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JAMES L POOL

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address6565 Fannin
HOUSTON TX 77030
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    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pharmacology
    DivisionPharmacology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Taylor AA, Pool JL. Clinical role of direct renin inhibition in hypertension. Am J Ther. 2012 May; 19(3):204-10. PMID: 21317620.
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    2. Perlstein TS, Henry RR, Mather KJ, Rickels MR, Abate NI, Grundy SM, Mai Y, Albu JB, Marks JB, Pool JL, Creager MA. Effect of angiotensin receptor blockade on insulin sensitivity and endothelial function in abdominally obese hypertensive patients with impaired fasting glucose. Clin Sci (Lond). 2012 Feb; 122(4):193-202. PMID: 21861845; PMCID: PMC4566948.
    3. Hyman DJ, Pavlik VN, Greisinger AJ, Chan W, Bayona J, Mansyur C, Simms V, Pool J. Effect of a physician uncertainty reduction intervention on blood pressure in uncontrolled hypertensives--a cluster randomized trial. J Gen Intern Med. 2012 Apr; 27(4):413-9. PMID: 22033742; PMCID: PMC3304039.
    4. Ferdinand KC, Pool J, Weitzman R, Purkayastha D, Townsend R. Peripheral and central blood pressure responses of combination aliskiren/hydrochlorothiazide and amlodipine monotherapy in African American patients with stage 2 hypertension: the ATLAAST trial. J Clin Hypertens (Greenwich). 2011 May; 13(5):366-75. PMID: 21545398.
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    5. Friedewald VE, Bennett JS, Christo JP, Pool JL, Scheiman JM, Simon LS, Strand V, White WB, Williams GW, Roberts WC. AJC Editor's consensus: Selective and nonselective nonsteroidal anti-inflammatory drugs and cardiovascular risk. Am J Cardiol. 2010 Sep 15; 106(6):873-84. PMID: 20816131.
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    6. Pavlik VN, Greisinger AJ, Pool J, Haidet P, Hyman DJ. Does reducing physician uncertainty improve hypertension control?: rationale and methods. Circ Cardiovasc Qual Outcomes. 2009 May; 2(3):257-63. PMID: 20031846; PMCID: PMC2780342.
    7. Pool JL, Glazer R, Crikelair N, Levy D. The role of baseline blood pressure in guiding treatment choice: a secondary analysis of the use of valsartan/hydrochlorothiazide as initial therapy in hypertensive adults in a randomized, double-blind, placebo-controlled trial. Clin Drug Investig. 2009; 29(12):791-802. PMID: 19888785.
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    8. Friedewald VE, Giles TD, Pool JL, Yancy CW, Roberts WC. The Editor's Roundtable: Endothelial dysfunction in cardiovascular disease. Am J Cardiol. 2008 Aug 15; 102(4):418-23. PMID: 18678298.
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    9. Oparil S, Abate N, Chen E, Creager MA, Galet V, Jia G, Julius S, Lerman A, Lyle PA, Pool J, Tershakovec AM. A double-blind, randomized study evaluating losartan potassium monotherapy or in combination with hydrochlorothiazide versus placebo in obese patients with hypertension. Curr Med Res Opin. 2008 Apr; 24(4):1101-14. PMID: 18328120.
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    10. Pool JL. Direct renin inhibition: focus on aliskiren. J Manag Care Pharm. 2007 Oct; 13(8 Suppl B):21-33. PMID: 17970614.
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    11. Pool JL, Schmieder RE, Azizi M, Aldigier JC, Januszewicz A, Zidek W, Chiang Y, Satlin A. Aliskiren, an orally effective renin inhibitor, provides antihypertensive efficacy alone and in combination with valsartan. Am J Hypertens. 2007 Jan; 20(1):11-20. PMID: 17198906.
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    12. Pool JL, Glazer R, Weinberger M, Alvarado R, Huang J, Graff A. Comparison of valsartan/hydrochlorothiazide combination therapy at doses up to 320/25 mg versus monotherapy: a double-blind, placebo-controlled study followed by long-term combination therapy in hypertensive adults. Clin Ther. 2007 Jan; 29(1):61-73. PMID: 17379047.
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    13. Friedewald VE, Jones PH, Kaplan NM, Pool JL, Roberts WC. The editor's roundtable: concurrent hypertension and dyslipidemia. Am J Cardiol. 2007 Jan 1; 99(1):134-44. PMID: 17196477.
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    14. Wieles B, Pool J, Wilke M, Weber M, Kolb HJ, Bontrop RE, Goulmy E. The diallelic locus encoding the minor histocompatibility antigen HA-1 is evolutionarily conserved. Tissue Antigens. 2006 Jul; 68(1):62-5. PMID: 16774541.
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    15. Taylor AA, Pool JL. Clinical pharmacology of antihypertensive therapy. Semin Nephrol. 2005 Jul; 25(4):215-26. PMID: 16202694.
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    16. Pool JL. Is it time to move to multidrug combinations? Am J Hypertens. 2003 Nov; 16(11 Pt 2):36S-40S. PMID: 14625159.
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    17. Pool J, Kaihlanen P, Lewis G, Ginsberg D, Oparil S, Glazer R, Messerli FH. Once-daily treatment of patients with hypertension: a placebo-controlled study of amlodipine and benazepril vs amlodipine or benazepril alone. J Hum Hypertens. 2001 Jul; 15(7):495-8. PMID: 11464260.
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    18. Kloner RA, Weinberger M, Pool JL, Chrysant SG, Prasad R, Harris SM, Zyczynski TM, Leidy NK, Michelson EL. Comparative effects of candesartan cilexetil and amlodipine in patients with mild systemic hypertension. Comparison of Candesartan and Amlodipine for Safety, Tolerability and Efficacy (CASTLE) Study Investigators. Am J Cardiol. 2001 Mar 15; 87(6):727-31. PMID: 11249891.
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    19. Pool JL, Kirby RS. Clinical significance of alpha1-adrenoceptor selectivity in the management of benign prostatic hyperplasia. Int Urol Nephrol. 2001; 33(3):407-12. PMID: 12230262.
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    20. Pool JL. The role of angiotensin II in hypertension and end-organ damage. Int J Clin Pract Suppl. 2000 Aug; (111):4-8. PMID: 15977400.
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    21. Taylor AA, Shepherd AM, Polvino W, Mangoo-Karim R, Ballard K, Sunthornyothin S, Luther RR, Pool JL. Prolonged fenoldopam infusions in patients with mild to moderate hypertension: pharmacodynamic and pharmacokinetic effects. Am J Hypertens. 1999 Sep; 12(9 Pt 1):906-14. PMID: 10509549.
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    22. Taylor AA, Mangoo-Karim R, Ballard KD, Luther RR, Pool JL. Sustained hemodynamic effects of the selective dopamine-1 agonist, fenoldopam, during 48-hour infusions in hypertensive patients: a dose-tolerability study. J Clin Pharmacol. 1999 May; 39(5):471-9. PMID: 10234594.
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    23. Pool JL, Glazer R, Chiang YT, Gatlin M. Dose-response efficacy of valsartan, a new angiotensin II receptor blocker. J Hum Hypertens. 1999 Apr; 13(4):275-81. PMID: 10333347.
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    24. Jenkins CD, Miller TQ, Hewitt LO, Wallace JM, Pool JL. A 3-dimensional analysis of modes of cardiovascular adaptation: concepts, methods and preliminary findings. Clin Invest Med. 1998 Dec; 21(6):228-50. PMID: 9885758.
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    25. Pool J, Oparil S, Hedner T, Glazer R, Oddou-Stock P, Hester A. Dose-responsive antihypertensive efficacy of valsartan, a new angiotensin II-receptor blocker. Clin Ther. 1998 Nov-Dec; 20(6):1106-14. PMID: 9916605.
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    26. Lacourcière Y, Pool JL, Svetkey L, Gradman AH, Larochelle P, de Champlain J, Smith WB. A randomized, double-blind, placebo-controlled, parallel-group, multicenter trial of four doses of tasosartan in patients with essential hypertension. Tasosartan Investigator's Group. Am J Hypertens. 1998 Apr; 11(4 Pt 1):454-61. PMID: 9607384.
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    27. Pool JL, Guthrie RM, Littlejohn TW, Raskin P, Shephard AM, Weber MA, Weir MR, Wilson TW, Wright J, Kassler-Taub KB, Reeves RA. Dose-related antihypertensive effects of irbesartan in patients with mild-to-moderate hypertension. Am J Hypertens. 1998 Apr; 11(4 Pt 1):462-70. PMID: 9607385.
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    28. Kirby RS, Pool JL. Alpha adrenoceptor blockade in the treatment of benign prostatic hyperplasia: past, present and future. Br J Urol. 1997 Oct; 80(4):521-32. PMID: 9352686.
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    29. Neutel J, Weber M, Pool J, Smith D, Fitzsimmons S, Chiang YT, Gatlin M. Valsartan, a new angiotensin II antagonist: antihypertensive effects over 24 hours. Clin Ther. 1997 May-Jun; 19(3):447-58; discussion 367-8. PMID: 9220209.
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    30. Pool JL, Cushman WC, Saini RK, Nwachuku CE, Battikha JP. Use of the factorial design and quadratic response surface models to evaluate the fosinopril and hydrochlorothiazide combination therapy in hypertension. Am J Hypertens. 1997 Jan; 10(1):117-23. PMID: 9008256.
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    31. Pool JL. Doxazosin: a new approach to hypertension and benign prostatic hyperplasia. Br J Clin Pract. 1996 Apr-May; 50(3):154-63. PMID: 8733335.
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    32. Lenz ML, Pool JL, Laddu AR, Varghese A, Johnston W, Taylor AA. Combined terazosin and verapamil therapy in essential hypertension. Hemodynamic and pharmacokinetic interactions. Am J Hypertens. 1995 Feb; 8(2):133-45. PMID: 7755941.
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    33. Bradford RH, Shear CL, Chremos AN, Dujovne CA, Franklin FA, Grillo RB, Higgins J, Langendorfer A, Nash DT, Pool JL, et al. Expanded Clinical Evaluation of Lovastatin (EXCEL) study results: two-year efficacy and safety follow-up. Am J Cardiol. 1994 Oct 1; 74(7):667-73. PMID: 7942524.
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    34. Pool JL. Role of the sympathetic nervous system in hypertension and benign prostatic hyperplasia. Br J Clin Pract Suppl. 1994 May; 74:13-7. PMID: 7519436.
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    35. Pool JL. Effects of doxazosin on coronary heart disease risk factors in the hypertensive patient. Br J Clin Pract Suppl. 1994 May; 74:8-12. PMID: 8049119.
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    36. Ciampricotti R, Deckers JW, Taverne R, el Gamal M, Relik-van Wely L, Pool J. Characteristics of conditioned and sedentary men with acute coronary syndromes. Am J Cardiol. 1994 Feb 1; 73(4):219-22. PMID: 8296749.
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    37. Black HR, Chrysant SG, Curry CL, Frishman WH, Grimm RH, Lasseter KC, Okun R, Pool JL, Raizada V, Vlachakis ND, et al. Antihypertensive and metabolic effects of concomitant administration of terazosin and methyclothiazide for the treatment of essential hypertension. J Clin Pharmacol. 1992 Apr; 32(4):351-9. PMID: 1349028.
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    38. Pool JL, Shear CL, Downton M, Schnaper H, Stinnett S, Dujovne C, Bradford RH, Chremos AN. Lovastatin and coadministered antihypertensive/cardiovascular agents. Hypertension. 1992 Mar; 19(3):242-8. PMID: 1347757.
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    39. Pool JL. Combination antihypertensive therapy with terazosin and other antihypertensive agents: results of clinical trials. Am Heart J. 1991 Sep; 122(3 Pt 2):926-31. PMID: 1678924.
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    40. Bradford RH, Shear CL, Chremos AN, Franklin FA, Nash DT, Hurley DP, Dujovne CA, Pool JL, Schnaper H, Hesney M, et al. Expanded clinical evaluation of lovastatin (EXCEL) study results: III. Efficacy in modifying lipoproteins and implications for managing patients with moderate hypercholesterolemia. Am J Med. 1991 Jul 31; 91(1B):18S-24S. PMID: 1867232.
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    41. Dujovne CA, Chremos AN, Pool JL, Schnaper H, Bradford RH, Shear CL, Higgins J, Downton M, Franklin FA, Nash DT, et al. Expanded clinical evaluation of lovastatin (EXCEL) study results: IV. Additional perspectives on the tolerability of lovastatin. Am J Med. 1991 Jul 31; 91(1B):25S-30S. PMID: 1831006.
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    42. Weir MR, Josselson J, Ekelund LG, Korc M, Pool JL, Stein GH, Wolbach RA, Champion D. Nicardipine as antihypertensive monotherapy: positive effects on quality of life. J Hum Hypertens. 1991 Jun; 5(3):205-13. PMID: 1920344.
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    43. Pool JL. Effects of doxazosin on serum lipids: a review of the clinical data and molecular basis for altered lipid metabolism. Am Heart J. 1991 Jan; 121(1 Pt 2):251-9; discussion 259-60. PMID: 1824647.
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    44. Pool JL. Antihypertensive effect of fosinopril, a new angiotensin converting enzyme inhibitor: findings of the Fosinopril Study Group II. Clin Ther. 1990 Nov-Dec; 12(6):520-33. PMID: 2149674.
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    45. Pool JL, Lenz ML, Taylor AA. Alpha 1-adrenoreceptor blockade and the molecular basis of lipid metabolism alterations. J Hum Hypertens. 1990 Oct; 4 Suppl 3:23-33. PMID: 1979819.
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    46. Bradford RH, Shear CL, Chremos AN, Dujovne C, Franklin FA, Hesney M, Higgins J, Langendörfer A, Pool JL, Schnaper H, et al. Expanded clinical evaluation of lovastatin (EXCEL) study: design and patient characteristics of a double-blind, placebo-controlled study in patients with moderate hypercholesterolemia. Am J Cardiol. 1990 Sep 18; 66(8):44B-55B. PMID: 2206036.
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    47. van Dixhoorn J, Duivenvoorden HJ, Staal HA, Pool J. Physical training and relaxation therapy in cardiac rehabilitation assessed through a composite criterion for training outcome. Am Heart J. 1989 Sep; 118(3):545-52. PMID: 2672755.
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    48. Pool JL, Taylor AA, Nelson EB. Review of the effects of doxazosin, a new selective alpha 1-adrenergic inhibitor, on lipoproteins in patients with essential hypertension. Am J Med. 1989 Aug 16; 87(2A):57S-61S. PMID: 2569825.
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    49. Mallette LE, LeBlanc AD, Pool JL, Mechanick JI. Cyclic therapy of osteoporosis with neutral phosphate and brief, high-dose pulses of etidronate. J Bone Miner Res. 1989 Apr; 4(2):143-8. PMID: 2499164.
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    50. Taylor AA, Davies AO, Mares A, Raschko J, Pool JL, Nelson EB, Mitchell JR. Spectrum of dysautonomia in mitral valvular prolapse. Am J Med. 1989 Mar; 86(3):267-74. PMID: 2919608.
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    51. Crawford ES, Coselli JS, Safi HJ, Martin TD, Pool JL. The impact of renal fusion and ectopia on aortic surgery. J Vasc Surg. 1988 Oct; 8(4):375-83. PMID: 3172375.
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    52. Pool JL, Nelson EB, Taylor AA. Clinical experience and rationale for angiotensin-converting enzyme inhibition with lisinopril as the initial treatment for hypertension in older patients. Am J Med. 1988 Sep 23; 85(3B):19-24. PMID: 2844082.
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    53. Cubeddu LX, Pool JL, Bloomfield R, Klotman PE, Pickering BI, Wombolt DG, Nelson EB, Halperin A. Effect of doxazosin monotherapy on blood pressure and plasma lipids in patients with essential hypertension. Am J Hypertens. 1988 Apr; 1(2):158-67. PMID: 2969740.
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    54. Goldfarb R, Pool JL, Wheeler T. Isolated renal artery dissection secondary to medial degeneration. J Urol. 1988 Feb; 139(2):346-7. PMID: 3339739.
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    55. Pool JL, Nelson EB, Taylor AA, Mitchell JR. Terazosin (Hytrin): cumulative experience of clinical trials in the USA for the treatment of mild to moderate essential hypertension. Br J Clin Pract Suppl. 1987 Dec; 54:9-14. PMID: 2905162.
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    56. Simpson RK, Pool JL, Grossman RG, Rose JE, Taylor AA. Neurosurgical management of carotid sinus hypersensitivity. Report of three cases. J Neurosurg. 1987 Nov; 67(5):757-9. PMID: 3668646.
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    57. Schmedtje JF, Sax S, Pool JL, Goldfarb RA, Nelson EB. Localization of ectopic pheochromocytomas by magnetic resonance imaging. Am J Med. 1987 Oct; 83(4):770-2. PMID: 3674064.
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    58. Pool JL. Plasma lipid lowering effects of doxazosin, a new selective alpha1 adrenergic inhibitor for systemic hypertension. Am J Cardiol. 1987 May 29; 59(14):46G-50G. PMID: 2884853.
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    59. Davies AO, Mares A, Pool JL, Taylor AA. Mitral valve prolapse with symptoms of beta-adrenergic hypersensitivity. Beta 2-adrenergic receptor supercoupling with desensitization on isoproterenol exposure. Am J Med. 1987 Feb; 82(2):193-201. PMID: 3028141.
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    60. Pool JL, Gennari J, Goldstein R, Kochar MS, Lewin AJ, Maxwell MH, McChesney JA, Mehta J, Nash DT, Nelson EB, et al. Controlled multicenter study of the antihypertensive effects of lisinopril, hydrochlorothiazide, and lisinopril plus hydrochlorothiazide in the treatment of 394 patients with mild to moderate essential hypertension. J Cardiovasc Pharmacol. 1987; 9 Suppl 3:S36-42. PMID: 2442550.
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    61. Nelson EB, Pool JL, Taylor AA. Antihypertensive activity of isradipine in humans: a new dihydropyridine calcium channel antagonist. Clin Pharmacol Ther. 1986 Dec; 40(6):694-7. PMID: 2946507.
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    62. Nelson EB, Pool JL, Taylor AA. Pharmacology of angiotensin converting enzyme inhibitors. A review. Am J Med. 1986 Oct 31; 81(4C):13-8. PMID: 3022580.
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    63. Schwartz JB, Taylor A, Abernethy D, O'Meara M, Farmer J, Young J, Nelson E, Pool J, Mitchell JR. Pharmacokinetics and pharmacodynamics of enalapril in patients with congestive heart failure and patients with hypertension. J Cardiovasc Pharmacol. 1985 Jul-Aug; 7(4):767-76. PMID: 2410720.
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    64. Taylor AA, Fennell WH, Ruud CO, Pool JL, Nelson EB, Ginos JZ, Mitchell JR. Propylbutyldopamine. Mechanism of blood pressure lowering in hypertensive patients. Hypertension. 1984 Mar-Apr; 6(2 Pt 2):I40-5. PMID: 6373598.
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    65. Simoons M, Lap C, Pool J. Heart rate levels and ventricular ectopic activity during cardiac rehabilitation. Am Heart J. 1980 Jul; 100(1):9-14. PMID: 7386369.
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    66. Taburet AM, Taylor AA, Mitchell JR, Rollins DE, Pool JL. Plasma concentrations of propranolol and 4-hydroxypropranolol in man measured by high pressure liquid chromatography. Life Sci. 1979 Jan 15; 24(3):209-17. PMID: 423699.
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    67. Taylor AA, Pool JL, Lake CR, Ziegler MG, Rosen RA, Rollins DE, Mitchell JR. Plasma norepinephrine concentrations: no differences among normal volunteers and low, high or normal renin hypertensive patients. Life Sci. 1978 May 1; 22(17):1499-510. PMID: 672409.
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    68. Mitchell JR, Taylor AA, Pool JL, Lake CR, Rollins DE, Bartter FC. Renin-aldosterone profiling in hypertension. Ann Intern Med. 1977 Nov; 87(5):596-312. PMID: 335942.
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    69. Pool JL. Muslin gauze in intracranial vascular surgery. Technical note. J Neurosurg. 1976 Jan; 44(1):127-8. PMID: 1244428.
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    70. Meilink-Hoedemaker LJ, Pool J, Muste-Heijns MM. A double-blind placebo-controlled cross-over study with lidoflazine (Clinium) in post-infarction patients. Acta Med Scand. 1976; 199(1-2):17-23. PMID: 766572.
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    71. Pool JL. Henry L. Heyl, 1906-1975. J Neurosurg. 1975 Jun; 42(6):625-7. PMID: 1095692.
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    72. Pool JL. Bifrontal craniotomy for anterior communicating artery aneurysms. J Neurosurg. 1972 Feb; 36(2):212-20. PMID: 5008735.
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    73. Pool JL. Excision of cerebral arteriovenous malformations. J Neurosurg. 1968 Sep; 29(3):312-21. PMID: 5684412.
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    74. Pool JL. Gliomas in the region of the brain stem. J Neurosurg. 1968 Aug; 29(2):164-7. PMID: 5673314.
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    75. McMurtry JG, Pool JL, Nova HR. The use of rheomacrodex in the surgery of intracranial aneurysms. J Neurosurg. 1967 Feb; 26(2):218-22. PMID: 6018581.
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    76. Pool JL, Colton RP. The dissecting microscope for intracranial vascular surgery. J Neurosurg. 1966 Sep; 25(3):315-8. PMID: 5921324.
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    77. Pool JL. Suboccipital surgery for acoustic neurinomas: advantages and disadvantages. J Neurosurg. 1966 Feb; 24(2):483-92. PMID: 5935378.
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    78. STEIN BM, LEEDS NE, TAVERAS JM, POOL JL. MENINGIOMAS OF THE FORAMEN MAGNUM. J Neurosurg. 1963 Sep; 20:740-51. PMID: 14184992.
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    79. POOL JL. Timing and techniques in the intracranial surgery of ruptured aneurysms of the anterior communicating artery. J Neurosurg. 1962 May; 19:378-88. PMID: 14487836.
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    80. POOL JL, POTANOS JN, KRUEGER EG. Osteomas and mucoceles of the frontal paranasal sinuses. J Neurosurg. 1962 Feb; 19:130-5. PMID: 14487830.
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    81. POOL JL. Treatment of arteriovenous malformations of the cerebral hemispheres. J Neurosurg. 1962 Feb; 19:136-41. PMID: 14487838.
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    82. RANSOHOFF J, POTANOS J, BOSCHENSTEIN F, POOL JL. Total removal of recurrent acoustic tumors. J Neurosurg. 1961 Nov; 18:804-10. PMID: 14490297.
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    83. POOL JL. Aneurysms of the anterior communicating artery. Bifrontal craniotomy and routine use of temporary clips. J Neurosurg. 1961 Jan; 18:98-112. PMID: 13737059.
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    84. POOL JL, KESSLER LA. Mechanism and control of centrally induced cardiac irregularities during hypothermia. I. Clinical observations. J Neurosurg. 1958 Jan; 15(1):52-64. PMID: 13492075.
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    85. POOL JL. Unilateral thoracic hyperhidrosis caused by osteoma of the tenth dorsal vertebra; case report. J Neurosurg. 1956 Jan; 13(1):111-5. PMID: 13286733.
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    86. POOL JL. The visceral brain of man. J Neurosurg. 1954 Jan; 11(1):45-63. PMID: 13131094.
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    87. GLUSMAN M, RANSOHOFF J, POOL JL, GRUNDFEST H, METTLER FA. Electrical excitability of the human motor cortex. I. The parameters of the electrical stimulus. J Neurosurg. 1952 Sep; 9(5):461-71. PMID: 12981568.
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    88. POOL JL, BRABSON JA. Pain in stimulating the distal segment of divided peripheral nerves. J Neurosurg. 1946 Nov; 3(6):468-73. PMID: 20279143.
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    89. SCARFF JE, POOL JL. Factors causing massive spasm following transection of the cord in man. J Neurosurg. 1946 Jul; 3:285-93. PMID: 20989177.
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    90. POOL JL, TURNER OA. Ependymoma of spinal cord; subtotal intramedullary removal from syringomyelic cavity. J Neurosurg. 1946 Jul; 3:348-51. PMID: 20989184.
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    91. POOL JL. Nerve stimulation in paraplegic patients by means of buried induction coil; preliminary report. J Neurosurg. 1946 May; 3:264-7. PMID: 21026951.
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    92. POOL JL. Electrospinogram (ESG); spinal cord action potentials recorded from a paraplegic patient. J Neurosurg. 1946 May; 3:192-8. PMID: 21026940.
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