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MING-JER TSAI

TitleDistinguished Service Professor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleDistinguished Service Professor Emeritus
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Endocrinology


    Collapse Biography 
    Collapse awards and honors
    1968 - 1971Univ. of California Regent's Intern Fellowship , University of california
    1971 - 1973Damon Runyon Memorial postdoctoral fellowship , Damon Runyon
    1995 - 2005MERIT Award on HD-17379 , NICHD
    1996 - preCharles C. Bell Research Professorship , BCM
    1996CaP Cure Research Award , CaP Cure
    1997University of Texas, M.D. Anderson Cancer Center Distinguished Alumnus Award , MD Anderson Cancer Institute
    1999 - 2009MERIT Award on DK45641 , NIH
    2002Michael DeBakey, M.D. Excellence in Research Award , BCM
    2009SCBA-Texas Chapter Achievement Award , SCB Society
    2010 - preDistinguished Service Professor , BCM
    2010 - preAcademician of Academia Sinica , Academia Sinica, Taiwan
    2013SCBA 2013 Lifetime Achievement Award, SCBA society
    2014Endocrine Society 2014 inaugural Outstanding Achievement in Endocrine Science Award, Endocrinology Society
    2014Michael DeBakey, M.D. Excellence in Research Award , Baylor College of Medicine

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
    R01DK062821     (TSAI, MING-JER)Sep 30, 2002 - Jul 31, 2007
    NIH
    Steroid Receptor Coactivators (SRC-3) in Prostate Cancer
    Role: Principal Investigator
    R01DK055325     (TSAI, MING-JER)Sep 30, 1998 - Aug 31, 2004
    NIH
    TRANSCRIP FACTORS IN THE FORMATION OF PANCREATIC ISLETS
    Role: Principal Investigator
    R01DK045641     (TSAI, MING-JER)Sep 30, 1992 - Apr 30, 2018
    NIH
    Mechanism of Action of COUP-Transcription Factors
    Role: Principal Investigator
    R37DK045641     (TSAI, MING-JER)Sep 30, 1992 - Jul 31, 2010
    NIH
    MECHANISM OF ACTION OF COUP TRANSCRIPTION FACTORS
    Role: Principal Investigator
    R01HD017379     (TSAI, MING-JER)Feb 1, 1983 - Jan 31, 2013
    NIH
    In vitro Expression of Hormone Regulated Genes: COUP-TFII in CDH
    Role: Principal Investigator
    R37HD017379     (TSAI, MING-JER)Feb 1, 1983 - Apr 30, 2006
    NIH
    IN VITRO EXPRESSION OF HORMONE-REGULATED GENES
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Wang L, Xu M, Kao CY, Tsai SY, Tsai MJ. Small molecule JQ1 promotes prostate cancer invasion via BET-independent inactivation of FOXA1. J Clin Invest. 2020 04 01; 130(4):1782-1792. PMID: 31874106; PMCID: PMC7108891.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    2. Xu M, Qin J, Wang L, Lee HJ, Kao CY, Liu D, Songyang Z, Chen J, Tsai MJ, Tsai SY. Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019 10; 5(10):eaax6366. PMID: 31633027; PMCID: PMC6785246.
      Citations: 11     Fields:    Translation:HumansCells
    3. Arao Y, Hamilton KJ, Wu SP, Tsai MJ, DeMayo FJ, Korach KS. Dysregulation of hypothalamic-pituitary estrogen receptor a-mediated signaling causes episodic LH secretion and cystic ovary. FASEB J. 2019 06; 33(6):7375-7386. PMID: 30866655; PMCID: PMC6529333.
      Citations: 5     Fields:    Translation:HumansAnimals
    4. Panigrahi AK, Foulds CE, Lanz RB, Hamilton RA, Yi P, Lonard DM, Tsai MJ, Tsai SY, O'Malley BW. SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription. Mol Cell. 2018 05 17; 70(4):679-694.e7. PMID: 29775582; PMCID: PMC5966282.
      Citations: 17     Fields:    Translation:HumansCells
    5. Dasgupta S, Rajapakshe K, Zhu B, Nikolai BC, Yi P, Putluri N, Choi JM, Jung SY, Coarfa C, Westbrook TF, Zhang XH, Foulds CE, Tsai SY, Tsai MJ, O'Malley BW. Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer. Nature. 2018 04; 556(7700):249-254. PMID: 29615789; PMCID: PMC5895503.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    6. Zhao F, Franco HL, Rodriguez KF, Brown PR, Tsai MJ, Tsai SY, Yao HH. Elimination of the male reproductive tract in the female embryo is promoted by COUP-TFII in mice. Science. 2017 08 18; 357(6352):717-720. PMID: 28818950; PMCID: PMC5713893.
      Citations: 28     Fields:    Translation:AnimalsCells
    7. Gates LA, Shi J, Rohira AD, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds CE, O'Malley BW. Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. J Biol Chem. 2017 09 01; 292(35):14456-14472. PMID: 28717009; PMCID: PMC5582839.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    8. Lee HJ, Kao CY, Lin SC, Xu M, Xie X, Tsai SY, Tsai MJ. Dysregulation of nuclear receptor COUP-TFII impairs skeletal muscle development. Sci Rep. 2017 06 09; 7(1):3136. PMID: 28600496; PMCID: PMC5466650.
      Citations: 15     Fields:    Translation:AnimalsCells
    9. Wetendorf M, Wu SP, Wang X, Creighton CJ, Wang T, Lanz RB, Blok L, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment. Biol Reprod. 2017 02 01; 96(2):313-326. PMID: 28203817; PMCID: PMC6225975.
      Citations: 27     Fields:    Translation:AnimalsCells
    10. Xie X, Wu SP, Tsai MJ, Tsai S. The Role of COUP-TFII in Striated Muscle Development and Disease. Curr Top Dev Biol. 2017; 125:375-403. PMID: 28527579.
      Citations: 3     Fields:    Translation:HumansAnimals
    11. Lin SC, Kao CY, Lee HJ, Creighton CJ, Ittmann MM, Tsai SJ, Tsai SY, Tsai MJ. Dysregulation of miRNAs-COUP-TFII-FOXM1-CENPF axis contributes to the metastasis of prostate cancer. Nat Commun. 2016 04 25; 7:11418. PMID: 27108958; PMCID: PMC4848536.
      Citations: 54     Fields:    Translation:HumansAnimals
    12. Vasquez YM, Wu SP, Anderson ML, Hawkins SM, Creighton CJ, Ray M, Tsai SY, Tsai MJ, Lydon JP, DeMayo FJ. Endometrial Expression of Steroidogenic Factor 1 Promotes Cystic Glandular Morphogenesis. Mol Endocrinol. 2016 May; 30(5):518-32. PMID: 27018534; PMCID: PMC4853565.
      Citations: 10     Fields:    Translation:AnimalsCells
    13. Wang L, Xu M, Qin J, Lin SC, Lee HJ, Tsai SY, Tsai MJ. MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer. Oncotarget. 2016 Mar 22; 7(12):14673-83. PMID: 26895100; PMCID: PMC4924743.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    14. Wu SP, Yu CT, Tsai SY, Tsai MJ. Choose your destiny: Make a cell fate decision with COUP-TFII. J Steroid Biochem Mol Biol. 2016 Mar; 157:7-12. PMID: 26658017; PMCID: PMC4724268.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    15. Han SJ, Jung SY, Wu SP, Hawkins SM, Park MJ, Kyo S, Qin J, Lydon JP, Tsai SY, Tsai MJ, DeMayo FJ, O'Malley BW. Estrogen Receptor ? Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis. Cell. 2015 Nov 05; 163(4):960-74. PMID: 26544941; PMCID: PMC4640214.
      Citations: 100     Fields:    Translation:HumansAnimals
    16. Wu SP, Kao CY, Wang L, Creighton CJ, Yang J, Donti TR, Harmancey R, Vasquez HG, Graham BH, Bellen HJ, Taegtmeyer H, Chang CP, Tsai MJ, Tsai SY. Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure. Nat Commun. 2015 Sep 10; 6:8245. PMID: 26356605; PMCID: PMC4568566.
      Citations: 33     Fields:    Translation:AnimalsCells
    17. Kang YK, Putluri N, Maity S, Tsimelzon A, Ilkayeva O, Mo Q, Lonard D, Michailidis G, Sreekumar A, Newgard CB, Wang M, Tsai SY, Tsai MJ, O'Malley BW. CAPER is vital for energy and redox homeostasis by integrating glucose-induced mitochondrial functions via ERR-a-Gabpa and stress-induced adaptive responses via NF-?B-cMYC. PLoS Genet. 2015 Apr; 11(4):e1005116. PMID: 25830341; PMCID: PMC4382186.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    18. Qin J, Lee HJ, Wu SP, Lin SC, Lanz RB, Creighton CJ, DeMayo FJ, Tsai SY, Tsai MJ. Androgen deprivation-induced NCoA2 promotes metastatic and castration-resistant prostate cancer. J Clin Invest. 2014 Nov; 124(11):5013-26. PMID: 25295534; PMCID: PMC4347241.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    19. Xu M, Qin J, Tsai SY, Tsai MJ. The role of the orphan nuclear receptor COUP-TFII in tumorigenesis. Acta Pharmacol Sin. 2015 Jan; 36(1):32-6. PMID: 25283503; PMCID: PMC4571324.
      Citations: 15     Fields:    Translation:HumansAnimals
    20. Qin J, Tsai SY, Tsai MJ. The critical roles of COUP-TFII in tumor progression and metastasis. Cell Biosci. 2014; 4(1):58. PMID: 25328664; PMCID: PMC4201699.
      Citations: 15     
    21. Tang K, Tsai SY, Tsai MJ. COUP-TFs and eye development. Biochim Biophys Acta. 2015 Feb; 1849(2):201-9. PMID: 24878540; PMCID: PMC4246046.
      Citations: 16     Fields:    Translation:HumansAnimals
    22. Gonzaga-Jauregui C, Xu M, de Ligt J, Jhangiani S, Wiszniewski W, Muzny DM, Yntema HG, Pfundt R, Vissers LE, Spruijt L, Blokland EA, Chen CA, Baylor-Hopkins Center for Mendelian Genomics, Lewis RA, Tsai SY, Gibbs RA, Tsai MJ, Lupski JR, Zoghbi HY, Cremers FP, de Vries BB, Schaaf CP, Bosch DG, Boonstra FN. NR2F1 mutations cause optic atrophy with intellectual disability. Am J Hum Genet. 2014 Feb 06; 94(2):303-9. PMID: 24462372; PMCID: PMC3928641.
      Citations: 39     Fields:    Translation:HumansCells
    23. Lin SC, Li YH, Wu MH, Chang YF, Lee DK, Tsai SY, Tsai MJ, Tsai SJ. Suppression of COUP-TFII by proinflammatory cytokines contributes to the pathogenesis of endometriosis. J Clin Endocrinol Metab. 2014 Mar; 99(3):E427-37. PMID: 24423359; PMCID: PMC5393480.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    24. Qin J, Tsai S, Tsai MJ. COUP-TFII, a prognostic marker and therapeutic target for prostate cancer. Asian J Androl. 2013 May; 15(3):360-1. PMID: 23435470; PMCID: PMC3739656.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    25. Qin J, Wu SP, Creighton CJ, Dai F, Xie X, Cheng CM, Frolov A, Ayala G, Lin X, Feng XH, Ittmann MM, Tsai SJ, Tsai MJ, Tsai SY. COUP-TFII inhibits TGF-?-induced growth barrier to promote prostate tumorigenesis. Nature. 2013 Jan 10; 493(7431):236-40. PMID: 23201680; PMCID: PMC4022346.
      Citations: 91     Fields:    Translation:HumansAnimalsCells
    26. Mayer S, Roeser M, Lachmann P, Ishii S, Suh JM, Harlander S, Desch M, Brunssen C, Morawietz H, Tsai SY, Tsai MJ, Hohenstein B, Hugo C, Todorov VT. Chicken ovalbumin upstream promoter transcription factor II regulates renin gene expression. J Biol Chem. 2012 Jul 13; 287(29):24483-91. PMID: 22645148; PMCID: PMC3397873.
      Citations: 7     Fields:    Translation:AnimalsCells
    27. Long W, Foulds CE, Qin J, Liu J, Ding C, Lonard DM, Solis LM, Wistuba II, Tsai SY, Tsai MJ, O'Malley BW. ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion. J Clin Invest. 2012 May; 122(5):1869-80. PMID: 22505454; PMCID: PMC3336992.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    28. Yang Y, Chang BH, Yechoor V, Chen W, Li L, Tsai MJ, Chan L. The Kr?ppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice. Diabetologia. 2011 Oct; 54(10):2595-605. PMID: 21786021; PMCID: PMC3184604.
      Citations: 29     Fields:    Translation:AnimalsCells
    29. Lin FJ, Qin J, Tang K, Tsai SY, Tsai MJ. Coup d'Etat: an orphan takes control. Endocr Rev. 2011 Jun; 32(3):404-21. PMID: 21257780; PMCID: PMC3365794.
      Citations: 80     Fields:    Translation:Animals
    30. Liu J, Yu G, Zhao Y, Zhao D, Wang Y, Wang L, Liu J, Li L, Zeng Y, Dang Y, Wang C, Gao G, Long W, Lonard DM, Qiao S, Tsai MJ, Zhang B, Luo H, Li X. REGgamma modulates p53 activity by regulating its cellular localization. J Cell Sci. 2010 Dec 01; 123(Pt 23):4076-84. PMID: 21084564; PMCID: PMC2987440.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    31. Satoh S, Tang K, Iida A, Inoue M, Kodama T, Tsai SY, Tsai MJ, Furuta Y, Watanabe S. The spatial patterning of mouse cone opsin expression is regulated by bone morphogenetic protein signaling through downstream effector COUP-TF nuclear receptors. J Neurosci. 2009 Oct 07; 29(40):12401-11. PMID: 19812316; PMCID: PMC2791207.
      Citations: 37     Fields:    Translation:AnimalsCells
    32. Kwon IS, Cho SK, Kim MJ, Tsai MJ, Mitsuda N, Suh-Kim H, Lee YD. Expression of Disabled 1 suppresses astroglial differentiation in neural stem cells. Mol Cell Neurosci. 2009 Jan; 40(1):50-61. PMID: 18848628; PMCID: PMC2820303.
      Citations: 6     Fields:    Translation:AnimalsCells
    33. Kruse SW, Suino-Powell K, Zhou XE, Kretschman JE, Reynolds R, Vonrhein C, Xu Y, Wang L, Tsai SY, Tsai MJ, Xu HE. Identification of COUP-TFII orphan nuclear receptor as a retinoic acid-activated receptor. PLoS Biol. 2008 Sep 16; 6(9):e227. PMID: 18798693; PMCID: PMC2535662.
      Citations: 108     Fields:    Translation:HumansAnimalsCells
    34. Neptune ER, Podowski M, Calvi C, Cho JH, Garcia JG, Tuder R, Linnoila RI, Tsai MJ, Dietz HC. Targeted disruption of NeuroD, a proneural basic helix-loop-helix factor, impairs distal lung formation and neuroendocrine morphology in the neonatal lung. J Biol Chem. 2008 Jul 25; 283(30):21160-9. PMID: 18339630; PMCID: PMC2475704.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    35. Faedo A, Tomassy GS, Ruan Y, Teichmann H, Krauss S, Pleasure SJ, Tsai SY, Tsai MJ, Rubenstein JL, Studer M. COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex. 2008 Sep; 18(9):2117-31. PMID: 18165280; PMCID: PMC2733307.
      Citations: 67     Fields:    Translation:AnimalsCells
    36. Srinivasan RS, Dillard ME, Lagutin OV, Lin FJ, Tsai S, Tsai MJ, Samokhvalov IM, Oliver G. Lineage tracing demonstrates the venous origin of the mammalian lymphatic vasculature. Genes Dev. 2007 Oct 01; 21(19):2422-32. PMID: 17908929; PMCID: PMC1993873.
      Citations: 239     Fields:    Translation:AnimalsCells
    37. Cho JH, Klein WH, Tsai MJ. Compensational regulation of bHLH transcription factors in the postnatal development of BETA2/NeuroD1-null retina. Mech Dev. 2007 Aug; 124(7-8):543-50. PMID: 17629466; PMCID: PMC4300853.
      Citations: 9     Fields:    Translation:AnimalsCells
    38. Lee K, Jeong J, Tsai MJ, Tsai S, Lydon JP, DeMayo FJ. Molecular mechanisms involved in progesterone receptor regulation of uterine function. J Steroid Biochem Mol Biol. 2006 Dec; 102(1-5):41-50. PMID: 17067792; PMCID: PMC2562605.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    39. Wang J, Cortina G, Wu SV, Tran R, Cho JH, Tsai MJ, Bailey TJ, Jamrich M, Ament ME, Treem WR, Hill ID, Vargas JH, Gershman G, Farmer DG, Reyen L, Mart?n MG. Mutant neurogenin-3 in congenital malabsorptive diarrhea. N Engl J Med. 2006 Jul 20; 355(3):270-80. PMID: 16855267.
      Citations: 116     Fields:    Translation:HumansCells
    40. Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC. The emerging role of the PI3-K-Akt pathway in prostate cancer progression. Prostate Cancer Prostatic Dis. 2005; 8(2):108-18. PMID: 15724144.
      Citations: 54     Fields:    Translation:HumansCells
    41. Ichikawa H, Lin SC, Tsai SY, Tsai MJ, Sugimoto T. Effect of mCOUP-TF1 deficiency on the glossopharyngeal and vagal sensory ganglia. Brain Res. 2004 Jul 16; 1014(1-2):247-50. PMID: 15213010.
      Citations:    Fields:    Translation:AnimalsCells
    42. Kim JY, Chu K, Kim HJ, Seong HA, Park KC, Sanyal S, Takeda J, Ha H, Shong M, Tsai MJ, Choi HS. Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD. Mol Endocrinol. 2004 Apr; 18(4):776-90. PMID: 14752053.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    43. Poulin G, Chu K, Tsai MJ, Drouin J, Lamolet B, Guillemot F. Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr; 18(4):995-1003. PMID: 14726486.
      Citations: 26     Fields:    Translation:Animals
    44. Wright ME, Tsai MJ, Aebersold R. Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. Mol Endocrinol. 2003 Sep; 17(9):1726-37. PMID: 12775765.
      Citations: 65     Fields:    Translation:HumansCells
    45. Navab R, Wang Y, Chow YH, Wang A, Jankov RP, Takamoto N, Tsai SY, Tsai MJ, Tanswell AK, Hu J. Regulation of human Clara cell 10 kD protein expression by chicken ovalbumin upstream promoter transcription factors (COUP-TFs). Am J Respir Cell Mol Biol. 2002 Sep; 27(3):273-85. PMID: 12204889.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    46. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin. Proc Natl Acad Sci U S A. 2001 Oct 23; 98(22):12426-31. PMID: 11606780; PMCID: PMC60070.
      Citations: 40     Fields:    Translation:HumansCells
    47. Zhou C, Tsai SY, Tsai MJ. COUP-TFI: an intrinsic factor for early regionalization of the neocortex. Genes Dev. 2001 Aug 15; 15(16):2054-9. PMID: 11511537; PMCID: PMC312763.
      Citations: 59     Fields:    Translation:Animals
    48. Cooney AJ, Lee CT, Lin SC, Tsai SY, Tsai MJ. Physiological function of the orphans GCNF and COUP-TF. Trends Endocrinol Metab. 2001 Aug; 12(6):247-51. PMID: 11445441.
      Citations: 9     Fields:    Translation:HumansAnimals
    49. Liu J, Lin C, Gleiberman A, Ohgi KA, Herman T, Huang HP, Tsai MJ, Rosenfeld MG. Tbx19, a tissue-selective regulator of POMC gene expression. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8674-9. PMID: 11447259; PMCID: PMC37494.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    50. Cho JH, Kwon IS, Kim S, Ghil SH, Tsai MJ, Kim YS, Lee YD, Suh-Kim H. Overexpression of BETA2/NeuroD induces neurite outgrowth in F11 neuroblastoma cells. J Neurochem. 2001 Apr; 77(1):103-9. PMID: 11279266.
      Citations: 9     Fields:    Translation:AnimalsCells
    51. Chu K, Nemoz-Gaillard E, Tsai MJ. BETA2 and pancreatic islet development. Recent Prog Horm Res. 2001; 56:23-46. PMID: 11237215.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    52. Liu M, Pereira FA, Price SD, Chu MJ, Shope C, Himes D, Eatock RA, Brownell WE, Lysakowski A, Tsai MJ. Essential role of BETA2/NeuroD1 in development of the vestibular and auditory systems. Genes Dev. 2000 Nov 15; 14(22):2839-54. PMID: 11090132; PMCID: PMC317056.
      Citations: 107     Fields:    Translation:AnimalsCells
    53. Pereira FA, Tsai MJ, Tsai SY. COUP-TF orphan nuclear receptors in development and differentiation. Cell Mol Life Sci. 2000 Sep; 57(10):1388-98. PMID: 11078018.
      Citations: 76     Fields:    Translation:HumansAnimals
    54. Bartholomae A, Heimrich B, Feldmeyer D, Druffel-Augustin S, Goebbels S, Naya FJ, Zhao S, Frotscher M, Tsai MJ, Nave KA, Schwab MH. Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus. J Neurosci. 2000 May 15; 20(10):3714-24. PMID: 10804213; PMCID: PMC6772686.
      Citations: 103     Fields:    Translation:AnimalsCells
    55. Huang HP, Liu M, El-Hodiri HM, Chu K, Jamrich M, Tsai MJ. Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol Cell Biol. 2000 May; 20(9):3292-307. PMID: 10757813; PMCID: PMC85623.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    56. Liu M, Pleasure SJ, Collins AE, Noebels JL, Naya FJ, Tsai MJ, Lowenstein DH. Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy. Proc Natl Acad Sci U S A. 2000 Jan 18; 97(2):865-70. PMID: 10639171; PMCID: PMC15422.
      Citations: 116     Fields:    Translation:AnimalsCells
    57. Huang HP, Tsai MJ. Transcription factors involved in pancreatic islet development. J Biomed Sci. 2000 Jan-Feb; 7(1):27-34. PMID: 10644886.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    58. Bramblett DE, Huang HP, Tsai MJ. Pancreatic islet development. Adv Pharmacol. 2000; 47:255-315. PMID: 10582089.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    59. Zhou C, Qiu Y, Pereira FA, Crair MC, Tsai SY, Tsai MJ. The nuclear orphan receptor COUP-TFI is required for differentiation of subplate neurons and guidance of thalamocortical axons. Neuron. 1999 Dec; 24(4):847-59. PMID: 10624948.
      Citations: 69     Fields:    Translation:AnimalsCells
    60. Lu S, Tsai SY, Tsai MJ. Molecular mechanisms of androgen-independent growth of human prostate cancer LNCaP-AI cells. Endocrinology. 1999 Nov; 140(11):5054-9. PMID: 10537131.
      Citations: 32     Fields:    Translation:HumansCells
    61. Rindi G, Ratineau C, Ronco A, Candusso ME, Tsai M, Leiter AB. Targeted ablation of secretin-producing cells in transgenic mice reveals a common differentiation pathway with multiple enteroendocrine cell lineages in the small intestine. Development. 1999 Sep; 126(18):4149-56. PMID: 10457023.
      Citations: 27     Fields:    Translation:AnimalsCells
    62. Liu Z, Wong J, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 (SRC-1) enhances ligand-dependent and receptor-dependent cell-free transcription of chromatin. Proc Natl Acad Sci U S A. 1999 Aug 17; 96(17):9485-90. PMID: 10449719; PMCID: PMC22235.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    63. Pereira FA, Qiu Y, Zhou G, Tsai MJ, Tsai SY. The orphan nuclear receptor COUP-TFII is required for angiogenesis and heart development. Genes Dev. 1999 Apr 15; 13(8):1037-49. PMID: 10215630; PMCID: PMC316637.
      Citations: 188     Fields:    Translation:Animals
    64. Lanz RB, McKenna NJ, Onate SA, Albrecht U, Wong J, Tsai SY, Tsai MJ, O'Malley BW. A steroid receptor coactivator, SRA, functions as an RNA and is present in an SRC-1 complex. Cell. 1999 Apr 02; 97(1):17-27. PMID: 10199399.
      Citations: 284     Fields:    Translation:HumansAnimalsCells
    65. McKenna NJ, Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Nuclear receptor coactivators: multiple enzymes, multiple complexes, multiple functions. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):3-12. PMID: 10418975.
      Citations: 80     Fields:    Translation:HumansAnimals
    66. Ma ZQ, Tsai MJ, Tsai SY. Suppression of gene expression by tethering KRAB domain to promoter of ER target genes. J Steroid Biochem Mol Biol. 1999 Apr-Jun; 69(1-6):155-63. PMID: 10418989.
      Citations: 2     Fields:    Translation:HumansCells
    67. Tsai SY, Tsai MJ, Pipa?n C. COUP-TF upregulates NGFI-A gene expression through an Sp1 binding site. Mol Cell Biol. 1999 Apr; 19(4):2734-45. PMID: 10082539; PMCID: PMC84066.
      Citations: 37     Fields:    Translation:AnimalsCells
    68. Lu S, Liu M, Epner DE, Tsai SY, Tsai MJ. Androgen regulation of the cyclin-dependent kinase inhibitor p21 gene through an androgen response element in the proximal promoter. Mol Endocrinol. 1999 Mar; 13(3):376-84. PMID: 10076995.
      Citations: 55     Fields:    Translation:HumansCells
    69. Nawaz Z, Lonard DM, Smith CL, Lev-Lehman E, Tsai SY, Tsai MJ, O'Malley BW. The Angelman syndrome-associated protein, E6-AP, is a coactivator for the nuclear hormone receptor superfamily. Mol Cell Biol. 1999 Feb; 19(2):1182-9. PMID: 9891052; PMCID: PMC116047.
      Citations: 150     Fields:    Translation:HumansCells
    70. McKenna NJ, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. Distinct steady-state nuclear receptor coregulator complexes exist in vivo. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11697-702. PMID: 9751728; PMCID: PMC21703.
      Citations: 50     Fields:    Translation:HumansCells
    71. Onate SA, Boonyaratanakornkit V, Spencer TE, Tsai SY, Tsai MJ, Edwards DP, O'Malley BW. The steroid receptor coactivator-1 contains multiple receptor interacting and activation domains that cooperatively enhance the activation function 1 (AF1) and AF2 domains of steroid receptors. J Biol Chem. 1998 May 15; 273(20):12101-8. PMID: 9575154.
      Citations: 105     Fields:    Translation:HumansCells
    72. Xu J, Qiu Y, DeMayo FJ, Tsai SY, Tsai MJ, O'Malley BW. Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene. Science. 1998 Mar 20; 279(5358):1922-5. PMID: 9506940.
      Citations: 192     Fields:    Translation:AnimalsCells
    73. Mutoh H, Naya FJ, Tsai MJ, Leiter AB. The basic helix-loop-helix protein BETA2 interacts with p300 to coordinate differentiation of secretin-expressing enteroendocrine cells. Genes Dev. 1998 Mar 15; 12(6):820-30. PMID: 9512516; PMCID: PMC316627.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    74. Krishnan V, Pereira FA, Qiu Y, Chen CH, Beachy PA, Tsai SY, Tsai MJ. Mediation of Sonic hedgehog-induced expression of COUP-TFII by a protein phosphatase. Science. 1997 Dec 12; 278(5345):1947-50. PMID: 9395397.
      Citations: 42     Fields:    Translation:AnimalsCells
    75. Lu S, Tsai SY, Tsai MJ. Regulation of androgen-dependent prostatic cancer cell growth: androgen regulation of CDK2, CDK4, and CKI p16 genes. Cancer Res. 1997 Oct 15; 57(20):4511-6. PMID: 9377562.
      Citations: 35     Fields:    Translation:HumansCells
    76. Naya FJ, Huang HP, Qiu Y, Mutoh H, DeMayo FJ, Leiter AB, Tsai MJ. Diabetes, defective pancreatic morphogenesis, and abnormal enteroendocrine differentiation in BETA2/neuroD-deficient mice. Genes Dev. 1997 Sep 15; 11(18):2323-34. PMID: 9308961; PMCID: PMC316513.
      Citations: 327     Fields:    Translation:AnimalsCells
    77. Spencer TE, Jenster G, Burcin MM, Allis CD, Zhou J, Mizzen CA, McKenna NJ, Onate SA, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor coactivator-1 is a histone acetyltransferase. Nature. 1997 Sep 11; 389(6647):194-8. PMID: 9296499.
      Citations: 307     Fields:    Translation:HumansAnimalsCells
    78. Krishnan V, Elberg G, Tsai MJ, Tsai SY. Identification of a novel sonic hedgehog response element in the chicken ovalbumin upstream promoter-transcription factor II promoter. Mol Endocrinol. 1997 Sep; 11(10):1458-66. PMID: 9280061.
      Citations: 19     Fields:    Translation:AnimalsCells
    79. Chang KH, Chen Y, Chen TT, Chou WH, Chen PL, Ma YY, Yang-Feng TL, Leng X, Tsai MJ, O'Malley BW, Lee WH. A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein. Proc Natl Acad Sci U S A. 1997 Aug 19; 94(17):9040-5. PMID: 9256431; PMCID: PMC23019.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    80. Qiu Y, Pereira FA, DeMayo FJ, Lydon JP, Tsai SY, Tsai MJ. Null mutation of mCOUP-TFI results in defects in morphogenesis of the glossopharyngeal ganglion, axonal projection, and arborization. Genes Dev. 1997 Aug 01; 11(15):1925-37. PMID: 9271116; PMCID: PMC316414.
      Citations: 82     Fields:    Translation:AnimalsCells
    81. Jenster G, Spencer TE, Burcin MM, Tsai SY, Tsai MJ, O'Malley BW. Steroid receptor induction of gene transcription: a two-step model. Proc Natl Acad Sci U S A. 1997 Jul 22; 94(15):7879-84. PMID: 9223281; PMCID: PMC21523.
      Citations: 52     Fields:    Translation:HumansCells
    82. Shibata H, Nawaz Z, Tsai SY, O'Malley BW, Tsai MJ. Gene silencing by chicken ovalbumin upstream promoter-transcription factor I (COUP-TFI) is mediated by transcriptional corepressors, nuclear receptor-corepressor (N-CoR) and silencing mediator for retinoic acid receptor and thyroid hormone receptor (SMRT). Mol Endocrinol. 1997 Jun; 11(6):714-24. PMID: 9171235.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    83. Owerbach D, Naya FJ, Tsai MJ, Allander SV, Powell DR, Gabbay KH. Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35. Diabetes. 1997 Jun; 46(6):1069-74. PMID: 9166681.
      Citations: 7     Fields:    Translation:HumansCells
    84. Mutoh H, Fung BP, Naya FJ, Tsai MJ, Nishitani J, Leiter AB. The basic helix-loop-helix transcription factor BETA2/NeuroD is expressed in mammalian enteroendocrine cells and activates secretin gene expression. Proc Natl Acad Sci U S A. 1997 Apr 15; 94(8):3560-4. PMID: 9108015; PMCID: PMC20478.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    85. Tsai SY, Tsai MJ. Chick ovalbumin upstream promoter-transcription factors (COUP-TFs): coming of age. Endocr Rev. 1997 Apr; 18(2):229-40. PMID: 9101138.
      Citations: 126     Fields:    Translation:HumansAnimalsCells
    86. Stellrecht CM, DeMayo FJ, Finegold MJ, Tsai MJ. Tissue-specific and developmental regulation of the rat insulin II gene enhancer, RIPE3, in transgenic mice. J Biol Chem. 1997 Feb 07; 272(6):3567-72. PMID: 9013607.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    87. Shibata H, Spencer TE, Jenster G, Tsai SY, Tsai MJ, O'Malley BW, O?ate SA. Role of co-activators and co-repressors in the mechanism of steroid/thyroid receptor action. Recent Prog Horm Res. 1997; 52:141-64; discussion 164-5. PMID: 9238851.
      Citations: 101     Fields:    Translation:HumansAnimalsCells
    88. Kieback DG, Levi T, Kohlberger P, Fiedrich U, Press MF, Rosenthal HE, Runnebaum IB, Tong XW, Tsai MJ, M?bus VJ. Chicken ovalbumin upstream promoter--transcription factor (COUP-TF) expression in human endometrial cancer cell lines. Anticancer Res. 1996 Nov-Dec; 16(6B):3371-6. PMID: 9042194.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    89. Wang IM, Blanco JC, Tsai SY, Tsai MJ, Ozato K. Interferon regulatory factors and TFIIB cooperatively regulate interferon-responsive promoter activity in vivo and in vitro. Mol Cell Biol. 1996 Nov; 16(11):6313-24. PMID: 8887661; PMCID: PMC231634.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    90. Xu J, Nawaz Z, Tsai SY, Tsai MJ, O'Malley BW. The extreme C terminus of progesterone receptor contains a transcriptional repressor domain that functions through a putative corepressor. Proc Natl Acad Sci U S A. 1996 Oct 29; 93(22):12195-9. PMID: 8901556; PMCID: PMC37966.
      Citations: 17     Fields:    Translation:HumansCells
    91. McInerney EM, Tsai MJ, O'Malley BW, Katzenellenbogen BS. Analysis of estrogen receptor transcriptional enhancement by a nuclear hormone receptor coactivator. Proc Natl Acad Sci U S A. 1996 Sep 17; 93(19):10069-73. PMID: 8816752; PMCID: PMC38337.
      Citations: 50     Fields:    Translation:HumansAnimalsCells
    92. Smith CL, Tsai MJ, O'Malley BW, O?ate SA. CREB binding protein acts synergistically with steroid receptor coactivator-1 to enhance steroid receptor-dependent transcription. Proc Natl Acad Sci U S A. 1996 Aug 20; 93(17):8884-8. PMID: 8799122; PMCID: PMC38563.
      Citations: 88     Fields:    Translation:HumansCells
    93. Leng X, Cooney AJ, Tsai SY, Tsai MJ. Molecular mechanisms of COUP-TF-mediated transcriptional repression: evidence for transrepression and active repression. Mol Cell Biol. 1996 May; 16(5):2332-40. PMID: 8628300; PMCID: PMC231221.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    94. Peyton M, Stellrecht CM, Naya FJ, Huang HP, Samora PJ, Tsai MJ. BETA3, a novel helix-loop-helix protein, can act as a negative regulator of BETA2 and MyoD-responsive genes. Mol Cell Biol. 1996 Feb; 16(2):626-33. PMID: 8552091; PMCID: PMC231042.
      Citations: 18     Fields:    Translation:AnimalsCells
    95. Qiu Y, Krishnan V, Pereira FA, Tsai SY, Tsai MJ. Chicken ovalbumin upstream promoter-transcription factors and their regulation. J Steroid Biochem Mol Biol. 1996 Jan; 56(1-6 Spec No):81-5. PMID: 8603050.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    96. Nawaz Z, Tsai MJ, O'Malley BW. Specific mutations in the ligand binding domain selectively abolish the silencing function of human thyroid hormone receptor beta. Proc Natl Acad Sci U S A. 1995 Dec 05; 92(25):11691-5. PMID: 8524830; PMCID: PMC40468.
      Citations: 2     Fields:    Translation:HumansCells
    97. Tsai SY, Tsai MJ, O'Malley BW, O?ate SA. Sequence and characterization of a coactivator for the steroid hormone receptor superfamily. Science. 1995 Nov 24; 270(5240):1354-7. PMID: 7481822.
      Citations: 550     Fields:    Translation:HumansCells
    98. Feng JQ, Chen D, Cooney AJ, Tsai MJ, Harris MA, Tsai SY, Feng M, Mundy GR, Harris SE. The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptor. J Biol Chem. 1995 Nov 24; 270(47):28364-73. PMID: 7499338.
      Citations: 22     Fields:    Translation:AnimalsCells
    99. Burris TP, Nawaz Z, Tsai MJ, O'Malley BW. A nuclear hormone receptor-associated protein that inhibits transactivation by the thyroid hormone and retinoic acid receptors. Proc Natl Acad Sci U S A. 1995 Oct 10; 92(21):9525-9. PMID: 7568167; PMCID: PMC40834.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    100. Shieh SY, Stellrecht CM, Tsai MJ. Molecular characterization of the rat insulin enhancer-binding complex 3b2. Cloning of a binding factor with putative helicase motifs. J Biol Chem. 1995 Sep 15; 270(37):21503-8. PMID: 7665561.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    101. Qiu Y, Krishnan V, Zeng Z, Gilbert DJ, Copeland NG, Gibson L, Yang-Feng T, Jenkins NA, Tsai MJ, Tsai SY. Isolation, characterization, and chromosomal localization of mouse and human COUP-TF I and II genes. Genomics. 1995 Sep 01; 29(1):240-6. PMID: 8530078.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    102. Pereira FA, Qiu Y, Tsai MJ, Tsai SY. Chicken ovalbumin upstream promoter transcription factor (COUP-TF): expression during mouse embryogenesis. J Steroid Biochem Mol Biol. 1995 Jun; 53(1-6):503-8. PMID: 7626501.
      Citations: 32     Fields:    Translation:Animals
    103. Naya FJ, Stellrecht CM, Tsai MJ. Tissue-specific regulation of the insulin gene by a novel basic helix-loop-helix transcription factor. Genes Dev. 1995 Apr 15; 9(8):1009-19. PMID: 7774807.
      Citations: 196     Fields:    Translation:AnimalsCells
    104. Blanco JC, Wang IM, Tsai SY, Tsai MJ, O'Malley BW, Jurutka PW, Haussler MR, Ozato K. Transcription factor TFIIB and the vitamin D receptor cooperatively activate ligand-dependent transcription. Proc Natl Acad Sci U S A. 1995 Feb 28; 92(5):1535-9. PMID: 7878015; PMCID: PMC42554.
      Citations: 28     Fields:    Translation:HumansCells
    105. Bagchi MK, Tsai SY, Tsai MJ. In vitro reconstitution of progesterone-dependent RNA transcription in nuclear extracts of human breast carcinoma cells. Methods Mol Biol. 1995; 37:107-20. PMID: 7780500.
      Citations: 1     Fields:    Translation:HumansCells
    106. Baniahmad C, Nawaz Z, Baniahmad A, Gleeson MA, Tsai MJ, O'Malley BW. Enhancement of human estrogen receptor activity by SPT6: a potential coactivator. Mol Endocrinol. 1995 Jan; 9(1):34-43. PMID: 7760849.
      Citations: 20     Fields:    Translation:AnimalsCells
    107. Leng X, Blanco J, Tsai SY, Ozato K, O'Malley BW, Tsai MJ. Mechanisms for synergistic activation of thyroid hormone receptor and retinoid X receptor on different response elements. J Biol Chem. 1994 Dec 16; 269(50):31436-42. PMID: 7989311.
      Citations: 12     Fields:    Translation:Cells
    108. Nawaz Z, Baniahmad C, Burris TP, Stillman DJ, O'Malley BW, Tsai MJ. The yeast SIN3 gene product negatively regulates the activity of the human progesterone receptor and positively regulates the activities of GAL4 and the HAP1 activator. Mol Gen Genet. 1994 Dec 15; 245(6):724-33. PMID: 7830720.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    109. Peyton M, Moss LG, Tsai MJ. Two distinct class A helix-loop-helix transcription factors, E2A and BETA1, form separate DNA binding complexes on the insulin gene E box. J Biol Chem. 1994 Oct 14; 269(41):25936-41. PMID: 7929299.
      Citations: 14     Fields:    Translation:AnimalsCells
    110. Liu X, Ge R, Westmoreland S, Cooney AJ, Tsai SY, Tsai MJ, Ricciardi RP. Negative regulation by the R2 element of the MHC class I enhancer in adenovirus-12 transformed cells correlates with high levels of COUP-TF binding. Oncogene. 1994 Aug; 9(8):2183-90. PMID: 8036004.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    111. Zeng Z, Allan GF, Thaller C, Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Detection of potential ligands for nuclear receptors in cellular extracts. Endocrinology. 1994 Jul; 135(1):248-52. PMID: 8013359.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    112. Burbach JP, Lopes da Silva S, Cox JJ, Adan RA, Cooney AJ, Tsai MJ, Tsai SY. Repression of estrogen-dependent stimulation of the oxytocin gene by chicken ovalbumin upstream promoter transcription factor I. J Biol Chem. 1994 May 27; 269(21):15046-53. PMID: 8195142.
      Citations: 19     Fields:    Translation:AnimalsCells
    113. Qiu Y, Cooney AJ, Kuratani S, DeMayo FJ, Tsai SY, Tsai MJ. Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A. 1994 May 10; 91(10):4451-5. PMID: 8183930; PMCID: PMC43803.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    114. Robinson GL, Peshavaria M, Henderson E, Shieh SY, Tsai MJ, Teitelman G, Stein R. Expression of the trans-active factors that stimulate insulin control element-mediated activity appear to precede insulin gene transcription. J Biol Chem. 1994 Jan 28; 269(4):2452-60. PMID: 8300572.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    115. Tsai MJ, O'Malley BW. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu Rev Biochem. 1994; 63:451-86. PMID: 7979245.
      Citations: 669     Fields:    Translation:AnimalsCells
    116. Lutz B, Kuratani S, Cooney AJ, Wawersik S, Tsai SY, Eichele G, Tsai MJ. Developmental regulation of the orphan receptor COUP-TF II gene in spinal motor neurons. Development. 1994 Jan; 120(1):25-36. PMID: 8119130.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    117. Leng X, Tsai SY, O'Malley BW, Tsai MJ. Ligand-dependent conformational changes in thyroid hormone and retinoic acid receptors are potentially enhanced by heterodimerization with retinoic X receptor. J Steroid Biochem Mol Biol. 1993 Dec; 46(6):643-61. PMID: 8274399.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    118. Kieback DG, Runnebaum IB, Moebus VJ, Kreienberg R, McCamant SK, Edwards CL, Jones LA, Tsai MJ, O'Malley BW. Chicken ovalbumin upstream promoter transcription factor (COUP-TF): an orphan steroid receptor with a specific pattern of differential expression in human ovarian cancer cell lines. Gynecol Oncol. 1993 Nov; 51(2):167-70. PMID: 7903949.
      Citations: 4     Fields:    Translation:HumansCells
    119. Beekman JM, Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Transcriptional activation by the estrogen receptor requires a conformational change in the ligand binding domain. Mol Endocrinol. 1993 Oct; 7(10):1266-74. PMID: 8264659.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    120. Baniahmad A, Ha I, Reinberg D, Tsai S, Tsai MJ, O'Malley BW. Interaction of human thyroid hormone receptor beta with transcription factor TFIIB may mediate target gene derepression and activation by thyroid hormone. Proc Natl Acad Sci U S A. 1993 Oct 01; 90(19):8832-6. PMID: 8415616; PMCID: PMC47454.
      Citations: 111     Fields:    Translation:HumansCells
    121. Ing NH, Beekman JM, Kessler DJ, Murphy M, Jayaraman K, Zendegui JG, Hogan ME, O'Malley BW, Tsai MJ. In vivo transcription of a progesterone-responsive gene is specifically inhibited by a triplex-forming oligonucleotide. Nucleic Acids Res. 1993 Jun 25; 21(12):2789-96. PMID: 8332487; PMCID: PMC309654.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    122. Cooney AJ, Leng X, Tsai SY, O'Malley BW, Tsai MJ. Multiple mechanisms of chicken ovalbumin upstream promoter transcription factor-dependent repression of transactivation by the vitamin D, thyroid hormone, and retinoic acid receptors. J Biol Chem. 1993 Feb 25; 268(6):4152-60. PMID: 8382695.
      Citations: 60     Fields:    Translation:AnimalsCells
    123. Baniahmad A, Tsai MJ. Mechanisms of transcriptional activation by steroid hormone receptors. J Cell Biochem. 1993 Feb; 51(2):151-6. PMID: 8440749.
      Citations: 6     Fields:    Translation:HumansAnimals
    124. Allan GF, Tsai SY, Tsai MJ, O'Malley BW. Ligand-dependent conformational changes in the progesterone receptor are necessary for events that follow DNA binding. Proc Natl Acad Sci U S A. 1992 Dec 15; 89(24):11750-4. PMID: 1465392; PMCID: PMC50634.
      Citations: 21     Fields:    Translation:HumansCells
    125. Baniahmad A, Tsai SY, O'Malley BW, Tsai MJ. Kindred S thyroid hormone receptor is an active and constitutive silencer and a repressor for thyroid hormone and retinoic acid responses. Proc Natl Acad Sci U S A. 1992 Nov 15; 89(22):10633-7. PMID: 1359543; PMCID: PMC50395.
      Citations: 32     Fields:    Translation:HumansCells
    126. Allan GF, Leng X, Tsai SY, Weigel NL, Edwards DP, Tsai MJ, O'Malley BW. Hormone and antihormone induce distinct conformational changes which are central to steroid receptor activation. J Biol Chem. 1992 Sep 25; 267(27):19513-20. PMID: 1326555.
      Citations: 63     Fields:    Translation:HumansCells
    127. Ing NH, Beekman JM, Tsai SY, Tsai MJ, O'Malley BW. Members of the steroid hormone receptor superfamily interact with TFIIB (S300-II). J Biol Chem. 1992 Sep 05; 267(25):17617-23. PMID: 1517211.
      Citations: 96     Fields:    Translation:HumansCells
    128. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors. Mol Cell Biol. 1992 Sep; 12(9):4153-63. PMID: 1324415; PMCID: PMC360317.
      Citations: 127     Fields:    Translation:AnimalsCells
    129. Bagchi MK, Tsai MJ, O'Malley BW, Tsai SY. Analysis of the mechanism of steroid hormone receptor-dependent gene activation in cell-free systems. Endocr Rev. 1992 Aug; 13(3):525-35. PMID: 1425487.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    130. Vegeto E, Allan GF, Schrader WT, Tsai MJ, McDonnell DP, O'Malley BW. The mechanism of RU486 antagonism is dependent on the conformation of the carboxy-terminal tail of the human progesterone receptor. Cell. 1992 May 15; 69(4):703-13. PMID: 1586949.
      Citations: 85     Fields:    Translation:HumansAnimalsCells
    131. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Ligand and DNA-dependent phosphorylation of human progesterone receptor in vitro. Proc Natl Acad Sci U S A. 1992 Apr 01; 89(7):2664-8. PMID: 1557371; PMCID: PMC48722.
      Citations: 14     Fields:    Translation:HumansCells
    132. Elliston JF, Beekman JM, Tsai SY, O'Malley BW, Tsai MJ. Hormone activation of baculovirus expressed progesterone receptors. J Biol Chem. 1992 Mar 15; 267(8):5193-8. PMID: 1544902.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    133. Lee JK, Tam JW, Tsai MJ, Tsai SY. Identification of cis- and trans-acting factors regulating the expression of the human insulin receptor gene. J Biol Chem. 1992 Mar 05; 267(7):4638-45. PMID: 1311316.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    134. Pham TA, McDonnell DP, Tsai MJ, O'Malley BW. Modulation of progesterone receptor binding to progesterone response elements by positioned nucleosomes. Biochemistry. 1992 Feb 11; 31(5):1570-8. PMID: 1737013.
      Citations: 4     Fields:    Translation:AnimalsCells
    135. O'Malley BW, Tsai MJ. Molecular pathways of steroid receptor action. Biol Reprod. 1992 Feb; 46(2):163-7. PMID: 1536890.
      Citations: 50     Fields:    Translation:HumansAnimals
    136. Nawaz Z, Tsai MJ, McDonnell DP, O'Malley BW. Identification of novel steroid-response elements. Gene Expr. 1992; 2(1):39-47. PMID: 1617301; PMCID: PMC6057364.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    137. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Progesterone enhances target gene transcription by receptor free of heat shock proteins hsp90, hsp56, and hsp70. Mol Cell Biol. 1991 Oct; 11(10):4998-5004. PMID: 1922029; PMCID: PMC361487.
      Citations: 14     Fields:    Translation:HumansCells
    138. Shieh SY, Tsai MJ. Cell-specific and ubiquitous factors are responsible for the enhancer activity of the rat insulin II gene. J Biol Chem. 1991 Sep 05; 266(25):16708-14. PMID: 1885600.
      Citations: 44     Fields:    Translation:AnimalsCells
    139. Bradshaw MS, Tsai SY, Leng XH, Dobson AD, Conneely OM, O'Malley BW, Tsai MJ. Studies on the mechanism of functional cooperativity between progesterone and estrogen receptors. J Biol Chem. 1991 Sep 05; 266(25):16684-90. PMID: 1885597.
      Citations: 8     Fields:    Translation:Cells
    140. Cooney AJ, Tsai SY, O'Malley BW, Tsai MJ. Chicken ovalbumin upstream promoter transcription factor binds to a negative regulatory region in the human immunodeficiency virus type 1 long terminal repeat. J Virol. 1991 Jun; 65(6):2853-60. PMID: 2033658; PMCID: PMC240909.
      Citations: 32     Fields:    Translation:HumansCells
    141. Pham TA, Elliston JF, Nawaz Z, McDonnell DP, Tsai MJ, O'Malley BW. Antiestrogen can establish nonproductive receptor complexes and alter chromatin structure at target enhancers. Proc Natl Acad Sci U S A. 1991 Apr 15; 88(8):3125-9. PMID: 2014231; PMCID: PMC51398.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    142. Allan GF, Ing NH, Tsai SY, Srinivasan G, Weigel NL, Thompson EB, Tsai MJ, O'Malley BW. Synergism between steroid response and promoter elements during cell-free transcription. J Biol Chem. 1991 Mar 25; 266(9):5905-10. PMID: 2005127.
      Citations: 10     Fields:    Translation:AnimalsCells
    143. Allan GF, Tsai SY, O'Malley BW, Tsai MJ. Steroid hormone receptors and in vitro transcription. Bioessays. 1991 Feb; 13(2):73-8. PMID: 2029268.
      Citations: 1     Fields:    Translation:AnimalsCells
    144. Wang LH, Ing NH, Tsai SY, O'Malley BW, Tsai MJ. The COUP-TFs compose a family of functionally related transcription factors. Gene Expr. 1991; 1(3):207-16. PMID: 1820218; PMCID: PMC5952191.
      Citations: 42     Fields:    Translation:HumansCells
    145. O'Malley BW, Tsai SY, Bagchi M, Weigel NL, Schrader WT, Tsai MJ. Molecular mechanism of action of a steroid hormone receptor. Recent Prog Horm Res. 1991; 47:1-24; discussion 24-6. PMID: 1745818.
      Citations: 7     Fields:    Translation:AnimalsCells
    146. Ritchie HH, Wang LH, Tsai S, O'Malley BW, Tsai MJ. COUP-TF gene: a structure unique for the steroid/thyroid receptor superfamily. Nucleic Acids Res. 1990 Dec 11; 18(23):6857-62. PMID: 2263450; PMCID: PMC332742.
      Citations: 13     Fields:    Translation:HumansCells
    147. Elliston JF, Fawell SE, Klein-Hitpass L, Tsai SY, Tsai MJ, Parker MG, O'Malley BW. Mechanism of estrogen receptor-dependent transcription in a cell-free system. Mol Cell Biol. 1990 Dec; 10(12):6607-12. PMID: 2247075; PMCID: PMC362937.
      Citations: 16     Fields:    Translation:AnimalsCells
    148. Tsai SY, Srinivasan G, Allan GF, Thompson EB, O'Malley BW, Tsai MJ. Recombinant human glucocorticoid receptor induces transcription of hormone response genes in vitro. J Biol Chem. 1990 Oct 05; 265(28):17055-61. PMID: 2170364.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    149. Elliston JF, Tsai SY, O'Malley BW, Tsai MJ. Superactive estrogen receptors. Potent activators of gene expression. J Biol Chem. 1990 Jul 15; 265(20):11517-21. PMID: 2164005.
      Citations: 6     Fields:    Translation:AnimalsCells
    150. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Identification of a functional intermediate in receptor activation in progesterone-dependent cell-free transcription. Nature. 1990 Jun 07; 345(6275):547-50. PMID: 2348863.
      Citations: 28     Fields:    Translation:HumansCells
    151. Hwung YP, Gu YZ, Tsai MJ. Cooperativity of sequence elements mediates tissue specificity of the rat insulin II gene. Mol Cell Biol. 1990 Apr; 10(4):1784-8. PMID: 2181285; PMCID: PMC362286.
      Citations: 19     Fields:    Translation:AnimalsCells
    152. Bagchi MK, Tsai SY, Weigel NL, Tsai MJ, O'Malley BW. Regulation of in vitro transcription by progesterone receptor. Characterization and kinetic studies. J Biol Chem. 1990 Mar 25; 265(9):5129-34. PMID: 2318886.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    153. Klein-Hitpass L, Tsai SY, Weigel NL, Allan GF, Riley D, Rodriguez R, Schrader WT, Tsai MJ, O'Malley BW. The progesterone receptor stimulates cell-free transcription by enhancing the formation of a stable preinitiation complex. Cell. 1990 Jan 26; 60(2):247-57. PMID: 2153462.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    154. Conneely OM, Kettelberger DM, Tsai MJ, Schrader WT, O'Malley BW. The chicken progesterone receptor A and B isoforms are products of an alternate translation initiation event. J Biol Chem. 1989 Aug 25; 264(24):14062-4. PMID: 2760059.
      Citations: 33     Fields:    Translation:AnimalsCells
    155. Pastorcic M, Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Multiple protein binding sites within the ovalbumin gene 5'-flanking region: isolation and characterization of sequence-specific binding proteins. Nucleic Acids Res. 1989 Aug 25; 17(16):6693-711. PMID: 2780293; PMCID: PMC318360.
      Citations: 3     Fields:    Translation:AnimalsCells
    156. Wang LH, Tsai SY, Cook RG, Beattie WG, Tsai MJ, O'Malley BW. COUP transcription factor is a member of the steroid receptor superfamily. Nature. 1989 Jul 13; 340(6229):163-6. PMID: 2739739.
      Citations: 145     Fields:    Translation:AnimalsCells
    157. Tsai SY, Tsai MJ, O'Malley BW. Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements. Cell. 1989 May 05; 57(3):443-8. PMID: 2566384.
      Citations: 85     Fields:    Translation:AnimalsCells
    158. Crowe DT, Tsai MJ. Mutagenesis of the rat insulin II 5'-flanking region defines sequences important for expression in HIT cells. Mol Cell Biol. 1989 Apr; 9(4):1784-9. PMID: 2657405; PMCID: PMC362598.
      Citations: 43     Fields:    Translation:AnimalsCells
    159. Dobson AD, Conneely OM, Beattie W, Maxwell BL, Mak P, Tsai MJ, Schrader WT, O'Malley BW. Mutational analysis of the chicken progesterone receptor. J Biol Chem. 1989 Mar 05; 264(7):4207-11. PMID: 2917996.
      Citations: 9     Fields:    Translation:AnimalsCells
    160. Klein-Hitpass L, Tsai SY, Greene GL, Clark JH, Tsai MJ, O'Malley BW. Specific binding of estrogen receptor to the estrogen response element. Mol Cell Biol. 1989 Jan; 9(1):43-9. PMID: 2927397; PMCID: PMC362143.
      Citations: 42     Fields:    Translation:AnimalsCells
    161. Bagchi MK, Elliston JF, Tsai SY, Edwards DP, Tsai MJ, O'Malley BW. Steroid hormone-dependent interaction of human progesterone receptor with its target enhancer element. Mol Endocrinol. 1988 Dec; 2(12):1221-9. PMID: 3216861.
      Citations: 17     Fields:    Translation:HumansCells
    162. Bradshaw MS, Tsai MJ, O'Malley BW. A steroid response element can function in the absence of a distal promoter. Mol Endocrinol. 1988 Dec; 2(12):1286-93. PMID: 2905764.
      Citations: 3     Fields:    Translation:AnimalsCells
    163. Tsai SY, Carlstedt-Duke J, Weigel NL, Dahlman K, Gustafsson JA, Tsai MJ, O'Malley BW. Molecular interactions of steroid hormone receptor with its enhancer element: evidence for receptor dimer formation. Cell. 1988 Oct 21; 55(2):361-9. PMID: 3167984.
      Citations: 129     Fields:    Translation:AnimalsCells
    164. Conneely OM, Dobson AD, Carson MA, Maxwell BL, Tsai MJ, Schrader WT, O'Malley BW. Structure-function relationships of the chicken progesterone receptor. Biochem Soc Trans. 1988 Oct; 16(5):683-7. PMID: 2466711.
      Citations:    Fields:    Translation:HumansAnimals
    165. Hwung YP, Wang LH, Tsai SY, Tsai MJ. Differential binding of the chicken ovalbumin upstream promoter (COUP) transcription factor to two different promoters. J Biol Chem. 1988 Sep 15; 263(26):13470-4. PMID: 3047126.
      Citations: 14     Fields:    Translation:Cells
    166. Bradshaw MS, Tsai MJ, O'Malley BW. A far upstream ovalbumin enhancer binds nuclear factor-1-like factor. J Biol Chem. 1988 Jun 15; 263(17):8485-90. PMID: 3372538.
      Citations: 10     Fields:    Translation:AnimalsCells
    167. Hwung YP, Crowe DT, Wang LH, Tsai SY, Tsai MJ. The COUP transcription factor binds to an upstream promoter element of the rat insulin II gene. Mol Cell Biol. 1988 May; 8(5):2070-7. PMID: 3290646; PMCID: PMC363386.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    168. Tsai MJ, Tsai SY, Klein-Hitpass L, Bagchi M, Elliston JF, Carlstedt-Duke J, Gustafsson JA, Gustafsson JK, O'Malley BW. Cooperative interactions of steroid hormone receptors with their cognate response elements. Cold Spring Harb Symp Quant Biol. 1988; 53 Pt 2:829-33. PMID: 3254786.
      Citations:    Fields:    Translation:AnimalsCells
    169. Bagchi MK, Tsai SY, Tsai MJ, O'Malley BW. Purification and characterization of chicken ovalbumin gene upstream promoter transcription factor from homologous oviduct cells. Mol Cell Biol. 1987 Dec; 7(12):4151-8. PMID: 3437886; PMCID: PMC368095.
      Citations: 19     Fields:    Translation:AnimalsCells
    170. Huckaby CS, Conneely OM, Beattie WG, Dobson AD, Tsai MJ, O'Malley BW. Structure of the chromosomal chicken progesterone receptor gene. Proc Natl Acad Sci U S A. 1987 Dec; 84(23):8380-4. PMID: 3479797; PMCID: PMC299546.
      Citations: 22     Fields:    Translation:AnimalsCells
    171. Wang LH, Tsai SY, Sagami I, Tsai MJ, O'Malley BW. Purification and characterization of chicken ovalbumin upstream promoter transcription factor from HeLa cells. J Biol Chem. 1987 Nov 25; 262(33):16080-6. PMID: 3680243.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    172. Carson MA, Tsai MJ, Conneely OM, Maxwell BL, Clark JH, Dobson AD, Elbrecht A, Toft DO, Schrader WT, O'Malley BW. Structure-function properties of the chicken progesterone receptor A synthesized from complementary deoxyribonucleic acid. Mol Endocrinol. 1987 Nov; 1(11):791-801. PMID: 3153463.
      Citations: 8     Fields:    Translation:AnimalsCells
    173. Scott MJ, Tsai MJ, O'Malley BW. Deoxyribonuclease I sensitivity of the ovomucoid-ovoinhibitor gene complex in oviduct nuclei and relative location of CR1 repetitive sequences. Biochemistry. 1987 Oct 20; 26(21):6831-40. PMID: 2827735.
      Citations: 1     Fields:    Translation:AnimalsCells
    174. Tsai SY, Sagami I, Wang H, Tsai MJ, O'Malley BW. Interactions between a DNA-binding transcription factor (COUP) and a non-DNA binding factor (S300-II). Cell. 1987 Aug 28; 50(5):701-9. PMID: 3040258.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    175. Conneely OM, Dobson AD, Tsai MJ, Beattie WG, Toft DO, Huckaby CS, Zarucki T, Schrader WT, O'Malley BW. Sequence and expression of a functional chicken progesterone receptor. Mol Endocrinol. 1987 Aug; 1(8):517-25. PMID: 3153474.
      Citations: 8     Fields:    Translation:AnimalsCells
    176. Baez M, Sargan DR, Elbrecht A, Kulomaa MS, Zarucki-Schulz T, Tsai MJ, O'Malley BW. Steroid hormone regulation of the gene encoding the chicken heat shock protein hsp 108. J Biol Chem. 1987 May 15; 262(14):6582-8. PMID: 3571271.
      Citations: 7     Fields:    Translation:AnimalsCells
    177. Scott MJ, Huckaby CS, Kato I, Kohr WJ, Laskowski M, Tsai MJ, O'Malley BW. Ovoinhibitor introns specify functional domains as in the related and linked ovomucoid gene. J Biol Chem. 1987 Apr 25; 262(12):5899-907. PMID: 3571241.
      Citations: 11     Fields:    Translation:AnimalsCells
    178. Elbrecht A, DeMayo FJ, Tsai MJ, O'Malley BW. Episomal maintenance of a bovine papilloma virus vector in transgenic mice. Mol Cell Biol. 1987 Mar; 7(3):1276-9. PMID: 3031486; PMCID: PMC365203.
      Citations: 1     Fields:    Translation:AnimalsCells
    179. Kleinsek DA, Beattie WG, Tsai MJ, O'Malley BW. Molecular cloning of a steroid-regulated 108K heat shock protein gene from hen oviduct. Nucleic Acids Res. 1986 Dec 22; 14(24):10053-69. PMID: 3027654; PMCID: PMC341355.
      Citations: 6     Fields:    Translation:AnimalsCells
    180. Sagami I, Tsai SY, Wang H, Tsai MJ, O'Malley BW. Identification of two factors required for transcription of the ovalbumin gene. Mol Cell Biol. 1986 Dec; 6(12):4259-67. PMID: 3796602; PMCID: PMC367207.
      Citations: 62     Fields:    Translation:HumansCells
    181. Sargan DR, Tsai MJ, O'Malley BW. hsp108,,,,,, a novel heat shock inducible protein of chicken. Biochemistry. 1986 Oct 07; 25(20):6252-8. PMID: 3098286.
      Citations: 8     Fields:    Translation:AnimalsCells
    182. Pastorcic M, Wang H, Elbrecht A, Tsai SY, Tsai MJ, O'Malley BW. Control of transcription initiation in vitro requires binding of a transcription factor to the distal promoter of the ovalbumin gene. Mol Cell Biol. 1986 Aug; 6(8):2784-91. PMID: 3785213; PMCID: PMC367845.
      Citations: 39     Fields:    Translation:Cells
    183. O'Malley BW, Schrader WT, Tsai MJ. Molecular actions of steroid hormones. Adv Exp Med Biol. 1986; 196:1-10. PMID: 3012973.
      Citations: 1     Fields:    Translation:AnimalsCells
    184. Elbrecht A, Tsai SY, Tsai MJ, O'Malley BW. Identification by exonuclease footprinting of a distal promoter-binding protein from HeLa cell extracts. DNA. 1985 Jun; 4(3):233-40. PMID: 2988892.
      Citations: 5     Fields:    Translation:HumansCells
    185. Preshaw RM. Sex differences in morbidity and mortality from peptic ulcer in Canada, 1950-1981. Clin Invest Med. 1985; 8(1):62-7. PMID: 3987120.
      Citations:    Fields:    Translation:Humans
    186. Sanzo M, Stevens B, Tsai MJ, O'Malley BW. Isolation of a protein fraction that binds preferentially to chicken middle repetitive DNA. Biochemistry. 1984 Dec 18; 23(26):6491-8. PMID: 6543321.
      Citations: 7     Fields:    Translation:AnimalsCells
    187. Selvanayagam CS, Tsai SY, Tsai MJ, Selvanayagam P, Saunders GF. Multiple origins of transcription for the human placental lactogen genes. J Biol Chem. 1984 Dec 10; 259(23):14642-6. PMID: 6209277.
      Citations: 7     Fields:    Translation:HumansCells
    188. Stumph WE, Hodgson CP, Tsai MJ, O'Malley BW. Genomic structure and possible retroviral origin of the chicken CR1 repetitive DNA sequence family. Proc Natl Acad Sci U S A. 1984 Nov; 81(21):6667-71. PMID: 6593723; PMCID: PMC391991.
      Citations: 18     Fields:    Translation:AnimalsCells
    189. Tsai SY, Dicker P, Fang P, Tsai MJ, O'Malley BW. Generation of monoclonal antibodies to RNA polymerase II for the identification of transcriptional factors. J Biol Chem. 1984 Sep 25; 259(18):11587-93. PMID: 6381502.
      Citations: 4     Fields:    Translation:AnimalsCells
    190. Kristo P, Tsai MJ, O'Malley BW. Characterization of three chicken pseudogenes for U1 RNA. DNA. 1984 Aug; 3(4):281-6. PMID: 6207998.
      Citations: 2     Fields:    Translation:AnimalsCells
    191. Alevy MC, Tsai MJ, O'Malley BW. DNase I sensitive domain of the gene coding for the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase. Biochemistry. 1984 May 08; 23(10):2309-14. PMID: 6329271.
      Citations: 16     Fields:    Translation:AnimalsCells
    192. Dicker PD, Tsai SY, Weigel NL, Tsai MJ, Schrader WT, O'Malley BW. Monoclonal antibody to the hen oviduct progesterone receptor produced following in vitro immunization. J Steroid Biochem. 1984 Jan; 20(1):43-50. PMID: 6538613.
      Citations:    Fields:    Translation:AnimalsPHPublic Health
    193. Ciejek EM, Tsai MJ, O'Malley BW. Actively transcribed genes are associated with the nuclear matrix. Nature. 1983 Dec 8-14; 306(5943):607-9. PMID: 6646237.
      Citations: 84     Fields:    Translation:AnimalsCells
    194. Shen XZ, Tsai MJ, Bullock DW, Woo SL. Hormonal regulation of rabbit uteroglobin gene transcription. Endocrinology. 1983 Mar; 112(3):871-6. PMID: 6185330.
      Citations: 3     Fields:    Translation:AnimalsCells
    195. Stumph WE, Baez M, Beattie WG, Tsai MJ, O'Malley BW. Characterization of deoxyribonucleic acid sequences at the 5' and 3' borders of the 100 kilobase pair ovalbumin gene domain. Biochemistry. 1983 Jan 18; 22(2):306-15. PMID: 6297544.
      Citations: 21     Fields:    Translation:AnimalsCells
    196. Anderson JN, Vanderbilt JN, Lawson GM, Tsai MJ, O'Malley BW. Chromatin structure of the ovalbumin gene family in the chicken oviduct. Biochemistry. 1983 Jan 04; 22(1):21-30. PMID: 6299334.
      Citations: 8     Fields:    Translation:AnimalsCells
    197. Stumph WE, Baez M, Lawson GM, Tsai MJ, O'Malley BW. Higher-order structural determinants for expression of the ovalbumin gene family. Ciba Found Symp. 1983; 98:80-95. PMID: 6557011.
      Citations:    Fields:    Translation:AnimalsCells
    198. Ciejek EM, Nordstrom JL, Tsai MJ, O'Malley BW. Ribonucleic acid precursors are associated with the chick oviduct nuclear matrix. Biochemistry. 1982 Sep 28; 21(20):4945-53. PMID: 6182907.
      Citations: 41     Fields:    Translation:AnimalsCells
    199. Lai EC, Roop DR, Tsai MJ, Woo SL, O'Malley BW. Heterogeneous initiation regions for transcription of the chicken ovomucoid gene. Nucleic Acids Res. 1982 Sep 25; 10(18):5553-67. PMID: 6128724; PMCID: PMC320906.
      Citations: 11     Fields:    Translation:AnimalsCells
    200. Zarucki-Schulz T, Tsai SY, Itakura K, Soberon X, Wallace RB, Tsai MJ, Woo SL, O'Malley BW. Point mutagenesis of the ovalbumin gene promoter sequence and its effect on in vitro transcription. J Biol Chem. 1982 Sep 25; 257(18):11070-7. PMID: 6286680.
      Citations: 20     Fields:    Translation:AnimalsCells
    201. Lawson GM, Knoll BJ, March CJ, Woo SL, Tsai MJ, O'Malley BW. Definition of 5' and 3' structural boundaries of the chromatin domain containing the ovalbumin multigene family. J Biol Chem. 1982 Feb 10; 257(3):1501-7. PMID: 6276388.
      Citations: 42     Fields:    Translation:AnimalsCells
    202. Tsai SY, Tsai MJ, Kops LE, Minghetti PP, O'Malley BW. Transcription factors from oviduct and HeLa cells are similar. J Biol Chem. 1981 Dec 25; 256(24):13055-9. PMID: 6895517.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    203. Stumph WE, Kristo P, Tsai MJ, O'Malley BW. A chicken middle-repetitive DNA sequence which shares homology with mammalian ubiquitous repeats. Nucleic Acids Res. 1981 Oct 24; 9(20):5383-97. PMID: 7301590; PMCID: PMC327526.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    204. Roop DR, Kristo P, Stumph WE, Tsai MJ, O'Malley BW. Structure and expression of a chicken gene coding for U1 RNA. Cell. 1981 Mar; 23(3):671-80. PMID: 6164492.
      Citations: 52     Fields:    Translation:Animals
    205. Tsai SY, Tsai MJ, O'Malley BW. Specific 5' flanking sequences are required for faithful initiation of in vitro transcription of the ovalbumin gene. Proc Natl Acad Sci U S A. 1981 Feb; 78(2):879-83. PMID: 6262780; PMCID: PMC319907.
      Citations: 25     Fields:    Translation:HumansCells
    206. O'Malley BW, Woo SL, Tsai MJ. Structure and hormonal regulation of the ovalbumin gene cluster. Curr Top Cell Regul. 1981; 18:437-53. PMID: 6268367.
      Citations:    Fields:    Translation:AnimalsCells
    207. Roop DR, Tsai SY, Tsai MJ, O'Malley BW. Definition of the transcription unit of the natural ovalbumin gene. Prog Clin Biol Res. 1981; 66 Pt B:381-92. PMID: 6273930.
      Citations:    Fields:    Translation:AnimalsCells
    208. Colbert DA, Knoll BJ, Woo SL, Mace ML, Tsai MJ, O'Malley BW. Differential hormonal responsiveness of the ovalbumin gene and its pseudogenes in the chick oviduct. Biochemistry. 1980 Nov 25; 19(24):5586-92. PMID: 6257282.
      Citations: 7     Fields:    Translation:AnimalsCells
    209. Tsai MJ, Ting AC, Nordstrom JL, Zimmer W, O'Malley BW. Processing of high molecular weight ovalbumin and ovomucoid precursor RNAs to messenger RNA. Cell. 1980 Nov; 22(1 Pt 1):219-30. PMID: 7428039.
      Citations: 23     Fields:    Translation:AnimalsCells
    210. Lawson GM, Tsai MJ, O'Malley BW. Deoxyribonuclease I sensitivity of the nontranscribed sequences flanking the 5' and 3' ends of the ovomucoid gene and the ovalbumin and its related X and Y genes in hen oviduct nuclei. Biochemistry. 1980 Sep 16; 19(19):4403-41. PMID: 6250584.
      Citations: 17     Fields:    Translation:AnimalsCells
    211. Tsai SY, Roop DR, Stumph WE, Tsai MJ, O'Malley BW. Evidence that deoxyribonucleic acid sequences flanking the ovalbumin gene are not transcribed. Biochemistry. 1980 Apr 29; 19(9):1755-61. PMID: 6246933.
      Citations: 9     Fields:    Translation:AnimalsCells
    212. Swaneck GE, Tsai MJ, O'Malley BW. Induction of ovalbumin mRNA by estrogen in the chick oviduct. J Steroid Biochem. 1980 Jan; 12:185-91. PMID: 7421207.
      Citations:    Fields:    Translation:AnimalsCells
    213. Roop DR, Tsai MJ, O'Malley BW. Definition of the 5' and 3' ends of transcripts of the ovalbumin gene. Cell. 1980 Jan; 19(1):63-8. PMID: 7357607.
      Citations: 19     Fields:    Translation:Cells
    214. Tsai SY, Tsai MJ, Lin CT, O'Malley BW. Effect of estrogen on ovalbumin gene expression in differentiated nontarget tissues. Biochemistry. 1979 Dec 11; 18(25):5726-31. PMID: 518866.
      Citations: 6     Fields:    Translation:AnimalsCells
    215. Woo SL, Tsai SY, Tsai MJ, Lai EC, Mace ML, O'Malley BW. Cloning and expression of a pseudo-ovalbumin gene. Biochem Biophys Res Commun. 1979 Aug 13; 89(3):997-1005. PMID: 385002.
      Citations:    Fields:    Translation:AnimalsCells
    216. Swaneck GE, Kreuzaler F, Tsai MJ, O'Malley BW. Absence of an obligatory lag period in the induction of ovalbumin mRNA by estrogen. Biochem Biophys Res Commun. 1979 Jun 27; 88(4):1412-8. PMID: 475790.
      Citations: 3     Fields:    Translation:AnimalsCells
    217. Tsai MJ, Tsai SY, O'Malley BW. Distribution of RNA transcripts from structural and intervening sequences of the ovalbumin gene. Science. 1979 Apr 20; 204(4390):314-6. PMID: 432646.
      Citations: 3     Fields:    Translation:AnimalsCells
    218. Nordstrom JL, Roop DR, Tsai MJ, O'Malley BW. Identification of potential ovomucoid mRNA precursors in chick oviduct nuclei. Nature. 1979 Mar 22; 278(5702):328-31. PMID: 423986.
      Citations: 16     Fields:    Translation:AnimalsCells
    219. Swaneck GE, Nordstrom JL, Kreuzaler F, Tsai MJ, O'Malley BW. Effect of estrogen on gene expression in chicken oviduct: evidence for transcriptional control of ovalbumin gene. Proc Natl Acad Sci U S A. 1979 Mar; 76(3):1049-53. PMID: 286292; PMCID: PMC383186.
      Citations: 30     Fields:    Translation:AnimalsCells
    220. Swaneck GE, Tsai SY, Tsai MJ, Nordstrom JL, Roop DR, O'Malley BW. The ovalbumin gene: transcriptional regulation by estrogen. Adv Exp Med Biol. 1979; 117:461-85. PMID: 474290.
      Citations:    Fields:    Translation:AnimalsCells
    221. O'Malley BW, Roop DR, Lai EC, Nordstrom JL, Catterall JF, Swaneck GE, Colbert DA, Tsai MJ, Dugaiczyk A, Woo SL. The ovalbumin gene: organization, structure, transcription, and regulation. Recent Prog Horm Res. 1979; 35:1-46. PMID: 229523.
      Citations: 16     Fields:    Translation:AnimalsCells
    222. Tsai SY, Roop DR, Tsai MJ, Stein JP, Means AR, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. Biochemistry. 1978 Dec 26; 17(26):5773-80. PMID: 728435.
      Citations: 12     Fields:    Translation:AnimalsCells
    223. Tsai MJ, Tsai SY, Chang CW, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. In vitro transcription of the ovalbumin gene. Biochim Biophys Acta. 1978 Dec 21; 521(2):689-707. PMID: 367441.
      Citations: 5     Fields:    Translation:AnimalsCells
    224. Roop DR, Nordstrom JL, Tsai SY, Tsai MJ, O'Malley BW. Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors. Cell. 1978 Oct; 15(2):671-85. PMID: 719758.
      Citations: 58     Fields:    Translation:AnimalsCells
    225. Woo SL, Dugaiczyk A, Tsai MJ, Lai EC, Catterall JF, O'Malley BW. The ovalbumin gene: cloning of the natural gene. Proc Natl Acad Sci U S A. 1978 Aug; 75(8):3688-92. PMID: 358194; PMCID: PMC392851.
      Citations: 15     Fields:    Translation:AnimalsCells
    226. O'Malley BW, Tsai MJ, Tsai SY, Towle HC. Regulation of gene expression in chick oviduct. Cold Spring Harb Symp Quant Biol. 1978; 42 Pt 2:605-15. PMID: 354851.
      Citations: 4     Fields:    Translation:AnimalsCells
    227. Towle HC, Tsai MJ, Tsai SY, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. J Biol Chem. 1977 Apr 10; 252(7):2396-404. PMID: 321457.
      Citations: 5     Fields:    Translation:AnimalsCells
    228. Tsai SY, Tsai MJ, Harris SE, O'Malley BW. Effects of estrogen on gene expression in the chick oviduct. Control of ovalbumin gene expression by non-histone proteins. J Biol Chem. 1976 Oct 25; 251(20):6475-8. PMID: 977585.
      Citations: 2     Fields:    Translation:AnimalsCells
    229. Tsai MJ, Tsai SY, Towle HC, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Studies on the initiation of RNA synthesis on chromatin in vitro. J Biol Chem. 1976 Sep 25; 251(18):5565-74. PMID: 786984.
      Citations: 2     Fields:    Translation:AnimalsCells
    230. Tsai SY, Harris SE, Tsai MJ, O'Malley BW. Effects of estrogen on gene expression in chick oviduct. The role of chromatin proteins in regulating transcription of the ovalbumin gene. J Biol Chem. 1976 Aug 10; 251(15):4713-21. PMID: 947905.
      Citations: 5     Fields:    Translation:AnimalsCells
    231. Tsai MJ, Towle TC, Harris SE, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. J Biol Chem. 1976 Apr 10; 251(7):1960-8. PMID: 773931.
      Citations: 12     Fields:    Translation:AnimalsCells
    232. Hirose M, Tsai MJ, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Kinetics of initiation of in vitro transcription on chromatin. J Biol Chem. 1976 Feb 25; 251(4):1137-46. PMID: 765337.
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    233. Kalimi M, Tsai SY, Tsai MJ, Clark JH, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. Correlation between nuclear-bound estrogen receptor and chromatin initiation site for transcription. J Biol Chem. 1976 Jan 25; 251(2):516-23. PMID: 173720.
      Citations: 10     Fields:    Translation:AnimalsCells
    234. Harris SE, Schwartz RJ, Tsai MJ, O'Malley BW, Roy AK. Effect of estrogen on gene expression in the chick oviduct. In vitro transcription of the ovalbumin gene in chromatin. J Biol Chem. 1976 Jan 25; 251(2):524-9. PMID: 1245487.
      Citations: 12     Fields:    Translation:AnimalsCells
    235. Towle HC, Tsai MJ, Hirose M, Tsai SY, Schwartz RJ, Parker MG, O'Malley BW. Regulation of transcription of the eucaryotic genome. Symp Soc Dev Biol. 1976; (34):107-36. PMID: 798339.
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    236. Garcia HD, Tsai MJ, Saunders GF. Template properties of human DNA-dependent RNA polymerase II. Med Pediatr Oncol. 1976; 2(3):243-52. PMID: 790145.
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    237. Tsai SY, Tsai MJ, Schwartz R, Kalimi M, Clark JH, O'Malley BW. Effects of estrogen on gene expression in chick oviduct: nuclear receptor levels and initiation of transcription. Proc Natl Acad Sci U S A. 1975 Nov; 72(11):4228-32. PMID: 172899; PMCID: PMC388693.
      Citations: 9     Fields:    Translation:AnimalsCells
    238. Schwartz RJ, Tsai SY, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. V. Changes in the number of RNA polymerase binding and initiation sites in chromatin. J Biol Chem. 1975 Jul 10; 250(13):5175-82. PMID: 1097440.
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    239. Tsai MJ, Saunders GF. Isolation and characterization of human DNA-dependent RNA polymerase. Biochim Biophys Acta. 1974 Sep 27; 366(1):61-9. PMID: 4472531.
      Citations:    Fields:    Translation:HumansAnimalsCells
    240. Tsai MJ, Saunders GF. Action of rifamycin derivatives on RNA polymerase of human leukemic lymphocytes. Proc Natl Acad Sci U S A. 1973 Jul; 70(7):2072-6. PMID: 4516206; PMCID: PMC433668.
      Citations: 5     Fields:    Translation:HumansCells
    241. Tsai MJ, Saunders GF. Transcription of chromatin by human RNA polymerase. Biochem Biophys Res Commun. 1973 Apr 02; 51(3):756-65. PMID: 4574236.
      Citations: 6     Fields:    Translation:HumansCells
    242. Michaelis G, Douglass S, Tsai MJ, Burchiel K, Criddle RS. In vitro transcription of mitochondrial deoxyribonucleic acid from yeast. Biochemistry. 1972 May 23; 11(11):2026-36. PMID: 4554895.
      Citations: 7     Fields:    Translation:AnimalsCells
    243. Michaelis G, Douglass S, Tsai MJ, Criddle RS. Mitochondrial DNA and suppressiveness of petite mutants in Saccharomyces cerevisiae. Biochem Genet. 1971 Oct; 5(5):487-95. PMID: 5520795.
      Citations: 24     Fields:    Translation:AnimalsCells
    244. Tsai MJ, Michaelis G, Criddle RS. DNA-dependent RNA polymerase from yeast mitochondria. Proc Natl Acad Sci U S A. 1971 Feb; 68(2):473-7. PMID: 5277104; PMCID: PMC388963.
      Citations: 17     Fields:    Translation:Cells
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