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BILL R BRINKLEY

TitleDean Emeritus
InstitutionBaylor College of Medicine
DepartmentGraduate School of Biomedical Sciences
AddressOne Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleDean Emeritus
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Brinkley WB. Romancing mitosis and the mitotic apparatus. Mol Biol Cell. 2014 Nov 1; 25(21):3270-2. PMID: 25360048; PMCID: PMC4214772.
    2. Brinkley BR. Mitotic checkpoints, MUGs and kinetochores. Cell Cycle. 2013 Jun 15; 12(12):1822-3. PMID: 23759568; PMCID: PMC3735692.
    3. Earnshaw WC, Allshire RC, Black BE, Bloom K, Brinkley BR, Brown W, Cheeseman IM, Choo KH, Copenhaver GP, Deluca JG, Desai A, Diekmann S, Erhardt S, Fitzgerald-Hayes M, Foltz D, Fukagawa T, Gassmann R, Gerlich DW, Glover DM, Gorbsky GJ, Harrison SC, Heun P, Hirota T, Jansen LE, Karpen G, Kops GJ, Lampson MA, Lens SM, Losada A, Luger K, Maiato H, Maddox PS, Margolis RL, Masumoto H, McAinsh AD, Mellone BG, Meraldi P, Musacchio A, Oegema K, O'Neill RJ, Salmon ED, Scott KC, Straight AF, Stukenberg PT, Sullivan BA, Sullivan KF, Sunkel CE, Swedlow JR, Walczak CE, Warburton PE, Westermann S, Willard HF, Wordeman L, Yanagida M, Yen TJ, Yoda K, Cleveland DW. Esperanto for histones: CENP-A, not CenH3, is the centromeric histone H3 variant. Chromosome Res. 2013 Apr; 21(2):101-6. PMID: 23580138; PMCID: PMC3627038.
    4. Slattery SD, Newberg JY, Szafran AT, Hall RM, Brinkley BR, Mancini MA. A framework for image-based classification of mitotic cells in asynchronous populations. Assay Drug Dev Technol. 2012 Apr; 10(2):161-78. PMID: 22084958; PMCID: PMC3323936.
    5. Slattery SD, Mancini MA, Brinkley BR, Hall RM. Aurora-C kinase supports mitotic progression in the absence of Aurora-B. Cell Cycle. 2009 Sep 15; 8(18):2984-94. PMID: 19713763.
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    6. Brinkley BR. Cell motility and the cytoskeleton in transition. Cell Motil Cytoskeleton. 2009 Aug; 66(8):423-4. PMID: 19593800.
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    7. Katayama H, Sasai K, Kloc M, Brinkley BR, Sen S. Aurora kinase-A regulates kinetochore/chromatin associated microtubule assembly in human cells. Cell Cycle. 2008 Sep 1; 7(17):2691-704. PMID: 18773538.
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    8. Slattery SD, Moore RV, Brinkley BR, Hall RM. Aurora-C and Aurora-B share phosphorylation and regulation of CENP-A and Borealin during mitosis. Cell Cycle. 2008 Mar 15; 7(6):787-95. PMID: 18239465.
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    9. Caulin C, Nguyen T, Lang GA, Goepfert TM, Brinkley BR, Cai WW, Lozano G, Roop DR. An inducible mouse model for skin cancer reveals distinct roles for gain- and loss-of-function p53 mutations. J Clin Invest. 2007 Jul; 117(7):1893-901. PMID: 17607363; PMCID: PMC1904325.
    10. MacCorkle RA, Slattery SD, Nash DR, Brinkley BR. Intracellular protein binding to asbestos induces aneuploidy in human lung fibroblasts. Cell Motil Cytoskeleton. 2006 Oct; 63(10):646-57. PMID: 16937396.
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    11. Nishino M, Kurasawa Y, Evans R, Lin SH, Brinkley BR, Yu-Lee LY. NudC is required for Plk1 targeting to the kinetochore and chromosome congression. Curr Biol. 2006 Jul 25; 16(14):1414-21. PMID: 16860740.
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    12. Brinkley BR. Elusive nucleoskeleton visualized in live cells. Cell Motil Cytoskeleton. 2004 Oct; 59(2):119. PMID: 15362115.
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    13. Stenoien DL, Sen S, Mancini MA, Brinkley BR. Dynamic association of a tumor amplified kinase, Aurora-A, with the centrosome and mitotic spindle. Cell Motil Cytoskeleton. 2003 Jun; 55(2):134-46. PMID: 12740874.
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    14. Ouspenski II, Van Hooser AA, Brinkley BR. Relevance of histone acetylation and replication timing for deposition of centromeric histone CENP-A. Exp Cell Res. 2003 May 1; 285(2):175-88. PMID: 12706113.
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    15. Gregson HC, Van Hooser AA, Ball AR, Brinkley BR, Yokomori K. Localization of human SMC1 protein at kinetochores. Chromosome Res. 2002; 10(4):267-77. PMID: 12199140.
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    16. MacCorkle-Chosnek RA, VanHooser A, Goodrich DW, Brinkley BR, Tan TH. Cell cycle regulation of c-Jun N-terminal kinase activity at the centrosomes. Biochem Biophys Res Commun. 2001 Nov 23; 289(1):173-80. PMID: 11708796.
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    17. Zhou G, Mihindukulasuriya KA, MacCorkle-Chosnek RA, Van Hooser A, Hu MC, Brinkley BR, Tan TH. Protein phosphatase 4 is involved in tumor necrosis factor-alpha-induced activation of c-Jun N-terminal kinase. J Biol Chem. 2002 Feb 22; 277(8):6391-8. PMID: 11698396.
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    18. Cabello OA, Eliseeva E, He WG, Youssoufian H, Plon SE, Brinkley BR, Belmont JW. Cell cycle-dependent expression and nucleolar localization of hCAP-H. Mol Biol Cell. 2001 Nov; 12(11):3527-37. PMID: 11694586; PMCID: PMC60273.
    19. Van Hooser AA, Ouspenski II, Gregson HC, Starr DA, Yen TJ, Goldberg ML, Yokomori K, Earnshaw WC, Sullivan KF, Brinkley BR. Specification of kinetochore-forming chromatin by the histone H3 variant CENP-A. J Cell Sci. 2001 Oct; 114(Pt 19):3529-42. PMID: 11682612.
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    20. Brinkley BR. Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol. 2001 Jan; 11(1):18-21. PMID: 11146294.
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    21. Goepfert TM, McCarthy M, Kittrell FS, Stephens C, Ullrich RL, Brinkley BR, Medina D. Progesterone facilitates chromosome instability (aneuploidy) in p53 null normal mammary epithelial cells. FASEB J. 2000 Nov; 14(14):2221-9. PMID: 11053243.
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    22. Go C, He W, Zhong L, Li P, Huang J, Brinkley BR, Wang XJ. Aberrant cell cycle progression contributes to the early-stage accelerated carcinogenesis in transgenic epidermis expressing the dominant negative TGFbetaRII. Oncogene. 2000 Jul 27; 19(32):3623-31. PMID: 10951568.
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    23. Ouspenski II, Cabello OA, Brinkley BR. Chromosome condensation factor Brn1p is required for chromatid separation in mitosis. Mol Biol Cell. 2000 Apr; 11(4):1305-13. PMID: 10749931; PMCID: PMC14848.
    24. Goepfert TM, Brinkley BR. The centrosome-associated Aurora/Ipl-like kinase family. Curr Top Dev Biol. 2000; 49:331-42. PMID: 11005026.
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    25. Van Hooser AA, Mancini MA, Allis CD, Sullivan KF, Brinkley BR. The mammalian centromere: structural domains and the attenuation of chromatin modeling. FASEB J. 1999 Dec; 13 Suppl 2:S216-20. PMID: 10619130.
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    26. Ouspenski II, Elledge SJ, Brinkley BR. New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. Nucleic Acids Res. 1999 Aug 1; 27(15):3001-8. PMID: 10454593; PMCID: PMC148523.
    27. McNeil RS, Swann JW, Brinkley BR, Clark GD. Neuronal cytoskeletal alterations evoked by a platelet-activating factor (PAF) analogue. Cell Motil Cytoskeleton. 1999; 43(2):99-113. PMID: 10379835.
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    28. Van Hooser A, Goodrich DW, Allis CD, Brinkley BR, Mancini MA. Histone H3 phosphorylation is required for the initiation, but not maintenance, of mammalian chromosome condensation. J Cell Sci. 1998 Dec; 111 ( Pt 23):3497-506. PMID: 9811564.
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    29. Kapoor M, Montes de Oca Luna R, Liu G, Lozano G, Cummings C, Mancini M, Ouspenski I, Brinkley BR, May GS. The cenpB gene is not essential in mice. Chromosoma. 1998 Dec; 107(8):570-6. PMID: 9933410.
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    30. Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Brinkley BR, Roop DR. Analysis of centrosome abnormalities and angiogenesis in epidermal-targeted p53172H mutant and p53-knockout mice after chemical carcinogenesis: evidence for a gain of function. Mol Carcinog. 1998 Nov; 23(3):185-92. PMID: 9833779.
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    31. Zhou H, Kuang J, Zhong L, Kuo WL, Gray JW, Sahin A, Brinkley BR, Sen S. Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation. Nat Genet. 1998 Oct; 20(2):189-93. PMID: 9771714.
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    32. Cabello OA, Brinkley BR, Youssoufian H, Belmont JW. Genomic stability and the mechanisms of chromatid separation in mammalian cells. Mol Genet Metab. 1998 Oct; 65(2):105-12. PMID: 9787102.
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    33. Wang XJ, Greenhalgh DA, Jiang A, He D, Zhong L, Medina D, Brinkley BR, Roop DR. Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene. 1998 Jul 9; 17(1):35-45. PMID: 9671312.
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    34. He D, Zeng C, Woods K, Zhong L, Turner D, Busch RK, Brinkley BR, Busch H. CENP-G: a new centromeric protein that is associated with the alpha-1 satellite DNA subfamily. Chromosoma. 1998 Jun; 107(3):189-97. PMID: 9639657.
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    35. Brinkley BR, Goepfert TM. Supernumerary centrosomes and cancer: Boveri's hypothesis resurrected. Cell Motil Cytoskeleton. 1998; 41(4):281-8. PMID: 9858153.
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    36. Hendzel MJ, Wei Y, Mancini MA, Van Hooser A, Ranalli T, Brinkley BR, Bazett-Jones DP, Allis CD. Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation. Chromosoma. 1997 Nov; 106(6):348-60. PMID: 9362543.
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    37. Wise DA, Brinkley BR. Mitosis in cells with unreplicated genomes (MUGs): spindle assembly and behavior of centromere fragments. Cell Motil Cytoskeleton. 1997; 36(3):291-302. PMID: 9067624.
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    38. He D, Brinkley BR. Structure and dynamic organization of centromeres/prekinetochores in the nucleus of mammalian cells. J Cell Sci. 1996 Nov; 109 ( Pt 11):2693-704. PMID: 8937987.
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    39. Mancini MA, He D, Ouspenski II, Brinkley BR. Dynamic continuity of nuclear and mitotic matrix proteins in the cell cycle. J Cell Biochem. 1996 Aug; 62(2):158-64. PMID: 8844395.
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    40. Murti KG, He DC, Brinkley BR, Scott R, Lee SH. Dynamics of human replication protein A subunit distribution and partitioning in the cell cycle. Exp Cell Res. 1996 Mar 15; 223(2):279-89. PMID: 8601405.
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    41. Balczon R, Bao L, Zimmer WE, Brown K, Zinkowski RP, Brinkley BR. Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells. J Cell Biol. 1995 Jul; 130(1):105-15. PMID: 7790366; PMCID: PMC2120504.
    42. Ouspenski II, Mueller UW, Matynia A, Sazer S, Elledge SJ, Brinkley BR. Ran-binding protein-1 is an essential component of the Ran/RCC1 molecular switch system in budding yeast. J Biol Chem. 1995 Feb 3; 270(5):1975-8. PMID: 7836422.
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    43. He D, Zeng C, Brinkley BR. Nuclear matrix proteins as structural and functional components of the mitotic apparatus. Int Rev Cytol. 1995; 162B:1-74. PMID: 8557485.
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    44. Zeng C, He D, Berget SM, Brinkley BR. Nuclear-mitotic apparatus protein: a structural protein interface between the nucleoskeleton and RNA splicing. Proc Natl Acad Sci U S A. 1994 Feb 15; 91(4):1505-9. PMID: 8108437; PMCID: PMC43188.
    45. Zeng C, He D, Brinkley BR. Localization of NuMA protein isoforms in the nuclear matrix of mammalian cells. Cell Motil Cytoskeleton. 1994; 29(2):167-76. PMID: 7820866.
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    46. Cristiano RJ, Smith LC, Kay MA, Brinkley BR, Woo SL. Hepatic gene therapy: efficient gene delivery and expression in primary hepatocytes utilizing a conjugated adenovirus-DNA complex. Proc Natl Acad Sci U S A. 1993 Dec 15; 90(24):11548-52. PMID: 8265587; PMCID: PMC48021.
    47. Zalensky AO, Breneman JW, Zalenskaya IA, Brinkley BR, Bradbury EM. Organization of centromeres in the decondensed nuclei of mature human sperm. Chromosoma. 1993 Sep; 102(8):509-18. PMID: 8243163.
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    48. Ouspenski II, Brinkley BR. Centromeric DNA cloned from functional kinetochore fragments in mitotic cells with unreplicated genomes. J Cell Sci. 1993 Jun; 105 ( Pt 2):359-67. PMID: 8408270.
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    49. Brinkley BR, Ouspenski I, Zinkowski RP. Structure and molecular organization of the centromere-kinetochore complex. Trends Cell Biol. 1992 Jan; 2(1):15-21. PMID: 14731633.
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    50. Brinkley BR. Chromosomes, kinetochores and the microtubule connection. Bioessays. 1991 Dec; 13(12):675-81. PMID: 1789785.
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    51. Ortiz M, Bejarano LA, Rendón MC, Martin G, Brinkley BR, Valdivia MM. Monoclonal antibody with specificity to a conserved epitope in the C-terminal domain of histone H1 variants. Cell Struct Funct. 1991 Aug; 16(4):323-31. PMID: 1723660.
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    52. Zinkowski RP, Meyne J, Brinkley BR. The centromere-kinetochore complex: a repeat subunit model. J Cell Biol. 1991 Jun; 113(5):1091-110. PMID: 1828250; PMCID: PMC2289018.
    53. Yen TJ, Compton DA, Wise D, Zinkowski RP, Brinkley BR, Earnshaw WC, Cleveland DW. CENP-E, a novel human centromere-associated protein required for progression from metaphase to anaphase. EMBO J. 1991 May; 10(5):1245-54. PMID: 2022189; PMCID: PMC452779.
    54. Tousson A, Zeng C, Brinkley BR, Valdivia MM. Centrophilin: a novel mitotic spindle protein involved in microtubule nucleation. J Cell Biol. 1991 Feb; 112(3):427-40. PMID: 1991791; PMCID: PMC2288835.
    55. Balczon R, Accavitti MA, Brinkley BR. Identification of a 40 x 10(3) Mr centromere-associated protein in cultured mammalian cells. J Cell Sci. 1990 Dec; 97 ( Pt 4):705-13. PMID: 2077041.
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    56. Simerly C, Balczon R, Brinkley BR, Schatten G. Microinjected centromere [corrected] kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes. J Cell Biol. 1990 Oct; 111(4):1491-504. PMID: 2211822; PMCID: PMC2116227.
    57. Brinkley BR. Centromeres and kinetochores: integrated domains on eukaryotic chromosomes. Curr Opin Cell Biol. 1990 Jun; 2(3):446-52. PMID: 2198897.
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    58. Mole-Bajer J, Bajer AS, Zinkowski RP, Balczon RD, Brinkley BR. Autoantibodies from a patient with scleroderma CREST recognized kinetochores of the higher plant Haemanthus. Proc Natl Acad Sci U S A. 1990 May; 87(9):3599-603. PMID: 2185478; PMCID: PMC53949.
    59. Zinkowski RP, McCune SL, Balczon RD, Rao PN, Brinkley BR. The centromere and aneuploidy: II. Drug induced detachment and fragmentation of kinetochores of mammalian chromosomes. Prog Clin Biol Res. 1990; 340B:223-36. PMID: 2392445.
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    60. Brinkley BR. Toward a structural and molecular definition of the kinetochore. Cell Motil Cytoskeleton. 1990; 16(2):104-9. PMID: 2198111.
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    61. Balczon RD, Brinkley BR. Synthesis of azidotubulin: a photoaffinity label for tubulin-binding proteins. Biochemistry. 1989 Oct 17; 28(21):8490-6. PMID: 2605199.
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    62. Tousson A, Alley CD, Sorscher EJ, Brinkley BR, Benos DJ. Immunochemical localization of amiloride-sensitive sodium channels in sodium-transporting epithelia. J Cell Sci. 1989 Jun; 93 ( Pt 2):349-62. PMID: 2559094.
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    63. Zinkowski RP, McCune SL, Balczon RD, Rao PN, Brinkley BR. The centromere and aneuploidy: I. Caffeine-induced detachment and fragmentation of kinetochores of mammalian chromosomes. Prog Clin Biol Res. 1989; 318:43-60. PMID: 2696977.
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    64. Brinkley BR, Zinkowski RP, Mollon WL, Davis FM, Pisegna MA, Pershouse M, Rao PN. Movement and segregation of kinetochores experimentally detached from mammalian chromosomes. Nature. 1988 Nov 17; 336(6196):251-4. PMID: 3057382.
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    65. Lai CN, Gallick GE, Maxwell SA, Brinkley BR, Becker FF. Potassium inhibition of transforming protein P85gag-mos and reversal of the transformed phenotype in 6m2 cells. J Cell Physiol. 1988 Mar; 134(3):445-52. PMID: 2965157.
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    66. Balczon RD, Brinkley BR. Tubulin interaction with kinetochore proteins: analysis by in vitro assembly and chemical cross-linking. J Cell Biol. 1987 Aug; 105(2):855-62. PMID: 3305522; PMCID: PMC2114760.
    67. Wood CM, Timme TL, Hurt MM, Brinkley BR, Ledbetter DH, Moses RE. Transformation of DNA repair-deficient human diploid fibroblasts with a simian virus 40 plasmid. Exp Cell Res. 1987 Apr; 169(2):543-53. PMID: 3030788.
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    68. Wheeler WJ, Hsu TC, Tousson A, Brinkley BR. Mitotic inhibition and chromosome displacement induced by estradiol in Chinese hamster cells. Cell Motil Cytoskeleton. 1987; 7(3):235-47. PMID: 3594578.
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    69. Perry G, Wible L, Brinkley BR. Microtubules are not altered in the dystrophic chicken. Exp Cell Res. 1986 Mar; 163(1):266-72. PMID: 3510888.
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    70. Valdivia MM, Tousson A, Brinkley BR. Human antibodies and their use for the study of chromosome organization. Methods Achiev Exp Pathol. 1986; 12:200-23. PMID: 3515123.
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    71. Brinkley BR, Brenner SL, Hall JM, Tousson A, Balczon RD, Valdivia MM. Arrangements of kinetochores in mouse cells during meiosis and spermiogenesis. Chromosoma. 1986; 94(4):309-17. PMID: 3539554.
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    72. Valdivia MM, Brinkley BR. Isolation of a kinetochore-centromere fraction from HeLa metaphase chromosomes. Methods Enzymol. 1986; 134:268-80. PMID: 3547036.
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    73. Valdivia MM, Brinkley BR. Fractionation and initial characterization of the kinetochore from mammalian metaphase chromosomes. J Cell Biol. 1985 Sep; 101(3):1124-34. PMID: 3897244; PMCID: PMC2113728.
    74. Merry DE, Pathak S, Hsu TC, Brinkley BR. Anti-kinetochore antibodies: use as probes for inactive centromeres. Am J Hum Genet. 1985 Mar; 37(2):425-30. PMID: 3885726; PMCID: PMC1684577.
    75. Nielsen TB, Ferdows MS, Brinkley BR, Field JB. Morphological and biochemical responses of cultured thyroid cells to thyrotropin. Endocrinology. 1985 Feb; 116(2):788-97. PMID: 2578386.
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    76. Brinkley BR. Microtubule organizing centers. Annu Rev Cell Biol. 1985; 1:145-72. PMID: 3916316.
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    77. Liang JC, Brinkley BR. Chemical probes and possible targets for the induction of aneuploidy. Basic Life Sci. 1985; 36:491-505. PMID: 4096703.
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    78. Brinkley BR, Tousson A, Valdivia MM. The kinetochore of mammalian chromosomes: structure and function in normal mitosis and aneuploidy. Basic Life Sci. 1985; 36:243-67. PMID: 3913415.
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    79. Anderson DC, Schmalstieg FC, Arnaout MA, Kohl S, Tosi MF, Dana N, Buffone GJ, Hughes BJ, Brinkley BR, Dickey WD, et al. Abnormalities of polymorphonuclear leukocyte function associated with a heritable deficiency of high molecular weight surface glycoproteins (GP138): common relationship to diminished cell adherence. J Clin Invest. 1984 Aug; 74(2):536-51. PMID: 6746906; PMCID: PMC370506.
    80. Anderson DC, Hughes BJ, Wible LJ, Perry GJ, Smith CW, Brinkley BR. Impaired motility of neonatal PMN leukocytes: relationship to abnormalities of cell orientation and assembly of microtubules in chemotactic gradients. J Leukoc Biol. 1984 Jul; 36(1):1-15. PMID: 6376671.
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    81. Deery WJ, Means AR, Brinkley BR. Calmodulin-microtubule association in cultured mammalian cells. J Cell Biol. 1984 Mar; 98(3):904-10. PMID: 6365929; PMCID: PMC2113150.
    82. Eckert BS, Caputi SE, Brinkley BR. Localization of the centriole and keratin intermediate filaments in PtK1 cells by double immunofluorescence. Cell Motil. 1984; 4(4):241-7. PMID: 6206954.
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    83. Brinkley BR, Valdivia MM, Tousson A, Brenner SL. Compound kinetochores of the Indian muntjac. Evolution by linear fusion of unit kinetochores. Chromosoma. 1984; 91(1):1-11. PMID: 6525895.
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    84. Cabral F, Wible L, Brenner S, Brinkley BR. Taxol-requiring mutant of Chinese hamster ovary cells with impaired mitotic spindle assembly. J Cell Biol. 1983 Jul; 97(1):30-9. PMID: 6134737; PMCID: PMC2112497.
    85. Deery WJ, Brinkley BR. Cytoplasmic microtubule assembly-disassembly from endogenous tubulin in a Brij-lysed cell model. J Cell Biol. 1983 Jun; 96(6):1631-41. PMID: 6304113; PMCID: PMC2112452.
    86. Beall PT, Brinkley BR, Chang DC, Hazlewood CF. Microtubule complexes correlated with growth rate and water proton relaxation times in human breast cancer cells. Cancer Res. 1982 Oct; 42(10):4124-30. PMID: 7049356.
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    87. Brenner SL, Brinkley BR. Tubulin assembly sites and the organization of microtubule arrays in mammalian cells. Cold Spring Harb Symp Quant Biol. 1982; 46 Pt 1:241-54. PMID: 6125294.
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    88. Brinkley BR. The cytoskeleton: a perspective. Methods Cell Biol. 1982; 24:1-8. PMID: 7201561.
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    89. Zimmer DB, Turner DS, Goldstein MA, Brinkley BR. A quantitative ultrastructural study of microtubules in transformed and nontransformed cells in vitro. Cell Biol Int Rep. 1981 Dec; 5(12):1115-25. PMID: 7326754.
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    90. Brenner S, Pepper D, Berns MW, Tan E, Brinkley BR. Kinetochore structure, duplication, and distribution in mammalian cells: analysis by human autoantibodies from scleroderma patients. J Cell Biol. 1981 Oct; 91(1):95-102. PMID: 7298727; PMCID: PMC2111947.
    91. Brown RL, Horn JP, Wible L, Arlinghaus RB, Brinkley BR. Sequence of events in the transformation process in cells infected with a temperature-sensitive transformation mutant of Moloney murine sarcoma virus. Proc Natl Acad Sci U S A. 1981 Sep; 78(9):5593-7. PMID: 6946495; PMCID: PMC348797.
    92. Brinkley BR, Cox SM, Pepper DA, Wible L, Brenner SL, Pardue RL. Tubulin assembly sites and the organization of cytoplasmic microtubules in cultured mammalian cells. J Cell Biol. 1981 Sep; 90(3):554-62. PMID: 7026576; PMCID: PMC2111901.
    93. Pardue RL, Kaetzel MA, Hahn SH, Brinkley BR, Dedman JR. The identification of calmodulin-binding sites on mitochondria in cultured 3T3 cells. Cell. 1981 Feb; 23(2):533-42. PMID: 7193532.
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    94. Lasek RJ, Solomon F, Brinkley BR. Which cytoskeletal determinants preserve ontogenetic history? Neurosci Res Program Bull. 1981 Feb; 19(1):125-35. PMID: 7193815.
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    95. Brinkley BR, Beall PT, Wible LJ, Mace ML, Turner DS, Cailleau RM. Variations in cell form and cytoskeleton in human breast carcinoma cells in vitro. Cancer Res. 1980 Sep; 40(9):3118-29. PMID: 7000337.
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    96. Asch BB, Medina D, Kretzer F, Connolly JL, Brinkley BR. Comparative responses of normal and malignant mouse mammary cells to modulation of surface properties. Cancer Res. 1980 Jul; 40(7):2383-9. PMID: 6248204.
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    97. Brown RL, Wible LJ, Brinkley BR. Cytoplasmic microtubule assembly-disassembly in enucleated cells and regenerating karyoplasts. Cell Biol Int Rep. 1980 May; 4(5):453-8. PMID: 6156770.
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    98. Brinkley BR, Wible LJ, Asch BB, Medina D, Mace MM, Beall PT, Cailleau RM. The microtubule cytoskeleton in normal and transformed cells in vitro. Results Probl Cell Differ. 1980; 11:132-8. PMID: 7003669.
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    99. Brinkley BR, Cox SM, Pepper DA. Structure of the mitotic apparatus and chromosomes after hypotonic treatment of mammalian cells in vitro. Cytogenet Cell Genet. 1980; 26(2-4):165-74. PMID: 6993107.
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    100. Pepper DA, Brinkley BR. Tubulin nucleation and assembly in mitotic cells: evidence for nucleic acids in kinetochores and centrosomes. Cell Motil. 1980; 1(1):1-15. PMID: 6184168.
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    101. Brinkley BR, Fistel SH, Marcum JM, Pardue RL. Microtubules in cultured cells; indirect immunofluorescent staining with tubulin antibody. Int Rev Cytol. 1980; 63:59-95. PMID: 395133.
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    102. Pepper DA, Brinkley BR. Microtubule initiation at kinetochores and centrosomes in lysed mitotic cells. Inhibition of site-specific nucleation by tubulin antibody. J Cell Biol. 1979 Aug; 82(2):585-91. PMID: 479317; PMCID: PMC2110471.
    103. Welsh MJ, Dedman JR, Brinkley BR, Means AR. Tubulin and calmodulin. Effects of microtubule and microfilament inhibitors on localization in the mitotic apparatus. J Cell Biol. 1979 Jun; 81(3):624-34. PMID: 379022; PMCID: PMC2110392.
    104. Asch BB, Medina D, Brinkley BR. Microtubules and actin-containing filaments of normal, preneoplastic, and neoplastic mouse mammary epithelial cells. Cancer Res. 1979 Mar; 39(3):893-907. PMID: 371792.
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    105. Sunkara PS, Rao PN, Nishioka K, Brinkley BR. Role of polyamines in cytokinesis of mammalian cells. Exp Cell Res. 1979 Mar 1; 119(1):63-8. PMID: 570113.
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    106. Nicklas RB, Brinkley BR, Pepper DA, Kubai DF, Rickards GK. Electron microscopy of spermatocytes previously studied in life: methods and some observations on micromanipulated chromosomes. J Cell Sci. 1979 Feb; 35:87-104. PMID: 370131.
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    107. Dedman JR, Brinkley BR, Means AR. Regulation of microfilaments and microtubules by calcium and cyclic AMP. Adv Cyclic Nucleotide Res. 1979; 11:131-74. PMID: 227246.
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    108. Brinkley BR, Cox SM. Double fluorescent staining for the separate demonstration of chromosomes and microtubules in mitotic cells in vitro. Stain Technol. 1978 Nov; 53(6):345-9. PMID: 89722.
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    109. Welsh MJ, Dedman JR, Brinkley BR, Means AR. Calcium-dependent regulator protein: localization in mitotic apparatus of eukaryotic cells. Proc Natl Acad Sci U S A. 1978 Apr; 75(4):1867-71. PMID: 273915; PMCID: PMC392442.
    110. Brinkley BR, Fuller GM. Tubulin and actin immunofluorescence as an aid in detecting cell transformation in vitro. Tex Rep Biol Med. 1978; 37:26-44. PMID: 380045.
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    111. Miller CL, Fuseler JW, Brinkley BR. Cytoplasmic microtubules in transformed mouse x nontransformed human cell hybrids: correlation with in vitro growth. Cell. 1977 Sep; 12(1):319-31. PMID: 332382.
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    112. Pepper DA, Brinkley BR. Localization of tubulin in the mitotic apparatus of mammalian cells by immunofluorescence and immunoelectron microscopy. Chromosoma. 1977 Apr 19; 60(3):223-35. PMID: 322970.
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    113. McGill M, Highfield DP, Monahan TM, Brinkley BR. Effects of nucleic acid specific dyes on centrioles of mammalian cells. J Ultrastruct Res. 1976 Oct; 57(1):43-53. PMID: 978782.
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    114. Barham SS, Brinkley BR. Action of rotenone and related respiratory inhibitors on mammalian cell division. 2 Ultrastructural studies. Cytobios. 1976; 15(58-59):97-109. PMID: 1001025.
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    115. Barham SS, Brinkley BR. Action of rotenone and related respiratory inhibitors on mammalian cell division. 1 Cell kinetics and biochemical aspects. Cytobios. 1976; 15(58-59):85-96. PMID: 1001024.
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    116. Fuller GM, Brinkley BR. Structure and control of assembly of cytoplasmic microtubules in normal and transformed cells. J Supramol Struct. 1976; 5(4):497(349)-514(366). PMID: 800619.
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    117. Brinkley BR, Fuller EM, Highfield DP. Cytoplasmic microtubules in normal and transformed cells in culture: analysis by tubulin antibody immunofluorescence. Proc Natl Acad Sci U S A. 1975 Dec; 72(12):4981-5. PMID: 174086; PMCID: PMC388858.
    118. McGill M, Brinkley BR. Human chromosomes and centrioles as nucleating sites for the in vitro assembly of microtubules from bovine brain tubulin. J Cell Biol. 1975 Oct; 67(1):189-99. PMID: 809450; PMCID: PMC2109587.
    119. Brinkley BR, Cartwright J. Cold-labile and cold-stable microtubules in the mitotic spindle of mammalian cells. Ann N Y Acad Sci. 1975 Jun 30; 253:428-39. PMID: 1056753.
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    120. Fuller GM, Brinkley BR, Boughter JM. Immunofluorescence of mitotic spindles by using monospecific antibody against bovine brain tubulin. Science. 1975 Mar 14; 187(4180):948-50. PMID: 1096300.
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    121. Brinkley BR, Hittelman WN. Ultrastructure of mammalian chromosome aberrations. Int Rev Cytol. 1975; 42:49-101. PMID: 53216.
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    122. Brinkley BR, Barham SS, Barranco SC, Fuller GM. Rotenone inhibition of spindle microtubule assembly in mammalian cells. Exp Cell Res. 1974 Mar 30; 85(1):41-6. PMID: 4857086.
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    123. Brinkley BR, Rao PN. Nitrous oxide: effects on the mitotic apparatus and chromosome movement in HeLa cells. J Cell Biol. 1973 Jul; 58(1):96-106. PMID: 4726309; PMCID: PMC2109015.
    124. Mace ML, Tevethia SS, Brinkley BR. Differential immunofluorescent labeling of chromosomes with antisera specific for single strand DNA. Exp Cell Res. 1972 Dec; 75(2):521-3. PMID: 4566307.
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    125. Rattner JB, Brinkley BR. Ultrastructure of mammalian spermiogenesis. 3. The organization and morphogenesis of the manchette during rodent spermiogenesis. J Ultrastruct Res. 1972 Nov; 41(3):209-18. PMID: 4636018.
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    126. Brinkley BR, Cartwright J. Ultrastructural analysis of mitotic spindle elongation in mammalian cells in vitro. Direct microtubule counts. J Cell Biol. 1971 Aug; 50(2):416-31. PMID: 4939523; PMCID: PMC2108283.
    127. Rattner JB, Brinkley BR. Ultrastructure of mammalian spermiogenesis. II. Elimination of the nuclear membrane. J Ultrastruct Res. 1971 Jul; 36(1):1-7. PMID: 4998636.
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    128. Hsu TC, Cooper JE, Mace ML, Brinkley BR. Arrangement of centromeres in mouse cells. Chromosoma. 1971; 34(1):73-87. PMID: 4105528.
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    129. Humphrey RM, Brinkley BR. Ultrastructural studies of radiation-induced chromosome damage. J Cell Biol. 1969 Sep; 42(3):745-53. PMID: 4895598; PMCID: PMC2107714.
    130. Brinkley BR, Stubblefield E, Hsu TC. The effects of colcemid inhibition and reversal on the fine structure of the mitotic apparatus of Chinese hamster cells in vitro. J Ultrastruct Res. 1967 Jul; 19(1):1-18. PMID: 5339063.
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    131. Hsu TC, Brinkley BR, Arrighi FE. The structure and behavior of the nucleolus organizer in mammalian cells. Chromosoma. 1967; 23(2):137-53. PMID: 4970485.
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    132. Stubblefield E, Brinkley BR. Cilia formation in Chinese hamster fibroblasts in vitro as a response to colcemid treatment. J Cell Biol. 1966 Sep; 30(3):645-52. PMID: 5971010; PMCID: PMC2107012.
    133. Brinkley BR, Stubblefield E. The fine structure of the kinetochore of a mammalian cell in vitro. Chromosoma. 1966; 19(1):28-43. PMID: 5912064.
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    134. Brinkley BR. The fine structure of the nucleolus in mitotic divisions of Chinese hamster cells in vitro. J Cell Biol. 1965 Nov; 27(2):411-22. PMID: 5884631; PMCID: PMC2106730.
    135. Hsu TC, Arrighi FE, Klevecz RR, Brinkley BR. The nucleoli in mitotic divisions of mammalian cells in vitro. J Cell Biol. 1965 Aug; 26(2):539-53. PMID: 4222282; PMCID: PMC2106756.
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