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PETER JAY HOTEZ

TitleDean
InstitutionBaylor College of Medicine
DepartmentNational School of Tropical Medicine
AddressOne Baylor Plaza
Houston TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pediatrics
    DivisionPediatrics-Tropical Medicine

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Virology & Microbiology
    DivisionMolecular Virology & Microbiology


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Brelsford JB, Plieskatt JL, Yakovleva A, Jariwala A, Keegan BP, Peng J, Xia P, Li G, Campbell D, Periago MV, Correa-Oliveira R, Bottazzi ME, Hotez PJ, Diemert D, Bethony JM. Advances in neglected tropical disease vaccines: Developing relative potency and functional assays for the Na-GST-1/Alhydrogel hookworm vaccine. PLoS Negl Trop Dis. 2017 Feb 13; 11(2):e0005385. PMID: 28192438.
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    2. Pollet J, Versteeg L, Rezende W, Strych U, Gusovsky F, Hotez PJ, Bottazzi ME. A simple fluorescence-based assay for quantification of the Toll-Like Receptor agonist E6020 in vaccine formulations. Vaccine. 2017 Feb 09. PMID: 28190745.
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    3. Hotez PJ. Can the SDGs and GHSA achieve synergy? J Public Health Policy. 2017 Feb 07. PMID: 28174426.
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    4. Eppes C, Rac M, Dunn J, Versalovic J, Murray KO, Suter MA, Sanz Cortes M, Espinoza J, Seferovic MD, Lee W, Hotez P, Mastrobattista J, Clark SL, Belfort MA, Aagaard KM. Testing for Zika Virus (ZIKV) Infection in Pregnancy: Key Concepts to Deal with an Emerging Epidemic. Am J Obstet Gynecol. 2017 Jan 23. PMID: 28126366.
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    5. Hotez PJ, Damania A, Naghavi M. Paying for Worms. PLoS Negl Trop Dis. 2016 Dec; 10(12):e0005092. PMID: 28033369.
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    6. Loukas A, Hotez PJ, Diemert D, Yazdanbakhsh M, McCarthy JS, Correa-Oliveira R, Croese J, Bethony JM. Hookworm infection. Nat Rev Dis Primers. 2016 12 08; 2:16088. PMID: 27929101.
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    7. Hotez PJ, Kassem M. Egypt: Its Artists, Intellectuals, and Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Dec; 10(12):e0005072. PMID: 27906985.
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    8. Lo NC, Addiss DG, Hotez PJ, King CH, Stothard JR, Evans DS, Colley DG, Lin W, Coulibaly JT, Bustinduy AL, Raso G, Bendavid E, Bogoch II, Fenwick A, Savioli L, Molyneux D, Utzinger J, Andrews JR. A call to strengthen the global strategy against schistosomiasis and soil-transmitted helminthiasis: the time is now. Lancet Infect Dis. 2016 Nov 30. PMID: 27914852.
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    9. Hotez PJ. Zika Virus Is More Like Rubella Than Human Immunodeficiency Virus-Reply. JAMA Pediatr. 2016 Nov 01; 170(11):1116. PMID: 27617894.
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    10. Hotez PJ, Damania A, Naghavi M. Blue Marble Health and the Global Burden of Disease Study 2013. PLoS Negl Trop Dis. 2016 Oct; 10(10):e0004744. PMID: 27788134.
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    11. Navarro S, Pickering DA, Ferreira IB, Jones L, Ryan S, Troy S, Leech A, Hotez PJ, Zhan B, Laha T, Prentice R, Sparwasser T, Croese J, Engwerda CR, Upham JW, Julia V, Giacomin PR, Loukas A. Hookworm recombinant protein promotes regulatory T cell responses that suppress experimental asthma. Sci Transl Med. 2016 Oct 26; 8(362):362ra143. PMID: 27797959.
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    12. Hotez PJ. Texas and Its Measles Epidemics. PLoS Med. 2016 Oct; 13(10):e1002153. PMID: 27780206.
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    13. McAtee CP, Seid CA, Hammond M, Hudspeth E, Keegan BP, Liu Z, Wei J, Zhan B, Arjona-Sabido R, Cruz-Chan V, Dumonteil E, Hotez PJ, Bottazzi ME. Expression, purification, immunogenicity and protective efficacy of a recombinant nucleoside hydrolase from Leishmania donovani, a vaccine candidate for preventing cutaneous leishmaniasis. Protein Expr Purif. 2017 Feb; 130:129-136. PMID: 27773761.
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    14. Seid CA, Jones KM, Pollet J, Keegan B, Hudspeth E, Hammond M, Wei J, McAtee CP, Versteeg L, Gutierrez A, Liu Z, Zhan B, Respress JL, Strych U, Bottazzi ME, Hotez PJ. Cysteine Mutagenesis Improves the Production without Abrogating Antigenicity of a Recombinant Protein Vaccine Candidate for Human Chagas Disease. Hum Vaccin Immunother. 2016 Oct 13; 0. PMID: 27737611.
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    15. Jaffer A, Hotez PJ. Somalia: A Nation at the Crossroads of Extreme Poverty, Conflict, and Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Sep; 10(9):e0004670. PMID: 27685261.
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    16. Briggs N, Weatherhead J, Sastry KJ, Hotez PJ. The Hygiene Hypothesis and Its Inconvenient Truths about Helminth Infections. PLoS Negl Trop Dis. 2016 Sep; 10(9):e0004944. PMID: 27632204.
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    17. Bartsch SM, Hotez PJ, Asti L, Zapf KM, Bottazzi ME, Diemert DJ, Lee BY. The Global Economic and Health Burden of Human Hookworm Infection. PLoS Negl Trop Dis. 2016 Sep; 10(9):e0004922. PMID: 27607360.
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    18. Mehta P, Hotez PJ. NTD and NCD Co-morbidities: The Example of Dengue Fever. PLoS Negl Trop Dis. 2016 Aug; 10(8):e0004619. PMID: 27561091.
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    19. Al-Salem W, Herricks JR, Hotez PJ. A review of visceral leishmaniasis during the conflict in South Sudan and the consequences for East African countries. Parasit Vectors. 2016; 9:460. PMID: 27549162; PMCID: PMC4994383.
    20. Hotez PJ. The World's Great Religions and Their Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Jul; 10(7):e0004544. PMID: 27467213; PMCID: PMC4965142.
    21. Hess JA, Zhan B, Torigian AR, Patton JB, Petrovsky N, Zhan T, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice. PLoS Negl Trop Dis. 2016 Jul; 10(7):e0004797. PMID: 27387453; PMCID: PMC4936747.
    22. Hotez PJ. Southern Europe's Coming Plagues: Vector-Borne Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Jun; 10(6):e0004243. PMID: 27362640.
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    23. Hotez PJ. What Does Zika Virus Mean for the Children of the Americas? JAMA Pediatr. 2016 Jun 20. PMID: 27322491.
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    24. Hotez PJ. Will Zika return to the 'Old World'? Microbes Infect. 2016 May 27. PMID: 27242327.
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    25. Du R, Hotez PJ, Al-Salem WS, Acosta-Serrano A. Old World Cutaneous Leishmaniasis and Refugee Crises in the Middle East and North Africa. PLoS Negl Trop Dis. 2016 May; 10(5):e0004545. PMID: 27227772; PMCID: PMC4882064.
    26. Hotez PJ. Zika in the United States of America and a Fateful 1969 Decision. PLoS Negl Trop Dis. 2016 May; 10(5):e0004765. PMID: 27227971; PMCID: PMC4882008.
    27. Kim H, Marks F, Novakovic U, Hotez PJ, Black RE. Multi-stakeholder partnerships with the Democratic Peoples' Republic of Korea to improve childhood immunization. Trop Med Int Health. 2016 May 9. PMID: 27159122.
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    28. Hotez PJ, Strych U, Lustigman S, Bottazzi ME. Human anthelminthic vaccines: Rationale and challenges. Vaccine. 2016 May 9. PMID: 27171753.
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    29. Hotez PJ. Neglected Tropical Diseases in the Anthropocene: The Cases of Zika, Ebola, and Other Infections. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004648. PMID: 27058728; PMCID: PMC4825952.
    30. Arumugam S, Wei J, Liu Z, Abraham D, Bell A, Bottazzi ME, Hotez PJ, Zhan B, Lustigman S, Klei TR. Vaccination of Gerbils with Bm-103 and Bm-RAL-2 Concurrently or as a Fusion Protein Confers Consistent and Improved Protection against Brugia malayi Infection. PLoS Negl Trop Dis. 2016 Apr; 10(4):e0004586. PMID: 27045170; PMCID: PMC4821550.
    31. Hotez PJ. The South China Sea and Its Neglected Tropical Diseases. PLoS Negl Trop Dis. 2016 Mar; 10(3):e0004395. PMID: 27031342; PMCID: PMC4816286.
    32. Hotez PJ, Beaumier CM, Gillespie PM, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent hookworm disease and anemia. Vaccine. 2016 Mar 31. PMID: 27040400.
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    33. Merrifield M, Hotez PJ, Beaumier CM, Gillespie P, Strych U, Hayward T, Bottazzi ME. Advancing a vaccine to prevent human schistosomiasis. Vaccine. 2016 Mar 29. PMID: 27036511.
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    34. Beaumier CM, Gillespie PM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for Chagas disease. Vaccine. 2016 Mar 26. PMID: 27026146.
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    35. Bartsch SM, Hotez PJ, Hertenstein DL, Diemert DJ, Zapf KM, Bottazzi ME, Bethony JM, Brown ST, Lee BY. Modeling the economic and epidemiologic impact of hookworm vaccine and mass drug administration (MDA) in Brazil, a high transmission setting. Vaccine. 2016 Apr 27; 34(19):2197-206. PMID: 27002501.
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    36. Gillespie PM, Beaumier CM, Strych U, Hayward T, Hotez PJ, Bottazzi ME. Status of vaccine research and development of vaccines for leishmaniasis. Vaccine. 2016 Mar 11. PMID: 26973063.
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    37. Hotez PJ, Pecoul B, Rijal S, Boehme C, Aksoy S, Malecela M, Tapia-Conyer R, Reeder JC. Eliminating the Neglected Tropical Diseases: Translational Science and New Technologies. PLoS Negl Trop Dis. 2016 Mar; 10(3):e0003895. PMID: 26934395; PMCID: PMC4774924.
    38. Barry MA, Murray KO, Hotez PJ, Jones KM. Impact of vectorborne parasitic neglected tropical diseases on child health. Arch Dis Child. 2016 Feb 26. PMID: 26921274.
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    39. Pecoul B, Batista C, Stobbaerts E, Ribeiro I, Vilasanjuan R, Gascon J, Pinazo MJ, Moriana S, Gold S, Pereiro A, Navarro M, Torrico F, Bottazzi ME, Hotez PJ. The BENEFIT Trial: Where Do We Go from Here? PLoS Negl Trop Dis. 2016 Feb; 10(2):e0004343. PMID: 26913759; PMCID: PMC4767872.
    40. Barry MA, Wang Q, Jones KM, Heffernan MJ, Buhaya MH, Beaumier CM, Keegan BP, Zhan B, Dumonteil E, Bottazzi ME, Hotez PJ. A therapeutic nanoparticle vaccine against Trypanosoma cruzi in a BALB/c mouse model of Chagas disease. Hum Vaccin Immunother. 2016 Apr 2; 12(4):976-87. PMID: 26890466.
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    41. Hudspeth EM, Wang Q, Seid CA, Hammond M, Wei J, Liu Z, Zhan B, Pollet J, Heffernan MJ, McAtee CP, Engler DA, Matsunami RK, Strych U, Asojo OA, Hotez PJ, Bottazzi ME. Expression and purification of an engineered, yeast-expressed Leishmania donovani nucleoside hydrolase with immunogenic properties. Hum Vaccin Immunother. 2016 Feb 2; 1-14. PMID: 26839079.
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    42. Garcia MN, Hernandez D, Gorchakov R, Murray KO, Hotez PJ. The 1899 United States Kissing Bug Epidemic. PLoS Negl Trop Dis. 2015 Dec; 9(12):e0004117. PMID: 26719888.
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    43. Hotez PJ, Herricks JR. Impact of the Neglected Tropical Diseases on Human Development in the Organisation of Islamic Cooperation Nations. PLoS Negl Trop Dis. 2015 Nov; 9(11):e0003782. PMID: 26606509.
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    44. Gunter SM, Jones KM, Zhan B, Essigmann HT, Murray KO, Garcia MN, Gorchakov R, Bottazzi ME, Hotez PJ, Brown EL. Identification and Characterization of the Trypanosoma cruzi B-cell Superantigen Tc24. Am J Trop Med Hyg. 2016 Jan 6; 94(1):114-21. PMID: 26598565.
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    45. Garcia MN, Woc-Colburn L, Aguilar D, Hotez PJ, Murray KO. Historical Perspectives on the Epidemiology of Human Chagas Disease in Texas and Recommendations for Enhanced Understanding of Clinical Chagas Disease in the Southern United States. PLoS Negl Trop Dis. 2015 Nov; 9(11):e0003981. PMID: 26540273.
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    46. Zhan B, Ajmera R, Geiger SM, Gonçalves MT, Liu Z, Wei J, Wilkins PP, Fujiwara R, Gazzinelli-Guimaraes PH, Bottazzi ME, Hotez P. Identification of immunodominant antigens for the laboratory diagnosis of toxocariasis. Trop Med Int Health. 2015 Dec; 20(12):1787-96. PMID: 26426162.
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    47. Anderson JP, Rascoe LN, Levert K, Chastain HM, Reed MS, Rivera HN, McAuliffe I, Zhan B, Wiegand RE, Hotez PJ, Wilkins PP, Pohl J, Handali S. Development of a Luminex Bead Based Assay for Diagnosis of Toxocariasis Using Recombinant Antigens Tc-CTL-1 and Tc-TES-26. PLoS Negl Trop Dis. 2015 Oct; 9(10):e0004168. PMID: 26485145.
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    48. Hotez PJ, Bottazzi ME, Strych U. New Vaccines for the World's Poorest People. Annu Rev Med. 2016 Jan 14; 67:405-17. PMID: 26356803.
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    49. Murray KO, Fischer RS, Chavarria D, Duttmann C, Garcia MN, Gorchakov R, Hotez PJ, Jiron W, Leibler JH, Lopez JE, Mandayam S, Marin A, Sheleby J. Mesoamerican nephropathy: a neglected tropical disease with an infectious etiology? Microbes Infect. 2015 Oct; 17(10):671-5. PMID: 26320026.
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    50. Weatherhead JE, Hotez PJ. Worm Infections in Children. Pediatr Rev. 2015 Aug; 36(8):341-52; quiz 353-4. PMID: 26232464.
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    51. Martinez-Campos V, Martinez-Vega P, Ramirez-Sierra MJ, Rosado-Vallado M, Seid CA, Hudspeth EM, Wei J, Liu Z, Kwityn C, Hammond M, Ortega-López J, Zhan B, Hotez PJ, Bottazzi ME, Dumonteil E. Expression, purification, immunogenicity, and protective efficacy of a recombinant Tc24 antigen as a vaccine against Trypanosoma cruzi infection in mice. Vaccine. 2015 Aug 26; 33(36):4505-12. PMID: 26192358.
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    52. Hotez PJ. Neglected Tropical Diseases in the Ebola-Affected Countries of West Africa. PLoS Negl Trop Dis. 2015 Jun; 9(6):e0003671. PMID: 26110778.
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    53. Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Aug 22; 386(9995):743-800. PMID: 26063472; PMCID: PMC4561509.
    54. Hotez PJ. Blue marble health and "the big three diseases": HIV/AIDS, tuberculosis, and malaria. Microbes Infect. 2015 Aug; 17(8):539-41. PMID: 26003523.
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    55. Hotez PJ. Combating the next lethal epidemic. Science. 2015 Apr 17; 348(6232):296-7. PMID: 25883348.
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    56. Hotez PJ, Bottazzi ME, Strych U, Chang LY, Lim YA, Goodenow MM, AbuBakar S. Neglected tropical diseases among the Association of Southeast Asian Nations (ASEAN): overview and update. PLoS Negl Trop Dis. 2015 Apr; 9(4):e0003575. PMID: 25880767; PMCID: PMC4400050.
    57. Li MG, Hotez PJ, Vrabec JT, Donovan DT. Is chronic suppurative otitis media a neglected tropical disease? PLoS Negl Trop Dis. 2015 Mar; 9(3):e0003485. PMID: 25811602; PMCID: PMC4374690.
    58. Hotez PJ, Bottazzi ME, Dumonteil E, Buekens P. The Gulf of Mexico: a "hot zone" for neglected tropical diseases? PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003481. PMID: 25719411; PMCID: PMC4342336.
    59. Preidis GA, Hotez PJ. The newest "omics"--metagenomics and metabolomics--enter the battle against the neglected tropical diseases. PLoS Negl Trop Dis. 2015 Feb; 9(2):e0003382. PMID: 25675250; PMCID: PMC4326130.
    60. Hotez PJ, Bottazzi ME, Zhan B, Makepeace BL, Klei TR, Abraham D, Taylor DW, Lustigman S. The Onchocerciasis Vaccine for Africa--TOVA--Initiative. PLoS Negl Trop Dis. 2015 Jan; 9(1):e0003422. PMID: 25634641; PMCID: PMC4310604.
    61. Turkeltaub JA, McCarty TR, Hotez PJ. The intestinal protozoa: emerging impact on global health and development. Curr Opin Gastroenterol. 2015 Jan; 31(1):38-44. PMID: 25394233.
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    62. Baring E, Hotez PJ. Yemen: fighting neglected tropical diseases against all odds. PLoS Negl Trop Dis. 2014 Dec; 8(12):e3292. PMID: 25521710; PMCID: PMC4270485.
    63. Jiang S, Hotez PJ. Combating the emerging viral infectious diseases. Microbes Infect. 2015 Feb; 17(2):83. PMID: 25529754.
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    64. Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet. 2015 Jan 10; 385(9963):117-71. PMID: 25530442; PMCID: PMC4340604.
    65. Hotez PJ. The medical biochemistry of poverty and neglect. Mol Med. 2014; 20 Suppl 1:S31-6. PMID: 25549231; PMCID: PMC4374519.
    66. Knight JM, Zingales B, Bottazzi ME, Hotez P, Zhan B. Limited antigenic variation in the Trypanosoma cruzi candidate vaccine antigen TSA-1. Parasite Immunol. 2014 Dec; 36(12):708-12. PMID: 25040249.
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    67. Hotez PJ. Global christianity and the control of its neglected tropical diseases. PLoS Negl Trop Dis. 2014 Nov; 8(11):e3135. PMID: 25412254; PMCID: PMC4238975.
    68. Garcia MN, Aguilar D, Gorchakov R, Rossmann SN, Montgomery SP, Rivera H, Woc-Colburn L, Hotez PJ, Murray KO. Evidence of autochthonous Chagas disease in southeastern Texas. Am J Trop Med Hyg. 2015 Feb; 92(2):325-30. PMID: 25371187; PMCID: PMC4347336.
    69. Ndeffo Mbah ML, Skrip L, Greenhalgh S, Hotez P, Galvani AP. Impact of Schistosoma mansoni on malaria transmission in Sub-Saharan Africa. PLoS Negl Trop Dis. 2014 Oct; 8(10):e3234. PMID: 25329403; PMCID: PMC4199517.
    70. Garcia MN, Murray KO, Hotez PJ, Rossmann SN, Gorchakov R, Ontiveros A, Woc-Colburn L, Bottazzi ME, Rhodes CE, Ballantyne CM, Aguilar D. Development of chagas cardiac manifestations among Texas blood donors. Am J Cardiol. 2015 Jan 1; 115(1):113-7. PMID: 25456877.
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    71. Hotez PJ. Neglected infections of poverty in the United States and their effects on the brain. JAMA Psychiatry. 2014 Oct; 71(10):1099-100. PMID: 25103827.
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    72. Hotez PJ. The NTDs and vaccine diplomacy in latin America: opportunities for united states foreign policy. PLoS Negl Trop Dis. 2014 Sep; 8(9):e2922. PMID: 25255437; PMCID: PMC4177742.
    73. Hotez PJ. Neglected parasitic infections and poverty in the United States. PLoS Negl Trop Dis. 2014 Sep; 8(9):e3012. PMID: 25188455; PMCID: PMC4154650.
    74. Garcia MN, Woc-Colburn L, Rossmann SN, Townsend RL, Stramer SL, Bravo M, Kamel H, Beddard R, Townsend M, Oldham R, Bottazzi ME, Hotez PJ, Murray KO. Trypanosoma cruzi screening in Texas blood donors, 2008-2012. Epidemiol Infect. 2016 Apr; 144(5):1010-3. PMID: 25170765.
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    75. Lee RM, Moore LB, Bottazzi ME, Hotez PJ. Toxocariasis in North America: a systematic review. PLoS Negl Trop Dis. 2014 Aug; 8(8):e3116. PMID: 25166906; PMCID: PMC4148222.
    76. Rajagopal S, Hotez PJ, Bundy DA. Micronutrient supplementation and deworming in children with geohelminth infections. PLoS Negl Trop Dis. 2014 Aug; 8(8):e2920. PMID: 25101963; PMCID: PMC4125305.
    77. Hotez PJ, Fujiwara RT. Brazil's neglected tropical diseases: an overview and a report card. Microbes Infect. 2014 Aug; 16(8):601-6. PMID: 25088506.
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    78. Hotez PJ, Peiperl L. Blue marble health: a call for papers. PLoS Med. 2014 Jul; 11(7):e1001682. PMID: 25072140; PMCID: PMC4114447.
    79. Hotez PJ, Alvarado M, Basáñez MG, Bolliger I, Bourne R, Boussinesq M, Brooker SJ, Brown AS, Buckle G, Budke CM, Carabin H, Coffeng LE, Fèvre EM, Fürst T, Halasa YA, Jasrasaria R, Johns NE, Keiser J, King CH, Lozano R, Murdoch ME, O'Hanlon S, Pion SD, Pullan RL, Ramaiah KD, Roberts T, Shepard DS, Smith JL, Stolk WA, Undurraga EA, Utzinger J, Wang M, Murray CJ, Naghavi M. The global burden of disease study 2010: interpretation and implications for the neglected tropical diseases. PLoS Negl Trop Dis. 2014 Jul; 8(7):e2865. PMID: 25058013; PMCID: PMC4109880.
    80. Garcia MN, Hotez PJ, Murray KO. Potential novel risk factors for autochthonous and sylvatic transmission of human Chagas disease in the United States. Parasit Vectors. 2014; 7:311. PMID: 24996479; PMCID: PMC4094476.
    81. Hotez PJ. "Vaccine diplomacy": historical perspectives and future directions. PLoS Negl Trop Dis. 2014 Jun; 8(6):e2808. PMID: 24968231; PMCID: PMC4072536.
    82. Hotez PJ, Bottazzi ME, Tseng CT, Zhan B, Lustigman S, Du L, Jiang S. Calling for rapid development of a safe and effective MERS vaccine. Microbes Infect. 2014 Jul; 16(7):529-31. PMID: 24931059.
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    83. Hess JA, Zhan B, Bonne-Année S, Deckman JM, Bottazzi ME, Hotez PJ, Klei TR, Lustigman S, Abraham D. Vaccines to combat river blindness: expression, selection and formulation of vaccines against infection with Onchocerca volvulus in a mouse model. Int J Parasitol. 2014 Aug; 44(9):637-46. PMID: 24907553; PMCID: PMC4118642.
    84. Chhabra S, Chang SC, Nguyen HM, Huq R, Tanner MR, Londono LM, Estrada R, Dhawan V, Chauhan S, Upadhyay SK, Gindin M, Hotez PJ, Valenzuela JG, Mohanty B, Swarbrick JD, Wulff H, Iadonato SP, Gutman GA, Beeton C, Pennington MW, Norton RS, Chandy KG. Kv1.3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases. FASEB J. 2014 Sep; 28(9):3952-64. PMID: 24891519; PMCID: PMC4139903.
    85. Whitham M, Hotez P. In reply. Obstet Gynecol. 2014 Jun; 123(6):1354. PMID: 24848902.
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    86. Hotez PJ. Ten global "hotspots" for the neglected tropical diseases. PLoS Negl Trop Dis. 2014; 8(5):e2496. PMID: 24873825; PMCID: PMC4038631.
    87. Hotez PJ, Woc-Colburn L, Bottazzi ME. Neglected tropical diseases in Central America and Panama: review of their prevalence, populations at risk and impact on regional development. Int J Parasitol. 2014 Aug; 44(9):597-603. PMID: 24846528.
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    88. Hotez PJ, Murray KO, Buekens P. The Gulf Coast: a new American underbelly of tropical diseases and poverty. PLoS Negl Trop Dis. 2014 May; 8(5):e2760. PMID: 24830815; PMCID: PMC4022458.
    89. Webster JP, Molyneux DH, Hotez PJ, Fenwick A. The contribution of mass drug administration to global health: past, present and future. Philos Trans R Soc Lond B Biol Sci. 2014; 369(1645):20130434. PMID: 24821920; PMCID: PMC4024227.
    90. Parise ME, Hotez PJ, Slutsker L. Neglected parasitic infections in the United States: needs and opportunities. Am J Trop Med Hyg. 2014 May; 90(5):783-5. PMID: 24808243; PMCID: PMC4015562.
    91. Hotez PJ, Velasquez RM, Wolf JE. Neglected tropical skin diseases: their global elimination through integrated mass drug administration? JAMA Dermatol. 2014 May; 150(5):481-2. PMID: 24671756.
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    92. Hotez PJ. Could nitazoxanide be added to other essential medicines for integrated neglected tropical disease control and elimination? PLoS Negl Trop Dis. 2014 Mar; 8(3):e2758. PMID: 24675990; PMCID: PMC3967954.
    93. Tan M, Kusriastuti R, Savioli L, Hotez PJ. Indonesia: an emerging market economy beset by neglected tropical diseases (NTDs). PLoS Negl Trop Dis. 2014 Feb; 8(2):e2449. PMID: 24587452; PMCID: PMC3937254.
    94. Hotez PJ. Aboriginal populations and their neglected tropical diseases. PLoS Negl Trop Dis. 2014; 8(1):e2286. PMID: 24498442; PMCID: PMC3907312.
    95. Tang YT, Gao X, Rosa BA, Abubucker S, Hallsworth-Pepin K, Martin J, Tyagi R, Heizer E, Zhang X, Bhonagiri-Palsikar V, Minx P, Warren WC, Wang Q, Zhan B, Hotez PJ, Sternberg PW, Dougall A, Gaze ST, Mulvenna J, Sotillo J, Ranganathan S, Rabelo EM, Wilson RK, Felgner PL, Bethony J, Hawdon JM, Gasser RB, Loukas A, Mitreva M. Genome of the human hookworm Necator americanus. Nat Genet. 2014 Mar; 46(3):261-9. PMID: 24441737; PMCID: PMC3978129.
    96. Zhan B, Beaumier CM, Briggs N, Jones KM, Keegan BP, Bottazzi ME, Hotez PJ. Advancing a multivalent 'Pan-anthelmintic' vaccine against soil-transmitted nematode infections. Expert Rev Vaccines. 2014 Mar; 13(3):321-31. PMID: 24392641; PMCID: PMC3934375.
    97. McCarty TR, Turkeltaub JA, Hotez PJ. Global progress towards eliminating gastrointestinal helminth infections. Curr Opin Gastroenterol. 2014 Jan; 30(1):18-24. PMID: 24241244.
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    98. Hotez P, Whitham M. Helminth infections: a new global women's health agenda. Obstet Gynecol. 2014 Jan; 123(1):155-60. PMID: 24463676.
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    99. Curti E, Seid CA, Hudspeth E, Center L, Rezende W, Pollet J, Kwityn C, Hammond M, Matsunami RK, Engler DA, Hotez PJ, Elena Bottazzi M. Optimization and revision of the production process of the Necator americanus glutathione S-transferase 1 (Na-GST-1), the lead hookworm vaccine recombinant protein candidate. Hum Vaccin Immunother. 2014; 10(7):1914-25. PMID: 25424799; PMCID: PMC4186034.
    100. Preidis GA, Keaton MA, Campeau PM, Bessard BC, Conner ME, Hotez PJ. The undernourished neonatal mouse metabolome reveals evidence of liver and biliary dysfunction, inflammation, and oxidative stress. J Nutr. 2014 Mar; 144(3):273-81. PMID: 24381221; PMCID: PMC3927544.
    101. Chen WH, Du L, Chag SM, Ma C, Tricoche N, Tao X, Seid CA, Hudspeth EM, Lustigman S, Tseng CT, Bottazzi ME, Hotez PJ, Zhan B, Jiang S. Yeast-expressed recombinant protein of the receptor-binding domain in SARS-CoV spike protein with deglycosylated forms as a SARS vaccine candidate. Hum Vaccin Immunother. 2014; 10(3):648-58. PMID: 24355931; PMCID: PMC4130269.
    102. Beaumier CM, Gomez-Rubio AM, Hotez PJ, Weina PJ. United States military tropical medicine: extraordinary legacy, uncertain future. PLoS Negl Trop Dis. 2013; 7(12):e2448. PMID: 24386494; PMCID: PMC3873258.
    103. Keenan JD, Hotez PJ, Amza A, Stoller NE, Gaynor BD, Porco TC, Lietman TM. Elimination and eradication of neglected tropical diseases with mass drug administrations: a survey of experts. PLoS Negl Trop Dis. 2013; 7(12):e2562. PMID: 24340111; PMCID: PMC3855072.
    104. Hotez PJ. NTDs V.2.0: "blue marble health"--neglected tropical disease control and elimination in a shifting health policy landscape. PLoS Negl Trop Dis. 2013 Nov; 7(11):e2570. PMID: 24278496; PMCID: PMC3836998.
    105. Hotez PJ, Dumonteil E, Betancourt Cravioto M, Bottazzi ME, Tapia-Conyer R, Meymandi S, Karunakara U, Ribeiro I, Cohen RM, Pecoul B. An unfolding tragedy of Chagas disease in North America. PLoS Negl Trop Dis. 2013; 7(10):e2300. PMID: 24205411; PMCID: PMC3814410.
    106. Siller M, Reyes N, Hotez E, Hutman T, Sigman M. Longitudinal change in the use of services in autism spectrum disorder: understanding the role of child characteristics, family demographics, and parent cognitions. Autism. 2014 May; 18(4):433-46. PMID: 24108191.
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    107. Hotez P, Singh SK, Zhou XN. Advancing Sino-Indian cooperation to combat tropical diseases. PLoS Negl Trop Dis. 2013; 7(9):e2204. PMID: 24086775; PMCID: PMC3784467.
    108. Curti E, Kwityn C, Zhan B, Gillespie P, Brelsford J, Deumic V, Plieskatt J, Rezende WC, Tsao E, Kalampanayil B, Hotez PJ, Bottazzi ME. Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis. Hum Vaccin Immunother. 2013 Nov; 9(11):2342-50. PMID: 23899507; PMCID: PMC3981843.
    109. Rimoin AW, Hotez PJ. NTDs in the heart of darkness: the Democratic Republic of Congo's unknown burden of neglected tropical diseases. PLoS Negl Trop Dis. 2013; 7(7):e2118. PMID: 23936557; PMCID: PMC3723541.
    110. Cheng W, Curti E, Rezende WC, Kwityn C, Zhan B, Gillespie P, Plieskatt J, Joshi SB, Volkin DB, Hotez PJ, Middaugh CR, Bottazzi ME. Biophysical and formulation studies of the Schistosoma mansoni TSP-2 extracellular domain recombinant protein, a lead vaccine candidate antigen for intestinal schistosomiasis. Hum Vaccin Immunother. 2013 Nov; 9(11):2351-61. PMID: 23880663; PMCID: PMC3981844.
    111. Andrus J, Bottazzi ME, Chow J, Goraleski KA, Fisher-Hoch SP, Lambuth JK, Lee BY, Margolis HS, McCormick JB, Melby P, Murray KO, Rico-Hesse R, Valenzuela JG, Hotez PJ. Ears of the Armadillo: Global Health Research and Neglected Diseases in Texas. PLoS Negl Trop Dis. 2013 Jun; 7(6):e2021. PMID: 23826397.
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    112. Barry MA, Simon GG, Mistry N, Hotez PJ. Global trends in neglected tropical disease control and elimination: impact on child health. Arch Dis Child. 2013 Aug; 98(8):635-41. PMID: 23793132.
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    113. Hotez PJ, Diemert D, Bacon KM, Beaumier C, Bethony JM, Bottazzi ME, Brooker S, Couto AR, Freire Mda S, Homma A, Lee BY, Loukas A, Loblack M, Morel CM, Oliveira RC, Russell PK. The Human Hookworm Vaccine. Vaccine. 2013 Apr 18; 31 Suppl 2:B227-32. PMID: 23598487; PMCID: PMC3988917.
    114. Beaumier CM, Gillespie PM, Hotez PJ, Bottazzi ME. New vaccines for neglected parasitic diseases and dengue. Transl Res. 2013 Sep; 162(3):144-55. PMID: 23578479.
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    115. Brindley PJ, Hotez PJ. Break Out: urogenital schistosomiasis and Schistosoma haematobium infection in the post-genomic era. PLoS Negl Trop Dis. 2013; 7(3):e1961. PMID: 23556007; PMCID: PMC3610632.
    116. Hotez PJ, Papageorgiou TD. A new European neglected diseases center for Greece? PLoS Negl Trop Dis. 2013; 7(2):e1757. PMID: 23469292; PMCID: PMC3585001.
    117. Lee BY, Bacon KM, Bottazzi ME, Hotez PJ. Global economic burden of Chagas disease: a computational simulation model. Lancet Infect Dis. 2013 Apr; 13(4):342-8. PMID: 23395248; PMCID: PMC3763184.
    118. Sanghvi MM, Hotez PJ, Fenwick A. Neglected tropical diseases as a cause of chronic liver disease: the case of Schistosomiasis and Hepatitis C Co-infections in Egypt. Liver Int. 2013 Feb; 33(2):165-8. PMID: 23295048.
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    119. Kline K, McCarthy JS, Pearson M, Loukas A, Hotez PJ. Neglected tropical diseases of Oceania: review of their prevalence, distribution, and opportunities for control. PLoS Negl Trop Dis. 2013; 7(1):e1755. PMID: 23383349; PMCID: PMC3561157.
    120. Barry MA, Weatherhead JE, Hotez PJ, Woc-Colburn L. Childhood parasitic infections endemic to the United States. Pediatr Clin North Am. 2013 Apr; 60(2):471-85. PMID: 23481112.
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    121. Hotez PJ, Dumonteil E, Heffernan MJ, Bottazzi ME. Innovation for the 'bottom 100 million': eliminating neglected tropical diseases in the Americas. Adv Exp Med Biol. 2013; 764:1-12. PMID: 23654053.
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    125. Hotez PJ. Engaging a rising China through neglected tropical diseases. PLoS Negl Trop Dis. 2012; 6(11):e1599. PMID: 23209845; PMCID: PMC3510098.
    126. Bacon KM, Hotez PJ, Kruchten SD, Kamhawi S, Bottazzi ME, Valenzuela JG, Lee BY. The potential economic value of a cutaneous leishmaniasis vaccine in seven endemic countries in the Americas. Vaccine. 2013 Jan 7; 31(3):480-6. PMID: 23176979; PMCID: PMC3763201.
    127. Hotez PJ, Aksoy S. Now we are six. PLoS Negl Trop Dis. 2012; 6(10):e1862. PMID: 23145194; PMCID: PMC3493393.
    128. Hotez PJ. Fighting neglected tropical diseases in the southern United States. BMJ. 2012; 345:e6112. PMID: 22977143.
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    129. Dumonteil E, Bottazzi ME, Zhan B, Heffernan MJ, Jones K, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Lee BY, Bacon KM, Fleischer B, Slingsby BT, Cravioto MB, Tapia-Conyer R, Hotez PJ. Accelerating the development of a therapeutic vaccine for human Chagas disease: rationale and prospects. Expert Rev Vaccines. 2012 Sep; 11(9):1043-55. PMID: 23151163; PMCID: PMC3819810.
    130. Lee BY, Bacon KM, Wateska AR, Bottazzi ME, Dumonteil E, Hotez PJ. Modeling the economic value of a Chagas' disease therapeutic vaccine. Hum Vaccin Immunother. 2012 Sep; 8(9):1293-301. PMID: 22894964; PMCID: PMC3579910.
    131. Zhan B, Santiago H, Keegan B, Gillespie P, Xue J, Bethony J, de Oliveira LM, Jiang D, Diemert D, Xiao SH, Jones K, Feng X, Hotez PJ, Bottazzi ME. Fusion of Na-ASP-2 with human immunoglobulin Fc? abrogates histamine release from basophils sensitized with anti-Na-ASP-2 IgE. Parasite Immunol. 2012 Aug-Sep; 34(8-9):404-11. PMID: 22651670.
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    132. Hotez PJ, Asojo OA, Adesina AM. Nigeria: "Ground Zero" for the high prevalence neglected tropical diseases. PLoS Negl Trop Dis. 2012; 6(7):e1600. PMID: 22860138; PMCID: PMC3409117.
    133. Barry MA, Bezek S, Serpa JA, Hotez PJ, Woc-Colburn L. Neglected infections of poverty in Texas and the rest of the United States: management and treatment options. Clin Pharmacol Ther. 2012 Aug; 92(2):170-81. PMID: 22760004.
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    134. Pearson MS, Tribolet L, Cantacessi C, Periago MV, Valero MA, Valerio MA, Jariwala AR, Hotez P, Diemert D, Loukas A, Bethony J. Molecular mechanisms of hookworm disease: stealth, virulence, and vaccines. J Allergy Clin Immunol. 2012 Jul; 130(1):13-21. PMID: 22742835.
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    135. Hotez PJ. The Four Horsemen of the Apocalypse: Tropical Medicine in the Fight against Plague, Death, Famine, and War. Am J Trop Med Hyg. 2012 Jul; 87(1):3-10. PMID: 22764283; PMCID: PMC3391054.
    136. Moolani Y, Bukhman G, Hotez PJ. Neglected tropical diseases as hidden causes of cardiovascular disease. PLoS Negl Trop Dis. 2012; 6(6):e1499. PMID: 22745835; PMCID: PMC3383757.
    137. Hotez PJ, Dumonteil E, Woc-Colburn L, Serpa JA, Bezek S, Edwards MS, Hallmark CJ, Musselwhite LW, Flink BJ, Bottazzi ME. Chagas disease: "the new HIV/AIDS of the Americas". PLoS Negl Trop Dis. 2012; 6(5):e1498. PMID: 22666504; PMCID: PMC3362306.
    138. Diemert DJ, Pinto AG, Freire J, Jariwala A, Santiago H, Hamilton RG, Periago MV, Loukas A, Tribolet L, Mulvenna J, Correa-Oliveira R, Hotez PJ, Bethony JM. Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: implications for the development of vaccines against helminths. J Allergy Clin Immunol. 2012 Jul; 130(1):169-76.e6. PMID: 22633322.
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    139. Plieskatt JL, Rezende WC, Olsen CM, Trefethen JM, Joshi SB, Middaugh CR, Hotez PJ, Bottazzi ME. Advances in vaccines against neglected tropical diseases: enhancing physical stability of a recombinant hookworm vaccine through biophysical and formulation studies. Hum Vaccin Immunother. 2012 Jun; 8(6):765-76. PMID: 22495115.
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    140. Goud GN, Deumic V, Gupta R, Brelsford J, Zhan B, Gillespie P, Plieskatt JL, Tsao EI, Hotez PJ, Bottazzi ME. Expression, purification, and molecular analysis of the Necator americanus glutathione S-transferase 1 (Na-GST-1): a production process developed for a lead candidate recombinant hookworm vaccine antigen. Protein Expr Purif. 2012 Jun; 83(2):145-51. PMID: 22503665.
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    141. Hotez PJ, Bottazzi ME, Dumonteil E, Valenzuela JG, Kamhawi S, Ortega J, Rosales SP, Cravioto MB, Tapia-Conyer R. Texas and Mexico: sharing a legacy of poverty and neglected tropical diseases. PLoS Negl Trop Dis. 2012; 6(3):e1497. PMID: 22479656; PMCID: PMC3313919.
    142. Pearson MS, Pickering DA, McSorley HJ, Bethony JM, Tribolet L, Dougall AM, Hotez PJ, Loukas A. Enhanced protective efficacy of a chimeric form of the schistosomiasis vaccine antigen Sm-TSP-2. PLoS Negl Trop Dis. 2012; 6(3):e1564. PMID: 22428079; PMCID: PMC3302818.
    143. Hotez PJ, Savioli L, Fenwick A. Neglected tropical diseases of the Middle East and North Africa: review of their prevalence, distribution, and opportunities for control. PLoS Negl Trop Dis. 2012; 6(2):e1475. PMID: 22389729; PMCID: PMC3289601.
    144. Mathias DK, Plieskatt JL, Armistead JS, Bethony JM, Abdul-Majid KB, McMillan A, Angov E, Aryee MJ, Zhan B, Gillespie P, Keegan B, Jariwala AR, Rezende W, Bottazzi ME, Scorpio DG, Hotez PJ, Dinglasan RR. Expression, immunogenicity, histopathology, and potency of a mosquito-based malaria transmission-blocking recombinant vaccine. Infect Immun. 2012 Apr; 80(4):1606-14. PMID: 22311924; PMCID: PMC3318422.
    145. Hotez PJ, Aksoy S. An interfaith dialogue on the neglected tropical diseases. PLoS Negl Trop Dis. 2011 Dec; 5(12):e1240. PMID: 22206020; PMCID: PMC3243705.
    146. Hotez P. Enlarging the "Audacious Goal": elimination of the world's high prevalence neglected tropical diseases. Vaccine. 2011 Dec 30; 29 Suppl 4:D104-10. PMID: 22188933.
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    147. Hotez PJ, Goraleski KA. Neglected tropical diseases and the 2012 US presidential election. PLoS Negl Trop Dis. 2011 Nov; 5(11):e1431. PMID: 22140593; PMCID: PMC3226462.
    148. Schneider B, Jariwala AR, Periago MV, Gazzinelli MF, Bose SN, Hotez PJ, Diemert DJ, Bethony JM. A history of hookworm vaccine development. Hum Vaccin. 2011 Nov; 7(11):1234-44. PMID: 22064562; PMCID: PMC3323499.
    149. Lobo DA, Velayudhan R, Chatterjee P, Kohli H, Hotez PJ. The neglected tropical diseases of India and South Asia: review of their prevalence, distribution, and control or elimination. PLoS Negl Trop Dis. 2011 Oct; 5(10):e1222. PMID: 22039553; PMCID: PMC3201909.
    150. Xue J, Zhan B, Guo J, He N, Qiang HQ, Hotez P, Xiao SH. Acquired hookworm immunity in the golden hamster (Mesocricetus auratus) elicited by living Necator americanus third-stage infective larvae. Exp Parasitol. 2012 Jan; 130(1):6-12. PMID: 22024448.
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    151. Hotez PJ, Alibek K. Central Asia's hidden burden of neglected tropical diseases. PLoS Negl Trop Dis. 2011 Sep; 5(9):e1224. PMID: 21980541; PMCID: PMC3181239.
    152. Nair SS, Bommana A, Pakala SB, Ohshiro K, Lyon AJ, Suttiprapa S, Periago MV, Laha T, Hotez PJ, Bethony JM, Sripa B, Brindley PJ, Kumar R. Inflammatory response to liver fluke Opisthorchis viverrini in mice depends on host master coregulator MTA1, a marker for parasite-induced cholangiocarcinoma in humans. Hepatology. 2011 Oct; 54(4):1388-97. PMID: 21725997; PMCID: PMC3184196.
    153. Noblick J, Skolnik R, Hotez PJ. Linking global HIV/AIDS treatments with national programs for the control and elimination of the neglected tropical diseases. PLoS Negl Trop Dis. 2011 Jul; 5(7):e1022. PMID: 21814582; PMCID: PMC3144180.
    154. Hotez PJ, Gurwith M. Europe's neglected infections of poverty. Int J Infect Dis. 2011 Sep; 15(9):e611-9. PMID: 21763173.
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    155. Hotez PJ. Unleashing "civilian power": a new American diplomacy through neglected tropical disease control, elimination, research, and development. PLoS Negl Trop Dis. 2011 Jun; 5(6):e1134. PMID: 21738802; PMCID: PMC3125138.
    156. Loukas A, Gaze S, Mulvenna JP, Gasser RB, Brindley PJ, Doolan DL, Bethony JM, Jones MK, Gobert GN, Driguez P, McManus DP, Hotez PJ. Vaccinomics for the major blood feeding helminths of humans. OMICS. 2011 Sep; 15(9):567-77. PMID: 21679087.
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    157. Nair SS, Bommana A, Bethony JM, Lyon AJ, Ohshiro K, Pakala SB, Rinaldi G, Keegan B, Suttiprapa S, Periago MV, Hotez PJ, Brindley PJ, Kumar R. The metastasis-associated protein-1 gene encodes a host permissive factor for schistosomiasis, a leading global cause of inflammation and cancer. Hepatology. 2011 Jul; 54(1):285-95. PMID: 21488078; PMCID: PMC3125413.
    158. Hotez PJ, Mistry N, Rubinstein J, Sachs JD. Integrating neglected tropical diseases into AIDS, tuberculosis, and malaria control. N Engl J Med. 2011 Jun 2; 364(22):2086-9. PMID: 21631320.
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    159. Hotez P. A handful of 'antipoverty' vaccines exist for neglected diseases, but the world's poorest billion people need more. Health Aff (Millwood). 2011 Jun; 30(6):1080-7. PMID: 21653960.
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    160. Hotez PJ. New antipoverty drugs, vaccines, and diagnostics: a research agenda for the US President's Global Health Initiative (GHI). PLoS Negl Trop Dis. 2011; 5(5):e1133. PMID: 21655348; PMCID: PMC3104954.
    161. Hotez PJ. Neglected tropical diseases in the Catholic world. PLoS Negl Trop Dis. 2011; 5(4):e1132. PMID: 21541361; PMCID: PMC3082513.
    162. Hotez PJ. America's most distressed areas and their neglected infections: the United States Gulf Coast and the District of Columbia. PLoS Negl Trop Dis. 2011; 5(3):e843. PMID: 21468312; PMCID: PMC3066143.
    163. Alexander N, Cundill B, Sabatelli L, Bethony JM, Diemert D, Hotez P, Smith PG, Rodrigues LC, Brooker S. Selection and quantification of infection endpoints for trials of vaccines against intestinal helminths. Vaccine. 2011 May 9; 29(20):3686-94. PMID: 21435404; PMCID: PMC3093614.
    164. Jiang D, Zhan B, Mayor RS, Gillespie P, Keegan B, Bottazzi ME, Hotez P. Ac-AP-12, a novel factor Xa anticoagulant peptide from the esophageal glands of adult Ancylostoma caninum. Mol Biochem Parasitol. 2011 May; 177(1):42-8. PMID: 21251931.
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    165. Bethony JM, Cole RN, Guo X, Kamhawi S, Lightowlers MW, Loukas A, Petri W, Reed S, Valenzuela JG, Hotez PJ. Vaccines to combat the neglected tropical diseases. Immunol Rev. 2011 Jan; 239(1):237-70. PMID: 21198676; PMCID: PMC3438653.
    166. Jex AR, Lim YA, Bethony JM, Hotez PJ, Young ND, Gasser RB. Soil-transmitted helminths of humans in Southeast Asia--towards integrated control. Adv Parasitol. 2011; 74:231-65. PMID: 21295679.
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    167. Bourhy H, Dautry-Varsat A, Hotez PJ, Salomon J. Rabies, still neglected after 125 years of vaccination. PLoS Negl Trop Dis. 2010; 4(11):e839. PMID: 21152052; PMCID: PMC2994912.
    168. Hotez PJ, Bethony JM, Diemert DJ, Pearson M, Loukas A. Developing vaccines to combat hookworm infection and intestinal schistosomiasis. Nat Rev Microbiol. 2010 Nov; 8(11):814-26. PMID: 20948553.
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    169. Jariwala AR, Oliveira LM, Diemert DJ, Keegan B, Plieskatt JL, Periago MV, Bottazzi ME, Hotez PJ, Bethony JM. Potency testing for the experimental Na-GST-1 hookworm vaccine. Expert Rev Vaccines. 2010 Oct; 9(10):1219-30. PMID: 20923271.
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    170. Hotez PJ. Neglected tropical disease control in the "post-American world". PLoS Negl Trop Dis. 2010; 4(8). PMID: 20824178; PMCID: PMC2930879.
    171. Hotez PJ, Engels D, Fenwick A, Savioli L. Africa is desperate for praziquantel. Lancet. 2010 Aug 14; 376(9740):496-8. PMID: 20709217.
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    172. Brooker S, Hotez PJ, Bundy DA. The global atlas of helminth infection: mapping the way forward in neglected tropical disease control. PLoS Negl Trop Dis. 2010; 4(7):e779. PMID: 20668545; PMCID: PMC2910703.
    173. Sripa B, Bethony JM, Sithithaworn P, Kaewkes S, Mairiang E, Loukas A, Mulvenna J, Laha T, Hotez PJ, Brindley PJ. Opisthorchiasis and Opisthorchis-associated cholangiocarcinoma in Thailand and Laos. Acta Trop. 2011 Sep; 120 Suppl 1:S158-68. PMID: 20655862; PMCID: PMC3010517.
    174. Hotez P. A national school of tropical medicine and neglected infections of poverty for North America. PLoS Negl Trop Dis. 2010; 4(6):e735. PMID: 20614018; PMCID: PMC2894135.
    175. Hotez PJ, Pecoul B. "Manifesto" for advancing the control and elimination of neglected tropical diseases. PLoS Negl Trop Dis. 2010; 4(5):e718. PMID: 20520793; PMCID: PMC2876053.
    176. Spiegel JM, Dharamsi S, Wasan KM, Yassi A, Singer B, Hotez PJ, Hanson C, Bundy DA. Which new approaches to tackling neglected tropical diseases show promise? PLoS Med. 2010 May; 7(5):e1000255. PMID: 20502599; PMCID: PMC2872649.
    177. Pearson MS, Pickering DA, Tribolet L, Cooper L, Mulvenna J, Oliveira LM, Bethony JM, Hotez PJ, Loukas A. Neutralizing antibodies to the hookworm hemoglobinase Na-APR-1: implications for a multivalent vaccine against hookworm infection and schistosomiasis. J Infect Dis. 2010 May 15; 201(10):1561-9. PMID: 20367477.
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    178. Hotez P, Stillwaggon E, McDonald M, Todman L, DiGrazia L. National summit on neglected infections of poverty in the United States. Emerg Infect Dis. 2010 May; 16(5):e1. PMID: 20409362; PMCID: PMC2954013.
    179. Hotez PJ. Nuclear weapons and neglected diseases: the "ten-thousand-to-one gap". PLoS Negl Trop Dis. 2010; 4(4):e680. PMID: 20436916; PMCID: PMC2860509.
    180. Hotez PJ. Peace through vaccine diplomacy. Science. 2010 Mar 12; 327(5971):1301. PMID: 20223952.
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    181. Kishore SP, Tavera G, Hotez PJ. The global health crisis and our nation's research universities. PLoS Negl Trop Dis. 2010; 4(2):e635. PMID: 20186327; PMCID: PMC2826404.
    182. Zhan B, Perally S, Brophy PM, Xue J, Goud G, Liu S, Deumic V, de Oliveira LM, Bethony J, Bottazzi ME, Jiang D, Gillespie P, Xiao SH, Gupta R, Loukas A, Ranjit N, Lustigman S, Oksov Y, Hotez P. Molecular cloning, biochemical characterization, and partial protective immunity of the heme-binding glutathione S-transferases from the human hookworm Necator americanus. Infect Immun. 2010 Apr; 78(4):1552-63. PMID: 20145100; PMCID: PMC2849424.
    183. Hotez PJ. Neglected infections of poverty among the indigenous peoples of the arctic. PLoS Negl Trop Dis. 2010; 4(1):e606. PMID: 20126272; PMCID: PMC2811175.
    184. Hotez PJ, Ehrenberg JP. Escalating the global fight against neglected tropical diseases through interventions in the Asia Pacific region. Adv Parasitol. 2010; 72:31-53. PMID: 20624527.
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    185. Hotez PJ. A plan to defeat neglected tropical diseases. Sci Am. 2010 Jan; 302(1):90-4, 96. PMID: 20063641.
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    186. Hotez PJ. Empowering women and improving female reproductive health through control of neglected tropical diseases. PLoS Negl Trop Dis. 2009; 3(11):e559. PMID: 19936248; PMCID: PMC2775907.
    187. Hotez P. Neglected diseases amid wealth in the United States and Europe. Health Aff (Millwood). 2009 Nov-Dec; 28(6):1720-5. PMID: 19887412.
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    188. Musgrove P, Hotez PJ. Turning neglected tropical diseases into forgotten maladies. Health Aff (Millwood). 2009 Nov-Dec; 28(6):1691-706. PMID: 19887410.
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    189. Hotez PJ. The neglected tropical diseases and their devastating health and economic impact on the member nations of the Organisation of the Islamic Conference. PLoS Negl Trop Dis. 2009; 3(10):e539. PMID: 19859530; PMCID: PMC2760759.
    190. Hotez PJ, Fenwick A. Schistosomiasis in Africa: an emerging tragedy in our new global health decade. PLoS Negl Trop Dis. 2009; 3(9):e485. PMID: 19787054; PMCID: PMC2746322.
    191. Hotez PJ. A constitutional amendment for deworming. PLoS Negl Trop Dis. 2009; 3(8):e454. PMID: 19707577; PMCID: PMC2726627.
    192. Hotez PJ, Kamath A. Neglected tropical diseases in sub-saharan Africa: review of their prevalence, distribution, and disease burden. PLoS Negl Trop Dis. 2009; 3(8):e412. PMID: 19707588; PMCID: PMC2727001.
    193. Franco-Paredes C, Bottazzi ME, Hotez PJ. The unfinished public health agenda of chagas disease in the era of globalization. PLoS Negl Trop Dis. 2009; 3(7):e470. PMID: 19582139; PMCID: PMC2700253.
    194. Stoever K, Molyneux D, Hotez P, Fenwick A. HIV/AIDS, schistosomiasis, and girls. Lancet. 2009 Jun 13; 373(9680):2025-6. PMID: 19524778.
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    195. Hotez PJ, Fenwick A, Kjetland EF. Africa's 32 cents solution for HIV/AIDS. PLoS Negl Trop Dis. 2009; 3(5):e430. PMID: 19479041; PMCID: PMC2682705.
    196. Hotez PJ, Fenwick A, Savioli L, Molyneux DH. Rescuing the bottom billion through control of neglected tropical diseases. Lancet. 2009 May 2; 373(9674):1570-5. PMID: 19410718.
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    197. Hotez PJ. One world health: neglected tropical diseases in a flat world. PLoS Negl Trop Dis. 2009; 3(4):e405. PMID: 19399165; PMCID: PMC2668801.
    198. Pearson MS, Bethony JM, Pickering DA, de Oliveira LM, Jariwala A, Santiago H, Miles AP, Zhan B, Jiang D, Ranjit N, Mulvenna J, Tribolet L, Plieskatt J, Smith T, Bottazzi ME, Jones K, Keegan B, Hotez PJ, Loukas A. An enzymatically inactivated hemoglobinase from Necator americanus induces neutralizing antibodies against multiple hookworm species and protects dogs against heterologous hookworm infection. FASEB J. 2009 Sep; 23(9):3007-19. PMID: 19380510; PMCID: PMC2735369.
    199. Hotez PJ, Wilkins PP. Toxocariasis: America's most common neglected infection of poverty and a helminthiasis of global importance? PLoS Negl Trop Dis. 2009; 3(3):e400. PMID: 19333373; PMCID: PMC2658740.
    200. Hotez PJ. Mass drug administration and integrated control for the world's high-prevalence neglected tropical diseases. Clin Pharmacol Ther. 2009 Jun; 85(6):659-64. PMID: 19322166.
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    201. Hotez PJ, Brown AS. Neglected tropical disease vaccines. Biologicals. 2009 Jun; 37(3):160-4. PMID: 19278869.
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    202. Ranjit N, Zhan B, Hamilton B, Stenzel D, Lowther J, Pearson M, Gorman J, Hotez P, Loukas A. Proteolytic degradation of hemoglobin in the intestine of the human hookworm Necator americanus. J Infect Dis. 2009 Mar 15; 199(6):904-12. PMID: 19434933.
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    203. Hotez PJ, Thompson TG. Waging peace through neglected tropical disease control: a US foreign policy for the bottom billion. PLoS Negl Trop Dis. 2009; 3(1):e346. PMID: 19172176; PMCID: PMC2625433.
    204. Molyneux DH, Hotez PJ, Fenwick A, Newman RD, Greenwood B, Sachs J. Neglected tropical diseases and the Global Fund. Lancet. 2009 Jan 24; 373(9660):296-7. PMID: 19167564.
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    205. Andrus JK, de Quadros C, Matus CR, Luciani S, Hotez P. New vaccines for developing countries: will it be feast or famine? Am J Law Med. 2009; 35(2-3):311-22. PMID: 19697751.
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    206. Hotez PJ. Tropical diseases research: thirty years and counting. PLoS Negl Trop Dis. 2008; 2(11):e329. PMID: 19030224; PMCID: PMC2582687.
    207. Sabatelli L, Ghani AC, Rodrigues LC, Hotez PJ, Brooker S. Modelling heterogeneity and the impact of chemotherapy and vaccination against human hookworm. J R Soc Interface. 2008 Nov 6; 5(28):1329-41. PMID: 18331978; PMCID: PMC2607437.
    208. Hotez PJ, Daar AS. The CNCDs and the NTDs: blurring the lines dividing noncommunicable and communicable chronic diseases. PLoS Negl Trop Dis. 2008; 2(10):e312. PMID: 18958154; PMCID: PMC2568818.
    209. Hotez PJ, Bottazzi ME, Franco-Paredes C, Ault SK, Periago MR. The neglected tropical diseases of Latin America and the Caribbean: a review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl Trop Dis. 2008; 2(9):e300. PMID: 18820747; PMCID: PMC2553488.
    210. Brooker S, Hotez PJ, Bundy DA. Hookworm-related anaemia among pregnant women: a systematic review. PLoS Negl Trop Dis. 2008; 2(9):e291. PMID: 18820740; PMCID: PMC2553481.
    211. Zhan B, Gupta R, Wong SP, Bier S, Jiang D, Goud G, Hotez P. Molecular cloning and characterization of Ac-TMP-2, a tissue inhibitor of metalloproteinase secreted by adult Ancylostoma caninum. Mol Biochem Parasitol. 2008 Dec; 162(2):142-8. PMID: 18804124.
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    212. Hotez PJ. Training the next generation of global health scientists: a school of appropriate technology for global health. PLoS Negl Trop Dis. 2008; 2(8):e279. PMID: 18846232; PMCID: PMC2565696.
    213. Hotez PJ, Bethony JM, Oliveira SC, Brindley PJ, Loukas A. Multivalent anthelminthic vaccine to prevent hookworm and schistosomiasis. Expert Rev Vaccines. 2008 Aug; 7(6):745-52. PMID: 18665774.
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    214. Hotez PJ, Molyneux DH. Tropical anemia: one of Africa's great killers and a rationale for linking malaria and neglected tropical disease control to achieve a common goal. PLoS Negl Trop Dis. 2008; 2(7):e270. PMID: 18665256; PMCID: PMC2474697.
    215. Hotez PJ. Neglected infections of poverty in the United States of America. PLoS Negl Trop Dis. 2008; 2(6):e256. PMID: 18575621; PMCID: PMC2430531.
    216. Hotez PJ. Holidays in the sun and the Caribbean's forgotten burden of neglected tropical diseases. PLoS Negl Trop Dis. 2008; 2(5):e239. PMID: 18509471; PMCID: PMC2386240.
    217. Hotez PJ. Stigma: the stealth weapon of the NTD. PLoS Negl Trop Dis. 2008; 2(4):e230. PMID: 18446206; PMCID: PMC2322832.
    218. Ranjit N, Zhan B, Stenzel DJ, Mulvenna J, Fujiwara R, Hotez PJ, Loukas A. A family of cathepsin B cysteine proteases expressed in the gut of the human hookworm, Necator americanus. Mol Biochem Parasitol. 2008 Aug; 160(2):90-9. PMID: 18501979.
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    219. Hotez PJ, Brindley PJ, Bethony JM, King CH, Pearce EJ, Jacobson J. Helminth infections: the great neglected tropical diseases. J Clin Invest. 2008 Apr; 118(4):1311-21. PMID: 18382743; PMCID: PMC2276811.
    220. Hotez PJ, Molyneux DH, Fenwick A, Savioli L, Takeuchi T. A Global Fund to Fight Neglected Tropical Diseases: is the G8 Hokkaido Toyako 2008 Summit ready? PLoS Negl Trop Dis. 2008; 2(3):e220. PMID: 18365038; PMCID: PMC2268747.
    221. Bethony JM, Simon G, Diemert DJ, Parenti D, Desrosiers A, Schuck S, Fujiwara R, Santiago H, Hotez PJ. Randomized, placebo-controlled, double-blind trial of the Na-ASP-2 hookworm vaccine in unexposed adults. Vaccine. 2008 May 2; 26(19):2408-17. PMID: 18396361.
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    222. Hotez PJ. Reinventing Guantanamo: from detainee facility to Center for Research on Neglected Diseases of Poverty in the Americas. PLoS Negl Trop Dis. 2008; 2(2):e201. PMID: 18301728; PMCID: PMC2254199.
    223. Hotez PJ. The giant anteater in the room: Brazil's neglected tropical diseases problem. PLoS Negl Trop Dis. 2008; 2(1):e177. PMID: 18327292; PMCID: PMC2265550.
    224. Diemert DJ, Bethony JM, Hotez PJ. Hookworm vaccines. Clin Infect Dis. 2008 Jan 15; 46(2):282-8. PMID: 18171264.
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    225. Mendez S, D' Samuel A, Antoine AD, Ahn S, Hotez P. Use of the air pouch model to investigate immune responses to a hookworm vaccine containing the Na-ASP-2 protein in rats. Parasite Immunol. 2008 Jan; 30(1):53-6. PMID: 18086017.
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    226. Hotez PJ. Neglected diseases and poverty in "The Other America": the greatest health disparity in the United States? PLoS Negl Trop Dis. 2007; 1(3):e149. PMID: 18160982; PMCID: PMC2154393.
    227. Brooker S, Akhwale W, Pullan R, Estambale B, Clarke SE, Snow RW, Hotez PJ. Epidemiology of plasmodium-helminth co-infection in Africa: populations at risk, potential impact on anemia, and prospects for combining control. Am J Trop Med Hyg. 2007 Dec; 77(6 Suppl):88-98. PMID: 18165479; PMCID: PMC2637949.
    228. Hotez P. Measuring neglect. PLoS Negl Trop Dis. 2007; 1(2):e118. PMID: 18060078; PMCID: PMC2100377.
    229. Hotez P. A new voice for the poor. PLoS Negl Trop Dis. 2007; 1(1):e77. PMID: 17989790; PMCID: PMC2041819.
    230. Hotez P, Raff S, Fenwick A, Richards F, Molyneux DH. Recent progress in integrated neglected tropical disease control. Trends Parasitol. 2007 Nov; 23(11):511-4. PMID: 17951109.
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    231. Hotez P. Hookworm and poverty. Ann N Y Acad Sci. 2008; 1136:38-44. PMID: 17954674.
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    232. Hotez PJ, Molyneux DH, Fenwick A, Kumaresan J, Sachs SE, Sachs JD, Savioli L. Control of neglected tropical diseases. N Engl J Med. 2007 Sep 6; 357(10):1018-27. PMID: 17804846.
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    233. Alexander N, Bethony J, Corrêa-Oliveira R, Rodrigues LC, Hotez P, Brooker S. Repeatability of paired counts. Stat Med. 2007 Aug 30; 26(19):3566-77. PMID: 17091531.
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    234. Yamey G, Hotez P. Neglected tropical diseases. BMJ. 2007 Aug 11; 335(7614):269-70. PMID: 17690342; PMCID: PMC1941851.
    235. Asojo OA, Homma K, Sedlacek M, Ngamelue M, Goud GN, Zhan B, Deumic V, Asojo O, Hotez PJ. X-ray structures of Na-GST-1 and Na-GST-2 two glutathione S-transferase from the human hookworm Necator americanus. BMC Struct Biol. 2007; 7:42. PMID: 17594497; PMCID: PMC1924862.
    236. Hotez PJ. Control of onchocerciasis--the next generation. Lancet. 2007 Jun 16; 369(9578):1979-80. PMID: 17574078.
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    237. Xiao S, Zhan B, Xue J, Goud GN, Loukas A, Liu Y, Williamson A, Liu S, Deumic V, Hotez P. The evaluation of recombinant hookworm antigens as vaccines in hamsters (Mesocricetus auratus) challenged with human hookworm, Necator americanus. Exp Parasitol. 2008 Jan; 118(1):32-40. PMID: 17645877.
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    238. Fujiwara RT, Zhan B, Mendez S, Loukas A, Bueno LL, Wang Y, Plieskatt J, Oksov Y, Lustigman S, Bottazzi ME, Hotez P, Bethony JM. Reduction of worm fecundity and canine host blood loss mediates protection against hookworm infection elicited by vaccination with recombinant Ac-16. Clin Vaccine Immunol. 2007 Mar; 14(3):281-7. PMID: 17267592; PMCID: PMC1828853.
    239. Feng J, Zhan B, Liu Y, Liu S, Williamson A, Goud G, Loukas A, Hotez P. Molecular cloning and characterization of Ac-MTP-2, an astacin-like metalloprotease released by adult Ancylostoma caninum. Mol Biochem Parasitol. 2007 Apr; 152(2):132-8. PMID: 17280728.
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    240. Inan M, Fanders SA, Zhang W, Hotez PJ, Zhan B, Meagher MM. Saturation of the secretory pathway by overexpression of a hookworm (Necator americanus) Protein (Na-ASP1). Methods Mol Biol. 2007; 389:65-76. PMID: 17951635.
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    241. Hotez PJ, Molyneux DH, Stillwaggon E, Bentwich Z, Kumaresan J. Neglected tropical diseases and HIV/AIDS. Lancet. 2006 Nov 25; 368(9550):1865-6. PMID: 17126708.
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    242. Brooker S, Clements AC, Hotez PJ, Hay SI, Tatem AJ, Bundy DA, Snow RW. The co-distribution of Plasmodium falciparum and hookworm among African schoolchildren. Malar J. 2006; 5:99. PMID: 17083720; PMCID: PMC1635726.
    243. Loukas A, Bethony J, Brooker S, Hotez P. Hookworm vaccines: past, present, and future. Lancet Infect Dis. 2006 Nov; 6(11):733-41. PMID: 17067922.
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    244. Brooker S, Jardim-Botelho A, Quinnell RJ, Geiger SM, Caldas IR, Fleming F, Hotez PJ, Correa-Oliveira R, Rodrigues LC, Bethony JM. Age-related changes in hookworm infection, anaemia and iron deficiency in an area of high Necator americanus hookworm transmission in south-eastern Brazil. Trans R Soc Trop Med Hyg. 2007 Feb; 101(2):146-54. PMID: 17027054.
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    245. Jian X, Jun-Min Y, Hai-Chou X, Hui-Qing Q, Hai-Nan R, Hotez P, Bin Z, Shu-Hua X. Protective immunity elicited by ultraviolet-irradiated third-stage infective hookworm (Necator americanus and Ancylostoma caninum) larvae in mice and hamsters. Southeast Asian J Trop Med Public Health. 2006 Sep; 37(5):885-95. PMID: 17333729.
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    246. Brooker S, Alexander N, Geiger S, Moyeed RA, Stander J, Fleming F, Hotez PJ, Correa-Oliveira R, Bethony J. Contrasting patterns in the small-scale heterogeneity of human helminth infections in urban and rural environments in Brazil. Int J Parasitol. 2006 Sep; 36(10-11):1143-51. PMID: 16814294; PMCID: PMC1783908.
    247. Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Diemert D, Loukas A. New technologies for the control of human hookworm infection. Trends Parasitol. 2006 Jul; 22(7):327-31. PMID: 16709466.
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    248. Hotez PJ, Ferris MT. The antipoverty vaccines. Vaccine. 2006 Jul 26; 24(31-32):5787-99. PMID: 16759763.
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    249. Bethony J, Brooker S, Albonico M, Geiger SM, Loukas A, Diemert D, Hotez PJ. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet. 2006 May 6; 367(9521):1521-32. PMID: 16679166.
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    250. Bottazzi ME, Miles AP, Diemert D, Hotez PJ. An ounce of prevention on a budget: a nonprofit approach to developing vaccines against neglected diseases. Expert Rev Vaccines. 2006 Apr; 5(2):189-98. PMID: 16608419.
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    251. Sachs JD, Hotez PJ. Fighting tropical diseases. Science. 2006 Mar 17; 311(5767):1521. PMID: 16543418.
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    252. Hotez P, Stoever K, Fenwick A, Molyneux D, Savioli L. The Lancet's chronic diseases series. Lancet. 2006 Feb 18; 367(9510):563-4; author reply 564-5. PMID: 16488790.
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    253. Hotez P, Gupta R, Mahoney R, Poste G. Incorporating appropriate technology into North American schools of public health. Rev Panam Salud Publica. 2006 Feb; 19(2):118-23. PMID: 16551386.
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    254. Williamson AL, Lustigman S, Oksov Y, Deumic V, Plieskatt J, Mendez S, Zhan B, Bottazzi ME, Hotez PJ, Loukas A. Ancylostoma caninum MTP-1, an astacin-like metalloprotease secreted by infective hookworm larvae, is involved in tissue migration. Infect Immun. 2006 Feb; 74(2):961-7. PMID: 16428741; PMCID: PMC1360348.
    255. Fleming FM, Brooker S, Geiger SM, Caldas IR, Correa-Oliveira R, Hotez PJ, Bethony JM. Synergistic associations between hookworm and other helminth species in a rural community in Brazil. Trop Med Int Health. 2006 Jan; 11(1):56-64. PMID: 16398756.
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    256. Hotez P, Ottesen E, Fenwick A, Molyneux D. The neglected tropical diseases: the ancient afflictions of stigma and poverty and the prospects for their control and elimination. Adv Exp Med Biol. 2006; 582:23-33. PMID: 16802616.
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    257. Hotez PJ, Molyneux DH, Fenwick A, Ottesen E, Ehrlich Sachs S, Sachs JD. Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Med. 2006 Jan; 3(5):e102. PMID: 16435908; PMCID: PMC1351920.
    258. Bethony JM, Loukas A, Hotez PJ, Knox DP. Vaccines against blood-feeding nematodes of humans and livestock. Parasitology. 2006; 133 Suppl:S63-79. PMID: 17274849.
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    259. Ghosh K, Wu W, Antoine AD, Bottazzi ME, Valenzuela JG, Hotez PJ, Mendez S. The impact of concurrent and treated Ancylostoma ceylanicum hookworm infections on the immunogenicity of a recombinant hookworm vaccine in hamsters. J Infect Dis. 2006 Jan 1; 193(1):155-62. PMID: 16323144.
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    260. Molyneux DH, Hotez PJ, Fenwick A. "Rapid-impact interventions": how a policy of integrated control for Africa's neglected tropical diseases could benefit the poor. PLoS Med. 2005 Nov; 2(11):e336. PMID: 16212468; PMCID: PMC1253619.
    261. Loukas A, Bethony JM, Mendez S, Fujiwara RT, Goud GN, Ranjit N, Zhan B, Jones K, Bottazzi ME, Hotez PJ. Vaccination with recombinant aspartic hemoglobinase reduces parasite load and blood loss after hookworm infection in dogs. PLoS Med. 2005 Oct; 2(10):e295. PMID: 16231975; PMCID: PMC1240050.
    262. Zhan B, Liu S, Perally S, Xue J, Fujiwara R, Brophy P, Xiao S, Liu Y, Feng J, Williamson A, Wang Y, Bueno LL, Mendez S, Goud G, Bethony JM, Hawdon JM, Loukas A, Jones K, Hotez PJ. Biochemical characterization and vaccine potential of a heme-binding glutathione transferase from the adult hookworm Ancylostoma caninum. Infect Immun. 2005 Oct; 73(10):6903-11. PMID: 16177370; PMCID: PMC1230892.
    263. Xue J, Hui-Qing Q, Jun-Ming Y, Fujiwara R, Zhan B, Hotez P, Shu-Hua X. Necator americanus: optimization of the golden hamster model for testing anthelmintic drugs. Exp Parasitol. 2005 Dec; 111(4):219-23. PMID: 16198341.
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    264. Goud GN, Bottazzi ME, Zhan B, Mendez S, Deumic V, Plieskatt J, Liu S, Wang Y, Bueno L, Fujiwara R, Samuel A, Ahn SY, Solanki M, Asojo OA, Wang J, Bethony JM, Loukas A, Roy M, Hotez PJ. Expression of the Necator americanus hookworm larval antigen Na-ASP-2 in Pichia pastoris and purification of the recombinant protein for use in human clinical trials. Vaccine. 2005 Sep 15; 23(39):4754-64. PMID: 16054275.
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    265. Fujiwara RT, Loukas A, Mendez S, Williamson AL, Bueno LL, Wang Y, Samuel A, Zhan B, Bottazzi ME, Hotez PJ, Bethony JM. Vaccination with irradiated Ancylostoma caninum third stage larvae induces a Th2 protective response in dogs. Vaccine. 2006 Jan 23; 24(4):501-9. PMID: 16140437.
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    266. Bethony J, Loukas A, Smout M, Brooker S, Mendez S, Plieskatt J, Goud G, Bottazzi ME, Zhan B, Wang Y, Williamson A, Lustigman S, Correa-Oliveira R, Xiao S, Hotez PJ. Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB J. 2005 Oct; 19(12):1743-5. PMID: 16037096.
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    267. Morel CM, Acharya T, Broun D, Dangi A, Elias C, Ganguly NK, Gardner CA, Gupta RK, Haycock J, Heher AD, Hotez PJ, Kettler HE, Keusch GT, Krattiger AF, Kreutz FT, Lall S, Lee K, Mahoney R, Martinez-Palomo A, Mashelkar RA, Matlin SA, Mzimba M, Oehler J, Ridley RG, Senanayake P, Singer P, Yun M. Health innovation networks to help developing countries address neglected diseases. Science. 2005 Jul 15; 309(5733):401-4. PMID: 16020723.
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    268. Hotez P, Bethony J, Brooker S, Albonico M. Eliminating neglected diseases in Africa. Lancet. 2005 Jun 18-24; 365(9477):2089. PMID: 15964442.
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    269. Mendez S, Valenzuela JG, Wu W, Hotez PJ. Host cytokine production, lymphoproliferation, and antibody responses during the course of Ancylostoma ceylanicum infection in the Golden Syrian hamster. Infect Immun. 2005 Jun; 73(6):3402-7. PMID: 15908367; PMCID: PMC1111885.
    270. Fujiwara RT, Bethony J, Bueno LL, Wang Y, Ahn SY, Samuel A, Bottazzi ME, Hotez P, Mendez S. Immunogenicity of the hookworm Na-ASP-2 vaccine candidate: characterization of humoral and cellular responses after vaccination in the Sprague Dawley rat. Hum Vaccin. 2005 May-Jun; 1(3):123-8. PMID: 17012856.
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    271. Mendez S, Zhan B, Goud G, Ghosh K, Dobardzic A, Wu W, Liu S, Deumic V, Dobardzic R, Liu Y, Bethony J, Hotez PJ. Effect of combining the larval antigens Ancylostoma secreted protein 2 (ASP-2) and metalloprotease 1 (MTP-1) in protecting hamsters against hookworm infection and disease caused by Ancylostoma ceylanicum. Vaccine. 2005 May 2; 23(24):3123-30. PMID: 15837211.
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    272. Hotez PJ, Bethony J, Bottazzi ME, Brooker S, Buss P. Hookworm: "the great infection of mankind". PLoS Med. 2005 Mar; 2(3):e67. PMID: 15783256; PMCID: PMC1069663.
    273. Hotez PJ, Arora S, Bethony J, Bottazzi ME, Loukas A, Correa-Oliveira R, Brooker S. Helminth infections of children: prospects for control. Adv Exp Med Biol. 2005; 568:135-44. PMID: 16108129.
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    274. Hotez PJ, Brooker S, Bethony JM, Bottazzi ME, Loukas A, Xiao S. Hookworm infection. N Engl J Med. 2004 Aug 19; 351(8):799-807. PMID: 15317893.
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    275. Hsieh GC, Loukas A, Wahl AM, Bhatia M, Wang Y, Williamson AL, Kehn KW, Maruyama H, Hotez PJ, Leitenberg D, Bethony J, Constant SL. A secreted protein from the human hookworm necator americanus binds selectively to NK cells and induces IFN-gamma production. J Immunol. 2004 Aug 15; 173(4):2699-704. PMID: 15294988.
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    276. Hotez PJ. Should we establish a North American school of global health sciences? Am J Med Sci. 2004 Aug; 328(2):71-7. PMID: 15311164.
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    277. Don TA, Jones MK, Smyth D, O'Donoghue P, Hotez P, Loukas A. A pore-forming haemolysin from the hookworm, Ancylostoma caninum. Int J Parasitol. 2004 Aug; 34(9):1029-35. PMID: 15313129.
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    278. Zhan B, Wang Y, Liu Y, Williamson A, Loukas A, Hawdon JM, Xue HC, Xiao SH, Hotez PJ. Ac-SAA-1, an immunodominant 16 kDa surface-associated antigen of infective larvae and adults of Ancylostoma caninum. Int J Parasitol. 2004 Aug; 34(9):1037-45. PMID: 15313130.
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    279. Williamson AL, Lecchi P, Turk BE, Choe Y, Hotez PJ, McKerrow JH, Cantley LC, Sajid M, Craik CS, Loukas A. A multi-enzyme cascade of hemoglobin proteolysis in the intestine of blood-feeding hookworms. J Biol Chem. 2004 Aug 20; 279(34):35950-7. PMID: 15199048.
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    280. Hotez PJ. The National Institutes of Health roadmap and the developing world. J Investig Med. 2004 May; 52(4):246-7. PMID: 15521545.
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    281. Loukas A, Bethony JM, Williamson AL, Goud GN, Mendez S, Zhan B, Hawdon JM, Elena Bottazzi M, Brindley PJ, Hotez PJ. Vaccination of dogs with a recombinant cysteine protease from the intestine of canine hookworms diminishes the fecundity and growth of worms. J Infect Dis. 2004 May 15; 189(10):1952-61. PMID: 15122534.
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    282. Hotez PJ, Remme JH, Buss P, Alleyne G, Morel C, Breman JG. Combating tropical infectious diseases: report of the Disease Control Priorities in Developing Countries Project. Clin Infect Dis. 2004 Mar 15; 38(6):871-8. PMID: 14999633.
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    283. Goud GN, Zhan B, Ghosh K, Loukas A, Hawdon J, Dobardzic A, Deumic V, Liu S, Dobardzic R, Zook BC, Jin Q, Liu Y, Hoffman L, Chung-Debose S, Patel R, Mendez S, Hotez PJ. Cloning, yeast expression, isolation, and vaccine testing of recombinant Ancylostoma-secreted protein (ASP)-1 and ASP-2 from Ancylostoma ceylanicum. J Infect Dis. 2004 Mar 1; 189(5):919-29. PMID: 14976610.
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    284. Brooker S, Bethony J, Hotez PJ. Human hookworm infection in the 21st century. Adv Parasitol. 2004; 58:197-288. PMID: 15603764; PMCID: PMC2268732.
    285. de Silva NR, Brooker S, Hotez PJ, Montresor A, Engels D, Savioli L. Soil-transmitted helminth infections: updating the global picture. Trends Parasitol. 2003 Dec; 19(12):547-51. PMID: 14642761.
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    286. Jian X, Shu-Hua X, Hui-Qing Q, Sen L, Hotez P, Bing-Gui S, Hai-Chou X, Tie-Hua L, Bin Z. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). II. Morphological development of the adult and its comparison with humans. Exp Parasitol. 2003 Nov-Dec; 105(3-4):192-200. PMID: 14990312.
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    287. Hotez PJ, Zhan B, Bethony JM, Loukas A, Williamson A, Goud GN, Hawdon JM, Dobardzic A, Dobardzic R, Ghosh K, Bottazzi ME, Mendez S, Zook B, Wang Y, Liu S, Essiet-Gibson I, Chung-Debose S, Xiao S, Knox D, Meagher M, Inan M, Correa-Oliveira R, Vilk P, Shepherd HR, Brandt W, Russell PK. Progress in the development of a recombinant vaccine for human hookworm disease: the Human Hookworm Vaccine Initiative. Int J Parasitol. 2003 Sep 30; 33(11):1245-58. PMID: 13678639.
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    288. Williamson AL, Brindley PJ, Knox DP, Hotez PJ, Loukas A. Digestive proteases of blood-feeding nematodes. Trends Parasitol. 2003 Sep; 19(9):417-23. PMID: 12957519.
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    289. Zhan B, Liu Y, Badamchian M, Williamson A, Feng J, Loukas A, Hawdon JM, Hotez PJ. Molecular characterisation of the Ancylostoma-secreted protein family from the adult stage of Ancylostoma caninum. Int J Parasitol. 2003 Aug; 33(9):897-907. PMID: 12906874.
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    290. Hotez PJ, Ashcom J, Zhan B, Bethony J, Loukas A, Hawdon J, Wang Y, Jin Q, Jones KC, Dobardzic A, Dobardzic R, Bolden J, Essiet I, Brandt W, Russell PK, Zook BC, Howard B, Chacon M. Effect of vaccination with a recombinant fusion protein encoding an astacinlike metalloprotease (MTP-1) secreted by host-stimulated Ancylostoma caninum third-stage infective larvae. J Parasitol. 2003 Aug; 89(4):853-5. PMID: 14533704.
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    291. Hotez PJ. Erosion of William Henry Welch's concept of the hygienic laboratory in our nation's schools of public health and medicine. Public Health Rep. 2003 May-Jun; 118(3):184-6. PMID: 12766211; PMCID: PMC1497529.
    292. Dalton JP, Brindley PJ, Knox DP, Brady CP, Hotez PJ, Donnelly S, O'Neill SM, Mulcahy G, Loukas A. Helminth vaccines: from mining genomic information for vaccine targets to systems used for protein expression. Int J Parasitol. 2003 May; 33(5-6):621-40. PMID: 12782060.
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    293. Jian X, Sen L, Hui-Qin Q, Hai-Nan R, Tie-Hua L, Hai-Chou X, Hotez PJ, Shu-Hua X. Necator americanus: maintenance through one hundred generations in golden hamsters (Mesocricetus auratus). I. Host sex-associated differences in hookworm burden and fecundity. Exp Parasitol. 2003 May-Jun; 104(1-2):62-6. PMID: 12932761.
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    294. Williamson AL, Brindley PJ, Abbenante G, Datu BJ, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Zhan B, Loukas A. Hookworm aspartic protease, Na-APR-2, cleaves human hemoglobin and serum proteins in a host-specific fashion. J Infect Dis. 2003 Feb 1; 187(3):484-94. PMID: 12552433.
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    295. Zhu XP, Yang J, Yang YP, Boireau P, Zhan B, Feng JJ, Hotez P. [Prokaryotic expression and characterization of an antigenic gene of adult Trichinella spiralis]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2003; 21(1):16-9. PMID: 12884582.
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    296. Basavaraju SV, Basavaraju S, Zhan B, Kennedy MW, Liu Y, Hawdon J, Hotez PJ. Ac-FAR-1, a 20 kDa fatty acid- and retinol-binding protein secreted by adult Ancylostoma caninum hookworms: gene transcription pattern, ligand binding properties and structural characterisation. Mol Biochem Parasitol. 2003 Jan; 126(1):63-71. PMID: 12554085.
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    297. Hotez PJ. Loss of laboratory instruction in American medical schools: erosion of Flexner's view of "scientific medical education.". Am J Med Sci. 2003 Jan; 325(1):10-4. PMID: 12544079.
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    298. Bethony J, Chen J, Lin S, Xiao S, Zhan B, Li S, Xue H, Xing F, Humphries D, Yan W, Chen G, Foster V, Hawdon JM, Hotez PJ. Emerging patterns of hookworm infection: influence of aging on the intensity of Necator infection in Hainan Province, People's Republic of China. Clin Infect Dis. 2002 Dec 1; 35(11):1336-44. PMID: 12439796.
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    299. Broder S, Hoffman SL, Hotez PJ. Cures for the Third World's problems: the application of genomics to the diseases plaguing the developing world may have huge medical and economic benefits for those countries and might even prevent armed conflict. EMBO Rep. 2002 Sep; 3(9):806-12. PMID: 12223456; PMCID: PMC1084240.
    300. Hotez PJ, Ashcom J, Bin Z, Bethony J, Williamson A, Hawdon JM, Jianjun F, Dobardzic A, Rizo I, Bolden J, Jin Q, Yan W, Dobardzic R, Chung-Debose S, Crowell M, Datu B, Delaney A, Dragonovski D, Jiang Y, Yueyuan L, Ghosh K, Loukas A, Brandt W, Russell PK, Zook BC. Effect of vaccinations with recombinant fusion proteins on Ancylostoma caninum habitat selection in the canine intestine. J Parasitol. 2002 Aug; 88(4):684-90. PMID: 12197114.
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    301. Mingjie W, Shuhua X, Junjie C, Bin L, Cheng F, Weixia S, Hotez P. Albendazole-soybean oil emulsion for the treatment of human cystic echinococcosis: evaluation of bioavailability and bioequivalence. Acta Trop. 2002 Aug; 83(2):177-81. PMID: 12088859.
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    302. Williamson AL, Brindley PJ, Abbenante G, Prociv P, Berry C, Girdwood K, Pritchard DI, Fairlie DP, Hotez PJ, Dalton JP, Loukas A. Cleavage of hemoglobin by hookworm cathepsin D aspartic proteases and its potential contribution to host specificity. FASEB J. 2002 Sep; 16(11):1458-60. PMID: 12205047.
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    303. Zhan B, Hotez PJ, Wang Y, Hawdon JM. A developmentally regulated metalloprotease secreted by host-stimulated Ancylostoma caninum third-stage infective larvae is a member of the astacin family of proteases. Mol Biochem Parasitol. 2002 Apr 9; 120(2):291-6. PMID: 11897134.
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    304. Shuhua X, Jiqing Y, Mingjie W, Pieying J, Fanghua G, Junjie C, Wei J, Hotez P. Augmented bioavailability and cysticidal activity of albendazole reformulated in soybean emulsion in mice infected with Echinococcus granulosus or Echinococcus multilocularis. Acta Trop. 2002 Apr; 82(1):77-84. PMID: 11904106.
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    305. Zhan B, Badamchian M, Meihua B, Ashcom J, Feng J, Hawdon J, Shuhua X, Hotez PJ. Molecular cloning and purification of Ac-TMP, a developmentally regulated putative tissue inhibitor of metalloprotease released in relative abundance by adult Ancylostoma hookworms. Am J Trop Med Hyg. 2002 Mar; 66(3):238-44. PMID: 12139214.
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    306. Jones BF, Hotez PJ. Molecular cloning and characterization of Ac-mep-1, a developmentally regulated gut luminal metalloendopeptidase from adult Ancylostoma caninum hookworms. Mol Biochem Parasitol. 2002 Jan; 119(1):107-16. PMID: 11755191.
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    307. Shuhua X, Hotez PJ, Binggui S, Sen L, Huiqing Q, Haichou X, Bin Z, Zheng F. Electron and light microscopy of neutrophil responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Parasitol Int. 2001 Nov; 50(4):241-8. PMID: 11719110.
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    308. Hotez PJ. Vaccines as instruments of foreign policy. The new vaccines for tropical infectious diseases may have unanticipated uses beyond fighting diseases. EMBO Rep. 2001 Oct; 2(10):862-8. PMID: 11600443; PMCID: PMC1084093.
    309. Gandhi NS, Jizhang C, Khoshnood K, Fuying X, Shanwen L, Yaoruo L, Bin Z, Haechou X, Chongjin T, Yan W, Wensen W, Dungxing H, Chong C, Shuhua X, Hawdon JM, Hotez PJ. Epidemiology of Necator americanus hookworm infections in Xiulongkan Village, Hainan Province, China: high prevalence and intensity among middle-aged and elderly residents. J Parasitol. 2001 Aug; 87(4):739-43. PMID: 11534635.
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    310. Sharghi N, Schantz PM, Caramico L, Ballas K, Teague BA, Hotez PJ. Environmental exposure to Toxocara as a possible risk factor for asthma: a clinic-based case-control study. Clin Infect Dis. 2001 Apr 1; 32(7):E111-6. PMID: 11264048.
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    311. Wen LY, Hotez PJ. [Studies on immunological reaction of the antiserum of recombinant secreted protein from Ancylostoma caninum]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2001; 19(3):166-8. PMID: 12571945.
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    312. Shuhua X, Hotez PJ, Tanner M. Artemether, an effective new agent for chemoprophylaxis against shistosomiasis in China: its in vivo effect on the biochemical metabolism of the Asian schistosome. Southeast Asian J Trop Med Public Health. 2000 Dec; 31(4):724-32. PMID: 11414420.
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    313. Haichou X, Yan W, Shuhua X, Sen L, Yong W, Guangjin S, Weituo W, Bin Z, Drake L, Zheng F, Hotez PJ. Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou Village), Anhui Province, China: II. Seroepidemiological studies of the age relationships of serum antibody levels and infection status. Southeast Asian J Trop Med Public Health. 2000 Dec; 31(4):736-41. PMID: 11414422.
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    314. Lili Z, Bingxiang Z, Hong T, Shuhua X, Hotez P, Bing Z, Yangzhong L, Ying L, Haichou X, Hawdon J, Hui Y, Huizhen W, Zhen F. Epidemiology of human geohelminth infections (ascariasis, trichuriasis and necatoriasis) in Lushui and Puer Counties, Yunnan Province, China. Southeast Asian J Trop Med Public Health. 2000 Sep; 31(3):448-53. PMID: 11288999.
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    315. Cowden J, Hotez P. Mebendazole and albendazole treatment of geohelminth infections in children and pregnant women. Pediatr Infect Dis J. 2000 Jul; 19(7):659-60. PMID: 10917227.
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    316. Qiang S, Bin Z, Shu-hua X, Zheng F, Hotez P, Hawdon JM. Variation between ASP-1 molecules from Ancylostoma caninum in China and the United States. J Parasitol. 2000 Feb; 86(1):181-5. PMID: 10701589.
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    317. Sen L, Ghosh K, Bin Z, Qiang S, Thompson MG, Hawdon JM, Koski RA, Shuhua X, Hotez PJ. Hookworm burden reductions in BALB/c mice vaccinated with recombinant Ancylostoma secreted proteins (ASPs) from Ancylostoma duodenale, Ancylostoma caninum and Necator americanus. Vaccine. 2000 Jan 6; 18(11-12):1096-102. PMID: 10590331.
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    318. Tissenbaum HA, Hawdon J, Perregaux M, Hotez P, Guarente L, Ruvkun G. A common muscarinic pathway for diapause recovery in the distantly related nematode species Caenorhabditis elegans and Ancylostoma caninum. Proc Natl Acad Sci U S A. 2000 Jan 4; 97(1):460-5. PMID: 10618440; PMCID: PMC26685.
    319. Zhan B, Hawdon J, Shan Q, Ren H, Qiang H, Xiao SH, Li TH, Feng Z, Hotez P. Construction and analysis of cDNA library of Necator americanus third stage larvae. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 2000; 18(1):26-8. PMID: 12567467.
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    320. Xiao S, Ren H, Yang Y, Liu S, Qiang H, Xue H, Feng Z, Hotez PJ. Length of protection by murine vaccination with living infective third-stage hookworm larvae. Chin Med J (Engl). 1999 Dec; 112(12):1129-32. PMID: 11721454.
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    321. Hotez PJ. Acceptance of the 1999 Henry Baldwin Ward Medal. J Parasitol. 1999 Dec; 85(6):1001-5. PMID: 10647029.
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    322. Yong W, Guangjin S, Weitu W, Shuhua X, Hotez PJ, Qiyang L, Haichou X, Xiaomei Y, Xiaoming L, Bin Z, Hawdon JM, Li C, Hong J, Chunmei H, Zheng F. Epidemiology of human ancylostomiasis among rural villagers in Nanlin County (Zhongzhou village), Anhui Province, China: age-associated prevalence, intensity and hookworm species identification. Southeast Asian J Trop Med Public Health. 1999 Dec; 30(4):692-7. PMID: 10928362.
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    323. Yang Y, Xiao S, Ren H, Wu J, Feng Z, Hotez PJ. Cutaneous and subcutaneous mast cell and eosinophil responses after challenge in mice vaccinated with living infective third-stage hookworm larvae. Chin Med J (Engl). 1999 Nov; 112(11):1020-3. PMID: 11721464.
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    324. Ghosh K, Hotez PJ. Antibody-dependent reductions in mouse hookworm burden after vaccination with Ancylostoma caninum secreted protein 1. J Infect Dis. 1999 Nov; 180(5):1674-81. PMID: 10515831.
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    325. Changhua L, Xiaorong Z, Dongchuan Q, Shuhua X, Hotez PJ, Defu Z, Hulian Z, Mingden L, Hainan R, Bing Z, Haichou X, Hawdon J, Zheng F. Epidemiology of human hookworm infections among adult villagers in Hejiang and Santai Counties, Sichuan Province, China. Acta Trop. 1999 Oct 15; 73(3):243-9. PMID: 10546842.
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    326. Hotez PJ, Ghosh K, Hawdon JM, Narasimhan S, Jones B, Shuhua X, Sen L, Bin Z, Haechou X, Hainan R, Heng W, Koski RA. Experimental approaches to the development of a recombinant hookworm vaccine. Immunol Rev. 1999 Oct; 171:163-71. PMID: 10582170.
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    327. Labiano-Abello N, Canese J, Velazquez ME, Hawdon JM, Wilson ML, Hotez PJ. Epidemiology of hookworm infection in Itagua, Paraguay: a cross sectional study. Mem Inst Oswaldo Cruz. 1999 Sep-Oct; 94(5):583-6. PMID: 10464397.
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    328. Yuanqing Y, Shuhua X, Hotez PJ, Jiadong W. Histochemical alterations of infective third-stage hookworm larvae (L3) in vaccinated mice. Southeast Asian J Trop Med Public Health. 1999 Jun; 30(2):356-64. PMID: 10774709.
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    329. Hawdon JM, Narasimhan S, Hotez PJ. Ancylostoma secreted protein 2: cloning and characterization of a second member of a family of nematode secreted proteins from Ancylostoma caninum. Mol Biochem Parasitol. 1999 Apr 30; 99(2):149-65. PMID: 10340481.
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    330. Xue H, Liu S, Ren H, Qiang H, Xiao S, Feng Z, Hotez P. Enzyme-linked immunoelectrotransfer blotting analysis of human serologic responses to infective hookworm larval antigen. Chin Med J (Engl). 1999 Mar; 112(3):249-50. PMID: 11593560.
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    331. Bin Z, Hawdon J, Qiang S, Hainan R, Huiqing Q, Wei H, Shu-Hua X, Tiehua L, Xing G, Zheng F, Hotez P. Ancylostoma secreted protein 1 (ASP-1) homologues in human hookworms. Mol Biochem Parasitol. 1999 Jan 5; 98(1):143-9. PMID: 10029316.
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    332. Li T, Zhan B, Hawdon JM, Gong X, Xiao S, Shan Q, Feng Z, Hotez PJ. [Sequencing of cytochrome C oxidase 1 gene of Ancylostoma duodenale and Necator americanus]. Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi. 1999; 17(2):81-3. PMID: 12563786.
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    333. Shuhua X, Hotez PJ, Binggui S, Sen L, Hainan R, Haichou X, Huiqing Q, Zheng F. Electron and light microscopy of peritoneal cellular immune responses in mice vaccinated and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Trop. 1998 Sep 15; 71(2):155-67. PMID: 9821464.
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    334. Fenghua S, Zhongxing W, Yixing Q, Hangqun C, Haichou X, Hainan R, Shuhua X, Bin Z, Hawdon JM, Zheng F, Hotez PJ. Epidemiology of human intestinal nematode infections in Wujiang and Pizhou counties, Jiangsu Province, China. Southeast Asian J Trop Med Public Health. 1998 Sep; 29(3):605-10. PMID: 10437966.
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    335. Pao W, Duncan KO, Bolognia JL, Carroll CB, Hotez PJ, Bessen DE. Numerous eruptive lesions of panniculitis associated with group A streptococcus bacteremia in an immunocompetent child. Clin Infect Dis. 1998 Sep; 27(3):430-3. PMID: 9770136.
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    336. Yang Y, Xiau S, Ren H, Wu J, Hotez PJ. Cutaneous and subcutaneous granulomata formation in mice immunized and challenged with third-stage infective hookworm (Ancylostoma caninum) larvae. Acta Trop. 1998 Jun; 69(3):229-38. PMID: 9638275.
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    337. Shuxian L, Guangchen S, Yuxin X, McManus DP, Hotez PJ. Progress in the development of a vaccine against schistosomiasis in China. Int J Infect Dis. 1998 Jan-Mar; 2(3):176-80. PMID: 9625614.
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    338. Xiao S, Ren H, Yang Y, Xue H, Qiang H, Liu S, Feng Z, Hotez PJ. Protective immunity in mice elicited by living infective third-stage hookworm larvae (Shanghai strain of Ancylostoma caninum). Chin Med J (Engl). 1998 Jan; 111(1):43-8. PMID: 10322652.
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    339. Hotez PJ, Ghosh K, Hawdon J, Narasimhan S, Jones B, Bethony J. Vaccines for hookworm infection. Pediatr Infect Dis J. 1997 Oct; 16(10):935-40. PMID: 9380467.
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    340. Hotez PJ, Zheng F, Long-qi X, Ming-gang C, Shu-hua X, Shu-xian L, Blair D, McManus DP, Davis GM. Emerging and reemerging helminthiases and the public health of China. Emerg Infect Dis. 1997 Jul-Sep; 3(3):303-10. PMID: 9284374; PMCID: PMC2627641.
    341. Ghosh K, Hawdon J, Hotez P. Vaccination with alum-precipitated recombinant Ancylostoma-secreted protein 1 protects mice against challenge infections with infective hookworm (Ancylostoma caninum) larvae. J Infect Dis. 1996 Dec; 174(6):1380-3. PMID: 8940240.
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    342. Hotez PJ, Hawdon JM, Cappello M, Jones BF, Ghosh K, Volvovitz F, Xiao SH. Molecular approaches to vaccinating against hookworm disease. Pediatr Res. 1996 Oct; 40(4):515-21. PMID: 8888276.
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    343. Hawdon JM, Hotez PJ. Hookworm: developmental biology of the infectious process. Curr Opin Genet Dev. 1996 Oct; 6(5):618-23. PMID: 8939719.
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    344. Cappello M, Hawdon JM, Jones BF, Kennedy WP, Hotez PJ. Ancylostoma caninum anticoagulant peptide: cloning by PCR and expression of soluble, active protein in E. coli. Mol Biochem Parasitol. 1996 Sep; 80(1):113-7. PMID: 8885227.
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    345. Hawdon JM, Jones BF, Hoffman DR, Hotez PJ. Cloning and characterization of Ancylostoma-secreted protein. A novel protein associated with the transition to parasitism by infective hookworm larvae. J Biol Chem. 1996 Mar 22; 271(12):6672-8. PMID: 8636085.
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    346. Stassens P, Bergum PW, Gansemans Y, Jespers L, Laroche Y, Huang S, Maki S, Messens J, Lauwereys M, Cappello M, Hotez PJ, Lasters I, Vlasuk GP. Anticoagulant repertoire of the hookworm Ancylostoma caninum. Proc Natl Acad Sci U S A. 1996 Mar 5; 93(5):2149-54. PMID: 8700900; PMCID: PMC39925.
    347. Cappello M, Vlasuk GP, Bergum PW, Huang S, Hotez PJ. Ancylostoma caninum anticoagulant peptide: a hookworm-derived inhibitor of human coagulation factor Xa. Proc Natl Acad Sci U S A. 1995 Jun 20; 92(13):6152-6. PMID: 7597095; PMCID: PMC41660.
    348. Hotez PJ, Hawdon JM, Cappello M, Jones BF, Pritchard DI. Molecular pathobiology of hookworm infection. Infect Agents Dis. 1995 Jun; 4(2):71-5. PMID: 7613730.
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    349. Hawdon JM, Jones BF, Perregaux MA, Hotez PJ. Ancylostoma caninum: metalloprotease release coincides with activation of infective larvae in vitro. Exp Parasitol. 1995 Mar; 80(2):205-11. PMID: 7895832.
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    350. Hawdon JM, Jones BF, Hotez PJ. Cloning and characterization of a cDNA encoding the catalytic subunit of a cAMP-dependent protein kinase from Ancylostoma caninum third-stage infective larvae. Mol Biochem Parasitol. 1995 Jan; 69(1):127-30. PMID: 7723782.
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    351. Hotez P, Cappello M, Hawdon J, Beckers C, Sakanari J. Hyaluronidases of the gastrointestinal invasive nematodes Ancylostoma caninum and Anisakis simplex: possible functions in the pathogenesis of human zoonoses. J Infect Dis. 1994 Oct; 170(4):918-26. PMID: 7930737.
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    352. Cappello M, Clyne LP, McPhedran P, Hotez PJ. Ancylostoma factor Xa inhibitor: partial purification and its identification as a major hookworm-derived anticoagulant in vitro. J Infect Dis. 1993 Jun; 167(6):1474-7. PMID: 8501344.
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    353. Hotez P, Hawdon J, Schad GA. Hookworm larval infectivity, arrest and amphiparatenesis: the Caenorhabditis elegans Daf-c paradigm. Parasitol Today. 1993 Jan; 9(1):23-6. PMID: 15463660.
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    354. Hotez PJ, Narasimhan S, Haggerty J, Milstone L, Bhopale V, Schad GA, Richards FF. Hyaluronidase from infective Ancylostoma hookworm larvae and its possible function as a virulence factor in tissue invasion and in cutaneous larva migrans. Infect Immun. 1992 Mar; 60(3):1018-23. PMID: 1541516; PMCID: PMC257588.
    355. Hotez P, Haggerty J, Hawdon J, Milstone L, Gamble HR, Schad G, Richards F. Metalloproteases of infective Ancylostoma hookworm larvae and their possible functions in tissue invasion and ecdysis. Infect Immun. 1990 Dec; 58(12):3883-92. PMID: 2254016; PMCID: PMC313750.
    356. Hotez PJ, Le Trang N, Cerami A. Hookworm antigens: the potential for vaccination. Parasitol Today. 1987 Aug; 3(8):247-9. PMID: 15462967.
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    357. Hotez PJ, Trang NL, McKerrow JH, Cerami A. Isolation and characterization of a proteolytic enzyme from the adult hookworm Ancylostoma caninum. J Biol Chem. 1985 Jun 25; 260(12):7343-8. PMID: 3888998.
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    358. Hotez PJ, Le Trang N, Fairlamb AH, Cerami A. Lipoprotein lipase suppression in 3T3-L1 cells by a haematoprotozoan-induced mediator from peritoneal exudate cells. Parasite Immunol. 1984 May; 6(3):203-9. PMID: 6377200.
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    359. Richards FF, Rosen NL, Onodera M, Bogucki MS, Neve RL, Hotez P, Armstrong MY, Konigsberg WH. Antigenic variation and the surface glycoproteins of Trypanosoma congolense. Fed Proc. 1981 Apr; 40(5):1434-9. PMID: 6163660.
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