282945.
      View in: PubMed
    24. Skelding KA, Yakubov SJ, Kleiman NS, Reardon MJ, Adams DH, Huang J, Forrest JK, Popma JJ. Transcatheter Aortic Valve Replacement Versus Surgery in Women at High Risk for Surgical Aortic Valve Replacement (from the CoreValve US High Risk Pivotal Trial). Am J Cardiol. 2016 Aug 15; 118(4):560-6. PMID: 27381665.
      View in: PubMed
    25. Deeb GM, Reardon MJ, Chetcuti S, Patel HJ, Grossman PM, Yakubov SJ, Kleiman NS, Coselli JS, Gleason TG, Lee JS, Hermiller JB, Heiser J, Merhi W, Zorn GL, Tadros P, Robinson N, Petrossian G, Hughes GC, Harrison JK, Maini B, Mumtaz M, Conte J, Resar J, Aharonian V, Pfeffer T, Oh JK, Qiao H, Adams DH, Popma JJ. 3-Year Outcomes in High-Risk Patients Who Underwent Surgical or Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. 2016 Jun 7; 67(22):2565-74. PMID: 27050187.
      View in: PubMed
    26. Reardon MJ, Kleiman NS. How Many Roads Lead to Rome? JACC Cardiovasc Interv. 2016 Mar 14; 9(5):481-3. PMID: 26965938.
      View in: PubMed
    27. Gleason TG, Schindler JT, Adams DH, Reardon MJ, Kleiman NS, Caplan LR, Conte JV, Deeb GM, Hughes GC, Chenoweth S, Popma JJ. The risk and extent of neurologic events are equivalent for high-risk patients treated with transcatheter or surgical aortic valve replacement. J Thorac Cardiovasc Surg. 2016 Jul; 152(1):85-96. PMID: 27085389.
      View in: PubMed
    28. Ramlawi B, Abu Saleh WK, Al Jabbari O, Barker CM, Kleiman NS, Reardon MJ. Minimally Invasive Repair of Left Ventricular Pseudoaneurysm after Transapical Transcatheter Aortic Valve Replacement. Tex Heart Inst J. 2016 Feb; 43(1):75-7. PMID: 27047291; PMCID: PMC4810592.
    29. Kleiman NS. What Happens in the Cath Lab Stays in the Cath Lab, or Does It?: Intraprocedural Thrombotic Events in Patients With Acute Coronary Syndromes. JACC Cardiovasc Interv. 2016 Feb 22; 9(4):338-40. PMID: 26803419.
      View in: PubMed
    30. Kleiman NS, Reardon MJ. Advances in Transcatheter Aortic Valve Replacement. Methodist Debakey Cardiovasc J. 2016 Jan-Mar; 12(1):33-6. PMID: 27127560; PMCID: PMC4847966.
    31. Reardon MJ, Kleiman NS. Watching a Procedure Evolve: Sequential Findings From the TVT Registry. Ann Thorac Surg. 2016 Feb; 101(2):417-8. PMID: 26652135.
      View in: PubMed
    32. Reardon MJ, Kleiman NS. Watching a Procedure Evolve: Sequential Findings From the TVT Registry. J Am Coll Cardiol. 2015 Dec 29; 66(25):2824-6. PMID: 26652231.
      View in: PubMed
    33. Abu Saleh WK, Tang GH, Ahmad H, Cohen M, Undemir C, Lansman SL, Reyes M, Barker CM, Kleiman NS, Reardon MJ, Ramlawi B. Vascular complication can be minimized with a balloon-expandable, re-collapsible sheath in TAVR with a self-expanding bioprosthesis. Catheter Cardiovasc Interv. 2016 Jul; 88(1):135-43. PMID: 26603266.
      View in: PubMed
    34. Zorn GL, Little SH, Tadros P, Deeb GM, Gleason TG, Heiser J, Kleiman NS, Oh JK, Popma JJ, Adams D, Huang J, Reardon MJ. Prosthesis-patient mismatch in high-risk patients with severe aortic stenosis: A randomized trial of a self-expanding prosthesis. J Thorac Cardiovasc Surg. 2016 Apr; 151(4):1014-1023.e3. PMID: 26614412.
      View in: PubMed
    35. Oh JK, Little SH, Abdelmoneim SS, Reardon MJ, Kleiman NS, Lin G, Bach D, Gillam L, Kar B, Coselli J, Sengupta PP, Grewal K, Chang J, Chang Y, Boulware M, Adams DH, Popma JJ. Regression of Paravalvular Aortic Regurgitation and Remodeling of Self-Expanding Transcatheter Aortic Valve: An Observation From the CoreValve U.S. Pivotal Trial. JACC Cardiovasc Imaging. 2015 Dec; 8(12):1364-75. PMID: 26508386.
      View in: PubMed
    36. Abu Saleh WK, Goswami R, Jabbari OA, Barker C, Kleiman NS, Reardon MJ, Ramlawi B. Transcatheter Treatment of Apicoaortic Conduit Dysfunction. J Card Surg. 2015 Dec; 30(12):885-7. PMID: 26440901.
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    37. Yakubov SJ, Adams DH, Watson DR, Reardon MJ, Kleiman NS, Heimansohn D, Hermiller J, Hughes GC, Harrison JK, Coselli J, Diez J, Schreiber T, Gleason TG, Conte J, Deeb GM, Huang J, Oh J, Byrne T, Caskey M, Popma JJ. 2-Year Outcomes After Iliofemoral Self-Expanding Transcatheter Aortic Valve Replacement in Patients With Severe Aortic Stenosis Deemed Extreme Risk for Surgery. J Am Coll Cardiol. 2015 Sep 22; 66(12):1327-34. PMID: 26383718.
      View in: PubMed
    38. Reardon MJ, Kleiman NS. At 5?years, transcatheter aortic valve replacement had similar rates of mortality and stroke as surgical aortic valve replacement in high-risk patients. Evid Based Med. 2015 Dec; 20(6):212-3. PMID: 26296815.
      View in: PubMed
    39. Chaikriangkrai K, Goswami R, Little S, Chang SM, Ramlawi B, Jhun HY, Kleiman N, Reardon MJ, Barker C. Bioprosthetic Mitral Transcatheter Transapical Valve-in-Valve Implantation for Mitral Stenosis in an End-Stage Renal Disease Patient. J Card Surg. 2015 Sep; 30(9):697-700. PMID: 26228701.
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    40. Abu Saleh WK, Goswami R, Chinnadurai P, Al Jabbari O, Barker CM, Lin CH, Kleiman N, Reardon MJ, Ramlawi B. Direct Aortic Access Transcatheter Aortic Valve Replacement: Three-Dimensional Computed Tomography Planning and Real-Time Fluoroscopic Image Guidance. J Heart Valve Dis. 2015 Jul; 24(4):420-5. PMID: 26897809.
      View in: PubMed
    41. Ramlawi B, Abu Saleh WK, Jabbari OA, Barker C, Lin C, Reyes M, Kleiman NS, Reardon MT. Short-Term Outcomes with Direct Aortic Access for Transcatheter Aortic Valve Replacement. J Heart Valve Dis. 2015 Jul; 24(4):426-32. PMID: 26897810.
      View in: PubMed
    42. Kleiman NS, Kolandaivelu K. Expanding the Roster: Developing New Inhibitors of Intravascular Thrombosis. J Am Coll Cardiol. 2015 Jun 9; 65(22):2416-9. PMID: 26046735.
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    43. Reardon MJ, Adams DH, Kleiman NS, Yakubov SJ, Coselli JS, Deeb GM, Gleason TG, Lee JS, Hermiller JB, Chetcuti S, Heiser J, Merhi W, Zorn GL, Tadros P, Robinson N, Petrossian G, Hughes GC, Harrison JK, Maini B, Mumtaz M, Conte JV, Resar JR, Aharonian V, Pfeffer T, Oh JK, Qiao H, Popma JJ. 2-Year Outcomes in Patients Undergoing Surgical or Self-Expanding Transcatheter Aortic Valve Replacement. J Am Coll Cardiol. 2015 Jul 14; 66(2):113-21. PMID: 26055947.
      View in: PubMed
    44. Kleiman NS. Is it time to join the cult? Radial access and percutaneous coronary intervention. Circ Cardiovasc Interv. 2015 Jun; 8(6):e002745. PMID: 26056250.
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    45. Ibrahim H, Barker CM, Reardon MJ, Kleiman NS. Suicide left ventricle due to conduction disturbance following transcatheter aortic valve replacement and reversal with restoration of sinus rhythm: is there life after death? J Invasive Cardiol. 2015 Jun; 27(6):E107-9. PMID: 26028658.
      View in: PubMed
    46. Goswami R, Colin B, Jackson M, Kleiman N, Little S. Transesophageal echocardiography-guided percutaneous intervention for a mitral valve leaflet perforation. JACC Cardiovasc Interv. 2015 Apr 27; 8(5):754-5. PMID: 25946451.
      View in: PubMed
    47. Osnabrugge RL, Arnold SV, Reynolds MR, Magnuson EA, Wang K, Gaudiani VA, Stoler RC, Burdon TA, Kleiman N, Reardon MJ, Adams DH, Popma JJ, Cohen DJ. Health status after transcatheter aortic valve replacement in patients at extreme surgical risk: results from the CoreValve U.S. trial. JACC Cardiovasc Interv. 2015 Feb; 8(2):315-23. PMID: 25700755; PMCID: PMC4362674.
    48. Ibrahim H, Schutt RC, Hannawi B, DeLao T, Barker CM, Kleiman NS. Association of immature platelets with adverse cardiovascular outcomes. J Am Coll Cardiol. 2014 Nov 18-25; 64(20):2122-9. PMID: 25457402.
      View in: PubMed
    49. Reardon MJ, Adams DH, Coselli JS, Deeb GM, Kleiman NS, Chetcuti S, Yakubov SJ, Heimansohn D, Hermiller J, Hughes GC, Harrison JK, Khabbaz K, Tadros P, Zorn GL, Merhi W, Heiser J, Petrossian G, Robinson N, Maini B, Mumtaz M, Lee JS, Gleason TG, Resar J, Conte J, Watson D, Chenoweth S, Popma JJ. Self-expanding transcatheter aortic valve replacement using alternative access sites in symptomatic patients with severe aortic stenosis deemed extreme risk of surgery. J Thorac Cardiovasc Surg. 2014 Dec; 148(6):2869-76.e1-7. PMID: 25152474.
      View in: PubMed
    50. Kassi M, Lopez J, Barker C, Trerotola S, Kleiman N, Kurrelmeyer K. Case report: It wasn't cupid: multimodality imaging of inferior vena cava filter fracture with strut migration to the interventricular septum. Methodist Debakey Cardiovasc J. 2014 Jul-Sep; 10(3):198-200. PMID: 25574350; PMCID: PMC4280247.
    51. Pershad A, Fraij G, Massaro JM, David SW, Kleiman NS, Denktas AE, Wilson BH, Dixon SR, Ohman EM, Douglas PS, Moses JW, O'Neill WW. Comparison of the use of hemodynamic support in patients ?80 years versus patients <80 years during high-risk percutaneous coronary interventions (from the Multicenter PROTECT II Randomized Study). Am J Cardiol. 2014 Sep 1; 114(5):657-64. PMID: 25037676.
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    52. Lincoff AM, Roe M, Aylward P, Galla J, Rynkiewicz A, Guetta V, Zelizko M, Kleiman N, White H, McErlean E, Erlinge D, Laine M, Dos Santos Ferreira JM, Goodman S, Mehta S, Atar D, Suryapranata H, Jensen SE, Forster T, Fernandez-Ortiz A, Schoors D, Radke P, Belli G, Brennan D, Bell G, Krucoff M. Inhibition of delta-protein kinase C by delcasertib as an adjunct to primary percutaneous coronary intervention for acute anterior ST-segment elevation myocardial infarction: results of the PROTECTION AMI Randomized Controlled Trial. Eur Heart J. 2014 Oct 1; 35(37):2516-23. PMID: 24796339.
      View in: PubMed
    53. Bangalore S, Pencina MJ, Kleiman NS, Cohen DJ. Heparin monotherapy or bivalirudin during percutaneous coronary intervention in patients with non-ST-segment-elevation acute coronary syndromes or stable ischemic heart disease: results from the Evaluation of Drug-Eluting Stents and Ischemic Events registry. Circ Cardiovasc Interv. 2014 Jun; 7(3):365-73. PMID: 24736878.
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    54. Adams DH, Popma JJ, Reardon MJ, Yakubov SJ, Coselli JS, Deeb GM, Gleason TG, Buchbinder M, Hermiller J, Kleiman NS, Chetcuti S, Heiser J, Merhi W, Zorn G, Tadros P, Robinson N, Petrossian G, Hughes GC, Harrison JK, Conte J, Maini B, Mumtaz M, Chenoweth S, Oh JK. Transcatheter aortic-valve replacement with a self-expanding prosthesis. N Engl J Med. 2014 May 8; 370(19):1790-8. PMID: 24678937.
      View in: PubMed
    55. Popma JJ, Adams DH, Reardon MJ, Yakubov SJ, Kleiman NS, Heimansohn D, Hermiller J, Hughes GC, Harrison JK, Coselli J, Diez J, Kafi A, Schreiber T, Gleason TG, Conte J, Buchbinder M, Deeb GM, Carabello B, Serruys PW, Chenoweth S, Oh JK. Transcatheter aortic valve replacement using a self-expanding bioprosthesis in patients with severe aortic stenosis at extreme risk for surgery. J Am Coll Cardiol. 2014 May 20; 63(19):1972-81. PMID: 24657695.
      View in: PubMed
    56. Kleiman NS. Are we there yet? deciding when it is safe (and wise) to stop clopidogrel after stent implantation. J Interv Cardiol. 2014 Apr; 27(2):127-30. PMID: 24617441.
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    57. Ramlawi B, Bedeir K, Barker C, Lin CH, Kleiman N, Reardon M. Direct aortic and subclavian access for transcatheter aortic valve replacement: decision making and technique. J Thorac Cardiovasc Surg. 2014 Jul; 148(1):353-6. PMID: 24655905.
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    58. Kuster DW, Cardenas-Ospina A, Miller L, Liebetrau C, Troidl C, Nef HM, Möllmann H, Hamm CW, Pieper KS, Mahaffey KW, Kleiman NS, Stuyvers BD, Marian AJ, Sadayappan S. Release kinetics of circulating cardiac myosin binding protein-C following cardiac injury. Am J Physiol Heart Circ Physiol. 2014 Feb 15; 306(4):H547-56. PMID: 24337456; PMCID: PMC3920245.
    59. Dasari TW, Cohen DJ, Kleiman NS, Keyes MJ, Yen CH, Hanna EB, Saucedo JF. Statin therapy in patients with chronic kidney disease undergoing percutaneous coronary intervention (from the Evaluation of Drug Eluting Stents and Ischemic Events Registry). Am J Cardiol. 2014 Feb 15; 113(4):621-5. PMID: 24342762.
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    60. Cohen MG, Ghatak A, Kleiman NS, Naidu SS, Massaro JM, Kirtane AJ, Moses J, Magnus Ohman E, Džavík V, Palacios IF, Heldman AW, Popma JJ, O'Neill WW. Optimizing rotational atherectomy in high-risk percutaneous coronary interventions: insights from the PROTECT ?? study. Catheter Cardiovasc Interv. 2014 Jun 1; 83(7):1057-64. PMID: 24174321.
      View in: PubMed
    61. Bangalore S, Pencina MJ, Kleiman NS, Cohen DJ. Prognostic implications of procedural vs spontaneous myocardial infarction: results from the Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry. Am Heart J. 2013 Dec; 166(6):1027-34. PMID: 24268217.
      View in: PubMed
    62. Estep JD, Cordero-Reyes AM, Bhimaraj A, Trachtenberg B, Khalil N, Loebe M, Bruckner B, Orrego CM, Bismuth J, Kleiman NS, Torre-Amione G. Percutaneous placement of an intra-aortic balloon pump in the left axillary/subclavian position provides safe, ambulatory long-term support as bridge to heart transplantation. JACC Heart Fail. 2013 Oct; 1(5):382-8. PMID: 24621970.
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    63. Braun OÖ, Angiolillo DJ, Ferreiro JL, Jakubowski JA, Winters KJ, Effron MB, Duvvuru S, Costigan TM, Sundseth S, Walker JR, Saucedo JF, Kleiman NS, Varenhorst C. Enhanced active metabolite generation and platelet inhibition with prasugrel compared to clopidogrel regardless of genotype in thienopyridine metabolic pathways. Thromb Haemost. 2013 Dec; 110(6):1223-31. PMID: 24009042.
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    64. Chaikriangkrai K, Polsani V, Wei L, Kleiman N, Chang SM. Stenting of a left main coronary artery compressed by a dilated main pulmonary artery. Catheter Cardiovasc Interv. 2013 Nov 1; 82(5):E684-7. PMID: 23804497.
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    65. Vavalle JP, Clare R, Chiswell K, Rao SV, Petersen JL, Kleiman NS, Mahaffey KW, Wang TY. Prognostic significance of bleeding location and severity among patients with acute coronary syndromes. JACC Cardiovasc Interv. 2013 Jul; 6(7):709-17. PMID: 23866183; PMCID: PMC3884698.
    66. Alam M, Virani SS, Shahzad SA, Siddiqui S, Siddiqui KH, Mumtaz SA, Kleiman NS, Coselli JS, Lakkis NM, Jneid H. Comparison by meta-analysis of percutaneous coronary intervention versus coronary artery bypass grafting in patients with a mean age of ?70 years. Am J Cardiol. 2013 Sep 1; 112(5):615-22. PMID: 23726179.
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    67. Gordon PC, Cohen DJ, Kleiman NS, Montgomery JA, Semder CA, Kennedy KF, Keyes MJ, Piana RN. In-hospital and one year outcomes with drug-eluting versus bare metal stents in large native coronary arteries: a report from the Evaluation of Drug-Eluting Stents and Ischemic Events registry. Catheter Cardiovasc Interv. 2013 Oct 1; 82(4):E356-64. PMID: 22511502.
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    68. Fatemi O, Torguson R, Chen F, Ahmad S, Badr S, Satler LF, Pichard AD, Kleiman NS, Waksman R. Red cell distribution width as a bleeding predictor after percutaneous coronary intervention. Am Heart J. 2013 Jul; 166(1):104-9. PMID: 23816028.
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    69. Alam M, Bandeali SJ, Kayani WT, Ahmad W, Shahzad SA, Jneid H, Birnbaum Y, Kleiman NS, Coselli JS, Ballantyne CM, Lakkis N, Virani SS. Comparison by meta-analysis of mortality after isolated coronary artery bypass grafting in women versus men. Am J Cardiol. 2013 Aug 1; 112(3):309-17. PMID: 23642381.
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    70. Lopes RD, White JA, Atar D, Keltai M, Kleiman NS, White HD, Widimsky P, Zeymer U, Giugliano RP, Tricoci P, Braunwald E, Bode C, Ohman EM, Armstrong PW, Newby LK. Incidence, treatment, and outcomes of atrial fibrillation complicating non-ST-segment elevation acute coronary syndromes. Int J Cardiol. 2013 Oct 3; 168(3):2510-7. PMID: 23578889.
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    71. Fatemi O, Paranilam J, Rainow A, Kennedy K, Choi J, Cutlip D, Pencina M, Berger PB, Cohen DJ, Kleiman NS. Red cell distribution width is a predictor of mortality in patients undergoing percutaneous coronary intervention. J Thromb Thrombolysis. 2013 Jan; 35(1):57-64. PMID: 22752404.
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    72. Alam M, Huang HD, Shahzad SA, Kar B, Virani SS, Rogers PA, Paniagua D, Bozkurt B, Palacios I, Kleiman NS, Jneid H. Percutaneous coronary intervention vs. coronary artery bypass graft surgery for unprotected left main coronary artery disease in the drug-eluting stents era--an aggregate data meta-analysis of 11,148 patients. Circ J. 2013; 77(2):372-82. PMID: 23123552.
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    73. Stolker JM, Cohen DJ, Kennedy KF, Pencina MJ, Lindsey JB, Mauri L, Cutlip DE, Kleiman NS. Repeat revascularization after contemporary percutaneous coronary intervention: an evaluation of staged, target lesion, and other unplanned revascularization procedures during the first year. Circ Cardiovasc Interv. 2012 Dec; 5(6):772-82. PMID: 23093553.
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    74. O'Neill WW, Kleiman NS, Moses J, Henriques JP, Dixon S, Massaro J, Palacios I, Maini B, Mulukutla S, Dzavík V, Popma J, Douglas PS, Ohman M. A prospective, randomized clinical trial of hemodynamic support with Impella 2.5 versus intra-aortic balloon pump in patients undergoing high-risk percutaneous coronary intervention: the PROTECT II study. Circulation. 2012 Oct 2; 126(14):1717-27. PMID: 22935569.
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    75. Alviar CL, Tellez A, Wang M, Potts P, Smith D, Tsui M, Budzynski W, Raizner AE, Kleiman NS, Lev EI, Granada JF, Kaluza GL. Low-dose sirolimus-eluting hydroxyapatite coating on stents does not increase platelet activation and adhesion ex vivo. J Thromb Thrombolysis. 2012 Jul; 34(1):91-8. PMID: 22350685.
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    76. Caputo RP, Goel A, Pencina M, Cohen DJ, Kleiman NS, Yen CH, Waksman R, Tolerico P, Dhar G, Gordon P, Bach RG, Lopez JJ. Impact of drug eluting stent length on outcomes of percutaneous coronary intervention (from the EVENT registry). Am J Cardiol. 2012 Aug 1; 110(3):350-5. PMID: 22560770.
      View in: PubMed
    77. Tolerico PH, Cohen DJ, Kleiman NS, Berger PB, Brilakis ES, Piana RN, Shammo S, Keyes MJ, Kennedy KF, Massaro JM, Saucedo JF. In-hospital and 1-year outcomes with drug-eluting versus bare metal stents in saphenous vein graft intervention: a report from the EVENT registry. Catheter Cardiovasc Interv. 2012 Dec 1; 80(7):1127-36. PMID: 22431166.
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    78. Maini B, Naidu SS, Mulukutla S, Kleiman N, Schreiber T, Wohns D, Dixon S, Rihal C, Dave R, O'Neill W. Real-world use of the Impella 2.5 circulatory support system in complex high-risk percutaneous coronary intervention: the USpella Registry. Catheter Cardiovasc Interv. 2012 Nov 1; 80(5):717-25. PMID: 22105829.
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    79. Alam M, Bandeali SJ, Virani SS, Jneid HM, Shahzad SA, Ramanathan KB, Kar B, Kleiman NS, Lakkis N. Clinical outcomes of percutaneous interventions in saphenous vein grafts using drug-eluting stents compared to bare-metal stents: a comprehensive meta-analysisof all randomized clinical trials. Clin Cardiol. 2012 May; 35(5):291-6. PMID: 22488047.
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    82. Kleiman NS. Grabbing the horns of a dilemma: the duration of dual antiplatelet therapy after stent implantation. Circulation. 2012 Apr 24; 125(16):1967-70. PMID: 22438531.
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    83. Novack V, Pencina M, Cohen DJ, Kleiman NS, Yen CH, Saucedo JF, Berger PB, Cutlip DE. Troponin criteria for myocardial infarction after percutaneous coronary intervention. Arch Intern Med. 2012 Mar 26; 172(6):502-8. PMID: 22371874.
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    84. Win HK, Polsani V, Chang SM, Kleiman NS. Stent-assisted coil embolization of a large fusiform aneurysm of proximal anterior descending artery: novel treatment for coronary aneurysms. Circ Cardiovasc Interv. 2012 Feb 1; 5(1):e3-5. PMID: 22338006.
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    85. Ibrahim H, Nadipalli S, DeLao T, Guthikonda S, Kleiman NS. Immature platelet fraction (IPF) determined with an automated method predicts clopidogrel hyporesponsiveness. J Thromb Thrombolysis. 2012 Feb; 33(2):137-42. PMID: 22198802.
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    86. Stolker JM, Cohen DJ, Lindsey JB, Kennedy KF, Kleiman NS, Marso SP. Mode of death after contemporary percutaneous coronary intervention: a report from the Evaluation of Drug Eluting Stents and Ischemic Events registry. Am Heart J. 2011 Nov; 162(5):914-21. PMID: 22093209.
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    87. Venkitachalam L, Lei Y, Magnuson EA, Chan PS, Stolker JM, Kennedy KF, Kleiman NS, Cohen DJ. Survival benefit with drug-eluting stents in observational studies: fact or artifact? Circ Cardiovasc Qual Outcomes. 2011 Nov 1; 4(6):587-94. PMID: 21988921.
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    88. Buergler JM, Kleiman NS. Balancing hemostasis and thrombosis in interventional vascular medicine and surgery. Methodist Debakey Cardiovasc J. 2011 Oct-Dec; 7(4):19-23. PMID: 22143472.
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    89. Lindsey JB, Kennedy KF, Stolker JM, Gilchrist IC, Mukherjee D, Marso SP, Pencina MJ, Kleiman NS, Cohen DJ. Prognostic implications of creatine kinase-MB elevation after percutaneous coronary intervention: results from the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) registry. Circ Cardiovasc Interv. 2011 Oct 1; 4(5):474-80. PMID: 21972402.
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    90. Bangalore S, Cohen DJ, Kleiman NS, Regev-Beinart T, Rao SV, Pencina MJ, Mauri L. Bleeding risk comparing targeted low-dose heparin with bivalirudin in patients undergoing percutaneous coronary intervention: results from a propensity score-matched analysis of the Evaluation of Drug-Eluting Stents and Ischemic Events (EVENT) registry. Circ Cardiovasc Interv. 2011 Oct 1; 4(5):463-73. PMID: 21972401.
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    91. Kleiman NS. Bringing it all together: integration of physiology with anatomy during cardiac catheterization. J Am Coll Cardiol. 2011 Sep 13; 58(12):1219-21. PMID: 21903053.
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    92. Venkitachalam L, Lei Y, Stolker JM, Mahoney EM, Amin AP, Lindsey JB, Kennedy KF, Pencina MJ, Lopez JJ, Kleiman NS, Cohen DJ. Clinical and economic outcomes of liberal versus selective drug-eluting stent use: insights from temporal analysis of the multicenter Evaluation of Drug Eluting Stents and Ischemic Events (EVENT) registry. Circulation. 2011 Aug 30; 124(9):1028-37. PMID: 21844081.
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    93. French JK, Armstrong PW, Cohen E, Kleiman NS, O'Connor CM, Hellkamp AS, Stebbins A, Holmes DR, Hochman JS, Granger CB, Mahaffey KW. Cardiogenic shock and heart failure post-percutaneous coronary intervention in ST-elevation myocardial infarction: observations from "Assessment of Pexelizumab in Acute Myocardial Infarction". Am Heart J. 2011 Jul; 162(1):89-97. PMID: 21742094.
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    94. Amin AP, Kennedy KF, Pencina M, Berger P, Piana RN, Lopez J, Kleiman N, Cohen DJ. Effect of clopidogrel pretreatment on ischemic complications of percutaneous coronary intervention among bivalirudin-treated patients (from the EVENT registry). Am J Cardiol. 2011 Jun 15; 107(12):1751-6. PMID: 21640216.
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    95. Rodriguez G, Starr AZ, Czernuszewicz GZ, Manhas A, Alhariri A, Willerson JT, Reist CJ, Pieper K, Mahaffey KW, Marian AJ, Kleiman NS. Determinants of plasma vitamin D levels in patients with acute coronary syndromes. Eur J Clin Invest. 2011 Dec; 41(12):1299-309. PMID: 21615392.
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    96. Mahaffey KW, Pieper KS, Lokhnygina Y, Califf RM, Antman EM, Kleiman NS, Goodman SG, White HD, Rao SV, Hochman JS, Cohen M, Col JJ, Roe MT, Ferguson JJ. The impact of postrandomization crossover of therapy in acute coronary syndromes care. Circ Cardiovasc Qual Outcomes. 2011 Mar; 4(2):211-9. PMID: 21304094.
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    97. Becker RC, Mahaffey KW, Yang H, Marian AJ, Furman MI, Michael Lincoff A, Hazen SL, Petersen JL, Reist CJ, Kleiman NS. Heparin-associated anti-Xa activity and platelet-derived prothrombotic and proinflammatory biomarkers in moderate to high-risk patients with acute coronary syndrome. J Thromb Thrombolysis. 2011 Feb; 31(2):146-53. PMID: 21086021.
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    98. Brilakis ES, Cohen DJ, Kleiman NS, Pencina M, Nassif D, Saucedo J, Piana RN, Banerjee S, Keyes MJ, Yen CH, Berger PB. Incidence and clinical outcome of minor surgery in the year after drug-eluting stent implantation: results from the Evaluation of Drug-Eluting Stents and Ischemic Events Registry. Am Heart J. 2011 Feb; 161(2):360-6. PMID: 21315220.
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    99. Mahaffey KW, Wampole JL, Stebbins A, Berdan LG, McAfee D, Rorick TL, French JK, Kleiman NS, O'Connor CM, Cohen EA, Granger CB, Armstrong PW. Strategic lessons from the clinical event classification process for the Assessment of Pexelizumab in Acute Myocardial Infarction (APEX-AMI) trial. Contemp Clin Trials. 2011 Mar; 32(2):178-87. PMID: 21220052.
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    100. Kleiman N, Reardon MJ. TAVI: transcatheter aortic valve implantation. Methodist Debakey Cardiovasc J. 2011 Jan-Mar; 7(1):49-52. PMID: 21490555.
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    101. Giugliano RP, Pollack CV, Brogan GX, Cohen M, Diercks DB, Grines CL, Henry TD, Kleiman NS. Acute coronary syndromes: from the emergency department to the catheterization laboratory-integrating evidence from recent ACS/NSTEMI trials into clinical practice: an evidence-based review of recent clinical trial results and report on a roundtable discussion. J Interv Cardiol. 2011 Apr; 24(2):119-36. PMID: 21114529.
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    102. Mangalpally KK, Kleiman NS. The safety of clopidogrel. Expert Opin Drug Saf. 2011 Jan; 10(1):85-95. PMID: 21091040.
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    103. Pollack CV, Brogan GX, Cohen M, Diercks D, Grines C, Henry TD, Kleiman NS, Giugliano RP. ED to catheterization laboratory: a roundtable integrating trials with practice. Am J Emerg Med. 2011 Nov; 29(9):1203-16. PMID: 20971595.
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    104. Mangalpally KK, Siqueiros-Garcia A, Vaduganathan M, Dong JF, Kleiman NS, Guthikonda S. Platelet activation patterns in platelet size sub-populations: differential responses to aspirin in vitro. J Thromb Thrombolysis. 2010 Oct; 30(3):251-62. PMID: 20502945.
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    105. Lopez JJ, Keyes MJ, Nathan S, Piana R, Pencina M, Dhar G, Marso S, Rao S, Shammo S, Marquardt W, Cohen DJ, Kleiman NS. Rapid adoption of drug-eluting stents: clinical practices and outcomes from the early drug-eluting stent era. Am Heart J. 2010 Oct; 160(4):767-74. PMID: 20934573.
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    106. Berger PB, Kleiman NS, Pencina MJ, Hsieh WH, Steinhubl SR, Jeremias A, Sonel A, Browne K, Barseness G, Cohen DJ. Frequency of major noncardiac surgery and subsequent adverse events in the year after drug-eluting stent placement results from the EVENT (Evaluation of Drug-Eluting Stents and Ischemic Events) Registry. JACC Cardiovasc Interv. 2010 Sep; 3(9):920-7. PMID: 20850090.
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    107. Stolker JM, Kennedy KF, Lindsey JB, Marso SP, Pencina MJ, Cutlip DE, Mauri L, Kleiman NS, Cohen DJ. Predicting restenosis of drug-eluting stents placed in real-world clinical practice: derivation and validation of a risk model from the EVENT registry. Circ Cardiovasc Interv. 2010 Aug; 3(4):327-34. PMID: 20606136.
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    108. Kleiman NS. PLATO study of ticagrelor versus clopidogrel in patients with high-risk acute coronary syndromes. Curr Cardiol Rep. 2010 Jul; 12(4):283-5. PMID: 20432073.
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    109. Cohen M, Levine GN, Pieper KS, Lan L, Antman EM, Aylward PE, White HD, Kleiman NS, Califf RM, Mahaffey KW. Enoxaparin 0.3 mg/kg IV supplement for patients transitioning to PCI after subcutaneous enoxaparin therapy for NSTE ACS: a subgroup analysis from the SYNERGY trial. Catheter Cardiovasc Interv. 2010 May 1; 75(6):928-35. PMID: 20432399.
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    110. Kleiman NS. Resistance or resistors? Has Ohm's law come to antiplatelet therapy? Am Heart J. 2010 May; 159(5):713-5. PMID: 20435177.
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    111. Rao SV, Melloni C, Myles-Dimauro S, Broderick S, Kosinski AS, Kleiman NS, Dzavík V, Tanguay JF, Chandna H, Gammon R, Rivera E, Alexander JH, Fier I, Roach J, Becker RC. Evaluation of a new heparin agent in percutaneous coronary intervention: results of the phase 2 evaluation of M118 IN pErcutaNeous Coronary intErvention (EMINENCE) Trial. Circulation. 2010 Apr 20; 121(15):1713-21. PMID: 20368520.
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    112. Lev EI, Solodky A, Harel N, Mager A, Brosh D, Assali A, Roller M, Battler A, Kleiman NS, Kornowski R. Treatment of aspirin-resistant patients with omega-3 fatty acids versus aspirin dose escalation. J Am Coll Cardiol. 2010 Jan 12; 55(2):114-21. PMID: 20117379.
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    113. Granada JF, Alviar CL, Wallace-Bradley D, Osteen M, Dave B, Tellez A, Win HK, Kleiman NS, Kaluza GL, Lev EI. Patterns of activation and deposition of platelets exposed to the polymeric surface of the paclitaxel eluting stent. J Thromb Thrombolysis. 2010 Jan; 29(1):60-9. PMID: 19466381.
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    114. Bhatt DL, Lincoff AM, Gibson CM, Stone GW, McNulty S, Montalescot G, Kleiman NS, Goodman SG, White HD, Mahaffey KW, Pollack CV, Manoukian SV, Widimsky P, Chew DP, Cura F, Manukov I, Tousek F, Jafar MZ, Arneja J, Skerjanec S, Harrington RA. Intravenous platelet blockade with cangrelor during PCI. N Engl J Med. 2009 Dec 10; 361(24):2330-41. PMID: 19915222.
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    115. Harrington RA, Stone GW, McNulty S, White HD, Lincoff AM, Gibson CM, Pollack CV, Montalescot G, Mahaffey KW, Kleiman NS, Goodman SG, Amine M, Angiolillo DJ, Becker RC, Chew DP, French WJ, Leisch F, Parikh KH, Skerjanec S, Bhatt DL. Platelet inhibition with cangrelor in patients undergoing PCI. N Engl J Med. 2009 Dec 10; 361(24):2318-29. PMID: 19915221.
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    116. Putney DR, Kleiman NS, Fromm RE, Buergler JM. Impact of computerized dosing on eptifibatide-associated bleeding and mortality. Am Heart J. 2009 Dec; 158(6):1018-23. PMID: 19958870.
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    117. Lindsey JB, Marso SP, Pencina M, Stolker JM, Kennedy KF, Rihal C, Barsness G, Piana RN, Goldberg SL, Cutlip DE, Kleiman NS, Cohen DJ. Prognostic impact of periprocedural bleeding and myocardial infarction after percutaneous coronary intervention in unselected patients: results from the EVENT (evaluation of drug-eluting stents and ischemic events) registry. JACC Cardiovasc Interv. 2009 Nov; 2(11):1074-82. PMID: 19926047.
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    118. Novack V, Cutlip D, Kleiman N, Pencina M, Mauri L, Yen CH, Berger P, Goldberg S, Kellett M, Waksman R, Hong M, Raizner AE, Cohen DJ. In-hospital and 1-year outcomes among unselected percutaneous coronary intervention patients treated with either sirolimus- or paclitaxel-eluting stents: results from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry. JACC Cardiovasc Interv. 2009 Aug; 2(8):767-75. PMID: 19695546.
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    119. Holmes DR, Kereiakes DJ, Kleiman NS, Moliterno DJ, Patti G, Grines CL. Combining antiplatelet and anticoagulant therapies. J Am Coll Cardiol. 2009 Jul 7; 54(2):95-109. PMID: 19573725.
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    120. Novack V, Tsyvine D, Cohen DJ, Pencina M, Dubin J, Dehghani H, Kleiman NS, Cutlip DE. Multivessel drug-eluting stenting and impact of diabetes mellitus--a report from the EVENT registry. Catheter Cardiovasc Interv. 2009 Jun 1; 73(7):874-80. PMID: 19180665.
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    121. Ben-Dor I, Kleiman NS, Lev E. Assessment, mechanisms, and clinical implication of variability in platelet response to aspirin and clopidogrel therapy. Am J Cardiol. 2009 Jul 15; 104(2):227-33. PMID: 19576352.
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    122. Little SH, Kleiman N, Guthikonda S. Percutaneous paravalvular repair: guidance using live 3-dimensional transesophageal echocardiography. J Am Coll Cardiol. 2009 Apr 21; 53(16):1467. PMID: 19371832.
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    123. Bhatt DL, Peterson ED, Harrington RA, Ou FS, Cannon CP, Gibson CM, Kleiman NS, Brindis RG, Peacock WF, Brener SJ, Menon V, Smith SC, Pollack CV, Gibler WB, Ohman EM, Roe MT. Prior polyvascular disease: risk factor for adverse ischaemic outcomes in acute coronary syndromes. Eur Heart J. 2009 May; 30(10):1195-202. PMID: 19339264.
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    124. Crespo EM, Oliveira GB, Honeycutt EF, Becker RC, Berger PB, Moliterno DJ, Anstrom KJ, Abrams CS, Kleiman NS, Moll S, Rice L, Rodgers JE, Steinhubl SR, Tapson VF, Granger CB, Ohman EM. Evaluation and management of thrombocytopenia and suspected heparin-induced thrombocytopenia in hospitalized patients: The Complications After Thrombocytopenia Caused by Heparin (CATCH) registry. Am Heart J. 2009 Apr; 157(4):651-7. PMID: 19332191.
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    125. Loebe M, Zade Asfahani WH, Petrov GP, Kleiman NS, Torre-Amione G. Surgical considerations on the use of the percutaneous ventricular assist device TandemHeart in critical aortic valve stenosis. Thorac Cardiovasc Surg. 2009 Feb; 57(1):50-2. PMID: 19169999.
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    126. Latif F, Kleiman NS, Cohen DJ, Pencina MJ, Yen CH, Cutlip DE, Moliterno DJ, Nassif D, Lopez JJ, Saucedo JF. In-hospital and 1-year outcomes among percutaneous coronary intervention patients with chronic kidney disease in the era of drug-eluting stents: a report from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry. JACC Cardiovasc Interv. 2009 Jan; 2(1):37-45. PMID: 19463396.
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    127. Kleiman NS. Searching for the ceiling: new reflections on the disposition and metabolism of clopidogrel. JACC Cardiovasc Interv. 2008 Dec; 1(6):628-30. PMID: 19463376.
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    128. Kleiman NS. Clopidogrel and calcium-channel antagonists: another drug-drug interaction for the ever-wary clinician? J Am Coll Cardiol. 2008 Nov 4; 52(19):1564-6. PMID: 19007593.
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    129. Vaduganathan M, Alviar CL, Arikan ME, Tellez A, Guthikonda S, DeLao T, Granada JF, Kleiman NS, Ballantyne CM, Lev EI. Platelet reactivity and response to aspirin in subjects with the metabolic syndrome. Am Heart J. 2008 Nov; 156(5):1002.e1-1002.e7. PMID: 19061719.
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    130. Little SH, Zekry SB, Zoghbi WA, Kleiman NS, Guthikonda S. Three-dimensional transesophageal echocardiogram provides real-time guidance during percutaneous paravalvular mitral repair. Circ Heart Fail. 2008 Nov; 1(4):293-4. PMID: 19808306.
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    131. Koshy SK, Kleiman NS, George LK, Misra V, Hillegass WB, Brott BC. Vascular changes and black hole phenomenon after coronary brachytherapy: a pathologically distinct entity. J Invasive Cardiol. 2008 Oct; 20(10):560-2. PMID: 18830004.
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    132. Guthikonda S, Alviar CL, Vaduganathan M, Arikan M, Tellez A, DeLao T, Granada JF, Dong JF, Kleiman NS, Lev EI. Role of reticulated platelets and platelet size heterogeneity on platelet activity after dual antiplatelet therapy with aspirin and clopidogrel in patients with stable coronary artery disease. J Am Coll Cardiol. 2008 Aug 26; 52(9):743-9. PMID: 18718422.
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    133. Garg R, Tellez A, Alviar C, Granada J, Kleiman NS, Lev EI. The effect of percutaneous coronary intervention on inflammatory response and endothelial progenitor cell recruitment. Catheter Cardiovasc Interv. 2008 Aug 1; 72(2):205-9. PMID: 18651648.
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    134. Jeremias A, Kleiman NS, Nassif D, Hsieh WH, Pencina M, Maresh K, Parikh M, Cutlip DE, Waksman R, Goldberg S, Berger PB, Cohen DJ. Prevalence and prognostic significance of preprocedural cardiac troponin elevation among patients with stable coronary artery disease undergoing percutaneous coronary intervention: results from the evaluation of drug eluting stents and ischemic events registry. Circulation. 2008 Aug 5; 118(6):632-8. PMID: 18645057.
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    135. Guthikonda S, Mangalpally K, Vaduganathan M, Patel R, Delao T, Bergeron AL, Dong JF, Lev EI, Kleiman NS. Increased platelet sensitivity among individuals with aspirin resistance - platelet aggregation to submaximal concentration of arachidonic acid predicts response to antiplatelet therapy. Thromb Haemost. 2008 Jul; 100(1):83-9. PMID: 18612542.
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    136. Kleiman NS. Should Prasugrel or Clopidogrel Be Used in Patients with ACS? Curr Cardiol Rep. 2008 Jul; 10(4):301-2. PMID: 18611364.
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    137. Kleiman NS, Freedman JE, Tracy PB, Furie BC, Bray PF, Rao SV, Phillips DR, Storey RF, Rusconi CP, French PA, Steinhubl SR, Becker RC. Platelets: developmental biology, physiology, and translatable platforms for preclinical investigation and drug development. Platelets. 2008 Jun; 19(4):239-51. PMID: 18569859.
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    138. Chan MY, Cohen MG, Dyke CK, Myles SK, Aberle LG, Lin M, Walder J, Steinhubl SR, Gilchrist IC, Kleiman NS, Vorchheimer DA, Chronos N, Melloni C, Alexander JH, Harrington RA, Tonkens RM, Becker RC, Rusconi CP. Phase 1b randomized study of antidote-controlled modulation of factor IXa activity in patients with stable coronary artery disease. Circulation. 2008 Jun 3; 117(22):2865-74. PMID: 18506005.
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    139. Kleiman NS. Will measuring vasodilator-stimulated phosphoprotein phosphorylation help us optimize the loading dose of clopidogrel? J Am Coll Cardiol. 2008 Apr 8; 51(14):1412-4. PMID: 18387445.
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    140. Intracoronary KAI-9803 as an adjunct to primary percutaneous coronary intervention for acute ST-segment elevation myocardial infarction. Circulation. 2008 Feb 19; 117(7):886-96. PMID: 18250271.
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    141. Mahaffey KW, Yang Q, Pieper KS, Antman EM, White HD, Goodman SG, Cohen M, Kleiman NS, Langer A, Aylward PE, Col JJ, Reist C, Ferguson JJ, Califf RM. Prediction of one-year survival in high-risk patients with acute coronary syndromes: results from the SYNERGY trial. J Gen Intern Med. 2008 Mar; 23(3):310-6. PMID: 18196350; PMCID: PMC2359476.
    142. Oliveira GB, Crespo EM, Becker RC, Honeycutt EF, Abrams CS, Anstrom KJ, Berger PB, Davidson-Ray LD, Eisenstein EL, Kleiman NS, Moliterno DJ, Moll S, Rice L, Rodgers JE, Steinhubl SR, Tapson VF, Ohman EM, Granger CB. Incidence and prognostic significance of thrombocytopenia in patients treated with prolonged heparin therapy. Arch Intern Med. 2008 Jan 14; 168(1):94-102. PMID: 18195201.
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    143. Buergler JM, Alam S, Spencer W, Kleiman NS, Melendez Y, Franklin J, Nagueh SF. Initial experience with alcohol septal ablation using a novel magnetic navigation system. J Interv Cardiol. 2007 Dec; 20(6):559-63. PMID: 18042061.
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    144. Tricoci P, Lokhnygina Y, Berdan LG, Steinhubl SR, Gulba DC, White HD, Kleiman NS, Aylward PE, Langer A, Califf RM, Ferguson JJ, Antman EM, Newby LK, Harrington RA, Goodman SG, Mahaffey KW. Time to coronary angiography and outcomes among patients with high-risk non ST-segment elevation acute coronary syndromes: results from the SYNERGY trial. Circulation. 2007 Dec 4; 116(23):2669-77. PMID: 18025532.
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    145. Lev EI, Arikan ME, Vaduganathan M, Alviar CL, Tellez A, Mathuria N, Builes A, Granada JF, del Conde I, Kleiman NS. Effect of caffeine on platelet inhibition by clopidogrel in healthy subjects and patients with coronary artery disease. Am Heart J. 2007 Oct; 154(4):694.e1-7. PMID: 17892993.
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    146. Patel RT, Lev EI, Vaduganathan M, Guthikonda S, Bergeron A, Maresh K, Dong JF, Kleiman NS. Platelet reactivity among Asian Indians and Caucasians. Platelets. 2007 Jun; 18(4):261-5. PMID: 17538846.
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    147. Win HK, Caldera AE, Maresh K, Lopez J, Rihal CS, Parikh MA, Granada JF, Marulkar S, Nassif D, Cohen DJ, Kleiman NS. Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents. JAMA. 2007 May 9; 297(18):2001-9. PMID: 17488965.
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    148. Grossman PM, Mendelsohn F, Henry TD, Hermiller JB, Litt M, Saucedo JF, Weiss RJ, Kandzari DE, Kleiman N, Anderson RD, Gottlieb D, Karlsberg R, Snell J, Rocha-Singh K. Results from a phase II multicenter, double-blind placebo-controlled study of Del-1 (VLTS-589) for intermittent claudication in subjects with peripheral arterial disease. Am Heart J. 2007 May; 153(5):874-80. PMID: 17452167.
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    149. Dzavík V, Cotter G, Reynolds HR, Alexander JH, Ramanathan K, Stebbins AL, Hathaway D, Farkouh ME, Ohman EM, Baran DA, Prondzinsky R, Panza JA, Cantor WJ, Vered Z, Buller CE, Kleiman NS, Webb JG, Holmes DR, Parrillo JE, Hazen SL, Gross SS, Harrington RA, Hochman JS. Effect of nitric oxide synthase inhibition on haemodynamics and outcome of patients with persistent cardiogenic shock complicating acute myocardial infarction: a phase II dose-ranging study. Eur Heart J. 2007 May; 28(9):1109-16. PMID: 17459901.
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    150. Guthikonda S, Lev EI, Patel R, DeLao T, Bergeron AL, Dong JF, Kleiman NS. Reticulated platelets and uninhibited COX-1 and COX-2 decrease the antiplatelet effects of aspirin. J Thromb Haemost. 2007 Mar; 5(3):490-6. PMID: 17319904.
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    151. Lev EI, Ramchandani M, Garg R, Wojciechowski Z, Builes A, Vaduganathan M, Tripathy U, Kleiman NS. Response to aspirin and clopidogrel in patients scheduled to undergo cardiovascular surgery. J Thromb Thrombolysis. 2007 Aug; 24(1):15-21. PMID: 17277998.
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    152. Schweiger MJ, Chambers CE, Davidson CJ, Zhang S, Blankenship J, Bhalla NP, Block PC, Dervan JP, Gasperetti C, Gerber L, Kleiman NS, Krone RJ, Phillips WJ, Siegel RM, Uretsky BF, Laskey WK. Prevention of contrast induced nephropathy: recommendations for the high risk patient undergoing cardiovascular procedures. Catheter Cardiovasc Interv. 2007 Jan; 69(1):135-40. PMID: 17139671.
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    153. Lev EI, Alviar CL, Arikan ME, Dave BP, Granada JF, DeLao T, Tellez A, Maresh K, Kleiman NS. Platelet reactivity in patients with subacute stent thrombosis compared with non-stent-related acute myocardial infarction. Am Heart J. 2007 Jan; 153(1):41.e1-6. PMID: 17174635.
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    154. Cantor WJ, Mahaffey KW, Huang Z, Das P, Gulba DC, Glezer S, Gallo R, Ducas J, Cohen M, Antman EM, Langer A, Kleiman NS, White HD, Chisholm RJ, Harrington RA, Ferguson JJ, Califf RM, Goodman SG. Bleeding complications in patients with acute coronary syndrome undergoing early invasive management can be reduced with radial access, smaller sheath sizes, and timely sheath removal. Catheter Cardiovasc Interv. 2007 Jan; 69(1):73-83. PMID: 17139670.
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    155. White HD, Kleiman NS, Mahaffey KW, Lokhnygina Y, Pieper KS, Chiswell K, Cohen M, Harrington RA, Chew DP, Petersen JL, Berdan LG, Aylward PE, Nessel CC, Ferguson JJ, Califf RM. Efficacy and safety of enoxaparin compared with unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndrome undergoing percutaneous coronary intervention in the Superior Yield of the New Strategy of Enoxaparin, Revascularization and Glycoprotein IIb/IIIa Inhibitors (SYNERGY) trial. Am Heart J. 2006 Dec; 152(6):1042-50. PMID: 17161049.
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    156. Dyke CK, Steinhubl SR, Kleiman NS, Cannon RO, Aberle LG, Lin M, Myles SK, Melloni C, Harrington RA, Alexander JH, Becker RC, Rusconi CP. First-in-human experience of an antidote-controlled anticoagulant using RNA aptamer technology: a phase 1a pharmacodynamic evaluation of a drug-antidote pair for the controlled regulation of factor IXa activity. Circulation. 2006 Dec 5; 114(23):2490-7. PMID: 17101847.
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    157. Lev EI, Ramabadran RS, Guthikonda S, Patel R, Kleiman A, Granada JF, DeLao T, Kleiman NS. Effect of ranitidine on the antiplatelet effects of aspirin in healthy human subjects. Am J Cardiol. 2007 Jan 1; 99(1):124-8. PMID: 17196475.
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    158. Kleiman NS. Measuring troponin elevation after percutaneous coronary intervention: ready for prime time? J Am Coll Cardiol. 2006 Nov 7; 48(9):1771-3. PMID: 17084248.
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    159. Patel MR, Chen AY, Peterson ED, Newby LK, Pollack CV, Brindis RG, Gibson CM, Kleiman NS, Saucedo JF, Bhatt DL, Gibler WB, Ohman EM, Harrington RA, Roe MT. Prevalence, predictors, and outcomes of patients with non-ST-segment elevation myocardial infarction and insignificant coronary artery disease: results from the Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA Guidelines (CRUSADE) initiative. Am Heart J. 2006 Oct; 152(4):641-7. PMID: 16996828.
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    160. Lev EI, Estrov Z, Aboulfatova K, Harris D, Granada JF, Alviar C, Kleiman NS, Dong JF. Potential role of activated platelets in homing of human endothelial progenitor cells to subendothelial matrix. Thromb Haemost. 2006 Oct; 96(4):498-504. PMID: 17003929.
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    161. Exaire JE, Butman SM, Ebrahimi R, Kleiman NS, Harrington RA, Schweiger MJ, Bittl JA, Wolski K, Topol EJ, Lincoff AM. Provisional glycoprotein IIb/IIIa blockade in a randomized investigation of bivalirudin versus heparin plus planned glycoprotein IIb/IIIa inhibition during percutaneous coronary intervention: predictors and outcome in the Randomized Evaluation in Percutaneous coronary intervention Linking Angiomax to Reduced Clinical Events (REPLACE)-2 trial. Am Heart J. 2006 Jul; 152(1):157-63. PMID: 16824849.
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    162. Rajagopal V, Lincoff AM, Cohen DJ, Gurm HS, Hu T, Desmet WJ, Kleiman NS, Bittl JA, Feit F, Topol EJ. Outcomes of patients with acute coronary syndromes who are treated with bivalirudin during percutaneous coronary intervention: an analysis from the Randomized Evaluation in PCI Linking Angiomax to Reduced Clinical Events (REPLACE-2) trial. Am Heart J. 2006 Jul; 152(1):149-54. PMID: 16824845.
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    163. Lev EI, Tayyan N, Raizner AE, Solomon SL, Simmons D, Kleiman NS. Initial impact of drug-eluting stent use on the spectrum of patients undergoing percutaneous coronary intervention. Coron Artery Dis. 2006 May; 17(4):379-84. PMID: 16707962.
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    164. Blankenship JC, Haldis T, Feit F, Hu T, Kleiman NS, Topol EJ, Lincoff AM. Angiographic adverse events, creatine kinase-MB elevation, and ischemic end points complicating percutaneous coronary intervention (a REPLACE-2 substudy). Am J Cardiol. 2006 Jun 1; 97(11):1591-6. PMID: 16728220.
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    165. Lev EI, Patel RT, Guthikonda S, Lopez D, Bray PF, Kleiman NS. Genetic polymorphisms of the platelet receptors P2Y(12), P2Y(1) and GP IIIa and response to aspirin and clopidogrel. Thromb Res. 2007; 119(3):355-60. PMID: 16581111.
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    166. Lev EI, Patel R, Karim A, Kleiman A, Badimon JJ, Kleiman NS. Anti-thrombotic effect of bivalirudin compared with eptifibatide and unfractionated heparin in diabetic patients: an ex vivo human study. Thromb Haemost. 2006 Mar; 95(3):441-6. PMID: 16525571.
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    167. Ellis TC, Lev E, Yazbek NF, Kleiman NS. Therapeutic strategies for cardiogenic shock, 2006. Curr Treat Options Cardiovasc Med. 2006 Feb; 8(1):79-94. PMID: 16401386.
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    168. Atmakuri SR, Lev EI, Alviar C, Ibarra E, Raizner AE, Solomon SL, Kleiman NS. Initial experience with a magnetic navigation system for percutaneous coronary intervention in complex coronary artery lesions. J Am Coll Cardiol. 2006 Feb 7; 47(3):515-21. PMID: 16458129.
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    169. Guthikonda S, Kleiman NS. Is aspirin resistance valid? Future Cardiol. 2006 Jan; 2(1):1-4. PMID: 19804124.
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    170. Lev EI, Patel RT, Maresh KJ, Guthikonda S, Granada J, DeLao T, Bray PF, Kleiman NS. Aspirin and clopidogrel drug response in patients undergoing percutaneous coronary intervention: the role of dual drug resistance. J Am Coll Cardiol. 2006 Jan 3; 47(1):27-33. PMID: 16386660.
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    171. Mahaffey KW, Cohen M, Garg J, Antman E, Kleiman NS, Goodman SG, Berdan LG, Reist CJ, Langer A, White HD, Aylward PE, Col JJ, Ferguson JJ, Califf RM. High-risk patients with acute coronary syndromes treated with low-molecular-weight or unfractionated heparin: outcomes at 6 months and 1 year in the SYNERGY trial. JAMA. 2005 Nov 23; 294(20):2594-600. PMID: 16304073.
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    172. Jacob S, Cohen DJ, Massaro J, Niemyski P, Maresh K, Kleiman N. Design of a registry to characterize "real-world" outcomes of percutaneous coronary revascularization in the drug-eluting stent era. Am Heart J. 2005 Nov; 150(5):887-92. PMID: 16290954.
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    173. Kleiman NS, White HD. The declining prevalence of ST elevation myocardial infarction in patients presenting with acute coronary syndromes. Heart. 2005 Sep; 91(9):1121-3. PMID: 16103531; PMCID: PMC1769107.
    174. Lev EI, Kleiman NS, Birnbaum Y, Harris D, Korbling M, Estrov Z. Circulating endothelial progenitor cells and coronary collaterals in patients with non-ST segment elevation myocardial infarction. J Vasc Res. 2005 Sep-Oct; 42(5):408-14. PMID: 16088214.
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    175. Guthikonda S, Lev EI, Kleiman NS. Resistance to antiplatelet therapy. Curr Cardiol Rep. 2005 Jul; 7(4):242-8. PMID: 15987620.
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    176. Kleiman NS. Could clopidogrel's platelet inhibition be enhanced by an increased loading dose and eptifibatide? Nat Clin Pract Cardiovasc Med. 2005 Jul; 2(7):344-5. PMID: 16265559.
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    177. Gurm HS, Sarembock IJ, Kereiakes DJ, Young JJ, Harrington RA, Kleiman N, Feit F, Wolski K, Bittl JA, Wilcox R, Topol EJ, Lincoff AM. Use of bivalirudin during percutaneous coronary intervention in patients with diabetes mellitus: an analysis from the randomized evaluation in percutaneous coronary intervention linking angiomax to reduced clinical events (REPLACE)-2 trial. J Am Coll Cardiol. 2005 Jun 21; 45(12):1932-8. PMID: 15963389.
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    178. Mahaffey KW, Roe MT, Kilaru R, French JK, Alexander JH, Berdan LG, Van De Werf F, Simoons ML, Weaver WD, White HD, Lincoff AM, Kleiman NS, Topol EJ, Harrington RA. Characterization of myocardial infarction as an end point in two large trials of acute coronary syndromes. Am J Cardiol. 2005 Jun 15; 95(12):1404-8. PMID: 15950560.
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    179. Buergler JM, Maliszewski CR, Broekman MJ, Kaluza GL, Schulz DG, Marcus AJ, Raizner AE, Kleiman NS, Ali NM. Effects of SolCD39, a novel inhibitor of Platelet Aggregation, on Platelet Deposition and Aggregation after PTCA in a Porcine Model. J Thromb Thrombolysis. 2005 Apr; 19(2):115-22. PMID: 16052302.
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    180. Alexander JH, Yang H, Becker RC, Kodama K, Goodman S, Dyke CK, Kleiman NS, Hochman JS, Berger PB, Cohen EA, Lincoff AM, Burton JR, Bovill EG, Kawai C, Armstrong PW, Harrington RA. First experience with direct, selective factor Xa inhibition in patients with non-ST-elevation acute coronary syndromes: results of the XaNADU-ACS Trial. J Thromb Haemost. 2005 Mar; 3(3):439-47. PMID: 15748230.
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    181. Exaire JE, Tcheng JE, Kereiakes DJ, Kleiman NS, Applegate RJ, Moliterno DJ. Closure devices and vascular complications among percutaneous coronary intervention patients receiving enoxaparin, glycoprotein IIb/IIIa inhibitors, and clopidogrel. Catheter Cardiovasc Interv. 2005 Mar; 64(3):369-72. PMID: 15736260.
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    182. del Conde I, Nabi F, Tonda R, Thiagarajan P, López JA, Kleiman NS. Effect of P-selectin on phosphatidylserine exposure and surface-dependent thrombin generation on monocytes. Arterioscler Thromb Vasc Biol. 2005 May; 25(5):1065-70. PMID: 15705928.
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    183. Ohman EM, Granger CB, Rice L, Abrams CS, Becker RC, Berger PB, Kleiman NS, Moliterno D, Moll S, Rodgers JE, Steinhubl SS, Tapson VF, Sinnaeve P, Anstrom KJ. Identification, diagnosis and treatment of heparin-induced thrombocytopenia and thrombosis: a registry of prolonged heparin use and thrombocytopenia among hospitalized patients with and without cardiovascular disease. The Complication After Thrombocytopenia Caused by Heparin (CATCH) Registry steering committee. J Thromb Thrombolysis. 2005 Feb; 19(1):11-9. PMID: 15976962.
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    184. Prahash A, Kleiman N, Espada R, Dokainish H. Idiopathic sinus of Valsalva to right atrial fistula: an unusual origin of right-sided heart failure. J Am Soc Echocardiogr. 2004 Dec; 17(12):1317-8. PMID: 15562275.
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    185. Bhatt DL, Roe MT, Peterson ED, Li Y, Chen AY, Harrington RA, Greenbaum AB, Berger PB, Cannon CP, Cohen DJ, Gibson CM, Saucedo JF, Kleiman NS, Hochman JS, Boden WE, Brindis RG, Peacock WF, Smith SC, Pollack CV, Gibler WB, Ohman EM. Utilization of early invasive management strategies for high-risk patients with non-ST-segment elevation acute coronary syndromes: results from the CRUSADE Quality Improvement Initiative. JAMA. 2004 Nov 3; 292(17):2096-104. PMID: 15523070.
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    186. Cox DS, Kleiman NS, Boyle DA, Aluri J, Parchman LG, Holdbrook F, Fossler MJ. Pharmacokinetics and pharmacodynamics of argatroban in combination with a platelet glycoprotein IIB/IIIA receptor antagonist in patients undergoing percutaneous coronary intervention. J Clin Pharmacol. 2004 Sep; 44(9):981-90. PMID: 15317826.
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    187. Lincoff AM, Kleiman NS, Kereiakes DJ, Feit F, Bittl JA, Jackman JD, Sarembock IJ, Cohen DJ, Spriggs D, Ebrahimi R, Keren G, Carr J, Cohen EA, Betriu A, Desmet W, Rutsch W, Wilcox RG, de Feyter PJ, Vahanian A, Topol EJ. Long-term efficacy of bivalirudin and provisional glycoprotein IIb/IIIa blockade vs heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary revascularization: REPLACE-2 randomized trial. JAMA. 2004 Aug 11; 292(6):696-703. PMID: 15304466.
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    188. Petersen JL, Mahaffey KW, Becker RC, Goodman SG, Kleiman NS, Marian AJ, Stone GW, Lansky AJ, Lincoff AM, Hazen SL, Nessel CC, Toro-Figueroa L, Tate L, Reist CJ, Cohen M, Califf RM, Ferguson JJ. Coordinated series of studies to evaluate characteristics and mechanisms of acute coronary syndromes in high-risk patients randomly assigned to enoxaparin or unfractionated heparin: design and rationale of the SYNERGY Library. Am Heart J. 2004 Aug; 148(2):269-76. PMID: 15308996.
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    189. Jang IK, Lewis BE, Matthai WH, Kleiman NS. Argatroban anticoagulation in conjunction with glycoprotein IIb/IIIa inhibition in patients undergoing percutaneous coronary intervention: an open-label, nonrandomized pilot study. J Thromb Thrombolysis. 2004 Aug; 18(1):31-7. PMID: 15744551.
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    190. Rajagopal V, Gurm HS, Bhatt DL, Lincoff AM, Tcheng JE, Kereiakes DJ, Kleiman NS, Jia G, Topol EJ. Relation of an elevated white blood cell count after percutaneous coronary intervention to long-term mortality. Am J Cardiol. 2004 Jul 15; 94(2):190-2. PMID: 15246898.
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    191. Ferguson JJ, Califf RM, Antman EM, Cohen M, Grines CL, Goodman S, Kereiakes DJ, Langer A, Mahaffey KW, Nessel CC, Armstrong PW, Avezum A, Aylward P, Becker RC, Biasucci L, Borzak S, Col J, Frey MJ, Fry E, Gulba DC, Guneri S, Gurfinkel E, Harrington R, Hochman JS, Kleiman NS, Leon MB, Lopez-Sendon JL, Pepine CJ, Ruzyllo W, Steinhubl SR, Teirstein PS, Toro-Figueroa L, White H. Enoxaparin vs unfractionated heparin in high-risk patients with non-ST-segment elevation acute coronary syndromes managed with an intended early invasive strategy: primary results of the SYNERGY randomized trial. JAMA. 2004 Jul 7; 292(1):45-54. PMID: 15238590.
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    192. Chang WC, Boersma E, Granger CB, Harrington RA, Califf RM, Simoons ML, Kleiman NS, Armstrong PW. Dynamic prognostication in non-ST-elevation acute coronary syndromes: insights from GUSTO-IIb and PURSUIT. Am Heart J. 2004 Jul; 148(1):62-71. PMID: 15215793.
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    193. Kleiman NS. Platelets, the cardiologist, and coronary artery disease: moving beyond aggregation. J Am Coll Cardiol. 2004 Jun 2; 43(11):1989-91. PMID: 15172402.
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    194. Dakik HA, Koubeissi Z, Kleiman NS, Nasrallah A, Sawaya J, Gharzuddine W, Tamim H, Shaar K, Alam S. Acute myocardial infarction: clinical characteristics, management and outcome in a university medical centre in a developing Middle Eastern country. Can J Cardiol. 2004 Jun; 20(8):789-93. PMID: 15229760.
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    195. Labinaz M, Kaul P, Harrington RA, Chang WC, Kleiman NS, Simoons ML, Boersma E, Akkerhuis KM, Califf RM, Armstrong PW. Six-month outcomes of percutaneous coronary balloon angioplasty in acute coronary syndromes: Results from the PURSUIT trial. Can J Cardiol. 2004 Jun; 20(8):773-8. PMID: 15229770.
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    196. Lincoff AM, Bittl JA, Kleiman NS, Sarembock IJ, Jackman JD, Mehta S, Tannenbaum MA, Niederman AL, Bachinsky WB, Tift-Mann J, Parker HG, Kereiakes DJ, Harrington RA, Feit F, Maierson ES, Chew DP, Topol EJ. Comparison of bivalirudin versus heparin during percutaneous coronary intervention (the Randomized Evaluation of PCI Linking Angiomax to Reduced Clinical Events [REPLACE]-1 trial). Am J Cardiol. 2004 May 1; 93(9):1092-6. PMID: 15110198.
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    197. Quinn MJ, Aronow HD, Califf RM, Bhatt DL, Sapp S, Kleiman NS, Harrington RA, Kong DF, Kandzari DE, Topol EJ. Aspirin dose and six-month outcome after an acute coronary syndrome. J Am Coll Cardiol. 2004 Mar 17; 43(6):972-8. PMID: 15028352.
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    198. Pieper KS, Tsiatis AA, Davidian M, Hasselblad V, Kleiman NS, Boersma E, Chang WC, Griffin J, Armstrong PW, Califf RM, Harrington RA. Differential treatment benefit of platelet glycoprotein IIb/IIIa inhibition with percutaneous coronary intervention versus medical therapy for acute coronary syndromes: exploration of methods. Circulation. 2004 Feb 10; 109(5):641-6. PMID: 14769687.
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    199. Conde ID, Kleiman NS. Patient-specific antiplatelet therapy. J Thromb Thrombolysis. 2004 Feb; 17(1):63-77. PMID: 15277789.
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    200. Alexander JH, Dyke CK, Yang H, Becker RC, Hasselblad V, Zillman LA, Kleiman NS, Hochman JS, Berger PB, Cohen EA, Lincoff AM, Saint-Jacques H, Chetcuti S, Burton JR, Buergler JM, Spence FP, Shimoto Y, Robertson TL, Kunitada S, Bovill EG, Armstrong PW, Harrington RA. Initial experience with factor-Xa inhibition in percutaneous coronary intervention: the XaNADU-PCI Pilot. J Thromb Haemost. 2004 Feb; 2(2):234-41. PMID: 14995984.
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    201. Yazbek NF, Kleiman NS. Therapeutic Strategies for Cardiogenic Shock. Curr Treat Options Cardiovasc Med. 2004 Feb; 6(1):29-41. PMID: 15023282.
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    202. Urquidi-Macdonald M, Mager DE, Mascelli MA, Frederick B, Freedman J, Fitzgerald DJ, Kleiman NS, Abernethy DR. Abciximab pharmacodynamic model with neural networks used to integrate sources of patient variability. Clin Pharmacol Ther. 2004 Jan; 75(1):60-9. PMID: 14749692.
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    203. Granada JF, Kleiman NS. Therapeutic use of intravenous eptifibatide in patients undergoing percutaneous coronary intervention: acute coronary syndromes and elective stenting. Am J Cardiovasc Drugs. 2004; 4(1):31-41. PMID: 14967064.
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    204. Grines C, Rubanyi GM, Kleiman NS, Marrott P, Watkins MW. Angiogenic gene therapy with adenovirus 5 fibroblast growth factor-4 (Ad5FGF-4): a new option for the treatment of coronary artery disease. Am J Cardiol. 2003 Nov 7; 92(9B):24N-31N. PMID: 14615023.
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    205. Kleiman NS, Patel NC, Allen KB, Simons M, Ylä-Herttuala S, Griffin E, Dzau VJ. Evolving revascularization approaches for myocardial ischemia. Am J Cardiol. 2003 Nov 7; 92(9B):9N-17N. PMID: 14615021.
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    206. Grines CL, Watkins MW, Mahmarian JJ, Iskandrian AE, Rade JJ, Marrott P, Pratt C, Kleiman N. A randomized, double-blind, placebo-controlled trial of Ad5FGF-4 gene therapy and its effect on myocardial perfusion in patients with stable angina. J Am Coll Cardiol. 2003 Oct 15; 42(8):1339-47. PMID: 14563572.
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    207. Mager DE, Mascelli MA, Kleiman NS, Fitzgerald DJ, Abernethy DR. Simultaneous modeling of abciximab plasma concentrations and ex vivo pharmacodynamics in patients undergoing coronary angioplasty. J Pharmacol Exp Ther. 2003 Dec; 307(3):969-76. PMID: 14534354.
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    208. Conde ID, Kleiman NS. Arterial thrombosis for the interventional cardiologist: from adhesion molecules and coagulation factors to clinical therapeutics. Catheter Cardiovasc Interv. 2003 Oct; 60(2):236-46. PMID: 14517933.
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    209. Gurm HS, Bhatt DL, Lincoff AM, Tcheng JE, Kereiakes DJ, Kleiman NS, Jia G, Topol EJ. Impact of preprocedural white blood cell count on long term mortality after percutaneous coronary intervention: insights from the EPIC, EPILOG, and EPISTENT trials. Heart. 2003 Oct; 89(10):1200-4. PMID: 12975419; PMCID: PMC1767915.
    210. Moliterno DJ, Hermiller JB, Kereiakes DJ, Yow E, Applegate RJ, Braden GA, Dippel EJ, Furman MI, Grines CL, Kleiman NS, Levine GN, Mann T, Nair RN, Stine RA, Yacubov SJ, Tcheng JE. A novel point-of-care enoxaparin monitor for use during percutaneous coronary intervention. Results of the Evaluating Enoxaparin Clotting Times (ELECT) Study. J Am Coll Cardiol. 2003 Sep 17; 42(6):1132-9. PMID: 13678943.
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    211. Becker R, Butenas S, Carr M, Jaffer F, Kleiman NS, Marmur JD, Schneider DJ, Spiess BD, Steinhubl SR, Weitz JI. Bivalirudin, thrombin and platelets: clinical implications and future directions. J Invasive Cardiol. 2003 Aug; Suppl:2-15. PMID: 23570139.
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    212. Yazbek N, Bapat A, Kleiman N. Platelet abnormalities in diabetes mellitus. Coron Artery Dis. 2003 Aug; 14(5):365-71. PMID: 12878901.
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    213. Conde ID, Kleiman NS. Soluble CD40 ligand in acute coronary syndromes. N Engl J Med. 2003 Jun 19; 348(25):2575-7; author reply 2575-7. PMID: 12816111.
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    214. Kleiman NS. Combination therapy for acute myocardial infarction: will it survive? J Am Coll Cardiol. 2003 Apr 16; 41(8):1261-3. PMID: 12706918.
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    215. Nguyen-Ho P, Kleiman NS, Verani MS. Acute myocardial infarction and cardiac arrest in a patient receiving paclitaxel. Can J Cardiol. 2003 Mar 15; 19(3):300-2. PMID: 12677287.
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    216. Lincoff AM, Bittl JA, Harrington RA, Feit F, Kleiman NS, Jackman JD, Sarembock IJ, Cohen DJ, Spriggs D, Ebrahimi R, Keren G, Carr J, Cohen EA, Betriu A, Desmet W, Kereiakes DJ, Rutsch W, Wilcox RG, de Feyter PJ, Vahanian A, Topol EJ. Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial. JAMA. 2003 Feb 19; 289(7):853-63. PMID: 12588269.
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    217. Fernandes LS, Conde ID, Wayne Smith C, Kansas GS, Snapp KR, Bennet N, Ballantyne C, McIntire LV, O'Brian Smith E, Klem JA, Mathew S, Frangogiannis N, Turner NA, Maresh KJ, Kleiman NS. Platelet-monocyte complex formation: effect of blocking PSGL-1 alone, and in combination with alphaIIbbeta3 and alphaMbeta2, in coronary stenting. Thromb Res. 2003; 111(3):171-7. PMID: 14678816.
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    218. Kereiakes DJ, Montalescot G, Antman EM, Cohen M, Darius H, Ferguson JJ, Grines C, Karsch KR, Kleiman NS, Moliterno DJ, Steg PG, Teirstein P, Van de Werf F, Wallentin L. Low-molecular-weight heparin therapy for non-ST-elevation acute coronary syndromes and during percutaneous coronary intervention: an expert consensus. Am Heart J. 2002 Oct; 144(4):615-24. PMID: 12360156.
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    219. Kleiman NS, Lakkis N, Cannon CP, Murphy SA, DiBattiste PM, Demopoulos LA, Weintraub WS, Braunwald E. Prospective analysis of creatine kinase muscle-brain fraction and comparison with troponin T to predict cardiac risk and benefit of an invasive strategy in patients with non-ST-elevation acute coronary syndromes. J Am Coll Cardiol. 2002 Sep 18; 40(6):1044-50. PMID: 12354426.
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    220. Fernandes LS, Tcheng JE, O'Shea JC, Weiner B, Lorenz TJ, Pacchiana C, Berdan LG, Maresh KJ, Joseph D, Madan M, Mann T, Kilaru R, Hochman JS, Kleiman NS. Is glycoprotein IIb/IIIa antagonism as effective in women as in men following percutaneous coronary intervention?. Lessons from the ESPRIT study. J Am Coll Cardiol. 2002 Sep 18; 40(6):1085-91. PMID: 12354432.
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    221. Roffi M, Chew DP, Mukherjee D, Bhatt DL, White JA, Moliterno DJ, Heeschen C, Hamm CW, Robbins MA, Kleiman NS, Théroux P, White HD, Topol EJ. Platelet glycoprotein IIb/IIIa inhibition in acute coronary syndromes. Gradient of benefit related to the revascularization strategy. Eur Heart J. 2002 Sep; 23(18):1441-8. PMID: 12208224.
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    222. Topol EJ, Lincoff AM, Kereiakes DJ, Kleiman NS, Cohen EA, Ferguson JJ, Tcheng JE, Sapp S, Califf RM. Multi-year follow-up of abciximab therapy in three randomized, placebo-controlled trials of percutaneous coronary revascularization. Am J Med. 2002 Jul; 113(1):1-6. PMID: 12106616.
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    223. Dyke CK, Becker RC, Kleiman NS, Hochman JS, Bovill EG, Lincoff AM, Gerstenblith G, Dzavik V, Gardner LH, Hasselblad V, Zillman LA, Shimoto Y, Robertson TL, Kunitada S, Armstrong PW, Harrington RA. First experience with direct factor Xa inhibition in patients with stable coronary disease: a pharmacokinetic and pharmacodynamic evaluation. Circulation. 2002 May 21; 105(20):2385-91. PMID: 12021225.
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    224. Lincoff AM, Kleiman NS, Kottke-Marchant K, Maierson ES, Maresh K, Wolski KE, Topol EJ. Bivalirudin with planned or provisional abciximab versus low-dose heparin and abciximab during percutaneous coronary revascularization: results of the Comparison of Abciximab Complications with Hirulog for Ischemic Events Trial (CACHET). Am Heart J. 2002 May; 143(5):847-53. PMID: 12040347.
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    225. Kleiman NS. Antiplatelet therapy and coronary interventions: childhood friends or permanent partners? J Interv Cardiol. 2002 Apr; 15(2):111-3. PMID: 12063805.
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    226. Kleiman NS, Klem J, Fernandes LS, Rubin H, Challa S, Solomon S, Maresh K, Arora U, Klem E, Buergler J, Mathew S, Browning A, DeLao T. Pharmacodynamic profile of the direct thrombin antagonist bivalirudin given in combination with the glycoprotein IIb/IIIa antagonist eptifibatide. Am Heart J. 2002 Apr; 143(4):585-93. PMID: 11923794.
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    227. Arora UK, Conde I, Kleiman NS. Glycoprotein IIb/IIIa antagonists in the setting of rescue percutaneous coronary intervention. J Interv Cardiol. 2002 Apr; 15(2):155-62. PMID: 12063811.
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    228. Mazur W, Kaluza GL, Sapp S, Balog C, Topol EJ, Mark DB, Ellis SG, Kereiakes DJ, Lincoff AM, Kleiman NS. Glycoprotein IIb-IIIa inhibition with abciximab and postprocedural risk assessment: lessons from the evaluation of platelet IIb/IIIa inhibitor for stenting trial and implication for ad hoc use of glycoprotein IIb-IIIa antagonists. Am Heart J. 2002 Apr; 143(4):594-601. PMID: 11923795.
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    229. Abernethy DR, Pezzullo J, Mascelli MA, Frederick B, Kleiman NS, Freedman J. Pharmacodynamics of abciximab during angioplasty: comparison to healthy subjects. Clin Pharmacol Ther. 2002 Mar; 71(3):186-95. PMID: 11907493.
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    230. Simons M, Annex BH, Laham RJ, Kleiman N, Henry T, Dauerman H, Udelson JE, Gervino EV, Pike M, Whitehouse MJ, Moon T, Chronos NA. Pharmacological treatment of coronary artery disease with recombinant fibroblast growth factor-2: double-blind, randomized, controlled clinical trial. Circulation. 2002 Feb 19; 105(7):788-93. PMID: 11854116.
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    231. O'Shea JC, Buller CE, Cantor WJ, Chandler AB, Cohen EA, Cohen DJ, Gilchrist IC, Kleiman NS, Labinaz M, Madan M, Hafley GE, Califf RM, Kitt MM, Strony J, Tcheng JE. Long-term efficacy of platelet glycoprotein IIb/IIIa integrin blockade with eptifibatide in coronary stent intervention. JAMA. 2002 Feb 6; 287(5):618-21. PMID: 11829701.
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    232. Ronner E, Boersma E, Akkerhuis KM, Harrington RA, Lincoff AM, Deckers JW, Karsch K, Kleiman NS, Vahanian A, Topol EJ, Califf RM, Simoons ML. Patients with acute coronary syndromes without persistent ST elevation undergoing percutaneous coronary intervention benefit most from early intervention with protection by a glycoprotein IIb/IIIa receptor blocker. Eur Heart J. 2002 Feb; 23(3):239-46. PMID: 11792139.
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    233. Mahaffey KW, Roe MT, Dyke CK, Newby LK, Kleiman NS, Connolly P, Berdan LG, Sparapani R, Lee KL, Armstrong PW, Topol EJ, Califf RM, Harrington RA. Misreporting of myocardial infarction end points: results of adjudication by a central clinical events committee in the PARAGON-B trial. Second Platelet IIb/IIIa Antagonist for the Reduction of Acute Coronary Syndrome Events in a Global Organization Network Trial. Am Heart J. 2002 Feb; 143(2):242-8. PMID: 11835026.
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    234. Kleiman NS. Antiplatelet therapy and coronary interventions: childhood friends or permanent partners? J Interv Cardiol. 2002 Feb; 15(1):41-3. PMID: 12053683.
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    235. Roffi M, Chew DP, Mukherjee D, Bhatt DL, White JA, Heeschen C, Hamm CW, Moliterno DJ, Califf RM, White HD, Kleiman NS, Théroux P, Topol EJ. Platelet glycoprotein IIb/IIIa inhibitors reduce mortality in diabetic patients with non-ST-segment-elevation acute coronary syndromes. Circulation. 2001 Dec 4; 104(23):2767-71. PMID: 11733392.
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    236. Tcheng JE, Talley JD, O'Shea JC, Gilchrist IC, Kleiman NS, Grines CL, Davidson CJ, Lincoff AM, Califf RM, Jennings LK, Kitt MM, Lorenz TJ. Clinical pharmacology of higher dose eptifibatide in percutaneous coronary intervention (the PRIDE study). Am J Cardiol. 2001 Nov 15; 88(10):1097-102. PMID: 11703951.
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    237. Tcheng JE, Kereiakes DJ, Lincoff AM, George BS, Kleiman NS, Sane DC, Cines DB, Jordan RE, Mascelli MA, Langrall MA, Damaraju L, Schantz A, Effron MB, Braden GA. Abciximab readministration: results of the ReoPro Readministration Registry. Circulation. 2001 Aug 21; 104(8):870-5. PMID: 11514371.
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    238. Gilchrist IC, O'Shea JC, Kosoglou T, Jennings LK, Lorenz TJ, Kitt MM, Kleiman NS, Talley D, Aguirre F, Davidson C, Runyon J, Tcheng JE. Pharmacodynamics and pharmacokinetics of higher-dose, double-bolus eptifibatide in percutaneous coronary intervention. Circulation. 2001 Jul 24; 104(4):406-11. PMID: 11468201.
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    239. Tardiff BE, Jennings LK, Harrington RA, Gretler D, Potthoff RF, Vorchheimer DA, Eisenberg PR, Lincoff AM, Labinaz M, Joseph DM, McDougal MF, Kleiman NS. Pharmacodynamics and pharmacokinetics of eptifibatide in patients with acute coronary syndromes: prospective analysis from PURSUIT. Circulation. 2001 Jul 24; 104(4):399-405. PMID: 11468200.
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    240. Mahaffey KW, Harrington RA, Akkerhuis M, Kleiman NS, Berdan LG, Crenshaw BS, Tardiff BE, Granger CB, DeJong I, Bhapkar M, Widimsky P, Corbalon R, Lee KL, Deckers JW, Simoons ML, Topol EJ, Califf RM. Systematic adjudication of myocardial infarction end-points in an international clinical trial. Curr Control Trials Cardiovasc Med. 2001 Jul 17; 2(4):180-186. PMID: 11806793.
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    241. Mahaffey KW, Harrington RA, Akkerhuis M, Kleiman NS, Berdan LG, Crenshaw BS, Tardiff BE, Granger CB, DeJong I, Bhapkar M, Widimsky P, Corbalon R, Lee KL, Deckers JW, Simoons ML, Topol EJ, Califf RM. Disagreements between central clinical events committee and site investigator assessments of myocardial infarction endpoints in an international clinical trial: review of the PURSUIT study. Curr Control Trials Cardiovasc Med. 2001 Jul 17; 2(4):187-194. PMID: 11806794.
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    242. Aguilar OM, Kleiman NS. Low-molecular-weight heparins. J Invasive Cardiol. 2001 May; 13 Suppl A:3A-7A. PMID: 11458011.
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    243. Aronow HD, Topol EJ, Roe MT, Houghtaling PL, Wolski KE, Lincoff AM, Harrington RA, Califf RM, Ohman EM, Kleiman NS, Keltai M, Wilcox RG, Vahanian A, Armstrong PW, Lauer MS. Effect of lipid-lowering therapy on early mortality after acute coronary syndromes: an observational study. Lancet. 2001 Apr 7; 357(9262):1063-8. PMID: 11297956.
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    244. Kereiakes DJ, Kleiman NS, Fry E, Mwawasi G, Lengerich R, Maresh K, Burkert ML, Aquilina JW, DeLoof M, Broderick TM, Shimshak TM. Dalteparin in combination with abciximab during percutaneous coronary intervention. Am Heart J. 2001 Mar; 141(3):348-52. PMID: 11231430.
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    245. Marso SP, Bhatt DL, Roe MT, Houghtaling PL, Labinaz M, Kleiman NS, Dyke C, Simmoons ML, Califf RM, Harrington RA, Topol EJ. Enhanced efficacy of eptifibatide administration in patients with acute coronary syndrome requiring in-hospital coronary artery bypass grafting. PURSUIT Investigators. Circulation. 2000 Dec 12; 102(24):2952-8. PMID: 11113045.
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    246. Kleiman NS, Weitz JI. Putting heparin into perspective: its history and the evolution of its use during percutaneous coronary interventions. J Invasive Cardiol. 2000 Dec; 12 Suppl F:20F-6. PMID: 11156730.
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    247. Lincoff AM, Harrington RA, Califf RM, Hochman JS, Guerci AD, Ohman EM, Pepine CJ, Kopecky SL, Kleiman NS, Pacchiana CM, Berdan LG, Kitt MM, Simoons ML, Topol EJ. Management of patients with acute coronary syndromes in the United States by platelet glycoprotein IIb/IIIa inhibition. Insights from the platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial. Circulation. 2000 Sep 5; 102(10):1093-100. PMID: 10973836.
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    248. Kleiman NS, Grazeiadei N, Maresh K, Taylor RJ, Frederick B, Lance ET, Effron MB, Jordan RE, Mascelli MA. Abciximab, ticlopidine, and concomitant abciximab-ticlopidine therapy: ex vivo platelet aggregation inhibition profiles in patients undergoing percutaneous coronary interventions. Am Heart J. 2000 Sep; 140(3):492-501. PMID: 10966553.
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    249. Aguilar OM, Kleiman NS. Low molecular weight heparins. Expert Opin Pharmacother. 2000 Sep; 1(6):1091-103. PMID: 11249481.
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    250. Conde-Pozzi I, Kleiman N. Platelet activation in acute myocardial infarction and the rationale for combination therapy. Curr Cardiol Rep. 2000 Sep; 2(5):378-85. PMID: 10980904.
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    251. Cho L, Topol EJ, Balog C, Foody JM, Booth JE, Cabot C, Kleiman NS, Tcheng JE, Califf R, Lincoff AM. Clinical benefit of glycoprotein IIb/IIIa blockade with Abciximab is independent of gender: pooled analysis from EPIC, EPILOG and EPISTENT trials. Evaluation of 7E3 for the Prevention of Ischemic Complications. Evaluation in Percutaneous Transluminal Coronary Angioplasty to Improve Long-Term Outcome with Abciximab GP IIb/IIIa blockade. Evaluation of Platelet IIb/IIIa Inhibitor for Stent. J Am Coll Cardiol. 2000 Aug; 36(2):381-6. PMID: 10933346.
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    252. Kleiman NS, Califf RM. Results from late-breaking clinical trials sessions at ACCIS 2000 and ACC 2000. American College of Cardiology. J Am Coll Cardiol. 2000 Jul; 36(1):310-25. PMID: 10898457.
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    253. Coulter SA, Cannon CP, Ault KA, Antman EM, Van de Werf F, Adgey AA, Gibson CM, Giugliano RP, Mascelli MA, Scherer J, Barnathan ES, Braunwald E, Kleiman NS. High levels of platelet inhibition with abciximab despite heightened platelet activation and aggregation during thrombolysis for acute myocardial infarction: results from TIMI (thrombolysis in myocardial infarction) 14. Circulation. 2000 Jun 13; 101(23):2690-5. PMID: 10851205.
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    254. Mascelli MA, Kleiman NS, Marciniak SJ, Damaraju L, Weisman HF, Jordan RE. Therapeutic heparin concentrations augment platelet reactivity: implications for the pharmacologic assessment of the glycoprotein IIb/IIIa antagonist abciximab. Am Heart J. 2000 Apr; 139(4):696-703. PMID: 10740154.
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    255. Batchelor WB, Granger CB, Kleiman NS, Phillips HR, Ellis SG, Betriu A, Criger DA, Stebbins AL, Topol EJ, Califf RM. A comparison of ionic versus nonionic contrast medium during primary percutaneous transluminal coronary angioplasty for acute myocardial infarction (GUSTO IIb). Global Use of Strategies to Open Occluded Coronary Arteries in Acute Coronary Syndromes. Am J Cardiol. 2000 Mar 15; 85(6):692-7. PMID: 12000041.
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    256. Fredrickson BJ, Turner NA, Kleiman NS, Graziadei N, Maresh K, Mascelli MA, Effron MB, McIntire LV. Effects of abciximab, ticlopidine, and combined Abciximab/Ticlopidine therapy on platelet and leukocyte function in patients undergoing coronary angioplasty. Circulation. 2000 Mar 14; 101(10):1122-9. PMID: 10715258.
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    257. Kleiman NS, Lincoff AM, Flaker GC, Pieper KS, Wilcox RG, Berdan LG, Lorenz TJ, Cokkinos DV, Simoons ML, Boersma E, Topol EJ, Califf RM, Harrington RA. Early percutaneous coronary intervention, platelet inhibition with eptifibatide, and clinical outcomes in patients with acute coronary syndromes. PURSUIT Investigators. Circulation. 2000 Feb 22; 101(7):751-7. PMID: 10683348.
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    258. Kleiman NS, Tracy RP, Talley JD, Sigmon K, Joseph D, Topol EJ, Califf RM, Kitt M, Ohman EM. Inhibition of platelet aggregation with a glycoprotein IIb-IIIa antagonist does not prevent thrombin generation in patients undergoing thrombolysis for acute myocardial infarction. J Thromb Thrombolysis. 2000 Jan; 9(1):5-12. PMID: 10590183.
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    259. Kleiman NS, Graziadei N, Jordan RE, Lance ET, Fischer A, Maresh K, Edwards A, Mascelli MA. Ticlopidine enhances the platelet inhibitory capacity of abciximab in vitro. J Thromb Thrombolysis. 2000 Jan; 9(1):29-36. PMID: 10590186.
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    260. Braunwald E, Califf RM, Cannon CP, Fox KA, Fuster V, Gibler WB, Harrington RA, King SB, Kleiman NS, Theroux P, Topol EJ, Van de Werf F, White HD, Willerson JT. Redefining medical treatment in the management of unstable angina. Am J Med. 2000 Jan; 108(1):41-53. PMID: 11059440.
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    261. Crenshaw BS, Granger CB, Birnbaum Y, Pieper KS, Morris DC, Kleiman NS, Vahanian A, Califf RM, Topol EJ. Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. GUSTO-I (Global Utilization of Streptokinase and TPA for Occluded Coronary Arteries) Trial Investigators. Circulation. 2000 Jan 4-11; 101(1):27-32. PMID: 10618300.
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    262. Topol EJ, Mark DB, Lincoff AM, Cohen E, Burton J, Kleiman N, Talley D, Sapp S, Booth J, Cabot CF, Anderson KM, Califf RM. Outcomes at 1 year and economic implications of platelet glycoprotein IIb/IIIa blockade in patients undergoing coronary stenting: results from a multicentre randomised trial. EPISTENT Investigators. Evaluation of Platelet IIb/IIIa Inhibitor for Stenting. Lancet. 1999 Dec 11; 354(9195):2019-24. PMID: 10636365.
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    263. Marso SP, Lincoff AM, Ellis SG, Bhatt DL, Tanguay JF, Kleiman NS, Hammoud T, Booth JE, Sapp SK, Topol EJ. Optimizing the percutaneous interventional outcomes for patients with diabetes mellitus: results of the EPISTENT (Evaluation of platelet IIb/IIIa inhibitor for stenting trial) diabetic substudy. Circulation. 1999 Dec 21-28; 100(25):2477-84. PMID: 10604884.
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    264. Kleiman NS. Pharmacokinetics and pharmacodynamics of glycoprotein IIb-IIIa inhibitors. Am Heart J. 1999 Oct; 138(4 Pt 2):263-75. PMID: 10502232.
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    265. Miller JM, Smalling R, Ohman EM, Bode C, Betriu A, Kleiman NS, Schildcrout JS, Bastos E, Topol EJ, Califf RM. Effectiveness of early coronary angioplasty and abciximab for failed thrombolysis (reteplase or alteplase) during acute myocardial infarction (results from the GUSTO-III trial). Global Use of Strategies To Open occluded coronary arteries. Am J Cardiol. 1999 Oct 1; 84(7):779-84. PMID: 10513773.
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    266. Lincoff AM, Califf RM, Moliterno DJ, Ellis SG, Ducas J, Kramer JH, Kleiman NS, Cohen EA, Booth JE, Sapp SK, Cabot CF, Topol EJ. Complementary clinical benefits of coronary-artery stenting and blockade of platelet glycoprotein IIb/IIIa receptors. Evaluation of Platelet IIb/IIIa Inhibition in Stenting Investigators. N Engl J Med. 1999 Jul 29; 341(5):319-27. PMID: 10423466.
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    267. Scarborough RM, Kleiman NS, Phillips DR. Platelet glycoprotein IIb/IIIa antagonists. What are the relevant issues concerning their pharmacology and clinical use? Circulation. 1999 Jul 27; 100(4):437-44. PMID: 10421606.
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    268. McClure MW, Berkowitz SD, Sparapani R, Tuttle R, Kleiman NS, Berdan LG, Lincoff AM, Deckers J, Diaz R, Karsch KR, Gretler D, Kitt M, Simoons M, Topol EJ, Califf RM, Harrington RA. Clinical significance of thrombocytopenia during a non-ST-elevation acute coronary syndrome. The platelet glycoprotein IIb/IIIa in unstable angina: receptor suppression using integrilin therapy (PURSUIT) trial experience. Circulation. 1999 Jun 8; 99(22):2892-900. PMID: 10359733.
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    269. Antman EM, Giugliano RP, Gibson CM, McCabe CH, Coussement P, Kleiman NS, Vahanian A, Adgey AA, Menown I, Rupprecht HJ, Van der Wieken R, Ducas J, Scherer J, Anderson K, Van de Werf F, Braunwald E. Abciximab facilitates the rate and extent of thrombolysis: results of the thrombolysis in myocardial infarction (TIMI) 14 trial. The TIMI 14 Investigators. Circulation. 1999 Jun 1; 99(21):2720-32. PMID: 10351964.
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    270. Kleiman NS. GP IIb/IIIa antagonists. Clinical experience and potential uses in cardiology. Drugs R D. 1999 May; 1(5):361-70. PMID: 10566065.
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    271. Mazur W, Kaluza G, Kleiman NS. Antiplatelet therapy for treatment of acute coronary syndromes. Cardiol Clin. 1999 May; 17(2):345-57, ix. PMID: 10384831.
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    272. Lincoff AM, Tcheng JE, Califf RM, Kereiakes DJ, Kelly TA, Timmis GC, Kleiman NS, Booth JE, Balog C, Cabot CF, Anderson KM, Weisman HF, Topol EJ. Sustained suppression of ischemic complications of coronary intervention by platelet GP IIb/IIIa blockade with abciximab: one-year outcome in the EPILOG trial. Evaluation in PTCA to Improve Long-term Outcome with abciximab GP IIb/IIIa blockade. Circulation. 1999 Apr 20; 99(15):1951-8. PMID: 10208997.
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    273. Kleiman NS. Much ado about thrombin. Am Heart J. 1999 Feb; 137(2):196-8. PMID: 9924148.
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    274. Kleiman NS. A risk-benefit assessment of abciximab in angioplasty. Drug Saf. 1999 Jan; 20(1):43-57. PMID: 9935276.
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    275. Kleiman NS, Granger CB, White HD, Armstrong P, Ardissino D, de Werf FV, Zoldeyhi P, Thompson TD, Califf RM, Topol EJ. Death and nonfatal reinfarction within the first 24 hours after presentation with an acute coronary syndrome: experience from GUSTO-IIb. Global Utilization of Strategies for Total Occlusion. Am Heart J. 1999 Jan; 137(1):12-23. PMID: 9878932.
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    276. Mickelson JK, Ali MN, Kleiman NS, Lakkis NM, Chow TW, Hughes BJ, Smith CW. Chimeric 7E3 Fab (ReoPro) decreases detectable CD11b on neutrophils from patients undergoing coronary angioplasty. J Am Coll Cardiol. 1999 Jan; 33(1):97-106. PMID: 9935015.
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    277. Ellis SG, Lincoff AM, Miller D, Tcheng JE, Kleiman NS, Kereiakes D, Califf R, Topol EJ. Reduction in complications of angioplasty with abciximab occurs largely independently of baseline lesion morphology. EPIC and EPILOG Investigators. Evaluation of 7E3 for the Prevention of Ischemic Complications. Evaluation of PTCA To Improve Long-term Outcome with abciximab GPIIb/IIIa Receptor Blockade. J Am Coll Cardiol. 1998 Nov 15; 32(6):1619-23. PMID: 9822087.
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    278. Dakik HA, Kleiman NS, Farmer JA, He ZX, Wendt JA, Pratt CM, Verani MS, Mahmarian JJ. Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study. Circulation. 1998 Nov 10; 98(19):2017-23. PMID: 9808599.
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    279. Lakkis NM, Nagueh SF, Kleiman NS, Killip D, He ZX, Verani MS, Roberts R, Spencer WH. Echocardiography-guided ethanol septal reduction for hypertrophic obstructive cardiomyopathy. Circulation. 1998 Oct 27; 98(17):1750-5. PMID: 9788829.
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    280. Ramanathan A, Kleiman NS. Glycoprotein IIb-IIIa antagonists in percutaneous coronary interventions and acute coronary syndromes. Indian Heart J. 1998 Oct; 50 Suppl 1:45-56. PMID: 9824907.
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    281. Harrington RA, Kleiman NS, Granger CB, Ohman EM, Berkowitz SD. Relation between inhibition of platelet aggregation and clinical outcomes. Am Heart J. 1998 Oct; 136(4 Pt 2 Su):S43-50. PMID: 9778087.
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    282. Kleiman NS, Lincoff AM, Ohman EM, Harrington RA. Glycoprotein IIb/IIIa inhibitors in acute coronary syndromes: pathophysiologic foundation and clinical findings. Am Heart J. 1998 Oct; 136(4 Pt 2 Su):S32-42. PMID: 9778086.
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    283. Kereiakes DJ, Kleiman NS, Ferguson JJ, Masud AR, Broderick TM, Abbottsmith CW, Runyon JP, Anderson LC, Anders RJ, Dreiling RJ, Hantsbarger GL, Bryzinski B, Topol EJ. Pharmacodynamic efficacy, clinical safety, and outcomes after prolonged platelet Glycoprotein IIb/IIIa receptor blockade with oral xemilofiban: results of a multicenter, placebo-controlled, randomized trial. Circulation. 1998 Sep 29; 98(13):1268-78. PMID: 9751674.
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    284. Mazur W, Bitar JN, Young JB, Khalil AA, Vardan S, Short BC, Rivera JM, Raizner AE, Farmer JA, Zoghbi WA, Kleiman NS. Progressive deterioration of coronary flow reserve after heart transplantation. Am Heart J. 1998 Sep; 136(3):504-9. PMID: 9736145.
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    285. Mazur W, Bitar JN, Lechin M, Grinstead WC, Khalil AA, Khan MM, Sekili S, Zoghbi WA, Raizner AE, Kleiman NS. Coronary flow reserve may predict myocardial recovery after myocardial infarction in patients with TIMI grade 3 flow. Am Heart J. 1998 Aug; 136(2):335-44. PMID: 9704699.
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    286. Ghaffari S, Kereiakes DJ, Lincoff AM, Kelly TA, Timmis GC, Kleiman NS, Ferguson JJ, Miller DP, Califf RA, Topol EJ. Platelet glycoprotein IIb/IIIa receptor blockade with abciximab reduces ischemic complications in patients undergoing directional coronary atherectomy. EPILOG Investigators. Evaluation of PTCA to Improve Long-term Outcome by c7E3 GP IIb/IIIa Receptor Blockade. Am J Cardiol. 1998 Jul 1; 82(1):7-12. PMID: 9671000.
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    287. Nagueh SF, Lakkis NM, He ZX, Middleton KJ, Killip D, Zoghbi WA, Quiñones MA, Roberts R, Verani MS, Kleiman NS, Spencer WH. Role of myocardial contrast echocardiography during nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy. J Am Coll Cardiol. 1998 Jul; 32(1):225-9. PMID: 9669274.
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    288. Dakik HA, Farmer J, Kleiman NS. Images in cardiovascular medicine. Fistula between left main, left anterior descending, and pulmonary arteries. Circulation. 1998 May 26; 97(20):2091-2. PMID: 9610541.
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    289. Kleiman NS, Lincoff AM, Kereiakes DJ, Miller DP, Aguirre FV, Anderson KM, Weisman HF, Califf RM, Topol EJ. Diabetes mellitus, glycoprotein IIb/IIIa blockade, and heparin: evidence for a complex interaction in a multicenter trial. EPILOG Investigators. Circulation. 1998 May 19; 97(19):1912-20. PMID: 9609084.
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    290. Califf RM, Abdelmeguid AE, Kuntz RE, Popma JJ, Davidson CJ, Cohen EA, Kleiman NS, Mahaffey KW, Topol EJ, Pepine CJ, Lipicky RJ, Granger CB, Harrington RA, Tardiff BE, Crenshaw BS, Bauman RP, Zuckerman BD, Chaitman BR, Bittl JA, Ohman EM. Myonecrosis after revascularization procedures. J Am Coll Cardiol. 1998 Feb; 31(2):241-51. PMID: 9462562.
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    291. Brieger DB, Mak KH, White HD, Kleiman NS, Miller DP, Vahanian A, Ross AM, Califf RM, Topol EJ. Benefit of early sustained reperfusion in patients with prior myocardial infarction (the GUSTO-I trial). Global Utilization of Streptokinase and TPA for occluded arteries. Am J Cardiol. 1998 Feb 1; 81(3):282-7. PMID: 9468068.
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    292. Tracy RP, Kleiman NS, Thompson B, Cannon CP, Bovill EG, Brown RG, Collen D, Mahan E, Mann KG, Rogers WJ, Sopko G, Stump DC, Williams DO, Zaret BL. Relation of coagulation parameters to patency and recurrent ischemia in the Thrombolysis in Myocardial Infarction (TIMI) Phase II Trial. Am Heart J. 1998 Jan; 135(1):29-37. PMID: 9453518.
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    293. Khan MM, Ellis SG, Aguirre FV, Weisman HF, Wildermann NM, Califf RM, Topol EJ, Kleiman NS. Does intracoronary thrombus influence the outcome of high risk percutaneous transluminal coronary angioplasty? Clinical and angiographic outcomes in a large multicenter trial. EPIC Investigators. Evaluation of IIb/IIIa Platelet Receptor Antagonist 7E3 in Preventing Ischemic Complications. J Am Coll Cardiol. 1998 Jan; 31(1):31-6. PMID: 9426014.
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    294. Kleiman NS. Pharmacology of the intravenous platelet receptor glycoprotein IIb-IIIa antagonists. Coron Artery Dis. 1998; 9(9):603-16. PMID: 9861523.
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    295. Kereiakes DJ, Kleiman N, Ferguson JJ, Runyon JP, Broderick TM, Higby NA, Martin LH, Hantsbarger G, McDonald S, Anders RJ. Sustained platelet glycoprotein IIb/IIIa blockade with oral xemilofiban in 170 patients after coronary stent deployment. Circulation. 1997 Aug 19; 96(4):1117-21. PMID: 9286938.
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    296. Kleiman NS. Primary and secondary safety endpoints from IMPACT II. Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis. Am J Cardiol. 1997 Aug 18; 80(4A):29B-33B. PMID: 9291243.
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    297. Topol EJ, Ferguson JJ, Weisman HF, Tcheng JE, Ellis SG, Kleiman NS, Ivanhoe RJ, Wang AL, Miller DP, Anderson KM, Califf RM. Long-term protection from myocardial ischemic events in a randomized trial of brief integrin beta3 blockade with percutaneous coronary intervention. EPIC Investigator Group. Evaluation of Platelet IIb/IIIa Inhibition for Prevention of Ischemic Complication. JAMA. 1997 Aug 13; 278(6):479-84. PMID: 9256222.
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    298. Levine G, Khan MM, Kleiman NS, Raizner AE, Jeroudi MO, Mickelson J, Ali MN. Use of bare-mounted Palmaz-Schatz stents employing the stent saddle technique on the delivery balloon: a single center experience. Cathet Cardiovasc Diagn. 1997 Aug; 41(4):361-8. PMID: 9258473.
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    299. Lincoff AM, Califf RM, Anderson KM, Weisman HF, Aguirre FV, Kleiman NS, Harrington RA, Topol EJ. Evidence for prevention of death and myocardial infarction with platelet membrane glycoprotein IIb/IIIa receptor blockade by abciximab (c7E3 Fab) among patients with unstable angina undergoing percutaneous coronary revascularization. EPIC Investigators. Evaluation of 7E3 in Preventing Ischemic Complications. J Am Coll Cardiol. 1997 Jul; 30(1):149-56. PMID: 9207636.
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    300. Lakkis N, Kleiman N, Killip D, Spencer WH. Hypertrophic obstructive cardiomyopathy: alternative therapeutic options. Clin Cardiol. 1997 May; 20(5):417-8. PMID: 9134270.
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    301. Ohman EM, Kleiman NS, Gacioch G, Worley SJ, Navetta FI, Talley JD, Anderson HV, Ellis SG, Cohen MD, Spriggs D, Miller M, Kereiakes D, Yakubov S, Kitt MM, Sigmon KN, Califf RM, Krucoff MW, Topol EJ. Combined accelerated tissue-plasminogen activator and platelet glycoprotein IIb/IIIa integrin receptor blockade with Integrilin in acute myocardial infarction. Results of a randomized, placebo-controlled, dose-ranging trial. IMPACT-AMI Investigators. Circulation. 1997 Feb 18; 95(4):846-54. PMID: 9054741.
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    302. Bovill EG, Tracy RP, Knatterud GL, Stone PH, Nasmith J, Gore JM, Thompson BW, Tofler GH, Kleiman NS, Cannon C, Braunwald E. Hemorrhagic events during therapy with recombinant tissue plasminogen activator, heparin, and aspirin for unstable angina (Thrombolysis in Myocardial Ischemia, phase IIIB trial). Am J Cardiol. 1997 Feb 15; 79(4):391-6. PMID: 9052337.
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    303. Kamat SG, Turner NA, Konstantopoulos K, Hellums JD, McIntire LV, Kleiman NS, Moake JL. Effects of Integrelin on platelet function in flow models of arterial thrombosis. J Cardiovasc Pharmacol. 1997 Feb; 29(2):156-63. PMID: 9057063.
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    304. Lincoff AM, Tcheng JE, Califf RM, Bass T, Popma JJ, Teirstein PS, Kleiman NS, Hattel LJ, Anderson HV, Ferguson JJ, Cabot CF, Anderson KM, Berdan LG, Musco MH, Weisman HF, Topol EJ. Standard versus low-dose weight-adjusted heparin in patients treated with the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3 Fab) during percutaneous coronary revascularization. PROLOG Investigators. Am J Cardiol. 1997 Feb 1; 79(3):286-91. PMID: 9036746.
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    305. Cannon CP, McCabe CH, Stone PH, Schactman M, Thompson B, Theroux P, Gibson RS, Feldman T, Kleiman NS, Tofler GH, Muller JE, Chaitman BR, Braunwald E. Circadian variation in the onset of unstable angina and non-Q-wave acute myocardial infarction (the TIMI III Registry and TIMI IIIB). Am J Cardiol. 1997 Feb 1; 79(3):253-8. PMID: 9036740.
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    306. Espada R, Talwalker NG, Wilcox G, Kleiman NS, Verani MS. Visualization of ventricular fibroelastoma with a video-assisted thoracoscope. Ann Thorac Surg. 1997 Jan; 63(1):221-3. PMID: 8993270.
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    307. Labinaz M, Sketch MH, Stebbins AL, DeFranco AC, Holmes DR, Kleiman NS, Betriu A, Rutsch WR, Vahanian A, Topol EJ, Califf RM. Thrombolytic therapy for patients with prior percutaneous transluminal coronary angioplasty and subsequent acute myocardial infarction. GUSTO-I Investigators. Global Utilization of Streptokinase and t-PA for Occluded Coronary Arteries. Am J Cardiol. 1996 Dec 15; 78(12):1338-44. PMID: 8970403.
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    308. Ali MN, Mazur W, Kleiman NS, Rodgers GP, Abukhalil JM, French BA, Raizner AE. Inhibition of coronary restenosis by antithrombin III in atherosclerotic swine. Coron Artery Dis. 1996 Nov; 7(11):851-61. PMID: 8993944.
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    309. Ohman EM, Armstrong PW, Christenson RH, Granger CB, Katus HA, Hamm CW, O'Hanesian MA, Wagner GS, Kleiman NS, Harrell FE, Califf RM, Topol EJ. Cardiac troponin T levels for risk stratification in acute myocardial ischemia. GUSTO IIA Investigators. N Engl J Med. 1996 Oct 31; 335(18):1333-41. PMID: 8857016.
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    310. White HD, Barbash GI, Califf RM, Simes RJ, Granger CB, Weaver WD, Kleiman NS, Aylward PE, Gore JM, Vahanian A, Lee KL, Ross AM, Topol EJ. Age and outcome with contemporary thrombolytic therapy. Results from the GUSTO-I trial. Global Utilization of Streptokinase and TPA for Occluded coronary arteries trial. Circulation. 1996 Oct 15; 94(8):1826-33. PMID: 8873656.
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    311. Marian AJ, Brugada R, Kleiman NS. Platelet glycoprotein IIIa PlA polymorphism and myocardial infarction. N Engl J Med. 1996 Oct 3; 335(14):1071-2; author reply 1073-4. PMID: 8801456.
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    312. Kereiakes DJ, Runyon JP, Kleiman NS, Higby NA, Anderson LC, Hantsbarger G, McDonald S, Anders RJ. Differential dose-response to oral xemilofiban after antecedent intravenous abciximab. Administration for complex coronary intervention. Circulation. 1996 Sep 1; 94(5):906-10. PMID: 8790024.
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    313. Kleiman NS. Clinical trials of conjunctive anticoagulant strategies in thrombolysis. Coron Artery Dis. 1996 Jul; 7(7):508-15. PMID: 8913678.
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    314. Stone PH, Thompson B, Anderson HV, Kronenberg MW, Gibson RS, Rogers WJ, Diver DJ, Théroux P, Warnica JW, Nasmith JB, Kells C, Kleiman N, McCabe CH, Schactman M, Knatterud GL, Braunwald E. Influence of race, sex, and age on management of unstable angina and non-Q-wave myocardial infarction: The TIMI III registry. JAMA. 1996 Apr 10; 275(14):1104-12. PMID: 8601930.
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    315. Kereiakes DJ, Kleiman NS, Ambrose J, Cohen M, Rodriguez S, Palabrica T, Herrmann HC, Sutton JM, Weaver WD, McKee DB, Fitzpatrick V, Sax FL. Randomized, double-blind, placebo-controlled dose-ranging study of tirofiban (MK-383) platelet IIb/IIIa blockade in high risk patients undergoing coronary angioplasty. J Am Coll Cardiol. 1996 Mar 1; 27(3):536-42. PMID: 8606262.
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    316. Kleiman NS, Anderson HV, Rogers WJ, Theroux P, Thompson B, Stone PH. Comparison of outcome of patients with unstable angina and non-Q-wave acute myocardial infarction with and without prior coronary artery bypass grafting (Thrombolysis in Myocardial Ischemia III Registry). Am J Cardiol. 1996 Feb 1; 77(4):227-31. PMID: 8607398.
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    317. Tawa CB, Baker WB, Kleiman NS, Trakhtenbroit A, Desir R, Zoghbi WA. Comparison of adenosine echocardiography, with and without isometric handgrip, to exercise echocardiography in the detection of ischemia in patients with coronary artery disease. J Am Soc Echocardiogr. 1996 Jan-Feb; 9(1):33-43. PMID: 8679235.
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    318. Harrington RA, Kleiman NS, Kottke-Marchant K, Lincoff AM, Tcheng JE, Sigmon KN, Joseph D, Rios G, Trainor K, Rose D, et al. Immediate and reversible platelet inhibition after intravenous administration of a peptide glycoprotein IIb/IIIa inhibitor during percutaneous coronary intervention. Am J Cardiol. 1995 Dec 15; 76(17):1222-7. PMID: 7503000.
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    319. Kleiman NS, Raizner AE, Jordan R, Wang AL, Norton D, Mace KF, Joshi A, Coller BS, Weisman HF. Differential inhibition of platelet aggregation induced by adenosine diphosphate or a thrombin receptor-activating peptide in patients treated with bolus chimeric 7E3 Fab: implications for inhibition of the internal pool of GPIIb/IIIa receptors. J Am Coll Cardiol. 1995 Dec; 26(7):1665-71. PMID: 7594101.
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    320. Kleiman NS. Description of patients undergoing high risk angioplasty. Analyses of various databases. Eur Heart J. 1995 Nov; 16 Suppl L:30-5. PMID: 8869016.
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    321. Ohman EM, Harrington RA, Lincoff AM, Kitt MM, Kleiman NS, Tcheng JE. Early clinical experience with integrelin, an inhibitor of the platelet glycoprotein IIb/IIIa integrin receptor. Eur Heart J. 1995 Nov; 16 Suppl L:50-5. PMID: 8869019.
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    322. Holmes DR, Bates ER, Kleiman NS, Sadowski Z, Horgan JH, Morris DC, Califf RM, Berger PB, Topol EJ. Contemporary reperfusion therapy for cardiogenic shock: the GUSTO-I trial experience. The GUSTO-I Investigators. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. J Am Coll Cardiol. 1995 Sep; 26(3):668-74. PMID: 7642857.
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    323. Kamat SG, Kleiman NS. Platelets and platelet inhibitors in acute myocardial infarction. Cardiol Clin. 1995 Aug; 13(3):435-47. PMID: 7585778.
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    324. Halle AA, DiSciascio G, Massin EK, Wilson RF, Johnson MR, Sullivan HJ, Bourge RC, Kleiman NS, Miller LW, Aversano TR, et al. Coronary angioplasty, atherectomy and bypass surgery in cardiac transplant recipients. J Am Coll Cardiol. 1995 Jul; 26(1):120-8. PMID: 7797740.
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    325. Beohar N, Damaraju S, Prather A, Yu QT, Raizner A, Kleiman NS, Roberts R, Marian AJ. Angiotensin-I converting enzyme genotype DD is a risk factor for coronary artery disease. J Investig Med. 1995 Jun; 43(3):275-80. PMID: 7614074.
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    326. Tcheng JE, Harrington RA, Kottke-Marchant K, Kleiman NS, Ellis SG, Kereiakes DJ, Mick MJ, Navetta FI, Smith JE, Worley SJ, et al. Multicenter, randomized, double-blind, placebo-controlled trial of the platelet integrin glycoprotein IIb/IIIa blocker Integrelin in elective coronary intervention. IMPACT Investigators. Circulation. 1995 Apr 15; 91(8):2151-7. PMID: 7697843.
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    327. Sloan MA, Price TR, Petito CK, Randall AM, Solomon RE, Terrin ML, Gore J, Collen D, Kleiman N, Feit F, et al. Clinical features and pathogenesis of intracerebral hemorrhage after rt-PA and heparin therapy for acute myocardial infarction: the Thrombolysis in Myocardial Infarction (TIMI) II Pilot and Randomized Clinical Trial combined experience. Neurology. 1995 Apr; 45(4):649-58. PMID: 7723950.
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    328. Turner NA, Moake JL, Kamat SG, Schafer AI, Kleiman NS, Jordan R, McIntire LV. Comparative real-time effects on platelet adhesion and aggregation under flowing conditions of in vivo aspirin, heparin, and monoclonal antibody fragment against glycoprotein IIb-IIIa. Circulation. 1995 Mar 1; 91(5):1354-62. PMID: 7867173.
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    329. Konstantopoulos K, Kamat SG, Schafer AI, Bañez EI, Jordan R, Kleiman NS, Hellums JD. Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty. Circulation. 1995 Mar 1; 91(5):1427-31. PMID: 7867183.
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    330. Afridi I, Kleiman NS, Raizner AE, Zoghbi WA. Dobutamine echocardiography in myocardial hibernation. Optimal dose and accuracy in predicting recovery of ventricular function after coronary angioplasty. Circulation. 1995 Feb 1; 91(3):663-70. PMID: 7828291.
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    331. Kleiman NS, White HD, Ohman EM, Ross AM, Woodlief LH, Califf RM, Holmes DR, Bates E, Pfisterer M, Vahanian A, et al. Mortality within 24 hours of thrombolysis for myocardial infarction. The importance of early reperfusion. The GUSTO Investigators, Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries. Circulation. 1994 Dec; 90(6):2658-65. PMID: 7994805.
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    332. Tcheng JE, Ellis SG, George BS, Kereiakes DJ, Kleiman NS, Talley JD, Wang AL, Weisman HF, Califf RM, Topol EJ. Pharmacodynamics of chimeric glycoprotein IIb/IIIa integrin antiplatelet antibody Fab 7E3 in high-risk coronary angioplasty. Circulation. 1994 Oct; 90(4):1757-64. PMID: 7923659.
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    333. Dabaghi SF, Kamat SG, Payne J, Marks GF, Roberts R, Schafer AI, Kleiman NS. Effects of low-dose aspirin on in vitro platelet aggregation in the early minutes after ingestion in normal subjects. Am J Cardiol. 1994 Oct 1; 74(7):720-3. PMID: 7942533.
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    334. Aguirre FV, McMahon RP, Mueller H, Kleiman NS, Kern MJ, Desvigne-Nickens P, Hamilton WP, Chaitman BR. Impact of age on clinical outcome and postlytic management strategies in patients treated with intravenous thrombolytic therapy. Results from the TIMI II Study. TIMI II Investigators. Circulation. 1994 Jul; 90(1):78-86. PMID: 8026055.
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    335. Lowry RW, Bitar JN, Grinstead WC, Young JB, Noon GP, Vardan S, Cocanougher B, Kleiman NS. Heterotopic heart transplantation: catheterization, endomyocardial biopsy, and coronary angiography of the donor heart. Cathet Cardiovasc Diagn. 1994 May; 32(1):18-26. PMID: 8039213.
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    336. Topol EJ, Fuster V, Harrington RA, Califf RM, Kleiman NS, Kereiakes DJ, Cohen M, Chapekis A, Gold HK, Tannenbaum MA, et al. Recombinant hirudin for unstable angina pectoris. A multicenter, randomized angiographic trial. Circulation. 1994 Apr; 89(4):1557-66. PMID: 8149521.
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    337. Cannon CP, McCabe CH, Henry TD, Schweiger MJ, Gibson RS, Mueller HS, Becker RC, Kleiman NS, Haugland JM, Anderson JL, et al. A pilot trial of recombinant desulfatohirudin compared with heparin in conjunction with tissue-type plasminogen activator and aspirin for acute myocardial infarction: results of the Thrombolysis in Myocardial Infarction (TIMI) 5 trial. J Am Coll Cardiol. 1994 Apr; 23(5):993-1003. PMID: 8144799.
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    338. Kleiman NS, Tracy RP, Schaaff LJ, Harris S, Hill RD, Puleo P, Roberts R. Prostaglandin E1 does not accelerate rTPA-induced thrombolysis in acute myocardial infarction. Am Heart J. 1994 Apr; 127(4 Pt 1):738-43. PMID: 8154410.
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    339. Roberts R, Kleiman NS. Earlier diagnosis and treatment of acute myocardial infarction necessitates the need for a 'new diagnostic mind-set'. Circulation. 1994 Feb; 89(2):872-81. PMID: 8313577.
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    340. Lowry RW, Kleiman NS, Raizner AE, Young JB. Is intravascular ultrasound better than quantitative coronary arteriography to assess cardiac allograft arteriopathy? Cathet Cardiovasc Diagn. 1994 Feb; 31(2):110-5. PMID: 8149421.
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    341. Lowry RW, Adam E, Hu C, Kleiman NS, Cocanougher B, Windsor N, Bitar JN, Melnick JL, Young JB. What are the implications of cardiac infection with cytomegalovirus before heart transplantation? J Heart Lung Transplant. 1994 Jan-Feb; 13(1 Pt 1):122-8. PMID: 8167117.
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    342. Terrin ML, Williams DO, Kleiman NS, Willerson J, Mueller HS, Desvigne-Nickens P, Forman SA, Knatterud GL, Braunwald E. Two- and three-year results of the Thrombolysis in Myocardial Infarction (TIMI) Phase II clinical trial. J Am Coll Cardiol. 1993 Dec; 22(7):1763-72. PMID: 8245326.
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    343. Bernardi MM, Califf RM, Kleiman N, Ellis SG, Topol EJ. Lack of usefulness of prolonged bleeding times in predicting hemorrhagic events in patients receiving the 7E3 glycoprotein IIb/IIIa platelet antibody. The TAMI Study Group. Am J Cardiol. 1993 Nov 15; 72(15):1121-5. PMID: 8237799.
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    344. Kleiman NS, Ohman EM, Califf RM, George BS, Kereiakes D, Aguirre FV, Weisman H, Schaible T, Topol EJ. Profound inhibition of platelet aggregation with monoclonal antibody 7E3 Fab after thrombolytic therapy. Results of the Thrombolysis and Angioplasty in Myocardial Infarction (TAMI) 8 Pilot Study. J Am Coll Cardiol. 1993 Aug; 22(2):381-9. PMID: 8335808.
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    345. Lowry RW, Young JB, Kleiman NS, Zoghbi WA. Transesophageal echocardiographic demonstration of right coronary artery-to-coronary sinus fistula in a heart transplant recipient. J Am Soc Echocardiogr. 1993 Jul-Aug; 6(4):449-52. PMID: 8217212.
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    346. Smart FW, Young JB, Weilbaecher D, Kleiman NS, Wendt RE, Johnston DL. Magnetic resonance imaging for assessment of tissue rejection after heterotopic heart transplantation. J Heart Lung Transplant. 1993 May-Jun; 12(3):403-10. PMID: 8329410.
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    347. Cocanougher B, Ballantyne CM, Pollack MS, Payton-Ross C, Lowry R, Kleiman NS, Farmer JA, Noon GP, Short HD, Young JB. Degree of HLA mismatch as a predictor of death from allograft arteriopathy after heart transplant. Transplant Proc. 1993 Feb; 25(1 Pt 1):233-6. PMID: 8438282.
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    348. Brandao JJ, Brademan GM, Moore CE, Wright D, Kleiman NS. Effectiveness of videotaped dietary instruction for patients hospitalized with cardiovascular disease. J Am Diet Assoc. 1992 Oct; 92(10):1268-70. PMID: 1401668.
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    349. Hsia J, Kleiman N, Aguirre F, Chaitman BR, Roberts R, Ross AM. Heparin-induced prolongation of partial thromboplastin time after thrombolysis: relation to coronary artery patency. HART Investigators. J Am Coll Cardiol. 1992 Jul; 20(1):31-5. PMID: 1607535.
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    350. Mulvagh S, Quiñones MA, Kleiman NS, Cheirif J, Zoghbi WA. Estimation of left ventricular end-diastolic pressure from Doppler transmitral flow velocity in cardiac patients independent of systolic performance. J Am Coll Cardiol. 1992 Jul; 20(1):112-9. PMID: 1607511.
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    351. Zacca NM, Kleiman NS, Rodriguez AR, Heibig J, Warth D, Harris S, Minor ST, Raizner AE. Rotational ablation of coronary artery lesions using single, large burrs. Cathet Cardiovasc Diagn. 1992 Jun; 26(2):92-7. PMID: 1606609.
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    352. Topol EJ, Armstrong P, Van de Werf F, Kleiman N, Lee K, Morris D, Simoons M, Barbash G, White H, Califf RM. Confronting the issues of patient safety and investigator conflict of interest in an international clinical trial of myocardial reperfusion. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries (GUSTO) Steering Committee. J Am Coll Cardiol. 1992 May; 19(6):1123-8. PMID: 1564212.
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    353. Young JB, Windsor NT, Kleiman NS, Lowry R, Cocanougher B, Lawrence EC. The relationship of soluble interleukin-2 receptor levels to allograft arteriopathy after heart transplantation. J Heart Lung Transplant. 1992 May-Jun; 11(3 Pt 2):S79-82. PMID: 1623006.
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    354. Kleiman NS, Terrin M, Mueller H, Chaitman B, Roberts R, Knatterud GL, Solomon R, McMahon RP, Braunwald E. Mechanisms of early death despite thrombolytic therapy: experience from the Thrombolysis in Myocardial Infarction Phase II (TIMI II) study. J Am Coll Cardiol. 1992 May; 19(6):1129-35. PMID: 1348750.
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    355. Young JB, Smart FM, Lowry RL, Kleiman NS. Coronary angiography after heart transplantation: should perioperative study be the "gold standard"? J Heart Lung Transplant. 1992 May-Jun; 11(3 Pt 2):S65-8. PMID: 1623003.
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    356. Kleiman NS, Rodriguez AR, Raizner AE. Interobserver variability in grading of coronary arterial narrowings using the American College of Cardiology/American Heart Association grading criteria. Am J Cardiol. 1992 Feb 1; 69(4):413-5. PMID: 1734658.
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    357. Kleiman NS. Goals of thrombolytic therapy. Am J Cardiol. 1991 Nov 4; 68(12):67C-71C. PMID: 1951108.
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    358. Zoghbi WA, Cheirif J, Kleiman NS, Verani MS, Trakhtenbroit A. Diagnosis of ischemic heart disease with adenosine echocardiography. J Am Coll Cardiol. 1991 Nov 1; 18(5):1271-9. PMID: 1918704.
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    359. Young JB, Windsor NT, Smart FW, Kleiman NS, Weilbaecher DG, Noon GP, Nelson DL, Lawrence EC. Inability of isolated soluble interleukin-2 receptor levels to predict biopsy rejection scores after heart transplantation. Transplantation. 1991 Mar; 51(3):636-41. PMID: 2006520.
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    360. Marzoll U, Kleiman NS, Dunn JK, Verani MS, Minor ST, Roberts R, Raizner AE. Factors determining improvement in left ventricular function after reperfusion therapy for acute myocardial infarction: primacy of baseline ejection fraction. J Am Coll Cardiol. 1991 Mar 1; 17(3):613-20. PMID: 1993777.
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    361. Young JB, Lloyd KS, Windsor NT, Cocanougher B, Weilbaecher DG, Kleiman NS, Smart FW, Nelson DL, Lawrence EC. Elevated soluble interleukin-2 receptor levels early after heart transplantation and long-term survival and development of coronary arteriopathy. J Heart Lung Transplant. 1991 Mar-Apr; 10(2):243-50. PMID: 2031920.
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    362. Smart FW, Grinstead WC, Cocanougher B, Ballantyne CM, Farmer JA, Kleiman N, Young JB. Detection of transplant arteriopathy: does exercise thallium scintigraphy improve noninvasive diagnostic capabilities? Transplant Proc. 1991 Feb; 23(1 Pt 2):1189-92. PMID: 1989183.
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    363. Rowe SK, Kleiman NS, Cocanougher B, Smart FW, Minor ST, Raizner AE, Henry PD, Roberts R, Pratt CM, Young JB. Effects of intracoronary acetylcholine infusion early versus late after heart transplant. Transplant Proc. 1991 Feb; 23(1 Pt 2):1193-7. PMID: 1899156.
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    364. Hsia J, Hamilton WP, Kleiman N, Roberts R, Chaitman BR, Ross AM. A comparison between heparin and low-dose aspirin as adjunctive therapy with tissue plasminogen activator for acute myocardial infarction. Heparin-Aspirin Reperfusion Trial (HART) Investigators. N Engl J Med. 1990 Nov 22; 323(21):1433-7. PMID: 2122251.
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    365. Jeroudi MO, Kleiman NS, Minor ST, Hess KR, Lewis JM, Winters WL, Raizner AE. Percutaneous transluminal coronary angioplasty in octogenarians. Ann Intern Med. 1990 Sep 15; 113(6):423-8. PMID: 2386335.
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    366. Kleiman NS, Raizner AE, Roberts R. Percutaneous transluminal coronary angioplasty: is what we see what we get? J Am Coll Cardiol. 1990 Sep; 16(3):576-7. PMID: 2387930.
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    367. Williams DO, Topol EJ, Califf RM, Roberts R, Mancini GB, Joelson JM, Ellis SG, Kleiman NS. Intravenous recombinant tissue-type plasminogen activator in patients with unstable angina pectoris. Results of a placebo-controlled, randomized trial. Circulation. 1990 Aug; 82(2):376-83. PMID: 2115407.
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    368. Rodriguez AR, Kleiman NS, Minor ST, Zoghbi WA, West MS, DeFelice CA, Samuels DA, Cashion R, Pickett JD, Lewis JM, et al. Factors influencing the outcome of balloon aortic valvuloplasty in the elderly. Am Heart J. 1990 Aug; 120(2):373-80. PMID: 2382614.
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    369. Kleiman NS, Schechtman KB, Young PM, Goodman DA, Boden WE, Pratt CM, Roberts R. Lack of diurnal variation in the onset of non-Q wave infarction. Circulation. 1990 Feb; 81(2):548-55. PMID: 1967558.
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    370. Goldberg RK, Kleiman NS, Minor ST, Abukhalil J, Raizner AE. Comparison of quantitative coronary angiography to visual estimates of lesion severity pre and post PTCA. Am Heart J. 1990 Jan; 119(1):178-84. PMID: 2404387.
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    371. Kleiman NS, Berman DA, Gaston WR, Cashion R, Roberts R. Early intravenous thrombolytic therapy for acute myocardial infarction in patients with prior coronary artery bypass grafts. Am J Cardiol. 1989 Jan 1; 63(1):102-4. PMID: 2491770.
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    372. Rodgers G, Ruplinger J, Spencer W, Cronin L, Kleiman N, Nelson J, Roberts R, Pratt C. Helicopter transport of patients with acute myocardial infarction. Tex Med. 1988 Oct; 84(10):35-7. PMID: 3232109.
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    373. Kleiman N, Roberts R, Pratt C. Thrombolytic treatment for acute myocardial infarction. Tex Med. 1988 Oct; 84(10):27-32. PMID: 3148205.
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    374. Seals AA, Pratt CM, Mahmarian JJ, Tadros S, Kleiman N, Roberts R, Verani MS. Relation of left ventricular dilation during acute myocardial infarction to systolic performance, diastolic dysfunction, infarct size and location. Am J Cardiol. 1988 Feb 1; 61(4):224-9. PMID: 3341198.
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    375. Karim AH, Bennett W, Silver SJ, Kleiman NS, Goodman D, Heibig J. Arteriographic demonstration of coronary artery spasm during thrombolysis. Tex Heart Inst J. 1988; 15(1):52-4. PMID: 15227280; PMCID: PMC324785.
    376. Kleiman NS, Verani MS, George S, Quinones MA, Lawrie GM. Right-to-left intracardiac shunt and constrictive pericarditis following coronary artery bypass surgery. Am Heart J. 1987 Aug; 114(2):431-3. PMID: 3496777.
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    377. Kleiman NS, Lehane DE, Geyer CE, Pratt CM, Young JB. Prinzmetal's angina during 5-fluorouracil chemotherapy. Am J Med. 1987 Mar; 82(3):566-8. PMID: 3826112.
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    378. Jutrin I, Van Dyk D, Lang R, Kleiman N, Shapira J, Ravid M. [Prognostic significance of initial blood glucose levels in acute myocardial infarction]. Harefuah. 1982 Jan 1; 102(1):5-6. PMID: 7095621.
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    379. Ravid M, Kleiman N, Shapira J, Lischner M, Feigl D. Anticoagulant therapy in acute myocardial infarction: demonstration of a selection bias in a retrospective study. Thromb Res. 1980 Jun 15; 18(6):753-7. PMID: 7414562.
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