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DAVID SHEIKH-HAMAD

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressONE BAYLOR PLAZA
HOUSTON TX 77030
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    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Glaser J, Lemery J, Rajagopalan B, Diaz HF, García-Trabanino R, Taduri G, Madero M, Amarasinghe M, Abraham G, Anutrakulchai S, Jha V, Stenvinkel P, Roncal-Jimenez C, Lanaspa MA, Correa-Rotter R, Sheikh-Hamad D, Burdmann EA, Andres-Hernando A, Milagres T, Weiss I, Kanbay M, Wesseling C, Sánchez-Lozada LG, Johnson RJ. Climate Change and the Emergent Epidemic of CKD from Heat Stress in Rural Communities: The Case for Heat Stress Nephropathy. Clin J Am Soc Nephrol. 2016 Aug 8; 11(8):1472-83. PMID: 27151892; PMCID: PMC4974898 [Available on 08/08/17].
    2. Lin L, Lee JH, Buras ED, Yu K, Wang R, Smith CW, Wu H, Sheikh-Hamad D, Sun Y. Ghrelin receptor regulates adipose tissue inflammation in aging. Aging (Albany NY). 2016 Jan; 8(1):178-91. PMID: 26837433; PMCID: PMC4761721.
    3. Huang L, Zhang L, Ju H, Li Q, Pan JS, Al-Lawati Z, Sheikh-Hamad D. Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury. Sci Rep. 2015; 5:18117. PMID: 26640170.
      View in: PubMed
    4. Pan JS, Sheikh-Hamad D. Remote Ischemic Preconditioning and Postoperative Renal Dysfunction--Reply. JAMA. 2015 Oct 13; 314(14):1520. PMID: 26462007.
      View in: PubMed
    5. Huang L, Lou Y, Ju H, Zhang L, Pan JS, Ross A, Sun Y, Truong LD, Sheikh-Hamad D. Severe Nephrotoxic Nephritis following Conditional and Kidney-Specific Knockdown of Stanniocalcin-1. PLoS One. 2015; 10(9):e0138440. PMID: 26393521.
      View in: PubMed
    6. Pan JS, Sheikh-Hamad D. Remote ischemic preconditioning for kidney protection. JAMA. 2015 Jun 2; 313(21):2124-5. PMID: 26024384.
      View in: PubMed
    7. Scherzer P, Gal-Moscovici A, Sheikh-Hamad D, Popovtzer MM. Sodium-pump gene-expression, protein abundance and enzyme activity in isolated nephron segments of the aging rat kidney. Physiol Rep. 2015 Jun; 3(6). PMID: 26056060.
      View in: PubMed
    8. Lin L, Lee JH, Bongmba OY, Ma X, Zhu X, Sheikh-Hamad D, Sun Y. The suppression of ghrelin signaling mitigates age?associated thermogenic impairment. Aging (Albany NY). 2014 Dec; 6(12):1019-32. PMID: 25543537; PMCID: PMC4298363.
    9. Pan JS, Huang L, Belousova T, Lu L, Yang Y, Reddel R, Chang A, Ju H, DiMattia G, Tong Q, Sheikh-Hamad D. Stanniocalcin-1 inhibits renal ischemia/reperfusion injury via an AMP-activated protein kinase-dependent pathway. J Am Soc Nephrol. 2015 Feb; 26(2):364-78. PMID: 25012175; PMCID: PMC4310644.
    10. Huang L, Belousova T, Pan JS, Du J, Ju H, Lu L, Zhang P, Truong LD, Nuotio-Antar A, Sheikh-Hamad D. AKI after conditional and kidney-specific knockdown of stanniocalcin-1. J Am Soc Nephrol. 2014 Oct; 25(10):2303-15. PMID: 24700878; PMCID: PMC4178431.
    11. Ma X, Lin L, Yue J, Pradhan G, Qin G, Minze LJ, Wu H, Sheikh-Hamad D, Smith CW, Sun Y. Ghrelin receptor regulates HFCS-induced adipose inflammation and insulin resistance. Nutr Diabetes. 2013; 3:e99. PMID: 24366371; PMCID: PMC3877431.
    12. Sheikh-Hamad D. From TOR and SMAD, why HIF-1? can be bad. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F170-1. PMID: 24049143; PMCID: PMC3961556.
    13. Huang L, Belousova T, Chen M, DiMattia G, Liu D, Sheikh-Hamad D. Overexpression of stanniocalcin-1 inhibits reactive oxygen species and renal ischemia/reperfusion injury in mice. Kidney Int. 2012 Oct; 82(8):867-77. PMID: 22695329; PMCID: PMC3443530.
    14. Liu D, Huang L, Wang Y, Wang W, Wehrens XH, Belousova T, Abdelrahim M, DiMattia G, Sheikh-Hamad D. Human stanniocalcin-1 suppresses angiotensin II-induced superoxide generation in cardiomyocytes through UCP3-mediated anti-oxidant pathway. PLoS One. 2012; 7(5):e36994. PMID: 22693564; PMCID: PMC3365029.
    15. Kagan A, Sheikh-Hamad D. Contrast-induced kidney injury: focus on modifiable risk factors and prophylactic strategies. Clin Cardiol. 2010 Feb; 33(2):62-6. PMID: 20186983.
      View in: PubMed
    16. Colon J, Basha MR, Madero-Visbal R, Konduri S, Baker CH, Herrera LJ, Safe S, Sheikh-Hamad D, Abudayyeh A, Alvarado B, Abdelrahim M. Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice. Invest New Drugs. 2011 Feb; 29(1):41-51. PMID: 19851711.
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    17. Sheikh-Hamad D. Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. Am J Physiol Renal Physiol. 2010 Feb; 298(2):F248-54. PMID: 19656913; PMCID: PMC3774476.
    18. Wang Y, Huang L, Abdelrahim M, Cai Q, Truong A, Bick R, Poindexter B, Sheikh-Hamad D. Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2. J Leukoc Biol. 2009 Oct; 86(4):981-8. PMID: 19602668; PMCID: PMC2752019.
    19. Huang L, Garcia G, Lou Y, Zhou Q, Truong LD, DiMattia G, Lan XR, Lan HY, Wang Y, Sheikh-Hamad D. Anti-inflammatory and renal protective actions of stanniocalcin-1 in a model of anti-glomerular basement membrane glomerulonephritis. Am J Pathol. 2009 Apr; 174(4):1368-78. PMID: 19246645; PMCID: PMC2671368.
    20. Stephen MJ, Poindexter BJ, Moolman JA, Sheikh-Hamad D, Bick RJ. Do binucleate cardiomyocytes have a role in myocardial repair? Insights using isolated rodent myocytes and cell culture. Open Cardiovasc Med J. 2009; 3:1-7. PMID: 19430572; PMCID: PMC2678822.
    21. Sheikh-Hamad D. Cisplatin-induced cytoxicity: is the nucleus relevant? Am J Physiol Renal Physiol. 2008 Jul; 295(1):F42-3. PMID: 18480173.
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    22. Chen C, Jamaluddin MS, Yan S, Sheikh-Hamad D, Yao Q. Human stanniocalcin-1 blocks TNF-alpha-induced monolayer permeability in human coronary artery endothelial cells. Arterioscler Thromb Vasc Biol. 2008 May; 28(5):906-12. PMID: 18309109; PMCID: PMC2731718.
    23. Sheikh-Hamad D, Paiuk E, Wright AJ, Kleinmann C, Khosla U, Shandera WX. Care for immigrants with end-stage renal disease in Houston: a comparison of two practices. Tex Med. 2007 Apr; 103(4):54-8, 53. PMID: 17494250.
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    24. Abdelrahim M, Baker CH, Abbruzzese JL, Sheikh-Hamad D, Liu S, Cho SD, Yoon K, Safe S. Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. Cancer Res. 2007 Apr 1; 67(7):3286-94. PMID: 17409437.
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    25. Chakraborty A, Brooks H, Zhang P, Smith W, McReynolds MR, Hoying JB, Bick R, Truong L, Poindexter B, Lan H, Elbjeirami W, Sheikh-Hamad D. Stanniocalcin-1 regulates endothelial gene expression and modulates transendothelial migration of leukocytes. Am J Physiol Renal Physiol. 2007 Feb; 292(2):F895-904. PMID: 17032941.
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    26. Padda R, Wamsley-Davis A, Gustin MC, Ross R, Yu C, Sheikh-Hamad D. MEKK3-mediated signaling to p38 kinase and TonE in hypertonically stressed kidney cells. Am J Physiol Renal Physiol. 2006 Oct; 291(4):F874-81. PMID: 16684924.
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    27. Sule N, Yakupoglu U, Shen SS, Krishnan B, Yang G, Lerner S, Sheikh-Hamad D, Truong LD. Calcium oxalate deposition in renal cell carcinoma associated with acquired cystic kidney disease: a comprehensive study. Am J Surg Pathol. 2005 Apr; 29(4):443-51. PMID: 15767796.
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    28. Hou CC, Wang W, Huang XR, Fu P, Chen TH, Sheikh-Hamad D, Lan HY. Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney. Am J Pathol. 2005 Mar; 166(3):761-71. PMID: 15743788; PMCID: PMC1602350.
    29. Sheikh-Hamad D, Gustin MC. MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals. Am J Physiol Renal Physiol. 2004 Dec; 287(6):F1102-10. PMID: 15522988.
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    30. Truong LD, Yakupoglu U, Feig D, Hicks J, Cartwight J, Sheikh-Hamad D, Suki WN. Calcium oxalate deposition in renal allografts: morphologic spectrum and clinical implications. Am J Transplant. 2004 Aug; 4(8):1338-44. PMID: 15268737.
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    31. Wamsley-Davis A, Padda R, Truong LD, Tsao CC, Zhang P, Sheikh-Hamad D. AT1A-mediated activation of kidney JNK1 and SMAD2 in obstructive uropathy: preservation of kidney tissue mass using candesartan. Am J Physiol Renal Physiol. 2004 Sep; 287(3):F474-80. PMID: 15126250.
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    32. Kanellis J, Bick R, Garcia G, Truong L, Tsao CC, Etemadmoghadam D, Poindexter B, Feng L, Johnson RJ, Sheikh-Hamad D. Stanniocalcin-1, an inhibitor of macrophage chemotaxis and chemokinesis. Am J Physiol Renal Physiol. 2004 Feb; 286(2):F356-62. PMID: 14570698.
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    33. Sheikh-Hamad D, Cacini W, Buckley AR, Isaac J, Truong LD, Tsao CC, Kishore BK. Cellular and molecular studies on cisplatin-induced apoptotic cell death in rat kidney. Arch Toxicol. 2004 Mar; 78(3):147-55. PMID: 14551673.
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    34. Kanellis J, Watanabe S, Li JH, Kang DH, Li P, Nakagawa T, Wamsley A, Sheikh-Hamad D, Lan HY, Feng L, Johnson RJ. Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension. 2003 Jun; 41(6):1287-93. PMID: 12743010.
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    35. Mai HL, Sheikh-Hamad D, Herrera GA, Gu X, Truong LD. Immunoglobulin heavy chain can be amyloidogenic: morphologic characterization including immunoelectron microscopy. Am J Surg Pathol. 2003 Apr; 27(4):541-5. PMID: 12657941.
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    36. Sheikh-Hamad D, Bick R, Wu GY, Christensen BM, Razeghi P, Poindexter B, Taegtmeyer H, Wamsley A, Padda R, Entman M, Nielsen S, Youker K. Stanniocalcin-1 is a naturally occurring L-channel inhibitor in cardiomyocytes: relevance to human heart failure. Am J Physiol Heart Circ Physiol. 2003 Jul; 285(1):H442-8. PMID: 12663264.
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    37. Sheikh-Hamad D, Nadkarni V, Choi YJ, Truong LD, Wideman C, Hodjati R, Gabbay KH. Cyclosporine A inhibits the adaptive responses to hypertonicity: a potential mechanism of nephrotoxicity. J Am Soc Nephrol. 2001 Dec; 12(12):2732-41. PMID: 11729242.
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    38. Truong LD, Choi YJ, Tsao CC, Ayala G, Sheikh-Hamad D, Nassar G, Suki WN. Renal cell apoptosis in chronic obstructive uropathy: the roles of caspases. Kidney Int. 2001 Sep; 60(3):924-34. PMID: 11532087.
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    39. Choi YJ, Mendoza L, Rha SJ, Sheikh-Hamad D, Baranowska-Daca E, Nguyen V, Smith CW, Nassar G, Suki WN, Truong LD. Role of p53-dependent activation of caspases in chronic obstructive uropathy: evidence from p53 null mutant mice. J Am Soc Nephrol. 2001 May; 12(5):983-92. PMID: 11316857.
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    40. Choi YJ, Baranowska-Daca E, Nguyen V, Koji T, Ballantyne CM, Sheikh-Hamad D, Suki WN, Truong LD. Mechanism of chronic obstructive uropathy: increased expression of apoptosis-promoting molecules. Kidney Int. 2000 Oct; 58(4):1481-91. PMID: 11012883.
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    41. Sheikh-Hamad D, Youker K, Truong LD, Nielsen S, Entman ML. Osmotically relevant membrane signaling complex: association between HB-EGF, beta(1)-integrin, and CD9 in mTAL. Am J Physiol Cell Physiol. 2000 Jul; 279(1):C136-46. PMID: 10898725.
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    42. Sheikh-Hamad D, Rouse D, Yang Y. Regulation of stanniocalcin in MDCK cells by hypertonicity and extracellular calcium. Am J Physiol Renal Physiol. 2000 Mar; 278(3):F417-24. PMID: 10710546.
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    43. Nadkarni V, Gabbay KH, Bohren KM, Sheikh-Hamad D. Osmotic response element enhancer activity. Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase. J Biol Chem. 1999 Jul 16; 274(29):20185-90. PMID: 10400634.
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    44. Truong LD, Sheikh-Hamad D, Chakraborty S, Suki WN. Cell apoptosis and proliferation in obstructive uropathy. Semin Nephrol. 1998 Nov; 18(6):641-51. PMID: 9819155.
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    45. Sheikh-Hamad D, Ayus CJ. Antidiuretic hormone and renal clearance of uric acid. Am J Kidney Dis. 1998 Oct; 32(4):692-3; discussion 694-7. PMID: 9774136.
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    46. Ayus JC, Sheikh-Hamad D. Dialysis therapy. N Engl J Med. 1998 Oct 1; 339(14):1003-4; author reply 1005. PMID: 9766986.
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    47. Sheikh-Hamad D, Ayus JC. The patient with a clotted PTFE graft developing fever. Nephrol Dial Transplant. 1998 Sep; 13(9):2392-3. PMID: 9761534.
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    48. Christensen BM, Marples D, Jensen UB, Frokiaer J, Sheikh-Hamad D, Knepper M, Nielsen S. Acute effects of vasopressin V2-receptor antagonist on kidney AQP2 expression and subcellular distribution. Am J Physiol. 1998 Aug; 275(2 Pt 2):F285-97. PMID: 9691020.
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    49. Ayus JC, Sheikh-Hamad D. Silent infection in clotted hemodialysis access grafts. J Am Soc Nephrol. 1998 Jul; 9(7):1314-7. PMID: 9644644.
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    50. Sheikh-Hamad D, Di Mari J, Suki WN, Safirstein R, Watts BA, Rouse D. p38 kinase activity is essential for osmotic induction of mRNAs for HSP70 and transporter for organic solute betaine in Madin-Darby canine kidney cells. J Biol Chem. 1998 Jan 16; 273(3):1832-7. PMID: 9430735.
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    51. Faustinella F, Uzoh C, Sheikh-Hamad D, Truong LD, Olivero JJ. Glomerulomegaly and proteinuria in a patient with idiopathic pulmonary hypertension. J Am Soc Nephrol. 1997 Dec; 8(12):1966-70. PMID: 9402101.
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    52. Sheikh-Hamad D, Timmins K, Jalali Z. Cisplatin-induced renal toxicity: possible reversal by N-acetylcysteine treatment. J Am Soc Nephrol. 1997 Oct; 8(10):1640-4. PMID: 9335396.
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    53. Sheikh-Hamad D, Suki WN, Zhao W. Hypertonic induction of the cell adhesion molecule beta 1-integrin in MDCK cells. Am J Physiol. 1997 Sep; 273(3 Pt 1):C902-8. PMID: 9316411.
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    54. Sheikh-Hamad D, Ferraris JD, Dragolovich J, Preuss HG, Burg MB, García-Pérez A. CD9 antigen mRNA is induced by hypertonicity in two renal epithelial cell lines. Am J Physiol. 1996 Jan; 270(1 Pt 1):C253-8. PMID: 8772451.
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    55. Sheikh-Hamad D, García-Pérez A, Ferraris JD, Peters EM, Burg MB. Induction of gene expression by heat shock versus osmotic stress. Am J Physiol. 1994 Jul; 267(1 Pt 2):F28-34. PMID: 8048561.
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    56. Sheikh-Hamad D, Wang YP, Jo OD, Yanagawa N. Dopamine antagonizes the actions of angiotensin II in renal brush-border membrane. Am J Physiol. 1993 Apr; 264(4 Pt 2):F737-43. PMID: 8386474.
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    57. Morduchowicz GA, Sheikh-Hamad D, Dwyer BE, Stern N, Jo OD, Yanagawa N. Angiotensin II directly increases rabbit renal brush-border membrane sodium transport: presence of local signal transduction system. J Membr Biol. 1991 May; 122(1):43-53. PMID: 1652030.
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    58. Morduchowicz GA, Sheikh-Hamad D, Jo OD, Nord EP, Lee DB, Yanagawa N. Increased Na+/H+ antiport activity in the renal brush border membrane of SHR. Kidney Int. 1989 Oct; 36(4):576-81. PMID: 2554051.
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    59. Bassan MM, Sheikh-Hamad D. Prevention of lidocaine-infusion phlebitis by heparin and hydrocortisone. Chest. 1983 Oct; 84(4):439-41. PMID: 6617280.
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