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VIJAY K. YECHOOR

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressONE BAYLOR PLAZA
HOUSTON TX 77030
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Goo YH, Yechoor VK, Paul A. Transcriptional profiling of foam cells in response to hypercholesterolemia. Genom Data. 2016 Sep; 9:37-9. PMID: 27408807; PMCID: PMC4925893.
    2. Goo YH, Son SH, Yechoor VK, Paul A. Transcriptional Profiling of Foam Cells Reveals Induction of Guanylate-Binding Proteins Following Western Diet Acceleration of Atherosclerosis in the Absence of Global Changes in Inflammation. J Am Heart Assoc. 2016 Apr; 5(4). PMID: 27091181; PMCID: PMC4859273.
    3. Lee J, Liu R, de Jesus D, Kim BS, Ma K, Moulik M, Yechoor V. Circadian control of ?-cell function and stress responses. Diabetes Obes Metab. 2015 Sep; 17 Suppl 1:123-33. PMID: 26332977.
      View in: PubMed
    4. Nam D, Yechoor VK, Ma K. Molecular clock integration of brown adipose tissue formation and function. Adipocyte. 2016 Apr-Jun; 5(2):243-50. PMID: 27385482; PMCID: PMC4916866.
    5. Li R, Buras E, Lee J, Liu R, Liu V, Espiritu C, Ozer K, Thompson B, Nally L, Yuan G, Oka K, Chang B, Samson S, Yechoor V, Chan L. Gene therapy with neurogenin3, betacellulin and SOCS1 reverses diabetes in NOD mice. Gene Ther. 2015 Nov; 22(11):876-82. PMID: 26172077.
      View in: PubMed
    6. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. Erratum. PD-L1-Driven Tolerance Protects Neurogenin3-Induced Islet Neogenesis to Reverse Established Type 1 Diabetes in NOD Mice. Diabetes 2015;64:529-540. Diabetes. 2015 Jul; 64(7):2685. PMID: 26106199.
      View in: PubMed
    7. Nam D, Chatterjee S, Yin H, Liu R, Lee J, Yechoor VK, Ma K. Novel Function of Rev-erb? in Promoting Brown Adipogenesis. Sci Rep. 2015; 5:11239. PMID: 26058812.
      View in: PubMed
    8. Nam D, Guo B, Chatterjee S, Chen MH, Nelson D, Yechoor VK, Ma K. The adipocyte clock controls brown adipogenesis through the TGF-? and BMP signaling pathways. J Cell Sci. 2015 May 1; 128(9):1835-47. PMID: 25749863; PMCID: PMC4446734.
    9. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice. Diabetes. 2015 Feb; 64(2):529-40. PMID: 25332429; PMCID: PMC4303975.
    10. Lee J, Moulik M, Fang Z, Saha P, Zou F, Xu Y, Nelson DL, Ma K, Moore DD, Yechoor VK. Bmal1 and ?-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced ?-cell failure in mice. Mol Cell Biol. 2013 Jun; 33(11):2327-38. PMID: 23547261; PMCID: PMC3648066.
    11. Chatterjee S, Nam D, Guo B, Kim JM, Winnier GE, Lee J, Berdeaux R, Yechoor VK, Ma K. Brain and muscle Arnt-like 1 is a key regulator of myogenesis. J Cell Sci. 2013 May 15; 126(Pt 10):2213-24. PMID: 23525013; PMCID: PMC3672937.
    12. Dixit SS, Wang T, Manzano EJ, Yoo S, Lee J, Chiang DY, Ryan N, Respress JL, Yechoor VK, Wehrens XH. Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance. PLoS One. 2013; 8(3):e58655. PMID: 23516528; PMCID: PMC3596297.
    13. Li R, Oka K, Yechoor V. Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer. J Vis Exp. 2012; (68). PMID: 23093064; PMCID: PMC3490299.
    14. Guo B, Chatterjee S, Li L, Kim JM, Lee J, Yechoor VK, Minze LJ, Hsueh W, Ma K. The clock gene, brain and muscle Arnt-like 1, regulates adipogenesis via Wnt signaling pathway. FASEB J. 2012 Aug; 26(8):3453-63. PMID: 22611086.
      View in: PubMed
    15. Poungvarin N, Lee JK, Yechoor VK, Li MV, Assavapokee T, Suksaranjit P, Thepsongwajja JJ, Saha PK, Oka K, Chan L. Carbohydrate response element-binding protein (ChREBP) plays a pivotal role in beta cell glucotoxicity. Diabetologia. 2012 Jun; 55(6):1783-96. PMID: 22382520; PMCID: PMC4010252.
    16. Chen W, Chang B, Saha P, Hartig SM, Li L, Reddy VT, Yang Y, Yechoor V, Mancini MA, Chan L. Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation. Mol Cell Biol. 2012 Mar; 32(6):1099-111. PMID: 22269949; PMCID: PMC3295006.
    17. Lee J, Kim MS, Li R, Liu VY, Fu L, Moore DD, Ma K, Yechoor VK. Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in ?-cells. Islets. 2011 Nov-Dec; 3(6):381-8. PMID: 22045262; PMCID: PMC3329519.
    18. Park YJ, Kim SC, Kim J, Anakk S, Lee JM, Tseng HT, Yechoor V, Park J, Choi JS, Jang HC, Lee KU, Novak CM, Moore DD, Lee YK. Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner. J Lipid Res. 2011 Dec; 52(12):2234-44. PMID: 21949050; PMCID: PMC3220290.
    19. Yang Y, Chang BH, Yechoor V, Chen W, Li L, Tsai MJ, Chan L. The Kr├╝ppel-like zinc finger protein GLIS3 transactivates neurogenin 3 for proper fetal pancreatic islet differentiation in mice. Diabetologia. 2011 Oct; 54(10):2595-605. PMID: 21786021; PMCID: PMC3184604.
    20. Yechoor V, Chan L. Minireview: beta-cell replacement therapy for diabetes in the 21st century: manipulation of cell fate by directed differentiation. Mol Endocrinol. 2010 Aug; 24(8):1501-11. PMID: 20219891; PMCID: PMC2940465.
    21. Yechoor V, Liu V, Paul A, Lee J, Buras E, Ozer K, Samson S, Chan L. Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice. Endocrinology. 2009 Nov; 150(11):4863-73. PMID: 19819964; PMCID: PMC2775983.
    22. Chen W, Yechoor VK, Chang BH, Li MV, March KL, Chan L. The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation. Endocrinology. 2009 Oct; 150(10):4552-61. PMID: 19574402; PMCID: PMC2754678.
    23. Yechoor V, Liu V, Espiritu C, Paul A, Oka K, Kojima H, Chan L. Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev Cell. 2009 Mar; 16(3):358-73. PMID: 19289082; PMCID: PMC2676438.
    24. Samson SL, Gonzalez EV, Yechoor V, Bajaj M, Oka K, Chan L. Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model. Mol Ther. 2008 Nov; 16(11):1805-12. PMID: 18781141; PMCID: PMC2582376.
    25. Paul A, Chang BH, Li L, Yechoor VK, Chan L. Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis. Circ Res. 2008 Jun 20; 102(12):1492-501. PMID: 18483409; PMCID: PMC2773502.
    26. Paul A, Yechoor V, Raja R, Li L, Chan L. Microarray gene profiling of laser-captured cells: a new tool to study atherosclerosis in mice. Atherosclerosis. 2008 Oct; 200(2):257-63. PMID: 18289551; PMCID: PMC2613781.
    27. Tseng YH, Butte AJ, Kokkotou E, Yechoor VK, Taniguchi CM, Kriauciunas KM, Cypess AM, Niinobe M, Yoshikawa K, Patti ME, Kahn CR. Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin. Nat Cell Biol. 2005 Jun; 7(6):601-11. PMID: 15895078.
      View in: PubMed
    28. Niendorf ER, Parker JA, Yechoor V, Garber JR, Boiselle PM. Thymic hyperplasia in thyroid cancer patients. J Thorac Imaging. 2005 Feb; 20(1):1-4. PMID: 15729115.
      View in: PubMed
    29. Yechoor V, Chan L. Gene therapy progress and prospects: gene therapy for diabetes mellitus. Gene Ther. 2005 Jan; 12(2):101-7. PMID: 15496957.
      View in: PubMed
    30. Yechoor VK, Patti ME, Ueki K, Laustsen PG, Saccone R, Rauniyar R, Kahn CR. Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16525-30. PMID: 15546994; PMCID: PMC534529.
    31. Paul A, Ko KW, Li L, Yechoor V, McCrory MA, Szalai AJ, Chan L. C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2004 Feb 10; 109(5):647-55. PMID: 14744975.
      View in: PubMed
    32. Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, Sharma S, O'Connell P, Taegtmeyer H, Chan L. Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile. Diabetes. 2003 Nov; 52(11):2666-74. PMID: 14578284.
      View in: PubMed
    33. Yechoor VK, Patti ME, Saccone R, Kahn CR. Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice. Proc Natl Acad Sci U S A. 2002 Aug 6; 99(16):10587-92. PMID: 12149437; PMCID: PMC124982.
    34. Yechoor VK, Shandera WX, Rodriguez P, Cate TR. Tuberculous meningitis among adults with and without HIV infection. Experience in an urban public hospital. Arch Intern Med. 1996 Aug 12-26; 156(15):1710-6. PMID: 8694670.
      View in: PubMed
    35. Uppal SS, Pande I, Kakkar R, Yechoor V, Kumar A, Saxena A, Wali JP, Malaviya AN. Infective endocarditis in a case of systemic lupus erythematosus. J Assoc Physicians India. 1993 Jul; 41(7):470. PMID: 8300503.
      View in: PubMed
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