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PAUL KLOTMAN

TitlePresident
InstitutionBaylor College of Medicine
DepartmentOffice of the President
AddressOne Baylor Plaza, BCM 102
Houston TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Nephrology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Cheung JY, Gordon J, Wang J, Song J, Zhang XQ, Tilley DG, Gao E, Koch WJ, Rabinowitz J, Klotman PE, Khalili K, Feldman AM. Cardiac Dysfunction in HIV-1 Transgenic Mouse: Role of Stress and BAG3. Clin Transl Sci. 2015 Aug; 8(4):305-10. PMID: 26300236.
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    2. Razzak Chaudhary S, Workeneh BT, Montez-Rath ME, Zolopa AR, Klotman PE, Winkelmayer WC. Trends in the outcomes of end-stage renal disease secondary to human immunodeficiency virus-associated nephropathy. Nephrol Dial Transplant. 2015 Oct; 30(10):1734-40. PMID: 26175146.
      View in: PubMed
    3. Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE. Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte. PLoS One. 2014; 9(6):e100660. PMID: 24949636; PMCID: PMC4065073.
    4. Potla U, Ni J, Vadaparampil J, Yang G, Leventhal JS, Campbell KN, Chuang PY, Morozov A, He JC, D'Agati VD, Klotman PE, Kaufman L. Podocyte-specific RAP1GAP expression contributes to focal segmental glomerulosclerosis-associated glomerular injury. J Clin Invest. 2014 Apr; 124(4):1757-69. PMID: 24642466; PMCID: PMC3973092.
    5. Hutter R, Huang L, Speidl WS, Giannarelli C, Trubin P, Bauriedel G, Klotman ME, Fuster V, Badimon JJ, Klotman PE. Novel small leucine-rich repeat protein podocan is a negative regulator of migration and proliferation of smooth muscle cells, modulates neointima formation, and is expressed in human atheroma. Circulation. 2013 Nov 26; 128(22):2351-63. PMID: 24043300; PMCID: PMC3917564.
    6. Wyatt CM, Schwartz GJ, Owino Ong'or W, Abuya J, Abraham AG, Mboku C, M'mene LB, Koima WJ, Hotta M, Maier P, Klotman PE, Wools-Kaloustian K. Estimating kidney function in HIV-infected adults in Kenya: comparison to a direct measure of glomerular filtration rate by iohexol clearance. PLoS One. 2013; 8(8):e69601. PMID: 23950899; PMCID: PMC3738577.
    7. Gu L, Dai Y, Xu J, Mallipattu S, Kaufman L, Klotman PE, He JC, Chuang PY. Deletion of podocyte STAT3 mitigates the entire spectrum of HIV-1-associated nephropathy. AIDS. 2013 Apr 24; 27(7):1091-8. PMID: 23343908; PMCID: PMC3918880.
    8. Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma'ayan A, He JC. Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase. J Am Soc Nephrol. 2013 Apr; 24(5):801-11. PMID: 23559582; PMCID: PMC3636790.
    9. Sharma M, Magenheimer LK, Home T, Tamano KN, Singhal PC, Hyink DP, Klotman PE, Vanden Heuvel GB, Fields TA. Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy. Am J Physiol Renal Physiol. 2013 Apr 15; 304(8):F1127-36. PMID: 23389453; PMCID: PMC3625839.
    10. Mallipattu SK, Liu R, Zhong Y, Chen EY, D'Agati V, Kaufman L, Ma'ayan A, Klotman PE, Chuang PY, He JC. Expression of HIV transgene aggravates kidney injury in diabetic mice. Kidney Int. 2013 Apr; 83(4):626-34. PMID: 23325078; PMCID: PMC3612382.
    11. Lipkowitz MS, Freedman BI, Langefeld CD, Comeau ME, Bowden DW, Kao WH, Astor BC, Bottinger EP, Iyengar SK, Klotman PE, Freedman RG, Zhang W, Parekh RS, Choi MJ, Nelson GW, Winkler CA, Kopp JB. Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans. Kidney Int. 2013 Jan; 83(1):114-20. PMID: 22832513; PMCID: PMC3484228.
    12. Hays T, D'Agati VD, Garellek JA, Warren T, Trubin ME, Hyink DP, He JC, Klotman PE. Glomerular MYH9 expression is reduced by HIV-1. AIDS. 2012 Apr 24; 26(7):797-803. PMID: 22313957; PMCID: PMC3913730.
    13. Mallipattu SK, Liu R, Zheng F, Narla G, Ma'ayan A, Dikman S, Jain MK, Saleem M, D'Agati V, Klotman P, Chuang PY, He JC. Kruppel-like factor 15 (KLF15) is a key regulator of podocyte differentiation. J Biol Chem. 2012 Jun 1; 287(23):19122-35. PMID: 22493483; PMCID: PMC3365945.
    14. Zhong Y, Wu Y, Liu R, Deng Y, Mallipattu SK, Klotman PE, Chuang PY, He JC. Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure. Kidney Int. 2012 May; 81(9):856-64. PMID: 22258322; PMCID: PMC3326224.
    15. Papeta N, Kiryluk K, Patel A, Sterken R, Kacak N, Snyder HJ, Imus PH, Mhatre AN, Lawani AK, Julian BA, Wyatt RJ, Novak J, Wyatt CM, Ross MJ, Winston JA, Klotman ME, Cohen DJ, Appel GB, D'Agati VD, Klotman PE, Gharavi AG. APOL1 variants increase risk for FSGS and HIVAN but not IgA nephropathy. J Am Soc Nephrol. 2011 Nov; 22(11):1991-6. PMID: 21997397; PMCID: PMC3231781.
    16. Wyatt CM, Meliambro K, Klotman PE. Recent progress in HIV-associated nephropathy. Annu Rev Med. 2012; 63:147-59. PMID: 21888512.
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    17. Shea JA, Stern DT, Klotman PE, Clayton CP, O'Hara JL, Feldman MD, Griendling KK, Moss M, Straus SE, Jagsi R. Career development of physician scientists: a survey of leaders in academic medicine. Am J Med. 2011 Aug; 124(8):779-87. PMID: 21640329.
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    18. Medapalli RK, He JC, Klotman PE. HIV-associated nephropathy: pathogenesis. Curr Opin Nephrol Hypertens. 2011 May; 20(3):306-11. PMID: 21358326; PMCID: PMC3153858.
    19. Stern DT, Podolsky AH, Klotman P. Follow the leader. Educ Health (Abingdon). 2011 Apr; 24(1):615. PMID: 21710426.
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    20. Hostetter TH, Kochis DJ, Shaffer RN, Chertow G, Harmon WE, Klotman PE, Powe NR, Sedor JR, Smedberg PC, Watnick S, Winkelmayer WC. World Kidney Day 2011. J Am Soc Nephrol. 2011 Mar; 22(3):397-8. PMID: 21355055.
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    21. Chen P, Chen BK, Mosoian A, Hays T, Ross MJ, Klotman PE, Klotman ME. Virological synapses allow HIV-1 uptake and gene expression in renal tubular epithelial cells. J Am Soc Nephrol. 2011 Mar; 22(3):496-507. PMID: 21335514; PMCID: PMC3060443.
    22. Wyatt CM, Hoover DR, Shi Q, Tien PC, Karim R, Cohen MH, Goderre JL, Seaberg EC, Lazar J, Young MA, Klotman PE, Anastos K. Pre-existing albuminuria predicts AIDS and non-AIDS mortality in women initiating antiretroviral therapy. Antivir Ther. 2011; 16(4):591-6. PMID: 21685547; PMCID: PMC3119869.
    23. Ratnam KK, Feng X, Chuang PY, Verma V, Lu TC, Wang J, Jin Y, Farias EF, Napoli JL, Chen N, Kaufman L, Takano T, D'Agati VD, Klotman PE, He JC. Role of the retinoic acid receptor-? in HIV-associated nephropathy. Kidney Int. 2011 Mar; 79(6):624-34. PMID: 21150871; PMCID: PMC3050085.
    24. Wyatt CM, Hoover DR, Shi Q, Seaberg E, Wei C, Tien PC, Karim R, Lazar J, Young MA, Cohen MH, Klotman PE, Anastos K. Microalbuminuria is associated with all-cause and AIDS mortality in women with HIV infection. J Acquir Immune Defic Syndr. 2010 Sep; 55(1):73-7. PMID: 20098331; PMCID: PMC2888617.
    25. Bishop TF, Klotman PE, Vladeck BC, Callahan MA. The future of malpractice reform. Am J Med. 2010 Aug; 123(8):673-4. PMID: 20670716.
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    26. Kaufman L, Potla U, Coleman S, Dikiy S, Hata Y, Kurihara H, He JC, D'Agati VD, Klotman PE. Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis. J Biol Chem. 2010 Aug 13; 285(33):25677-85. PMID: 20562105; PMCID: PMC2919131.
    27. Mosoian A, Teixeira A, Burns CS, Sander LE, Gusella GL, He C, Blander JM, Klotman P, Klotman ME. Prothymosin-alpha inhibits HIV-1 via Toll-like receptor 4-mediated type I interferon induction. Proc Natl Acad Sci U S A. 2010 Jun 1; 107(22):10178-83. PMID: 20479248; PMCID: PMC2890444.
    28. Snyder A, Alsauskas ZC, Leventhal JS, Rosenstiel PE, Gong P, Chan JJ, Barley K, He JC, Klotman ME, Ross MJ, Klotman PE. HIV-1 viral protein r induces ERK and caspase-8-dependent apoptosis in renal tubular epithelial cells. AIDS. 2010 May 15; 24(8):1107-19. PMID: 20404718; PMCID: PMC2860650.
    29. Villarroya J, Diaz-Delfin J, Hyink D, Domingo P, Giralt M, Klotman PE, Villarroya F. HIV type-1 transgene expression in mice alters adipose tissue and adipokine levels: towards a rodent model of HIV type-1 lipodystrophy. Antivir Ther. 2010; 15(7):1021-8. PMID: 21041917.
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    30. Kaufman L, Collins SE, Klotman PE. The pathogenesis of HIV-associated nephropathy. Adv Chronic Kidney Dis. 2010 Jan; 17(1):36-43. PMID: 20005487.
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    31. Rosenstiel PE, Chan J, Snyder A, Planelles V, D'Agati VD, Klotman PE, Klotman ME. HIV-1 Vpr activates the DNA damage response in renal tubule epithelial cells. AIDS. 2009 Sep 24; 23(15):2054-6. PMID: 19657269; PMCID: PMC3982604.
    32. Snyder A, Alsauskas Z, Gong P, Rosenstiel PE, Klotman ME, Klotman PE, Ross MJ. FAT10: a novel mediator of Vpr-induced apoptosis in human immunodeficiency virus-associated nephropathy. J Virol. 2009 Nov; 83(22):11983-8. PMID: 19726511; PMCID: PMC2772664.
    33. Paragas N, Nickolas TL, Wyatt C, Forster CS, Sise M, Morgello S, Jagla B, Buchen C, Stella P, Sanna-Cherchi S, Carnevali ML, Mattei S, Bovino A, Argentiero L, Magnano A, Devarajan P, Schmidt-Ott KM, Allegri L, Klotman P, D'Agati V, Gharavi AG, Barasch J. Urinary NGAL marks cystic disease in HIV-associated nephropathy. J Am Soc Nephrol. 2009 Aug; 20(8):1687-92. PMID: 19628667; PMCID: PMC2723987.
    34. Feng X, Lu TC, Chuang PY, Fang W, Ratnam K, Xiong H, Ouyang X, Shen Y, Levy DE, Hyink D, Klotman M, D'Agati V, Iyengar R, Klotman PE, He JC. Reduction of Stat3 activity attenuates HIV-induced kidney injury. J Am Soc Nephrol. 2009 Oct; 20(10):2138-46. PMID: 19608706; PMCID: PMC2754106.
    35. Rosenstiel P, Gharavi A, D'Agati V, Klotman P. Transgenic and infectious animal models of HIV-associated nephropathy. J Am Soc Nephrol. 2009 Nov; 20(11):2296-304. PMID: 19497967.
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    36. Papeta N, Chan KT, Prakash S, Martino J, Kiryluk K, Ballard D, Bruggeman LA, Frankel R, Zheng Z, Klotman PE, Zhao H, D'Agati VD, Lifton RP, Gharavi AG. Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression. J Clin Invest. 2009 May; 119(5):1178-88. PMID: 19381020; PMCID: PMC2673856.
    37. DuBose TD, Behrens MT, Berns A, Davis C, Goldfarb S, Hostetter T, Klotman P, Linas S, Owens S, Szczech L, Himmelfarb J. The patient-centered medical home and nephrology. J Am Soc Nephrol. 2009 Apr; 20(4):681-2. PMID: 19297553.
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    38. Szczech LA, Harmon W, Hostetter TH, Klotman PE, Powe NR, Sedor JR, Smedberg P, Himmelfarb J. World Kidney Day 2009: problems and challenges in the emerging epidemic of kidney disease. J Am Soc Nephrol. 2009 Mar; 20(3):453-5. PMID: 19244576.
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    39. Abbadessa G, Accolla R, Aiuti F, Albini A, Aldovini A, Alfano M, Antonelli G, Bartholomew C, Bentwich Z, Bertazzoni U, Berzofsky JA, Biberfeld P, Boeri E, Buonaguro L, Buonaguro FM, Bukrinsky M, Burny A, Caruso A, Cassol S, Chandra P, Ceccherini-Nelli L, Chieco-Bianchi L, Clerici M, Colombini-Hatch S, de Giuli Morghen C, de Maria A, de Rossi A, Dierich M, Della-Favera R, Dolei A, Douek D, Erfle V, Felber B, Fiorentini S, Franchini G, Gershoni JM, Gotch F, Green P, Greene WC, Hall W, Haseltine W, Jacobson S, Kallings LO, Kalyanaraman VS, Katinger H, Khalili K, Klein G, Klein E, Klotman M, Klotman P, Kotler M, Kurth R, Lafeuillade A, La Placa M, Lewis J, Lillo F, Lisziewicz J, Lomonico A, Lopalco L, Lori F, Lusso P, Macchi B, Malim M, Margolis L, Markham PD, McClure M, Miller N, Mingari MC, Moretta L, Noonan D, O'Brien S, Okamoto T, Pal R, Palese P, Panet A, Pantaleo G, Pavlakis G, Pistello M, Plotkin S, Poli G, Pomerantz R, Radaelli A, Robertguroff M, Roederer M, Sarngadharan MG, Schols D, Secchiero P, Shearer G, Siccardi A, Stevenson M, Svoboda J, Tartaglia J, Torelli G, Tornesello ML, Tschachler E, Vaccarezza M, Vallbracht A, van Lunzen J, Varnier O, Vicenzi E, von Melchner H, Witz I, Zagury D, Zagury JF, Zauli G, Zipeto D. Unsung hero Robert C. Gallo. Science. 2009 Jan 9; 323(5911):206-7. PMID: 19131607.
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    40. Chan KT, Papeta N, Martino J, Zheng Z, Frankel RZ, Klotman PE, D'Agati VD, Lifton RP, Gharavi AG. Accelerated development of collapsing glomerulopathy in mice congenic for the HIVAN1 locus. Kidney Int. 2009 Feb; 75(4):366-72. PMID: 19092797; PMCID: PMC2753461.
    41. Wyatt CM, Morgello S, Katz-Malamed R, Wei C, Klotman ME, Klotman PE, D'Agati VD. The spectrum of kidney disease in patients with AIDS in the era of antiretroviral therapy. Kidney Int. 2009 Feb; 75(4):428-34. PMID: 19052538; PMCID: PMC2704860.
    42. Hanss B, Leal-Pinto E, Teixeira A, Tran B, Lee CH, Henderson SC, Klotman PE. Localization of the nucleic acid channel regulatory subunit, cytosolic malate dehydrogenase. J Membr Biol. 2008 Nov-Dec; 226(1-3):1-8. PMID: 19015805.
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    43. Wyatt CM, Klotman PE. Kidney disease in HIV infection: introduction. Semin Nephrol. 2008 Nov; 28(6):511-2. PMID: 19013321; PMCID: PMC2640835.
    44. Wyatt CM, Klotman PE, D'Agati VD. HIV-associated nephropathy: clinical presentation, pathology, and epidemiology in the era of antiretroviral therapy. Semin Nephrol. 2008 Nov; 28(6):513-22. PMID: 19013322; PMCID: PMC2656916.
    45. Ratnam KK, He CJ, Klotman P. Nef as a Proliferative Factor for Kidney Epithelial Cells in HIV-Associated Nephropathy. Clin Med Oncol. 2008; 2:539-45. PMID: 21892329; PMCID: PMC3161694.
    46. Wyatt CM, Malvestutto C, Coca SG, Klotman PE, Parikh CR. The impact of hepatitis C virus coinfection on HIV-related kidney disease: a systematic review and meta-analysis. AIDS. 2008 Sep 12; 22(14):1799-807. PMID: 18753863; PMCID: PMC2733170.
    47. Lu TC, Wang Z, Feng X, Chuang P, Fang W, Chen Y, Neves S, Maayan A, Xiong H, Liu Y, Iyengar R, Klotman PE, He JC. Retinoic acid utilizes CREB and USF1 in a transcriptional feed-forward loop in order to stimulate MKP1 expression in human immunodeficiency virus-infected podocytes. Mol Cell Biol. 2008 Sep; 28(18):5785-94. PMID: 18625721; PMCID: PMC2546933.
    48. Rosenstiel PE, Gruosso T, Letourneau AM, Chan JJ, LeBlanc A, Husain M, Najfeld V, Planelles V, D'Agati VD, Klotman ME, Klotman PE. HIV-1 Vpr inhibits cytokinesis in human proximal tubule cells. Kidney Int. 2008 Oct; 74(8):1049-58. PMID: 18614999; PMCID: PMC4039560.
    49. Korgaonkar SN, Feng X, Ross MD, Lu TC, D'Agati V, Iyengar R, Klotman PE, He JC. HIV-1 upregulates VEGF in podocytes. J Am Soc Nephrol. 2008 May; 19(5):877-83. PMID: 18443354; PMCID: PMC2386717.
    50. Sarpel U, Vladeck BC, Divino CM, Klotman PE. Fact and fiction: debunking myths in the US healthcare system. Ann Surg. 2008 Apr; 247(4):563-9. PMID: 18362617.
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    51. Lu TC, He JC, Wang ZH, Feng X, Fukumi-Tominaga T, Chen N, Xu J, Iyengar R, Klotman PE. HIV-1 Nef disrupts the podocyte actin cytoskeleton by interacting with diaphanous interacting protein. J Biol Chem. 2008 Mar 28; 283(13):8173-82. PMID: 18234668; PMCID: PMC2276381.
    52. Serrano AL, Jardi M, Suelves M, Klotman PE, Munoz-Canoves P. HIV-1 transgenic expression in mice induces selective atrophy of fast-glycolytic skeletal muscle fibers. Front Biosci. 2008; 13:2797-805. PMID: 17981754.
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    53. Wyatt CM, Rosenstiel PE, Klotman PE. HIV-associated nephropathy. Contrib Nephrol. 2008; 159:151-61. PMID: 18391591.
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    54. Wyatt CM, Winston JA, Malvestutto CD, Fishbein DA, Barash I, Cohen AJ, Klotman ME, Klotman PE. Chronic kidney disease in HIV infection: an urban epidemic. AIDS. 2007 Oct 1; 21(15):2101-3. PMID: 17885301.
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    55. Wyatt CM, Klotman PE. HIV-1 and HIV-Associated Nephropathy 25 Years Later. Clin J Am Soc Nephrol. 2007 Jul; 2 Suppl 1:S20-4. PMID: 17699507.
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    56. Mosoian A, Teixeira A, Burns CS, Khitrov G, Zhang W, Gusella L, Klotman P, Klotman M. Influence of prothymosin-alpha on HIV-1 target cells. Ann N Y Acad Sci. 2007 Sep; 1112:269-85. PMID: 17600282.
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    57. Wyatt CM, Rodriguez-Caprio G, Klotman PE. Efavirenz: innocent bystander or direct nephrotoxin? AIDS. 2007 Jun 19; 21(10):1393. PMID: 17545729.
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    58. Lu TC, He JC, Klotman PE. Podocytes in HIV-associated nephropathy. Nephron Clin Pract. 2007; 106(2):c67-71. PMID: 17570932.
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    59. Wyatt CM, Klotman PE. HIV-associated nephropathy in the era of antiretroviral therapy. Am J Med. 2007 Jun; 120(6):488-92. PMID: 17524746.
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    60. Kaufman L, Yang G, Hayashi K, Ashby JR, Huang L, Ross MJ, Klotman ME, Klotman PE. The homophilic adhesion molecule sidekick-1 contributes to augmented podocyte aggregation in HIV-associated nephropathy. FASEB J. 2007 May; 21(7):1367-75. PMID: 17307840.
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    61. Sax PE, Gallant JE, Klotman PE. Renal safety of tenofovir disoproxil fumarate. AIDS Read. 2007 Feb; 17(2):90-2, 99-104, C3. PMID: 17323508.
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    62. He JC, Lu TC, Fleet M, Sunamoto M, Husain M, Fang W, Neves S, Chen Y, Shankland S, Iyengar R, Klotman PE. Retinoic acid inhibits HIV-1-induced podocyte proliferation through the cAMP pathway. J Am Soc Nephrol. 2007 Jan; 18(1):93-102. PMID: 17182884; PMCID: PMC3197239.
    63. Shah SN, He CJ, Klotman P. Update on HIV-associated nephropathy. Curr Opin Nephrol Hypertens. 2006 Jul; 15(4):450-5. PMID: 16775461.
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    64. Wyatt CM, Klotman PE. HIV-associated nephropathy: a case study in race and genetics. Am J Kidney Dis. 2006 Jun; 47(6):1084-5; author reply 1085. PMID: 16731307.
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    65. Lu TC, He JC, Klotman P. Animal models of HIV-associated nephropathy. Curr Opin Nephrol Hypertens. 2006 May; 15(3):233-7. PMID: 16609288.
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    66. Ross MJ, Fan C, Ross MD, Chu TH, Shi Y, Kaufman L, Zhang W, Klotman ME, Klotman PE. HIV-1 infection initiates an inflammatory cascade in human renal tubular epithelial cells. J Acquir Immune Defic Syndr. 2006 May; 42(1):1-11. PMID: 16763488.
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    67. Tanji N, Ross MD, Tanji K, Bruggeman LA, Markowitz GS, Klotman PE, D'Agati VD. Detection and localization of HIV-1 DNA in renal tissues by in situ polymerase chain reaction. Histol Histopathol. 2006 Apr; 21(4):393-401. PMID: 16437385.
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    68. Wyatt CM, Klotman PE. Antiretroviral therapy and the kidney: balancing benefit and risk in patients with HIV infection. Expert Opin Drug Saf. 2006 Mar; 5(2):275-87. PMID: 16503748.
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    69. Zerhouni-Layachi B, Husain M, Ross MJ, Marras D, Sunamoto M, Liu X, Klotman PE, Klotman ME. Dual tropism of HIV-1 envelopes derived from renal tubular epithelial cells of patients with HIV-associated nephropathy. AIDS. 2006 Feb 28; 20(4):621-4. PMID: 16470129.
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    70. Wyatt CM, Arons RR, Klotman PE, Klotman ME. Acute renal failure in hospitalized patients with HIV: risk factors and impact on in-hospital mortality. AIDS. 2006 Feb 28; 20(4):561-5. PMID: 16470120.
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    71. Ross MJ, Wosnitzer MS, Ross MD, Granelli B, Gusella GL, Husain M, Kaufman L, Vasievich M, D'Agati VD, Wilson PD, Klotman ME, Klotman PE. Role of ubiquitin-like protein FAT10 in epithelial apoptosis in renal disease. J Am Soc Nephrol. 2006 Apr; 17(4):996-1004. PMID: 16495380.
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    72. Husain M, D'Agati VD, He JC, Klotman ME, Klotman PE. HIV-1 Nef induces dedifferentiation of podocytes in vivo: a characteristic feature of HIVAN. AIDS. 2005 Nov 18; 19(17):1975-80. PMID: 16260903.
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    73. Schwartz EJ, Szczech LA, Ross MJ, Klotman ME, Winston JA, Klotman PE. Highly active antiretroviral therapy and the epidemic of HIV+ end-stage renal disease. J Am Soc Nephrol. 2005 Aug; 16(8):2412-20. PMID: 15987747.
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    74. Gupta SK, Eustace JA, Winston JA, Boydstun II, Ahuja TS, Rodriguez RA, Tashima KT, Roland M, Franceschini N, Palella FJ, Lennox JL, Klotman PE, Nachman SA, Hall SD, Szczech LA. Guidelines for the management of chronic kidney disease in HIV-infected patients: recommendations of the HIV Medicine Association of the Infectious Diseases Society of America. Clin Infect Dis. 2005 Jun 1; 40(11):1559-85. PMID: 15889353.
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    75. Leal-Pinto E, Teixeira A, Tran B, Hanss B, Klotman PE. Presence of the nucleic acid channel in renal brush-border membranes: allosteric modulation by extracellular calcium. Am J Physiol Renal Physiol. 2005 Jul; 289(1):F97-106. PMID: 15727991.
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    76. Hayashi K, Kaufman L, Ross MD, Klotman PE. Definition of the critical domains required for homophilic targeting of mouse sidekick molecules. FASEB J. 2005 Apr; 19(6):614-6. PMID: 15703275.
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    77. He JC, Husain M, Sunamoto M, D'Agati VD, Klotman ME, Iyengar R, Klotman PE. Nef stimulates proliferation of glomerular podocytes through activation of Src-dependent Stat3 and MAPK1,2 pathways. J Clin Invest. 2004 Sep; 114(5):643-51. PMID: 15343382; PMCID: PMC514582.
    78. Szczech LA, Gupta SK, Habash R, Guasch A, Kalayjian R, Appel R, Fields TA, Svetkey LP, Flanagan KH, Klotman PE, Winston JA. The clinical epidemiology and course of the spectrum of renal diseases associated with HIV infection. Kidney Int. 2004 Sep; 66(3):1145-52. PMID: 15327410.
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    79. Kaufman L, Hayashi K, Ross MJ, Ross MD, Klotman PE. Sidekick-1 is upregulated in glomeruli in HIV-associated nephropathy. J Am Soc Nephrol. 2004 Jul; 15(7):1721-30. PMID: 15213259.
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    80. Ross MJ, Klotman PE. HIV-associated nephropathy. AIDS. 2004 May 21; 18(8):1089-99. PMID: 15166524.
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    81. Gharavi AG, Ahmad T, Wong RD, Hooshyar R, Vaughn J, Oller S, Frankel RZ, Bruggeman LA, D'Agati VD, Klotman PE, Lifton RP. Mapping a locus for susceptibility to HIV-1-associated nephropathy to mouse chromosome 3. Proc Natl Acad Sci U S A. 2004 Feb 24; 101(8):2488-93. PMID: 14983036; PMCID: PMC356977.
    82. Richardson MW, Hostalek L, Dobson M, Hu J, Shippy R, Siwkowski A, Marmur JD, Khalili K, Klotman PE, Hampel A, Rappaport J. Design, targeting, and initial screening of sTRSV-derived hairpin ribozymes for optimum helix 1 length and catalytic efficiency in vitro. Methods Mol Biol. 2004; 252:339-58. PMID: 15017062.
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    83. Sunamoto M, Husain M, He JC, Schwartz EJ, Klotman PE. Critical role for Nef in HIV-1-induced podocyte dedifferentiation. Kidney Int. 2003 Nov; 64(5):1695-701. PMID: 14531802.
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    84. Ross MD, Bruggeman LA, Hanss B, Sunamoto M, Marras D, Klotman ME, Klotman PE. Podocan, a novel small leucine-rich repeat protein expressed in the sclerotic glomerular lesion of experimental HIV-associated nephropathy. J Biol Chem. 2003 Aug 29; 278(35):33248-55. PMID: 12796502.
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    85. Herman ES, Klotman PE. HIV-associated nephropathy: Epidemiology, pathogenesis, and treatment. Semin Nephrol. 2003 Mar; 23(2):200-8. PMID: 12704580.
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    86. Ross MJ, Klotman PE. Recent progress in HIV-associated nephropathy. J Am Soc Nephrol. 2002 Dec; 13(12):2997-3004. PMID: 12444220.
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    87. Cusumano AM, Bodkin NL, Hansen BC, Iotti R, Owens J, Klotman PE, Kopp JB. Glomerular hypertrophy is associated with hyperinsulinemia and precedes overt diabetes in aging rhesus monkeys. Am J Kidney Dis. 2002 Nov; 40(5):1075-85. PMID: 12407654.
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    88. Husain M, Gusella GL, Klotman ME, Gelman IH, Ross MD, Schwartz EJ, Cara A, Klotman PE. HIV-1 Nef induces proliferation and anchorage-independent growth in podocytes. J Am Soc Nephrol. 2002 Jul; 13(7):1806-15. PMID: 12089376.
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    89. Coller BS, Klotman P, Smith LG. Professing and living the oath: teaching medicine as a profession. Am J Med. 2002 Jun 15; 112(9):744-8. PMID: 12079723.
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    90. Schwartz EJ, Fierer DS, Neumann AU, Keller MJ, Parkas V, Zhang DY, Klotman ME, Winston JA, Klotman PE. HIV-1 dynamics in haemodialysis patients. AIDS. 2002 Jun 14; 16(9):1301-3. PMID: 12045502.
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    91. Klotman P, Klotman M. Editorial comment: renal insufficiency in HIV-infected patients may not always be HIVAN. AIDS Read. 2002 Jun; 12(6):273. PMID: 12138882.
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    92. Marras D, Bruggeman LA, Gao F, Tanji N, Mansukhani MM, Cara A, Ross MD, Gusella GL, Benson G, D'Agati VD, Hahn BH, Klotman ME, Klotman PE. Replication and compartmentalization of HIV-1 in kidney epithelium of patients with HIV-associated nephropathy. Nat Med. 2002 May; 8(5):522-6. PMID: 11984599.
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    93. Schwartz EJ, Neumann AU, Teixeira AV, Bruggeman LA, Rappaport J, Perelson AS, Klotman PE. Effect of target cell availability on HIV-1 production in vitro. AIDS. 2002 Feb 15; 16(3):341-5. PMID: 11834944.
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    94. Gusella GL, Fedorova E, Hanss B, Marras D, Klotman ME, Klotman PE. Lentiviral gene transduction of kidney. Hum Gene Ther. 2002 Feb 10; 13(3):407-14. PMID: 11860707.
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    95. Hanss B, Leal-Pinto E, Teixeira A, Christian RE, Shabanowitz J, Hunt DF, Klotman PE. Cytosolic malate dehydrogenase confers selectivity of the nucleic acid-conducting channel. Proc Natl Acad Sci U S A. 2002 Feb 5; 99(3):1707-12. PMID: 11805283; PMCID: PMC122255.
    96. Woo S, Klotman P. Gene therapy and renal disease. Introduction. Kidney Int. 2002 Jan; 61(1 Suppl):S1-2. PMID: 11841604.
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    97. Gusella GL, Fedorova E, Marras D, Klotman PE, Klotman ME. In vivo gene transfer to kidney by lentiviral vector. Kidney Int. 2002 Jan; 61(1 Suppl):S32-6. PMID: 11841609.
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    98. Stern AS, Klotman ME, Ioannou YA, Burrow CR, Wilson PD, Klotman PE, Lipkowitz MS. Polarity of alpha-galactosidase A uptake by renal tubule cells. Kidney Int. 2002 Jan; 61(1 Suppl):S52-5. PMID: 11841613.
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    99. Ross MJ, Bruggeman LA, Wilson PD, Klotman PE. Microcyst formation and HIV-1 gene expression occur in multiple nephron segments in HIV-associated nephropathy. J Am Soc Nephrol. 2001 Dec; 12(12):2645-51. PMID: 11729233.
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    100. Nelson PJ, Gelman IH, Klotman PE. Suppression of HIV-1 expression by inhibitors of cyclin-dependent kinases promotes differentiation of infected podocytes. J Am Soc Nephrol. 2001 Dec; 12(12):2827-31. PMID: 11729253.
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    101. Schwartz EJ, Cara A, Snoeck H, Ross MD, Sunamoto M, Reiser J, Mundel P, Klotman PE. Human immunodeficiency virus-1 induces loss of contact inhibition in podocytes. J Am Soc Nephrol. 2001 Aug; 12(8):1677-84. PMID: 11461940.
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    102. Monahan M, Tanji N, Klotman PE. HIV-associated nephropathy: an urban epidemic. Semin Nephrol. 2001 Jul; 21(4):394-402. PMID: 11455528.
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    103. Winston JA, Bruggeman LA, Ross MD, Jacobson J, Ross L, D'Agati VD, Klotman PE, Klotman ME. Nephropathy and establishment of a renal reservoir of HIV type 1 during primary infection. N Engl J Med. 2001 Jun 28; 344(26):1979-84. PMID: 11430327.
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    104. Bruggeman LA, Adler SH, Klotman PE. Nuclear factor-kappa B binding to the HIV-1 LTR in kidney: implications for HIV-associated nephropathy. Kidney Int. 2001 Jun; 59(6):2174-81. PMID: 11380819.
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    105. Tanji N, Ross MD, Cara A, Markowitz GS, Klotman PE, D'Agati VD. Effect of tissue processing on the ability to recover nucleic acid from specific renal tissue compartments by laser capture microdissection. Exp Nephrol. 2001; 9(3):229-34. PMID: 11340308.
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    106. Ross MJ, Klotman PE, Winston JA. HIV-associated nephropathy: case study and review of the literature. AIDS Patient Care STDS. 2000 Dec; 14(12):637-45. PMID: 11119430.
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    107. Bruggeman LA, Ross MD, Tanji N, Cara A, Dikman S, Gordon RE, Burns GC, D'Agati VD, Winston JA, Klotman ME, Klotman PE. Renal epithelium is a previously unrecognized site of HIV-1 infection. J Am Soc Nephrol. 2000 Nov; 11(11):2079-87. PMID: 11053484.
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    108. Kajiyama W, Kopp JB, Marinos NJ, Klotman PE, Dickie P. Glomerulosclerosis and viral gene expression in HIV-transgenic mice: role of nef. Kidney Int. 2000 Sep; 58(3):1148-59. PMID: 10972678.
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    109. Barisoni L, Bruggeman LA, Mundel P, D'Agati VD, Klotman PE. HIV-1 induces renal epithelial dedifferentiation in a transgenic model of HIV-associated nephropathy. Kidney Int. 2000 Jul; 58(1):173-81. PMID: 10886562.
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    110. Winston JA, Burns GC, Klotman PE. Treatment of HIV-associated nephropathy. Semin Nephrol. 2000 May; 20(3):293-8. PMID: 10855939.
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    111. Lewis W, Grupp IL, Grupp G, Hoit B, Morris R, Samarel AM, Bruggeman L, Klotman P. Cardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudine. Lab Invest. 2000 Feb; 80(2):187-97. PMID: 10701688.
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    112. Lipkowitz MS, Hanss B, Tulchin N, Wilson PD, Langer JC, Ross MD, Kurtzman GJ, Klotman PE, Klotman ME. Transduction of renal cells in vitro and in vivo by adeno-associated virus gene therapy vectors. J Am Soc Nephrol. 1999 Sep; 10(9):1908-15. PMID: 10477142.
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    113. Klotman PE. HIV-associated nephropathy. Kidney Int. 1999 Sep; 56(3):1161-76. PMID: 10469389.
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    114. Mannon RB, Kopp JB, Ruiz P, Griffiths R, Bustos M, Platt JL, Klotman PE, Coffman TM. Chronic rejection of mouse kidney allografts. Kidney Int. 1999 May; 55(5):1935-44. PMID: 10231457.
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    115. Winston JA, Klotman ME, Klotman PE. HIV-associated nephropathy is a late, not early, manifestation of HIV-1 infection. Kidney Int. 1999 Mar; 55(3):1036-40. PMID: 10027941.
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    116. Nelson PJ, Moissoglu K, Vargas J, Klotman PE, Gelman IH. Involvement of the protein kinase C substrate, SSeCKS, in the actin-based stellate morphology of mesangial cells. J Cell Sci. 1999 Feb; 112 ( Pt 3):361-70. PMID: 9885289.
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    117. Singhal PC, Sharma P, Loona R, Gibbons N, Franki N, Klotman PE. Enhanced proliferation, apoptosis, and matrix accumulation by mesangial cells derived from HIV-1 transgenic mice. J Investig Med. 1998 Aug; 46(6):297-302. PMID: 9737092.
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    118. Klotman ME, Klotman PE. AIDS and the kidney. Introduction. Semin Nephrol. 1998 Jul; 18(4):371-2. PMID: 9692349.
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    119. Schwartz EJ, Klotman PE. Pathogenesis of human immunodeficiency virus (HIV)-associated nephropathy. Semin Nephrol. 1998 Jul; 18(4):436-45. PMID: 9692355.
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    120. Winston JA, Burns GC, Klotman PE. The human immunodeficiency virus (HIV) epidemic and HIV-associated nephropathy. Semin Nephrol. 1998 Jul; 18(4):373-7. PMID: 9692350.
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    121. Langer JC, Klotman ME, Hanss B, Tulchin N, Bruggeman LA, Klotman PE, Lipkowitz MS. Adeno-associated virus gene transfer into renal cells: potential for in vivo gene delivery. Exp Nephrol. 1998 May-Jun; 6(3):189-94. PMID: 9639033.
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    122. Klotman PE. Early treatment with ACE inhibition may benefit HIV-associated nephropathy patients. Am J Kidney Dis. 1998 Apr; 31(4):719-20; discussion 720-2. PMID: 9531193.
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    123. Gharavi A, Klotman P. The renin-angiotensin system as a mediator of renal injury in hypertension. Mt Sinai J Med. 1998 Mar; 65(2):118-24. PMID: 9520515.
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    124. Hanss B, Leal-Pinto E, Bruggeman LA, Copeland TD, Klotman PE. Identification and characterization of a cell membrane nucleic acid channel. Proc Natl Acad Sci U S A. 1998 Feb 17; 95(4):1921-6. PMID: 9465118; PMCID: PMC19214.
    125. Branch AD, Klotman PE. Optimizing ribozymes for somatic cell gene therapy. Exp Nephrol. 1998 Jan-Feb; 6(1):78-83. PMID: 9523177.
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    126. Winston J, Klotman PE. HIV-associated nephropathy. Mt Sinai J Med. 1998 Jan; 65(1):27-32. PMID: 9458681.
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    127. Bruggeman LA, Dikman S, Meng C, Quaggin SE, Coffman TM, Klotman PE. Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression. J Clin Invest. 1997 Jul 1; 100(1):84-92. PMID: 9202060; PMCID: PMC508168.
    128. Bódi I, Kimmel PL, Abraham AA, Svetkey LP, Klotman PE, Kopp JB. Renal TGF-beta in HIV-associated kidney diseases. Kidney Int. 1997 May; 51(5):1568-77. PMID: 9150474.
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    129. Leal-Pinto E, Hanss B, Klotman PE. Calcium regulation of a cell surface nucleic acid channel. Kidney Int Suppl. 1996 Dec; 57:S4-10. PMID: 8941915.
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    130. Lipkowitz MS, Klotman ME, Bruggeman LA, Nicklin P, Hanss B, Rappaport J, Klotman PE. Molecular therapy for renal diseases. Am J Kidney Dis. 1996 Oct; 28(4):475-92. PMID: 8840936.
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    131. Schnaper HW, Kopp JB, Poncelet AC, Hubchak SC, Stetler-Stevenson WG, Klotman PE, Kleinman HK. Increased expression of extracellular matrix proteins and decreased expression of matrix proteases after serial passage of glomerular mesangial cells. J Cell Sci. 1996 Oct; 109 ( Pt 10):2521-8. PMID: 8923213.
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    132. Kopp JB, Factor VM, Mozes M, Nagy P, Sanderson N, Böttinger EP, Klotman PE, Thorgeirsson SS. Transgenic mice with increased plasma levels of TGF-beta 1 develop progressive renal disease. Lab Invest. 1996 Jun; 74(6):991-1003. PMID: 8667617.
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    133. Klotman PE, Notkins AL. Transgenic models of human immunodeficiency virus type-1. Curr Top Microbiol Immunol. 1996; 206:197-222. PMID: 8608718.
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    134. Ray PE, McCune BK, Geary KM, Carey RM, Klotman PE, Gomez RA. Modulation of renin release and renal vascular smooth muscle cell contractility by TGF-beta 2. Contrib Nephrol. 1996; 118:238-48. PMID: 8744064.
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    135. Emovon OE, Klotman PE, Dunnick NR, Kadir S, Svetkey LP. Renovascular hypertension in blacks. Am J Hypertens. 1996 Jan; 9(1):18-23. PMID: 8834702.
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    136. Winston JA, Klotman PE. Are we missing an epidemic of HIV-associated nephropathy? J Am Soc Nephrol. 1996 Jan; 7(1):1-7. PMID: 8808103.
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    137. Rappaport J, Arya SK, Richardson MW, Baier-Bitterlich G, Klotman PE. Inhibition of HIV-1 expression by HIV-2. J Mol Med (Berl). 1995 Dec; 73(12):583-9. PMID: 8825754.
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    138. Kopp JB, Klotman PE. Transgenic animal models of renal development and pathogenesis. Am J Physiol. 1995 Nov; 269(5 Pt 2):F601-20. PMID: 7503226.
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    139. Rappaport J, Hanss B, Kopp JB, Copeland TD, Bruggeman LA, Coffman TM, Klotman PE. Transport of phosphorothioate oligonucleotides in kidney: implications for molecular therapy. Kidney Int. 1995 May; 47(5):1462-9. PMID: 7637275.
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    140. Klotman PE, Rappaport J, Ray P, Kopp JB, Franks R, Bruggeman LA, Notkins AL. Transgenic models of HIV-1. AIDS. 1995 Apr; 9(4):313-24. PMID: 7794536.
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    141. Franks RR, Ray PE, Babbott CC, Bryant JL, Notkins AL, Santoro TJ, Klotman PE. Maternal-fetal interactions affect growth of human immunodeficiency virus type 1 transgenic mice. Pediatr Res. 1995 Jan; 37(1):56-63. PMID: 7700734.
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    142. Ray PE, Bruggeman LA, Weeks BS, Kopp JB, Bryant JL, Owens JW, Notkins AL, Klotman PE. bFGF and its low affinity receptors in the pathogenesis of HIV-associated nephropathy in transgenic mice. Kidney Int. 1994 Sep; 46(3):759-72. PMID: 7996798.
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    143. Bruggeman LA, Thomson MM, Nelson PJ, Kopp JB, Rappaport J, Klotman PE, Klotman ME. Patterns of HIV-1 mRNA expression in transgenic mice are tissue-dependent. Virology. 1994 Aug 1; 202(2):940-8. PMID: 7518165.
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    144. Sei S, Kleiner DE, Kopp JB, Chandra R, Klotman PE, Yarchoan R, Pizzo PA, Mitsuya H. Quantitative analysis of viral burden in tissues from adults and children with symptomatic human immunodeficiency virus type 1 infection assessed by polymerase chain reaction. J Infect Dis. 1994 Aug; 170(2):325-33. PMID: 8035018.
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    145. Rappaport J, Kopp JB, Klotman PE. Host virus interactions and the molecular regulation of HIV-1: role in the pathogenesis of HIV-associated nephropathy. Kidney Int. 1994 Jul; 46(1):16-27. PMID: 7933833.
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    146. Santoro TJ, Bryant JL, Pellicoro J, Klotman ME, Kopp JB, Bruggeman LA, Franks RR, Notkins AL, Klotman PE. Growth failure and AIDS-like cachexia syndrome in HIV-1 transgenic mice. Virology. 1994 May 15; 201(1):147-51. PMID: 7909972.
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    147. Ray PE, McCune B, Gomez RA, Bruggeman LA, Klotman PE. Induction of transforming growth factor-beta 2-3 in the juxtaglomerular apparatus and renal vascular smooth muscle cells of young rats and infants. Exp Nephrol. 1994 Mar-Apr; 2(2):129. PMID: 8082006.
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    148. Spurney RF, Ibrahim S, Butterly D, Klotman PE, Sanfilippo F, Coffman TM. Leukotrienes in renal transplant rejection in rats. Distinct roles for leukotriene B4 and peptidoleukotrienes in the pathogenesis of allograft injury. J Immunol. 1994 Jan 15; 152(2):867-76. PMID: 8283057.
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    149. Ray PE, McCune BK, Gomez RA, Ruley EJ, Klotman PE. Expression of transforming growth factor beta 3 in hypertrophic juxtaglomerular apparatus. N Engl J Med. 1994 Jan 6; 330(1):68-9. PMID: 8259157.
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    150. Ray PE, Bruggeman LA, Horikoshi S, Aguilera G, Klotman PE. Angiotensin II stimulates human fetal mesangial cell proliferation and fibronectin biosynthesis by binding to AT1 receptors. Kidney Int. 1994 Jan; 45(1):177-84. PMID: 8127007.
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    151. Kopp JB, Ray PE, Adler SH, Bruggeman LA, Mangurian CV, Owens JW, Eckhaus MA, Bryant JL, Klotman PE. Nephropathy in HIV-transgenic mice. Contrib Nephrol. 1994; 107:194-204. PMID: 8004968.
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    152. Weeks BS, Holloway E, Klotman PE, Akiyama SK, Schnaper HW, Kleinman HK. 12-O-tetradecanoylphorbol 13-acetate stimulates human T-lymphocyte adherence to the fibronectin RGD domain and the laminin IKVAV domain. Cell Immunol. 1994 Jan; 153(1):94-104. PMID: 8287495.
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    153. Dhawan S, Weeks BS, Abbasi F, Gralnick HR, Notkins AL, Klotman ME, Yamada KM, Klotman PE. Increased expression of alpha 4 beta 1 and alpha 5 beta 1 integrins on HTLV-I-infected lymphocytes. Virology. 1993 Dec; 197(2):778-81. PMID: 7504369.
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    154. Ray PE, McCune BK, Gomez RA, Horikoshi S, Kopp JB, Klotman PE. Renal vascular induction of TGF-beta 2 and renin by potassium depletion. Kidney Int. 1993 Nov; 44(5):1006-13. PMID: 7505348.
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    155. Kopp JB, Bruggeman LA, Klotman PE. Extracellular matrix gene expression in experimental glomerulonephritis. Curr Opin Nephrol Hypertens. 1993 Jul; 2(4):609-17. PMID: 7859024.
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    156. Weeks BS, Klotman ME, Holloway E, Stetler-Stevenson WG, Kleinman HK, Klotman PE. HIV-1 infection stimulates T cell invasiveness and synthesis of the 92-kDa type IV collagenase. AIDS Res Hum Retroviruses. 1993 Jun; 9(6):513-8. PMID: 8347396.
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    157. Bruggeman LA, Pellicoro JA, Horigan EA, Klotman PE. Thromboxane and prostacyclin differentially regulate murine extracellular matrix gene expression. Kidney Int. 1993 Jun; 43(6):1219-25. PMID: 8315934.
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    158. Wahl SM, Allen JB, Weeks BS, Wong HL, Klotman PE. Transforming growth factor beta enhances integrin expression and type IV collagenase secretion in human monocytes. Proc Natl Acad Sci U S A. 1993 May 15; 90(10):4577-81. PMID: 8506302; PMCID: PMC46555.
    159. Weeks BS, Desai K, Loewenstein PM, Klotman ME, Klotman PE, Green M, Kleinman HK. Identification of a novel cell attachment domain in the HIV-1 Tat protein and its 90-kDa cell surface binding protein. J Biol Chem. 1993 Mar 5; 268(7):5279-84. PMID: 8444901.
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    160. Kopp JB, Rooney JF, Wohlenberg C, Dorfman N, Marinos NJ, Bryant JL, Katz SI, Notkins AL, Klotman PE. Cutaneous disorders and viral gene expression in HIV-1 transgenic mice. AIDS Res Hum Retroviruses. 1993 Mar; 9(3):267-75. PMID: 8471318.
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    161. Horikoshi S, Fukuda K, Ray PE, Sawada M, Bruggeman LA, Klotman PE. A PCR method for the quantitative assessment of mRNA for laminin A, B1, and B2 chains. Kidney Int. 1992 Sep; 42(3):764-9. PMID: 1405354.
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    162. Bruggeman LA, Burbelo PD, Yamada Y, Klotman PE. A novel sequence in the type IV collagen promoter binds nuclear proteins from Engelbreth-Holm-Swarm tumor. Oncogene. 1992 Aug; 7(8):1497-502. PMID: 1630813.
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    163. Kopp JB, Klotman ME, Adler SH, Bruggeman LA, Dickie P, Marinos NJ, Eckhaus M, Bryant JL, Notkins AL, Klotman PE. Progressive glomerulosclerosis and enhanced renal accumulation of basement membrane components in mice transgenic for human immunodeficiency virus type 1 genes. Proc Natl Acad Sci U S A. 1992 Mar 1; 89(5):1577-81. PMID: 1542649; PMCID: PMC48495.
    164. Smith SR, Klotman PE, Svetkey LP. Potassium chloride lowers blood pressure and causes natriuresis in older patients with hypertension. J Am Soc Nephrol. 1992 Feb; 2(8):1302-9. PMID: 1627756.
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    165. Smith SR, Creech EA, Schaffer AV, Martin LL, Rakhit A, Douglas FL, Klotman PE, Coffman TM. Effects of thromboxane synthase inhibition with CGS 13080 in human cyclosporine nephrotoxicity. Kidney Int. 1992 Jan; 41(1):199-205. PMID: 1593856.
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    166. Svetkey LP, Wilkinson R, Dunnick NR, Smith SR, Dunham CB, Lambert M, Klotman PE. Captopril renography in the diagnosis of renovascular disease. Am J Hypertens. 1991 Dec; 4(12 Pt 2):711S-715S. PMID: 1777184.
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    167. Horikoshi S, McCune BK, Ray PE, Kopp JB, Sporn MB, Klotman PE. Water deprivation stimulates transforming growth factor-beta 2 accumulation in the juxtaglomerular apparatus of mouse kidney. J Clin Invest. 1991 Dec; 88(6):2117-22. PMID: 1752966; PMCID: PMC295816.
    168. Burbelo PD, Bruggeman LA, Gabriel GC, Klotman PE, Yamada Y. Characterization of a cis-acting element required for efficient transcriptional activation of the collagen IV enhancer. J Biol Chem. 1991 Nov 25; 266(33):22297-302. PMID: 1939251.
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    169. Weeks BS, Kopp JB, Horikoshi S, Cannon FB, Garrett M, Kleinman HK, Klotman PE. Adult and fetal human mesangial cells interact with specific laminin domains. Am J Physiol. 1991 Oct; 261(4 Pt 2):F688-95. PMID: 1928380.
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    170. Ray PE, Aguilera G, Kopp JB, Horikoshi S, Klotman PE. Angiotensin II receptor-mediated proliferation of cultured human fetal mesangial cells. Kidney Int. 1991 Oct; 40(4):764-71. PMID: 1745028.
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    171. Bruggeman LA, Horigan EA, Horikoshi S, Ray PE, Klotman PE. Thromboxane stimulates synthesis of extracellular matrix proteins in vitro. Am J Physiol. 1991 Sep; 261(3 Pt 2):F488-94. PMID: 1887910.
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    172. Weeks BS, Klotman ME, Dhawan S, Kibbey M, Rappaport J, Kleinman HK, Yamada KM, Klotman PE. HIV-1 infection of human T lymphocytes results in enhanced alpha 5 beta 1 integrin expression. J Cell Biol. 1991 Aug; 114(4):847-53. PMID: 1831204; PMCID: PMC2289886.
    173. Bruggeman LA, Horikoshi S, Burbelo PD, Yamada Y, Klotman PE. Physiology and cell biology update: mechanisms of type IV collagen gene regulation. Am J Kidney Dis. 1991 Jul; 18(1):134-9. PMID: 2063849.
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    174. Svetkey LP, Kadir S, Dunnick NR, Smith SR, Dunham CB, Lambert M, Klotman PE. Similar prevalence of renovascular hypertension in selected blacks and whites. Hypertension. 1991 May; 17(5):678-83. PMID: 2022411.
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    175. Roubidoux MA, Dunnick NR, Klotman PE, Newman GE, Cohan RH, Kadir S, Svetkey LP. Renal vein renins: inability to predict response to revascularization in patients with hypertension. Radiology. 1991 Mar; 178(3):819-22. PMID: 1994424.
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    176. Horikoshi S, Kubota S, Martin GR, Yamada Y, Klotman PE. Epidermal growth factor (EGF) expression in the congenital polycystic mouse kidney. Kidney Int. 1991 Jan; 39(1):57-62. PMID: 2002633.
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    177. Kopp JB, Klotman PE. Cellular and molecular mechanisms of cyclosporin nephrotoxicity. J Am Soc Nephrol. 1990 Aug; 1(2):162-79. PMID: 2104260.
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    178. Svetkey LP, Helms MJ, Dunnick NR, Klotman PE. Clinical characteristics useful in screening for renovascular disease. South Med J. 1990 Jul; 83(7):743-7. PMID: 2371594.
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    179. Himmelstein SI, Coffman TM, Yarger WE, Klotman PE. Atrial natriuretic peptide-induced changes in renal prostacyclin production in ureteral obstruction. Am J Physiol. 1990 Feb; 258(2 Pt 2):F281-6. PMID: 2137982.
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    180. Spurney RF, Mayros SD, Collins D, Ruiz P, Klotman PE, Coffman T. Thromboxane receptor blockade improves cyclosporine nephrotoxicity in rats. Prostaglandins. 1990 Feb; 39(2):135-46. PMID: 2138344.
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    181. Klotman ME, Henry SC, Greene RC, Brazy PC, Klotman PE, Hamilton JD. Detection of mouse cytomegalovirus nucleic acid in latently infected mice by in vitro enzymatic amplification. J Infect Dis. 1990 Feb; 161(2):220-5. PMID: 2153738.
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    182. Burbelo PD, Klotman P, Bruggeman L, Clément B, Yamada Y. Regulation of basement membrane genes. Crit Rev Eukaryot Gene Expr. 1990; 1(1):1-10. PMID: 2134347.
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    183. Brazy PC, Klotman PE. Increased oxidative metabolism in renal tubules from spontaneously hypertensive rats. Am J Physiol. 1989 Nov; 257(5 Pt 2):F818-25. PMID: 2589484.
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    184. Collins DM, Coffman TM, Ruiz P, Klotman PE. High-protein feeding stimulates renal thromboxane production in rats with streptozocin-induced diabetes. J Lab Clin Med. 1989 Nov; 114(5):545-53. PMID: 2809397.
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    185. Ruiz P, Coffman TM, Klotman PE, Sanfilippo F. Association of chronic thromboxane inhibition with reduced in situ cytotoxic T cell activity in rejecting rat renal allografts. Transplantation. 1989 Oct; 48(4):660-6. PMID: 2799920.
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    186. Svetkey LP, Himmelstein SI, Dunnick NR, Wilkinson RH, Bollinger RR, McCann RL, Beytas EM, Klotman PE. Prospective analysis of strategies for diagnosing renovascular hypertension. Hypertension. 1989 Sep; 14(3):247-57. PMID: 2670763.
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    187. Himmelstein SI, Klotman PE. The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats. Am J Physiol. 1989 Aug; 257(2 Pt 2):F190-6. PMID: 2527469.
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    188. Coffman TM, Himmelstein S, Best C, Klotman PE. Post-transplant hypertension in the rat: effects of captopril and native nephrectomy. Kidney Int. 1989 Jul; 36(1):35-40. PMID: 2681927.
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    189. Almond JR, Bales CW, Lobaugh B, Klotman PE, Drezner MK. Regulation of renal 25-hydroxyvitamin D-1-hydroxylase activity in the mouse after uninephrectomy. Endocrinology. 1989 May; 124(5):2118-21. PMID: 2707150.
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    190. Dunnick NR, Svetkey LP, Cohan RH, Newman GE, Braun SD, Himmelstein SI, Bollinger RR, McCann RL, Wilkinson RH, Klotman PE. Intravenous digital subtraction renal angiography: use in screening for renovascular hypertension. Radiology. 1989 Apr; 171(1):219-22. PMID: 2648471.
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    191. Coffman TM, Ruiz P, Sanfilippo F, Klotman PE. Chronic thromboxane inhibition preserves function of rejecting rat renal allografts. Kidney Int. 1989 Jan; 35(1):24-30. PMID: 2651752.
      View in: PubMed
    192. Cubeddu LX, Pool JL, Bloomfield R, Klotman PE, Pickering BI, Wombolt DG, Nelson EB, Halperin A. Effect of doxazosin monotherapy on blood pressure and plasma lipids in patients with essential hypertension. Am J Hypertens. 1988 Apr; 1(2):158-67. PMID: 2969740.
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    193. Coffman TM, Yohay D, Carr DR, Brazy PC, Yarger WE, Klotman PE. Effect of dietary fish oil supplementation on eicosanoid production by rat renal allografts. Transplantation. 1988 Feb; 45(2):470-4. PMID: 3125638.
      View in: PubMed
    194. Ruiz P, Coffman TM, Howell DN, Straznickas J, Scroggs MW, Baldwin WM, Klotman PE, Sanfilippo F. Evidence that pretransplant donor blood transfusion prevents rat renal allograft dysfunction but not the in situ cellular alloimmune or morphologic manifestations of rejection. Transplantation. 1988 Jan; 45(1):1-7. PMID: 3276038.
      View in: PubMed
    195. Svetkey LP, Weinberger MH, Gavras H, Gavras I, Brown TS, Deterding J, Klotman PE. Double-blind, placebo-controlled trial of twice-daily nifedipine as a step-2 agent in mild essential hypertension. J Clin Hypertens. 1987 Dec; 3(4):579-88. PMID: 3330988.
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    196. Yarger WE, Newman WJ, Klotman PE. Renal effects of aprotinin after 24 hours of unilateral ureteral obstruction. Am J Physiol. 1987 Nov; 253(5 Pt 2):F1006-14. PMID: 2446511.
      View in: PubMed
    197. Bauman RP, Rembert JC, Himmelstein SI, Klotman PE, Greenfield JC. Effect of atrial natriuretic factor on transmural myocardial blood flow distribution in the dog. Circulation. 1987 Sep; 76(3):705-9. PMID: 2957114.
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    198. Svetkey LP, Yarger WE, Feussner JR, DeLong E, Klotman PE. Double-blind, placebo-controlled trial of potassium chloride in the treatment of mild hypertension. Hypertension. 1987 May; 9(5):444-50. PMID: 3570421.
      View in: PubMed
    199. Coffman TM, Carr DR, Yarger WE, Klotman PE. Evidence that renal prostaglandin and thromboxane production is stimulated in chronic cyclosporine nephrotoxicity. Transplantation. 1987 Feb; 43(2):282-5. PMID: 3810836.
      View in: PubMed
    200. Kolbeck PC, Scroggs MW, Coffman TM, Klotman PE, Sanfilippo F. Associations between rat renal allograft function, inflammation, and host immunity. Transplant Proc. 1987 Feb; 19(1 Pt 1):379-81. PMID: 3274789.
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    201. Coffman TM, Sanfilippo FP, Brazy PC, Yarger WE, Klotman PE. Bilateral native nephrectomy improves renal isograft function in rats. Kidney Int. 1986 Jul; 30(1):20-6. PMID: 3528617.
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    202. Klotman PE, Smith SR, Volpp BD, Coffman TM, Yarger WE. Thromboxane synthetase inhibition improves function of hydronephrotic rat kidneys. Am J Physiol. 1986 Feb; 250(2 Pt 2):F282-7. PMID: 3456211.
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    203. Brazy PC, Trellis DR, Klotman PE. Bradykinin stimulation of oxidative metabolism in renal cortical tubules from rabbit. Possible role of arachidonic acid. J Clin Invest. 1985 Nov; 76(5):1812-8. PMID: 2997289; PMCID: PMC424214.
    204. Klotman PE, Boatman JE, Volpp BD, Baker JD, Yarger WE. Captopril enhances aminoglycoside nephrotoxicity in potassium-depleted rats. Kidney Int. 1985 Aug; 28(2):118-27. PMID: 2422431.
      View in: PubMed
    205. Coffman TM, Yarger WE, Klotman PE. Functional role of thromboxane production by acutely rejecting renal allografts in rats. J Clin Invest. 1985 Apr; 75(4):1242-8. PMID: 3886703; PMCID: PMC425451.
    206. Klotman PE, Yarger WE. Reduction of renal blood flow and proximal bicarbonate reabsorption in rats by gentamicin. Kidney Int. 1983 Nov; 24(5):638-43. PMID: 6663986.
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    207. Grim CE, Luft FC, Grim CM, Klotman PE, Van Huysse JW, Weinberger MH. Rapid blood pressure control with minoxidil: acute and chronic effects on blood pressure, sodium excretion, and the renin-aldosterone system. Arch Intern Med. 1979 May; 139(5):529-33. PMID: 443947.
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    208. Klotman PE, Grim CE, Weinberger MH, Judson WE. The effects of minoxidil on pulmonary and systemic hemodynamics in hypertensive man. Circulation. 1977 Feb; 55(2):394-400. PMID: 832355.
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