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KARL-DIMITER BISSIG

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Cell & Gene Therapy
    DivisionCenter for Cell & Gene Therapy


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Pankowicz FP, Barzi M, Legras X, Hubert L, Mi T, Tomolonis JA, Ravishankar M, Sun Q, Yang D, Borowiak M, Sumazin P, Elsea SH, Bissig-Choisat B, Bissig KD. Reprogramming metabolic pathways in vivo with CRISPR/Cas9 genome editing to treat hereditary tyrosinaemia. Nat Commun. 2016; 7:12642. PMID: 27572891.
      View in: PubMed
    2. Bissig KD, Paust S, Barzi M. Liver is liver and blood is blood, and finally the twain have met. J Hepatol. 2016 May 21. PMID: 27221221.
      View in: PubMed
    3. Bissig-Choisat B, Kettlun-Leyton C, Legras XD, Zorman B, Barzi M, Chen LL, Amin MD, Huang YH, Pautler RG, Hampton OA, Prakash MM, Yang D, Borowiak M, Muzny D, Doddapaneni H, Hu J, Shi Y, Gaber WM, John Hicks M, Thompson PA, Lu Y, Mills GB, Finegold M, Goss JA, Williams Parsons D, Vasudevan SA, Sumazin P, Lopez-Terrada D, Bissig KD. Novel Patient-Derived Xenograft and Cell Line Models for Therapeutic Testing of Pediatric Liver Cancer. J Hepatol. 2016 Apr 23. PMID: 27117591.
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    4. Billioud G, Kruse RL, Carrillo M, Whitten-Bauer C, Gao D, Kim A, Chen L, McCaleb ML, Crosby JR, Hamatake R, Hong Z, Garaigorta U, Swayze E, Bissig KD, Wieland S. In vivo reduction of hepatitis B virus antigenemia and viremia by antisense oligonucleotides. J Hepatol. 2016 Apr; 64(4):781-9. PMID: 26658683.
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    5. Shih YM, Sun CP, Chou HH, Wu TH, Chen CC, Wu PY, Enya Chen YC, Bissig KD, Tao MH. Combinatorial RNA Interference Therapy Prevents Selection of Pre-existing HBV Variants in Human Liver Chimeric Mice. Sci Rep. 2015; 5:15259. PMID: 26482836.
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    6. Bissig-Choisat B, Wang L, Legras X, Saha PK, Chen L, Bell P, Pankowicz FP, Hill MC, Barzi M, Leyton CK, Leung HC, Kruse RL, Himes RW, Goss JA, Wilson JM, Chan L, Lagor WR, Bissig KD. Development and rescue of human familial hypercholesterolaemia in a xenograft mouse model. Nat Commun. 2015; 6:7339. PMID: 26081744.
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    7. Lin F, Marcelo KL, Rajapakshe K, Coarfa C, Dean A, Wilganowski N, Robinson H, Sevick E, Bissig KD, Goldie LC, Means AR, York B. The camKK2/camKIV relay is an essential regulator of hepatic cancer. Hepatology. 2015 Aug; 62(2):505-20. PMID: 25847065.
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    8. Bissig KD, Grompe M. Response to "Can 'humanized' mice improve drug development in the 21st century?". Trends Pharmacol Sci. 2013 Aug; 34(8):425. PMID: 23876405.
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    9. Goldman O, Han S, Sourisseau M, Sourrisseau M, Dziedzic N, Hamou W, Corneo B, D'Souza S, Sato T, Kotton DN, Bissig KD, Kalir T, Jacobs A, Evans T, Evans MJ, Gouon-Evans V. KDR identifies a conserved human and murine hepatic progenitor and instructs early liver development. Cell Stem Cell. 2013 Jun 6; 12(6):748-60. PMID: 23746980; PMCID: PMC3922205.
    10. Ruiz S, Panopoulos AD, Herrerías A, Bissig KD, Lutz M, Berggren WT, Verma IM, Izpisua Belmonte JC. A high proliferation rate is required for cell reprogramming and maintenance of human embryonic stem cell identity. Curr Biol. 2011 Jan 11; 21(1):45-52. PMID: 21167714; PMCID: PMC3034649.
    11. Bissig KD, Wieland SF, Tran P, Isogawa M, Le TT, Chisari FV, Verma IM. Human liver chimeric mice provide a model for hepatitis B and C virus infection and treatment. J Clin Invest. 2010 Mar; 120(3):924-30. PMID: 20179355; PMCID: PMC2827952.
    12. Bissig KD, Le TT, Woods NB, Verma IM. Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model. Proc Natl Acad Sci U S A. 2007 Dec 18; 104(51):20507-11. PMID: 18077355; PMCID: PMC2154461.
    13. Bissig KD, Honer M, Zimmermann K, Summer KH, Solioz M. Whole animal copper flux assessed by positron emission tomography in the Long-Evans cinnamon rat--a feasibility study. Biometals. 2005 Feb; 18(1):83-8. PMID: 15865413.
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    14. Bissig KD, Zimmermann A, Bernasch D, Furrer H, Dufour JF. Herpes simplex virus hepatitis 4 years after liver transplantation. J Gastroenterol. 2003; 38(10):1005-8. PMID: 14614611.
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    15. Bissig KD, Voegelin TC, Solioz M. Tetrathiomolybdate inhibition of the Enterococcus hirae CopB copper ATPase. FEBS Lett. 2001 Nov 2; 507(3):367-70. PMID: 11696373.
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    16. Multhaup G, Strausak D, Bissig KD, Solioz M. Interaction of the CopZ copper chaperone with the CopA copper ATPase of Enterococcus hirae assessed by surface plasmon resonance. Biochem Biophys Res Commun. 2001 Oct 19; 288(1):172-7. PMID: 11594769.
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    17. Bissig KD, Wunderli-Ye H, Duda PW, Solioz M. Structure-function analysis of purified Enterococcus hirae CopB copper ATPase: effect of Menkes/Wilson disease mutation homologues. Biochem J. 2001 Jul 1; 357(Pt 1):217-23. PMID: 11415452; PMCID: PMC1221944.
    18. Bissig KD, La Fontaine S, Mercer JF, Solioz M. Expression of the human Menkes ATPase in Xenopus laevis oocytes. Biol Chem. 2001 Apr; 382(4):711-4. PMID: 11405236.
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    19. Bissig KD, Marti U, Solioz M, Forestier M, Zimmermann H, Lüthi M, Reichen J. Epidermal growth factor is decreased in liver of rats with biliary cirrhosis but does not act as paracrine growth factor immediately after hepatectomy. J Hepatol. 2000 Aug; 33(2):275-81. PMID: 10952245.
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    20. Solioz M, Bissig KD. [How (deficient) copper causes illness]. Schweiz Med Wochenschr. 1998 Aug 4; 128(31-32):1175-80. PMID: 9738276.
      View in: PubMed
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