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DORIT DONOVIEL

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pharmacology
Address6500 Main Street, Suite 910
Houston TX 77030
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Space Medicine
    DivisionCenter for Space Medicine


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Bershad EM, Anand A, DeSantis SM, Yang M, Tang RA, Calvillo E, Malkin-Gosdin L, Foroozan R, Damani R, Maldonado N, Gupta P, Tan B, Venkatasubba Rao CP, Suarez JI, Clark JB, Sutton JP, Donoviel DB. Clinical Validation of a Transcranial Doppler-Based Noninvasive Intracranial Pressure Meter: A Prospective Cross-Sectional Study. World Neurosurg. 2016 May; 89:647-653.e1. PMID: 26724629.
      View in: PubMed
    2. Hiles LA, Donoviel DB, Bershad EM. Noninvasive Brain Physiology Monitoring for Extreme Environments: A Critical Review. J Neurosurg Anesthesiol. 2015 Oct; 27(4):318-28. PMID: 25811362.
      View in: PubMed
    3. Mark S, Scott GB, Donoviel DB, Leveton LB, Mahoney E, Charles JB, Siegel B. The impact of sex and gender on adaptation to space: executive summary. J Womens Health (Larchmt). 2014 Nov; 23(11):941-7. PMID: 25401937; PMCID: PMC4236030.
    4. Brommage R, Desai U, Revelli JP, Donoviel DB, Fontenot GK, Dacosta CM, Smith DD, Kirkpatrick LL, Coker KJ, Donoviel MS, Eberhart DE, Holt KH, Kelly MR, Paradee WJ, Philips AV, Platt KA, Suwanichkul A, Hansen GM, Sands AT, Zambrowicz BP, Powell DR. High-throughput screening of mouse knockout lines identifies true lean and obese phenotypes. Obesity (Silver Spring). 2008 Oct; 16(10):2362-7. PMID: 18719666.
      View in: PubMed
    5. To MD, Gokgoz N, Doyle TG, Donoviel DB, Knight JA, Hyslop PS, Bernstein A, Andrulis IL. Functional characterization of novel presenilin-2 variants identified in human breast cancers. Oncogene. 2006 Jun 15; 25(25):3557-64. PMID: 16474849.
      View in: PubMed
    6. Lai MT, Crouthamel MC, DiMuzio J, Pietrak BL, Donoviel DB, Bernstein A, Gardell SJ, Li YM, Hazuda D. A presenilin-independent aspartyl protease prefers the gamma-42 site cleavage. J Neurochem. 2006 Jan; 96(1):118-25. PMID: 16300640.
      View in: PubMed
    7. Takeda T, Asahi M, Yamaguchi O, Hikoso S, Nakayama H, Kusakari Y, Kawai M, Hongo K, Higuchi Y, Kashiwase K, Watanabe T, Taniike M, Nakai A, Nishida K, Kurihara S, Donoviel DB, Bernstein A, Tomita T, Iwatsubo T, Hori M, Otsu K. Presenilin 2 regulates the systolic function of heart by modulating Ca2+ signaling. FASEB J. 2005 Dec; 19(14):2069-71. PMID: 16204356.
      View in: PubMed
    8. Lai MT, Chen E, Crouthamel MC, DiMuzio-Mower J, Xu M, Huang Q, Price E, Register RB, Shi XP, Donoviel DB, Bernstein A, Hazuda D, Gardell SJ, Li YM. Presenilin-1 and presenilin-2 exhibit distinct yet overlapping gamma-secretase activities. J Biol Chem. 2003 Jun 20; 278(25):22475-81. PMID: 12684521.
      View in: PubMed
    9. Donoho G, Brenneman MA, Cui TX, Donoviel D, Vogel H, Goodwin EH, Chen DJ, Hasty P. Deletion of Brca2 exon 27 causes hypersensitivity to DNA crosslinks, chromosomal instability, and reduced life span in mice. Genes Chromosomes Cancer. 2003 Apr; 36(4):317-31. PMID: 12619154.
      View in: PubMed
    10. Finch RA, Donoviel DB, Potter D, Shi M, Fan A, Freed DD, Wang CY, Zambrowicz BP, Ramirez-Solis R, Sands AT, Zhang N. mdmx is a negative regulator of p53 activity in vivo. Cancer Res. 2002 Jun 1; 62(11):3221-5. PMID: 12036937.
      View in: PubMed
    11. Hitoshi S, Alexson T, Tropepe V, Donoviel D, Elia AJ, Nye JS, Conlon RA, Mak TW, Bernstein A, van der Kooy D. Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells. Genes Dev. 2002 Apr 1; 16(7):846-58. PMID: 11937492; PMCID: PMC186324.
    12. Taniguchi Y, Karlström H, Lundkvist J, Mizutani T, Otaka A, Vestling M, Bernstein A, Donoviel D, Lendahl U, Honjo T. Notch receptor cleavage depends on but is not directly executed by presenilins. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):4014-9. PMID: 11891288; PMCID: PMC122640.
    13. Berechid BE, Kitzmann M, Foltz DR, Roach AH, Seiffert D, Thompson LA, Olson RE, Bernstein A, Donoviel DB, Nye JS. Identification and characterization of presenilin-independent Notch signaling. J Biol Chem. 2002 Mar 8; 277(10):8154-65. PMID: 11756438.
      View in: PubMed
    14. Shiels A, Bassnett S, Varadaraj K, Mathias R, Al-Ghoul K, Kuszak J, Donoviel D, Lilleberg S, Friedrich G, Zambrowicz B. Optical dysfunction of the crystalline lens in aquaporin-0-deficient mice. Physiol Genomics. 2001 Dec 21; 7(2):179-86. PMID: 11773604.
      View in: PubMed
    15. Donoviel DB, Freed DD, Vogel H, Potter DG, Hawkins E, Barrish JP, Mathur BN, Turner CA, Geske R, Montgomery CA, Starbuck M, Brandt M, Gupta A, Ramirez-Solis R, Zambrowicz BP, Powell DR. Proteinuria and perinatal lethality in mice lacking NEPH1, a novel protein with homology to NEPHRIN. Mol Cell Biol. 2001 Jul; 21(14):4829-36. PMID: 11416156; PMCID: PMC87176.
    16. Sato N, Urano F, Yoon Leem J, Kim SH, Li M, Donoviel D, Bernstein A, Lee AS, Ron D, Veselits ML, Sisodia SS, Thinakaran G. Upregulation of BiP and CHOP by the unfolded-protein response is independent of presenilin expression. Nat Cell Biol. 2000 Dec; 2(12):863-70. PMID: 11146649.
      View in: PubMed
    17. Zhang Z, Nadeau P, Song W, Donoviel D, Yuan M, Bernstein A, Yankner BA. Presenilins are required for gamma-secretase cleavage of beta-APP and transmembrane cleavage of Notch-1. Nat Cell Biol. 2000 Jul; 2(7):463-5. PMID: 10878814.
      View in: PubMed
    18. Donoviel DB, Hadjantonakis AK, Ikeda M, Zheng H, Hyslop PS, Bernstein A. Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes Dev. 1999 Nov 1; 13(21):2801-10. PMID: 10557208; PMCID: PMC317124.
    19. Donoviel DB, Bernstein A. SEL-1L maps to human chromosome 14, near the insulin-dependent diabetes mellitus locus 11. Genomics. 1999 Mar 1; 56(2):232-3. PMID: 10051412.
      View in: PubMed
    20. Donoviel DB, Donoviel MS, Fan E, Hadjantonakis A, Bernstein A. Cloning and characterization of Sel-1l, a murine homolog of the C. elegans sel-1 gene. Mech Dev. 1998 Nov; 78(1-2):203-7. PMID: 9858735.
      View in: PubMed
    21. Klüppel M, Donoviel DB, Brunkow ME, Motro B, Bernstein A. Embryonic and adult expression patterns of the Tec tyrosine kinase gene suggest a role in megakaryocytopoiesis, blood vessel development, and melanogenesis. Cell Growth Differ. 1997 Dec; 8(12):1249-56. PMID: 9419413.
      View in: PubMed
    22. Donoviel DB, Shield MA, Buskin JN, Haugen HS, Clegg CH, Hauschka SD. Analysis of muscle creatine kinase gene regulatory elements in skeletal and cardiac muscles of transgenic mice. Mol Cell Biol. 1996 Apr; 16(4):1649-58. PMID: 8657140; PMCID: PMC231151.
    23. Donoviel DB, Amacher SL, Judge KW, Bornstein P. Thrombospondin gene expression is associated with mitogenesis in 3T3 cells: induction by basic fibroblast growth factor. J Cell Physiol. 1990 Oct; 145(1):16-23. PMID: 2211838.
      View in: PubMed
    24. Donoviel DB, Framson P, Eldridge CF, Cooke M, Kobayashi S, Bornstein P. Structural analysis and expression of the human thrombospondin gene promoter. J Biol Chem. 1988 Dec 15; 263(35):18590-3. PMID: 2848801.
      View in: PubMed
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