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ALAN R DAVIS

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
AddressCenter for Cell & Gene Therapy
One Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Cell & Gene Therapy
    DivisionCenter for Cell & Gene Therapy

    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Orthopedic Surgery
    DivisionOrthopedic Surgery


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Davis EL, Sonnet C, Lazard ZW, Henslee G, Gugala Z, Salisbury EA, Strecker EV, Davis TA, Forsberg JA, Davis AR, Olmsted-Davis EA. Location-dependent heterotopic ossification in the rat model: The role of activated matrix metalloproteinase 9. J Orthop Res. 2016 Feb 26. PMID: 26919547.
      View in: PubMed
    2. Davis EL, Salisbury EA, Olmsted-Davis E, Davis AR. Anaplerotic Accumulation of Tricarboxylic Acid Cycle Intermediates as Well as Changes in Other Key Metabolites During Heterotopic Ossification. J Cell Biochem. 2016 Apr; 117(4):1044-53. PMID: 26627193; PMCID: PMC4784167.
    3. Lazard ZW, Olmsted-Davis EA, Salisbury EA, Gugala Z, Sonnet C, Davis EL, Beal E, Ubogu EE, Davis AR. Osteoblasts Have a Neural Origin in Heterotopic Ossification. Clin Orthop Relat Res. 2015 May 6. PMID: 25944403.
      View in: PubMed
    4. Reichel LM, Salisbury E, Moustoukas MJ, Davis AR, Olmsted-Davis E. Molecular mechanisms of heterotopic ossification. J Hand Surg Am. 2014 Mar; 39(3):563-6. PMID: 24246757; PMCID: PMC4091987.
    5. Lu Y, Darne CD, Tan IC, Zhu B, Hall MA, Lazard ZW, Davis AR, Simpson L, Sevick-Muraca EM, Olmsted-Davis EA. Far-red fluorescence gene reporter tomography for determination of placement and viability of cell-based gene therapies. Opt Express. 2013 Oct 7; 21(20):24129-38. PMID: 24104323; PMCID: PMC3796689.
    6. Sonnet C, Simpson CL, Olabisi RM, Sullivan K, Lazard Z, Gugala Z, Peroni JF, Weh JM, Davis AR, West JL, Olmsted-Davis EA. Rapid healing of femoral defects in rats with low dose sustained BMP2 expression from PEGDA hydrogel microspheres. J Orthop Res. 2013 Oct; 31(10):1597-604. PMID: 23832813.
      View in: PubMed
    7. Salisbury EA, Lazard ZW, Ubogu EE, Davis AR, Olmsted-Davis EA. Transient brown adipocyte-like cells derive from peripheral nerve progenitors in response to bone morphogenetic protein 2. Stem Cells Transl Med. 2012 Dec; 1(12):874-85. PMID: 23283549; PMCID: PMC3659676.
    8. Stephens EH, Saltarrelli JG, Balaoing LR, Baggett LS, Nandi I, Anderson KM, Morrisett JD, Reardon MJ, Simpson MA, Weigel PH, Olmsted-Davis EA, Davis AR, Grande-Allen KJ. Hyaluronan turnover and hypoxic brown adipocytic differentiation are co-localized with ossification in calcified human aortic valves. Pathol Res Pract. 2012 Nov 15; 208(11):642-50. PMID: 23017666; PMCID: PMC3496006.
    9. Salisbury E, Hipp J, Olmsted-Davis EA, Davis AR, Heggeness MH, Gannon FH. Histologic identification of brown adipose and peripheral nerve involvement in human atherosclerotic vessels. Hum Pathol. 2012 Dec; 43(12):2213-22. PMID: 22748303; PMCID: PMC3484244.
    10. Mumaw J, Jordan ET, Sonnet C, Olabisi RM, Olmsted-Davis EA, Davis AR, Peroni JF, West JL, West F, Lu Y, Stice SL. Rapid Heterotrophic Ossification with Cryopreserved Poly(ethylene glycol-) Microencapsulated BMP2-Expressing MSCs. Int J Biomater. 2012; 2012:861794. PMID: 22500171; PMCID: PMC3296315.
    11. Salisbury E, Rodenberg E, Sonnet C, Hipp J, Gannon FH, Vadakkan TJ, Dickinson ME, Olmsted-Davis EA, Davis AR. Sensory nerve induced inflammation contributes to heterotopic ossification. J Cell Biochem. 2011 Oct; 112(10):2748-58. PMID: 21678472; PMCID: PMC3329372.
    12. Rodenberg E, Azhdarinia A, Lazard ZW, Hall M, Kwon SK, Wilganowski N, Salisbury EA, Merched-Sauvage M, Olmsted-Davis EA, Sevick-Muraca EM, Davis AR. Matrix metalloproteinase-9 is a diagnostic marker of heterotopic ossification in a murine model. Tissue Eng Part A. 2011 Oct; 17(19-20):2487-96. PMID: 21599541.
      View in: PubMed
    13. Salisbury EA, Olmsted-Davis EA, Davis AR. Adverse events and bone morphogenetic protein-2. Spine J. 2011 Aug; 11(8):802. PMID: 21925422.
      View in: PubMed
    14. Lazard ZW, Heggeness MH, Hipp JA, Sonnet C, Fuentes AS, Nistal RP, Davis AR, Olabisi RM, West JL, Olmsted-Davis EA. Cell-based gene therapy for repair of critical size defects in the rat fibula. J Cell Biochem. 2011 Jun; 112(6):1563-71. PMID: 21344484; PMCID: PMC3329373.
    15. Azhdarinia A, Wilganowski N, Robinson H, Ghosh P, Kwon S, Lazard ZW, Davis AR, Olmsted-Davis E, Sevick-Muraca EM. Characterization of chemical, radiochemical and optical properties of a dual-labeled MMP-9 targeting peptide. Bioorg Med Chem. 2011 Jun 15; 19(12):3769-76. PMID: 21612930; PMCID: PMC3148023.
    16. Hsu CW, Olabisi RM, Olmsted-Davis EA, Davis AR, West JL. Cathepsin K-sensitive poly(ethylene glycol) hydrogels for degradation in response to bone resorption. J Biomed Mater Res A. 2011 Jul; 98(1):53-62. PMID: 21523904.
      View in: PubMed
    17. Liu SH, Smyth-Templeton N, Davis AR, Davis EA, Ballian N, Li M, Liu H, Fisher W, Brunicardi FC. Multiple treatment cycles of liposome-encapsulated adenoviral RIP-TK gene therapy effectively ablate human pancreatic cancer cells in SCID mice. Surgery. 2011 Apr; 149(4):484-95. PMID: 21295812; PMCID: PMC3072061.
    18. Olabisi RM, Lazard Z, Heggeness MH, Moran KM, Hipp JA, Dewan AK, Davis AR, West JL, Olmsted-Davis EA. An injectable method for noninvasive spine fusion. Spine J. 2011 Jun; 11(6):545-56. PMID: 21292563; PMCID: PMC3327508.
    19. Stephens EH, Saltarrelli JG, Baggett LS, Nandi I, Kuo JJ, Davis AR, Olmsted-Davis EA, Reardon MJ, Morrisett JD, Grande-Allen KJ. Differential proteoglycan and hyaluronan distribution in calcified aortic valves. Cardiovasc Pathol. 2011 Nov-Dec; 20(6):334-42. PMID: 21185747; PMCID: PMC3075347.
    20. Olabisi RM, Lazard ZW, Franco CL, Hall MA, Kwon SK, Sevick-Muraca EM, Hipp JA, Davis AR, Olmsted-Davis EA, West JL. Hydrogel microsphere encapsulation of a cell-based gene therapy system increases cell survival of injected cells, transgene expression, and bone volume in a model of heterotopic ossification. Tissue Eng Part A. 2010 Dec; 16(12):3727-36. PMID: 20673027; PMCID: PMC3120095.
    21. Dewan AK, Dewan RA, Calderon N, Fuentes A, Lazard Z, Davis AR, Heggeness M, Hipp JA, Olmsted-Davis EA. Assessing mechanical integrity of spinal fusion by in situ endochondral osteoinduction in the murine model. J Orthop Surg Res. 2010; 5:58. PMID: 20727195; PMCID: PMC2933711.
    22. Dilling CF, Wada AM, Lazard ZW, Salisbury EA, Gannon FH, Vadakkan TJ, Gao L, Hirschi K, Dickinson ME, Davis AR, Olmsted-Davis EA. Vessel formation is induced prior to the appearance of cartilage in BMP-2-mediated heterotopic ossification. J Bone Miner Res. 2010 May; 25(5):1147-56. PMID: 19839764; PMCID: PMC3153372.
    23. Salisbury E, Sonnet C, Heggeness M, Davis AR, Olmsted-Davis E. Heterotopic ossification has some nerve. Crit Rev Eukaryot Gene Expr. 2010; 20(4):313-24. PMID: 21395504; PMCID: PMC4535924.
    24. Shafer J, Davis AR, Gannon FH, Fouletier-Dilling CM, Lazard Z, Moran K, Gugala Z, Ozen M, Ittmann M, Heggeness MH, Olmsted-Davis E. Oxygen tension directs chondrogenic differentiation of myelo-monocytic progenitors during endochondral bone formation. Tissue Eng. 2007 Aug; 13(8):2011-9. PMID: 17518751.
      View in: PubMed
    25. Fouletier-Dilling CM, Gannon FH, Olmsted-Davis EA, Lazard Z, Heggeness MH, Shafer JA, Hipp JA, Davis AR. Efficient and rapid osteoinduction in an immune-competent host. Hum Gene Ther. 2007 Aug; 18(8):733-45. PMID: 17691858.
      View in: PubMed
    26. Gugala Z, Davis AR, Fouletier-Dilling CM, Gannon FH, Lindsey RW, Olmsted-Davis EA. Adenovirus BMP2-induced osteogenesis in combination with collagen carriers. Biomaterials. 2007 Oct; 28(30):4469-79. PMID: 17645942.
      View in: PubMed
    27. Bikram M, Fouletier-Dilling C, Hipp JA, Gannon F, Davis AR, Olmsted-Davis EA, West JL. Endochondral bone formation from hydrogel carriers loaded with BMP2-transduced cells. Ann Biomed Eng. 2007 May; 35(5):796-807. PMID: 17340196.
      View in: PubMed
    28. Olmsted-Davis E, Gannon FH, Ozen M, Ittmann MM, Gugala Z, Hipp JA, Moran KM, Fouletier-Dilling CM, Schumara-Martin S, Lindsey RW, Heggeness MH, Brenner MK, Davis AR. Hypoxic adipocytes pattern early heterotopic bone formation. Am J Pathol. 2007 Feb; 170(2):620-32. PMID: 17255330; PMCID: PMC1851874.
    29. Bosch P, Fouletier-Dilling C, Olmsted-Davis EA, Davis AR, Stice SL. Efficient adenoviral-mediated gene delivery into porcine mesenchymal stem cells. Mol Reprod Dev. 2006 Nov; 73(11):1393-403. PMID: 16897738.
      View in: PubMed
    30. Xue W, Wallin R, Olmsted-Davis EA, BorrĂ¡s T. Matrix GLA protein function in human trabecular meshwork cells: inhibition of BMP2-induced calcification process. Invest Ophthalmol Vis Sci. 2006 Mar; 47(3):997-1007. PMID: 16505034; PMCID: PMC1592516.
    31. Fouletier-Dilling CM, Bosch P, Davis AR, Shafer JA, Stice SL, Gugala Z, Gannon FH, Olmsted-Davis EA. Novel compound enables high-level adenovirus transduction in the absence of an adenovirus-specific receptor. Hum Gene Ther. 2005 Nov; 16(11):1287-97. PMID: 16259562.
      View in: PubMed
    32. Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A. Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr; 229(4):826-34. PMID: 15042706.
      View in: PubMed
    33. Olmsted-Davis EA, Gugala Z, Camargo F, Gannon FH, Jackson K, Kienstra KA, Shine HD, Lindsey RW, Hirschi KK, Goodell MA, Brenner MK, Davis AR. Primitive adult hematopoietic stem cells can function as osteoblast precursors. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15877-82. PMID: 14673088; PMCID: PMC307661.
    34. Sili U, Huls MH, Davis AR, Gottschalk S, Brenner MK, Heslop HE, Rooney CM. Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy. J Immunother. 2003 May-Jun; 26(3):241-56. PMID: 12806278.
      View in: PubMed
    35. Gottschalk S, Edwards OL, Sili U, Huls MH, Goltsova T, Davis AR, Heslop HE, Rooney CM. Generating CTLs against the subdominant Epstein-Barr virus LMP1 antigen for the adoptive immunotherapy of EBV-associated malignancies. Blood. 2003 Mar 1; 101(5):1905-12. PMID: 12411306.
      View in: PubMed
    36. Olmsted-Davis EA, Gugala Z, Gannon FH, Yotnda P, McAlhany RE, Lindsey RW, Davis AR. Use of a chimeric adenovirus vector enhances BMP2 production and bone formation. Hum Gene Ther. 2002 Jul 20; 13(11):1337-47. PMID: 12162816.
      View in: PubMed
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