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GEORGE TAFFET

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address6501 Fannin St
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Integrative Physiology
    DivisionMolecular Physiology & Biophysics

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentHuffington Center on Aging
    DivisionHuffington Ctr on Aging


    Collapse Research 
    Collapse research activities and funding
    R42HL144342     (CHIRIVA-INTERNATI, MAURIZIO)Sep 1, 2018 - Aug 31, 2021
    NIH
    Development and non-clinical GLP testing of a new anti-arteriosclerosis gene therapy delivered by engineered adeno-associated viral vectors.
    Role: Co-Principal Investigator
    R01AG017899     (TAFFET, GEORGE E)Sep 30, 2001 - Jul 31, 2007
    NIH
    Pathogenesis of Age-Related Diastolic Dysfunction
    Role: Principal Investigator
    R03AG015568     (TAFFET, GEORGE E)May 1, 1998 - Apr 30, 2000
    NIH
    ARTERIAL STIFFENING IN THE AGING MOUSE
    Role: Principal Investigator
    R01AG013251     (TAFFET, GEORGE E)Feb 5, 1995 - Dec 31, 1997
    NIH
    LIPID MODIFICATION OF THE SENESCENT HEART
    Role: Principal Investigator
    K08AG000428     (TAFFET, GEORGE E)Dec 1, 1988 - Dec 30, 1994
    NIH
    MODULATION OF RELAXATION IN THE SENESCENT HEART
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Siddiqi TJ, Usman MS, Siddiqui A, Salman A, Talbot N, Khan LA, Shabbir A, Hall ME, Taffet GE, Taffet GE. Association of low diastolic blood pressure with cardiovascular outcomes and all-cause mortality: A meta-analysis. Curr Probl Cardiol. 2024 Jan; 49(1 Pt C):102131. PMID: 37866417.
      Citations: 1     Fields:    Translation:Humans
    2. Al Rifai M, Taffet GE, Matsushita K, Virani SS, De Lemos J, Khera A, Berry J, Ndumele C, Aguilar D, Sun C, Hoogeveen RC, Selvin E, Ballantyne CM, Nambi V. Age-Related Differences in the Contribution of Systolic Blood Pressure and Biomarkers to Cardiovascular Disease Risk Prediction: The Atherosclerosis Risk in Communities (ARIC) Study. Am J Cardiol. 2023 10 01; 204:295-301. PMID: 37567021; PMCID: PMC10528351.
      Citations:    Fields:    Translation:Humans
    3. Forman DE, Kuchel GA, Newman JC, Kirkland JL, Volpi E, Taffet GE, Barzilai N, Pandey A, Kitzman DW, Libby P, Ferrucci L. Impact of Geroscience on Therapeutic Strategies for Older Adults With Cardiovascular Disease: JACC Scientific Statement. J Am Coll Cardiol. 2023 08 15; 82(7):631-647. PMID: 37389519; PMCID: PMC10414756.
      Citations:    Fields:    Translation:Humans
    4. Marshall AG, Neikirk K, Vue Z, Beasley HK, Garza-Lopez E, Vang L, Barongan T, Evans Z, Crabtree A, Spencer E, Anudokem J, Parker R, Davis J, Stephens D, Damo S, Pham TT, Gomez JA, Exil V, Dai DF, Murray SA, Entman ML, Taffet GE, Hinton AO, Reddy AK. Cardiovascular hemodynamics in mice with tumor necrosis factor receptor-associated factor 2 mediated cytoprotection in the heart. Front Cardiovasc Med. 2023; 10:1064640. PMID: 37229235; PMCID: PMC10203617.
      Citations:    
    5. Thomas C, Ellison H, Taffet GE. Deprescribing statins, considerations for informed decision making. J Am Geriatr Soc. 2023 08; 71(8):2685-2689. PMID: 37082816.
      Citations:    Fields:    Translation:Humans
    6. Kumar P, Liu C, Suliburk J, Hsu JW, Muthupillai R, Jahoor F, Minard CG, Taffet GE, Sekhar RV. Supplementing Glycine and N-Acetylcysteine (GlyNAC) in Older Adults Improves Glutathione Deficiency, Oxidative Stress, Mitochondrial Dysfunction, Inflammation, Physical Function, and Aging Hallmarks: A Randomized Clinical Trial. J Gerontol A Biol Sci Med Sci. 2023 01 26; 78(1):75-89. PMID: 35975308; PMCID: PMC9879756.
      Citations:    
    7. Angelini A, Ortiz-Urbina J, Trial J, Reddy AK, Malovannaya A, Jain A, Entman ML, Taffet GE, Cieslik KA. Sex-specific phenotypes in the aging mouse heart and consequences for chronic fibrosis. Am J Physiol Heart Circ Physiol. 2022 08 01; 323(2):H285-H300. PMID: 35714177; PMCID: PMC9273262.
      Citations:    Fields:    Translation:Animals
    8. Jia X, Sun C, Nambi V, Virani SS, Taffet G, Boerwinkle E, Bressler J, Ndumele C, Windham BG, de Lemos JA, Matsushita K, McEvoy JW, Hoogeveen RC, Selvin E, Ballantyne CM. Midlife determinants of healthy cardiovascular aging: The Atherosclerosis Risk in Communities (ARIC) study. Atherosclerosis. 2022 06; 350:82-89. PMID: 35550933; PMCID: PMC9627572.
      Citations:    Fields:    Translation:Humans
    9. Perez JET, Ortiz-Urbina J, Heredia CP, Pham TT, Madala S, Hartley CJ, Entman ML, Taffet GE, Reddy AK. Author Correction: Aortic acceleration as a noninvasive index of left ventricular contractility in the mouse. Sci Rep. 2021 Dec 03; 11(1):23743. PMID: 34862472; PMCID: PMC8642534.
      Citations:    Fields:    
    10. Pandey A, Shah SJ, Butler J, Kellogg DL, Lewis GD, Forman DE, Mentz RJ, Borlaug BA, Simon MA, Chirinos JA, Fielding RA, Volpi E, Molina AJA, Haykowsky MJ, Sam F, Goodpaster BH, Bertoni AG, Justice JN, White JP, Ding J, Hummel SL, LeBrasseur NK, Taffet GE, Pipinos II, Kitzman D. Exercise Intolerance in Older Adults With?Heart?Failure With Preserved Ejection?Fraction: JACC State-of-the-Art Review. J Am Coll Cardiol. 2021 09 14; 78(11):1166-1187. PMID: 34503685; PMCID: PMC8525886.
      Citations: 9     Fields:    Translation:HumansAnimals
    11. Scott L, Fender AC, Saljic A, Li L, Chen X, Wang X, Linz D, Lang J, Hohl M, Twomey D, Pham TT, Diaz-Lankenau R, Chelu MG, Kamler M, Entman ML, Taffet GE, Sanders P, Dobrev D, Li N. NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias. Cardiovasc Res. 2021 06 16; 117(7):1746-1759. PMID: 33523143; PMCID: PMC8208743.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    12. Maclullich AMJ, Anand A, Brookes C, Cassarino M, O'connor M, Ryan D, Saller T, Arora RC, Chang Y, Agarwal K, Taffet G, Quinn T, Shenkin SD, Galvin R, Tieges Z. Diagnostic accuracy of the 4AT for delirium detection in older adults: systematic review and meta-analysis. Age Ageing. 2021 05 05; 50(3):733-743. PMID: 33951145; PMCID: PMC8099016.
      Citations: 17     Fields:    Translation:HumansPHPublic Health
    13. Marian AJ, Asatryan B, Bolli R, Cheedipudi SM, Dhalla NS, Finkel T, Frangogiannis NG, Gurha P, Belmonte JCI, Hare JM, Hong K, Kirshenbaum LA, Lee RT, Leesar MA, Libby P, Madonna R, Nagueh SF, Roberts R, Rosenzweig A, Rouhi L, Sadoshima J, Sussman MA, Taffet GE, Tanaka H, Torella D, Wang Y, Wang DW. Editors' Preamble to The Journal of Cardiovascular Aging. J Cardiovasc Aging. 2021; 1. PMID: 34327514; PMCID: PMC8318349.
      Citations:    
    14. Chu KM, Jones EM, Meeks JR, Pan AP, Agarwal KL, Taffet GE, Vahidy FS. Decade-Long Nationwide Trends and Disparities in Use of Comfort Care Interventions for Patients With Ischemic Stroke. J Am Heart Assoc. 2021 04 20; 10(8):e019785. PMID: 33823605; PMCID: PMC8174182.
      Citations: 2     Fields:    Translation:Humans
    15. Tovar Perez JE, Ortiz-Urbina J, Heredia CP, Pham TT, Madala S, Hartley CJ, Entman ML, Taffet GE, Reddy AK. Author Correction: Aortic acceleration as a noninvasive index of left ventricular contractility in the mouse. Sci Rep. 2021 Apr 06; 11(1):7859. PMID: 33824374; PMCID: PMC8024311.
      Citations:    Fields:    
    16. Campbell CM, Murphy DR, Taffet GE, Major AB, Ritchie CS, Leff B, Naik AD. Implementing Health Care Quality Measures in Electronic Health Records: A Conceptual Model. J Am Geriatr Soc. 2021 04; 69(4):1079-1085. PMID: 33469940.
      Citations:    Fields:    Translation:HumansPHPublic Health
    17. Perez JET, Ortiz-Urbina J, Heredia CP, Pham TT, Madala S, Hartley CJ, Entman ML, Taffet GE, Reddy AK. Aortic acceleration as a noninvasive index of left ventricular contractility in the mouse. Sci Rep. 2021 01 12; 11(1):536. PMID: 33436716; PMCID: PMC7804023.
      Citations: 1     Fields:    Translation:Animals
    18. Jia X, Sun C, Tang O, Gorlov I, Nambi V, Virani SS, Villareal DT, Taffet GE, Yu B, Bressler J, Boerwinkle E, Windham BG, de Lemos JA, Matsushita K, Selvin E, Michos ED, Hoogeveen RC, Ballantyne CM. Plasma Dehydroepiandrosterone Sulfate and Cardiovascular Disease Risk in Older Men and Women. J Clin Endocrinol Metab. 2020 12 01; 105(12). PMID: 32785663; PMCID: PMC7526732.
      Citations: 5     Fields:    Translation:Humans
    19. Trial J, Diaz Lankenau R, Angelini A, Tovar Perez JE, Taffet GE, Entman ML, Cieslik KA. Treatment with a DC-SIGN ligand reduces macrophage polarization and diastolic dysfunction in the aging female but not male mouse hearts. Geroscience. 2021 04; 43(2):881-899. PMID: 32851570; PMCID: PMC8110645.
      Citations: 2     Fields:    Translation:AnimalsCells
    20. Agarwal KS, Bhimaraj A, Xu J, Bionat S, Pudlo M, Miranda D, Campbell C, Taffet GE. Decreasing Heart Failure Readmissions Among Older Patients With Cognitive Impairment by Engaging Caregivers. J Cardiovasc Nurs. 2020 May/Jun; 35(3):253-261. PMID: 32221145.
      Citations:    Fields:    Translation:Humans
    21. Fiedler LR, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush PA, Bellahcene M, Noseda M, Jarvis A, Newton G, Paiva MA, Harada M, Stuckey DJ, Song W, Habib J, Narasimhan P, Aqil R, Sanmugalingam D, Yan R, Pavanello L, Sano M, Wang SC, Sampson RD, Kanayaganam S, Taffet GE, Michael LH, Entman ML, Tan TH, Harding SE, Low CMR, Tralau-Stewart C, Perrior T, Schneider MD, Faust D. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In?Vivo. Cell Stem Cell. 2020 Mar 05; 26(3):458. PMID: 32142664; PMCID: PMC7059108.
      Citations: 1     Fields:    
    22. Fiedler LR, Chapman K, Xie M, Maifoshie E, Jenkins M, Golforoush PA, Bellahcene M, Noseda M, Jarvis A, Newton G, Paiva MA, Harada M, Stuckey DJ, Song W, Habib J, Narasimhan P, Aqil R, Sanmugalingam D, Yan R, Pavanello L, Sano M, Wang SC, Sampson RD, Kanayaganam S, Taffet GE, Michael LH, Entman ML, Tan TH, Harding SE, Low CMR, Tralau-Stewart C, Perrior T, Schneider MD, Faust D. MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In?Vivo. Cell Stem Cell. 2019 04 04; 24(4):579-591.e12. PMID: 30853557; PMCID: PMC6458995.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    23. Ferguson DP, Monroe TO, Heredia CP, Fleischmann R, Rodney GG, Taffet GE, Fiorotto ML. Postnatal undernutrition alters adult female mouse cardiac structure and function leading to limited exercise capacity. J Physiol. 2019 04; 597(7):1855-1872. PMID: 30730556; PMCID: PMC6441894.
      Citations: 4     Fields:    Translation:Animals
    24. Cieslik KA, Sekhar RV, Granillo A, Reddy A, Medrano G, Heredia CP, Entman ML, Hamilton DJ, Li S, Reineke E, Gupte AA, Zhang A, Taffet GE. Improved Cardiovascular Function in Old Mice After N-Acetyl Cysteine and Glycine Supplemented Diet: Inflammation and Mitochondrial Factors. J Gerontol A Biol Sci Med Sci. 2018 08 10; 73(9):1167-1177. PMID: 29538624; PMCID: PMC6093357.
      Citations: 10     Fields:    Translation:AnimalsCells
    25. Adeola M, Azad R, Kassie GM, Shirkey B, Taffet G, Liebl M, Agarwal K. Multicomponent Interventions Reduce High-Risk Medications for Delirium in Hospitalized Older Adults. J Am Geriatr Soc. 2018 08; 66(8):1638-1645. PMID: 30035315.
      Citations: 5     Fields:    Translation:Humans
    26. Nam DH, Kim E, Benham A, Park HK, Soibam B, Taffet GE, Kaelber JT, Suh JH, Taegtmeyer H, Entman ML, Reineke EL. Transient activation of AMPK preceding left ventricular pressure overload reduces adverse remodeling and preserves left ventricular function. FASEB J. 2019 01; 33(1):711-721. PMID: 30024790; PMCID: PMC6355077.
      Citations: 5     Fields:    Translation:AnimalsCells
    27. Bui NA, Adeola M, Azad R, Swan JT, Agarwal KS, Sharma M, Liebl MG, Taffet GE. Prevalence of Cognitive Impairment Among Elderly Patients Upon Hospital Admission Using Mini-Cog? Assessments Performed by Advanced Pharmacy Practice Experience Students. J Pharm Pract. 2020 Feb; 33(1):21-29. PMID: 29909711.
      Citations: 2     Fields:    Translation:Humans
    28. Saeed A, Nambi V, Sun W, Virani SS, Taffet GE, Deswal A, Selvin E, Matsushita K, Wagenknecht LE, Hoogeveen R, Coresh J, de Lemos JA, Ballantyne CM. Short-Term Global Cardiovascular Disease Risk?Prediction in Older Adults. J Am Coll Cardiol. 2018 06 05; 71(22):2527-2536. PMID: 29535064; PMCID: PMC5984171.
      Citations: 17     Fields:    Translation:Humans
    29. Suh JH, Lai L, Nam D, Kim J, Jo J, Taffet GE, Kim E, Kaelber JT, Lee HK, Entman ML, Cooke JP, Reineke EL. Steroid receptor coactivator-2 (SRC-2) coordinates cardiomyocyte paracrine signaling to promote pressure overload-induced angiogenesis. J Biol Chem. 2017 12 29; 292(52):21643-21652. PMID: 29127200; PMCID: PMC5766961.
      Citations: 4     Fields:    Translation:AnimalsCells
    30. Lam PH, Taffet GE, Ahmed A, Singh S. Cardiac Resynchronization Therapy in Older Adults with?Heart Failure. Heart Fail Clin. 2017 07; 13(3):581-587. PMID: 28602373.
      Citations: 2     Fields:    Translation:Humans
    31. Trial J, Heredia CP, Taffet GE, Entman ML, Cieslik KA. Dissecting the role of myeloid and mesenchymal fibroblasts in age-dependent cardiac fibrosis. Basic Res Cardiol. 2017 07; 112(4):34. PMID: 28478479; PMCID: PMC5591578.
      Citations: 17     Fields:    Translation:AnimalsCells
    32. Granillo A, Pena CA, Pham T, Pandit LM, Taffet GE. Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery. J Vis Exp. 2017 02 20; (120). PMID: 28287520; PMCID: PMC5408887.
      Citations: 4     Fields:    Translation:Animals
    33. Agarwal KS, Kazim R, Xu J, Borson S, Taffet GE. Unrecognized Cognitive Impairment and Its Effect on Heart Failure Readmissions of Elderly Adults. J Am Geriatr Soc. 2016 11; 64(11):2296-2301. PMID: 27676328.
      Citations: 20     Fields:    Translation:Humans
    34. Mayr M, Duerrschmid C, Medrano G, Taffet GE, Wang Y, Entman ML, Haudek SB. TNF/Ang-II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function. Physiol Rep. 2016 Apr; 4(8). PMID: 27125666; PMCID: PMC4848723.
      Citations: 8     Fields:    Translation:AnimalsCells
    35. Crawford JR, Trial J, Nambi V, Hoogeveen RC, Taffet GE, Entman ML. Plasma Levels of Endothelial Microparticles Bearing Monomeric C-reactive Protein are Increased in Peripheral Artery Disease. J Cardiovasc Transl Res. 2016 06; 9(3):184-193. PMID: 26891844; PMCID: PMC4874871.
      Citations: 25     Fields:    Translation:HumansCells
    36. Medrano G, Hermosillo-Rodriguez J, Pham T, Granillo A, Hartley CJ, Reddy A, Osuna PM, Entman ML, Taffet GE. Left Atrial Volume and Pulmonary Artery Diameter Are Noninvasive Measures of Age-Related Diastolic Dysfunction in Mice. J Gerontol A Biol Sci Med Sci. 2016 09; 71(9):1141-50. PMID: 26511013; PMCID: PMC6080426.
      Citations: 12     Fields:    Translation:Animals
    37. Richardson A, Fischer KE, Speakman JR, de Cabo R, Mitchell SJ, Peterson CA, Rabinovitch P, Chiao YA, Taffet G, Miller RA, Bower J, Ingram DK, Ladiges WC, Ikeno Y, Sierra F, Austad SN, Renter?a RC. Measures of Healthspan as Indices of Aging in Mice-A Recommendation. J Gerontol A Biol Sci Med Sci. 2016 Apr; 71(4):427-30. PMID: 26297941; PMCID: PMC4834833.
      Citations: 44     Fields:    Translation:HumansAnimals
    38. Xie L, Pi X, Townley-Tilson WH, Li N, Wehrens XH, Entman ML, Taffet GE, Mishra A, Peng J, Schisler JC, Meissner G, Patterson C. PHD2/3-dependent hydroxylation tunes cardiac response to ?-adrenergic stress via phospholamban. J Clin Invest. 2015 Jul 01; 125(7):2759-71. PMID: 26075818; PMCID: PMC4563684.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    39. Dai X, Hummel SL, Salazar JB, Taffet GE, Zieman S, Schwartz JB. Cardiovascular physiology in the older adults. J Geriatr Cardiol. 2015 May; 12(3):196-201. PMID: 26089840; PMCID: PMC4460159.
      Citations: 24     
    40. Upadhya B, Taffet GE, Cheng CP, Kitzman DW. Heart failure with preserved ejection fraction in the elderly: scope of the problem. J Mol Cell Cardiol. 2015 Jun; 83:73-87. PMID: 25754674; PMCID: PMC5300019.
      Citations: 56     Fields:    Translation:HumansAnimals
    41. Robinson P, Taffet GE, Engineer N, Khumbatta M, Firozgary B, Reynolds C, Pham T, Bulsara T, Firozgary G. Substance P receptor antagonism: a potential novel treatment option for viral-myocarditis. Biomed Res Int. 2015; 2015:645153. PMID: 25821814; PMCID: PMC4363507.
      Citations: 5     Fields:    Translation:Animals
    42. Shah MK, Workeneh B, Taffet GE. Hypernatremia in the geriatric population. Clin Interv Aging. 2014; 9:1987-92. PMID: 25429210; PMCID: PMC4242070.
      Citations: 11     Fields:    Translation:Humans
    43. Pokharel Y, Sun W, de Lemos JA, Taffet GE, Virani SS, Ndumele CE, Mosley TH, Hoogeveen RC, Coresh J, Wright JD, Heiss G, Boerwinkle EA, Bozkurt B, Solomon SD, Ballantyne CM, Nambi V. High-sensitivity troponin T and cardiovascular events in systolic blood pressure categories: atherosclerosis risk in communities study. Hypertension. 2015 Jan; 65(1):78-84. PMID: 25350984; PMCID: PMC4268376.
      Citations: 15     Fields:    Translation:Humans
    44. Li H, Guo Q, Inoue T, Polito VA, Tabuchi K, Hammer RE, Pautler RG, Taffet GE, Zheng H. Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow. Mol Neurodegener. 2014 Aug 09; 9:28. PMID: 25108425; PMCID: PMC4132280.
      Citations: 44     Fields:    Translation:HumansAnimals
    45. Taffet GE, Donohue JF, Altman PR. Considerations for managing chronic obstructive pulmonary disease in the elderly. Clin Interv Aging. 2014; 9:23-30. PMID: 24376347; PMCID: PMC3864989.
      Citations: 29     Fields:    Translation:Humans
    46. Cieslik KA, Trial J, Crawford JR, Taffet GE, Entman ML. Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts. J Mol Cell Cardiol. 2014 May; 70:56-63. PMID: 24184998; PMCID: PMC3995828.
      Citations: 30     Fields:    Translation:HumansCells
    47. Gurha P, Wang T, Larimore AH, Sassi Y, Abreu-Goodger C, Ramirez MO, Reddy AK, Engelhardt S, Taffet GE, Wehrens XH, Entman ML, Rodriguez A. microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. PLoS One. 2013; 8(9):e75882. PMID: 24086656; PMCID: PMC3785418.
      Citations: 31     Fields:    Translation:AnimalsCells
    48. Cieslik KA, Taffet GE, Crawford JR, Trial J, Mejia Osuna P, Entman ML. AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction. J Mol Cell Cardiol. 2013 Oct; 63:26-36. PMID: 23871790; PMCID: PMC3820161.
      Citations: 22     Fields:    Translation:AnimalsCells
    49. Yang EY, Brunner G, Dokainish H, Hartley CJ, Taffet G, Lakkis N, Taylor AA, Misra A, McCulloch ML, Morrisett JD, Virani SS, Ballantyne CM, Nagueh SF, Nambi V. Application of speckle-tracking in the evaluation of carotid artery function in subjects with hypertension and diabetes. J Am Soc Echocardiogr. 2013 Aug; 26(8):901-909.e1. PMID: 23759168; PMCID: PMC3725197.
      Citations: 6     Fields:    Translation:Humans
    50. Wagle KC, Rowan PJ, Poon OY, Kunik ME, Taffet GE, Braun UK. Initiation of cholinesterase inhibitors in an inpatient setting. Am J Alzheimers Dis Other Demen. 2013 Jun; 28(4):377-83. PMID: 23702586; PMCID: PMC10852669.
      Citations: 1     Fields:    Translation:Humans
    51. Reddy AK, Hartley CJ, Pham TT, Darlington G, Entman ML, Taffet GE. Young little mice express a premature cardiovascular aging phenotype. J Gerontol A Biol Sci Med Sci. 2014 Feb; 69(2):152-9. PMID: 23682160; PMCID: PMC4038241.
      Citations: 4     Fields:    Translation:Animals
    52. Swan JT, Wagle KC, Thompson-Moore N, Taffet GE. Incidence of cholinesterase inhibitor therapy initiation among hospitalized patients. J Hosp Med. 2013 Jun; 8(6):304-8. PMID: 23526817.
      Citations:    Fields:    Translation:Humans
    53. Duerrschmid C, Crawford JR, Reineke E, Taffet GE, Trial J, Entman ML, Haudek SB. TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis. J Mol Cell Cardiol. 2013 Apr; 57:59-67. PMID: 23337087; PMCID: PMC3593947.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    54. Cieslik KA, Trial J, Carlson S, Taffet GE, Entman ML. Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J. 2013 Apr; 27(4):1761-71. PMID: 23303205; PMCID: PMC3606539.
      Citations: 23     Fields:    Translation:AnimalsCells
    55. Reineke EL, York B, Stashi E, Chen X, Tsimelzon A, Xu J, Newgard CB, Taffet GE, Taegtmeyer H, Entman ML, O'Malley BW. SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One. 2012; 7(12):e53395. PMID: 23300926; PMCID: PMC3534027.
      Citations: 17     Fields:    Translation:AnimalsCells
    56. Kerfoot BP, Baker H, Pangaro L, Agarwal K, Taffet G, Mechaber AJ, Armstrong EG. An online spaced-education game to teach and assess medical students: a multi-institutional prospective trial. Acad Med. 2012 Oct; 87(10):1443-9. PMID: 22914524.
      Citations: 19     Fields:    Translation:HumansCTClinical Trials
    57. Gurha P, Abreu-Goodger C, Wang T, Ramirez MO, Drumond AL, van Dongen S, Chen Y, Bartonicek N, Enright AJ, Lee B, Kelm RJ, Reddy AK, Taffet GE, Bradley A, Wehrens XH, Entman ML, Rodriguez A. Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation. 2012 Jun 05; 125(22):2751-61. PMID: 22570371; PMCID: PMC3503489.
      Citations: 80     Fields:    Translation:AnimalsCells
    58. Mills WL, Roush RE, Moye J, Kunik ME, Wilson NL, Taffet GE, Naik AD. An educational program to assist clinicians in identifying elder investment fraud and financial exploitation. Gerontol Geriatr Educ. 2012; 33(4):351-63. PMID: 23095220.
      Citations: 3     Fields:    Translation:Humans
    59. Wagle KC, Taffet GE, Natali B. Cholinesterase inhibitor initiation in hospital setting. J Am Geriatr Soc. 2011 Oct; 59(10):1988-9. PMID: 22091527.
      Citations:    Fields:    Translation:Humans
    60. Lloyd EE, Crossland RF, Phillips SC, Marrelli SP, Reddy AK, Taffet GE, Hartley CJ, Bryan RM. Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice. Hypertension. 2011 Oct; 58(4):672-8. PMID: 21876070; PMCID: PMC3205080.
      Citations: 20     Fields:    Translation:Animals
    61. Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. Am J Clin Nutr. 2011 Sep; 94(3):847-53. PMID: 21795440; PMCID: PMC3155927.
      Citations: 98     Fields:    Translation:HumansCellsCTClinical Trials
    62. Xu J, Lin SC, Chen J, Miao Y, Taffet GE, Entman ML, Wang Y. CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H538-47. PMID: 21572015; PMCID: PMC3154672.
      Citations: 51     Fields:    Translation:AnimalsCells
    63. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Doppler velocity measurements from large and small arteries of mice. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H269-78. PMID: 21572013; PMCID: PMC3154663.
      Citations: 21     Fields:    Translation:Animals
    64. Cheema FN, Abraham NS, Berger DH, Albo D, Taffet GE, Naik AD. Novel approaches to perioperative assessment and intervention may improve long-term outcomes after colorectal cancer resection in older adults. Ann Surg. 2011 May; 253(5):867-74. PMID: 21183846.
      Citations: 19     Fields:    Translation:Humans
    65. Cieslik KA, Taffet GE, Carlson S, Hermosillo J, Trial J, Entman ML. Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart. J Mol Cell Cardiol. 2011 Jan; 50(1):248-56. PMID: 20974150; PMCID: PMC3019252.
      Citations: 64     Fields:    Translation:AnimalsCells
    66. Hartley CJ, Reddy AK, Madala S, Entman ML, Taffet GE. Feasibility of dual Doppler velocity measurements to estimate volume pulsations of an arterial segment. Ultrasound Med Biol. 2010 Jul; 36(7):1169-75. PMID: 20620703; PMCID: PMC2904320.
      Citations: 2     Fields:    Translation:HumansAnimals
    67. Haudek SB, Cheng J, Du J, Wang Y, Hermosillo-Rodriguez J, Trial J, Taffet GE, Entman ML. Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J Mol Cell Cardiol. 2010 Sep; 49(3):499-507. PMID: 20488188; PMCID: PMC2917526.
      Citations: 91     Fields:    Translation:AnimalsCells
    68. Alexander NB, Taffet GE, Horne FM, Eldadah BA, Ferrucci L, Nayfield S, Studenski S. Bedside-to-Bench conference: research agenda for idiopathic fatigue and aging. J Am Geriatr Soc. 2010 May; 58(5):967-75. PMID: 20722821; PMCID: PMC4540791.
      Citations: 69     Fields:    Translation:HumansCells
    69. Namiranian K, Lloyd EE, Crossland RF, Marrelli SP, Taffet GE, Reddy AK, Hartley CJ, Bryan RM. Cerebrovascular responses in mice deficient in the potassium channel, TREK-1. Am J Physiol Regul Integr Comp Physiol. 2010 Aug; 299(2):R461-9. PMID: 20357027; PMCID: PMC2928619.
      Citations: 18     Fields:    Translation:AnimalsCells
    70. Smiechowska J, Utech A, Taffet G, Hayes T, Marcelli M, Garcia JM. Adipokines in patients with cancer anorexia and cachexia. J Investig Med. 2010 Mar; 58(3):554-9. PMID: 20215915.
      Citations: 23     Fields:    Translation:Humans
    71. Chintalgattu V, Ai D, Langley RR, Zhang J, Bankson JA, Shih TL, Reddy AK, Coombes KR, Daher IN, Pati S, Patel SS, Pocius JS, Taffet GE, Buja LM, Entman ML, Khakoo AY. Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. J Clin Invest. 2010 Feb; 120(2):472-84. PMID: 20071776; PMCID: PMC2810076.
      Citations: 76     Fields:    Translation:AnimalsCells
    72. Hartley CJ, Reddy AK, Michael LH, Entman ML, Chintalagattu V, Khakoo AY, Taffet GE. Coronary flow reserve in mice: effects of age, coronary disease, and vascular loading. Annu Int Conf IEEE Eng Med Biol Soc. 2010; 2010:3780-3. PMID: 21096875; PMCID: PMC3341612.
      Citations: 8     Fields:    Translation:Animals
    73. Reddy AK, Madala S, Jones AD, Caro WA, Eberth JF, Pham TT, Taffet GE, Hartley CJ. Multichannel pulsed Doppler signal processing for vascular measurements in mice. Ultrasound Med Biol. 2009 Dec; 35(12):2042-54. PMID: 19854566; PMCID: PMC2900799.
      Citations: 9     Fields:    Translation:Animals
    74. Hyman DJ, Taffet GE. Blood pressure control in the elderly: can you have too much of a good thing? Curr Hypertens Rep. 2009 Oct; 11(5):337-42. PMID: 19737450.
      Citations: 5     Fields:    Translation:Humans
    75. Reddy AK, Namiranian K, Lloyd EE, Bryan RM, Taffet GE, Hartley CJ. Effect of isoflurane on aortic impedance in mice. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:1104-5. PMID: 19964748; PMCID: PMC3341611.
      Citations: 8     Fields:    Translation:Animals
    76. Hartley CJ, Reddy AK, Michael LH, Entman ML, Taffet GE. Coronary flow reserve as an index of cardiac function in mice with cardiovascular abnormalities. Annu Int Conf IEEE Eng Med Biol Soc. 2009; 2009:1094-7. PMID: 19963485; PMCID: PMC3341618.
      Citations: 6     Fields:    Translation:HumansAnimals
    77. Bujak M, Kweon HJ, Chatila K, Li N, Taffet G, Frangogiannis NG. Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol. 2008 Apr 08; 51(14):1384-92. PMID: 18387441; PMCID: PMC3348616.
      Citations: 92     Fields:    Translation:AnimalsCells
    78. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, Taffet GE. Doppler estimation of reduced coronary flow reserve in mice with pressure overload cardiac hypertrophy. Ultrasound Med Biol. 2008 Jun; 34(6):892-901. PMID: 18255218; PMCID: PMC2453594.
      Citations: 33     Fields:    Translation:Animals
    79. Reddy AK, Taffet GE, Hartley CJ. Aortic impedance in Little mice. Annu Int Conf IEEE Eng Med Biol Soc. 2008; 2008:1397-8. PMID: 19162929; PMCID: PMC3345796.
      Citations:    Fields:    Translation:Animals
    80. Hartley CJ, Reddy AK, Taffet GE. In-vitro evaluation of sensors and amplifiers to measure left ventricular pressure in mice. Annu Int Conf IEEE Eng Med Biol Soc. 2008; 2008:965-8. PMID: 19162818; PMCID: PMC3341624.
      Citations: 2     Fields:    Translation:Animals
    81. Reddy AK, Amador-Noguez D, Darlington GJ, Scholz BA, Michael LH, Hartley CJ, Entman ML, Taffet GE. Cardiac function in young and old Little mice. J Gerontol A Biol Sci Med Sci. 2007 Dec; 62(12):1319-25. PMID: 18166681; PMCID: PMC2771398.
      Citations: 18     Fields:    Translation:Animals
    82. Bujak M, Ren G, Kweon HJ, Dobaczewski M, Reddy A, Taffet G, Wang XF, Frangogiannis NG. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation. 2007 Nov 06; 116(19):2127-38. PMID: 17967775.
      Citations: 171     Fields:    Translation:AnimalsCells
    83. Wang GS, Kearney DL, De Biasi M, Taffet G, Cooper TA. Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy. J Clin Invest. 2007 Oct; 117(10):2802-11. PMID: 17823658; PMCID: PMC1964514.
      Citations: 106     Fields:    Translation:AnimalsCells
    84. Haudek SB, Taffet GE, Schneider MD, Mann DL. TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. J Clin Invest. 2007 Sep; 117(9):2692-701. PMID: 17694177; PMCID: PMC1937497.
      Citations: 101     Fields:    Translation:HumansAnimalsCells
    85. Duran JR, Taffet G. Coronary microvascular dysfunction. N Engl J Med. 2007 May 31; 356(22):2324-5; author reply 2325. PMID: 17538094.
      Citations: 3     Fields:    Translation:Humans
    86. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, Taffet GE. Effects of isoflurane on coronary blood flow velocity in young, old and ApoE(-/-) mice measured by Doppler ultrasound. Ultrasound Med Biol. 2007 Apr; 33(4):512-21. PMID: 17346873; PMCID: PMC2048667.
      Citations: 29     Fields:    Translation:Animals
    87. Frangogiannis NG, Dewald O, Xia Y, Ren G, Haudek S, Leucker T, Kraemer D, Taffet G, Rollins BJ, Entman ML. Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation. 2007 Feb 06; 115(5):584-92. PMID: 17283277.
      Citations: 125     Fields:    Translation:AnimalsCells
    88. Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Schneider MD, M?kel? TP. M?nage-?-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 2007 Feb; 5(2):129-42. PMID: 17276355.
      Citations: 25     Fields:    Translation:AnimalsCells
    89. Zymek P, Nah DY, Bujak M, Ren G, Koerting A, Leucker T, Huebener P, Taffet G, Entman M, Frangogiannis NG. Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res. 2007 May 01; 74(2):313-22. PMID: 17188669; PMCID: PMC1924681.
      Citations: 32     Fields:    Translation:AnimalsCells
    90. Xie M, Zhang D, Dyck JR, Li Y, Zhang H, Morishima M, Mann DL, Taffet GE, Baldini A, Khoury DS, Schneider MD. A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17378-83. PMID: 17085580; PMCID: PMC1859937.
      Citations: 144     Fields:    Translation:AnimalsCells
    91. Kannankeril PJ, Mitchell BM, Goonasekera SA, Chelu MG, Zhang W, Sood S, Kearney DL, Danila CI, De Biasi M, Wehrens XH, Pautler RG, Roden DM, Taffet GE, Dirksen RT, Anderson ME, Hamilton SL. Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A. 2006 Aug 08; 103(32):12179-84. PMID: 16873551; PMCID: PMC1567715.
      Citations: 77     Fields:    Translation:Animals
    92. Thakker GD, Frangogiannis NG, Bujak M, Zymek P, Gaubatz JW, Reddy AK, Taffet G, Michael LH, Entman ML, Ballantyne CM. Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol. 2006 Nov; 291(5):H2504-14. PMID: 16731644.
      Citations: 49     Fields:    Translation:Animals
    93. Zhang YM, Bo J, Taffet GE, Chang J, Shi J, Reddy AK, Michael LH, Schneider MD, Entman ML, Schwartz RJ, Wei L. Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis. FASEB J. 2006 May; 20(7):916-25. PMID: 16675849.
      Citations: 113     Fields:    Translation:Animals
    94. Reddy AK, Taffet GE, Li YH, Lim SW, Pham TT, Pocius JS, Entman ML, Michael LH, Hartley CJ. Pulsed Doppler signal processing for use in mice: applications. IEEE Trans Biomed Eng. 2005 Oct; 52(10):1771-83. PMID: 16235663.
      Citations: 24     Fields:    Translation:Animals
    95. Schillinger KJ, Tsai SY, Taffet GE, Reddy AK, Marian AJ, Entman ML, Oka K, Chan L, O'Malley BW. Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13789-94. PMID: 16162668; PMCID: PMC1236585.
      Citations: 22     Fields:    Translation:AnimalsCells
    96. Ladd AN, Taffet G, Hartley C, Kearney DL, Cooper TA. Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Mol Cell Biol. 2005 Jul; 25(14):6267-78. PMID: 15988035; PMCID: PMC1168813.
      Citations: 42     Fields:    Translation:AnimalsCells
    97. Garcia-Touza M, Hijazi RA, Taffet G, Epner D, Mann D, Smith RG, Cunningham GR, Marcelli M, Garcia JM. Active ghrelin levels and active to total ghrelin ratio in cancer-induced cachexia. J Clin Endocrinol Metab. 2005 May; 90(5):2920-6. PMID: 15713718.
      Citations: 79     Fields:    Translation:Humans
    98. Sidhu JS, Rajawat YS, Rami TG, Gollob MH, Wang Z, Yuan R, Marian AJ, DeMayo FJ, Weilbacher D, Taffet GE, Davies JK, Carling D, Khoury DS, Roberts R. Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome. Circulation. 2005 Jan 04; 111(1):21-9. PMID: 15611370; PMCID: PMC2908313.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    99. Dewald O, Frangogiannis NG, Zoerlein MP, Duerr GD, Taffet G, Michael LH, Welz A, Entman ML. A murine model of ischemic cardiomyopathy induced by repetitive ischemia and reperfusion. Thorac Cardiovasc Surg. 2004 Oct; 52(5):305-11. PMID: 15470614.
      Citations: 11     Fields:    Translation:Animals
    100. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Noninvasive ultrasonic measurement of arterial wall motion in mice. Am J Physiol Heart Circ Physiol. 2004 Sep; 287(3):H1426-32. PMID: 15317682.
      Citations: 9     Fields:    Translation:Animals
    101. Sano M, Wang SC, Shirai M, Scaglia F, Xie M, Sakai S, Tanaka T, Kulkarni PA, Barger PM, Youker KA, Taffet GE, Hamamori Y, Michael LH, Craigen WJ, Schneider MD. Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure. EMBO J. 2004 Sep 01; 23(17):3559-69. PMID: 15297879; PMCID: PMC516624.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
    102. Appleton GO, Li Y, Taffet GE, Hartley CJ, Michael LH, Entman ML, Roberts R, Khoury DS. Determinants of cardiac electrophysiological properties in mice. J Interv Card Electrophysiol. 2004 Aug; 11(1):5-14. PMID: 15273447.
      Citations: 18     Fields:    Translation:Animals
    103. Wei L, Taffet GE, Khoury DS, Bo J, Li Y, Yatani A, Delaughter MC, Klevitsky R, Hewett TE, Robbins J, Michael LH, Schneider MD, Entman ML, Schwartz RJ. Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. FASEB J. 2004 May; 18(7):857-9. PMID: 15033930.
      Citations: 20     Fields:    Translation:AnimalsCells
    104. Weisleder N, Taffet GE, Capetanaki Y. Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy. Proc Natl Acad Sci U S A. 2004 Jan 20; 101(3):769-74. PMID: 14715896; PMCID: PMC321756.
      Citations: 46     Fields:    Translation:Animals
    105. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Noninvasive ultrasonic measurement of arterial wall motion in mice. Conf Proc IEEE Eng Med Biol Soc. 2004; 2004:3688-91. PMID: 17271094.
      Citations: 2     Fields:    
    106. Li YH, Reddy AK, Ochoa LN, Pham TT, Hartley CJ, Michael LH, Entman ML, Taffet GE. Effect of age on peripheral vascular response to transverse aortic banding in mice. J Gerontol A Biol Sci Med Sci. 2003 Oct; 58(10):B895-9. PMID: 14570855.
      Citations: 9     Fields:    Translation:Animals
    107. Li YH, Reddy AK, Taffet GE, Michael LH, Entman ML, Hartley CJ. Doppler evaluation of peripheral vascular adaptations to transverse aortic banding in mice. Ultrasound Med Biol. 2003 Sep; 29(9):1281-9. PMID: 14553805.
      Citations: 21     Fields:    Translation:Animals
    108. Reddy AK, Li YH, Pham TT, Ochoa LN, Trevino MT, Hartley CJ, Michael LH, Entman ML, Taffet GE. Measurement of aortic input impedance in mice: effects of age on aortic stiffness. Am J Physiol Heart Circ Physiol. 2003 Oct; 285(4):H1464-70. PMID: 12775560.
      Citations: 42     Fields:    Translation:Animals
    109. Oh H, Wang SC, Prahash A, Sano M, Moravec CS, Taffet GE, Michael LH, Youker KA, Entman ML, Schneider MD. Telomere attrition and Chk2 activation in human heart failure. Proc Natl Acad Sci U S A. 2003 Apr 29; 100(9):5378-83. PMID: 12702777; PMCID: PMC154353.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    110. Reddy AK, Taffet GE, Madala S, Michael LH, Entman ML, Hartley CJ. Noninvasive blood pressure measurement in mice using pulsed Doppler ultrasound. Ultrasound Med Biol. 2003 Mar; 29(3):379-85. PMID: 12706189.
      Citations: 9     Fields:    Translation:Animals
    111. Dewald O, Frangogiannis NG, Zoerlein M, Duerr GD, Klemm C, Knuefermann P, Taffet G, Michael LH, Crapo JD, Welz A, Entman ML. Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species. Proc Natl Acad Sci U S A. 2003 Mar 04; 100(5):2700-5. PMID: 12586861; PMCID: PMC151404.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    112. Baumgarten G, Knuefermann P, Kalra D, Gao F, Taffet GE, Michael L, Blackshear PJ, Carballo E, Sivasubramanian N, Mann DL. Load-dependent and -independent regulation of proinflammatory cytokine and cytokine receptor gene expression in the adult mammalian heart. Circulation. 2002 May 07; 105(18):2192-7. PMID: 11994254.
      Citations: 35     Fields:    Translation:AnimalsCells
    113. Minamino T, Yujiri T, Terada N, Taffet GE, Michael LH, Johnson GL, Schneider MD. MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3866-71. PMID: 11891332; PMCID: PMC122615.
      Citations: 31     Fields:    Translation:AnimalsCells
    114. Gould KE, Taffet GE, Michael LH, Christie RM, Konkol DL, Pocius JS, Zachariah JP, Chaupin DF, Daniel SL, Sandusky GE, Hartley CJ, Entman ML. Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure. Am J Physiol Heart Circ Physiol. 2002 Feb; 282(2):H615-21. PMID: 11788410.
      Citations: 33     Fields:    Translation:Animals
    115. Hartley CJ, Taffet GE, Reddy AK, Entman ML, Michael LH. Noninvasive cardiovascular phenotyping in mice. ILAR J. 2002; 43(3):147-58. PMID: 12105382.
      Citations: 25     Fields:    Translation:Animals
    116. Schildmeyer LA, Braun R, Taffet G, Debiasi M, Burns AE, Bradley A, Schwartz RJ. Impaired vascular contractility and blood pressure homeostasis in the smooth muscle alpha-actin null mouse. FASEB J. 2000 Nov; 14(14):2213-20. PMID: 11053242.
      Citations: 90     Fields:    Translation:Animals
    117. Kurrelmeyer KM, Michael LH, Baumgarten G, Taffet GE, Peschon JJ, Sivasubramanian N, Entman ML, Mann DL. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci U S A. 2000 May 09; 97(10):5456-61. PMID: 10779546; PMCID: PMC25850.
      Citations: 113     Fields:    Translation:Animals
    118. Zhang D, Gaussin V, Taffet GE, Belaguli NS, Yamada M, Schwartz RJ, Michael LH, Overbeek PA, Schneider MD. TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. Nat Med. 2000 May; 6(5):556-63. PMID: 10802712.
      Citations: 117     Fields:    Translation:AnimalsCells
    119. Nossuli TO, Lakshminarayanan V, Baumgarten G, Taffet GE, Ballantyne CM, Michael LH, Entman ML. A chronic mouse model of myocardial ischemia-reperfusion: essential in cytokine studies. Am J Physiol Heart Circ Physiol. 2000 Apr; 278(4):H1049-55. PMID: 10749697.
      Citations: 67     Fields:    Translation:Animals
    120. Delaughter MC, Taffet GE, Fiorotto ML, Entman ML, Schwartz RJ. Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice. FASEB J. 1999 Nov; 13(14):1923-9. PMID: 10544175.
      Citations: 43     Fields:    Translation:HumansAnimals
    121. Milner DJ, Taffet GE, Wang X, Pham T, Tamura T, Hartley C, Gerdes AM, Capetanaki Y. The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function. J Mol Cell Cardiol. 1999 Nov; 31(11):2063-76. PMID: 10591032.
      Citations: 58     Fields:    Translation:HumansAnimals
    122. Michael LH, Ballantyne CM, Zachariah JP, Gould KE, Pocius JS, Taffet GE, Hartley CJ, Pham TT, Daniel SL, Funk E, Entman ML. Myocardial infarction and remodeling in mice: effect of reperfusion. Am J Physiol. 1999 08; 277(2 Pt 2):H660-8. PMID: 10444492.
      Citations: 54     Fields:    Translation:Animals
    123. Hartley CJ, Lacy JL, Dai D, Nayak N, Taffet GE, Entman ML, Michael LH. Functional cardiac imaging in mice using Ta-178. Nat Med. 1999 Feb; 5(2):237-9. PMID: 9930875.
      Citations: 2     Fields:    Translation:Animals
    124. Bick RJ, Van Winkle WB, Taffet GE. Cardiac sarcoplasmic reticulum membrane lipid asymmetries. Ann N Y Acad Sci. 1998 Sep 16; 853:365-7. PMID: 10603981.
      Citations: 1     Fields:    Translation:AnimalsCells
    125. Bick RJ, Buja LM, Van Winkle WB, Taffet GE. Membrane asymmetry in isolated canine cardiac sarcoplasmic reticulum: comparison with skeletal muscle sarcoplasmic reticulum. J Membr Biol. 1998 Jul 15; 164(2):169-75. PMID: 9662560.
      Citations: 14     Fields:    Translation:AnimalsCells
    126. Taffet GE, Pham TT, Hartley CJ. The age-associated alterations in late diastolic function in mice are improved by caloric restriction. J Gerontol A Biol Sci Med Sci. 1997 Nov; 52(6):B285-90. PMID: 9402929.
      Citations: 35     Fields:    Translation:Animals
    127. Kapadia SR, Oral H, Lee J, Nakano M, Taffet GE, Mann DL. Hemodynamic regulation of tumor necrosis factor-alpha gene and protein expression in adult feline myocardium. Circ Res. 1997 Aug; 81(2):187-95. PMID: 9242179.
      Citations: 61     Fields:    Translation:Animals
    128. Guerra-Garcia H, Taffet G, Protas EJ. Considerations related to disability and exercise in elderly women with congestive heart failure. J Cardiovasc Nurs. 1997 Jul; 11(4):60-74. PMID: 9200020.
      Citations:    Fields:    Translation:Humans
    129. Hartley CJ, Taffet GE, Michael LH, Pham TT, Entman ML. Noninvasive determination of pulse-wave velocity in mice. Am J Physiol. 1997 Jul; 273(1 Pt 2):H494-500. PMID: 9249523.
      Citations: 46     Fields:    Translation:Animals
    130. Taffet GE, Michael LA, Tate CA. Exercise training improves lusitropy by isoproterenol in papillary muscles from aged rats. J Appl Physiol (1985). 1996 Oct; 81(4):1488-94. PMID: 8904558.
      Citations: 4     Fields:    Translation:Animals
    131. Tate CA, Helgason T, Hyek MF, McBride RP, Chen M, Richardson MA, Taffet GE. SERCA2a and mitochondrial cytochrome oxidase expression are increased in hearts of exercise-trained old rats. Am J Physiol. 1996 Jul; 271(1 Pt 2):H68-72. PMID: 8760159.
      Citations: 15     Fields:    Translation:AnimalsCells
    132. Taffet GE, Hartley CJ, Wen X, Pham T, Michael LH, Entman ML. Noninvasive indexes of cardiac systolic and diastolic function in hyperthyroid and senescent mouse. Am J Physiol. 1996 Jun; 270(6 Pt 2):H2204-9. PMID: 8764275.
      Citations: 18     Fields:    Translation:Animals
    133. Beer RJ, Teasdale TA, Ghusn HF, Taffet GE. Estimation of severity of illness with APACHE II: age-related implications in cardiac arrest outcomes. Resuscitation. 1994 May; 27(3):189-95. PMID: 8079052.
      Citations: 6     Fields:    Translation:Humans
    134. Tate CA, Hyek MF, Taffet GE. Mechanisms for the responses of cardiac muscle to physical activity in old age. Med Sci Sports Exerc. 1994 May; 26(5):561-7. PMID: 8007803.
      Citations: 3     Fields:    Translation:HumansCells
    135. McMillin JB, Taffet GE, Taegtmeyer H, Hudson EK, Tate CA. Mitochondrial metabolism and substrate competition in the aging Fischer rat heart. Cardiovasc Res. 1993 Dec; 27(12):2222-8. PMID: 8313432.
      Citations: 27     Fields:    Translation:AnimalsCells
    136. Tate C, Hamra M, Shin G, Taffet G, McBride P, Entman M. Canine cardiac sarcoplasmic reticulum is not altered with endurance exercise training. Med Sci Sports Exerc. 1993 Nov; 25(11):1246-57. PMID: 8289611.
      Citations: 5     Fields:    Translation:AnimalsCells
    137. Taffet GE, Tate CA. CaATPase content is lower in cardiac sarcoplasmic reticulum isolated from old rats. Am J Physiol. 1993 May; 264(5 Pt 2):H1609-14. PMID: 8498573.
      Citations: 16     Fields:    Translation:AnimalsCells
    138. Taffet GE, Pham TT, Bick DL, Entman ML, Pownall HJ, Bick RJ. The calcium uptake of the rat heart sarcoplasmic reticulum is altered by dietary lipid. J Membr Biol. 1993 Jan; 131(1):35-42. PMID: 8381872.
      Citations: 17     Fields:    Translation:AnimalsCells
    139. Taffet GE, Tate CA. The MgATPase activity of rat cardiac sarcoplasmic reticulum is a function of the calcium ATPase protein. Arch Biochem Biophys. 1992 Dec; 299(2):287-94. PMID: 1444468.
      Citations: 1     Fields:    Translation:AnimalsCells
    140. Taffet GE, Teasdale TA, Bleyer AJ, Kutka NJ, Luchi RJ. Survival of elderly men with congestive heart failure. Age Ageing. 1992 Jan; 21(1):49-55. PMID: 1553860.
      Citations: 7     Fields:    Translation:Humans
    141. Tate CA, Hyek MF, Taffet GE. The role of calcium in the energetics of contracting skeletal muscle. Sports Med. 1991 Sep; 12(3):208-17. PMID: 1664541.
      Citations: 6     Fields:    Translation:HumansCells
    142. Tate CA, Shin G, Walseth TF, Taffet GE, Bick RJ, Entman ML. Nucleotide specificity of cardiac sarcoplasmic reticulum. Inhibition of GTPase activity by ATP analogue in fluorescein isothiocyanate-modified calcium ATPase. J Biol Chem. 1991 Aug 25; 266(24):16165-70. PMID: 1831455.
      Citations: 1     Fields:    Translation:AnimalsCells
    143. Luchi RJ, Taffet GE, Teasdale TA. Congestive heart failure in the elderly. J Am Geriatr Soc. 1991 Aug; 39(8):810-25. PMID: 2071813.
      Citations: 10     Fields:    Translation:Humans
    144. Schonwetter RS, Teasdale TA, Taffet G, Robinson BE, Luchi RJ. Educating the elderly: cardiopulmonary resuscitation decisions before and after intervention. J Am Geriatr Soc. 1991 Apr; 39(4):372-7. PMID: 2010586.
      Citations: 16     Fields:    Translation:Humans
    145. Tate CA, Taffet GE, Hudson EK, Blaylock SL, McBride RP, Michael LH. Enhanced calcium uptake of cardiac sarcoplasmic reticulum in exercise-trained old rats. Am J Physiol. 1990 Feb; 258(2 Pt 2):H431-5. PMID: 2137986.
      Citations: 27     Fields:    Translation:AnimalsCells
    146. Tate CA, Taffet GE. The regulatory role of calcium in striated muscle. Med Sci Sports Exerc. 1989 Aug; 21(4):393-8. PMID: 2674591.
      Citations:    Fields:    Translation:HumansCells
    147. Taffet GE, Teasdale TA, Luchi RJ. In-hospital cardiopulmonary resuscitation. JAMA. 1988 Oct 14; 260(14):2069-72. PMID: 3270334.
      Citations: 37     Fields:    Translation:Humans
    148. Teasdale TA, Taffet GE, Luchi RJ, Adam E. Urinary incontinence in a community-residing elderly population. J Am Geriatr Soc. 1988 Jul; 36(7):600-6. PMID: 3385112.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    149. Brown DL, Musher DM, Taffet GE. Hematogenously acquired Aspergillus vertebral osteomyelitis in seemingly immunocompetent drug addicts. West J Med. 1987 Jul; 147(1):84-5. PMID: 3321709; PMCID: PMC1025835.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
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