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CRAIG J HARTLEY

TitleProfessor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address Fondren Brown Bldg- Rm F643
Houston TX 77030
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    Other Positions
    TitleProfessor Emeritus
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Physiology & Biophysics
    DivisionMolecular Physiology & Biophysics


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Medrano G, Hermosillo-Rodriguez J, Pham T, Granillo A, Hartley CJ, Reddy A, Osuna PM, Entman ML, Taffet GE. Left Atrial Volume and Pulmonary Artery Diameter Are Noninvasive Measures of Age-Related Diastolic Dysfunction in Mice. J Gerontol A Biol Sci Med Sci. 2016 Sep; 71(9):1141-50. PMID: 26511013.
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    2. Yang EY, Brunner G, Dokainish H, Hartley CJ, Taffet G, Lakkis N, Taylor AA, Misra A, McCulloch ML, Morrisett JD, Virani SS, Ballantyne CM, Nagueh SF, Nambi V. Application of speckle-tracking in the evaluation of carotid artery function in subjects with hypertension and diabetes. J Am Soc Echocardiogr. 2013 Aug; 26(8):901-909.e1. PMID: 23759168; PMCID: PMC3725197.
    3. Reddy AK, Hartley CJ, Pham TT, Darlington G, Entman ML, Taffet GE. Young little mice express a premature cardiovascular aging phenotype. J Gerontol A Biol Sci Med Sci. 2014 Feb; 69(2):152-9. PMID: 23682160; PMCID: PMC4038241.
    4. Hartley CJ, Naghavi M, Parodi O, Pattichis CS, Poon CC, Zhang YT. Cardiovascular health informatics: risk screening and intervention. IEEE Trans Inf Technol Biomed. 2012 Sep; 16(5):791-4. PMID: 22997187; PMCID: PMC3896083.
    5. Quaini A, Canic S, Glowinski R, Igo S, Hartley CJ, Zoghbi W, Little S. Validation of a 3D computational fluid-structure interaction model simulating flow through an elastic aperture. J Biomech. 2012 Jan 10; 45(2):310-8. PMID: 22138194; PMCID: PMC3274367.
    6. Yang EY, Dokainish H, Virani SS, Misra A, Pritchett AM, Lakkis N, Brunner G, Bobek J, McCulloch ML, Hartley CJ, Ballantyne CM, Nagueh SF, Nambi V. Segmental analysis of carotid arterial strain using speckle-tracking. J Am Soc Echocardiogr. 2011 Nov; 24(11):1276-1284.e5. PMID: 21907541; PMCID: PMC3200442.
    7. Lloyd EE, Crossland RF, Phillips SC, Marrelli SP, Reddy AK, Taffet GE, Hartley CJ, Bryan RM. Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice. Hypertension. 2011 Oct; 58(4):672-8. PMID: 21876070; PMCID: PMC3205080.
    8. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Doppler velocity measurements from large and small arteries of mice. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H269-78. PMID: 21572013; PMCID: PMC3154663.
    9. Hanasono MM, Kocak E, Ogunleye O, Hartley CJ, Miller MJ. One versus two venous anastomoses in microvascular free flap surgery. Plast Reconstr Surg. 2010 Nov; 126(5):1548-57. PMID: 21042112; PMCID: PMC3348705.
    10. Hartley CJ, Reddy AK, Madala S, Entman ML, Taffet GE. Feasibility of dual Doppler velocity measurements to estimate volume pulsations of an arterial segment. Ultrasound Med Biol. 2010 Jul; 36(7):1169-75. PMID: 20620703; PMCID: PMC2904320.
    11. Namiranian K, Lloyd EE, Crossland RF, Marrelli SP, Taffet GE, Reddy AK, Hartley CJ, Bryan RM. Cerebrovascular responses in mice deficient in the potassium channel, TREK-1. Am J Physiol Regul Integr Comp Physiol. 2010 Aug; 299(2):R461-9. PMID: 20357027; PMCID: PMC2928619.
    12. Hartley CJ, Reddy AK, Michael LH, Entman ML, Chintalagattu V, Khakoo AY, Taffet GE. Coronary flow reserve in mice: effects of age, coronary disease, and vascular loading. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:3780-3. PMID: 21096875; PMCID: PMC3341612.
    13. Reddy AK, Madala S, Jones AD, Caro WA, Eberth JF, Pham TT, Taffet GE, Hartley CJ. Multichannel pulsed Doppler signal processing for vascular measurements in mice. Ultrasound Med Biol. 2009 Dec; 35(12):2042-54. PMID: 19854566; PMCID: PMC2900799.
    14. Hanasono MM, Ogunleye O, Yang JS, Hartley CJ, Miller MJ. Changes in blood velocity following microvascular free tissue transfer. J Reconstr Microsurg. 2009 Sep; 25(7):417-24. PMID: 19593731; PMCID: PMC2905151.
    15. Gul KM, Ahmadi N, Wang Z, Jamieson C, Nasir K, Metcalfe R, Hecht HS, Hartley CJ, Naghavi M. Digital thermal monitoring of vascular function: a novel tool to improve cardiovascular risk assessment. Vasc Med. 2009 May; 14(2):143-8. PMID: 19366821; PMCID: PMC3349085.
    16. Pirat B, Little SH, Igo SR, McCulloch M, Nosé Y, Hartley CJ, Zoghbi WA. Direct measurement of proximal isovelocity surface area by real-time three-dimensional color Doppler for quantitation of aortic regurgitant volume: an in vitro validation. J Am Soc Echocardiogr. 2009 Mar; 22(3):306-13. PMID: 19168322; PMCID: PMC3348870.
    17. Hartley CJ, Reddy AK, Michael LH, Entman ML, Taffet GE. Coronary flow reserve as an index of cardiac function in mice with cardiovascular abnormalities. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1094-7. PMID: 19963485; PMCID: PMC3341618.
    18. Reddy AK, Namiranian K, Lloyd EE, Bryan RM, Taffet GE, Hartley CJ. Effect of isoflurane on aortic impedance in mice. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1104-5. PMID: 19964748; PMCID: PMC3341611.
    19. McQuilkin GL, Panthagani D, Metcalfe RW, Hassan H, Yen AA, Naghavi M, Hartley CJ. Digital thermal monitoring (DTM) of vascular reactivity closely correlates with Doppler flow velocity. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1100-3. PMID: 19964497; PMCID: PMC3341617.
    20. Little SH, Pirat B, Kumar R, Igo SR, McCulloch M, Hartley CJ, Xu J, Zoghbi WA. Three-dimensional color Doppler echocardiography for direct measurement of vena contracta area in mitral regurgitation: in vitro validation and clinical experience. JACC Cardiovasc Imaging. 2008 Nov; 1(6):695-704. PMID: 19356505; PMCID: PMC3357190.
    21. Doursout MF, Oguchi T, Fischer UM, Liang Y, Chelly B, Hartley CJ, Chelly JE. Distribution of NOS isoforms in a porcine endotoxin shock model. Shock. 2008 Jun; 29(6):692-702. PMID: 17909454; PMCID: PMC3341620.
    22. Pirat B, Khoury DS, Hartley CJ, Tiller L, Rao L, Schulz DG, Nagueh SF, Zoghbi WA. A novel feature-tracking echocardiographic method for the quantitation of regional myocardial function: validation in an animal model of ischemia-reperfusion. J Am Coll Cardiol. 2008 Feb 12; 51(6):651-9. PMID: 18261685; PMCID: PMC3348770.
    23. Little SH, Igo SR, McCulloch M, Hartley CJ, Nosé Y, Zoghbi WA. Three-dimensional ultrasound imaging model of mitral valve regurgitation: design and evaluation. Ultrasound Med Biol. 2008 Apr; 34(4):647-54. PMID: 18255217; PMCID: PMC3348787.
    24. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, Taffet GE. Doppler estimation of reduced coronary flow reserve in mice with pressure overload cardiac hypertrophy. Ultrasound Med Biol. 2008 Jun; 34(6):892-901. PMID: 18255218; PMCID: PMC2453594.
    25. Hartley CJ, Reddy AK, Taffet GE. In-vitro evaluation of sensors and amplifiers to measure left ventricular pressure in mice. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:965-8. PMID: 19162818; PMCID: PMC3341624.
    26. Reddy AK, Taffet GE, Hartley CJ. Aortic impedance in Little mice. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:1397-8. PMID: 19162929; PMCID: PMC3345796.
    27. Reddy AK, Amador-Noguez D, Darlington GJ, Scholz BA, Michael LH, Hartley CJ, Entman ML, Taffet GE. Cardiac function in young and old Little mice. J Gerontol A Biol Sci Med Sci. 2007 Dec; 62(12):1319-25. PMID: 18166681; PMCID: PMC2771398.
    28. Little SH, Igo SR, Pirat B, McCulloch M, Hartley CJ, Nosé Y, Zoghbi WA. In vitro validation of real-time three-dimensional color Doppler echocardiography for direct measurement of proximal isovelocity surface area in mitral regurgitation. Am J Cardiol. 2007 May 15; 99(10):1440-7. PMID: 17493476; PMCID: PMC3348701.
    29. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, Taffet GE. Effects of isoflurane on coronary blood flow velocity in young, old and ApoE(-/-) mice measured by Doppler ultrasound. Ultrasound Med Biol. 2007 Apr; 33(4):512-21. PMID: 17346873; PMCID: PMC2048667.
    30. Cani? S, Hartley CJ, Rosenstrauch D, Tambaca J, Guidoboni G, Mikeli? A. Blood flow in compliant arteries: an effective viscoelastic reduced model, numerics, and experimental validation. Ann Biomed Eng. 2006 Apr; 34(4):575-92. PMID: 16550449.
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    31. Quick CM, Berger DS, Stewart RH, Laine GA, Hartley CJ, Noordergraaf A. Resolving the hemodynamic inverse problem. IEEE Trans Biomed Eng. 2006 Mar; 53(3):361-8. PMID: 16532762.
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    32. Reddy AK, Taffet GE, Li YH, Lim SW, Pham TT, Pocius JS, Entman ML, Michael LH, Hartley CJ. Pulsed Doppler signal processing for use in mice: applications. IEEE Trans Biomed Eng. 2005 Oct; 52(10):1771-83. PMID: 16235663.
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    33. Reddy AK, Jones AD, Martono C, Caro WA, Madala S, Hartley CJ. Pulsed Doppler signal processing for use in mice: design and evaluation. IEEE Trans Biomed Eng. 2005 Oct; 52(10):1764-70. PMID: 16235662.
      View in: PubMed
    34. Ladd AN, Taffet G, Hartley C, Kearney DL, Cooper TA. Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Mol Cell Biol. 2005 Jul; 25(14):6267-78. PMID: 15988035; PMCID: PMC1168813.
    35. Carlier S, Kakadiaris IA, Dib N, Vavuranakis M, O'Malley SM, Gul K, Hartley CJ, Metcalfe R, Mehran R, Stefanadis C, Falk E, Stone G, Leon M, Naghavi M. Vasa vasorum imaging: a new window to the clinical detection of vulnerable atherosclerotic plaques. Curr Atheroscler Rep. 2005 Mar; 7(2):164-9. PMID: 15727733.
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    36. Reddy A, Pham T, Michael L, Taffet G, Hartley C. Is aortic impedance altered in dwarf mice? Conf Proc IEEE Eng Med Biol Soc. 2005; 1:605-6. PMID: 17282254.
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    37. Hartley C, Reddy A, Entman M, Michael L, Taffet G, Madala S. Characterization of arterial wave propagation and reflection in mice. Conf Proc IEEE Eng Med Biol Soc. 2005; 1:601-4. PMID: 17282253.
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    38. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Noninvasive ultrasonic measurement of arterial wall motion in mice. Am J Physiol Heart Circ Physiol. 2004 Sep; 287(3):H1426-32. PMID: 15317682.
      View in: PubMed
    39. Appleton GO, Li Y, Taffet GE, Hartley CJ, Michael LH, Entman ML, Roberts R, Khoury DS. Determinants of cardiac electrophysiological properties in mice. J Interv Card Electrophysiol. 2004 Aug; 11(1):5-14. PMID: 15273447.
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    40. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Noninvasive ultrasonic measurement of arterial wall motion in mice. Conf Proc IEEE Eng Med Biol Soc. 2004; 5:3688-91. PMID: 17271094.
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    41. Reddy AK, Taffet GE, Prchal JF, Michael LH, Entman ML, Hartley CJ. Effect of cellular elements on pressure-velocity relationship in mice. Conf Proc IEEE Eng Med Biol Soc. 2004; 5:3720-2. PMID: 17271102.
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    42. Cani? S, Tambaca J, Mikeli? A, Hartley CJ, Mirkovi? D, Chavez J, Rosenstrauch D. Blood flow through axially symmetric sections of compliant vessels: new effective closed models. Conf Proc IEEE Eng Med Biol Soc. 2004; 5:3696-9. PMID: 17271096.
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    43. Li YH, Reddy AK, Ochoa LN, Pham TT, Hartley CJ, Michael LH, Entman ML, Taffet GE. Effect of age on peripheral vascular response to transverse aortic banding in mice. J Gerontol A Biol Sci Med Sci. 2003 Oct; 58(10):B895-9. PMID: 14570855.
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    44. Li YH, Reddy AK, Taffet GE, Michael LH, Entman ML, Hartley CJ. Doppler evaluation of peripheral vascular adaptations to transverse aortic banding in mice. Ultrasound Med Biol. 2003 Sep; 29(9):1281-9. PMID: 14553805.
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    45. Reddy AK, Li YH, Pham TT, Ochoa LN, Trevino MT, Hartley CJ, Michael LH, Entman ML, Taffet GE. Measurement of aortic input impedance in mice: effects of age on aortic stiffness. Am J Physiol Heart Circ Physiol. 2003 Oct; 285(4):H1464-70. PMID: 12775560.
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    46. Reddy AK, Taffet GE, Madala S, Michael LH, Entman ML, Hartley CJ. Noninvasive blood pressure measurement in mice using pulsed Doppler ultrasound. Ultrasound Med Biol. 2003 Mar; 29(3):379-85. PMID: 12706189.
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    47. Doursout MF, Joseph PM, Liang YY, Hartley CJ, Chelly JE. Role of propofol and its solvent, intralipid, in nitric oxide-induced peripheral vasodilatation in dogs. Br J Anaesth. 2002 Sep; 89(3):492-8. PMID: 12402731.
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    48. Gould KE, Taffet GE, Michael LH, Christie RM, Konkol DL, Pocius JS, Zachariah JP, Chaupin DF, Daniel SL, Sandusky GE, Hartley CJ, Entman ML. Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure. Am J Physiol Heart Circ Physiol. 2002 Feb; 282(2):H615-21. PMID: 11788410.
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    49. Hartley CJ, Taffet GE, Reddy AK, Entman ML, Michael LH. Noninvasive cardiovascular phenotyping in mice. ILAR J. 2002; 43(3):147-58. PMID: 12105382.
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    50. Overcast JD, Ensley AE, Buccafusco CJ, Cundy C, Broadnax RA, He S, Yoganathan AP, Pollock SH, Hartley CJ, May SW. Evaluation of cardiovascular parameters of a selenium-based antihypertensive using pulsed Doppler ultrasound. J Cardiovasc Pharmacol. 2001 Sep; 38(3):337-46. PMID: 11486238.
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    51. Jackson KA, Majka SM, Wang H, Pocius J, Hartley CJ, Majesky MW, Entman ML, Michael LH, Hirschi KK, Goodell MA. Regeneration of ischemic cardiac muscle and vascular endothelium by adult stem cells. J Clin Invest. 2001 Jun; 107(11):1395-402. PMID: 11390421; PMCID: PMC209322.
    52. Goodell MA, Jackson KA, Majka SM, Mi T, Wang H, Pocius J, Hartley CJ, Majesky MW, Entman ML, Michael LH, Hirschi KK. Stem cell plasticity in muscle and bone marrow. Ann N Y Acad Sci. 2001 Jun; 938:208-18; discussion 218-20. PMID: 11458510.
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    53. Oguchi T, Doursout MF, Kashimoto S, Liang YY, Hartley CJ, Chelly JE. Role of heparin and nitric oxide in the cardiac and regional hemodynamic properties of protamine in conscious chronically instrumented dogs. Anesthesiology. 2001 Jun; 94(6):1016-25. PMID: 11465593.
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    54. Doursout MF, Hartley CJ, Chelly JE. Comparison of cardiac and regional hemodynamic responses to N-methyl-L-arginine and aminoguanidine infusions in conscious pigs. J Cardiovasc Pharmacol. 2001 Apr; 37(4):349-58. PMID: 11300647.
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    55. Doursout MF, Wouters P, Kashimoto S, Hartley CJ, Rabinovitz R, Chelly JE. Measurement of cardiac function in conscious rats. Ultrasound Med Biol. 2001 Feb; 27(2):195-202. PMID: 11316528.
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    56. Hartley CJ, Reddy AK, Madala S, Martin-McNulty B, Vergona R, Sullivan ME, Halks-Miller M, Taffet GE, Michael LH, Entman ML, Wang YX. Hemodynamic changes in apolipoprotein E-knockout mice. Am J Physiol Heart Circ Physiol. 2000 Nov; 279(5):H2326-34. PMID: 11045969.
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    57. He ZX, Cwajg E, Hwang W, Hartley CJ, Funk E, Michael LH, Verani MS. Myocardial blood flow and myocardial uptake of (201)Tl and (99m)Tc-sestamibi during coronary vasodilation induced by CGS-21680, a selective adenosine A(2A) receptor agonist. Circulation. 2000 Jul 25; 102(4):438-44. PMID: 10908217.
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    58. Doursout MF, Kilbourn RG, Hartley CJ, Chelly JE. Effects of N-methyl-L-arginine on cardiac and regional blood flow in a dog endotoxin shock model. J Crit Care. 2000 Mar; 15(1):22-9. PMID: 10757195.
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    59. Ulich TR, del Castillo J, Senaldi G, Hartley C, Molineux G. PEG-rHuMGDF promotes multilineage hematopoietic recovery in myelosuppressed mice. Exp Hematol. 1999 Dec; 27(12):1776-81. PMID: 10641595.
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    60. Milner DJ, Taffet GE, Wang X, Pham T, Tamura T, Hartley C, Gerdes AM, Capetanaki Y. The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function. J Mol Cell Cardiol. 1999 Nov; 31(11):2063-76. PMID: 10591032.
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    61. Michael LH, Ballantyne CM, Zachariah JP, Gould KE, Pocius JS, Taffet GE, Hartley CJ, Pham TT, Daniel SL, Funk E, Entman ML. Myocardial infarction and remodeling in mice: effect of reperfusion. Am J Physiol. 1999 Aug; 277(2 Pt 2):H660-8. PMID: 10444492.
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    62. Hartley CJ, Lacy JL, Dai D, Nayak N, Taffet GE, Entman ML, Michael LH. Functional cardiac imaging in mice using Ta-178. Nat Med. 1999 Feb; 5(2):237-9. PMID: 9930875.
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    63. Horikawa S, Ishida T, Igawa K, Kawanishi K, Hartley CJ, Takahara J. Both positive and negative portal venous and hepatic arterial glucose gradients stimulate hepatic glucose uptake after the same amount of glucose is infused into the splanchnic bed in conscious dogs. Metabolism. 1998 Nov; 47(11):1295-302. PMID: 9826203.
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    64. Taffet GE, Pham TT, Hartley CJ. The age-associated alterations in late diastolic function in mice are improved by caloric restriction. J Gerontol A Biol Sci Med Sci. 1997 Nov; 52(6):B285-90. PMID: 9402929.
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    65. Hartley CJ, Taffet GE, Michael LH, Pham TT, Entman ML. Noninvasive determination of pulse-wave velocity in mice. Am J Physiol. 1997 Jul; 273(1 Pt 2):H494-500. PMID: 9249523.
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    66. Juan TS, McNiece IK, Van G, Lacey D, Hartley C, McElroy P, Sun Y, Argento J, Hill D, Yan XQ, Fletcher FA. Chronic expression of murine flt3 ligand in mice results in increased circulating white blood cell levels and abnormal cellular infiltrates associated with splenic fibrosis. Blood. 1997 Jul 1; 90(1):76-84. PMID: 9207441.
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    67. Nakanishi I, Ishida T, Hosokawa H, Kawanishi K, Hartley CJ, Takahara J. The effect of somatostatin analogue on glucose homeostasis in conscious dogs. Acta Med Okayama. 1997 Feb; 51(1):1-7. PMID: 9057928.
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    68. Soltero ER, Glaeser DH, Michael LH, Hartley CJ, Earle NR, Li Z, Lawrie GM. Hemodynamic effects of different pacing ratios in chronic dynamic double cardiomyoplasty. Ann Thorac Surg. 1996 Nov; 62(5):1380-7. PMID: 8893572.
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    69. Chelly JE, Doursout MF, Lechevalier T, Liang YY, Chelly F, Hartley C, Kilbourn RG. Cardiac and regional hemodynamic interactions between halothane and nitric oxide synthase activity in dogs. Anesthesiology. 1996 Jul; 85(1):142-9. PMID: 8694360.
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    70. Molineux G, Hartley C, McElroy P, McCrea C, McNiece IK. Megakaryocyte growth and development factor accelerates platelet recovery in peripheral blood progenitor cell transplant recipients. Blood. 1996 Jul 1; 88(1):366-76. PMID: 8704197.
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    71. Taffet GE, Hartley CJ, Wen X, Pham T, Michael LH, Entman ML. Noninvasive indexes of cardiac systolic and diastolic function in hyperthyroid and senescent mouse. Am J Physiol. 1996 Jun; 270(6 Pt 2):H2204-9. PMID: 8764275.
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    72. Michael LH, Entman ML, Hartley CJ, Youker KA, Zhu J, Hall SR, Hawkins HK, Berens K, Ballantyne CM. Myocardial ischemia and reperfusion: a murine model. Am J Physiol. 1995 Dec; 269(6 Pt 2):H2147-54. PMID: 8594926.
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    73. Yan XQ, Lacey D, Fletcher F, Hartley C, McElroy P, Sun Y, Xia M, Mu S, Saris C, Hill D, Hawley RG, McNiece IK. Chronic exposure to retroviral vector encoded MGDF (mpl-ligand) induces lineage-specific growth and differentiation of megakaryocytes in mice. Blood. 1995 Dec 1; 86(11):4025-33. PMID: 7492757.
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    74. Yan XQ, Hartley C, McElroy P, Chang A, McCrea C, McNiece I. Peripheral blood progenitor cells mobilized by recombinant human granulocyte colony-stimulating factor plus recombinant rat stem cell factor contain long-term engrafting cells capable of cellular proliferation for more than two years as shown by serial transplantation in mice. Blood. 1995 May 1; 85(9):2303-7. PMID: 7537109.
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    75. Tang XL, McCay PB, Sun JZ, Hartley CJ, Schleman M, Bolli R. Inhibitory effect of a hydrophilic alpha-tocopherol analogue, MDL 74,405, on generation of free radicals in stunned myocardium in dogs. Free Radic Res. 1995 Apr; 22(4):293-302. PMID: 7633559.
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    76. Hartley CJ, Michael LH, Entman ML. Noninvasive measurement of ascending aortic blood velocity in mice. Am J Physiol. 1995 Jan; 268(1 Pt 2):H499-505. PMID: 7840299.
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    77. Yan XQ, Briddell R, Hartley C, Stoney G, Samal B, McNiece I. Mobilization of long-term hematopoietic reconstituting cells in mice by the combination of stem cell factor plus granulocyte colony-stimulating factor. Blood. 1994 Aug 1; 84(3):795-9. PMID: 7519076.
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    78. Soltero ER, Glaeser DH, Michael LH, Hartley CJ, Earle NR, Lawrie GM. Acute impairment of coronary blood flow by dynamic cardiomyoplasty. Ann Thorac Surg. 1994 Jul; 58(1):121-7. PMID: 8037509.
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    79. Jeroudi MO, Hartley CJ, Bolli R. Myocardial reperfusion injury: role of oxygen radicals and potential therapy with antioxidants. Am J Cardiol. 1994 Mar 10; 73(6):2B-7B. PMID: 8141076.
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    80. Hartley CJ, Ying H, Motamedi M. Ultrasonic Doppler detection of laser-tissue interaction. Ultrasound Med Biol. 1994; 20(7):655-63. PMID: 7810026.
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    81. Soltero ER, Michael LH, Glaeser DH, Hartley CJ, Earle NR, Lawrie GM. New configuration of double cardiomyoplasty based on studies of the length-tension properties of the latissimus dorsi muscle. J Thorac Cardiovasc Surg. 1993 Nov; 106(5):842-9. PMID: 8231206.
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    82. Kashimoto S, Doursout MF, Hartley C, Chelly JE. Effects of thiopental and ketamine on cardiac function during moderate hemorrhage in chronically instrumented rats. J Cardiovasc Pharmacol. 1993 May; 21(5):829-33. PMID: 7685456.
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    83. Hartley CJ, Cheirif J, Collier KR, Bravenec JS, Mickelson JK. Doppler quantification of echo-contrast injections in vivo. Ultrasound Med Biol. 1993; 19(4):269-78. PMID: 8346601.
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    84. Bernard JM, Doursout MF, Wouters P, Hartley CJ, Merin RG, Chelly JE. Effects of sevoflurane and isoflurane on hepatic circulation in the chronically instrumented dog. Anesthesiology. 1992 Sep; 77(3):541-5. PMID: 1519792.
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    85. Bolli R, Hartley CJ, Rabinovitz RS. Clinical relevance of myocardial "stunning". Cardiovasc Drugs Ther. 1991 Oct; 5(5):877-90. PMID: 1756133.
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    86. Hartley CJ, Litowitz H, Rabinovitz RS, Zhu WX, Chelly JE, Michael LH, Bolli R. An ultrasonic method for measuring tissue displacement: technical details and validation for measuring myocardial thickening. IEEE Trans Biomed Eng. 1991 Aug; 38(8):735-47. PMID: 1937506.
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    87. Bernard JM, Doursout MF, Wouters P, Hartley CJ, Cohen M, Merin RG, Chelly JE. Effects of enflurane and isoflurane on hepatic and renal circulations in chronically instrumented dogs. Anesthesiology. 1991 Feb; 74(2):298-302. PMID: 1990904.
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    88. Doursout MF, Hartley CJ, Johnson D, Chelly JE. Effects of prostaglandins and the autonomic nervous system on the vasodilatory properties of nitroglycerin in conscious dogs. J Cardiovasc Pharmacol. 1990 Sep; 16(3):417-22. PMID: 1700212.
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    89. Gardiner SM, Compton AM, Bennett T, Hartley CJ. Can pulsed Doppler technique measure changes in aortic blood flow in conscious rats? Am J Physiol. 1990 Aug; 259(2 Pt 2):H448-56. PMID: 2201207.
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    90. Rabinovitz RS, Hartley CJ, Michael LH, Entman ML, Hawkins HK, Sekela ME, Noon GP. Implantable sensor for intraoperative and postoperative monitoring of blood flow: a preliminary report. J Vasc Surg. 1990 Aug; 12(2):148-57. PMID: 2199684.
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    91. Michael LH, Zhang Z, Hartley CJ, Bolli R, Taylor AA, Entman ML. Thromboxane B2 in cardiac lymph. Effect of superoxide dismutase and catalase during myocardial ischemia and reperfusion. Circ Res. 1990 Apr; 66(4):1040-4. PMID: 2317886.
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    92. Gest AL, Hansen TN, Moise AA, Hartley CJ. Atrial tachycardia causes hydrops in fetal lambs. Am J Physiol. 1990 Apr; 258(4 Pt 2):H1159-63. PMID: 2331003.
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    93. Bolli R, Hartley CJ, Chelly JE, Patel BS, Rabinovitz RS, Jeroudi MO, Roberts R, Noon G. An accurate, nontraumatic ultrasonic method to monitor myocardial wall thickening in patients undergoing cardiac surgery. J Am Coll Cardiol. 1990 Apr; 15(5):1055-65. PMID: 2179360.
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    94. Parker GW, Michael LH, Hartley CJ, Skinner JE, Entman ML. Central beta-adrenergic mechanisms may modulate ischemic ventricular fibrillation in pigs. Circ Res. 1990 Feb; 66(2):259-70. PMID: 2153467.
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    95. Hill DC, Wouters PF, Chelly JE, Doursout MF, Abernethy DR, Hartley CJ, Merin RG. Cardiovascular effects of and interaction between calcium blocking drugs and anesthetics in chronically instrumented dogs: VII. Verapamil and thiopental. Anesthesiology. 1989 Oct; 71(4):586-90. PMID: 2802216.
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    96. Bolli R, Patel BS, Hartley CJ, Thornby JI, Jeroudi MO, Roberts R. Nonuniform transmural recovery of contractile function in stunned myocardium. Am J Physiol. 1989 Aug; 257(2 Pt 2):H375-85. PMID: 2764126.
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    97. Charlat ML, O'Neill PG, Hartley CJ, Roberts R, Bolli R. Prolonged abnormalities of left ventricular diastolic wall thinning in the "stunned" myocardium in conscious dogs: time course and relation to systolic function. J Am Coll Cardiol. 1989 Jan; 13(1):185-94. PMID: 2909566.
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    98. Hartley CJ. Review of intracoronary Doppler catheters. Int J Card Imaging. 1989; 4(2-4):159-68. PMID: 2671167.
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    99. Adrogué HJ, Chap Z, Okuda Y, Michael L, Hartley C, Entman M, Field JB. Acidosis-induced glucose intolerance is not prevented by adrenergic blockade. Am J Physiol. 1988 Dec; 255(6 Pt 1):E812-23. PMID: 3144181.
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    100. Doursout MF, Chelly JE, Hartley CJ, Szilagyi J, Montastruc JL, Buckley JP. Regional blood flows and cardiac function changes induced by angiotensin II in conscious dogs. J Pharmacol Exp Ther. 1988 Aug; 246(2):591-6. PMID: 2969978.
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    101. Zoghbi WA, Charlat ML, Bolli R, Zhu WX, Hartley CJ, Quinones MA. Quantitative assessment of left ventricular wall motion by two-dimensional echocardiography: validation during reversible ischemia in the conscious dog. J Am Coll Cardiol. 1988 Apr; 11(4):851-60. PMID: 3351154.
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    102. Bolli R, Patel BS, Zhu WX, O'Neill PG, Hartley CJ, Charlat ML, Roberts R. The iron chelator desferrioxamine attenuates postischemic ventricular dysfunction. Am J Physiol. 1987 Dec; 253(6 Pt 2):H1372-80. PMID: 3425739.
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    103. Zoghbi WA, Charlat ML, Bolli R, Kopelen H, Hartley CJ, Roberts R, Quinones MA. End-systolic radius to thickness ratio: an echocardiographic index of regional performance during reversible myocardial ischemia in the conscious dog. J Am Coll Cardiol. 1987 Nov; 10(5):1113-21. PMID: 3668107.
      View in: PubMed
    104. Jain A, Demer LL, Raizner AE, Hartley CJ, Lewis JM, Roberts R. In vivo assessment of vascular dilatation during percutaneous transluminal coronary angioplasty. Am J Cardiol. 1987 Nov 1; 60(13):988-92. PMID: 2960231.
      View in: PubMed
    105. O'Neill PG, Charlat ML, Kim HS, Pocius J, Michael LH, Hartley CJ, Zhu WX, Roberts R, Bolli R. Lipoxygenase inhibitor nafazatrom fails to attenuate postischaemic ventricular dysfunction. Cardiovasc Res. 1987 Oct; 21(10):755-60. PMID: 3125975.
      View in: PubMed
    106. Bolli R, Zhu WX, Hartley CJ, Michael LH, Repine JE, Hess ML, Kukreja RC, Roberts R. Attenuation of dysfunction in the postischemic 'stunned' myocardium by dimethylthiourea. Circulation. 1987 Aug; 76(2):458-68. PMID: 3111744.
      View in: PubMed
    107. Chelly JE, Hysing ES, Abernethy DR, Doursout MF, Hartley CJ, Guerret M, Merin RG. Role of isoflurane on hemodynamic properties and disposition of nicardipine. J Pharmacol Exp Ther. 1987 Jun; 241(3):899-906. PMID: 3598907.
      View in: PubMed
    108. Chap Z, Ishida T, Chou J, Hartley CJ, Entman ML, Brandenburg D, Jones RH, Field JB. First-pass hepatic extraction and metabolic effects of insulin and insulin analogues. Am J Physiol. 1987 Feb; 252(2 Pt 1):E209-17. PMID: 3548421.
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    109. Merin RG, Chelly JE, Hysing ES, Rogers K, Dlewati A, Hartley CJ, Abernethy DR, Doursout MF. Cardiovascular effects of and interaction between calcium blocking drugs and anesthetics in chronically instrumented dogs. IV. Chronically administered oral verapamil and halothane, enflurane, and isoflurane. Anesthesiology. 1987 Feb; 66(2):140-6. PMID: 3813076.
      View in: PubMed
    110. Sibley DH, Millar HD, Hartley CJ, Whitlow PL. Subselective measurement of coronary blood flow velocity using a steerable Doppler catheter. J Am Coll Cardiol. 1986 Dec; 8(6):1332-40. PMID: 3537059.
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    111. Myers ML, Bolli R, Lekich RF, Hartley CJ, Roberts R. N-2-mercaptopropionylglycine improves recovery of myocardial function after reversible regional ischemia. J Am Coll Cardiol. 1986 Nov; 8(5):1161-8. PMID: 3760390.
      View in: PubMed
    112. Chap Z, Jones RH, Chou J, Hartley CJ, Entman ML, Field JB. Effect of dexamethasone on hepatic glucose and insulin metabolism after oral glucose in conscious dogs. J Clin Invest. 1986 Nov; 78(5):1355-61. PMID: 3534000; PMCID: PMC423834.
    113. Zhu WX, Myers ML, Hartley CJ, Roberts R, Bolli R. Validation of a single crystal for measurement of transmural and epicardial thickening. Am J Physiol. 1986 Nov; 251(5 Pt 2):H1045-55. PMID: 3535539.
      View in: PubMed
    114. Hysing ES, Chelly JE, Doursout MF, Hartley C, Merin RG. Cardiovascular effects of and interaction between calcium blocking drugs and anesthetics in chronically instrumented dogs. III. Nicardipine and isoflurane. Anesthesiology. 1986 Oct; 65(4):385-91. PMID: 3767036.
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    115. Chelly JE, Doursout MF, Begaud B, Tsao CC, Hartley CJ. Effects of hydralazine on regional blood flow in conscious dogs. J Pharmacol Exp Ther. 1986 Aug; 238(2):665-9. PMID: 3735136.
      View in: PubMed
    116. Rogers K, Hysing ES, Merin RG, Taylor A, Hartley C, Chelly JE. Cardiovascular effects of and interaction between calcium blocking drugs and anesthetics in chronically instrumented dogs. II. Verapamil, enflurane, and isoflurane. Anesthesiology. 1986 May; 64(5):568-75. PMID: 3963477.
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    117. Chelly JE, Rogers K, Hysing ES, Taylor A, Hartley C, Merin RG. Cardiovascular effects of and interaction between calcium blocking drugs and anesthetics in chronically instrumented dogs. I. Verapamil and halothane. Anesthesiology. 1986 May; 64(5):560-7. PMID: 3963476.
      View in: PubMed
    118. Chap Z, Ishida T, Chou J, Michael L, Hartley C, Entman M, Field JB. Effects of alpha and beta adrenergic blockade on hepatic glucose balance before and after oral glucose. Role of insulin and glucagon. J Clin Invest. 1986 Apr; 77(4):1357-69. PMID: 2870078; PMCID: PMC424496.
    119. Chap Z, Ishida T, Chou J, Hartley CJ, Lewis RM, Entman M, Field JB. Effect of metabolic clearance rate and hepatic extraction of insulin on hepatic and peripheral contributions to hypoglycemia. J Clin Invest. 1985 Dec; 76(6):2222-34. PMID: 3908485; PMCID: PMC424345.
    120. Bolli R, Zhu WX, Myers ML, Hartley CJ, Roberts R. Beta-adrenergic stimulation reverses postischemic myocardial dysfunction without producing subsequent functional deterioration. Am J Cardiol. 1985 Dec 1; 56(15):964-8. PMID: 2866704.
      View in: PubMed
    121. Myers ML, Bolli R, Lekich RF, Hartley CJ, Roberts R. Enhancement of recovery of myocardial function by oxygen free-radical scavengers after reversible regional ischemia. Circulation. 1985 Oct; 72(4):915-21. PMID: 4028384.
      View in: PubMed
    122. Chap Z, Ishida T, Chou J, Lewis R, Hartley C, Entman M, Field JB. Effects of atropine and gastric inhibitory polypeptide on hepatic glucose uptake and insulin extraction in conscious dogs. J Clin Invest. 1985 Sep; 76(3):1174-81. PMID: 3900134; PMCID: PMC424018.
    123. Wilson RF, Laughlin DE, Ackell PH, Chilian WM, Holida MD, Hartley CJ, Armstrong ML, Marcus ML, White CW. Transluminal, subselective measurement of coronary artery blood flow velocity and vasodilator reserve in man. Circulation. 1985 Jul; 72(1):82-92. PMID: 3159506.
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    124. Guyton JR, Hartley CJ. Flow restriction of one carotid artery in juvenile rats inhibits growth of arterial diameter. Am J Physiol. 1985 Apr; 248(4 Pt 2):H540-6. PMID: 3885757.
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    125. Chelly J, Doursout MF, Hysing E, Hartley C. Role of prostaglandin in nitroglycerin induced vasodilation in conscious dogs. Proc West Pharmacol Soc. 1985; 28:1-3. PMID: 3934674.
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    126. Chelly JE, Doursout MF, Hartley CJ, Huang YK, Buckley JP. Hemodynamic effects of the intraventricular administration of angiotensin II and renin in awake dogs. Clin Exp Hypertens A. 1985; 7(8):1083-95. PMID: 3899420.
      View in: PubMed
    127. Ishida T, Chap Z, Chou J, Lewis RM, Hartley CJ, Entman ML, Field JB. Effects of portal and peripheral venous insulin infusion on glucose production and utilization in depancreatized, conscious dogs. Diabetes. 1984 Oct; 33(10):984-90. PMID: 6383906.
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    128. Dole WP, Richards KL, Hartley CJ, Alexander GM, Campbell AB, Bishop VS. Diastolic coronary artery pressure-flow velocity relationships in conscious man. Cardiovasc Res. 1984 Sep; 18(9):548-54. PMID: 6467272.
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    129. Seidel CL, Lewis RM, Bowers R, Bukoski RD, Kim HS, Allen JC, Hartley C. Adaptation of canine saphenous veins to grafting. Correlation of contractility and contractile protein content. Circ Res. 1984 Jul; 55(1):102-9. PMID: 6744525.
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    130. Ishida T, Chap Z, Chou J, Lewis RM, Hartley CJ, Entman ML, Field JB. Hepatic extraction of exogenous insulin in depancreatized conscious dogs. Am J Physiol. 1984 Apr; 246(4 Pt 1):E369-79. PMID: 6372507.
      View in: PubMed
    131. Chelly J, Doursout MF, Hartley C, Buckley JP. Hemodynamic effects of angiotensin II and bradykinin infused intraventricularly in conscious dogs. Clin Exp Hypertens A. 1984; 6(10-11):2037-40. PMID: 6532589.
      View in: PubMed
    132. Voyles WF, Greene ER, Altobelli SA, Hartley CJ. In vitro and in vivo studies using a 4F pulsed Doppler velocimeter catheter system. Biomed Sci Instrum. 1984; 20:17-23. PMID: 6231962.
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    133. Chelly J, Doursout MF, Hartley C, Buckley JP. Hemodynamic effects of chronic intraventricular administration of renin in awake dogs. Clin Exp Hypertens A. 1984; 6(10-11):1921-5. PMID: 6398144.
      View in: PubMed
    134. Hartley CJ, Latson LA, Michael LH, Seidel CL, Lewis RM, Entman ML. Doppler measurement of myocardial thickening with a single epicardial transducer. Am J Physiol. 1983 Dec; 245(6):H1066-72. PMID: 6660307.
      View in: PubMed
    135. Ishida T, Chou MC, Chou J, Lewis RM, Hartley CJ, Entman M, Kimmel JR, Field JB. Absence of hepatic extraction of pancreatic polypeptide in conscious dogs. Am J Physiol. 1983 Oct; 245(4):E401-9. PMID: 6624908.
      View in: PubMed
    136. Ishida T, Chap Z, Chou J, Lewis R, Hartley C, Entman M, Field JB. Differential effects of oral, peripheral intravenous, and intraportal glucose on hepatic glucose uptake and insulin and glucagon extraction in conscious dogs. J Clin Invest. 1983 Aug; 72(2):590-601. PMID: 6348094; PMCID: PMC1129217.
    137. Ishida T, Chou J, Lewis RM, Hartley CJ, Entman M, Field JB. The effect of ingestion of meat on hepatic extraction of insulin and glucagon and hepatic glucose output in conscious dogs. Metabolism. 1983 Jun; 32(6):558-67. PMID: 6341771.
      View in: PubMed
    138. Ishida T, Lewis RM, Hartley CJ, Entman ML, Field JB. Comparison of hepatic extraction of insulin and glucagon in conscious and anesthetized dogs. Endocrinology. 1983 Mar; 112(3):1098-109. PMID: 6337043.
      View in: PubMed
    139. Ezrailson EG, Hanley HG, Hartley CJ, Lewis RM, Entman ML, Schwartz A. Studies on the mechanism of an antibiotic ionophore, R02-2985 (X537A) in the conscious chronically instrumented dog: involvement of the prostaglandin synthetic pathway. Cardiovasc Res. 1982 Nov; 16(11):670-4. PMID: 7168844.
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    140. Driscoll DJ, Fukushige J, Hartley C, Lewis RM, Entman ML. Hemodynamic effects of pancuronium bromide in chronically instrumented dogs. Crit Care Med. 1982 Jan; 10(1):41-2. PMID: 7056053.
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    141. Driscoll DJ, Fukushige J, Lewis RM, Hartley CJ, Entman MJ. The comparative hemodynamic effects of propranolol in chronically instrumented puppies and adult dogs. Biol Neonate. 1982; 41(1-2):8-15. PMID: 7066441.
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    142. Miller RR, Palomo AR, Brandon TA, Hartley CJ, Quinones MA. Combined vasodilator and inotropic therapy of heart failure: experimental and clinical concepts. Am Heart J. 1981 Sep; 102(3 Pt 2):500-8. PMID: 7023220.
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    143. Ishida T, Chou MC, Lewis RM, Hartley CJ, Entman M, Field JB. The effect of tolbutamide and hepatic extraction of insulin and glucagon and hepatic glucose output in anesthetized dogs. Endocrinology. 1981 Aug; 109(2):443-50. PMID: 7018888.
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    144. Pinsky WW, Lewis RM, McMillin-Wood JB, Hara H, Hartley CJ, Gillette PC, Entman ML. Myocardial protection from ischemic arrest: potassium and verapamil cardioplegia. Am J Physiol. 1981 Mar; 240(3):H326-35. PMID: 7212077.
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    145. Gibson R, Driscoll D, Gillette P, Hartley C, Entman ML. The comparative electrophysiologic and hemodynamic effects of verapamil in puppies and adult dogs. Dev Pharmacol Ther. 1981; 2(2):104-16. PMID: 7472105.
      View in: PubMed
    146. Driscoll DJ, Fukushige J, Hartley CJ, Lewis RM, Entman ML. The comparative hemodynamic effects of isoproterenol in chronically instrumented puppies and adult dogs. Dev Pharmacol Ther. 1981; 2(2):91-103. PMID: 7472110.
      View in: PubMed
    147. Greene ER, Blair WF, Hartley C. Noninvasive pulsed Doppler blood velocity measurements and calculated flow in human digital arteries. ISA Trans. 1981; 20(2):15-24. PMID: 7275568.
      View in: PubMed
    148. Greene ER, Blair WF, Hartley C. Noninvasive pulsed Doppler blood velocity measurements and calculated flow in human digital arteries. Biomed Sci Instrum. 1980 Apr 21-22; 16:93-105. PMID: 6447521.
      View in: PubMed
    149. Eldridge MW, Greene ER, Miranda FG, Hartley CJ. Noninvasive pulse Doppler blood velocity measurement in the human frontal arteries. Biomed Sci Instrum. 1980 Apr 21-22; 16:67-74. PMID: 7407308.
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    150. Pinsky WW, Lewis RM, Hartley CJ, Entman ML. Permanent changes of ventricular contractility and compliance in chronic volume overload. Am J Physiol. 1979 Nov; 237(5):H575-83. PMID: 40438.
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    151. Driscoll DJ, Gillette PC, Lewis RM, Hartley CJ, Schwartz A. Comparative hemodynamic effects of isoproterenol, dopamine, and dobutamine in the newborn dog. Pediatr Res. 1979 Sep; 13(9):1006-9. PMID: 503650.
      View in: PubMed
    152. Freed D, Hartley CJ, Christman KD, Lyman RC, Agris J, Walker WF. High-frequency pulsed Doppler ultrasound: a new tool for microvascular surgery. J Microsurg. 1979 Sep-Oct; 1(2):148-53. PMID: 16320429.
      View in: PubMed
    153. Eldridge M, Greene ER, Berman W, Hartley C, Yabek S. Ultrasonic pulsed Doppler characterization of the human neonatal peripheral circulation. Biomed Sci Instrum. 1979 Apr 23-25; 15:77-90. PMID: 454797.
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    154. Wood JM, Hanley HG, Entman ML, Hartley CJ, Swain JA, Busch U, Chang CH, Lewis RM, Morgan WJ, Schwartz A. Biochemical and morphological correlates of acute experimental myocardial ischemia in the dog. IV. Energy mechanisms during very early ischemia. Circ Res. 1979 Jan; 44(1):52-61. PMID: 758232.
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    155. Hartley CJ, Hanley HG, Lewis RM, Cole JS. Synchronized pulsed Doppler blood flow and ultrasonic dimension measurement in conscious dogs. Ultrasound Med Biol. 1978; 4(2):99-110. PMID: 734798.
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    156. Hanley HG, Swain JA, Hartley CJ, Lewis RM, Dunn F, Schwartz A. Effects of ionophore RO 2-2985 (X537 A) on conscious dogs in experimentally induced hemorrhagic hypotension. Mortality, systemic pressure and renal and coronary blood flow. Am J Cardiol. 1978 Jan; 41(1):63-8. PMID: 623007.
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    157. Cole JS, Hartley CJ. The pulsed Doppler coronary artery catheter preliminary report of a new technique for measuring rapid changes in coronary artery flow velocity in man. Circulation. 1977 Jul; 56(1):18-25. PMID: 862168.
      View in: PubMed
    158. Hanley HG, Lewis RM, Hartley CJ, Franklin D, Schwartz A. Effects of an inotropic agent, RO 2-2985 (X-537A), on regional blood flow and myocardial function in chronically instrumented conscious dogs and anesthetized dogs. Circ Res. 1975 Aug; 37(2):215-25. PMID: 1149196.
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    159. Hartley CJ, Cole JS. An ultrasonic pulsed Doppler system for measuring blood flow in small vessels. J Appl Physiol. 1974 Oct; 37(4):626-9. PMID: 4411990.
      View in: PubMed
    160. Hartley CJ, Cole JS. A single-crystal ultrasonic catheter-tip velocity probe. Med Instrum. 1974 Jul-Aug; 8(4):241-3. PMID: 4850307.
      View in: PubMed
    161. Hartley CJ, Strandness DE. The effects of atherosclerosis on the transmission of ultrasound. J Surg Res. 1969 Oct; 9(10):575-82. PMID: 5005678.
      View in: PubMed
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