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KARIM A. ALKADHI

TitleProfessor
InstitutionUniversity of Houston College of Pharmacy
DepartmentPharmacological & Pharmaceutical Sciences
Address521E Science and Research Building 2
Houston TX 77204-5037
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    1. Alkadhi KA, Alhaider IA. Caffeine and REM sleep deprivation: Effect on basal levels of signaling molecules in area CA1. Mol Cell Neurosci. 2016 Mar; 71:125-31. PMID: 26767416.
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    2. Dao AT, Zagaar MA, Levine AT, Alkadhi KA. Comparison of the Effect of Exercise on Late-Phase LTP of the Dentate Gyrus and CA1 of Alzheimer's Disease Model. Mol Neurobiol. 2016 Dec; 53(10):6859-6868. PMID: 26660327.
      View in: PubMed
    3. Alhaider IA, Alkadhi KA. Caffeine treatment prevents rapid eye movement sleep deprivation-induced impairment of late-phase long-term potentiation in the dentate gyrus. Eur J Neurosci. 2015 Nov; 42(10):2843-50. PMID: 26449851.
      View in: PubMed
    4. Zagaar MA, Dao AT, Alhaider IA, Alkadhi KA. Prevention by Regular Exercise of Acute Sleep Deprivation-Induced Impairment of Late Phase LTP and Related Signaling Molecules in the Dentate Gyrus. Mol Neurobiol. 2016 Jul; 53(5):2900-10. PMID: 25902862.
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    5. Dao AT, Zagaar MA, Alkadhi KA. Moderate Treadmill Exercise Protects Synaptic Plasticity of the Dentate Gyrus and Related Signaling Cascade in a Rat Model of Alzheimer's Disease. Mol Neurobiol. 2015 Dec; 52(3):1067-76. PMID: 25288155.
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    6. Alkadhi KA, Tran TT. Chronic psychosocial stress impairs early LTP but not late LTP in the dentate gyrus of at-risk rat model of Alzheimer's disease. Brain Res. 2014 Nov 7; 1588:150-8. PMID: 25219483.
      View in: PubMed
    7. Alkadhi KA, Tran TT. Chronic Stress Decreases Basal Levels of Memory-Related Signaling Molecules in Area CA1 of At-Risk (Subclinical) Model of Alzheimer's Disease. Mol Neurobiol. 2015 Aug; 52(1):93-100. PMID: 25112676.
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    8. Patki G, Li L, Allam F, Solanki N, Dao AT, Alkadhi K, Salim S. Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder. Physiol Behav. 2014 May 10; 130:47-53. PMID: 24657739; PMCID: PMC4318362.
    9. Alzoubi KH, Alkadhi KA. Chronic nicotine treatment reverses hypothyroidism-induced impairment of L-LTP induction phase: critical role of CREB. Mol Neurobiol. 2014 Jun; 49(3):1245-55. PMID: 24277525.
      View in: PubMed
    10. Dao AT, Zagaar MA, Salim S, Eriksen JL, Alkadhi KA. Regular exercise prevents non-cognitive disturbances in a rat model of Alzheimer's disease. Int J Neuropsychopharmacol. 2014 Apr; 17(4):593-602. PMID: 24229510; PMCID: PMC4097602.
    11. Alzoubi KH, Alkadhi KA. Levothyroxin replacement therapy restores hypothyroidism induced impairment of L-LTP induction: critical role of CREB. Brain Res Bull. 2014 Jan; 100:29-37. PMID: 24216002.
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    12. Patki G, Allam FH, Atrooz F, Dao AT, Solanki N, Chugh G, Asghar M, Jafri F, Bohat R, Alkadhi KA, Salim S. Grape powder intake prevents ovariectomy-induced anxiety-like behavior, memory impairment and high blood pressure in female Wistar rats. PLoS One. 2013; 8(9):e74522. PMID: 24040270; PMCID: PMC3767647.
    13. Zagaar M, Dao A, Alhaider I, Alkadhi K. Regular treadmill exercise prevents sleep deprivation-induced disruption of synaptic plasticity and associated signaling cascade in the dentate gyrus. Mol Cell Neurosci. 2013 Sep; 56:375-83. PMID: 23911794.
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    14. Chugh G, Asghar M, Patki G, Bohat R, Jafri F, Allam F, Dao AT, Mowrey C, Alkadhi K, Salim S. A high-salt diet further impairs age-associated declines in cognitive, behavioral, and cardiovascular functions in male Fischer brown Norway rats. J Nutr. 2013 Sep; 143(9):1406-13. PMID: 23864508; PMCID: PMC3743272.
    15. Alzoubi KH, Khabour OF, Alhaidar IA, Aleisa AM, Alkadhi KA. Diabetes impairs synaptic plasticity in the superior cervical ganglion: possible role for BDNF and oxidative stress. J Mol Neurosci. 2013 Nov; 51(3):763-70. PMID: 23832486.
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    16. Dao AT, Zagaar MA, Levine AT, Salim S, Eriksen JL, Alkadhi KA. Treadmill exercise prevents learning and memory impairment in Alzheimer's disease-like pathology. Curr Alzheimer Res. 2013 Jun; 10(5):507-15. PMID: 23627709; PMCID: PMC4004077.
    17. Alkadhi K, Zagaar M, Alhaider I, Salim S, Aleisa A. Neurobiological consequences of sleep deprivation. Curr Neuropharmacol. 2013 May; 11(3):231-49. PMID: 24179461; PMCID: PMC3648777.
    18. Zagaar M, Dao A, Levine A, Alhaider I, Alkadhi K. Regular exercise prevents sleep deprivation associated impairment of long-term memory and synaptic plasticity in the CA1 area of the hippocampus. Sleep. 2013 May; 36(5):751-61. PMID: 23633758; PMCID: PMC3624830.
    19. Allam F, Dao AT, Chugh G, Bohat R, Jafri F, Patki G, Mowrey C, Asghar M, Alkadhi KA, Salim S. Grape powder supplementation prevents oxidative stress-induced anxiety-like behavior, memory impairment, and high blood pressure in rats. J Nutr. 2013 Jun; 143(6):835-42. PMID: 23596160; PMCID: PMC3652881.
    20. Alzoubi KH, Srivareerat M, Tran TT, Alkadhi KA. Role of ?7- and ?4?2-nAChRs in the neuroprotective effect of nicotine in stress-induced impairment of hippocampus-dependent memory. Int J Neuropsychopharmacol. 2013 Jun; 16(5):1105-13. PMID: 23067572.
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    21. Alzoubi KH, Abdul-Razzak KK, Khabour OF, Al-Tuweiq GM, Alzubi MA, Alkadhi KA. Caffeine prevents cognitive impairment induced by chronic psychosocial stress and/or high fat-high carbohydrate diet. Behav Brain Res. 2013 Jan 15; 237:7-14. PMID: 23000531.
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    22. Alzoubi KH, Srivareerat M, Aleisa AM, Alkadhi KA. Chronic caffeine treatment prevents stress-induced LTP impairment: the critical role of phosphorylated CaMKII and BDNF. J Mol Neurosci. 2013 Jan; 49(1):11-20. PMID: 22706686.
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    23. Zagaar M, Alhaider I, Dao A, Levine A, Alkarawi A, Alzubaidy M, Alkadhi K. The beneficial effects of regular exercise on cognition in REM sleep deprivation: behavioral, electrophysiological and molecular evidence. Neurobiol Dis. 2012 Mar; 45(3):1153-62. PMID: 22227452.
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    24. Alkadhi KA. Chronic stress and Alzheimer's disease-like pathogenesis in a rat model: prevention by nicotine. Curr Neuropharmacol. 2011 Dec; 9(4):587-97. PMID: 22654719; PMCID: PMC3263455.
    25. Alkadhi K, Eriksen J. The complex and multifactorial nature of Alzheimer's disease. Curr Neuropharmacol. 2011 Dec; 9(4):586. PMID: 22654718; PMCID: PMC3263454.
    26. Alkadhi KA, Alzoubi KH, Srivareerat M, Tran TT. Chronic psychosocial stress exacerbates impairment of synaptic plasticity in ?-amyloid rat model of Alzheimer's disease: prevention by nicotine. Curr Alzheimer Res. 2011 Nov; 8(7):718-31. PMID: 21453245.
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    27. Tran TT, Srivareerat M, Alhaider IA, Alkadhi KA. Chronic psychosocial stress enhances long-term depression in a subthreshold amyloid-beta rat model of Alzheimer's disease. J Neurochem. 2011 Oct; 119(2):408-16. PMID: 21854392.
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    28. Aleisa AM, Alzoubi KH, Alkadhi KA. Post-learning REM sleep deprivation impairs long-term memory: reversal by acute nicotine treatment. Neurosci Lett. 2011 Jul 15; 499(1):28-31. PMID: 21624432.
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    29. Vollert C, Zagaar M, Hovatta I, Taneja M, Vu A, Dao A, Levine A, Alkadhi K, Salim S. Exercise prevents sleep deprivation-associated anxiety-like behavior in rats: potential role of oxidative stress mechanisms. Behav Brain Res. 2011 Oct 31; 224(2):233-40. PMID: 21621560.
      View in: PubMed
    30. Zoladz PR, Park CR, Halonen JD, Salim S, Alzoubi KH, Srivareerat M, Fleshner M, Alkadhi KA, Diamond DM. Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia. Hippocampus. 2012 Mar; 22(3):577-89. PMID: 21538655.
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    31. Alkadhi KA, Alzoubi KH, Srivareerat M, Tran TT. Elevation of BACE in an A? rat model of Alzheimer's disease: exacerbation by chronic stress and prevention by nicotine. Int J Neuropsychopharmacol. 2012 Mar; 15(2):223-33. PMID: 21356140.
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    32. Alkadhi KA, Srivareerat M, Tran TT. Intensification of long-term memory deficit by chronic stress and prevention by nicotine in a rat model of Alzheimer's disease. Mol Cell Neurosci. 2010 Nov; 45(3):289-96. PMID: 20624465.
      View in: PubMed
    33. Aleisa AM, Helal G, Alhaider IA, Alzoubi KH, Srivareerat M, Tran TT, Al-Rejaie SS, Alkadhi KA. Acute nicotine treatment prevents REM sleep deprivation-induced learning and memory impairment in rat. Hippocampus. 2011 Aug; 21(8):899-909. PMID: 20865738.
      View in: PubMed
    34. Tran TT, Srivareerat M, Alkadhi KA. Chronic psychosocial stress accelerates impairment of long-term memory and late-phase long-term potentiation in an at-risk model of Alzheimer's disease. Hippocampus. 2011 Jul; 21(7):724-32. PMID: 20865724.
      View in: PubMed
    35. Alhaider IA, Aleisa AM, Tran TT, Alkadhi KA. Caffeine prevents sleep loss-induced deficits in long-term potentiation and related signaling molecules in the dentate gyrus. Eur J Neurosci. 2010 Apr; 31(8):1368-76. PMID: 20384774.
      View in: PubMed
    36. Alhaider IA, Aleisa AM, Tran TT, Alzoubi KH, Alkadhi KA. Chronic caffeine treatment prevents sleep deprivation-induced impairment of cognitive function and synaptic plasticity. Sleep. 2010 Apr; 33(4):437-44. PMID: 20394312; PMCID: PMC2849782.
    37. Tran TT, Srivareerat M, Alkadhi KA. Chronic psychosocial stress triggers cognitive impairment in a novel at-risk model of Alzheimer's disease. Neurobiol Dis. 2010 Mar; 37(3):756-63. PMID: 20044001.
      View in: PubMed
    38. Alzoubi KH, Abdul-Razzak KK, Khabour OF, Al-Tuweiq GM, Alzubi MA, Alkadhi KA. Adverse effect of combination of chronic psychosocial stress and high fat diet on hippocampus-dependent memory in rats. Behav Brain Res. 2009 Dec 1; 204(1):117-23. PMID: 19482049.
      View in: PubMed
    39. Srivareerat M, Tran TT, Salim S, Aleisa AM, Alkadhi KA. Chronic nicotine restores normal A? levels and prevents short-term memory and E-LTP impairment in A? rat model of Alzheimer's disease. Neurobiol Aging. 2011 May; 32(5):834-44. PMID: 19464074.
      View in: PubMed
    40. Alzoubi KH, Gerges NZ, Aleisa AM, Alkadhi KA. Levothyroxin restores hypothyroidism-induced impairment of hippocampus-dependent learning and memory: Behavioral, electrophysiological, and molecular studies. Hippocampus. 2009 Jan; 19(1):66-78. PMID: 18680156.
      View in: PubMed
    41. Alzoubi KH, Alkadhi KA. Calmodulin and guanylyl cyclase inhibitors block the in vivo expression of gLTP in sympathetic ganglia from chronically stressed rats. Neurosci Res. 2009 Feb; 63(2):95-9. PMID: 19038294.
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    42. Srivareerat M, Tran TT, Alzoubi KH, Alkadhi KA. Chronic psychosocial stress exacerbates impairment of cognition and long-term potentiation in beta-amyloid rat model of Alzheimer's disease. Biol Psychiatry. 2009 Jun 1; 65(11):918-26. PMID: 18849021.
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    43. Alkadhi KA. Rhythmic discharge induced by temperature variation and drugs in isolated sympathetic ganglia. Clin Exp Hypertens. 2008 Oct; 30(7):497-510. PMID: 18855254.
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    44. Alkadhi KA, Al-Hijailan RS, Alzoubi KH. Long-term depression in the superior cervical ganglion of the rat. Brain Res. 2008 Oct 9; 1234:25-31. PMID: 18718451.
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    45. Alzoubi KH, Aleisa AM, Alkadhi KA. In vivo expression of ganglionic long-term potentiation in superior cervical ganglia from hypertensive aged rats. Neurobiol Aging. 2010 May; 31(5):805-12. PMID: 18649973.
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    46. Alzoubi KH, Aleisa AM, Alkadhi KA. Effect of chronic stress or nicotine on hypothyroidism-induced enhancement of LTD: electrophysiological and molecular studies. Neurobiol Dis. 2008 Oct; 32(1):81-7. PMID: 18638553.
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    47. Alzoubi KH, Aleisa AM, Alkadhi KA. Expression of gLTP in sympathetic ganglia of obese Zucker rats in vivo: molecular evidence. J Mol Neurosci. 2008 Jul; 35(3):297-306. PMID: 18563301.
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    48. Alzoubi KH, Aleisa AM, Alkadhi KA. Expression of gLTP in sympathetic ganglia from stress-hypertensive rats: molecular evidence. J Mol Neurosci. 2008 Jun; 35(2):201-9. PMID: 18386186.
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    49. Alzoubi KH, Aleisa AM, Alkadhi KA. The sliding threshold of modification hypothesis: application to the effect of hypothyroidism or chronic psychosocial stress and nicotine on synaptic plasticity. Neurosci Lett. 2008 Jan 17; 430(3):203-6. PMID: 18063475.
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    50. Alzoubi KH, Aleisa AM, Alkadhi KA. Adult-onset hypothyroidism facilitates and enhances LTD: reversal by chronic nicotine treatment. Neurobiol Dis. 2007 Apr; 26(1):264-72. PMID: 17331737.
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    51. Alzoubi KH, Aleisa AM, Alkadhi KA. Nicotine prevents disruption of the late phase LTP-related molecular cascade in adult-onset hypothyroidism. Hippocampus. 2007; 17(8):654-64. PMID: 17523180.
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    52. Alzoubi KH, Aleisa AM, Gerges NZ, Alkadhi KA. Nicotine reverses adult-onset hypothyroidism-induced impairment of learning and memory: Behavioral and electrophysiological studies. J Neurosci Res. 2006 Oct; 84(5):944-53. PMID: 16902999.
      View in: PubMed
    53. Alzoubi KH, Alkadhi KA. A critical role of CREB in the impairment of late-phase LTP by adult onset hypothyroidism. Exp Neurol. 2007 Jan; 203(1):63-71. PMID: 16952356.
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    54. Aleisa AM, Alzoubi KH, Alkadhi KA. Chronic but not acute nicotine treatment reverses stress-induced impairment of LTP in anesthetized rats. Brain Res. 2006 Jun 30; 1097(1):78-84. PMID: 16725127.
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    55. Aleisa AM, Alzoubi KH, Gerges NZ, Alkadhi KA. Chronic psychosocial stress-induced impairment of hippocampal LTP: possible role of BDNF. Neurobiol Dis. 2006 Jun; 22(3):453-62. PMID: 16530419.
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    56. Aleisa AM, Alzoubi KH, Alkadhi KA. Nicotine prevents stress-induced enhancement of long-term depression in hippocampal area CA1: electrophysiological and molecular studies. J Neurosci Res. 2006 Feb 1; 83(2):309-17. PMID: 16307449.
      View in: PubMed
    57. Alzoubi KH, Aleisa AM, Alkadhi KA. Molecular studies on the protective effect of nicotine in adult-onset hypothyroidism-induced impairment of long-term potentiation. Hippocampus. 2006; 16(10):861-74. PMID: 16897721.
      View in: PubMed
    58. Alzoubi KH, Gerges NZ, Alkadhi KA. Levothyroxin restores hypothyroidism-induced impairment of LTP of hippocampal CA1: electrophysiological and molecular studies. Exp Neurol. 2005 Oct; 195(2):330-41. PMID: 16004982.
      View in: PubMed
    59. Aleisa AM, Alzoubi KH, Gerges NZ, Alkadhi KA. Nicotine blocks stress-induced impairment of spatial memory and long-term potentiation of the hippocampal CA1 region. Int J Neuropsychopharmacol. 2006 Aug; 9(4):417-26. PMID: 16316479.
      View in: PubMed
    60. Alkadhi KA, Alzoubi KH, Aleisa AM, Tanner FL, Nimer AS. Psychosocial stress-induced hypertension results from in vivo expression of long-term potentiation in rat sympathetic ganglia. Neurobiol Dis. 2005 Dec; 20(3):849-57. PMID: 16005635.
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    61. Gerges NZ, Alzoubi KH, Alkadhi KA. Role of phosphorylated CaMKII and calcineurin in the differential effect of hypothyroidism on LTP of CA1 and dentate gyrus. Hippocampus. 2005; 15(4):480-90. PMID: 15714506.
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    62. Alzoubi KH, Aleisa AM, Alkadhi KA. Impairment of long-term potentiation in the CA1, but not dentate gyrus, of the hippocampus in Obese Zucker rats: role of calcineurin and phosphorylated CaMKII. J Mol Neurosci. 2005; 27(3):337-46. PMID: 16280604.
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    63. Gerges NZ, Alzoubi KH, Park CR, Diamond DM, Alkadhi KA. Adverse effect of the combination of hypothyroidism and chronic psychosocial stress on hippocampus-dependent memory in rats. Behav Brain Res. 2004 Nov 5; 155(1):77-84. PMID: 15325781.
      View in: PubMed
    64. Alzoubi KH, Bedawi AS, Aleisa AM, Alkadhi KA. Hypothyroidism impairs long-term potentiation in sympathetic ganglia: electrophysiologic and molecular studies. J Neurosci Res. 2004 Nov 1; 78(3):393-402. PMID: 15389831.
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    65. Otoom SA, Alkadhi KA, Daoud AS. Guanosine 3`,5`-monophosphate is not a marker of the proepileptic activity of valproic acid in hippocampal brain tissues. Neurosciences (Riyadh). 2004 Jul; 9(3):176-9. PMID: 23377423.
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    66. Gerges NZ, Aleisa AM, Schwarz LA, Alkadhi KA. Reduced basal CaMKII levels in hippocampal CA1 region: possible cause of stress-induced impairment of LTP in chronically stressed rats. Hippocampus. 2004; 14(3):402-10. PMID: 15132438.
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    67. Gerges NZ, Alkadhi KA. Hypothyroidism impairs late LTP in CA1 region but not in dentate gyrus of the intact rat hippocampus: MAPK involvement. Hippocampus. 2004; 14(1):40-5. PMID: 15058481.
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    68. Gerges NZ, Aleisa AM, Alkadhi KA. Impaired long-term potentiation in obese zucker rats: possible involvement of presynaptic mechanism. Neuroscience. 2003; 120(2):535-9. PMID: 12890522.
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    69. Gerges NZ, Aleisa AM, Schwarz LA, Alkadhi KA. Chronic psychosocial stress decreases calcineurin in the dentate gyrus: a possible mechanism for preservation of early ltp. Neuroscience. 2003; 117(4):869-74. PMID: 12654339.
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    70. Gerges NZ, Aleisa AM, Alhaider AA, Alkadhi KA. Reduction of elevated arterial blood pressure in obese Zucker rats by inhibition of ganglionic long-term potentiation. Neuropharmacology. 2002 Dec; 43(7):1070-6. PMID: 12504912.
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    71. Gerges NZ, Stringer JL, Alkadhi KA. Combination of hypothyroidism and stress abolishes early LTP in the CA1 but not dentate gyrus of hippocampus of adult rats. Brain Res. 2001 Dec 20; 922(2):250-60. PMID: 11743957.
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    72. Alkadhi KA, Otoom SA, Tanner FL, Sockwell D, Hogan YH. Inhibition of ganglionic long-term potentiation decreases blood pressure in spontaneously hypertensive rats. Exp Biol Med (Maywood). 2001 Dec; 226(11):1024-30. PMID: 11743138.
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    73. Alkadhi KA, Al-Hijailan RS, Malik K, Hogan YH. Retrograde carbon monoxide is required for induction of long-term potentiation in rat superior cervical ganglion. J Neurosci. 2001 May 15; 21(10):3515-20. PMID: 11331380.
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    74. Otoom SA, Alkadhi KA. Action of carbamazepine on epileptiform activity of the verartidine model in CA1 neurons. Brain Res. 2000 Dec 8; 885(2):289-94. PMID: 11102583.
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    75. Otoom SA, Alkadhi KA. Epileptiform activity of veratridine model in rat brain slices: effects of antiepileptic drugs. Epilepsy Res. 2000 Feb; 38(2-3):161-70. PMID: 10642044.
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    76. Otoom SA, Alkadhi KA. Valproic acid intensifies epileptiform activity in the hippocampal pyramidal neurons. Neurosci Res. 1999 Dec 30; 35(4):299-307. PMID: 10617321.
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    77. Altememi GF, Alkadhi KA. Nitric oxide is required for the maintenance but not initiation of ganglionic long-term potentiation. Neuroscience. 1999; 94(3):897-902. PMID: 10579581.
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    78. Hogan YH, Hawkins R, Alkadhi KA. Adenosine A1 receptor activation inhibits LTP in sympathetic ganglia. Brain Res. 1998 Oct 5; 807(1-2):19-28. PMID: 9756986.
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    79. Otoom S, Tian LM, Alkadhi KA. Veratridine-treated brain slices: a cellular model for epileptiform activity. Brain Res. 1998 Apr 6; 789(1):150-6. PMID: 9602103.
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    80. Hogan YH, Florent G, Hussain T, Alkadhi KA. Cyclic AMP antagonizes adenosine-induced inhibition of ganglionic transmission. Brain Res. 1998 Mar 23; 787(2):242-7. PMID: 9518635.
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    81. Salgado-Commissariat D, Alkadhi KA. Serotonin inhibits epileptiform discharge by activation of 5-HT1A receptors in CA1 pyramidal neurons. Neuropharmacology. 1997 Nov-Dec; 36(11-12):1705-12. PMID: 9517442.
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    82. Alkadhi KA, Altememi GF. Nitric oxide mediates long-term potentiation in rat superior cervical ganglion. Brain Res. 1997 Apr 11; 753(2):315-7. PMID: 9125417.
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    83. Salgado-Commissariat D, Alkadhi KA. Effects of serotonin on induced epileptiform activity in CA1 pyramidal neurons of genetically epilepsy prone rats. Brain Res. 1996 Dec 16; 743(1-2):212-6. PMID: 9017248.
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    84. Alkadhi KA, Salgado-Commissariat D, Hogan YH, Akpaudo SB. Induction and maintenance of ganglionic long-term potentiation require activation of 5-hydroxytryptamine (5-HT3) receptors. J Physiol. 1996 Oct 15; 496 ( Pt 2):479-89. PMID: 8910231; PMCID: PMC1160892.
    85. Alkadhi KA, Tian LM. Veratridine-enhanced persistent sodium current induces bursting in CA1 pyramidal neurons. Neuroscience. 1996 Apr; 71(3):625-32. PMID: 8867036.
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    86. Tian LM, Otoom S, Alkadhi KA. Endogenous bursting due to altered sodium channel function in rat hippocampal CA1 neurons. Brain Res. 1995 May 22; 680(1-2):164-72. PMID: 7663974.
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    87. Salgado D, Alkadhi KA. Inhibition of epileptiform activity by serotonin in rat CA1 neurons. Brain Res. 1995 Jan 16; 669(2):176-82. PMID: 7712172.
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    88. Tian LM, Alkadhi KA. Valproic acid inhibits the depolarizing rectification in neurons of rat amygdala. Neuropharmacology. 1994 Oct; 33(10):1131-8. PMID: 7862248.
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    89. Salgado D, Shek EW, Alkadhi KA. Effects of ATP-sensitive K(+)-channel activators on transmitter release parameters at the frog neuromuscular junction. Brain Res. 1993 Apr 23; 609(1-2):307-12. PMID: 8099524.
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    90. Alkadhi KA, Salgado D, Davis CA, Udofia EI. Effects of gamma-aminobutyric acid on the compound action potential of the rat superior cervical ganglion. Arch Int Pharmacodyn Ther. 1993 Mar-Apr; 322:66-79. PMID: 8215719.
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    91. Alkadhi KA, Hogan YH. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydroxypyridine (MPTP) on ganglionic transmission. J Auton Pharmacol. 1992 Feb; 12(1):15-23. PMID: 1313036.
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    92. Alkadhi KA, Simples JE. Effects of inorganic potassium channel blockers on calcium requirement of transmission in a sympathetic ganglion. J Auton Nerv Syst. 1991 Jun 15; 34(2-3):221-9. PMID: 1655860.
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    93. Alkadhi KA, Bassey EI, Hogan YH. A comparative study of the actions of histamine H2 receptor antagonists on transmission in the isolated superior cervical ganglion of the rat. Neuropharmacology. 1990 Mar; 29(3):285-90. PMID: 1970132.
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    94. Alkadhi KA. Giant miniature end-plate potentials at the untreated and emetine-treated frog neuromuscular junction. J Physiol. 1989 May; 412:475-91. PMID: 2600842; PMCID: PMC1190587.
    95. Alkadhi KA, Hogan YH. Effect of calcium on synaptic facilitation by potassium channel blockers in superior cervical ganglion of rat. Neuropharmacology. 1989 Jan; 28(1):75-81. PMID: 2538769.
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    96. Alkadhi KA. Emetine increases giant miniature endplate potential population at the frog neuromuscular junction. Brain Res. 1988 May 3; 447(2):293-8. PMID: 3260532.
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    97. Alkadhi KA, Sabouni MH, Hogan YH, Jandhyala BS. Effects of felodipine and verapamil on transmission in the isolated superior cervical ganglion of the rat. Arch Int Pharmacodyn Ther. 1987 Jul; 288(1):50-8. PMID: 2821941.
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    98. Alkadhi KA. Effects of emetine and dehydroemetine at the frog neuromuscular junction. Eur J Pharmacol. 1987 Jun 19; 138(2):257-64. PMID: 2887439.
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    99. Sabouni MH, Alkadhi KA, Lokhandwala MF. Effect of dopamine receptor activation on ganglionic transmission and cyclic AMP levels in the stellate ganglia and renal arteries of the dog. J Pharmacol Exp Ther. 1987 Jan; 240(1):93-8. PMID: 2879905.
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    100. Alkadhi KA, Sabouni MH, Ansari AF, Lokhandwala MF. Activation of DA1 receptors by dopamine or fenoldopam increases cyclic AMP levels in the renal artery but not in the superior cervical ganglion of the rat. J Pharmacol Exp Ther. 1986 Aug; 238(2):547-53. PMID: 2874213.
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    101. Cates LA, Li VS, Basrur JP, Alkadhi KA. 2,2'-Phthaloyl-,2,2'-isophthaloyl-, and 2,2'-terephthaloylbis[1,1,1-trimethylhydrazinium] dihydroxide, bis(inner salts): synthesis, partition coefficients, toxicity and effect on ganglionic transmission. J Pharm Sci. 1986 Apr; 75(4):407-9. PMID: 2873233.
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    102. Alkadhi KA. Endplate channel actions of a hemicholinium-3 analog, DMAE. Naunyn Schmiedebergs Arch Pharmacol. 1986 Mar; 332(3):230-5. PMID: 3012371.
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    103. Sabouni MH, Alkadhi KA, Lokhandwala MF. Pharmacological characterization of dopamine receptors in the stellate ganglia with selective DA1 and DA2 receptor agonists and antagonists. J Pharmacol Exp Ther. 1986 Jan; 236(1):65-70. PMID: 2867216.
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    104. Lokhandwala MF, Watkins HO, Sabouni MH, Alkadhi KA. Pharmacological analysis of the actions of SKF 82526 on cardiovascular dopamine receptors. J Pharmacol Exp Ther. 1985 Aug; 234(2):337-44. PMID: 2862275.
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    105. Cates LA, Li VS, Saddawi BH, Alkadhi KA. Phosphorus-nitrogen compounds. 26. Phosphaminimides. 2. 2,2'-Phosphinylidenebis(1,1,1-trimethylhydrazinium) iodide inner salts as agents affecting ganglionic transmission. J Med Chem. 1985 May; 28(5):595-7. PMID: 2859370.
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    106. Alkadhi KA, Brown TR, Sabouni MH. Inhibitory effect of adenosine on transmission in sympathetic ganglia. Naunyn Schmiedebergs Arch Pharmacol. 1984 Nov; 328(1):16-9. PMID: 6096724.
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    107. Alkadhi KA, Banks FW. Pre- and postsynaptic actions of valproic acid at the frog neuromuscular junction. Brain Res. 1984 Jul 23; 306(1-2):388-90. PMID: 6087980.
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    108. Taha MN, Alkadhi KA. Effects of Methylmercuric chloride on sympathetic preganglionic nerves. Arch Toxicol. 1982 Jul; 50(2):141-7. PMID: 7125908.
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    109. Volle RL, Alkadhi KA, Branisteanu DD, Reynolds LS, Epstein PM, Smilowitz H, Lambert JJ, Henderson EG. Ketamine and ditran block end-plate ion conductance and [3H]phencyclidine binding to electric organ membrane. J Pharmacol Exp Ther. 1982 Jun; 221(3):570-6. PMID: 6123584.
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    110. Volle RL, Quenzer LF, Patterson BA, Alkadhi KA, Henderson EG. Cyclic guanosine 3':5'-monophosphate accumulation and 45Ca-uptake by rat superior cervical ganglia during preganglionic stimulation. J Pharmacol Exp Ther. 1981 Nov; 219(2):338-43. PMID: 6116799.
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    111. Alkadhi K, Branisteanu DD, Henderson EG, Lambert JJ, Volle RL. Effects of McN-A-343, a cholinomimetic drug, on endplate currents in the frog. Naunyn Schmiedebergs Arch Pharmacol. 1980 Jun; 312(2):117-21. PMID: 6157110.
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    112. Quenzer L, Yahn D, Alkadhi K, Volle RL. Transmission blockade and stimulation of ganglionic adenylate cyclase by catecholamines. J Pharmacol Exp Ther. 1979 Jan; 208(1):31-6. PMID: 215748.
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    113. Alkadhi KA, McIsaac RJ. Ganglion blocking effects of streptomycin. Arch Int Pharmacodyn Ther. 1978 Mar; 232(1):58-67. PMID: 27152.
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    114. Alkadhi K, Volle RL. Transmitter mobilization at the frog neuromuscular junction. Arch Int Pharmacodyn Ther. 1977 Oct; 229(2):261-75. PMID: 23083.
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    115. Alkadhi KA, McIsaac RJ. Differential blockade of ganglionic transmission by extract from venom gland of black widow spider (Latrodectus mactans). Toxicon. 1974 Dec; 12(6):643-8. PMID: 4156433.
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    116. Alkadhi KA, McIsaac RJ. Effect of preganglionic nerve stimulation on sensitivity of the superior cervical ganglion to nicotinic blocking agents. Br J Pharmacol. 1974 Aug; 51(4):533-9. PMID: 4155976; PMCID: PMC1778062.
    117. Alkadhi KA, McIsaac RJ. Non-nicotinic transmission during ganglionic block with chlorisondamine and nicotine. Eur J Pharmacol. 1973 Oct; 24(1):78-85. PMID: 4148299.
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