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JED GREGORY NUCHTERN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
Address6701 Fannin St., Suite 1210
HOUSTON TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Administration


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    Dr. Jed G. Nuchtern leads a collaborative research program that includes translational and clinical research on developing new treatments for pediatric solid tumors, particularly neuroblastoma. The primary focus in his laboratory is identifying new targets for neuroblastoma therapy. Bioinformatic studies have identified several proteins whose expression is increased in high-risk neuroblastoma tumors. The laboratory has validated these findings and demonstrated that blocking the expression of these target proteins decreases tumor growth and progression. Current research seeks to identify the pathways through which these molecules affect tumor progression.

    In addition to these translational studies, Dr. Nuchtern is involved in clinical research on neuroblastoma in infants. Through the Children’s Oncology Group, he designed and implemented a prospective international study investigating the safety and efficacy of expectant observation as the primary treatment modality for infants with low risk adrenal tumors.

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    Neuroblastoma
    Tumor progression
    Cancer target discovery


    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Yu YR, Abbas PI, Smith CM, Carberry KE, Ren H, Patel B, Nuchtern JG, Lopez ME. Time-driven activity-based costing to identify opportunities for cost reduction in pediatric appendectomy. J Pediatr Surg. 2016 Sep 15. PMID: 27697316.
      View in: PubMed
    2. Rojas Y, Jaramillo S, Lyons K, Mahmood N, Wu MF, Liu H, Vasudevan SA, Guillerman RP, Louis CU, Russell HV, Nuchtern JG, Kim ES. The optimal timing of surgical resection in high-risk neuroblastoma. J Pediatr Surg. 2016 Jun 7. PMID: 27318861.
      View in: PubMed
    3. Richards MK, Dahl JP, Gow K, Goldin AB, Doski J, Goldfarb M, Nuchtern J, Langer M, Beierle EA, Vasudevan S, Hawkins DS, Parikh SR. Factors Associated With Mortality in Pediatric vs Adult Nasopharyngeal Carcinoma. JAMA Otolaryngol Head Neck Surg. 2016 Mar 1; 142(3):217-22. PMID: 26769566.
      View in: PubMed
    4. Carpenter JL, Fallon SC, Swartz SJ, Minifee PK, Cass DL, Nuchtern JG, Pimpalwar AP, Brandt ML. Outcomes after peritoneal dialysis catheter placement. J Pediatr Surg. 2016 May; 51(5):730-3. PMID: 26936290.
      View in: PubMed
    5. Jaramillo S, Rojas Y, Slater BJ, Baker ML, Hicks MJ, Muscal JA, Vece TJ, Wesson DE, Nuchtern JG. Childhood and adolescent tracheobronchial mucoepidermoid carcinoma (MEC): a case-series and review of the literature. Pediatr Surg Int. 2016 Apr; 32(4):417-24. PMID: 26790674.
      View in: PubMed
    6. Bagatell R, McHugh K, Naranjo A, Van Ryn C, Kirby C, Brock P, Lyons KA, States LJ, Rojas Y, Miller A, Volchenboum SL, Simon T, Krug B, Sarnacki S, Valteau-Couanet D, von Schweinitz D, Kammer B, Granata C, Pio L, Park JR, Nuchtern J. Assessment of Primary Site Response in Children With High-Risk Neuroblastoma: An International Multicenter Study. J Clin Oncol. 2016 Mar 1; 34(7):740-6. PMID: 26755515; PMCID: PMC4872026 [Available on 12/01/16].
    7. Poles GC, Clark DE, Mayo SW, Beierle EA, Goldfarb M, Gow KW, Goldin A, Doski JJ, Nuchtern JG, Vasudevan SA, Langer M. Colorectal carcinoma in pediatric patients: A comparison with adult tumors, treatment and outcomes from the National Cancer Database. J Pediatr Surg. 2016 Jul; 51(7):1061-6. PMID: 26703433.
      View in: PubMed
    8. Roy A, Kumar V, Zorman B, Fang E, Haines KM, Doddapaneni H, Hampton OA, White S, Bavle AA, Patel NR, Eldin KW, John Hicks M, Rakheja D, Leavey PJ, Skapek SX, Amatruda JF, Nuchtern JG, Chintagumpala MM, Wheeler DA, Plon SE, Sumazin P, Parsons DW. Recurrent internal tandem duplications of BCOR in clear cell sarcoma of the kidney. Nat Commun. 2015; 6:8891. PMID: 26573325.
      View in: PubMed
    9. Shi Y, Geller JI, Ma IT, Chavan RS, Masand PM, Towbin AJ, Chintagumpala M, Nuchtern JG, Tiao GM, Thompson PA, Vasudevan SA. Relapsed hepatoblastoma confined to the lung is effectively treated with pulmonary metastasectomy. J Pediatr Surg. 2016 Apr; 51(4):525-9. PMID: 26607968.
      View in: PubMed
    10. Abbas PI, Zamora IJ, Elder SC, Lee TC, Nuchtern JG. Impact of the surgeon of the week system in an academic pediatric surgery practice. J Pediatr Surg. 2016 Apr; 51(4):634-8. PMID: 26589185.
      View in: PubMed
    11. Techavichit P, Hicks MJ, López-Terrada DH, Quintanilla NM, Guillerman RP, Sarabia SF, Sayeed H, Nuchtern JG, Paulino AC, Muscal JA, Okcu MF, Chintagumpala M. Mucoepidermoid Carcinoma in Children: A Single Institutional Experience. Pediatr Blood Cancer. 2016 Jan; 63(1):27-31. PMID: 26221861.
      View in: PubMed
    12. Felsted AE, Shi Y, Masand PM, Nuchtern JG, Goss JA, Vasudevan SA. Intraoperative ultrasound for liver tumor resection in children. J Surg Res. 2015 Oct; 198(2):418-23. PMID: 25940155.
      View in: PubMed
    13. Shi Y, Felsted AE, Masand PM, Mothner BA, Nuchtern JG, Rodriguez JR, Vasudevan SA. Congenital left paraduodenal hernia causing chronic abdominal pain and abdominal catastrophe. Pediatrics. 2015 Apr; 135(4):e1067-71. PMID: 25802350.
      View in: PubMed
    14. Fallon SC, Hicks MJ, Carpenter JL, Vasudevan SA, Nuchtern JG, Cass DL. Management of appendiceal carcinoid tumors in children. J Surg Res. 2015 Oct; 198(2):384-7. PMID: 25891670.
      View in: PubMed
    15. Nice T, Pasara S, Goldfarb M, Doski J, Goldin A, Gow KW, Nuchtern JG, Vasudevan SA, Langer M, Beierle EA. Pediatric papillary thyroid cancer >1 cm: is total thyroidectomy necessary? J Pediatr Surg. 2015 Jun; 50(6):1009-13. PMID: 25819020.
      View in: PubMed
    16. Rojas Y, Shi YX, Zhang W, Beierle EA, Doski JJ, Goldfarb M, Goldin AB, Gow KW, Langer M, Vasudevan SA, Nuchtern JG. Primary malignant pulmonary tumors in children: a review of the national cancer data base. J Pediatr Surg. 2015 Jun; 50(6):1004-8. PMID: 25812444.
      View in: PubMed
    17. Zhang H, Dou J, Yu Y, Zhao Y, Fan Y, Cheng J, Xu X, Liu W, Guan S, Chen Z, shi Y, Patel R, Vasudevan SA, Zage PE, Zhang H, Nuchtern JG, Kim ES, Fu S, Yang J. mTOR ATP-competitive inhibitor INK128 inhibits neuroblastoma growth via blocking mTORC signaling. Apoptosis. 2015 Jan; 20(1):50-62. PMID: 25425103; PMCID: PMC4593396.
    18. Sadler C, Gow KW, Beierle EA, Doski JJ, Langer M, Nuchtern JG, Vasudevan SA, Goldfarb M. Parathyroid carcinoma in more than 1,000 patients: A population-level analysis. Surgery. 2014 Dec; 156(6):1622-9; discussion 1629-30. PMID: 25456964.
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    19. Mazloom A, Louis CU, Nuchtern J, Kim E, Russell H, Allen-Rhoades W, Krance R, Paulino AC. Radiation therapy to the primary and postinduction chemotherapy MIBG-avid sites in high-risk neuroblastoma. Int J Radiat Oncol Biol Phys. 2014 Nov 15; 90(4):858-62. PMID: 25245583.
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    20. Ma IT, Rojas Y, Masand PM, Castro EC, Himes RW, Kim ES, Goss JA, Nuchtern JG, Finegold MJ, Thompson PA, Vasudevan SA. Focal nodular hyperplasia in children: an institutional experience with review of the literature. J Pediatr Surg. 2015 Mar; 50(3):382-7. PMID: 25746693.
      View in: PubMed
    21. Rojas Y, Guillerman RP, Zhang W, Vasudevan SA, Nuchtern JG, Thompson PA. Relapse surveillance in AFP-positive hepatoblastoma: re-evaluating the role of imaging. Pediatr Radiol. 2014 Oct; 44(10):1275-80. PMID: 24839140.
      View in: PubMed
    22. Fallon SC, Kim ME, Fernandes CJ, Vasudevan SA, Nuchtern JG, Kim ES. Identifying and reducing early complications of surgical central lines in infants and toddlers. J Surg Res. 2014 Jul; 190(1):246-50. PMID: 24811915.
      View in: PubMed
    23. Cheng J, Fan YH, Xu X, Zhang H, Dou J, Tang Y, Zhong X, Rojas Y, Yu Y, Zhao Y, Vasudevan SA, Zhang H, Nuchtern JG, Kim ES, Chen X, Lu F, Yang J. A small-molecule inhibitor of UBE2N induces neuroblastoma cell death via activation of p53 and JNK pathways. Cell Death Dis. 2014; 5:e1079. PMID: 24556694; PMCID: PMC3944268.
    24. Fan YH, Cheng J, Vasudevan SA, Dou J, Zhang H, Patel RH, Ma IT, Rojas Y, Zhao Y, Yu Y, Zhang H, Shohet JM, Nuchtern JG, Kim ES, Yang J. USP7 inhibitor P22077 inhibits neuroblastoma growth via inducing p53-mediated apoptosis. Cell Death Dis. 2013; 4:e867. PMID: 24136231; PMCID: PMC3920959.
    25. Fan Y, Cheng J, Vasudevan SA, Patel RH, Liang L, Xu X, Zhao Y, Jia W, Lu F, Zhang H, Nuchtern JG, Kim ES, Yang J. TAK1 inhibitor 5Z-7-oxozeaenol sensitizes neuroblastoma to chemotherapy. Apoptosis. 2013 Oct; 18(10):1224-34. PMID: 23700229; PMCID: PMC3778057.
    26. Liu Y, Seipel C, Lopez ME, Nuchtern JG, Brandt ML, Fallon SC, Manyang PA, Tjia IM, Baijal RG, Watcha MF. A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children. Paediatr Anaesth. 2013 Dec; 23(12):1187-92. PMID: 24112856.
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    27. Rojas Y, Slater BJ, Braverman RM, Eldin KW, Thompson PA, Wesson DE, Nuchtern JG. Extrarenal Wilms tumor: a case report and review of the literature. J Pediatr Surg. 2013 Jun; 48(6):E33-5. PMID: 23845655.
      View in: PubMed
    28. Fallon SC, Larimer EL, Gwilliam NR, Nuchtern JG, Rodriguez JR, Lee TC, Lopez ME, Kim ES. Increased complication rates associated with Port-a-Cath placement in pediatric patients: location matters. J Pediatr Surg. 2013 Jun; 48(6):1263-8. PMID: 23845616.
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    29. Fallon SC, Coker MT, Hernandez JA, Pimpalwar SA, Minifee PK, Fishman DS, Nuchtern JG, Naik-Mathuria BJ. Traumatic hepatic artery laceration managed by transarterial embolization in a pediatric patient. J Pediatr Surg. 2013 May; 48(5):E9-12. PMID: 23701809.
      View in: PubMed
    30. Wangler MF, Chavan R, Hicks MJ, Nuchtern JG, Hegde M, Plon SE, Thompson PA. Unusually early presentation of small-bowel adenocarcinoma in a patient with Peutz-Jeghers syndrome. J Pediatr Hematol Oncol. 2013 May; 35(4):323-8. PMID: 23426006; PMCID: PMC3708690.
    31. Fallon SC, Slater BJ, Nuchtern JG, Cass DL, Kim ES, Lopez ME, Mazziotti MV. Complications related to the Nuss procedure: minimizing risk with operative technique. J Pediatr Surg. 2013 May; 48(5):1044-8. PMID: 23701780.
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    32. Fallon SC, Kim ES, Naik-Mathuria BJ, Nuchtern JG, Cassady CI, Rodriguez JR. Needle decompression to avoid tension pneumoperitoneum and hemodynamic compromise after pneumatic reduction of pediatric intussusception. Pediatr Radiol. 2013 Jun; 43(6):662-7. PMID: 23283408.
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    33. Rojas Y, Warneke CL, Dhamne CA, Tsao K, Nuchtern JG, Lally KP, Vasudevan SA, Hayes-Jordan AA, Cass DL, Herzog CE, Hicks MJ, Kim ES, Austin MT. Primary malignant pancreatic neoplasms in children and adolescents: a 20 year experience. J Pediatr Surg. 2012 Dec; 47(12):2199-204. PMID: 23217876.
      View in: PubMed
    34. Nuchtern JG, London WB, Barnewolt CE, Naranjo A, McGrady PW, Geiger JD, Diller L, Schmidt ML, Maris JM, Cohn SL, Shamberger RC. A prospective study of expectant observation as primary therapy for neuroblastoma in young infants: a Children's Oncology Group study. Ann Surg. 2012 Oct; 256(4):573-80. PMID: 22964741.
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    35. Gwilliam NR, Lazar DA, Brandt ML, Mahoney DH, Wesson DE, Mazziotti MV, Nuchtern JG, Lee TC. An analysis of outcomes and treatment costs for children undergoing splenectomy for chronic immune thrombocytopenia purpura. J Pediatr Surg. 2012 Aug; 47(8):1537-41. PMID: 22901913.
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    36. Hassan SF, Mathur S, Magliaro TJ, Larimer EL, Ferrell LB, Vasudevan SA, Patterson DM, Louis CU, Russell HV, Nuchtern JG, Kim ES. Needle core vs open biopsy for diagnosis of intermediate- and high-risk neuroblastoma in children. J Pediatr Surg. 2012 Jun; 47(6):1261-6. PMID: 22703803.
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    37. Chavan RS, Patel KU, Roy A, Thompson PA, Chintagumpala M, Goss JA, Nuchtern JG, Finegold MJ, Parsons DW, López-Terrada DH. Mutations of PTCH1, MLL2, and MLL3 are not frequent events in hepatoblastoma. Pediatr Blood Cancer. 2012 Jun; 58(6):1006-7. PMID: 22183980.
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    38. Muscal JA, Sun Y, Nuchtern JG, Dauser RC, McGuffey LH, Gibson BW, Berg SL. Plasma and cerebrospinal fluid pharmacokinetics of thalidomide and lenalidomide in nonhuman primates. Cancer Chemother Pharmacol. 2012 Apr; 69(4):943-7. PMID: 22109830; PMCID: PMC3685292.
    39. Shang X, Vasudevan SA, Yu Y, Ge N, Ludwig AD, Wesson CL, Wang K, Burlingame SM, Zhao YJ, Rao PH, Lu X, Russell HV, Okcu MF, Hicks MJ, Shohet JM, Donehower LA, Nuchtern JG, Yang J. Dual-specificity phosphatase 26 is a novel p53 phosphatase and inhibits p53 tumor suppressor functions in human neuroblastoma. Oncogene. 2010 Sep 2; 29(35):4938-46. PMID: 20562916.
      View in: PubMed
    40. Baxter PA, Thompson PA, McGuffey LM, Gibson BW, Dauser RC, Nuchtern JG, Shi C, Inloes R, Choy G, Redkar S, Blaney SM. Plasma and cerebrospinal fluid pharmacokinetics of MP470 in non-human primates. Cancer Chemother Pharmacol. 2011 Apr; 67(4):809-12. PMID: 20563581.
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    41. Kitagawa RS, Satyan KB, Relyea K, Dauser RC, Nuchtern JG, Minifee PK, Whitehead WE, Curry DJ, Luerssen TG, Jea A. Video-assisted thorascopic repair of a subarachnoid-pleural fistula in a child after thoracic tumor resection: technical note. Spine (Phila Pa 1976). 2010 Apr 20; 35(9):E347-50. PMID: 20375768.
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    42. Vasudevan SA, Shang X, Shang X, Chang S, Ge N, Diaz-Miron JL, Russell HV, Hicks MJ, Ludwig AD, Wesson CL, Burlingame SM, Kim ES, Khan J, Yang J, Nuchtern JG. Neuroblastoma-derived secretory protein is a novel secreted factor overexpressed in neuroblastoma. Mol Cancer Ther. 2009 Aug; 8(8):2478-89. PMID: 19671756; PMCID: PMC3618953.
    43. Shang X, Burlingame SM, Okcu MF, Ge N, Russell HV, Egler RA, David RD, Vasudevan SA, Yang J, Nuchtern JG. Aurora A is a negative prognostic factor and a new therapeutic target in human neuroblastoma. Mol Cancer Ther. 2009 Aug; 8(8):2461-9. PMID: 19671766; PMCID: PMC3966113.
    44. Muscal JA, Thompson PA, Giranda VL, Dayton BD, Bauch J, Horton T, McGuffey L, Nuchtern JG, Dauser RC, Gibson BW, Blaney SM, Su JM. Plasma and cerebrospinal fluid pharmacokinetics of ABT-888 after oral administration in non-human primates. Cancer Chemother Pharmacol. 2010 Feb; 65(3):419-25. PMID: 19526240; PMCID: PMC2953793.
    45. Baxter PA, Nuchtern JG, Guillerman RP, Mahoney DH, Teruya J, Chintagumpala M, Yee DL. Acquired von Willebrand syndrome and Wilms tumor: not always benign. Pediatr Blood Cancer. 2009 Mar; 52(3):392-4. PMID: 19006222.
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    46. Monclair T, Brodeur GM, Ambros PF, Brisse HJ, Cecchetto G, Holmes K, Kaneko M, London WB, Matthay KK, Nuchtern JG, von Schweinitz D, Simon T, Cohn SL, Pearson AD. The International Neuroblastoma Risk Group (INRG) staging system: an INRG Task Force report. J Clin Oncol. 2009 Jan 10; 27(2):298-303. PMID: 19047290; PMCID: PMC2650389.
    47. Kilburn LB, Bonate PL, Blaney SM, McGuffey L, Nuchtern JG, Dauser R, Thompson P, Gibson BW, Berg SL. Plasma and cerebrospinal fluid pharmacokinetics of tasidotin (ILX-651) and its metabolites in non-human primates. Cancer Chemother Pharmacol. 2009 Jul; 64(2):335-40. PMID: 19043710.
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    48. Egler RA, Burlingame SM, Nuchtern JG, Russell HV. Interleukin-6 and soluble interleukin-6 receptor levels as markers of disease extent and prognosis in neuroblastoma. Clin Cancer Res. 2008 Nov 1; 14(21):7028-34. PMID: 18980999; PMCID: PMC2613275.
    49. Plon SE, Pirics ML, Nuchtern J, Hicks J, Russell H, Agrawal S, Zbuk K, Eng C, Hegde M, Chin EL. Multiple tumors in a child with germ-line mutations in TP53 and PTEN. N Engl J Med. 2008 Jul 31; 359(5):537-9. PMID: 18669439.
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    50. Yu Y, Ge N, Xie M, Sun W, Burlingame S, Pass AK, Nuchtern JG, Zhang D, Fu S, Schneider MD, Fan J, Yang J. Phosphorylation of Thr-178 and Thr-184 in the TAK1 T-loop is required for interleukin (IL)-1-mediated optimal NFkappaB and AP-1 activation as well as IL-6 gene expression. J Biol Chem. 2008 Sep 5; 283(36):24497-505. PMID: 18617512; PMCID: PMC2528992.
    51. Lazar D, Naik B, Fitch ME, Nuchtern JG, Brandt ML. Transumbilical pyloromyotomy with umbilicoplasty provides ease of access and excellent cosmetic results. J Pediatr Surg. 2008 Jul; 43(7):1408-10. PMID: 18639709.
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    52. Miniati D, Gay AN, Parks KV, Naik-Mathuria BJ, Hicks J, Nuchtern JG, Cass DL, Olutoye OO. Imaging accuracy and incidence of Wilms' and non-Wilms' renal tumors in children. J Pediatr Surg. 2008 Jul; 43(7):1301-7. PMID: 18639686.
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    53. McLoughlin GS, Nuchtern JG, Dauser RC, Sciubba DM, Gokaslan ZL, Wolinsky JP. Mediastinal lymphangioma presenting as an acute epidural hematoma. J Neurosurg Pediatr. 2008 Jun; 1(6):474-6. PMID: 18518699.
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    54. Vasudevan SA, Russell HV, Okcu MF, Burlingame SM, Liu ZJ, Yang J, Nuchtern JG. Neuroblastoma-derived secretory protein messenger RNA levels correlate with high-risk neuroblastoma. J Pediatr Surg. 2007 Jan; 42(1):148-52. PMID: 17208556.
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    55. Berg SL, Brueckner C, Nuchtern JG, Dauser R, McGuffey L, Blaney SM. Plasma and cerebrospinal fluid pharmacokinetics of nelarabine in nonhuman primates. Cancer Chemother Pharmacol. 2007 May; 59(6):743-7. PMID: 16953392.
      View in: PubMed
    56. Stapleton SL, Reid JM, Thompson PA, Ames MM, McGovern RM, McGuffey L, Nuchtern J, Dauser R, Blaney SM. Plasma and cerebrospinal fluid pharmacokinetics of pemetrexed after intravenous administration in non-human primates. Cancer Chemother Pharmacol. 2007 Mar; 59(4):461-6. PMID: 16855840.
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    57. Vasudevan SA, Patel JC, Wesson DE, Plon SE, Finegold MJ, Nuchtern JG. Severe dysplasia in children with familial adenomatous polyposis: rare or simply overlooked? J Pediatr Surg. 2006 Apr; 41(4):658-61. PMID: 16567172.
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    58. Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM. Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene. 2006 Jul 6; 25(29):4027-32. PMID: 16518415.
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    59. Nuchtern JG. Perinatal neuroblastoma. Semin Pediatr Surg. 2006 Feb; 15(1):10-6. PMID: 16458841.
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    60. Vasudevan SA, Cumbie TA, Dishop MK, Nuchtern JG. Retroperitoneal hemangioma of infancy. J Pediatr Surg. 2006 Jan; 41(1):e41-4. PMID: 16410088.
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    61. Miniati DN, Chintagumpala M, Langston C, Dishop MK, Olutoye OO, Nuchtern JG, Cass DL. Prenatal presentation and outcome of children with pleuropulmonary blastoma. J Pediatr Surg. 2006 Jan; 41(1):66-71. PMID: 16410110.
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    62. Russell HV, Golding LA, Suell MN, Nuchtern JG, Strother DR. The role of bone marrow evaluation in the staging of patients with otherwise localized, low-risk neuroblastoma. Pediatr Blood Cancer. 2005 Dec; 45(7):916-9. PMID: 16078212.
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    63. Berg SL, Bonate PL, Nuchtern JG, Dauser R, McGuffey L, Bernacky B, Blaney SM. Plasma and cerebrospinal fluid pharmacokinetics of clofarabine in nonhuman primates. Clin Cancer Res. 2005 Aug 15; 11(16):5981-3. PMID: 16115942.
      View in: PubMed
    64. Vasudevan SA, Skoko J, Wang K, Burlingame SM, Patel PN, Lazo JS, Nuchtern JG, Yang J. MKP-8, a novel MAPK phosphatase that inhibits p38 kinase. Biochem Biophys Res Commun. 2005 May 6; 330(2):511-8. PMID: 15796912.
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    65. Edwards MJ, Kollenberg SJ, Brandt ML, Wesson DE, Nuchtern JG, Minifee PK, Cass DL. Surgery for peptic ulcer disease in children in the post-histamine2-blocker era. J Pediatr Surg. 2005 May; 40(5):850-4. PMID: 15937829.
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    66. Vasudevan SA, Nuchtern JG, Shohet JM. Gene profiling of high risk neuroblastoma. World J Surg. 2005 Mar; 29(3):317-24. PMID: 15706435.
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    67. Russell HV, Hicks J, Okcu MF, Nuchtern JG. CXCR4 expression in neuroblastoma primary tumors is associated with clinical presentation of bone and bone marrow metastases. J Pediatr Surg. 2004 Oct; 39(10):1506-11. PMID: 15486895.
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    68. Zhang L, Plon SE, Nuchtern JG, Burlingame S, Blaney S, Rousseau R, Berg S. Cyclin D and cisplatin cytotoxicity in primary neuroblastoma cell lines. Anticancer Drugs. 2004 Oct; 15(9):883-8. PMID: 15457129.
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    69. Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14228-33. PMID: 15381773; PMCID: PMC521140.
    70. Berg SL, Aleksic A, McGuffey L, Dauser R, Nuchtern J, Bernacky B, Blaney SM. Plasma and cerebrospinal fluid pharmacokinetics of rebeccamycin (NSC 655649) in nonhuman primates. Cancer Chemother Pharmacol. 2004 Aug; 54(2):127-30. PMID: 15150671.
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    71. Glick RD, Hicks MJ, Nuchtern JG, Wesson DE, Olutoye OO, Cass DL. Renal tumors in infants less than 6 months of age. J Pediatr Surg. 2004 Apr; 39(4):522-5. PMID: 15065020.
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    72. Berg SL, Stone J, Xiao JJ, Chan KK, Nuchtern J, Dauser R, McGuffey L, Thompson P, Blaney SM. Plasma and cerebrospinal fluid pharmacokinetics of depsipeptide (FR901228) in nonhuman primates. Cancer Chemother Pharmacol. 2004 Jul; 54(1):85-8. PMID: 15042312.
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    73. Thompson PA, Berg SL, Aleksic A, Kerr JZ, McGuffey L, Dauser R, Nuchtern JG, Hausheer F, Blaney SM. Plasma and cerebrospinal fluid pharmacokinetic study of BNP1350 in nonhuman primates. Cancer Chemother Pharmacol. 2004 Jun; 53(6):527-32. PMID: 14997342.
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    74. Sheth RD, Brandt ML, Brewer ED, Nuchtern JG, Kale AS, Goldstein SL. Permanent hemodialysis vascular access survival in children and adolescents with end-stage renal disease. Kidney Int. 2002 Nov; 62(5):1864-9. PMID: 12371990.
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    75. Rossig C, Bollard CM, Nuchtern JG, Rooney CM, Brenner MK. Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy. Blood. 2002 Mar 15; 99(6):2009-16. PMID: 11877273.
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    76. Shohet JM, Hicks MJ, Plon SE, Burlingame SM, Stuart S, Chen SY, Brenner MK, Nuchtern JG. Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma. Cancer Res. 2002 Feb 15; 62(4):1123-8. PMID: 11861392.
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    77. Rossig C, Bollard CM, Nuchtern JG, Merchant DA, Brenner MK. Targeting of G(D2)-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes. Int J Cancer. 2001 Oct 15; 94(2):228-36. PMID: 11668503.
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    78. Sheth RD, Kale AS, Brewer ED, Brandt ML, Nuchtern JG, Goldstein SL. Successful use of Tesio catheters in pediatric patients receiving chronic hemodialysis. Am J Kidney Dis. 2001 Sep; 38(3):553-9. PMID: 11532688.
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    79. Sarkar AK, Burlingame SM, Zang YQ, Dulai V, Hicks MJ, Strother DR, Nuchtern JG. Major histocompatibility complex-restricted lysis of neuroblastoma cells by autologous cytotoxic T lymphocytes. J Immunother. 2001 Jul-Aug; 24(4):305-11. PMID: 11565832.
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    80. Cass DL, Hawkins E, Brandt ML, Chintagumpala M, Bloss RS, Milewicz AL, Minifee PK, Wesson DE, Nuchtern JG. Surgery for ovarian masses in infants, children, and adolescents: 102 consecutive patients treated in a 15-year period. J Pediatr Surg. 2001 May; 36(5):693-9. PMID: 11329568.
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    81. Kerr JZ, Berg SL, Dauser R, Nuchtern J, Egorin MJ, McGuffey L, Aleksic A, Blaney S. Plasma and cerebrospinal fluid pharmacokinetics of gemcitabine after intravenous administration in nonhuman primates. Cancer Chemother Pharmacol. 2001 May; 47(5):411-4. PMID: 11391856.
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    82. Berg S, Serabe B, Aleksic A, Bomgaars L, McGuffey L, Dauser R, Durfee J, Nuchtern J, Blaney S. Pharmacokinetics and cerebrospinal fluid penetration of phenylacetate and phenylbutyrate in the nonhuman primate. Cancer Chemother Pharmacol. 2001 May; 47(5):385-90. PMID: 11391852.
      View in: PubMed
    83. Dilley A, Wesson D, Munden M, Hicks J, Brandt M, Minifee P, Nuchtern J. The impact of ultrasound examinations on the management of children with suspected appendicitis: a 3-year analysis. J Pediatr Surg. 2001 Feb; 36(2):303-8. PMID: 11172421.
      View in: PubMed
    84. Rossig C, Nuchtern JG, Brenner MK. Selection of human antitumor single-chain Fv antibodies from the B-cell repertoire of patients immunized against autologous neuroblastoma. Med Pediatr Oncol. 2000 Dec; 35(6):692-5. PMID: 11107148.
      View in: PubMed
    85. Cass DL, Brandt ML, Patel DL, Nuchtern JG, Minifee PK, Wesson DE. Peritoneal drainage as definitive treatment for neonates with isolated intestinal perforation. J Pediatr Surg. 2000 Nov; 35(11):1531-6. PMID: 11083416.
      View in: PubMed
    86. Nuchtern J, McGuffey L, Durfee J, Dauser R, Blaney SM. Modified procedure for implantation of subcutaneous central venous access devices in macaques (Macaca mulatta). Comp Med. 2000 Oct; 50(5):486-9. PMID: 11099129.
      View in: PubMed
    87. Brenner MK, Heslop H, Krance R, Horowitz M, Strother D, Nuchtern J, Grilley B, Martingano E, Cooper K. Phase I study of chemokine and cytokine gene-modified autologous neuroblastoma cells for treatment of relapsed/refractory neuroblastoma using an adenoviral vector. Hum Gene Ther. 2000 Jul 1; 11(10):1477-88. PMID: 10910144.
      View in: PubMed
    88. Sarkar AK, Nuchtern JG. Lysis of MYCN-amplified neuroblastoma cells by MYCN peptide-specific cytotoxic T lymphocytes. Cancer Res. 2000 Apr 1; 60(7):1908-13. PMID: 10766179.
      View in: PubMed
    89. Riva L, Blaney SM, Dauser R, Nuchtern JG, Durfee J, McGuffey L, Berg SL. Pharmacokinetics and cerebrospinal fluid penetration of CI-994 (N-acetyldinaline) in the nonhuman primate. Clin Cancer Res. 2000 Mar; 6(3):994-7. PMID: 10741726.
      View in: PubMed
    90. Carpenter RO, Schaffer RL, Maeso CE, Sasan F, Nuchtern JG, Jaksic T, Harberg FJ, Wesson DE, Brandt ML. Postoperative ad lib feeding for hypertrophic pyloric stenosis. J Pediatr Surg. 1999 Jun; 34(6):959-61. PMID: 10392913.
      View in: PubMed
    91. Kerr JZ, Hicks MJ, Nuchtern JG, Saldivar V, Heim-Hall J, Shah S, Kelly DR, Cain WS, Chintagumpala MM. Gastrointestinal autonomic nerve tumors in the pediatric population: a report of four cases and a review of the literature. Cancer. 1999 Jan 1; 85(1):220-30. PMID: 9921996.
      View in: PubMed
    92. Serabe BM, Murry DJ, Dauser R, Nuchtern J, Durfee J, McGuffey L, Berg S, Blaney SM. Plasma and CSF pharmacokinetics of ganciclovir in nonhuman primates. Cancer Chemother Pharmacol. 1999; 43(5):415-8. PMID: 10100598.
      View in: PubMed
    93. Miltenburg DM, Nuchtern JG, Jaksic T, Kozinetiz C, Brandt ML. Laparoscopic evaluation of the pediatric inguinal hernia--a meta-analysis. J Pediatr Surg. 1998 Jun; 33(6):874-9. PMID: 9660219.
      View in: PubMed
    94. Saidi AS, Friedman RA, el Said H, Nuchtern JG, Fenrich AL. Ventricular tachycardia during repair of gastroschisis. Tex Heart Inst J. 1998; 25(4):306-8. PMID: 9885109; PMCID: PMC325578.
    95. Miltenburg DM, Nuchtern JG, Jaksic T, Kozinetz CA, Brandt ML. Meta-analysis of the risk of metachronous hernia in infants and children. Am J Surg. 1997 Dec; 174(6):741-4. PMID: 9409609.
      View in: PubMed
    96. Gross E, Chen MK, Lobe TE, Nuchtern JG, Rao BN. Infradiaphragmatic extralobar pulmonary sequestration masquerading as an intra-abdominal, suprarenal mass. Pediatr Surg Int. 1997 Sep; 12(7):529-31. PMID: 9238124.
      View in: PubMed
    97. Nuchtern JG, Baxter R, Hatch EI. Nonoperative initial management versus silon chimney for treatment of giant omphalocele. J Pediatr Surg. 1995 Jun; 30(6):771-6. PMID: 7666304.
      View in: PubMed
    98. Nuchtern JG, Engrav LH, Nakamura DY, Dutcher KA, Heimbach DM, Vedder NB. Treatment of fourth-degree hand burns. J Burn Care Rehabil. 1995 Jan-Feb; 16(1):36-42. PMID: 7721907.
      View in: PubMed
    99. Nuchtern JG, Harberg FJ. Congenital lung cysts. Semin Pediatr Surg. 1994 Nov; 3(4):233-43. PMID: 7850363.
      View in: PubMed
    100. Velanovich V, Ledbetter D, McGahren E, Nuchtern J, Schaller R. Foreign bodies within a Meckel's diverticulum. Arch Surg. 1992 Jul; 127(7):864. PMID: 1524488.
      View in: PubMed
    101. Hsu VW, Yuan LC, Nuchtern JG, Lippincott-Schwartz J, Hammerling GJ, Klausner RD. A recycling pathway between the endoplasmic reticulum and the Golgi apparatus for retention of unassembled MHC class I molecules. Nature. 1991 Aug 1; 352(6334):441-4. PMID: 1861723.
      View in: PubMed
    102. Nuchtern JG, Biddison WE, Klausner RD. Class II MHC molecules can use the endogenous pathway of antigen presentation. Nature. 1990 Jan 4; 343(6253):74-6. PMID: 1967486.
      View in: PubMed
    103. Nuchtern JG, Bonifacino JS, Biddison WE, Klausner RD. Brefeldin A implicates egress from endoplasmic reticulum in class I restricted antigen presentation. Nature. 1989 May 18; 339(6221):223-6. PMID: 2785645.
      View in: PubMed
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