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GEORGE E TAFFET

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address1200 BINZ, SUITE 720
HOUSTON TX 77004
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Physiology & Biophysics
    DivisionMolecular Physiology & Biophysics

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentHuffington Center on Aging
    DivisionHuffington Ctr on Aging


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mayr M, Duerrschmid C, Medrano G, Taffet GE, Wang Y, Entman ML, Haudek SB. TNF/Ang-II synergy is obligate for fibroinflammatory pathology, but not for changes in cardiorenal function. Physiol Rep. 2016 Apr; 4(8). PMID: 27125666; PMCID: PMC4848723.
    2. Crawford JR, Trial J, Nambi V, Hoogeveen RC, Taffet GE, Entman ML. Plasma Levels of Endothelial Microparticles Bearing Monomeric C-reactive Protein are Increased in Peripheral Artery Disease. J Cardiovasc Transl Res. 2016 Jun; 9(3):184-93. PMID: 26891844; PMCID: PMC4874871 [Available on 06/01/17].
    3. Medrano G, Hermosillo-Rodriguez J, Pham T, Granillo A, Hartley CJ, Reddy A, Osuna PM, Entman ML, Taffet GE. Left Atrial Volume and Pulmonary Artery Diameter Are Noninvasive Measures of Age-Related Diastolic Dysfunction in Mice. J Gerontol A Biol Sci Med Sci. 2016 Sep; 71(9):1141-50. PMID: 26511013.
      View in: PubMed
    4. Xie L, Pi X, Townley-Tilson WH, Li N, Wehrens XH, Entman ML, Taffet GE, Mishra A, Peng J, Schisler JC, Meissner G, Patterson C. PHD2/3-dependent hydroxylation tunes cardiac response to ?-adrenergic stress via phospholamban. J Clin Invest. 2015 Jul 1; 125(7):2759-71. PMID: 26075818.
      View in: PubMed
    5. Dai X, Hummel SL, Salazar JB, Taffet GE, Zieman S, Schwartz JB. Cardiovascular physiology in the older adults. J Geriatr Cardiol. 2015 May; 12(3):196-201. PMID: 26089840.
      View in: PubMed
    6. Upadhya B, Taffet GE, Cheng CP, Kitzman DW. Heart failure with preserved ejection fraction in the elderly: scope of the problem. J Mol Cell Cardiol. 2015 Jun; 83:73-87. PMID: 25754674.
      View in: PubMed
    7. Robinson P, Taffet GE, Engineer N, Khumbatta M, Firozgary B, Reynolds C, Pham T, Bulsara T, Firozgary G. Substance P receptor antagonism: a potential novel treatment option for viral-myocarditis. Biomed Res Int. 2015; 2015:645153. PMID: 25821814; PMCID: PMC4363507.
    8. Shah MK, Workeneh B, Taffet GE. Hypernatremia in the geriatric population. Clin Interv Aging. 2014; 9:1987-92. PMID: 25429210; PMCID: PMC4242070.
    9. Pokharel Y, Sun W, de Lemos JA, Taffet GE, Virani SS, Ndumele CE, Mosley TH, Hoogeveen RC, Coresh J, Wright JD, Heiss G, Boerwinkle EA, Bozkurt B, Solomon SD, Ballantyne CM, Nambi V. High-sensitivity troponin T and cardiovascular events in systolic blood pressure categories: atherosclerosis risk in communities study. Hypertension. 2015 Jan; 65(1):78-84. PMID: 25350984; PMCID: PMC4268376.
    10. Li H, Guo Q, Inoue T, Polito VA, Tabuchi K, Hammer RE, Pautler RG, Taffet GE, Zheng H. Vascular and parenchymal amyloid pathology in an Alzheimer disease knock-in mouse model: interplay with cerebral blood flow. Mol Neurodegener. 2014; 9:28. PMID: 25108425; PMCID: PMC4132280.
    11. Taffet GE, Donohue JF, Altman PR. Considerations for managing chronic obstructive pulmonary disease in the elderly. Clin Interv Aging. 2014; 9:23-30. PMID: 24376347; PMCID: PMC3864989.
    12. Cieslik KA, Trial J, Crawford JR, Taffet GE, Entman ML. Adverse fibrosis in the aging heart depends on signaling between myeloid and mesenchymal cells; role of inflammatory fibroblasts. J Mol Cell Cardiol. 2014 May; 70:56-63. PMID: 24184998; PMCID: PMC3995828.
    13. Gurha P, Wang T, Larimore AH, Sassi Y, Abreu-Goodger C, Ramirez MO, Reddy AK, Engelhardt S, Taffet GE, Wehrens XH, Entman ML, Rodriguez A. microRNA-22 promotes heart failure through coordinate suppression of PPAR/ERR-nuclear hormone receptor transcription. PLoS One. 2013; 8(9):e75882. PMID: 24086656; PMCID: PMC3785418.
    14. Cieslik KA, Taffet GE, Crawford JR, Trial J, Mejia Osuna P, Entman ML. AICAR-dependent AMPK activation improves scar formation in the aged heart in a murine model of reperfused myocardial infarction. J Mol Cell Cardiol. 2013 Oct; 63:26-36. PMID: 23871790; PMCID: PMC3820161.
    15. Yang EY, Brunner G, Dokainish H, Hartley CJ, Taffet G, Lakkis N, Taylor AA, Misra A, McCulloch ML, Morrisett JD, Virani SS, Ballantyne CM, Nagueh SF, Nambi V. Application of speckle-tracking in the evaluation of carotid artery function in subjects with hypertension and diabetes. J Am Soc Echocardiogr. 2013 Aug; 26(8):901-909.e1. PMID: 23759168; PMCID: PMC3725197.
    16. Wagle KC, Rowan PJ, Poon OY, Kunik ME, Taffet GE, Braun UK. Initiation of cholinesterase inhibitors in an inpatient setting. Am J Alzheimers Dis Other Demen. 2013 Jun; 28(4):377-83. PMID: 23702586.
      View in: PubMed
    17. Reddy AK, Hartley CJ, Pham TT, Darlington G, Entman ML, Taffet GE. Young little mice express a premature cardiovascular aging phenotype. J Gerontol A Biol Sci Med Sci. 2014 Feb; 69(2):152-9. PMID: 23682160; PMCID: PMC4038241.
    18. Swan JT, Wagle KC, Thompson-Moore N, Taffet GE. Incidence of cholinesterase inhibitor therapy initiation among hospitalized patients. J Hosp Med. 2013 Jun; 8(6):304-8. PMID: 23526817.
      View in: PubMed
    19. Duerrschmid C, Crawford JR, Reineke E, Taffet GE, Trial J, Entman ML, Haudek SB. TNF receptor 1 signaling is critically involved in mediating angiotensin-II-induced cardiac fibrosis. J Mol Cell Cardiol. 2013 Apr; 57:59-67. PMID: 23337087; PMCID: PMC3593947.
    20. Cieslik KA, Trial J, Carlson S, Taffet GE, Entman ML. Aberrant differentiation of fibroblast progenitors contributes to fibrosis in the aged murine heart: role of elevated circulating insulin levels. FASEB J. 2013 Apr; 27(4):1761-71. PMID: 23303205; PMCID: PMC3606539.
    21. Reineke EL, York B, Stashi E, Chen X, Tsimelzon A, Xu J, Newgard CB, Taffet GE, Taegtmeyer H, Entman ML, O'Malley BW. SRC-2 coactivator deficiency decreases functional reserve in response to pressure overload of mouse heart. PLoS One. 2012; 7(12):e53395. PMID: 23300926; PMCID: PMC3534027.
    22. Kerfoot BP, Baker H, Pangaro L, Agarwal K, Taffet G, Mechaber AJ, Armstrong EG. An online spaced-education game to teach and assess medical students: a multi-institutional prospective trial. Acad Med. 2012 Oct; 87(10):1443-9. PMID: 22914524.
      View in: PubMed
    23. Gurha P, Abreu-Goodger C, Wang T, Ramirez MO, Drumond AL, van Dongen S, Chen Y, Bartonicek N, Enright AJ, Lee B, Kelm RJ, Reddy AK, Taffet GE, Bradley A, Wehrens XH, Entman ML, Rodriguez A. Targeted deletion of microRNA-22 promotes stress-induced cardiac dilation and contractile dysfunction. Circulation. 2012 Jun 5; 125(22):2751-61. PMID: 22570371; PMCID: PMC3503489.
    24. Mills WL, Roush RE, Moye J, Kunik ME, Wilson NL, Taffet GE, Naik AD. An educational program to assist clinicians in identifying elder investment fraud and financial exploitation. Gerontol Geriatr Educ. 2012; 33(4):351-63. PMID: 23095220.
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    25. Wagle KC, Taffet GE, Natali B. Cholinesterase inhibitor initiation in hospital setting. J Am Geriatr Soc. 2011 Oct; 59(10):1988-9. PMID: 22091527.
      View in: PubMed
    26. Lloyd EE, Crossland RF, Phillips SC, Marrelli SP, Reddy AK, Taffet GE, Hartley CJ, Bryan RM. Disruption of K(2P)6.1 produces vascular dysfunction and hypertension in mice. Hypertension. 2011 Oct; 58(4):672-8. PMID: 21876070; PMCID: PMC3205080.
    27. Sekhar RV, Patel SG, Guthikonda AP, Reid M, Balasubramanyam A, Taffet GE, Jahoor F. Deficient synthesis of glutathione underlies oxidative stress in aging and can be corrected by dietary cysteine and glycine supplementation. Am J Clin Nutr. 2011 Sep; 94(3):847-53. PMID: 21795440; PMCID: PMC3155927.
    28. Xu J, Lin SC, Chen J, Miao Y, Taffet GE, Entman ML, Wang Y. CCR2 mediates the uptake of bone marrow-derived fibroblast precursors in angiotensin II-induced cardiac fibrosis. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H538-47. PMID: 21572015; PMCID: PMC3154672.
    29. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Doppler velocity measurements from large and small arteries of mice. Am J Physiol Heart Circ Physiol. 2011 Aug; 301(2):H269-78. PMID: 21572013; PMCID: PMC3154663.
    30. Cheema FN, Abraham NS, Berger DH, Albo D, Taffet GE, Naik AD. Novel approaches to perioperative assessment and intervention may improve long-term outcomes after colorectal cancer resection in older adults. Ann Surg. 2011 May; 253(5):867-74. PMID: 21183846.
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    31. Cieslik KA, Taffet GE, Carlson S, Hermosillo J, Trial J, Entman ML. Immune-inflammatory dysregulation modulates the incidence of progressive fibrosis and diastolic stiffness in the aging heart. J Mol Cell Cardiol. 2011 Jan; 50(1):248-56. PMID: 20974150; PMCID: PMC3019252.
    32. Hartley CJ, Reddy AK, Madala S, Entman ML, Taffet GE. Feasibility of dual Doppler velocity measurements to estimate volume pulsations of an arterial segment. Ultrasound Med Biol. 2010 Jul; 36(7):1169-75. PMID: 20620703; PMCID: PMC2904320.
    33. Haudek SB, Cheng J, Du J, Wang Y, Hermosillo-Rodriguez J, Trial J, Taffet GE, Entman ML. Monocytic fibroblast precursors mediate fibrosis in angiotensin-II-induced cardiac hypertrophy. J Mol Cell Cardiol. 2010 Sep; 49(3):499-507. PMID: 20488188; PMCID: PMC2917526.
    34. Alexander NB, Taffet GE, Horne FM, Eldadah BA, Ferrucci L, Nayfield S, Studenski S. Bedside-to-Bench conference: research agenda for idiopathic fatigue and aging. J Am Geriatr Soc. 2010 May; 58(5):967-75. PMID: 20722821; PMCID: PMC4540791.
    35. Namiranian K, Lloyd EE, Crossland RF, Marrelli SP, Taffet GE, Reddy AK, Hartley CJ, Bryan RM. Cerebrovascular responses in mice deficient in the potassium channel, TREK-1. Am J Physiol Regul Integr Comp Physiol. 2010 Aug; 299(2):R461-9. PMID: 20357027; PMCID: PMC2928619.
    36. Smiechowska J, Utech A, Taffet G, Hayes T, Marcelli M, Garcia JM. Adipokines in patients with cancer anorexia and cachexia. J Investig Med. 2010 Mar; 58(3):554-9. PMID: 20215915.
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    37. Chintalgattu V, Ai D, Langley RR, Zhang J, Bankson JA, Shih TL, Reddy AK, Coombes KR, Daher IN, Pati S, Patel SS, Pocius JS, Taffet GE, Buja LM, Entman ML, Khakoo AY. Cardiomyocyte PDGFR-beta signaling is an essential component of the mouse cardiac response to load-induced stress. J Clin Invest. 2010 Feb; 120(2):472-84. PMID: 20071776; PMCID: PMC2810076.
    38. Hartley CJ, Reddy AK, Michael LH, Entman ML, Chintalagattu V, Khakoo AY, Taffet GE. Coronary flow reserve in mice: effects of age, coronary disease, and vascular loading. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:3780-3. PMID: 21096875; PMCID: PMC3341612.
    39. Reddy AK, Madala S, Jones AD, Caro WA, Eberth JF, Pham TT, Taffet GE, Hartley CJ. Multichannel pulsed Doppler signal processing for vascular measurements in mice. Ultrasound Med Biol. 2009 Dec; 35(12):2042-54. PMID: 19854566; PMCID: PMC2900799.
    40. Hyman DJ, Taffet GE. Blood pressure control in the elderly: can you have too much of a good thing? Curr Hypertens Rep. 2009 Oct; 11(5):337-42. PMID: 19737450.
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    41. Reddy AK, Namiranian K, Lloyd EE, Bryan RM, Taffet GE, Hartley CJ. Effect of isoflurane on aortic impedance in mice. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1104-5. PMID: 19964748; PMCID: PMC3341611.
    42. Hartley CJ, Reddy AK, Michael LH, Entman ML, Taffet GE. Coronary flow reserve as an index of cardiac function in mice with cardiovascular abnormalities. Conf Proc IEEE Eng Med Biol Soc. 2009; 2009:1094-7. PMID: 19963485; PMCID: PMC3341618.
    43. Bujak M, Kweon HJ, Chatila K, Li N, Taffet G, Frangogiannis NG. Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol. 2008 Apr 8; 51(14):1384-92. PMID: 18387441; PMCID: PMC3348616.
    44. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, Taffet GE. Doppler estimation of reduced coronary flow reserve in mice with pressure overload cardiac hypertrophy. Ultrasound Med Biol. 2008 Jun; 34(6):892-901. PMID: 18255218; PMCID: PMC2453594.
    45. Reddy AK, Taffet GE, Hartley CJ. Aortic impedance in Little mice. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:1397-8. PMID: 19162929; PMCID: PMC3345796.
    46. Hartley CJ, Reddy AK, Taffet GE. In-vitro evaluation of sensors and amplifiers to measure left ventricular pressure in mice. Conf Proc IEEE Eng Med Biol Soc. 2008; 2008:965-8. PMID: 19162818; PMCID: PMC3341624.
    47. Reddy AK, Amador-Noguez D, Darlington GJ, Scholz BA, Michael LH, Hartley CJ, Entman ML, Taffet GE. Cardiac function in young and old Little mice. J Gerontol A Biol Sci Med Sci. 2007 Dec; 62(12):1319-25. PMID: 18166681; PMCID: PMC2771398.
    48. Bujak M, Ren G, Kweon HJ, Dobaczewski M, Reddy A, Taffet G, Wang XF, Frangogiannis NG. Essential role of Smad3 in infarct healing and in the pathogenesis of cardiac remodeling. Circulation. 2007 Nov 6; 116(19):2127-38. PMID: 17967775.
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    49. Wang GS, Kearney DL, De Biasi M, Taffet G, Cooper TA. Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy. J Clin Invest. 2007 Oct; 117(10):2802-11. PMID: 17823658; PMCID: PMC1964514.
    50. Haudek SB, Taffet GE, Schneider MD, Mann DL. TNF provokes cardiomyocyte apoptosis and cardiac remodeling through activation of multiple cell death pathways. J Clin Invest. 2007 Sep; 117(9):2692-701. PMID: 17694177; PMCID: PMC1937497.
    51. Duran JR, Taffet G. Coronary microvascular dysfunction. N Engl J Med. 2007 May 31; 356(22):2324-5; author reply 2325. PMID: 17538094.
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    52. Hartley CJ, Reddy AK, Madala S, Michael LH, Entman ML, Taffet GE. Effects of isoflurane on coronary blood flow velocity in young, old and ApoE(-/-) mice measured by Doppler ultrasound. Ultrasound Med Biol. 2007 Apr; 33(4):512-21. PMID: 17346873; PMCID: PMC2048667.
    53. Frangogiannis NG, Dewald O, Xia Y, Ren G, Haudek S, Leucker T, Kraemer D, Taffet G, Rollins BJ, Entman ML. Critical role of monocyte chemoattractant protein-1/CC chemokine ligand 2 in the pathogenesis of ischemic cardiomyopathy. Circulation. 2007 Feb 6; 115(5):584-92. PMID: 17283277.
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    54. Sano M, Izumi Y, Helenius K, Asakura M, Rossi DJ, Xie M, Taffet G, Hu L, Pautler RG, Wilson CR, Boudina S, Abel ED, Taegtmeyer H, Scaglia F, Graham BH, Kralli A, Shimizu N, Tanaka H, Mäkelä TP, Schneider MD. Ménage-à-trois 1 is critical for the transcriptional function of PPARgamma coactivator 1. Cell Metab. 2007 Feb; 5(2):129-42. PMID: 17276355.
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    55. Zymek P, Nah DY, Bujak M, Ren G, Koerting A, Leucker T, Huebener P, Taffet G, Entman M, Frangogiannis NG. Interleukin-10 is not a critical regulator of infarct healing and left ventricular remodeling. Cardiovasc Res. 2007 May 1; 74(2):313-22. PMID: 17188669; PMCID: PMC1924681.
    56. Xie M, Zhang D, Dyck JR, Li Y, Zhang H, Morishima M, Mann DL, Taffet GE, Baldini A, Khoury DS, Schneider MD. A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci U S A. 2006 Nov 14; 103(46):17378-83. PMID: 17085580; PMCID: PMC1859937.
    57. Kannankeril PJ, Mitchell BM, Goonasekera SA, Chelu MG, Zhang W, Sood S, Kearney DL, Danila CI, De Biasi M, Wehrens XH, Pautler RG, Roden DM, Taffet GE, Dirksen RT, Anderson ME, Hamilton SL. Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy. Proc Natl Acad Sci U S A. 2006 Aug 8; 103(32):12179-84. PMID: 16873551; PMCID: PMC1567715.
    58. Thakker GD, Frangogiannis NG, Bujak M, Zymek P, Gaubatz JW, Reddy AK, Taffet G, Michael LH, Entman ML, Ballantyne CM. Effects of diet-induced obesity on inflammation and remodeling after myocardial infarction. Am J Physiol Heart Circ Physiol. 2006 Nov; 291(5):H2504-14. PMID: 16731644.
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    59. Zhang YM, Bo J, Taffet GE, Chang J, Shi J, Reddy AK, Michael LH, Schneider MD, Entman ML, Schwartz RJ, Wei L. Targeted deletion of ROCK1 protects the heart against pressure overload by inhibiting reactive fibrosis. FASEB J. 2006 May; 20(7):916-25. PMID: 16675849.
      View in: PubMed
    60. Reddy AK, Taffet GE, Li YH, Lim SW, Pham TT, Pocius JS, Entman ML, Michael LH, Hartley CJ. Pulsed Doppler signal processing for use in mice: applications. IEEE Trans Biomed Eng. 2005 Oct; 52(10):1771-83. PMID: 16235663.
      View in: PubMed
    61. Schillinger KJ, Tsai SY, Taffet GE, Reddy AK, Marian AJ, Entman ML, Oka K, Chan L, O'Malley BW. Regulatable atrial natriuretic peptide gene therapy for hypertension. Proc Natl Acad Sci U S A. 2005 Sep 27; 102(39):13789-94. PMID: 16162668; PMCID: PMC1236585.
    62. Ladd AN, Taffet G, Hartley C, Kearney DL, Cooper TA. Cardiac tissue-specific repression of CELF activity disrupts alternative splicing and causes cardiomyopathy. Mol Cell Biol. 2005 Jul; 25(14):6267-78. PMID: 15988035; PMCID: PMC1168813.
    63. Garcia JM, Garcia-Touza M, Hijazi RA, Taffet G, Epner D, Mann D, Smith RG, Cunningham GR, Marcelli M. Active ghrelin levels and active to total ghrelin ratio in cancer-induced cachexia. J Clin Endocrinol Metab. 2005 May; 90(5):2920-6. PMID: 15713718.
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    64. Sidhu JS, Rajawat YS, Rami TG, Gollob MH, Wang Z, Yuan R, Marian AJ, DeMayo FJ, Weilbacher D, Taffet GE, Davies JK, Carling D, Khoury DS, Roberts R. Transgenic mouse model of ventricular preexcitation and atrioventricular reentrant tachycardia induced by an AMP-activated protein kinase loss-of-function mutation responsible for Wolff-Parkinson-White syndrome. Circulation. 2005 Jan 4; 111(1):21-9. PMID: 15611370; PMCID: PMC2908313.
    65. Dewald O, Frangogiannis NG, Zoerlein MP, Duerr GD, Taffet G, Michael LH, Welz A, Entman ML. A murine model of ischemic cardiomyopathy induced by repetitive ischemia and reperfusion. Thorac Cardiovasc Surg. 2004 Oct; 52(5):305-11. PMID: 15470614.
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    66. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Noninvasive ultrasonic measurement of arterial wall motion in mice. Am J Physiol Heart Circ Physiol. 2004 Sep; 287(3):H1426-32. PMID: 15317682.
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    67. Sano M, Wang SC, Shirai M, Scaglia F, Xie M, Sakai S, Tanaka T, Kulkarni PA, Barger PM, Youker KA, Taffet GE, Hamamori Y, Michael LH, Craigen WJ, Schneider MD. Activation of cardiac Cdk9 represses PGC-1 and confers a predisposition to heart failure. EMBO J. 2004 Sep 1; 23(17):3559-69. PMID: 15297879; PMCID: PMC516624.
    68. Appleton GO, Li Y, Taffet GE, Hartley CJ, Michael LH, Entman ML, Roberts R, Khoury DS. Determinants of cardiac electrophysiological properties in mice. J Interv Card Electrophysiol. 2004 Aug; 11(1):5-14. PMID: 15273447.
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    69. Wei L, Taffet GE, Khoury DS, Bo J, Li Y, Yatani A, Delaughter MC, Klevitsky R, Hewett TE, Robbins J, Michael LH, Schneider MD, Entman ML, Schwartz RJ. Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. FASEB J. 2004 May; 18(7):857-9. PMID: 15033930.
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    70. Weisleder N, Taffet GE, Capetanaki Y. Bcl-2 overexpression corrects mitochondrial defects and ameliorates inherited desmin null cardiomyopathy. Proc Natl Acad Sci U S A. 2004 Jan 20; 101(3):769-74. PMID: 14715896; PMCID: PMC321756.
    71. Hartley CJ, Reddy AK, Madala S, Entman ML, Michael LH, Taffet GE. Noninvasive ultrasonic measurement of arterial wall motion in mice. Conf Proc IEEE Eng Med Biol Soc. 2004; 5:3688-91. PMID: 17271094.
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    72. Li YH, Reddy AK, Ochoa LN, Pham TT, Hartley CJ, Michael LH, Entman ML, Taffet GE. Effect of age on peripheral vascular response to transverse aortic banding in mice. J Gerontol A Biol Sci Med Sci. 2003 Oct; 58(10):B895-9. PMID: 14570855.
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    73. Li YH, Reddy AK, Taffet GE, Michael LH, Entman ML, Hartley CJ. Doppler evaluation of peripheral vascular adaptations to transverse aortic banding in mice. Ultrasound Med Biol. 2003 Sep; 29(9):1281-9. PMID: 14553805.
      View in: PubMed
    74. Reddy AK, Li YH, Pham TT, Ochoa LN, Trevino MT, Hartley CJ, Michael LH, Entman ML, Taffet GE. Measurement of aortic input impedance in mice: effects of age on aortic stiffness. Am J Physiol Heart Circ Physiol. 2003 Oct; 285(4):H1464-70. PMID: 12775560.
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    75. Oh H, Wang SC, Prahash A, Sano M, Moravec CS, Taffet GE, Michael LH, Youker KA, Entman ML, Schneider MD. Telomere attrition and Chk2 activation in human heart failure. Proc Natl Acad Sci U S A. 2003 Apr 29; 100(9):5378-83. PMID: 12702777; PMCID: PMC154353.
    76. Reddy AK, Taffet GE, Madala S, Michael LH, Entman ML, Hartley CJ. Noninvasive blood pressure measurement in mice using pulsed Doppler ultrasound. Ultrasound Med Biol. 2003 Mar; 29(3):379-85. PMID: 12706189.
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    77. Dewald O, Frangogiannis NG, Zoerlein M, Duerr GD, Klemm C, Knuefermann P, Taffet G, Michael LH, Crapo JD, Welz A, Entman ML. Development of murine ischemic cardiomyopathy is associated with a transient inflammatory reaction and depends on reactive oxygen species. Proc Natl Acad Sci U S A. 2003 Mar 4; 100(5):2700-5. PMID: 12586861; PMCID: PMC151404.
    78. Baumgarten G, Knuefermann P, Kalra D, Gao F, Taffet GE, Michael L, Blackshear PJ, Carballo E, Sivasubramanian N, Mann DL. Load-dependent and -independent regulation of proinflammatory cytokine and cytokine receptor gene expression in the adult mammalian heart. Circulation. 2002 May 7; 105(18):2192-7. PMID: 11994254.
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    79. Minamino T, Yujiri T, Terada N, Taffet GE, Michael LH, Johnson GL, Schneider MD. MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq. Proc Natl Acad Sci U S A. 2002 Mar 19; 99(6):3866-71. PMID: 11891332; PMCID: PMC122615.
    80. Gould KE, Taffet GE, Michael LH, Christie RM, Konkol DL, Pocius JS, Zachariah JP, Chaupin DF, Daniel SL, Sandusky GE, Hartley CJ, Entman ML. Heart failure and greater infarct expansion in middle-aged mice: a relevant model for postinfarction failure. Am J Physiol Heart Circ Physiol. 2002 Feb; 282(2):H615-21. PMID: 11788410.
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    81. Hartley CJ, Taffet GE, Reddy AK, Entman ML, Michael LH. Noninvasive cardiovascular phenotyping in mice. ILAR J. 2002; 43(3):147-58. PMID: 12105382.
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    82. Oh H, Taffet GE, Youker KA, Entman ML, Overbeek PA, Michael LH, Schneider MD. Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival. Proc Natl Acad Sci U S A. 2001 Aug 28; 98(18):10308-13. PMID: 11517337; PMCID: PMC56957.
    83. Schildmeyer LA, Braun R, Taffet G, Debiasi M, Burns AE, Bradley A, Schwartz RJ. Impaired vascular contractility and blood pressure homeostasis in the smooth muscle alpha-actin null mouse. FASEB J. 2000 Nov; 14(14):2213-20. PMID: 11053242.
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    84. Kurrelmeyer KM, Michael LH, Baumgarten G, Taffet GE, Peschon JJ, Sivasubramanian N, Entman ML, Mann DL. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci U S A. 2000 May 9; 97(10):5456-61. PMID: 10779546; PMCID: PMC25850.
    85. Zhang D, Gaussin V, Taffet GE, Belaguli NS, Yamada M, Schwartz RJ, Michael LH, Overbeek PA, Schneider MD. TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. Nat Med. 2000 May; 6(5):556-63. PMID: 10802712.
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    86. Nossuli TO, Lakshminarayanan V, Baumgarten G, Taffet GE, Ballantyne CM, Michael LH, Entman ML. A chronic mouse model of myocardial ischemia-reperfusion: essential in cytokine studies. Am J Physiol Heart Circ Physiol. 2000 Apr; 278(4):H1049-55. PMID: 10749697.
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    87. Delaughter MC, Taffet GE, Fiorotto ML, Entman ML, Schwartz RJ. Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice. FASEB J. 1999 Nov; 13(14):1923-9. PMID: 10544175.
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    88. Milner DJ, Taffet GE, Wang X, Pham T, Tamura T, Hartley C, Gerdes AM, Capetanaki Y. The absence of desmin leads to cardiomyocyte hypertrophy and cardiac dilation with compromised systolic function. J Mol Cell Cardiol. 1999 Nov; 31(11):2063-76. PMID: 10591032.
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    89. Michael LH, Ballantyne CM, Zachariah JP, Gould KE, Pocius JS, Taffet GE, Hartley CJ, Pham TT, Daniel SL, Funk E, Entman ML. Myocardial infarction and remodeling in mice: effect of reperfusion. Am J Physiol. 1999 Aug; 277(2 Pt 2):H660-8. PMID: 10444492.
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    90. Hartley CJ, Lacy JL, Dai D, Nayak N, Taffet GE, Entman ML, Michael LH. Functional cardiac imaging in mice using Ta-178. Nat Med. 1999 Feb; 5(2):237-9. PMID: 9930875.
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    91. Bick RJ, Van Winkle WB, Taffet GE. Cardiac sarcoplasmic reticulum membrane lipid asymmetries. Ann N Y Acad Sci. 1998 Sep 16; 853:365-7. PMID: 10603981.
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    92. Bick RJ, Buja LM, Van Winkle WB, Taffet GE. Membrane asymmetry in isolated canine cardiac sarcoplasmic reticulum: comparison with skeletal muscle sarcoplasmic reticulum. J Membr Biol. 1998 Jul 15; 164(2):169-75. PMID: 9662560.
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    93. Taffet GE, Pham TT, Hartley CJ. The age-associated alterations in late diastolic function in mice are improved by caloric restriction. J Gerontol A Biol Sci Med Sci. 1997 Nov; 52(6):B285-90. PMID: 9402929.
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    94. Kapadia SR, Oral H, Lee J, Nakano M, Taffet GE, Mann DL. Hemodynamic regulation of tumor necrosis factor-alpha gene and protein expression in adult feline myocardium. Circ Res. 1997 Aug; 81(2):187-95. PMID: 9242179.
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    95. Guerra-Garcia H, Taffet G, Protas EJ. Considerations related to disability and exercise in elderly women with congestive heart failure. J Cardiovasc Nurs. 1997 Jul; 11(4):60-74. PMID: 9200020.
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    96. Hartley CJ, Taffet GE, Michael LH, Pham TT, Entman ML. Noninvasive determination of pulse-wave velocity in mice. Am J Physiol. 1997 Jul; 273(1 Pt 2):H494-500. PMID: 9249523.
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    97. Taffet GE, Michael LA, Tate CA. Exercise training improves lusitropy by isoproterenol in papillary muscles from aged rats. J Appl Physiol (1985). 1996 Oct; 81(4):1488-94. PMID: 8904558.
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    98. Tate CA, Helgason T, Hyek MF, McBride RP, Chen M, Richardson MA, Taffet GE. SERCA2a and mitochondrial cytochrome oxidase expression are increased in hearts of exercise-trained old rats. Am J Physiol. 1996 Jul; 271(1 Pt 2):H68-72. PMID: 8760159.
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    99. Taffet GE, Hartley CJ, Wen X, Pham T, Michael LH, Entman ML. Noninvasive indexes of cardiac systolic and diastolic function in hyperthyroid and senescent mouse. Am J Physiol. 1996 Jun; 270(6 Pt 2):H2204-9. PMID: 8764275.
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    100. Beer RJ, Teasdale TA, Ghusn HF, Taffet GE. Estimation of severity of illness with APACHE II: age-related implications in cardiac arrest outcomes. Resuscitation. 1994 May; 27(3):189-95. PMID: 8079052.
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    101. Tate CA, Hyek MF, Taffet GE. Mechanisms for the responses of cardiac muscle to physical activity in old age. Med Sci Sports Exerc. 1994 May; 26(5):561-7. PMID: 8007803.
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    102. McMillin JB, Taffet GE, Taegtmeyer H, Hudson EK, Tate CA. Mitochondrial metabolism and substrate competition in the aging Fischer rat heart. Cardiovasc Res. 1993 Dec; 27(12):2222-8. PMID: 8313432.
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    103. Tate C, Hamra M, Shin G, Taffet G, McBride P, Entman M. Canine cardiac sarcoplasmic reticulum is not altered with endurance exercise training. Med Sci Sports Exerc. 1993 Nov; 25(11):1246-57. PMID: 8289611.
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    104. Taffet GE, Tate CA. CaATPase content is lower in cardiac sarcoplasmic reticulum isolated from old rats. Am J Physiol. 1993 May; 264(5 Pt 2):H1609-14. PMID: 8498573.
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    105. Taffet GE, Pham TT, Bick DL, Entman ML, Pownall HJ, Bick RJ. The calcium uptake of the rat heart sarcoplasmic reticulum is altered by dietary lipid. J Membr Biol. 1993 Jan; 131(1):35-42. PMID: 8381872.
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    106. Taffet GE, Tate CA. The MgATPase activity of rat cardiac sarcoplasmic reticulum is a function of the calcium ATPase protein. Arch Biochem Biophys. 1992 Dec; 299(2):287-94. PMID: 1444468.
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    107. Taffet GE, Teasdale TA, Bleyer AJ, Kutka NJ, Luchi RJ. Survival of elderly men with congestive heart failure. Age Ageing. 1992 Jan; 21(1):49-55. PMID: 1553860.
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    108. Tate CA, Hyek MF, Taffet GE. The role of calcium in the energetics of contracting skeletal muscle. Sports Med. 1991 Sep; 12(3):208-17. PMID: 1664541.
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    109. Tate CA, Shin G, Walseth TF, Taffet GE, Bick RJ, Entman ML. Nucleotide specificity of cardiac sarcoplasmic reticulum. Inhibition of GTPase activity by ATP analogue in fluorescein isothiocyanate-modified calcium ATPase. J Biol Chem. 1991 Aug 25; 266(24):16165-70. PMID: 1831455.
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    110. Luchi RJ, Taffet GE, Teasdale TA. Congestive heart failure in the elderly. J Am Geriatr Soc. 1991 Aug; 39(8):810-25. PMID: 2071813.
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    111. Schonwetter RS, Teasdale TA, Taffet G, Robinson BE, Luchi RJ. Educating the elderly: cardiopulmonary resuscitation decisions before and after intervention. J Am Geriatr Soc. 1991 Apr; 39(4):372-7. PMID: 2010586.
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    112. Tate CA, Taffet GE, Hudson EK, Blaylock SL, McBride RP, Michael LH. Enhanced calcium uptake of cardiac sarcoplasmic reticulum in exercise-trained old rats. Am J Physiol. 1990 Feb; 258(2 Pt 2):H431-5. PMID: 2137986.
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    113. Tate CA, Taffet GE. The regulatory role of calcium in striated muscle. Med Sci Sports Exerc. 1989 Aug; 21(4):393-8. PMID: 2674591.
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    114. Taffet GE, Teasdale TA, Luchi RJ. In-hospital cardiopulmonary resuscitation. JAMA. 1988 Oct 14; 260(14):2069-72. PMID: 3270334.
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    115. Teasdale TA, Taffet GE, Luchi RJ, Adam E. Urinary incontinence in a community-residing elderly population. J Am Geriatr Soc. 1988 Jul; 36(7):600-6. PMID: 3385112.
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    116. Brown DL, Musher DM, Taffet GE. Hematogenously acquired Aspergillus vertebral osteomyelitis in seemingly immunocompetent drug addicts. West J Med. 1987 Jul; 147(1):84-5. PMID: 3321709; PMCID: PMC1025835.
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