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NORMAN LESLIE SUSSMAN

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
Address6620 Main Stree, Suite 1425
Houston TX 77030
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    Dr. Norman L. Sussman is leading an effort to improve medical resources in rural and underserved communities in Texas using a videoconference outreach model. He is also continuing to refine methods of assessing risk in patient with acute liver failure.

    Dr. Sussman is an active member of the Baylor - St. Luke’s Liver Center. He is Board Certified in Internal Medicine, Gastroenterology, and Transplant Hepatology. His clinical interests cover all aspects of liver disease, and his research interests include assessment and management of acute liver failure, artificial liver support, new agents to treat viral hepatitis, and complications of advanced cirrhosis.

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    • Assessment and management of acute liver failure
    • Artificial liver support
    • Complications of advanced cirrhosis
    • New agents to treat viral hepatitis


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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Thornton K, Deming P, Manch RA, Moore A, Kohli A, Gish R, Sussman NL, Khaderi S, Scott J, Mera J, Box T, Qualls C, Sedillo M, Arora S. Is response guided therapy dead? Low cure rates in patients with detectable hepatitis C virus at week 4 of treatment. Hepatol Int. 2016 Jul; 10(4):624-31. PMID: 27098355.
      View in: PubMed
    2. Carrion AF, Khaderi SA, Sussman NL. Model for end-stage liver disease limbo, model for end-stage liver disease purgatory, and the dilemma of treating hepatitis C in patients awaiting liver transplantation. Liver Transpl. 2016 Mar; 22(3):279-80. PMID: 26663608.
      View in: PubMed
    3. Sussman NL. Treatment of Overt Hepatic Encephalopathy. Clin Liver Dis. 2015 Aug; 19(3):551-63. PMID: 26195208.
      View in: PubMed
    4. Khaderi SA, Sussman NL. Screening for malignancy in primary sclerosing cholangitis (PSC). Curr Gastroenterol Rep. 2015 Apr; 17(4):17. PMID: 25786901.
      View in: PubMed
    5. Sussman NL, Kelly JH. Artificial liver. Clin Gastroenterol Hepatol. 2014 Sep; 12(9):1439-42. PMID: 24909908.
      View in: PubMed
    6. Khaderi S, Khan R, Safdar Z, Stribling R, Vierling JM, Goss JA, Sussman NL. Long-term follow-up of portopulmonary hypertension patients after liver transplantation. Liver Transpl. 2014 Jun; 20(6):724-7. PMID: 24648168.
      View in: PubMed
    7. Sussman NL, Remien CH, Kanwal F. The end of hepatitis C. Clin Gastroenterol Hepatol. 2014 Apr; 12(4):533-6. PMID: 24480676.
      View in: PubMed
    8. Remien CH, Sussman NL, Adler FR. Mathematical modelling of chronic acetaminophen metabolism and liver injury. Math Med Biol. 2014 Sep; 31(3):302-17. PMID: 23788256.
      View in: PubMed
    9. Safdar Z, Bartolome S, Sussman N. Portopulmonary hypertension: an update. Liver Transpl. 2012 Aug; 18(8):881-91. PMID: 22674534.
      View in: PubMed
    10. Remien CH, Adler FR, Waddoups L, Box TD, Sussman NL. Mathematical modeling of liver injury and dysfunction after acetaminophen overdose: early discrimination between survival and death. Hepatology. 2012 Aug; 56(2):727-34. PMID: 22331703.
      View in: PubMed
    11. Sussman NL, Kochar R, Fallon MB. Pulmonary complications in cirrhosis. Curr Opin Organ Transplant. 2011 Jun; 16(3):281-8. PMID: 21543981.
      View in: PubMed
    12. Salek J, Byrne J, Box T, Longo N, Sussman N. Recurrent liver failure in a 25-year-old female. Liver Transpl. 2010 Sep; 16(9):1049-53. PMID: 20818742.
      View in: PubMed
    13. Sussman NL, McGuire BM, Kelly JH. Hepatic assist devices: will they ever be successful? Curr Gastroenterol Rep. 2009 Feb; 11(1):64-8. PMID: 19166661.
      View in: PubMed
    14. Sussman NL, Lee PL, Dries AM, Schwartz MR, Barton JC. Multi-organ iron overload in an African-American man with ALAS2 R452S and SLC40A1 R561G. Acta Haematol. 2008; 120(3):168-73. PMID: 19066423.
      View in: PubMed
    15. Agha A, Sussman N. Acute hepatic dysfunction with abdominal pain and ascites. MedGenMed. 2007; 9(2):31. PMID: 17955086; PMCID: PMC1994833.
    16. Sussman N, Kaza V, Barshes N, Stribling R, Goss J, O'Mahony C, Zhang E, Vierling J, Frost A. Successful liver transplantation following medical management of portopulmonary hypertension: a single-center series. Am J Transplant. 2006 Sep; 6(9):2177-82. PMID: 16796721.
      View in: PubMed
    17. Stribling R, Sussman N, Vierling JM. Treatment of hepatitis C infection. Gastroenterol Clin North Am. 2006 Jun; 35(2):463-86. PMID: 16880075.
      View in: PubMed
    18. Woofter A, Sussman N. Jaundice in a traveler returning from India. MedGenMed. 2006; 8(1):48. PMID: 16915178; PMCID: PMC1681962.
    19. Clark RD, Wolohan PR, Hodgkin EE, Kelly JH, Sussman NL. Modelling in vitro hepatotoxicity using molecular interaction fields and SIMCA. J Mol Graph Model. 2004 Jul; 22(6):487-97. PMID: 15182808.
      View in: PubMed
    20. Kelly JH, Sussman NL. A fluorescent cell-based assay for cytochrome P-450 isozyme 1A2 induction and inhibition. J Biomol Screen. 2000 Aug; 5(4):249-54. PMID: 10992045.
      View in: PubMed
    21. Sussman NL, Kelly JH. Extracorporeal liver support: cell-based therapy for the failing liver. Am J Kidney Dis. 1997 Nov; 30(5 Suppl 4):S66-71. PMID: 9372981.
      View in: PubMed
    22. Ellis AJ, Hughes RD, Wendon JA, Dunne J, Langley PG, Kelly JH, Gislason GT, Sussman NL, Williams R. Pilot-controlled trial of the extracorporeal liver assist device in acute liver failure. Hepatology. 1996 Dec; 24(6):1446-51. PMID: 8938179.
      View in: PubMed
    23. Sussman NL, Kelly JH. Artificial liver support. Clin Invest Med. 1996 Oct; 19(5):393-9. PMID: 8889280.
      View in: PubMed
    24. Sussman NL, Lake JR. Treatment of hepatic failure--1996: current concepts and progress toward liver dialysis. Am J Kidney Dis. 1996 May; 27(5):605-21. PMID: 8629619.
      View in: PubMed
    25. Lake JR, Sussman NL. Determining prognosis in patients with fulminant hepatic failure: when you absolutely, positively have to know the answer. Hepatology. 1995 Mar; 21(3):879-82. PMID: 7875687.
      View in: PubMed
    26. Sussman NL, Finegold MJ, Barish JP, Kelly JH. A case of syncytial giant-cell hepatitis treated with an extracorporeal liver assist device. Am J Gastroenterol. 1994 Jul; 89(7):1077-82. PMID: 7517100.
      View in: PubMed
    27. Sussman NL, Gislason GT, Kelly JH. Extracorporeal liver support. Application to fulminant hepatic failure. J Clin Gastroenterol. 1994 Jun; 18(4):320-4. PMID: 8071519.
      View in: PubMed
    28. Sussman NL, Gislason GT, Conlin CA, Kelly JH. The Hepatix extracorporeal liver assist device: initial clinical experience. Artif Organs. 1994 May; 18(5):390-6. PMID: 8037614.
      View in: PubMed
    29. Gislason GT, Lobdell DD, Kelly JH, Sussman NL. A treatment system for implementing an extracorporeal liver assist device. Artif Organs. 1994 May; 18(5):385-9. PMID: 8037613.
      View in: PubMed
    30. Kelly JH, Sussman NL. The hepatix extracorporeal liver assist device in the treatment of fulminant hepatic failure. ASAIO J. 1994 Jan-Mar; 40(1):83-5. PMID: 7514459.
      View in: PubMed
    31. Wood RP, Katz SM, Ozaki CF, Monsour HP, Gislason GT, Kelly JH, Sussman NL. Extracorporeal liver assist device (ELAD): a preliminary report. Transplant Proc. 1993 Aug; 25(4 Suppl 3):53-4. PMID: 8351720.
      View in: PubMed
    32. Sussman NL, Kelly JH. Artificial liver: a forthcoming attraction. Hepatology. 1993 Jun; 17(6):1163-4. PMID: 8514267.
      View in: PubMed
    33. Sussman NL, Kelly JH. Improved liver function following treatment with an extracorporeal liver assist device. Artif Organs. 1993 Jan; 17(1):27-30. PMID: 8422230.
      View in: PubMed
    34. Sussman NL, Kelly JH. Extracorporeal liver assist in the treatment of fulminant hepatic failure. Blood Purif. 1993; 11(3):170-4. PMID: 8280439.
      View in: PubMed
    35. Sussman NL, Kelly JH. Liver assist devices (LADs) will not be used to treat fulminant hepatic failure (FHF), but its consequences, namely hepatic encephalopathy (HE) Artif Organs. 1993 Jan; 17(1):43-5. PMID: 8422234.
      View in: PubMed
    36. Kelly JH, Koussayer T, He D, Chong MG, Shang TA, Whisennand HH, Sussman NL. Assessment of an extracorporeal liver assist device in anhepatic dogs. Artif Organs. 1992 Aug; 16(4):418-22. PMID: 10078286.
      View in: PubMed
    37. Sussman NL, Chong MG, Koussayer T, He DE, Shang TA, Whisennand HH, Kelly JH. Reversal of fulminant hepatic failure using an extracorporeal liver assist device. Hepatology. 1992 Jul; 16(1):60-5. PMID: 1618484.
      View in: PubMed
    38. Kelly JH, Koussayer T, He DE, Chong MG, Shang TA, Whisennand HH, Sussman NL. An improved model of acetaminophen-induced fulminant hepatic failure in dogs. Hepatology. 1992 Feb; 15(2):329-35. PMID: 1735538.
      View in: PubMed
    39. Sussman NL, Eliakim R, Rubin D, Perlmutter DH, DeSchryver-Kecskemeti K, Alpers DH. Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes. Am J Physiol. 1989 Jul; 257(1 Pt 1):G14-23. PMID: 2546440.
      View in: PubMed
    40. Go MF, Schonfeld G, Pfleger B, Cole TG, Sussman NL, Alpers DH. Regulation of intestinal and hepatic apoprotein synthesis after chronic fat and cholesterol feeding. J Clin Invest. 1988 May; 81(5):1615-20. PMID: 3130399; PMCID: PMC442597.
    41. Seetharam S, Sussman NL, Komoda T, Alpers DH. The mechanism of elevated alkaline phosphatase activity after bile duct ligation in the rat. Hepatology. 1986 May-Jun; 6(3):374-80. PMID: 3710426.
      View in: PubMed
    42. Sussman NL, Seetharam S, Blaufuss MC, Alpers DH. Translation of rat intestinal RNA yields two alkaline phosphatases. Biochem J. 1986 Mar 15; 234(3):563-8. PMID: 2424431; PMCID: PMC1146608.
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