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VINOD VIJAYAN

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address2002 Holcombe Blvd.
Houston TX 77030
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Physiology & Biophysics
    DivisionMolecular Physiology & Biophysics

    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Hematology & Oncology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Wang R, Stone RL, Kaelber JT, Rochat RH, Nick AM, Vijayan KV, Afshar-Kharghan V, Schmid MF, Dong JF, Sood AK, Chiu W. Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer. Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46):14266-14271. PMID: 26578771.
      View in: PubMed
    2. Lam FW, Vijayan KV, Rumbaut RE. Platelets and Their Interactions with Other Immune Cells. Compr Physiol. 2015 Jul 1; 5(3):1265-80. PMID: 26140718.
      View in: PubMed
    3. Vijayan KV. DGKE disruption ditches complement and drives p38 signaling. Blood. 2015 Feb 5; 125(6):898-9. PMID: 25655457.
      View in: PubMed
    4. Khatlani T, Pradhan S, Da Q, Gushiken FC, Bergeron AL, Langlois KW, Molkentin JD, Rumbaut RE, Vijayan KV. The ? isoform of the catalytic subunit of protein phosphatase 2B restrains platelet function by suppressing outside-in ?II b ?3 integrin signaling. J Thromb Haemost. 2014 Dec; 12(12):2089-101. PMID: 25330904; PMCID: PMC4268338.
    5. Da Q, Behymer M, Correa JI, Vijayan KV, Cruz MA. Platelet adhesion involves a novel interaction between vimentin and von Willebrand factor under high shear stress. Blood. 2014 Apr 24; 123(17):2715-21. PMID: 24642750; PMCID: PMC3999756.
    6. Nascimbene A, Hernandez R, George JK, Parker A, Bergeron AL, Pradhan S, Vijayan KV, Civitello A, Simpson L, Nawrot M, Lee VV, Mallidi HR, Delgado RM, Dong JF, Frazier OH. Association between cell-derived microparticles and adverse events in patients with nonpulsatile left ventricular assist devices. J Heart Lung Transplant. 2014 May; 33(5):470-7. PMID: 24656391; PMCID: PMC3992167.
    7. Pradhan S, Vijayan KV. Lipid rafts contribute to agonist-induced serine/threonine phosphatase activation and platelet aggregation. J Thromb Haemost. 2013 Aug; 11(8):1612-5. PMID: 23789860; PMCID: PMC3749069.
    8. Zhou Z, Gushiken FC, Bolgiano D, Salsbery BJ, Aghakasiri N, Jing N, Wu X, Vijayan KV, Rumbaut RE, Adachi R, Lopez JA, Dong JF. Signal transducer and activator of transcription 3 (STAT3) regulates collagen-induced platelet aggregation independently of its transcription factor activity. Circulation. 2013 Jan 29; 127(4):476-85. PMID: 23266857; PMCID: PMC4472638.
    9. Alrehani N, Pradhan S, Khatlani T, Kailasam L, Vijayan KV. Distinct roles for the ? , ? and ?1 isoforms of protein phosphatase 1 in the outside-in ?IIb?3 integrin signalling-dependent functions. Thromb Haemost. 2013 Jan; 109(1):118-26. PMID: 23197154; PMCID: PMC3749075.
    10. Mayanglambam A, Bhavanasi D, Vijayan KV, Kunapuli SP. Differential dephosphorylation of the protein kinase C-zeta (PKC?) in an integrin ?IIb?3-dependent manner in platelets. Biochem Pharmacol. 2011 Sep 1; 82(5):505-13. PMID: 21645497; PMCID: PMC3148309.
    11. Matijevic N, Wang YW, Kostousov V, Wade CE, Vijayan KV, Holcomb JB. Decline in platelet microparticles contributes to reduced hemostatic potential of stored plasma. Thromb Res. 2011 Jul; 128(1):35-41. PMID: 21421259; PMCID: PMC3109134.
    12. Pradhan S, Alrehani N, Patel V, Khatlani T, Vijayan KV. Cross-talk between serine/threonine protein phosphatase 2A and protein tyrosine phosphatase 1B regulates Src activation and adhesion of integrin ?IIb?3 to fibrinogen. J Biol Chem. 2010 Sep 17; 285(38):29059-68. PMID: 20615878; PMCID: PMC2937937.
    13. Auton M, Sowa KE, Smith SM, Sedlák E, Vijayan KV, Cruz MA. Destabilization of the A1 domain in von Willebrand factor dissociates the A1A2A3 tri-domain and provokes spontaneous binding to glycoprotein Ibalpha and platelet activation under shear stress. J Biol Chem. 2010 Jul 23; 285(30):22831-9. PMID: 20498367; PMCID: PMC2906274.
    14. Gushiken FC, Hyojeong H, Pradhan S, Langlois KW, Alrehani N, Cruz MA, Rumbaut RE, Vijayan KV. The catalytic subunit of protein phosphatase 1 gamma regulates thrombin-induced murine platelet alpha(IIb)beta(3) function. PLoS One. 2009; 4(12):e8304. PMID: 20016849; PMCID: PMC2788699.
    15. Nolasco LH, Gushiken FC, Turner NA, Khatlani TS, Pradhan S, Dong JF, Moake JL, Vijayan KV. Protein phosphatase 2B inhibition promotes the secretion of von Willebrand factor from endothelial cells. J Thromb Haemost. 2009 Jun; 7(6):1009-18. PMID: 19344364.
      View in: PubMed
    16. Bynagari YS, Nagy B, Tuluc F, Bhavaraju K, Kim S, Vijayan KV, Kunapuli SP. Mechanism of activation and functional role of protein kinase Ceta in human platelets. J Biol Chem. 2009 May 15; 284(20):13413-21. PMID: 19286657.
      View in: PubMed
    17. Ball C, Vijayan KV, Nguyen T, Anthony K, Bray PF, Essex DW, Dong JF. Glutathione regulates integrin alpha(IIb)beta(3)-mediated cell adhesion under flow conditions. Thromb Haemost. 2008 Nov; 100(5):857-63. PMID: 18989530.
      View in: PubMed
    18. Gushiken FC, Patel V, Liu Y, Pradhan S, Bergeron AL, Peng Y, Vijayan KV. Protein phosphatase 2A negatively regulates integrin alpha(IIb)beta(3) signaling. J Biol Chem. 2008 May 9; 283(19):12862-9. PMID: 18334487; PMCID: PMC2442329.
    19. Vijayan KV, Bray PF. Molecular mechanisms of prothrombotic risk due to genetic variations in platelet genes: Enhanced outside-in signaling through the Pro33 variant of integrin beta3. Exp Biol Med (Maywood). 2006 May; 231(5):505-13. PMID: 16636298.
      View in: PubMed
    20. Vijayan KV, Liu Y, Souza S, Thiagarajan P, Bray PF. Fibrinogen and prothrombin binding is enhanced to the Pro33 isoform of purified integrin alphaIIbbeta3. J Thromb Haemost. 2006 Apr; 4(4):905-6. PMID: 16634766.
      View in: PubMed
    21. Vijayan KV, Liu Y, Sun W, Ito M, Bray PF. The Pro33 isoform of integrin beta3 enhances outside-in signaling in human platelets by regulating the activation of serine/threonine phosphatases. J Biol Chem. 2005 Jun 10; 280(23):21756-62. PMID: 15826939.
      View in: PubMed
    22. Vijayan KV, Liu Y, Li TT, Bray PF. Protein phosphatase 1 associates with the integrin alphaIIb subunit and regulates signaling. J Biol Chem. 2004 Aug 6; 279(32):33039-42. PMID: 15205468.
      View in: PubMed
    23. Vijayan KV, Huang TC, Liu Y, Bernardo A, Dong JF, Goldschmidt-Clermont PJ, Alevriadou BR, Bray PF. Shear stress augments the enhanced adhesive phenotype of cells expressing the Pro33 isoform of integrin beta3. FEBS Lett. 2003 Apr 10; 540(1-3):41-6. PMID: 12681480.
      View in: PubMed
    24. Sajid M, Vijayan KV, Souza S, Bray PF. PlA polymorphism of integrin beta 3 differentially modulates cellular migration on extracellular matrix proteins. Arterioscler Thromb Vasc Biol. 2002 Dec 1; 22(12):1984-9. PMID: 12482823.
      View in: PubMed
    25. Vijayan KV, Liu Y, Dong JF, Bray PF. Enhanced activation of mitogen-activated protein kinase and myosin light chain kinase by the Pro33 polymorphism of integrin beta 3. J Biol Chem. 2003 Feb 7; 278(6):3860-7. PMID: 12460991.
      View in: PubMed
    26. Nealen ML, Vijayan KV, Bolton E, Bray PF. Human platelets contain a glycosylated estrogen receptor beta. Circ Res. 2001 Mar 2; 88(4):438-42. PMID: 11230112.
      View in: PubMed
    27. Khetawat G, Faraday N, Nealen ML, Vijayan KV, Bolton E, Noga SJ, Bray PF. Human megakaryocytes and platelets contain the estrogen receptor beta and androgen receptor (AR): testosterone regulates AR expression. Blood. 2000 Apr 1; 95(7):2289-96. PMID: 10733498.
      View in: PubMed
    28. Vijayan KV, Goldschmidt-Clermont PJ, Roos C, Bray PF. The Pl(A2) polymorphism of integrin beta(3) enhances outside-in signaling and adhesive functions. J Clin Invest. 2000 Mar; 105(6):793-802. PMID: 10727448.
      View in: PubMed
    29. Vijayan KV, Advani SH, Zingde SM. Chronic myeloid leukemic granulocytes exhibit reduced and altered binding to P-selectin: modification in the CD15 antigens and sialylation. Leuk Res. 1997 Jan; 21(1):59-65. PMID: 9029187.
      View in: PubMed
    30. Vijayan VK, Zingde SM. Heat-treated bovine serum albumin is a better blocking reagent for adhesion studies. Biotechniques. 1995 Mar; 18(3):430-2. PMID: 7779392.
      View in: PubMed
    31. Vijayan VK, Advani SH, Zingde SM. Chronic myeloid leukemic granulocytes exhibit decreased adhesion to fibronectin. Leuk Res. 1994 Dec; 18(12):877-9. PMID: 7996867.
      View in: PubMed
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