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THOMAS MICHAEL WHEELER

TitleChair
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
DivisionPathology
AddressDepartment of Pathology & Immunology
One Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pathology & Immunology
    DivisionPathology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Urology
    DivisionUrology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wilt TJ, Jones KM, Barry MJ, Andriole GL, Culkin D, Wheeler T, Aronson WJ, Brawer MK. Follow-up of Prostatectomy versus Observation for Early Prostate Cancer. N Engl J Med. 2017 07 13; 377(2):132-142. PMID: 28700844.
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    2. Wang DH, Lee HS, Yoon D, Berry G, Wheeler TM, Sugarbaker DJ, Kheradmand F, Engleman E, Burt BM. Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages. Clin Cancer Res. 2016 Aug 05. PMID: 27496865.
      View in: PubMed
    3. Han RI, Wheeler TM, Lumsden AB, Reardon MJ, Lawrie GM, Grande-Allen KJ, Morrisett JD, Brunner G. Morphometric analysis of calcification and fibrous layer thickness in carotid endarterectomy tissues. Comput Biol Med. 2016 Mar 1; 70:210-9. PMID: 26851729; PMCID: PMC4765924 [Available on 03/01/17].
    4. Gupta S, Black-Schaffer WS, Crawford JM, Gross D, Karcher DS, Kaufman J, Knapman D, Prystowsky MB, Wheeler TM, Bean S, Kumar P, Sharma R, Chamoli V, Ghai V, Gogia V, Weintraub S, Cohen MB, Robboy SJ. An Innovative Interactive Modeling Tool to Analyze Scenario-Based Physician Workforce Supply and Demand. Acad Pathol. 2015 Oct-Dec; 2(4):2374289515606730. PMID: 28725751.
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    5. Delahunt B, Hammond E, Egevad L, Samaratunga H, Srigley JR, Humphrey PA, Rubin M, Epstein JI, Lin DW, Gore JL, Nacey JN, Klotz L, Sandler H, Zietman AL, Holden S, Montironi R, Evans AJ, McKenney JK, Berney D, Wheeler TM, Chinnaiyan AM, True L, Knudsen B, Amin MB. Active surveillance for prostate cancer: the role of the pathologist. Pathology. 2015 Jan; 47(1):1-3. PMID: 25474525.
      View in: PubMed
    6. Montironi R, Hammond EH, Lin DW, Gore JL, Srigley JR, Samaratunga H, Egevad L, Rubin MA, Nacey J, Klotz L, Sandler H, Zietman AL, Holden S, Humphrey PA, Evans AJ, Delahunt B, McKenney JK, Berney D, Wheeler TM, Chinnaiyan A, True L, Knudsen B, Epstein JI, Amin MB. Consensus statement with recommendations on active surveillance inclusion criteria and definition of progression in men with localized prostate cancer: the critical role of the pathologist. Virchows Arch. 2014 Dec; 465(6):623-8. PMID: 25316188.
      View in: PubMed
    7. Iczkowski KA, Egevad L, Ma J, Harding-Jackson N, Algaba F, Billis A, Camparo P, Cheng L, Clouston D, Comperat EM, Datta MW, Evans AG, Griffiths DF, Guo CC, Hailemariam S, Huang W, Humphrey PA, Jiang Z, Kahane H, Kristiansen G, La Rosa FG, Lopez-Beltran A, MacLennan GT, Magi-Galluzzi C, Merrimen J, Montironi R, Osunkoya AO, Picken MM, Rao N, Shah RB, Shanks JH, Shen SS, Tawfik OW, True LD, Van der Kwast T, Varma M, Wheeler TM, Zynger DL, Sahr N, Bostwick DG. Intraductal carcinoma of the prostate: interobserver reproducibility survey of 39 urologic pathologists. Ann Diagn Pathol. 2014 Dec; 18(6):333-42. PMID: 25263387.
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    8. von Rundstedt FC, Lerner SP, Godoy G, Amiel G, Wheeler TM, Truong LD, Shen SS. Usefulness of transurethral biopsy for staging the prostatic urethra before radical cystectomy. J Urol. 2015 Jan; 193(1):58-63. PMID: 25106902; PMCID: PMC4524785.
    9. Amin MB, Lin DW, Gore JL, Srigley JR, Samaratunga H, Egevad L, Rubin M, Nacey J, Carter HB, Klotz L, Sandler H, Zietman AL, Holden S, Montironi R, Humphrey PA, Evans AJ, Epstein JI, Delahunt B, McKenney JK, Berney D, Wheeler TM, Chinnaiyan AM, True L, Knudsen B, Hammond ME. The critical role of the pathologist in determining eligibility for active surveillance as a management option in patients with prostate cancer: consensus statement with recommendations supported by the College of American Pathologists, International Society of Urological Pathology, Association of Directors of Anatomic and Surgical Pathology, the New Zealand Society of Pathologists, and the Prostate Cancer Foundation. Arch Pathol Lab Med. 2014 Oct; 138(10):1387-405. PMID: 25092589.
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    10. San Martin R, Barron DA, Tuxhorn JA, Ressler SJ, Hayward SW, Shen X, Laucirica R, Wheeler TM, Gutierrez C, Ayala GE, Ittmann M, Rowley DR. Recruitment of CD34(+) fibroblasts in tumor-associated reactive stroma: the reactive microvasculature hypothesis. Am J Pathol. 2014 Jun; 184(6):1860-70. PMID: 24713391; PMCID: PMC4044710.
    11. Olar A, He D, Florentin D, Ding Y, Wheeler T, Ayala G. Biological correlates of prostate cancer perineural invasion diameter. Hum Pathol. 2014 Jul; 45(7):1365-9. PMID: 24768607; PMCID: PMC4492300.
    12. McDunn JE, Li Z, Adam KP, Neri BP, Wolfert RL, Milburn MV, Lotan Y, Wheeler TM. Metabolomic signatures of aggressive prostate cancer. Prostate. 2013 Oct; 73(14):1547-60. PMID: 23824564.
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    13. Sonpavde G, Wang M, Peterson LE, Wang HY, Joe T, Mims MP, Kadmon D, Ittmann MM, Wheeler TM, Gee AP, Wang RF, Hayes TG. HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer. Invest New Drugs. 2014 Apr; 32(2):235-42. PMID: 23609828; PMCID: PMC4100683.
    14. Bjurlin MA, Carter HB, Schellhammer P, Cookson MS, Gomella LG, Troyer D, Wheeler TM, Schlossberg S, Penson DF, Taneja SS. Optimization of initial prostate biopsy in clinical practice: sampling, labeling and specimen processing. J Urol. 2013 Jun; 189(6):2039-46. PMID: 23485507; PMCID: PMC3925148.
    15. Kench JG, Delahunt B, Griffiths DF, Humphrey PA, McGowan T, Trpkov K, Varma M, Wheeler TM, Srigley JR. Dataset for reporting of prostate carcinoma in radical prostatectomy specimens: recommendations from the International Collaboration on Cancer Reporting. Histopathology. 2013 Jan; 62(2):203-18. PMID: 23240714.
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    16. Dietrich D, Hasinger O, Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Wernert N, Perner S, Freedland SJ, Corman JM, Ittmann MM, Lark AL, Madden JF, Hartmann A, Schatz P, Kristiansen G. Development and clinical validation of a real-time PCR assay for PITX2 DNA methylation to predict prostate-specific antigen recurrence in prostate cancer patients following radical prostatectomy. J Mol Diagn. 2013 Mar; 15(2):270-9. PMID: 23266319.
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    17. Bonkhoff H, Wheeler TM, van der Kwast TH, Magi-Galluzzi C, Montironi R, Cohen RJ. Intraductal carcinoma of the prostate: precursor or aggressive phenotype of prostate cancer? Prostate. 2013 Mar; 73(4):442-8. PMID: 22949099.
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    18. Ross HM, Kryvenko ON, Cowan JE, Simko JP, Wheeler TM, Epstein JI. Do adenocarcinomas of the prostate with Gleason score (GS) ?6 have the potential to metastasize to lymph nodes? Am J Surg Pathol. 2012 Sep; 36(9):1346-52. PMID: 22531173; PMCID: PMC3421030.
    19. Murphy M, Olivera C, Wheeler T, Casiano E, Siddiqui N, Gala R, Gamble T, Balk EM, Sung VW. Postoperative management and restrictions for female pelvic surgery: a systematic review. Int Urogynecol J. 2013 Feb; 24(2):185-93. PMID: 22872033.
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    20. Wilt TJ, Brawer MK, Jones KM, Barry MJ, Aronson WJ, Fox S, Gingrich JR, Wei JT, Gilhooly P, Grob BM, Nsouli I, Iyer P, Cartagena R, Snider G, Roehrborn C, Sharifi R, Blank W, Pandya P, Andriole GL, Culkin D, Wheeler T. Radical prostatectomy versus observation for localized prostate cancer. N Engl J Med. 2012 Jul 19; 367(3):203-13. PMID: 22808955; PMCID: PMC3429335.
    21. Van Belle S, Swieboda-Sadlej A, Karanikiotis C, Labourey JL, Galid A, Wheeler T, Pujol B, Aerts JG. A final analysis from the CHOICE study examining darbepoetin alfa use for chemotherapy-induced anaemia in current European clinical practice. Curr Med Res Opin. 2012 Jul; 28(7):1079-87. PMID: 22642867.
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    22. Sonpavde G, Thompson TC, Jain RK, Ayala GE, Kurosaka S, Edamura K, Tabata K, Ren C, Goltsov AA, Mims MP, Hayes TG, Ittmann MM, Wheeler TM, Gee A, Miles BJ, Kadmon D. GLIPR1 tumor suppressor gene expressed by adenoviral vector as neoadjuvant intraprostatic injection for localized intermediate or high-risk prostate cancer preceding radical prostatectomy. Clin Cancer Res. 2011 Nov 15; 17(22):7174-82. PMID: 21933889; PMCID: PMC3865786.
    23. Iczkowski KA, Torkko KC, Kotnis GR, Wilson RS, Huang W, Wheeler TM, Abeyta AM, Lucia MS. Pseudolumen size and perimeter in prostate cancer: correlation with patient outcome. Prostate Cancer. 2011; 2011:693853. PMID: 22110997; PMCID: PMC3200296.
    24. Iczkowski KA, Torkko KC, Kotnis GR, Wilson RS, Huang W, Wheeler TM, Abeyta AM, La Rosa FG, Cook S, Werahera PN, Lucia MS. Digital quantification of five high-grade prostate cancer patterns, including the cribriform pattern, and their association with adverse outcome. Am J Clin Pathol. 2011 Jul; 136(1):98-107. PMID: 21685037; PMCID: PMC4656017.
    25. Mouraviev V, Villers A, Bostwick DG, Wheeler TM, Montironi R, Polascik TJ. Understanding the pathological features of focality, grade and tumour volume of early-stage prostate cancer as a foundation for parenchyma-sparing prostate cancer therapies: active surveillance and focal targeted therapy. BJU Int. 2011 Oct; 108(7):1074-85. PMID: 21489116.
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    26. Van Belle S, Karanikiotis C, Labourey JL, Galid A, Wheeler T, Pujol B. Current practice of darbepoetin alfa in the management of haemoglobin levels in cancer patients undergoing chemotherapy - data from the CHOICE study. Curr Med Res Opin. 2011 May; 27(5):987-94. PMID: 21385113.
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    27. Cohen RJ, O'Brien BA, Wheeler TM. Desquamating apoptotic variant of high-grade prostatic intraepithelial neoplasia: a possible precursor of intraductal prostatic carcinoma. Hum Pathol. 2011 Jun; 42(6):892-5. PMID: 21288556.
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    28. Cohen RJ, O'Brien BA, Wheeler TM. Ductal adenocarcinoma of the prostate. Hum Pathol. 2011 Apr; 42(4):605-6; author reply 606-7. PMID: 21237485.
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    29. Ayala GE, Muezzinoglu B, Hammerich KH, Frolov A, Liu H, Scardino PT, Li R, Sayeeduddin M, Ittmann MM, Kadmon D, Miles BJ, Wheeler TM, Rowley DR. Determining prostate cancer-specific death through quantification of stromogenic carcinoma area in prostatectomy specimens. Am J Pathol. 2011 Jan; 178(1):79-87. PMID: 21224046; PMCID: PMC3069909.
    30. Hall CA, Wang R, Miao J, Oliva E, Shen X, Wheeler T, Hilsenbeck SG, Orsulic S, Goode S. Hippo pathway effector Yap is an ovarian cancer oncogene. Cancer Res. 2010 Nov 1; 70(21):8517-25. PMID: 20947521; PMCID: PMC2970655.
    31. Samaratunga H, Montironi R, True L, Epstein JI, Griffiths DF, Humphrey PA, van der Kwast T, Wheeler TM, Srigley JR, Delahunt B, Egevad L. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 1: specimen handling. Mod Pathol. 2011 Jan; 24(1):6-15. PMID: 20834234.
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    32. Berney DM, Wheeler TM, Grignon DJ, Epstein JI, Griffiths DF, Humphrey PA, van der Kwast T, Montironi R, Delahunt B, Egevad L, Srigley JR. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 4: seminal vesicles and lymph nodes. Mod Pathol. 2011 Jan; 24(1):39-47. PMID: 20818343.
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    33. van der Kwast TH, Amin MB, Billis A, Epstein JI, Griffiths D, Humphrey PA, Montironi R, Wheeler TM, Srigley JR, Egevad L, Delahunt B. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 2: T2 substaging and prostate cancer volume. Mod Pathol. 2011 Jan; 24(1):16-25. PMID: 20818340.
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    34. Magi-Galluzzi C, Evans AJ, Delahunt B, Epstein JI, Griffiths DF, van der Kwast TH, Montironi R, Wheeler TM, Srigley JR, Egevad LL, Humphrey PA. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 3: extraprostatic extension, lymphovascular invasion and locally advanced disease. Mod Pathol. 2011 Jan; 24(1):26-38. PMID: 20802467.
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    35. Tan PH, Cheng L, Srigley JR, Griffiths D, Humphrey PA, van der Kwast TH, Montironi R, Wheeler TM, Delahunt B, Egevad L, Epstein JI. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 5: surgical margins. Mod Pathol. 2011 Jan; 24(1):48-57. PMID: 20729812.
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    36. O'Brien BA, Cohen RJ, Wheeler TM, Moorin RE. A post-radical-prostatectomy nomogram incorporating new pathological variables and interaction terms for improved prognosis. BJU Int. 2011 Feb; 107(3):389-95. PMID: 20707795.
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    37. Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taube S, Torlakovic EE, Valenstein P, Viale G, Visscher D, Wheeler T, Williams RB, Wittliff JL, Wolff AC. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer (unabridged version). Arch Pathol Lab Med. 2010 Jul; 134(7):e48-72. PMID: 20586616.
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    38. Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taube S, Torlakovic EE, Valenstein P, Viale G, Visscher D, Wheeler T, Williams RB, Wittliff JL, Wolff AC. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. Arch Pathol Lab Med. 2010 Jun; 134(6):907-22. PMID: 20524868; PMCID: PMC3073033.
    39. Bañez LL, Sun L, van Leenders GJ, Wheeler TM, Bangma CH, Freedland SJ, Ittmann MM, Lark AL, Madden JF, Hartman A, Weiss G, Castaños-Vélez E. Multicenter clinical validation of PITX2 methylation as a prostate specific antigen recurrence predictor in patients with post-radical prostatectomy prostate cancer. J Urol. 2010 Jul; 184(1):149-56. PMID: 20478579.
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    40. Hammond ME, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S, Fitzgibbons PL, Francis G, Goldstein NS, Hayes M, Hicks DG, Lester S, Love R, Mangu PB, McShane L, Miller K, Osborne CK, Paik S, Perlmutter J, Rhodes A, Sasano H, Schwartz JN, Sweep FC, Taube S, Torlakovic EE, Valenstein P, Viale G, Visscher D, Wheeler T, Williams RB, Wittliff JL, Wolff AC. American Society of Clinical Oncology/College Of American Pathologists guideline recommendations for immunohistochemical testing of estrogen and progesterone receptors in breast cancer. J Clin Oncol. 2010 Jun 1; 28(16):2784-95. PMID: 20404251; PMCID: PMC2881855.
    41. McGuire AL, Majumder MA, Halpern SD, Swindell JS, Yaeger LV, Gibbs RA, Wheeler TM. Taking DNA from the dead. Nat Rev Genet. 2010 May; 11(5):318. PMID: 20332774; PMCID: PMC4065415.
    42. Wheeler T. Second opinions in pathology. J Urol. 2010 Mar; 183(3):850-1. PMID: 20089265.
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    43. Srigley JR, Humphrey PA, Amin MB, Chang SS, Egevad L, Epstein JI, Grignon DJ, McKiernan JM, Montironi R, Renshaw AA, Reuter VE, Wheeler TM. Protocol for the examination of specimens from patients with carcinoma of the prostate gland. Arch Pathol Lab Med. 2009 Oct; 133(10):1568-76. PMID: 19792046.
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    44. Li R, Erdamar S, Dai H, Sayeeduddin M, Frolov A, Wheeler TM, Ayala GE. Cytoplasmic accumulation of glycogen synthase kinase-3beta is associated with aggressive clinicopathological features in human prostate cancer. Anticancer Res. 2009 Jun; 29(6):2077-81. PMID: 19528467.
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    45. Li R, Dai H, Wheeler TM, Sayeeduddin M, Scardino PT, Frolov A, Ayala GE. Prognostic value of Akt-1 in human prostate cancer: a computerized quantitative assessment with quantum dot technology. Clin Cancer Res. 2009 May 15; 15(10):3568-73. PMID: 19417030.
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    46. Weinreb JC, Blume JD, Coakley FV, Wheeler TM, Cormack JB, Sotto CK, Cho H, Kawashima A, Tempany-Afdhal CM, Macura KJ, Rosen M, Gerst SR, Kurhanewicz J. Prostate cancer: sextant localization at MR imaging and MR spectroscopic imaging before prostatectomy--results of ACRIN prospective multi-institutional clinicopathologic study. Radiology. 2009 Apr; 251(1):122-33. PMID: 19332850; PMCID: PMC2663583.
    47. DeFrancisco AL, Macdougall IC, Carrera F, Braun J, Bárány P, Bridges I, Wheeler T, Tran D, Dietrich A. Intercurrent events and comorbid conditions influence hemoglobin level variability in dialysis patients. Clin Nephrol. 2009 Apr; 71(4):397-404. PMID: 19356372.
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    48. Weiss G, Cottrell S, Distler J, Schatz P, Kristiansen G, Ittmann M, Haefliger C, Lesche R, Hartmann A, Corman J, Wheeler T. DNA methylation of the PITX2 gene promoter region is a strong independent prognostic marker of biochemical recurrence in patients with prostate cancer after radical prostatectomy. J Urol. 2009 Apr; 181(4):1678-85. PMID: 19233404.
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    49. Sartor AO, Hricak H, Wheeler TM, Coleman J, Penson DF, Carroll PR, Rubin MA, Scardino PT. Evaluating localized prostate cancer and identifying candidates for focal therapy. Urology. 2008 Dec; 72(6 Suppl):S12-24. PMID: 19095124.
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    50. Ayala GE, Dai H, Powell M, Li R, Ding Y, Wheeler TM, Shine D, Kadmon D, Thompson T, Miles BJ, Ittmann MM, Rowley D. Cancer-related axonogenesis and neurogenesis in prostate cancer. Clin Cancer Res. 2008 Dec 1; 14(23):7593-603. PMID: 19047084.
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    51. Ayala G, Yan J, Li R, Ding Y, Thompson TC, Mims MP, Hayes TG, MacDonnell V, Lynch RG, Frolov A, Miles BJ, Wheeler TM, Harper JW, Tsai MJ, Ittmann MM, Kadmon D. Bortezomib-mediated inhibition of steroid receptor coactivator-3 degradation leads to activated Akt. Clin Cancer Res. 2008 Nov 15; 14(22):7511-8. PMID: 19010869; PMCID: PMC2820291.
    52. Evans AJ, Henry PC, Van der Kwast TH, Tkachuk DC, Watson K, Lockwood GA, Fleshner NE, Cheung C, Belanger EC, Amin MB, Boccon-Gibod L, Bostwick DG, Egevad L, Epstein JI, Grignon DJ, Jones EC, Montironi R, Moussa M, Sweet JM, Trpkov K, Wheeler TM, Srigley JR. Interobserver variability between expert urologic pathologists for extraprostatic extension and surgical margin status in radical prostatectomy specimens. Am J Surg Pathol. 2008 Oct; 32(10):1503-12. PMID: 18708939.
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    53. Goldsmith JD, Siegal GP, Suster S, Wheeler TM, Brown RW. Reporting guidelines for clinical laboratory reports in surgical pathology. Arch Pathol Lab Med. 2008 Oct; 132(10):1608-16. PMID: 18834219.
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    54. Latour M, Amin MB, Billis A, Egevad L, Grignon DJ, Humphrey PA, Reuter VE, Sakr WA, Srigley JR, Wheeler TM, Yang XJ, Epstein JI. Grading of invasive cribriform carcinoma on prostate needle biopsy: an interobserver study among experts in genitourinary pathology. Am J Surg Pathol. 2008 Oct; 32(10):1532-9. PMID: 18724248.
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    55. Fitzgerald MP, Lemack G, Wheeler T, Litman HJ. Nocturia, nocturnal incontinence prevalence, and response to anticholinergic and behavioral therapy. Int Urogynecol J Pelvic Floor Dysfunct. 2008 Nov; 19(11):1545-50. PMID: 18704249; PMCID: PMC3691384.
    56. Swindle P, Eastham JA, Ohori M, Kattan MW, Wheeler T, Maru N, Slawin K, Scardino PT. Do margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol. 2008 May; 179(5 Suppl):S47-51. PMID: 18405751.
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    57. Cohen RJ, Shannon BA, Phillips M, Moorin RE, Wheeler TM, Garrett KL. Central zone carcinoma of the prostate gland: a distinct tumor type with poor prognostic features. J Urol. 2008 May; 179(5):1762-7; discussion 1767. PMID: 18343454.
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    58. Hammerich KH, Hille S, Ayala GE, Wheeler TM, Engers R, Ackermann R, Mueller-Mattheis V. Malignant advanced granulosa cell tumor of the adult testis: case report and review of the literature. Hum Pathol. 2008 May; 39(5):701-9. PMID: 18304605.
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    59. Hammerich KH, Ayala GE, Ayala GA, Wheeler TM. Application of immunohistochemistry to the genitourinary system (prostate, urinary bladder, testis, and kidney). Arch Pathol Lab Med. 2008 Mar; 132(3):432-40. PMID: 18318585.
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    60. Iczkowski KA, Hossain D, Torkko KC, Qian J, Lucia MS, Wheeler TM, Rewcastle JC, Bostwick DG. Preoperative prediction of unifocal, unilateral, margin-negative, and small volume prostate cancer. Urology. 2008 Jun; 71(6):1166-71. PMID: 18279927.
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    61. Yanagisawa N, Li R, Rowley D, Liu H, Kadmon D, Miles BJ, Wheeler TM, Ayala GE. Reprint of: Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy. Hum Pathol. 2008 Feb; 39(2):282-91. PMID: 18206496.
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    62. Haigh B, Hood K, Broadhurst M, Medele S, Callaghan M, Smolenski G, Dines M, Wheeler T. The bovine salivary proteins BSP30a and BSP30b are independently expressed BPI-like proteins with anti-Pseudomonas activity. Mol Immunol. 2008 Apr; 45(7):1944-51. PMID: 18055015.
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    63. Kiniwa Y, Miyahara Y, Wang HY, Peng W, Peng G, Wheeler TM, Thompson TC, Old LJ, Wang RF. CD8+ Foxp3+ regulatory T cells mediate immunosuppression in prostate cancer. Clin Cancer Res. 2007 Dec 1; 13(23):6947-58. PMID: 18056169.
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    64. Eastham JA, Kuroiwa K, Ohori M, Serio AM, Gorbonos A, Maru N, Vickers AJ, Slawin KM, Wheeler TM, Reuter VE, Scardino PT. Prognostic significance of location of positive margins in radical prostatectomy specimens. Urology. 2007 Nov; 70(5):965-9. PMID: 18068455.
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    65. Eggener SE, Scardino PT, Carroll PR, Zelefsky MJ, Sartor O, Hricak H, Wheeler TM, Fine SW, Trachtenberg J, Rubin MA, Ohori M, Kuroiwa K, Rossignol M, Abenhaim L. Focal therapy for localized prostate cancer: a critical appraisal of rationale and modalities. J Urol. 2007 Dec; 178(6):2260-7. PMID: 17936815.
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    66. Yanagisawa N, Li R, Rowley D, Liu H, Kadmon D, Miles BJ, Wheeler TM, Ayala GE. Stromogenic prostatic carcinoma pattern (carcinomas with reactive stromal grade 3) in needle biopsies predicts biochemical recurrence-free survival in patients after radical prostatectomy. Hum Pathol. 2007 Nov; 38(11):1611-20. PMID: 17868773.
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    67. Ishii J, Ohori M, Scardino P, Tsuboi T, Slawin K, Wheeler T. Significance of the craniocaudal distribution of cancer in radical prostatectomy specimens. Int J Urol. 2007 Sep; 14(9):817-21. PMID: 17760748.
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    68. Yang G, Addai J, Wheeler TM, Frolov A, Miles BJ, Kadmon D, Thompson TC. Correlative evidence that prostate cancer cell-derived caveolin-1 mediates angiogenesis. Hum Pathol. 2007 Nov; 38(11):1688-95. PMID: 17707459.
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    69. Cordon-Cardo C, Kotsianti A, Verbel DA, Teverovskiy M, Capodieci P, Hamann S, Jeffers Y, Clayton M, Elkhettabi F, Khan FM, Sapir M, Bayer-Zubek V, Vengrenyuk Y, Fogarsi S, Saidi O, Reuter VE, Scher HI, Kattan MW, Bianco FJ, Wheeler TM, Ayala GE, Scardino PT, Donovan MJ. Improved prediction of prostate cancer recurrence through systems pathology. J Clin Invest. 2007 Jul; 117(7):1876-83. PMID: 17557117; PMCID: PMC1884691.
    70. Cohen RJ, Wheeler TM, Bonkhoff H, Rubin MA. A proposal on the identification, histologic reporting, and implications of intraductal prostatic carcinoma. Arch Pathol Lab Med. 2007 Jul; 131(7):1103-9. PMID: 17616999.
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    71. Kwabi-Addo B, Chung W, Shen L, Ittmann M, Wheeler T, Jelinek J, Issa JP. Age-related DNA methylation changes in normal human prostate tissues. Clin Cancer Res. 2007 Jul 1; 13(13):3796-802. PMID: 17606710.
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    72. Li R, Erdamar S, Dai H, Wheeler TM, Frolov A, Scardino PT, Thompson TC, Ayala GE. Forkhead protein FKHR and its phosphorylated form p-FKHR in human prostate cancer. Hum Pathol. 2007 Oct; 38(10):1501-7. PMID: 17597184; PMCID: PMC2646886.
    73. Wheeler TM, Krym MC, Thornton CA. Ribonuclear foci at the neuromuscular junction in myotonic dystrophy type 1. Neuromuscul Disord. 2007 Mar; 17(3):242-7. PMID: 17306536; PMCID: PMC2752326.
    74. Shariat SF, Roehrborn CG, McConnell JD, Park S, Alam N, Wheeler TM, Slawin KM. Association of the circulating levels of the urokinase system of plasminogen activation with the presence of prostate cancer and invasion, progression, and metastasis. J Clin Oncol. 2007 Feb 1; 25(4):349-55. PMID: 17264329.
      View in: PubMed
    75. Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, Dowsett M, Fitzgibbons PL, Hanna WM, Langer A, McShane LM, Paik S, Pegram MD, Perez EA, Press MF, Rhodes A, Sturgeon C, Taube SE, Tubbs R, Vance GH, van de Vijver M, Wheeler TM, Hayes DF. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. Arch Pathol Lab Med. 2007; 131(1):18-43. PMID: 19548375.
      View in: PubMed
    76. Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, Dowsett M, Fitzgibbons PL, Hanna WM, Langer A, McShane LM, Paik S, Pegram MD, Perez EA, Press MF, Rhodes A, Sturgeon C, Taube SE, Tubbs R, Vance GH, van de Vijver M, Wheeler TM, Hayes DF. American Society of Clinical Oncology/College of American Pathologists guideline recommendations for human epidermal growth factor receptor 2 testing in breast cancer. J Clin Oncol. 2007 Jan 1; 25(1):118-45. PMID: 17159189.
      View in: PubMed
    77. Hammerich KH, Slawin KM, Wheeler TM. Prognostic indicators for disease progression following radical prostatectomy. Nat Clin Pract Urol. 2006 Dec; 3(12):638-9. PMID: 17149379.
      View in: PubMed
    78. Dai H, Li R, Wheeler T, Ozen M, Ittmann M, Anderson M, Wang Y, Rowley D, Younes M, Ayala GE. Enhanced survival in perineural invasion of pancreatic cancer: an in vitro approach. Hum Pathol. 2007 Feb; 38(2):299-307. PMID: 17097719.
      View in: PubMed
    79. Donohue JF, Bianco FJ, Kuroiwa K, Vickers AJ, Wheeler TM, Scardino PT, Reuter VA, Eastham JA. Poorly differentiated prostate cancer treated with radical prostatectomy: long-term outcome and incidence of pathological downgrading. J Urol. 2006 Sep; 176(3):991-5. PMID: 16890678; PMCID: PMC2239297.
    80. Tahir SA, Frolov A, Hayes TG, Mims MP, Miles BJ, Lerner SP, Wheeler TM, Ayala G, Thompson TC, Kadmon D. Preoperative serum caveolin-1 as a prognostic marker for recurrence in a radical prostatectomy cohort. Clin Cancer Res. 2006 Aug 15; 12(16):4872-5. PMID: 16914574.
      View in: PubMed
    81. Srigley JR, Amin MB, Epstein JI, Grignon DJ, Humphrey PA, Renshaw AA, Wheeler TM. Updated protocol for the examination of specimens from patients with carcinomas of the prostate gland. Arch Pathol Lab Med. 2006 Jul; 130(7):936-46. PMID: 16831046.
      View in: PubMed
    82. Shen SS, Lerner SP, Muezzinoglu B, Truong LD, Amiel G, Wheeler TM. Prostatic involvement by transitional cell carcinoma in patients with bladder cancer and its prognostic significance. Hum Pathol. 2006 Jun; 37(6):726-34. PMID: 16733214.
      View in: PubMed
    83. Secin FP, Bianco FJ, Vickers AJ, Reuter V, Wheeler T, Fearn PA, Eastham JA, Scardino PT. Cancer-specific survival and predictors of prostate-specific antigen recurrence and survival in patients with seminal vesicle invasion after radical prostatectomy. Cancer. 2006 Jun 1; 106(11):2369-75. PMID: 16649221.
      View in: PubMed
    84. Ayala GE, Dai H, Tahir SA, Li R, Timme T, Ittmann M, Frolov A, Wheeler TM, Rowley D, Thompson TC. Stromal antiapoptotic paracrine loop in perineural invasion of prostatic carcinoma. Cancer Res. 2006 May 15; 66(10):5159-64. PMID: 16707439.
      View in: PubMed
    85. Lopez-Corona E, Ohori M, Wheeler TM, Reuter VE, Scardino PT, Kattan MW, Eastham JA. Prostate cancer diagnosed after repeat biopsies have a favorable pathological outcome but similar recurrence rate. J Urol. 2006 Mar; 175(3 Pt 1):923-7; discussion 927-8. PMID: 16469581; PMCID: PMC1951512.
    86. Ayala G, Satoh T, Li R, Shalev M, Gdor Y, Aguilar-Cordova E, Frolov A, Wheeler TM, Miles BJ, Rauen K, Teh BS, Butler EB, Thompson TC, Kadmon D. Biological response determinants in HSV-tk + ganciclovir gene therapy for prostate cancer. Mol Ther. 2006 Apr; 13(4):716-28. PMID: 16480930.
      View in: PubMed
    87. Ayala GE, Dai H, Li R, Ittmann M, Thompson TC, Rowley D, Wheeler TM. Bystin in perineural invasion of prostate cancer. Prostate. 2006 Feb 15; 66(3):266-72. PMID: 16245277.
      View in: PubMed
    88. Mims MP, Hayes TG, Zheng S, Leal SM, Frolov A, Ittmann MM, Wheeler TM, Prchal JT. Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women. Cancer Res. 2006 Feb 1; 66(3):1880; author reply 1880-1. PMID: 16452251.
      View in: PubMed
    89. Li R, Wheeler TM, Dai H, Sayeeduddin M, Scardino PT, Frolov A, Ayala GE. Biological correlates of p27 compartmental expression in prostate cancer. J Urol. 2006 Feb; 175(2):528-32. PMID: 16406988.
      View in: PubMed
    90. Tetzlaff MT, Teh BS, Timme TL, Fujita T, Satoh T, Tabata K, Mai WY, Vlachaki MT, Amato RJ, Kadmon D, Miles BJ, Ayala G, Wheeler TM, Aguilar-Cordova E, Thompson TC, Butler EB. Expanding the therapeutic index of radiation therapy by combining in situ gene therapy in the treatment of prostate cancer. Technol Cancer Res Treat. 2006 Feb; 5(1):23-36. PMID: 16417399.
      View in: PubMed
    91. Malins DC, Gilman NK, Green VM, Wheeler TM, Barker EA, Anderson KM. A cancer DNA phenotype in healthy prostates, conserved in tumors and adjacent normal cells, implies a relationship to carcinogenesis. Proc Natl Acad Sci U S A. 2005 Dec 27; 102(52):19093-6. PMID: 16361440; PMCID: PMC1323211.
    92. Anton RC, Wheeler TM. Frozen section of thyroid and parathyroid specimens. Arch Pathol Lab Med. 2005 Dec; 129(12):1575-84. PMID: 16329730.
      View in: PubMed
    93. Dai H, Li R, Wheeler T, Diaz de Vivar A, Frolov A, Tahir S, Agoulnik I, Thompson T, Rowley D, Ayala G. Pim-2 upregulation: biological implications associated with disease progression and perinueral invasion in prostate cancer. Prostate. 2005 Nov 1; 65(3):276-86. PMID: 16015593.
      View in: PubMed
    94. Haqq C, Li R, Khodabakhsh D, Frolov A, Ginzinger D, Thompson T, Wheeler T, Carroll P, Ayala G. Ethnic and racial differences in prostate stromal estrogen receptor alpha. Prostate. 2005 Oct 1; 65(2):101-9. PMID: 15880569.
      View in: PubMed
    95. Powell MS, Li R, Dai H, Sayeeduddin M, Wheeler TM, Ayala GE. Neuroanatomy of the normal prostate. Prostate. 2005 Sep 15; 65(1):52-7. PMID: 15806576.
      View in: PubMed
    96. Ramasubbu K, Wheeler TM, Reardon MJ, Dokainish H. Visceral pericardial hemangioma: unusual location for a rare cardiac tumor. J Am Soc Echocardiogr. 2005 Sep; 18(9):981. PMID: 16153530.
      View in: PubMed
    97. Swindle P, Eastham JA, Ohori M, Kattan MW, Wheeler T, Maru N, Slawin K, Scardino PT. Do margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol. 2005 Sep; 174(3):903-7. PMID: 16093984.
      View in: PubMed
    98. Srigley JR, Amin M, Boccon-Gibod L, Egevad L, Epstein JI, Humphrey PA, Mikuz G, Newling D, Nilsson S, Sakr W, Wheeler TM, Montironi R. Prognostic and predictive factors in prostate cancer: historical perspectives and recent international consensus initiatives. Scand J Urol Nephrol Suppl. 2005 May; (216):8-19. PMID: 16019756.
      View in: PubMed
    99. Epstein JI, Amin M, Boccon-Gibod L, Egevad L, Humphrey PA, Mikuz G, Newling D, Nilsson S, Sakr W, Srigley JR, Wheeler TM, Montironi R. Prognostic factors and reporting of prostate carcinoma in radical prostatectomy and pelvic lymphadenectomy specimens. Scand J Urol Nephrol Suppl. 2005 May; (216):34-63. PMID: 16019758.
      View in: PubMed
    100. Amin M, Boccon-Gibod L, Egevad L, Epstein JI, Humphrey PA, Mikuz G, Newling D, Nilsson S, Sakr W, Srigley JR, Wheeler TM, Montironi R. Prognostic and predictive factors and reporting of prostate carcinoma in prostate needle biopsy specimens. Scand J Urol Nephrol Suppl. 2005 May; (216):20-33. PMID: 16019757.
      View in: PubMed
    101. Amrikachi M, Ponder TB, Wheeler TM, Smith D, Ramzy I. Thyroid fine-needle aspiration biopsy in children and adolescents: experience with 218 aspirates. Diagn Cytopathol. 2005 Apr; 32(4):189-92. PMID: 15754376.
      View in: PubMed
    102. Yang G, Timme TL, Frolov A, Wheeler TM, Thompson TC. Combined c-Myc and caveolin-1 expression in human prostate carcinoma predicts prostate carcinoma progression. Cancer. 2005 Mar 15; 103(6):1186-94. PMID: 15712208.
      View in: PubMed
    103. Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC. The emerging role of the PI3-K-Akt pathway in prostate cancer progression. Prostate Cancer Prostatic Dis. 2005; 8(2):108-18. PMID: 15724144.
      View in: PubMed
    104. Kamat AA, Younes PS, Sayeeduddin M, Wheeler TM, Simpson JL, Agoulnik AI. Protein expression profiling of endometriosis: validation of 2-mm tissue microarrays. Fertil Steril. 2004 Dec; 82(6):1681-3. PMID: 15589880.
      View in: PubMed
    105. Ayala G, Thompson T, Yang G, Frolov A, Li R, Scardino P, Ohori M, Wheeler T, Harper W. High levels of phosphorylated form of Akt-1 in prostate cancer and non-neoplastic prostate tissues are strong predictors of biochemical recurrence. Clin Cancer Res. 2004 Oct 1; 10(19):6572-8. PMID: 15475446.
      View in: PubMed
    106. McAlhany SJ, Ayala GE, Frolov A, Ressler SJ, Wheeler TM, Watson JE, Collins C, Rowley DR. Decreased stromal expression and increased epithelial expression of WFDC1/ps20 in prostate cancer is associated with reduced recurrence-free survival. Prostate. 2004 Oct 1; 61(2):182-91. PMID: 15305341.
      View in: PubMed
    107. Canto EI, Singh H, Shariat SF, Kadmon D, Miles BJ, Wheeler TM, Slawin KM. Effects of systematic 12-core biopsy on the performance of percent free prostate specific antigen for prostate cancer detection. J Urol. 2004 Sep; 172(3):900-4. PMID: 15310993.
      View in: PubMed
    108. Ayala GE, Dai H, Ittmann M, Li R, Powell M, Frolov A, Wheeler TM, Thompson TC, Rowley D. Growth and survival mechanisms associated with perineural invasion in prostate cancer. Cancer Res. 2004 Sep 1; 64(17):6082-90. PMID: 15342391.
      View in: PubMed
    109. Kikuchi E, Scardino PT, Wheeler TM, Slawin KM, Ohori M. Is tumor volume an independent prognostic factor in clinically localized prostate cancer? J Urol. 2004 Aug; 172(2):508-11. PMID: 15247716.
      View in: PubMed
    110. Malins DC, Gilman NK, Green VM, Wheeler TM, Barker EA, Vinson MA, Sayeeduddin M, Hellström KE, Anderson KM. Metastatic cancer DNA phenotype identified in normal tissues surrounding metastasizing prostate carcinomas. Proc Natl Acad Sci U S A. 2004 Aug 3; 101(31):11428-31. PMID: 15280533; PMCID: PMC509217.
    111. Li R, Wheeler T, Dai H, Frolov A, Thompson T, Ayala G. High level of androgen receptor is associated with aggressive clinicopathologic features and decreased biochemical recurrence-free survival in prostate: cancer patients treated with radical prostatectomy. Am J Surg Pathol. 2004 Jul; 28(7):928-34. PMID: 15223964.
      View in: PubMed
    112. Adler HL, Haddad JL, Wheeler TM, Kim ED. Intratesticular adenomatoid tumor radiographically mimicking a primary testicular malignancy. ScientificWorldJournal. 2004 Jun 7; 4 Suppl 1:11-5. PMID: 15349521.
      View in: PubMed
    113. Satoh T, Teh BS, Timme TL, Mai WY, Gdor Y, Kusaka N, Fujita T, Pramudji CK, Vlachaki MT, Ayala G, Wheeler T, Amato R, Miles BJ, Kadmon D, Butler EB, Thompson TC. Enhanced systemic T-cell activation after in situ gene therapy with radiotherapy in prostate cancer patients. Int J Radiat Oncol Biol Phys. 2004 Jun 1; 59(2):562-71. PMID: 15145177.
      View in: PubMed
    114. Shariat SF, Menesses-Diaz A, Kim IY, Muramoto M, Wheeler TM, Slawin KM. Tissue expression of transforming growth factor-beta1 and its receptors: correlation with pathologic features and biochemical progression in patients undergoing radical prostatectomy. Urology. 2004 Jun; 63(6):1191-7. PMID: 15183988.
      View in: PubMed
    115. Singh H, Canto EI, Shariat SF, Kadmon D, Miles BJ, Wheeler TM, Slawin KM. Predictors of prostate cancer after initial negative systematic 12 core biopsy. J Urol. 2004 May; 171(5):1850-4. PMID: 15076292.
      View in: PubMed
    116. Shariat SF, Anwuri VA, Lamb DJ, Shah NV, Wheeler TM, Slawin KM. Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy. J Clin Oncol. 2004 May 1; 22(9):1655-63. PMID: 15117988.
      View in: PubMed
    117. Ohori M, Kattan MW, Koh H, Maru N, Slawin KM, Shariat S, Muramoto M, Reuter VE, Wheeler TM, Scardino PT. Predicting the presence and side of extracapsular extension: a nomogram for staging prostate cancer. J Urol. 2004 May; 171(5):1844-9; discussion 1849. PMID: 15076291.
      View in: PubMed
    118. Teh BS, Ayala G, Aguilar L, Mai WY, Timme TL, Vlachaki MT, Miles B, Kadmon D, Wheeler T, Caillouet J, Davis M, Carpenter LS, Lu HH, Chiu JK, Woo SY, Thompson T, Aguilar-Cordova E, Butler EB. Phase I-II trial evaluating combined intensity-modulated radiotherapy and in situ gene therapy with or without hormonal therapy in treatment of prostate cancer-interim report on PSA response and biopsy data. Int J Radiat Oncol Biol Phys. 2004 Apr 1; 58(5):1520-9. PMID: 15050332.
      View in: PubMed
    119. Patel MI, DeConcini DT, Lopez-Corona E, Ohori M, Wheeler T, Scardino PT. An analysis of men with clinically localized prostate cancer who deferred definitive therapy. J Urol. 2004 Apr; 171(4):1520-4. PMID: 15017211.
      View in: PubMed
    120. Shariat SF, Kattan MW, Traxel E, Andrews B, Zhu K, Wheeler TM, Slawin KM. Association of pre- and postoperative plasma levels of transforming growth factor beta(1) and interleukin 6 and its soluble receptor with prostate cancer progression. Clin Cancer Res. 2004 Mar 15; 10(6):1992-9. PMID: 15041717.
      View in: PubMed
    121. Yang G, Addai J, Tian WH, Frolov A, Wheeler TM, Thompson TC. Reduced infiltration of class A scavenger receptor positive antigen-presenting cells is associated with prostate cancer progression. Cancer Res. 2004 Mar 15; 64(6):2076-82. PMID: 15026346.
      View in: PubMed
    122. Singh H, Canto EI, Shariat SF, Kadmon D, Miles BJ, Wheeler TM, Slawin KM. Improved detection of clinically significant, curable prostate cancer with systematic 12-core biopsy. J Urol. 2004 Mar; 171(3):1089-92. PMID: 14767277.
      View in: PubMed
    123. Ohori M, Kattan M, Scardino PT, Wheeler TM. Radical prostatectomy for carcinoma of the prostate. Mod Pathol. 2004 Mar; 17(3):349-59. PMID: 14765206.
      View in: PubMed
    124. Eid W, Wheeler TM, Sharma MD. Recurrent hypercalcemia due to ectopic production of parathyroid hormone-related protein and intact parathyroid hormone in a single patient with multiple malignancies. Endocr Pract. 2004 Mar-Apr; 10(2):125-8. PMID: 15256329.
      View in: PubMed
    125. Li R, Younes M, Wheeler TM, Scardino P, Ohori M, Frolov A, Ayala G. Expression of vascular endothelial growth factor receptor-3 (VEGFR-3) in human prostate. Prostate. 2004 Feb 1; 58(2):193-9. PMID: 14716745.
      View in: PubMed
    126. Cagiannos I, Karakiewicz P, Graefen M, Eastham JA, Ohori M, Rabbani F, Reuter V, Wheeler T, Kupelian P, Klein E, Huland H, Hammerer PG, Erbersdobler A, Schroeder F, Wildhagen M, Quinn DI, Henshall SM, Grygiel JJ, Sutherland RL, Stricker PD, Morash CG, Scardino PT, Kattan MW. Is year of radical prostatectomy a predictor of outcome in prostate cancer? J Urol. 2004 Feb; 171(2 Pt 1):692-6. PMID: 14713788.
      View in: PubMed
    127. Graefen M, Ohori M, Karakiewicz PI, Cagiannos I, Hammerer PG, Haese A, Erbersdobler A, Henke RP, Huland H, Wheeler TM, Slawin K, Scardino PT, Kattan MW. Assessment of the enhancement in predictive accuracy provided by systematic biopsy in predicting outcome for clinically localized prostate cancer. J Urol. 2004 Jan; 171(1):200-3. PMID: 14665876.
      View in: PubMed
    128. Singh H, Canto EI, Shariat SF, Kadmon D, Miles BJ, Wheeler TM, Slawin KM. Six additional systematic lateral cores enhance sextant biopsy prediction of pathological features at radical prostatectomy. J Urol. 2004 Jan; 171(1):204-9. PMID: 14665877.
      View in: PubMed
    129. Matsumoto K, Shariat SF, Casella R, Wheeler TM, Slawin KM, Lerner SP. Preoperative plasma soluble E-cadherin predicts metastases to lymph nodes and prognosis in patients undergoing radical cystectomy. J Urol. 2003 Dec; 170(6 Pt 1):2248-52. PMID: 14634390.
      View in: PubMed
    130. Eastham JA, Kattan MW, Riedel E, Begg CB, Wheeler TM, Gerigk C, Gonen M, Reuter V, Scardino PT. Variations among individual surgeons in the rate of positive surgical margins in radical prostatectomy specimens. J Urol. 2003 Dec; 170(6 Pt 1):2292-5. PMID: 14634399.
      View in: PubMed
    131. Teh BS, Bastasch MD, Mai WY, Butler EB, Wheeler TM. Predictors of extracapsular extension and its radial distance in prostate cancer: implications for prostate IMRT, brachytherapy, and surgery. Cancer J. 2003 Nov-Dec; 9(6):454-60. PMID: 14740973.
      View in: PubMed
    132. Kattan MW, Eastham JA, Wheeler TM, Maru N, Scardino PT, Erbersdobler A, Graefen M, Huland H, Koh H, Shariat S, Slawin KM, Ohori M. Counseling men with prostate cancer: a nomogram for predicting the presence of small, moderately differentiated, confined tumors. J Urol. 2003 Nov; 170(5):1792-7. PMID: 14532778.
      View in: PubMed
    133. Ayala G, Tuxhorn JA, Wheeler TM, Frolov A, Scardino PT, Ohori M, Wheeler M, Spitler J, Rowley DR. Reactive stroma as a predictor of biochemical-free recurrence in prostate cancer. Clin Cancer Res. 2003 Oct 15; 9(13):4792-801. PMID: 14581350.
      View in: PubMed
    134. Koh H, Kattan MW, Scardino PT, Suyama K, Maru N, Slawin K, Wheeler TM, Ohori M. A nomogram to predict seminal vesicle invasion by the extent and location of cancer in systematic biopsy results. J Urol. 2003 Oct; 170(4 Pt 1):1203-8. PMID: 14501725.
      View in: PubMed
    135. Ayala G, Wang D, Wulf G, Frolov A, Li R, Sowadski J, Wheeler TM, Lu KP, Bao L. The prolyl isomerase Pin1 is a novel prognostic marker in human prostate cancer. Cancer Res. 2003 Oct 1; 63(19):6244-51. PMID: 14559810.
      View in: PubMed
    136. Shariat SF, Kattan MW, Song W, Bernard D, Gottenger E, Wheeler TM, Slawin KM. Early postoperative peripheral blood reverse transcription PCR assay for prostate-specific antigen is associated with prostate cancer progression in patients undergoing radical prostatectomy. Cancer Res. 2003 Sep 15; 63(18):5874-8. PMID: 14522912.
      View in: PubMed
    137. Tahir SA, Ren C, Timme TL, Gdor Y, Hoogeveen R, Morrisett JD, Frolov A, Ayala G, Wheeler TM, Thompson TC. Development of an immunoassay for serum caveolin-1: a novel biomarker for prostate cancer. Clin Cancer Res. 2003 Sep 1; 9(10 Pt 1):3653-9. PMID: 14506154.
      View in: PubMed
    138. Kattan MW, Shariat SF, Andrews B, Zhu K, Canto E, Matsumoto K, Muramoto M, Scardino PT, Ohori M, Wheeler TM, Slawin KM. The addition of interleukin-6 soluble receptor and transforming growth factor beta1 improves a preoperative nomogram for predicting biochemical progression in patients with clinically localized prostate cancer. J Clin Oncol. 2003 Oct 1; 21(19):3573-9. PMID: 12913106.
      View in: PubMed
    139. Shariat SF, Roudier MP, Wilcox GE, Kattan MW, Scardino PT, Vessella RL, Erdamar S, Nguyen C, Wheeler TM, Slawin KM. Comparison of immunohistochemistry with reverse transcription-PCR for the detection of micrometastatic prostate cancer in lymph nodes. Cancer Res. 2003 Aug 1; 63(15):4662-70. PMID: 12907647.
      View in: PubMed
    140. Krouskop TA, Younes PS, Srinivasan S, Wheeler T, Ophir J. Differences in the compressive stress-strain response of infiltrating ductal carcinomas with and without lobular features--implications for mammography and elastography. Ultrason Imaging. 2003 Jul; 25(3):162-70. PMID: 14870801.
      View in: PubMed
    141. Li R, Younes M, Frolov A, Wheeler TM, Scardino P, Ohori M, Ayala G. Expression of neutral amino acid transporter ASCT2 in human prostate. Anticancer Res. 2003 Jul-Aug; 23(4):3413-8. PMID: 12926082.
      View in: PubMed
    142. Shariat SF, Monoski MA, Andrews B, Wheeler TM, Lerner SP, Slawin KM. Association of plasma urokinase-type plasminogen activator and its receptor with clinical outcome in patients undergoing radical cystectomy for transitional cell carcinoma of the bladder. Urology. 2003 May; 61(5):1053-8. PMID: 12736046.
      View in: PubMed
    143. Li R, Wheeler T, Dai H, Ayala G. Neural cell adhesion molecule is upregulated in nerves with prostate cancer invasion. Hum Pathol. 2003 May; 34(5):457-61. PMID: 12792919.
      View in: PubMed
    144. Teh BS, Bastasch MD, Wheeler TM, Mai WY, Frolov A, Uhl BM, Lu HH, Carpenter LS, Chiu JK, McGary J, Woo SY, Grant WH, Butler EB. IMRT for prostate cancer: defining target volume based on correlated pathologic volume of disease. Int J Radiat Oncol Biol Phys. 2003 May 1; 56(1):184-91. PMID: 12694837.
      View in: PubMed
    145. Malins DC, Johnson PM, Barker EA, Polissar NL, Wheeler TM, Anderson KM. Cancer-related changes in prostate DNA as men age and early identification of metastasis in primary prostate tumors. Proc Natl Acad Sci U S A. 2003 Apr 29; 100(9):5401-6. PMID: 12702759; PMCID: PMC154357.
    146. Cornell RJ, Rowley D, Wheeler T, Ali N, Ayala G. Neuroepithelial interactions in prostate cancer are enhanced in the presence ofprostatic stroma. Urology. 2003 Apr; 61(4):870-5. PMID: 12670591.
      View in: PubMed
    147. Shariat SF, Kattan MW, Erdamar S, Nguyen C, Scardino PT, Spencer DM, Wheeler TM, Slawin KM. Detection of clinically significant, occult prostate cancer metastases in lymph nodes using a splice variant-specific rt-PCR assay for human glandular kallikrein. J Clin Oncol. 2003 Apr 1; 21(7):1223-31. PMID: 12663708.
      View in: PubMed
    148. Shariat SF, Kim JH, Ayala GE, Kho K, Wheeler TM, Lerner SP. Cyclooxygenase-2 is highly expressed in carcinoma in situ and T1 transitional cell carcinoma of the bladder. J Urol. 2003 Mar; 169(3):938-42. PMID: 12576817.
      View in: PubMed
    149. Ohori M, Kattan MW, Utsunomiya T, Suyama K, Scardino PT, Wheeler TM. Do impalpable stage T1c prostate cancers visible on ultrasound differ from those not visible? J Urol. 2003 Mar; 169(3):964-8. PMID: 12576823.
      View in: PubMed
    150. Shariat SF, Kim J, Nguyen C, Wheeler TM, Lerner SP, Slawin KM. Correlation of preoperative levels of IGF-I and IGFBP-3 with pathologic parameters and clinical outcome in patients with bladder cancer. Urology. 2003 Feb; 61(2):359-64. PMID: 12597948.
      View in: PubMed
    151. Brophy B, Smolenski G, Wheeler T, Wells D, L'Huillier P, Laible G. Cloned transgenic cattle produce milk with higher levels of beta-casein and kappa-casein. Nat Biotechnol. 2003 Feb; 21(2):157-62. PMID: 12548290.
      View in: PubMed
    152. Lash GE, Taylor CM, Trew AJ, Cooper S, Anthony FW, Wheeler T, Baker PN. Vascular endothelial growth factor and placental growth factor release in cultured trophoblast cells under different oxygen tensions. Growth Factors. 2002 Dec; 20(4):189-96. PMID: 12708795.
      View in: PubMed
    153. Yossepowitch O, Sircar K, Scardino PT, Ohori M, Kattan MW, Wheeler TM, Reuter VE. Bladder neck involvement in pathological stage pT4 radical prostatectomy specimens is not an independent prognostic factor. J Urol. 2002 Nov; 168(5):2011-5. PMID: 12394697.
      View in: PubMed
    154. Yang G, Ayala G, De Marzo A, Tian W, Frolov A, Wheeler TM, Thompson TC, Harper JW. Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival. Clin Cancer Res. 2002 Nov; 8(11):3419-26. PMID: 12429629.
      View in: PubMed
    155. Shariat SF, Gottenger E, Nguyen C, Song W, Kattan MW, Andenoro J, Wheeler TM, Spencer DM, Slawin KM. Preoperative blood reverse transcriptase-PCR assays for prostate-specific antigen and human glandular kallikrein for prediction of prostate cancer progression after radical prostatectomy. Cancer Res. 2002 Oct 15; 62(20):5974-9. PMID: 12384565.
      View in: PubMed
    156. Mouraviev V, Li L, Tahir SA, Yang G, Timme TM, Goltsov A, Ren C, Satoh T, Wheeler TM, Ittmann MM, Miles BJ, Amato RJ, Kadmon D, Thompson TC. The role of caveolin-1 in androgen insensitive prostate cancer. J Urol. 2002 Oct; 168(4 Pt 1):1589-96. PMID: 12352463.
      View in: PubMed
    157. Wu SL, Kothari P, Wheeler TM, Reese T, Connelly JH. Cytokeratins 7 and 20 immunoreactivity in chromophobe renal cell carcinomas and renal oncocytomas. Mod Pathol. 2002 Jul; 15(7):712-7. PMID: 12118108.
      View in: PubMed
    158. Koh H, Maru N, Muramoto M, Wheeler TM, Scardino PT, Ohori M. [The 1992 TNM classification of T2 prostate cancer predicts pathologic stage and prognosis better than the revised 1997 classification]. Nihon Hinyokika Gakkai Zasshi. 2002 Jul; 93(5):595-601. PMID: 12174634.
      View in: PubMed
    159. Cagiannos I, Graefen M, Karakiewicz PI, Ohori M, Eastham JA, Rabbani F, Fair W, Wheeler TM, Hammerer PG, Haese A, Erbersdobler A, Huland H, Scardino PT, Kattan MW. Analysis of clinical stage T2 prostate cancer: do current subclassifications represent an improvement? J Clin Oncol. 2002 Apr 15; 20(8):2025-30. PMID: 11956261.
      View in: PubMed
    160. Andrews B, Shariat SF, Kim JH, Wheeler TM, Slawin KM, Lerner SP. Preoperative plasma levels of interleukin-6 and its soluble receptor predict disease recurrence and survival of patients with bladder cancer. J Urol. 2002 Mar; 167(3):1475-81. PMID: 11832773.
      View in: PubMed
    161. Shariat SF, Lamb DJ, Kattan MW, Nguyen C, Kim J, Beck J, Wheeler TM, Slawin KM. Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and -3 with prostate cancer invasion, progression, and metastasis. J Clin Oncol. 2002 Feb 1; 20(3):833-41. PMID: 11821468.
      View in: PubMed
    162. Hull GW, Rabbani F, Abbas F, Wheeler TM, Kattan MW, Scardino PT. Cancer control with radical prostatectomy alone in 1,000 consecutive patients. J Urol. 2002 Feb; 167(2 Pt 1):528-34. PMID: 11792912.
      View in: PubMed
    163. Slawin KM, Canto EI, Shariat SF, Gore JL, Kim E, Kattan MW, Wheeler TM, Nath RK. Sural Nerve Interposition Grafting during Radical Prostatectomy. Rev Urol. 2002; 4(1):17-23. PMID: 16985648; PMCID: PMC1475960.
    164. Teh BS, Aguilar-Cordova E, Vlachaki MT, Aguilar L, Mai WY, Caillouet J, Davis M, Miles B, Kadmon D, Ayala G, Lu HH, Chiu JK, Carpenter LS, Woo SY, Grant WH, Wheeler T, Thompson TC, Butler EB. Combining radiotherapy with gene therapy (from the bench to the bedside): a novel treatment strategy for prostate cancer. Oncologist. 2002; 7(5):458-66. PMID: 12401909.
      View in: PubMed
    165. Shariat SF, Kim JH, Andrews B, Kattan MW, Wheeler TM, Kim IY, Lerner SP, Slawin KM. Preoperative plasma levels of transforming growth factor beta(1) strongly predict clinical outcome in patients with bladder carcinoma. Cancer. 2001 Dec 15; 92(12):2985-92. PMID: 11753975.
      View in: PubMed
    166. Shariat SF, Andrews B, Kattan MW, Kim J, Wheeler TM, Slawin KM. Plasma levels of interleukin-6 and its soluble receptor are associated with prostate cancer progression and metastasis. Urology. 2001 Dec; 58(6):1008-15. PMID: 11744478.
      View in: PubMed
    167. Kothari PS, Scardino PT, Ohori M, Kattan MW, Wheeler TM. Incidence, location, and significance of periprostatic and periseminal vesicle lymph nodes in prostate cancer. Am J Surg Pathol. 2001 Nov; 25(11):1429-32. PMID: 11684961.
      View in: PubMed
    168. Miles BJ, Shalev M, Aguilar-Cordova E, Timme TL, Lee HM, Yang G, Adler HL, Kernen K, Pramudji CK, Satoh T, Gdor Y, Ren C, Ayala G, Wheeler TM, Butler EB, Kadmon D, Thompson TC. Prostate-specific antigen response and systemic T cell activation after in situ gene therapy in prostate cancer patients failing radiotherapy. Hum Gene Ther. 2001 Nov 1; 12(16):1955-67. PMID: 11686937.
      View in: PubMed
    169. Teh BS, Aguilar-Cordova E, Kernen K, Chou CC, Shalev M, Vlachaki MT, Miles B, Kadmon D, Mai WY, Caillouet J, Davis M, Ayala G, Wheeler T, Brady J, Carpenter LS, Lu HH, Chiu JK, Woo SY, Thompson T, Butler EB. Phase I/II trial evaluating combined radiotherapy and in situ gene therapy with or without hormonal therapy in the treatment of prostate cancer--a preliminary report. Int J Radiat Oncol Biol Phys. 2001 Nov 1; 51(3):605-13. PMID: 11597799.
      View in: PubMed
    170. Ayala GE, Wheeler TM, Shine HD, Schmelz M, Frolov A, Chakraborty S, Rowley D. In vitro dorsal root ganglia and human prostate cell line interaction: redefining perineural invasion in prostate cancer. Prostate. 2001 Nov 1; 49(3):213-23. PMID: 11746267.
      View in: PubMed
    171. Kim JH, Shariat SF, Kim IY, Menesses-Diaz A, Tokunaga H, Wheeler TM, Lerner SP. Predictive value of expression of transforming growth factor-beta(1) and its receptors in transitional cell carcinoma of the urinary bladder. Cancer. 2001 Sep 15; 92(6):1475-83. PMID: 11745225.
      View in: PubMed
    172. Malins DC, Johnson PM, Wheeler TM, Barker EA, Polissar NL, Vinson MA. Age-related radical-induced DNA damage is linked to prostate cancer. Cancer Res. 2001 Aug 15; 61(16):6025-8. PMID: 11507046.
      View in: PubMed
    173. Maru N, Ohori M, Kattan MW, Scardino PT, Wheeler TM. Prognostic significance of the diameter of perineural invasion in radical prostatectomy specimens. Hum Pathol. 2001 Aug; 32(8):828-33. PMID: 11521227.
      View in: PubMed
    174. Shappell SB, Manning S, Boeglin WE, Guan YF, Roberts RL, Davis L, Olson SJ, Jack GS, Coffey CS, Wheeler TM, Breyer MD, Brash AR. Alterations in lipoxygenase and cyclooxygenase-2 catalytic activity and mRNA expression in prostate carcinoma. Neoplasia. 2001 Jul-Aug; 3(4):287-303. PMID: 11571629; PMCID: PMC1505867.
    175. Shariat SF, Shalev M, Menesses-Diaz A, Kim IY, Kattan MW, Wheeler TM, Slawin KM. Preoperative plasma levels of transforming growth factor beta(1) (TGF-beta(1)) strongly predict progression in patients undergoing radical prostatectomy. J Clin Oncol. 2001 Jun 1; 19(11):2856-64. PMID: 11387358.
      View in: PubMed
    176. Kim ED, Nath R, Kadmon D, Lipshultz LI, Miles BJ, Slawin KM, Tang HY, Wheeler T, Scardino PT. Bilateral nerve graft during radical retropubic prostatectomy: 1-year followup. J Urol. 2001 Jun; 165(6 Pt 1):1950-6. PMID: 11371887.
      View in: PubMed
    177. Thompson TC, Timme TL, Ebara S, Satoh T, Yang G, Wang J, Miles BJ, Ayala G, Wheeler TM, Kadmon D. In situ gene therapy for prostate cancer: immunomodulatory approaches. Expert Opin Biol Ther. 2001 May; 1(3):481-95. PMID: 11727520.
      View in: PubMed
    178. Gore JL, Shariat SF, Miles BJ, Kadmon D, Jiang N, Wheeler TM, Slawin KM. Optimal combinations of systematic sextant and laterally directed biopsies for the detection of prostate cancer. J Urol. 2001 May; 165(5):1554-9. PMID: 11342916.
      View in: PubMed
    179. Herman CM, Kattan MW, Ohori M, Scardino PT, Wheeler TM. Primary Gleason pattern as a predictor of disease progression in gleason score 7 prostate cancer: a multivariate analysis of 823 men treated with radical prostatectomy. Am J Surg Pathol. 2001 May; 25(5):657-60. PMID: 11342779.
      View in: PubMed
    180. Byrne RR, Shariat SF, Brown R, Kattan MW, Morton RA JR, Wheeler TM, Lerner SP. E-cadherin immunostaining of bladder transitional cell carcinoma, carcinoma in situ and lymph node metastases with long-term followup. J Urol. 2001 May; 165(5):1473-9. PMID: 11342899.
      View in: PubMed
    181. Bova GS, Parmigiani G, Epstein JI, Wheeler T, Mucci NR, Rubin MA. Web-based tissue microarray image data analysis: initial validation testing through prostate cancer Gleason grading. Hum Pathol. 2001 Apr; 32(4):417-27. PMID: 11331959.
      View in: PubMed
    182. Amrikachi M, Ramzy I, Rubenfeld S, Wheeler TM. Accuracy of fine-needle aspiration of thyroid. Arch Pathol Lab Med. 2001 Apr; 125(4):484-8. PMID: 11260620.
      View in: PubMed
    183. Dal Bello-Haas V, Andrews-Hinders D, Richer CB, Blakely-Adams C, Hanson J, Hammel J, Kelly D, Kloos A, Pioro EP, Powazki RD, Wheeler T, Mitsumoto H. Development, analysis, refinement, and utility of an interdisciplinary amyotrophic lateral sclerosis database. Amyotroph Lateral Scler Other Motor Neuron Disord. 2001 Mar; 2(1):39-46. PMID: 11465932.
      View in: PubMed
    184. Muezzinoglu B, Erdamar S, Chakraborty S, Wheeler TM. Verumontanum mucosal gland hyperplasia is associated with atypical adenomatous hyperplasia of the prostate. Arch Pathol Lab Med. 2001 Mar; 125(3):358-60. PMID: 11231483.
      View in: PubMed
    185. Leventis AK, Shariat SF, Kattan MW, Butler EB, Wheeler TM, Slawin KM. Prediction of response to salvage radiation therapy in patients with prostate cancer recurrence after radical prostatectomy. J Clin Oncol. 2001 Feb 15; 19(4):1030-9. PMID: 11181666.
      View in: PubMed
    186. Shappell SB, Gupta RA, Manning S, Whitehead R, Boeglin WE, Schneider C, Case T, Price J, Jack GS, Wheeler TM, Matusik RJ, Brash AR, Dubois RN. 15S-Hydroxyeicosatetraenoic acid activates peroxisome proliferator-activated receptor gamma and inhibits proliferation in PC3 prostate carcinoma cells. Cancer Res. 2001 Jan 15; 61(2):497-503. PMID: 11212240.
      View in: PubMed
    187. Bosio PM, Wheeler T, Anthony F, Conroy R, O'herlihy C, McKenna P. Maternal plasma vascular endothelial growth factor concentrations in normal and hypertensive pregnancies and their relationship to peripheral vascular resistance. Am J Obstet Gynecol. 2001 Jan; 184(2):146-52. PMID: 11174494.
      View in: PubMed
    188. Chang S, Hursting SD, Contois JH, Strom SS, Yamamura Y, Babaian RJ, Troncoso P, Scardino PS, Wheeler TM, Amos CI, Spitz MR. Leptin and prostate cancer. Prostate. 2001 Jan 1; 46(1):62-7. PMID: 11170133.
      View in: PubMed
    189. Allsbrook WC, Mangold KA, Johnson MH, Lane RB, Lane CG, Amin MB, Bostwick DG, Humphrey PA, Jones EC, Reuter VE, Sakr W, Sesterhenn IA, Troncoso P, Wheeler TM, Epstein JI. Interobserver reproducibility of Gleason grading of prostatic carcinoma: urologic pathologists. Hum Pathol. 2001 Jan; 32(1):74-80. PMID: 11172298.
      View in: PubMed
    190. Shariat SF, Pahlavan S, Baseman AG, Brown RM, Green AE, Wheeler TM, Lerner SP. E-cadherin expression predicts clinical outcome in carcinoma in situ of the urinary bladder. Urology. 2001 Jan; 57(1):60-5. PMID: 11164145.
      View in: PubMed
    191. Slawin KM, Shariat SF, Nguyen C, Leventis AK, Song W, Kattan MW, Young CY, Tindall DJ, Wheeler TM. Detection of metastatic prostate cancer using a splice variant-specific reverse transcriptase-polymerase chain reaction assay for human glandular kallikrein. Cancer Res. 2000 Dec 15; 60(24):7142-8. PMID: 11156423.
      View in: PubMed
    192. Rabbani F, Stapleton AM, Kattan MW, Wheeler TM, Scardino PT. Factors predicting recovery of erections after radical prostatectomy. J Urol. 2000 Dec; 164(6):1929-34. PMID: 11061884.
      View in: PubMed
    193. Dal Bello-Haas V, Andrews-Hinders D, Bocian J, Mascha E, Wheeler T, Mitsumoto H. Spiritual well-being of the individual with amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord. 2000 Dec; 1(5):337-41. PMID: 11464852.
      View in: PubMed
    194. Malone CL, Wheeler T, Taylor JF, Davis SK. Phylogeography of the Caribbean rock iguana (Cyclura): implications for conservation and insights on the biogeographic history of the West Indies. Mol Phylogenet Evol. 2000 Nov; 17(2):269-79. PMID: 11083940.
      View in: PubMed
    195. Shariat SF, Weizer AZ, Green A, Laucirica R, Frolov A, Wheeler TM, Lerner SP. Prognostic value of P53 nuclear accumulation and histopathologic features in T1 transitional cell carcinoma of the urinary bladder. Urology. 2000 Nov 1; 56(5):735-40. PMID: 11068290.
      View in: PubMed
    196. Shimura S, Yang G, Ebara S, Wheeler TM, Frolov A, Thompson TC. Reduced infiltration of tumor-associated macrophages in human prostate cancer: association with cancer progression. Cancer Res. 2000 Oct 15; 60(20):5857-61. PMID: 11059783.
      View in: PubMed
    197. Shariat SF, Bergamaschi F, Adler HL, Nguyen C, Kattan MW, Wheeler TM, Slawin KM. Correlation of preoperative plasma IGF-I levels with pathologic parameters and progression in patients undergoing radical prostatectomy. Urology. 2000 Sep 1; 56(3):423-9. PMID: 10962307.
      View in: PubMed
    198. Yang G, Addai J, Ittmann M, Wheeler TM, Thompson TC. Elevated caveolin-1 levels in African-American versus white-American prostate cancer. Clin Cancer Res. 2000 Sep; 6(9):3430-3. PMID: 10999725.
      View in: PubMed
    199. Sutton MA, Freund CT, Berkman SA, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Lerner SP. In vivo adenovirus-mediated suicide gene therapy of orthotopic bladder cancer. Mol Ther. 2000 Sep; 2(3):211-7. PMID: 10985951.
      View in: PubMed
    200. Ayala G, Wheeler TM, Shalev M, Thompson TC, Miles B, Aguilar-Cordova E, Chakraborty S, Kadmon D. Cytopathic effect of in situ gene therapy in prostate cancer. Hum Pathol. 2000 Jul; 31(7):866-70. PMID: 10923926.
      View in: PubMed
    201. Herman CM, Wilcox GE, Kattan MW, Scardino PT, Wheeler TM. Lymphovascular invasion as a predictor of disease progression in prostate cancer. Am J Surg Pathol. 2000 Jun; 24(6):859-63. PMID: 10843289.
      View in: PubMed
    202. Spitz MR, Strom SS, Yamamura Y, Troncoso P, Babaian RJ, Scardino PT, Wheeler T, Amos CI, von Eschenbach A, Kagan J. Epidemiologic determinants of clinically relevant prostate cancer. Int J Cancer. 2000 May 20; 89(3):259-64. PMID: 10861502.
      View in: PubMed
    203. Stepanova L, Yang G, DeMayo F, Wheeler TM, Finegold M, Thompson TC, Harper JW. Induction of human Cdc37 in prostate cancer correlates with the ability of targeted Cdc37 expression to promote prostatic hyperplasia. Oncogene. 2000 Apr 27; 19(18):2186-93. PMID: 10822368.
      View in: PubMed
    204. Mikolajczyk SD, Millar LS, Wang TJ, Rittenhouse HG, Marks LS, Song W, Wheeler TM, Slawin KM. A precursor form of prostate-specific antigen is more highly elevated in prostate cancer compared with benign transition zone prostate tissue. Cancer Res. 2000 Feb 1; 60(3):756-9. PMID: 10676664.
      View in: PubMed
    205. Lotan Y, Xu XC, Shalev M, Lotan R, Williams R, Wheeler TM, Thompson TC, Kadmon D. Differential expression of nuclear retinoid receptors in normal and malignant prostates. J Clin Oncol. 2000 Jan; 18(1):116-21. PMID: 10623701.
      View in: PubMed
    206. Mikolajczyk SD, Millar LS, Wang TJ, Rittenhouse HG, Wolfert RL, Marks LS, Song W, Wheeler TM, Slawin KM. "BPSA," a specific molecular form of free prostate-specific antigen, is found predominantly in the transition zone of patients with nodular benign prostatic hyperplasia. Urology. 2000 Jan; 55(1):41-5. PMID: 10654892.
      View in: PubMed
    207. Yang G, Truong LD, Wheeler TM, Thompson TC. Caveolin-1 expression in clinically confined human prostate cancer: a novel prognostic marker. Cancer Res. 1999 Nov 15; 59(22):5719-23. PMID: 10582690.
      View in: PubMed
    208. Tokunaga H, Lee DH, Kim IY, Wheeler TM, Lerner SP. Decreased expression of transforming growth factor beta receptor type I is associated with poor prognosis in bladder transitional cell carcinoma patients. Clin Cancer Res. 1999 Sep; 5(9):2520-5. PMID: 10499628.
      View in: PubMed
    209. Vallée JP, MacFall JR, Lazeyras F, Wheeler T, Hedlund LW, Spritzer CE, Coleman RE, Sostman HD. Pitfalls in myocardial perfusion assessment with dynamic MR imaging after administration of a contrast material bolus in dogs. Acad Radiol. 1999 Sep; 6(9):512-20. PMID: 10894059.
      View in: PubMed
    210. Anton RC, Kattan MW, Chakraborty S, Wheeler TM. Postatrophic hyperplasia of the prostate: lack of association with prostate cancer. Am J Surg Pathol. 1999 Aug; 23(8):932-6. PMID: 10435563.
      View in: PubMed
    211. Erdamar S, Yang G, Harper JW, Lu X, Kattan MW, Thompson TC, Wheeler TM. Levels of expression of p27KIP1 protein in human prostate and prostate cancer: an immunohistochemical analysis. Mod Pathol. 1999 Aug; 12(8):751-5. PMID: 10463475.
      View in: PubMed
    212. Wheeler T, Evans PW, Anthony FW, Godfrey KM, Howe DT, Osmond C. Relationship between maternal serum vascular endothelial growth factor concentration in early pregnancy and fetal and placental growth. Hum Reprod. 1999 Jun; 14(6):1619-23. PMID: 10357987.
      View in: PubMed
    213. Herman JR, Adler HL, Aguilar-Cordova E, Rojas-Martinez A, Woo S, Timme TL, Wheeler TM, Thompson TC, Scardino PT. In situ gene therapy for adenocarcinoma of the prostate: a phase I clinical trial. Hum Gene Ther. 1999 May 1; 10(7):1239-49. PMID: 10340555.
      View in: PubMed
    214. Kattan MW, Wheeler TM, Scardino PT. Postoperative nomogram for disease recurrence after radical prostatectomy for prostate cancer. J Clin Oncol. 1999 May; 17(5):1499-507. PMID: 10334537.
      View in: PubMed
    215. Wheeler T. Telepathology's slow start. Telemed Today. 1999 Feb; 7(1):37-9. PMID: 10350943.
      View in: PubMed
    216. Ohori M, Abbas F, Wheeler TM, Kattan MW, Scardino PT, Lerner SP. Pathological features and prognostic significance of prostate cancer in the apical section determined by whole mount histology. J Urol. 1999 Feb; 161(2):500-4. PMID: 9915435.
      View in: PubMed
    217. Topaz O, Vetrovec GW, Wheeler T, Holdaway BK. Dual anterior interventricular arteries. Clin Anat. 1999; 12(3):153-8. PMID: 10340454.
      View in: PubMed
    218. Kim ED, Scardino PT, Hampel O, Mills NL, Wheeler TM, Nath RK. Interposition of sural nerve restores function of cavernous nerves resected during radical prostatectomy. J Urol. 1999 Jan; 161(1):188-92. PMID: 10037395.
      View in: PubMed
    219. Wheeler T, Stenning S, Negus S, Picken S, Metcalfe S. Evidence to support a change in follow-up policy for patients with breast cancer: time to first relapse and hazard rate analysis. Clin Oncol (R Coll Radiol). 1999; 11(3):169-73. PMID: 10465470.
      View in: PubMed
    220. Hu JC, Palapattu GS, Kattan MW, Scardino PT, Wheeler TM. The association of selected pathological features with prostate cancer in a single-needle biopsy accession. Hum Pathol. 1998 Dec; 29(12):1536-8. PMID: 9865844.
      View in: PubMed
    221. Malliri A, Symons M, Hennigan RF, Hurlstone AF, Lamb RF, Wheeler T, Ozanne BW. The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells. J Cell Biol. 1998 Nov 16; 143(4):1087-99. PMID: 9817764; PMCID: PMC2132955.
    222. Wilcox G, Soh S, Chakraborty S, Scardino PT, Wheeler TM. Patterns of high-grade prostatic intraepithelial neoplasia associated with clinically aggressive prostate cancer. Hum Pathol. 1998 Oct; 29(10):1119-23. PMID: 9781651.
      View in: PubMed
    223. Krouskop TA, Wheeler TM, Kallel F, Garra BS, Hall T. Elastic moduli of breast and prostate tissues under compression. Ultrason Imaging. 1998 Oct; 20(4):260-74. PMID: 10197347.
      View in: PubMed
    224. Yang G, Truong LD, Timme TL, Ren C, Wheeler TM, Park SH, Nasu Y, Bangma CH, Kattan MW, Scardino PT, Thompson TC. Elevated expression of caveolin is associated with prostate and breast cancer. Clin Cancer Res. 1998 Aug; 4(8):1873-80. PMID: 9717814.
      View in: PubMed
    225. Wheeler TM, Dillioglugil O, Kattan MW, Arakawa A, Soh S, Suyama K, Ohori M, Scardino PT. Clinical and pathological significance of the level and extent of capsular invasion in clinical stage T1-2 prostate cancer. Hum Pathol. 1998 Aug; 29(8):856-62. PMID: 9712429.
      View in: PubMed
    226. Vallée JP, Sostman HD, MacFall JR, DeGrado TR, Zhang J, Sebbag L, Cobb FR, Wheeler T, Hedlund LW, Turkington TG, Spritzer CE, Coleman RE. Quantification of myocardial perfusion by MRI after coronary occlusion. Magn Reson Med. 1998 Aug; 40(2):287-97. PMID: 9702711.
      View in: PubMed
    227. Pelham WE, Wheeler T, Chronis A. Empirically supported psychosocial treatments for attention deficit hyperactivity disorder. J Clin Child Psychol. 1998 Jun; 27(2):190-205. PMID: 9648036.
      View in: PubMed
    228. Allen A, Wheeler T. The leaders: U.S. programs doing more than 500 interactive consults in 1997. Telemed Today. 1998 Jun; 6(3):36-7. PMID: 10183143.
      View in: PubMed
    229. Hampel OZ, Kattan MW, Yang G, Haidacher SJ, Saleh GY, Thompson TC, Wheeler TM, Marcelli M. Quantitative immunohistochemical analysis of insulin-like growth factor binding protein-3 in human prostatic adenocarcinoma: a prognostic study. J Urol. 1998 Jun; 159(6):2220-5. PMID: 9598573.
      View in: PubMed
    230. Kattan MW, Eastham JA, Stapleton AM, Wheeler TM, Scardino PT. A preoperative nomogram for disease recurrence following radical prostatectomy for prostate cancer. J Natl Cancer Inst. 1998 May 20; 90(10):766-71. PMID: 9605647.
      View in: PubMed
    231. Anton RC, Chakraborty S, Wheeler TM. The significance of intraluminal prostatic crystalloids in benign needle biopsies. Am J Surg Pathol. 1998 Apr; 22(4):446-9. PMID: 9537472.
      View in: PubMed
    232. Evans PW, Wheeler T, Anthony FW, Osmond C. A longitudinal study of maternal serum vascular endothelial growth factor in early pregnancy. Hum Reprod. 1998 Apr; 13(4):1057-62. PMID: 9619570.
      View in: PubMed
    233. Ren C, Yang G, Timme TL, Wheeler TM, Thompson TC. Reduced lysyl oxidase messenger RNA levels in experimental and human prostate cancer. Cancer Res. 1998 Mar 15; 58(6):1285-90. PMID: 9515817.
      View in: PubMed
    234. Woods JE, Soh S, Wheeler TM. Distribution and significance of microcalcifications in the neoplastic and nonneoplastic prostate. Arch Pathol Lab Med. 1998 Feb; 122(2):152-5. PMID: 9499358.
      View in: PubMed
    235. Stapleton AM, Zbell P, Kattan MW, Yang G, Wheeler TM, Scardino PT, Thompson TC. Assessment of the biologic markers p53, Ki-67, and apoptotic index as predictive indicators of prostate carcinoma recurrence after surgery. Cancer. 1998 Jan 1; 82(1):168-75. PMID: 9428494.
      View in: PubMed
    236. Lin WW, Lamb DJ, Wheeler TM, Lipshultz LI, Kim ED. In situ end-labeling of human testicular tissue demonstrates increased apoptosis in conditions of abnormal spermatogenesis. Fertil Steril. 1997 Dec; 68(6):1065-9. PMID: 9418698.
      View in: PubMed
    237. Vallée JP, Sostman HD, MacFall JR, Wheeler T, Hedlund LW, Spritzer CE, Coleman RE. MRI quantitative myocardial perfusion with compartmental analysis: a rest and stress study. Magn Reson Med. 1997 Dec; 38(6):981-9. PMID: 9402200.
      View in: PubMed
    238. Elbadawi A, Mathews R, Light JK, Wheeler TM. Immunohistochemical and ultrastructural study of rhabdosphincter component of the prostatic capsule. J Urol. 1997 Nov; 158(5):1819-28. PMID: 9334610.
      View in: PubMed
    239. Lin WW, Lamb DJ, Wheeler TM, Abrams J, Lipshultz LI, Kim ED. Apoptotic frequency is increased in spermatogenic maturation arrest and hypospermatogenic states. J Urol. 1997 Nov; 158(5):1791-3. PMID: 9334603.
      View in: PubMed
    240. Arakawa A, Soh S, Chakraborty S, Scardino PT, Wheeler TM. Prognostic significance of angiogenesis in clinically localized prostate cancer (staining for Factor VIII-related antigen and CD34 Antigen. Prostate Cancer Prostatic Dis. 1997 Sep; 1(1):32-38. PMID: 12496931.
      View in: PubMed
    241. Lee B, Wheeler T. Emergence and recovery from anesthesia for pediatrics patients in the post-anesthesia care unit. Pediatr Ann. 1997 Aug; 26(8):461-9. PMID: 9263300.
      View in: PubMed
    242. Stapleton AM, Timme TL, Gousse AE, Li QF, Tobon AA, Kattan MW, Slawin KM, Wheeler TM, Scardino PT, Thompson TC. Primary human prostate cancer cells harboring p53 mutations are clonally expanded in metastases. Clin Cancer Res. 1997 Aug; 3(8):1389-97. PMID: 9815823.
      View in: PubMed
    243. Dillioglugil O, Leibman BD, Kattan MW, Seale-Hawkins C, Wheeler TM, Scardino PT. Hazard rates for progression after radical prostatectomy for clinically localized prostate cancer. Urology. 1997 Jul; 50(1):93-9. PMID: 9218025.
      View in: PubMed
    244. Taylor CM, Stevens H, Anthony FW, Wheeler T. Influence of hypoxia on vascular endothelial growth factor and chorionic gonadotrophin production in the trophoblast-derived cell lines: JEG, JAr and BeWo. Placenta. 1997 Jul-Aug; 18(5-6):451-8. PMID: 9250709.
      View in: PubMed
    245. Soh S, Kattan MW, Berkman S, Wheeler TM, Scardino PT. Has there been a recent shift in the pathological features and prognosis of patients treated with radical prostatectomy? J Urol. 1997 Jun; 157(6):2212-8. PMID: 9146618.
      View in: PubMed
    246. Evans P, Wheeler T, Anthony F, Osmond C. Maternal serum vascular endothelial growth factor during early pregnancy. Clin Sci (Lond). 1997 Jun; 92(6):567-71. PMID: 9205416.
      View in: PubMed
    247. Anthony FW, Evans PW, Wheeler T, Wood PJ. Variation in detection of VEGF in maternal serum by immunoassay and the possible influence of binding proteins. Ann Clin Biochem. 1997 May; 34 ( Pt 3):276-80. PMID: 9158825.
      View in: PubMed
    248. Light JK, Rapoll E, Wheeler TM. The striated urethral sphincter: muscle fibre types and distribution in the prostatic capsule. Br J Urol. 1997 Apr; 79(4):539-42. PMID: 9126081.
      View in: PubMed
    249. Sutton MA, Berkman SA, Chen SH, Block A, Dang TD, Kattan MW, Wheeler TM, Rowley DR, Woo SL, Lerner SP. Adenovirus-mediated suicide gene therapy for experimental bladder cancer. Urology. 1997 Feb; 49(2):173-80. PMID: 9037277.
      View in: PubMed
    250. Kattan MW, Stapleton AM, Wheeler TM, Scardino PT. Evaluation of a nomogram used to predict the pathologic stage of clinically localized prostate carcinoma. Cancer. 1997 Feb 1; 79(3):528-37. PMID: 9028364.
      View in: PubMed
    251. Yang G, Wheeler TM, Kattan MW, Scardino PT, Thompson TC. Perineural invasion of prostate carcinoma cells is associated with reduced apoptotic index. Cancer. 1996 Sep 15; 78(6):1267-71. PMID: 8826950.
      View in: PubMed
    252. Goto Y, Ohori M, Arakawa A, Kattan MW, Wheeler TM, Scardino PT. Distinguishing clinically important from unimportant prostate cancers before treatment: value of systematic biopsies. J Urol. 1996 Sep; 156(3):1059-63. PMID: 8709307.
      View in: PubMed
    253. McArthur WP, Bloom K, Taylor M, Wheeler T, Smith J, Magnusson NI. Peripheral blood leukocyte populations in the elderly with and without periodontal disease. J Clin Periodontol. 1996 Sep; 23(9):846-52. PMID: 8891936.
      View in: PubMed
    254. Sakr WA, Wheeler TM, Blute M, Bodo M, Calle-Rodrigue R, Henson DE, Mostofi FK, Seiffert J, Wojno K, Zincke H. Staging and reporting of prostate cancer--sampling of the radical prostatectomy specimen. Cancer. 1996 Jul 15; 78(2):366-8. PMID: 8674019.
      View in: PubMed
    255. Bostwick DG, Wheeler TM, Blute M, Barrett DM, MacLennan GT, Sebo TJ, Scardino PT, Humphrey PA, Hudson MA, Fradet Y, Miller GJ, Crawford ED, Blumenstein BA, Mahran HE, Miles BJ. Optimized microvessel density analysis improves prediction of cancer stage from prostate needle biopsies. Urology. 1996 Jul; 48(1):47-57. PMID: 8693651.
      View in: PubMed
    256. Williams RH, Stapleton AM, Yang G, Truong LD, Rogers E, Timme TL, Wheeler TM, Scardino PT, Thompson TC. Reduced levels of transforming growth factor beta receptor type II in human prostate cancer: an immunohistochemical study. Clin Cancer Res. 1996 Apr; 2(4):635-40. PMID: 9816213.
      View in: PubMed
    257. Rogers E, Eastham JA, Ohori M, Sariyuce O, Aihara M, Wheeler TM, Scardino PT. Impalpable prostate cancer: clinicopathological features. Br J Urol. 1996 Mar; 77(3):429-32. PMID: 8814851.
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    258. Yang G, Stapleton AM, Wheeler TM, Truong LD, Timme TL, Scardino PT, Thompson TC. Clustered p53 immunostaining: a novel pattern associated with prostate cancer progression. Clin Cancer Res. 1996 Feb; 2(2):399-401. PMID: 9816183.
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    259. Wheeler TM. Influence of irradiation and androgen ablation on prostatic intraepithelial neoplasia. Eur Urol. 1996; 30(2):261-4. PMID: 8875209.
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    260. Leibman BD, Dillioglugil O, Wheeler TM, Scardino PT. Distant metastasis after radical prostatectomy in patients without an elevated serum prostate specific antigen level. Cancer. 1995 Dec 15; 76(12):2530-4. PMID: 8625081.
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    261. Gaudin PB, Wheeler TM, Epstein JI. Verumontanum mucosal gland hyperplasia in prostatic needle biopsy specimens. A mimic of low grade prostatic adenocarcinoma. Am J Clin Pathol. 1995 Dec; 104(6):620-6. PMID: 8526203.
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    262. Gilcrease MZ, Schmidt L, Zbar B, Truong L, Rutledge M, Wheeler TM. Somatic von Hippel-Lindau mutation in clear cell papillary cystadenoma of the epididymis. Hum Pathol. 1995 Dec; 26(12):1341-6. PMID: 8522307.
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    263. Ohori M, Wheeler TM, Kattan MW, Goto Y, Scardino PT. Prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol. 1995 Nov; 154(5):1818-24. PMID: 7563355.
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    264. McArthur WP, Bloom C, Taylor M, Smith J, Wheeler T, Magnusson NI. Antibody responses to suspected periodontal pathogens in elderly subjects with periodontal disease. J Clin Periodontol. 1995 Nov; 22(11):842-9. PMID: 8550860.
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    265. Eastham JA, Stapleton AM, Gousse AE, Timme TL, Yang G, Slawin KM, Wheeler TM, Scardino PT, Thompson TC. Association of p53 mutations with metastatic prostate cancer. Clin Cancer Res. 1995 Oct; 1(10):1111-8. PMID: 9815901.
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    266. Wheeler T, Chard T, Anthony F, Osmond C. Relationships between the uterine environment and maternal plasma concentrations of insulin-like growth factor binding protein-1 and placental protein 14 in early pregnancy. Hum Reprod. 1995 Oct; 10(10):2700-4. PMID: 8567796.
      View in: PubMed
    267. Arakawa A, Song S, Scardino PT, Wheeler TM. High grade prostatic intraepithelial neoplasia in prostates removed following irradiation failure in the treatment of prostatic adenocarcinoma. Pathol Res Pract. 1995 Sep; 191(9):868-72. PMID: 8606867.
      View in: PubMed
    268. Bjornsson BL, Truong LD, Cartwright J, Abrams J, Rutledge ML, Wheeler TM. Pelvic lymph node histiocytosis mimicking metastatic prostatic adenocarcinoma: association with hip prostheses. J Urol. 1995 Aug; 154(2 Pt 1):470-3. PMID: 7609108.
      View in: PubMed
    269. Epstein JI, Grignon DJ, Humphrey PA, McNeal JE, Sesterhenn IA, Troncoso P, Wheeler TM. Interobserver reproducibility in the diagnosis of prostatic intraepithelial neoplasia. Am J Surg Pathol. 1995 Aug; 19(8):873-86. PMID: 7611534.
      View in: PubMed
    270. Howe D, Wheeler T. Early origin of coronary heart disease. Maternal nutrition in early pregnancy may affect placental ratio. BMJ. 1995 Jun 3; 310(6992):1468. PMID: 7613292; PMCID: PMC2549834.
    271. Ostrowski ML, Brown RW, Wheeler TM, Green LK, Schaffner DL. Leu-7 immunoreactivity in cytologic specimens of thyroid lesions, with emphasis on follicular neoplasms. Diagn Cytopathol. 1995 Jun; 12(4):297-302. PMID: 7544717.
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    272. Wheeler T, Elcock CL, Anthony FW. Angiogenesis and the placental environment. Placenta. 1995 Apr; 16(3):289-96. PMID: 7543674.
      View in: PubMed
    273. Aihara M, Scardino PT, Truong LD, Wheeler TM, Goad JR, Yang G, Thompson TC. The frequency of apoptosis correlates with the prognosis of Gleason Grade 3 adenocarcinoma of the prostate. Cancer. 1995 Jan 15; 75(2):522-9. PMID: 7529128.
      View in: PubMed
    274. Gagucas RJ, Brown RW, Wheeler TM. Verumontanum mucosal gland hyperplasia. Am J Surg Pathol. 1995 Jan; 19(1):30-6. PMID: 7802135.
      View in: PubMed
    275. Rogers E, Ohori M, Kassabian VS, Wheeler TM, Scardino PT. Salvage radical prostatectomy: outcome measured by serum prostate specific antigen levels. J Urol. 1995 Jan; 153(1):104-10. PMID: 7526002.
      View in: PubMed
    276. Norberg M, Holmberg L, Wheeler T, Magnusson A. Five year follow-up after radical prostatectomy for localized prostate cancer--a study of the impact of different tumor variables on progression. Scand J Urol Nephrol. 1994 Dec; 28(4):391-9. PMID: 7533926.
      View in: PubMed
    277. Ohori M, Wheeler TM, Dunn JK, Stamey TA, Scardino PT. The pathological features and prognosis of prostate cancer detectable with current diagnostic tests. J Urol. 1994 Nov; 152(5 Pt 2):1714-20. PMID: 7523718.
      View in: PubMed
    278. Wheeler TM, Lebovitz RM. Fresh tissue harvest for research from prostatectomy specimens. Prostate. 1994 Nov; 25(5):274-9. PMID: 7526353.
      View in: PubMed
    279. Ohori M, Goad JR, Wheeler TM, Eastham JA, Thompson TC, Scardino PT. Can radical prostatectomy alter the progression of poorly differentiated prostate cancer? J Urol. 1994 Nov; 152(5 Pt 2):1843-9. PMID: 7523732.
      View in: PubMed
    280. Pindur A, Chakraborty S, Welch DG, Wheeler TM. DNA ploidy measurements in prostate cancer: differences between image analysis and flow cytometry and clinical implications. Prostate. 1994 Oct; 25(4):189-98. PMID: 8084836.
      View in: PubMed
    281. Aihara M, Truong LD, Dunn JK, Wheeler TM, Scardino PT, Thompson TC. Frequency of apoptotic bodies positively correlates with Gleason grade in prostate cancer. Hum Pathol. 1994 Aug; 25(8):797-801. PMID: 7520020.
      View in: PubMed
    282. Anthony FW, Wheeler T, Elcock CL, Pickett M, Thomas EJ. Short report: identification of a specific pattern of vascular endothelial growth factor mRNA expression in human placenta and cultured placental fibroblasts. Placenta. 1994 Jul; 15(5):557-61. PMID: 7997455.
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    283. Ohori M, Egawa S, Shinohara K, Wheeler TM, Scardino PT. Detection of microscopic extracapsular extension prior to radical prostatectomy for clinically localized prostate cancer. Br J Urol. 1994 Jul; 74(1):72-9. PMID: 7519116.
      View in: PubMed
    284. Ohori M, Wheeler TM, Scardino PT. The New American Joint Committee on Cancer and International Union Against Cancer TNM classification of prostate cancer. Clinicopathologic correlations. Cancer. 1994 Jul 1; 74(1):104-14. PMID: 7516262.
      View in: PubMed
    285. Aihara M, Lebovitz RM, Wheeler TM, Kinner BM, Ohori M, Scardino PT. Prostate specific antigen and gleason grade: an immunohistochemical study of prostate cancer. J Urol. 1994 Jun; 151(6):1558-64. PMID: 7514688.
      View in: PubMed
    286. Truong LD, Ostrowski ML, Wheeler TM. Tamm-Horsfall protein in bladder tissue. Morphologic spectrum and clinical significance. Am J Surg Pathol. 1994 Jun; 18(6):615-22. PMID: 8179076.
      View in: PubMed
    287. Greene DR, Rogers E, Wessels EC, Wheeler TM, Taylor SR, Santucci RA, Thompson TC, Scardino PT. Some small prostate cancers are nondiploid by nuclear image analysis: correlation of deoxyribonucleic acid ploidy status and pathological features. J Urol. 1994 May; 151(5):1301-7. PMID: 8158775.
      View in: PubMed
    288. Ostrowski ML, Wheeler TM. Paraganglia of the prostate. Location, frequency, and differentiation from prostatic adenocarcinoma. Am J Surg Pathol. 1994 Apr; 18(4):412-20. PMID: 8141432.
      View in: PubMed
    289. Wheeler T, Sollero C, Alderman S, Landen J, Anthony F, Osmond C. Relation between maternal haemoglobin and placental hormone concentrations in early pregnancy. Lancet. 1994 Feb 26; 343(8896):511-3. PMID: 7906760.
      View in: PubMed
    290. Burch D, Metcalfe S, Gallagher G, al-Azzawi F, Wheeler T. Soluble interleukin-2 receptors and CA 125 in ovarian cancer, a longitudinal and cross-sectional study. Eur J Gynaecol Oncol. 1994; 15(5):352-8. PMID: 7828604.
      View in: PubMed
    291. Wheeler TM, Rogers E, Aihara M, Scardino PT, Thompson TC. Apoptotic index as a biomarker in prostatic intraepithelial neoplasia (PIN) and prostate cancer. J Cell Biochem Suppl. 1994; 19:202-7. PMID: 7823593.
      View in: PubMed
    292. Greene DR, Wheeler TM. Clinical relevance of the individual prostate cancer focus. Cancer Invest. 1994; 12(4):425-37. PMID: 8032966.
      View in: PubMed
    293. Aihara M, Wheeler TM, Ohori M, Scardino PT. Heterogeneity of prostate cancer in radical prostatectomy specimens. Urology. 1994 Jan; 43(1):60-6; discussion 66-7. PMID: 8284886.
      View in: PubMed
    294. Bostwick DG, Burke HB, Wheeler TM, Chung LW, Bookstein R, Pretlow TG, Nagle RB, Montironi R, Lieber MM, Veltri RW, et al. The most promising surrogate endpoint biomarkers for screening candidate chemopreventive compounds for prostatic adenocarcinoma in short-term phase II clinical trials. J Cell Biochem Suppl. 1994; 19:283-9. PMID: 7529857.
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    295. Ohori M, Scardino PT, Lapin SL, Seale-Hawkins C, Link J, Wheeler TM. The mechanisms and prognostic significance of seminal vesicle involvement by prostate cancer. Am J Surg Pathol. 1993 Dec; 17(12):1252-61. PMID: 8238732.
      View in: PubMed
    296. Ohori M, Shinohara K, Wheeler TM, Aihara M, Wessels EC, Carter SS, Scardino PT. Ultrasonic detection of non-palpable seminal vesicle invasion: a clinicopathological study. Br J Urol. 1993 Nov; 72(5 Pt 2):799-808. PMID: 7506627.
      View in: PubMed
    297. Good CB, Hruska BM, Wheeler T. Criteria for long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) in adult inpatients and outpatients. Clin Pharm. 1993 Oct; 12(10):780-2. PMID: 8258260.
      View in: PubMed
    298. Ohori M, Wheeler TM, Greene DR, Scardino PT. Comparison of the pathologic features and DNA ploidy value of prostate cancers detectable by sonography and by palpation. Prostate. 1993; 23(4):271-81. PMID: 8259341.
      View in: PubMed
    299. Ghetie V, Wheeler T, Scott D, Uhr JW, Vitetta ES. A CD4-derived peptide carrier blocks acute HIV-1 infection in vitro and binds to gp120 in the presence of Walter-Reed stage 1-6 HIV+ sera. AIDS Res Hum Retroviruses. 1992 Nov; 8(11):1945-8. PMID: 1489581.
      View in: PubMed
    300. Egawa S, Carter SS, Wheeler TM, Scardino PT. Sonographic monitoring of prostate cancer after definitive radiotherapy. Urology. 1992 Sep; 40(3):230-6. PMID: 1523746.
      View in: PubMed
    301. Rosen MA, Goldstone L, Lapin S, Wheeler T, Scardino PT. Frequency and location of extracapsular extension and positive surgical margins in radical prostatectomy specimens. J Urol. 1992 Aug; 148(2 Pt 1):331-7. PMID: 1635129.
      View in: PubMed
    302. Egawa S, Wheeler TM, Greene DR, Scardino PT. Detection of residual prostate cancer after radiotherapy by sonographically guided needle biopsy. Urology. 1992 Apr; 39(4):358-63. PMID: 1373015.
      View in: PubMed
    303. Egawa S, Wheeler TM, Greene DR, Scardino PT. Unusual hyperechoic appearance of prostate cancer on transrectal ultrasonography. Br J Urol. 1992 Feb; 69(2):169-74. PMID: 1311217.
      View in: PubMed
    304. Bostwick DG, Montironi R, Nogle R, Pretlow T, Miller G, Wheeler T, Epstein J, Sakr W. Current and proposed biologic markers in prostate cancer. J Cell Biochem Suppl. 1992; 16H:65-7. PMID: 1289675.
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    305. Greene DR, Wheeler TM, Egawa S, Weaver RP, Scardino PT. Relationship between clinical stage and histological zone of origin in early prostate cancer: morphometric analysis. Br J Urol. 1991 Nov; 68(5):499-509. PMID: 1747726.
      View in: PubMed
    306. Greene DR, Wheeler TM, Egawa S, Dunn JK, Scardino PT. A comparison of the morphological features of cancer arising in the transition zone and in the peripheral zone of the prostate. J Urol. 1991 Oct; 146(4):1069-76. PMID: 1895423.
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    307. Greene DR, Taylor SR, Wheeler TM, Scardino PT. DNA ploidy by image analysis of individual foci of prostate cancer: a preliminary report. Cancer Res. 1991 Aug 1; 51(15):4084-9. PMID: 1855223.
      View in: PubMed
    308. Egawa S, Wheeler TM, Scardino PT. The sonographic appearance of irradiated prostate cancer. Br J Urol. 1991 Aug; 68(2):172-7. PMID: 1884145.
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    309. Egawa S, Greene DR, Flanagan WF, Wheeler TM, Scardino PT. Transrectal ultrasonography in stage A prostate cancer: detection of residual tumor after transurethral resection of prostate. J Urol. 1991 Aug; 146(2):366-71. PMID: 1856933.
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    310. Greene DR, Egawa S, Neerhut G, Flanagan W, Wheeler TM, Scardino PT. The distribution of residual cancer in radical prostatectomy specimens in stage A prostate cancer. J Urol. 1991 Feb; 145(2):324-8; discussion 328-9. PMID: 1988723.
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    311. Truong LD, Mody DR, Cagle PT, Jackson-York GL, Schwartz MR, Wheeler TM. Thymic carcinoma. A clinicopathologic study of 13 cases. Am J Surg Pathol. 1990 Feb; 14(2):151-66. PMID: 1689123.
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    312. Gagel RF, Levy ML, Donovan DT, Alford BR, Wheeler T, Tschen JA. Multiple endocrine neoplasia type 2a associated with cutaneous lichen amyloidosis. Ann Intern Med. 1989 Nov 15; 111(10):802-6. PMID: 2573304.
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    313. Shinohara K, Scardino PT, Carter SS, Wheeler TM. Pathologic basis of the sonographic appearance of the normal and malignant prostate. Urol Clin North Am. 1989 Nov; 16(4):675-91. PMID: 2683298.
      View in: PubMed
    314. Scardino PT, Shinohara K, Wheeler TM, Carter SS. Staging of prostate cancer. Value of ultrasonography. Urol Clin North Am. 1989 Nov; 16(4):713-34. PMID: 2683301.
      View in: PubMed
    315. Wheeler TM. Anatomic considerations in carcinoma of the prostate. Urol Clin North Am. 1989 Nov; 16(4):623-34. PMID: 2815420.
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    316. Egawa S, Carter SS, Wheeler TM, Scardino PT. Ultrasonographic changes in the normal and malignant prostate after definitive radiotherapy. Urol Clin North Am. 1989 Nov; 16(4):741-9. PMID: 2683303.
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    317. Shinohara K, Wheeler TM, Scardino PT. The appearance of prostate cancer on transrectal ultrasonography: correlation of imaging and pathological examinations. J Urol. 1989 Jul; 142(1):76-82. PMID: 2659828.
      View in: PubMed
    318. Donovan DT, Levy ML, Furst EJ, Alford BR, Wheeler T, Tschen JA, Gagel RF. Familial cutaneous lichen amyloidosis in association with multiple endocrine neoplasia type 2A: a new variant. Henry Ford Hosp Med J. 1989; 37(3-4):147-50. PMID: 2576950.
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    319. Meacham RB, Mata JA, Espada R, Wheeler TM, Schum CW, Scardino PT. Testicular metastasis as the first manifestation of colon carcinoma. J Urol. 1988 Sep; 140(3):621-2. PMID: 3411689.
      View in: PubMed
    320. Wheeler TM, Johnson EH, Coughlin D, Greenberg SD. The sensitivity of detection of asbestos bodies in sputa and bronchial washings. Acta Cytol. 1988 Sep-Oct; 32(5):647-50. PMID: 2458660.
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    321. Neerhut GJ, Wheeler T, Cantini M, Scardino PT. Salvage radical prostatectomy for radiorecurrent adenocarcinoma of the prostate. J Urol. 1988 Sep; 140(3):544-9. PMID: 3411670.
      View in: PubMed
    322. Rubenfeld S, Wheeler TM. Thyroid cancer presenting as a hot thyroid nodule: report of a case and review of the literature. Thyroidology. 1988 Apr; (1):63-8. PMID: 2484898.
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    323. Truong LD, Ansari MQ, Ansari SJ, Wheeler TM, Mattioli CM, Gillum D. Acquired cystic kidney disease: occurrence in patients on chronic peritoneal dialysis. Am J Kidney Dis. 1988 Feb; 11(2):192-5. PMID: 3341377.
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    324. Goldfarb R, Pool JL, Wheeler T. Isolated renal artery dissection secondary to medial degeneration. J Urol. 1988 Feb; 139(2):346-7. PMID: 3339739.
      View in: PubMed
    325. Scardino PT, Wheeler TM. Local control of prostate cancer with radiotherapy: frequency and prognostic significance of positive results of postirradiation prostate biopsy. NCI Monogr. 1988; (7):95-103. PMID: 3050543.
      View in: PubMed
    326. Coburn M, Wheeler T, Lipshultz LI. Testicular biopsy. Its use and limitations. Urol Clin North Am. 1987 Aug; 14(3):551-61. PMID: 3617269.
      View in: PubMed
    327. Wheeler TM, Zimmerman TJ. Expulsive choroidal hemorrhage in the glaucoma patient. Ann Ophthalmol. 1987 May; 19(5):165-6. PMID: 3496033.
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    328. Truong LD, Harris L, Mattioli C, Hawkins E, Lee A, Wheeler T, Lane M. Endodermal sinus tumor of the mediastinum. A report of seven cases and review of the literature. Cancer. 1986 Aug 1; 58(3):730-9. PMID: 2425923.
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    329. Harris RL, Lawrie GM, Wheeler TM, Rex JH, Sarosi GA, Jacob MC, Bradshaw MW, Williams TW. Successful management of Histoplasma capsulatum infection of an abdominal aortic aneurysm. J Vasc Surg. 1986 Apr; 3(4):649-51. PMID: 3959262.
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    330. Scardino PT, Frankel JM, Wheeler TM, Meacham RB, Hoffman GS, Seale C, Wilbanks JH, Easley J, Carlton CE. The prognostic significance of post-irradiation biopsy results in patients with prostatic cancer. J Urol. 1986 Mar; 135(3):510-6. PMID: 3944896.
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    331. Rex JH, Harris RL, Wheeler T, White M, Bradshaw W, Williams TW. Granulomatous disease complicating hairy cell leukemia. Tex Med. 1985 Jul; 81(7):31-3. PMID: 4035595.
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    332. Scardino PT, Wheeler TM. Prostatic biopsy after irradiation therapy for prostatic cancer. Urology. 1985 Feb; 25(2 Suppl):39-46. PMID: 3918375.
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    333. Riccardi VM, Wheeler TM, Pickard LR, King B. The pathophysiology of neurofibromatosis. II. Angiosarcoma as a complication. Cancer Genet Cytogenet. 1984 Jul; 12(3):275-80. PMID: 6426776.
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    334. Font RL, Wheeler TM, Boniuk M. Intravascular papillary endothelial hyperplasia of the orbit and ocular adnexa. A report of five cases. Arch Ophthalmol. 1983 Nov; 101(11):1731-6. PMID: 6685471.
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    335. Smedley H, Katrak M, Sikora K, Wheeler T. Neurological effects of recombinant human interferon. Br Med J (Clin Res Ed). 1983 Jan 22; 286(6361):262-4. PMID: 6402063; PMCID: PMC1546481.
    336. Ozanne B, Wheeler T, Zack J, Smith G, Dale B. Transforming gene of a human leukaemia cell is unrelated to the expressed tumour virus related gene of the cell. Nature. 1982 Oct 21; 299(5885):744-7. PMID: 7121605.
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    337. Rubenfeld S, Wheeler TM, Spjut HJ. Fine-needle aspiration biopsy of thyroid nodules. Tex Med. 1982 Sep; 78(9):41-4. PMID: 7147200.
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    338. Rice L, Abramson SL, Laughter AH, Wheeler TM, Twomey JJ. Angioimmunoblastic lymphadenopathy with hypogammaglobulinemia. Possible role of monocyte suppression. Am J Med. 1982 Jun; 72(6):998-1004. PMID: 6211980.
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    339. Panko WB, Mattioli CA, Wheeler TM. Lack of correlation of a histochemical method for estrogen receptors analysis with the biochemical assay results. Cancer. 1982 May 15; 49(10):2148-52. PMID: 7074530.
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    340. Rice L, Shenkenberg T, Lynch EC, Wheeler TM. Granulomatous infections complicating hairy cell leukemia. Cancer. 1982 May 1; 49(9):1924-8. PMID: 7074589.
      View in: PubMed
    341. Zimmerman TJ, Wheeler TM. Miotics: side effects and ways to avoid them. Ophthalmology. 1982 Jan; 89(1):76-80. PMID: 7070779.
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    342. Spittle MF, Bates TD, Kitchen G, Nicol NT, Wheeler T, Edelstyn G, MacRae KD, Ostrowski MJ. Combination chemotherapy in advanced breast cancer. A report of the Working Party of the Multicentre Cancer Chemotherapy Group. Clin Oncol. 1980 Jun; 6(2):153-7. PMID: 7408282.
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    343. Wheeler TM, McGavran MH. Myospherulosis--further observations. Am J Clin Pathol. 1980 May; 73(5):685-6. PMID: 7377136.
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    344. Wheeler TM, Sessions RB, McGavran MH. Myospherulosis: a preventable iatrogenic nasal and paranasal entity. Arch Otolaryngol. 1980 May; 106(5):272-4. PMID: 6989350.
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    345. Edelstyn GA, Bates TD, Brinkley D, MacRae KD, Spittle MF, Wheeler T. Comparison of 5-day and 2-day cyclical combination chemotherapy in advanced breast cancer. Clin Oncol. 1979 Jun; 5(2):163-7. PMID: 466894.
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    346. Edelstyn GA, Bates T, Brinkley D, Kitchen G, MacRae KD, Nicol NT, Spittle M, Wheeler T. Multimodal therapy from stage-II breast cancer. Lancet. 1978 Nov 18; 2(8099):1092. PMID: 82102.
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    347. Kamen RI, Wheeler T, Smith AE. Polyoma virus high molecular weight nuclear RNA codes for capsid protein VP2 in vitro. Virology. 1978 Sep; 89(2):461-74. PMID: 213877.
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    348. Edelstyn GA, Bates IS, Brinkley D, MacRae KD, Spittle H, Wheeler T. Four drug combination cytotoxic chemotherapy following surgery for breast cancer. Recent Results Cancer Res. 1978; 68:109-12. PMID: 752851.
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    349. Edelstyn GA, Bates TD, Brinkley D, MacRae KD, Spittle MF, Wheeler T. Comparison of 5-day, 1-day, and 2-day cyclical combination chemotherapy in advanced breast cancer. Lancet. 1975 Aug 2; 2(7927):209-11. PMID: 51964.
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