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DAVID A NIELSEN

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Psychiatry & Behavioral Sciences
AddressONE BAYLOR PLAZA
HOUSTON TX 77030
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Pharmacology
    DivisionPharmacology

    TitleAssociate Professor
    InstitutionBaylor College of Medicine


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Shorter D, Nielsen DA, Hamon SC, Nielsen EM, Kosten TR, Newton TF, De La Garza R. The ?-1 adrenoceptor (ADRA1A) genotype moderates the magnitude of acute cocaine-induced subjective effects in cocaine-dependent individuals. Pharmacogenet Genomics. 2016 Sep; 26(9):428-35. PMID: 27379509; PMCID: PMC4970930 [Available on 09/01/17].
    2. Nieto SJ, Patriquin MA, Nielsen DA, Kosten TA. Don't worry; be informed about the epigenetics of anxiety. Pharmacol Biochem Behav. 2016 Jul-Aug; 146-147:60-72. PMID: 27189589; PMCID: PMC4939112 [Available on 07/01/17].
    3. Cao B, Bauer IE, Sharma AN, Mwangi B, Frazier T, Lavagnino L, Zunta-Soares GB, Walss-Bass C, Glahn DC, Kapczinski F, Nielsen DA, Soares JC. Reduced hippocampus volume and memory performance in bipolar disorder patients carrying the BDNF val66met met allele. J Affect Disord. 2016 Jul 1; 198:198-205. PMID: 27018938.
      View in: PubMed
    4. Sharp C, Fowler JC, Salas R, Nielsen D, Allen J, Oldham J, Kosten T, Mathew S, Madan A, Frueh BC, Fonagy P. Operationalizing NIMH Research Domain Criteria (RDoC) in naturalistic clinical settings. Bull Menninger Clin. 2016; 80(3):187-212. PMID: 27583809.
      View in: PubMed
    5. Azadeh S, Hobbs BP, Ma L, Nielsen DA, Moeller FG, Baladandayuthapani V. Integrative Bayesian analysis of neuroimaging-genetic data with application to cocaine dependence. Neuroimage. 2016 Jan 15; 125:813-24. PMID: 26484829.
      View in: PubMed
    6. Patriquin MA, Bauer IE, Soares JC, Graham DP, Nielsen DA. Addiction pharmacogenetics: a systematic review of the genetic variation of the dopaminergic system. Psychiatr Genet. 2015 Oct; 25(5):181-93. PMID: 26146874.
      View in: PubMed
    7. Bauer IE, Graham DP, Soares JC, Nielsen DA. Serotonergic gene variation in substance use pharmacotherapy: a systematic review. Pharmacogenomics. 2015; 16(11):1307-14. PMID: 26265436.
      View in: PubMed
    8. Wachman EM, Hayes MJ, Sherva R, Brown MS, Davis JM, Farrer LA, Nielsen DA. Variations in opioid receptor genes in neonatal abstinence syndrome. Drug Alcohol Depend. 2015 Oct 1; 155:253-9. PMID: 26233486.
      View in: PubMed
    9. Brewer AJ, Nielsen DA, Spellicy CJ, Hamon SC, Gingrich J, Thompson-Lake DG, Nielsen EM, Mahoney JJ, Kosten TR, Newton TF, De La Garza R. Genetic variation of the dopamine transporter (DAT1) influences the acute subjective responses to cocaine in volunteers with cocaine use disorders. Pharmacogenet Genomics. 2015 Jun; 25(6):296-304. PMID: 25850966; PMCID: PMC4414865.
    10. Bauer IE, Soares JC, Nielsen DA. The role of opioidergic genes in the treatment outcome of drug addiction pharmacotherapy: A systematic review. Am J Addict. 2015 Jan; 24(1):15-23. PMID: 25823631.
      View in: PubMed
    11. Graham DP, Nielsen DA, Kosten TR, Davis LL, Hamner MB, Makotkine I, Yehuda R. Examining the utility of using genotype and functional biology in a clinical pharmacology trial: pilot testing dopamine ?-hydroxylase, norepinephrine, and post-traumatic stress disorder. Psychiatr Genet. 2014 Aug; 24(4):181-2. PMID: 24983834; PMCID: PMC4080201.
    12. Liu S, Green CE, Lane SD, Kosten TR, Moeller FG, Nielsen DA, Schmitz JM. The influence of dopamine ?-hydroxylase gene polymorphism rs1611115 on levodopa/carbidopa treatment for cocaine dependence: a preliminary study. Pharmacogenet Genomics. 2014 Jul; 24(7):370-3. PMID: 24809448.
      View in: PubMed
    13. Wachman EM, Hayes MJ, Lester BM, Terrin N, Brown MS, Nielsen DA, Davis JM. Epigenetic variation in the mu-opioid receptor gene in infants with neonatal abstinence syndrome. J Pediatr. 2014 Sep; 165(3):472-8. PMID: 24996986; PMCID: PMC4145036.
    14. Kosten TA, Nielsen DA. Litter and sex effects on maternal behavior and DNA methylation of the Nr3c1 exon 17 promoter gene in hippocampus and cerebellum. Int J Dev Neurosci. 2014 Aug; 36:5-12. PMID: 24721039; PMCID: PMC4101021.
    15. Frazier TW, Youngstrom EA, Frankel BA, Zunta-Soares GB, Sanches M, Escamilla M, Nielsen DA, Soares JC. Candidate gene associations with mood disorder, cognitive vulnerability, and fronto-limbic volumes. Brain Behav. 2014 May; 4(3):418-30. PMID: 24944871; PMCID: PMC4055192.
    16. Spellicy CJ, Harding MJ, Hamon SC, Mahoney JJ, Reyes JA, Kosten TR, Newton TF, De La Garza R, Nielsen DA. A variant in ANKK1 modulates acute subjective effects of cocaine: a preliminary study. Genes Brain Behav. 2014 Jul; 13(6):559-64. PMID: 24528631; PMCID: PMC4079840.
    17. Anastasio NC, Liu S, Maili L, Swinford SE, Lane SD, Fox RG, Hamon SC, Nielsen DA, Cunningham KA, Moeller FG. Variation within the serotonin (5-HT) 5-HT?C receptor system aligns with vulnerability to cocaine cue reactivity. Transl Psychiatry. 2014; 4:e369. PMID: 24618688; PMCID: PMC3966037.
    18. Nielsen DA, Nielsen EM, Dasari T, Spellicy CJ. Pharmacogenetics of addiction therapy. Methods Mol Biol. 2014; 1175:589-624. PMID: 25150877.
      View in: PubMed
    19. Nielsen DA, Hamon SC, Kosten TR. The ?-opioid receptor gene as a predictor of response in a cocaine vaccine clinical trial. Psychiatr Genet. 2013 Dec; 23(6):225-32. PMID: 23995774; PMCID: PMC3885873.
    20. Shorter D, Nielsen DA, Huang W, Harding MJ, Hamon SC, Kosten TR. Pharmacogenetic randomized trial for cocaine abuse: disulfiram and ?1A-adrenoceptor gene variation. Eur Neuropsychopharmacol. 2013 Nov; 23(11):1401-7. PMID: 23849431; PMCID: PMC3818518.
    21. Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA. ANKK1 and DRD2 pharmacogenetics of disulfiram treatment for cocaine abuse. Pharmacogenet Genomics. 2013 Jul; 23(7):333-40. PMID: 23635803.
      View in: PubMed
    22. Graham DP, Helmer DA, Harding MJ, Kosten TR, Petersen NJ, Nielsen DA. Serotonin transporter genotype and mild traumatic brain injury independently influence resilience and perception of limitations in veterans. J Psychiatr Res. 2013 Jun; 47(6):835-42. PMID: 23478049; PMCID: PMC3643301.
    23. Kosten TA, Huang W, Nielsen DA. Sex and litter effects on anxiety and DNA methylation levels of stress and neurotrophin genes in adolescent rats. Dev Psychobiol. 2014 Apr; 56(3):392-406. PMID: 23460384.
      View in: PubMed
    24. Kosten TR, Domingo CB, Hamon SC, Nielsen DA. DBH gene as predictor of response in a cocaine vaccine clinical trial. Neurosci Lett. 2013 Apr 29; 541:29-33. PMID: 23458673; PMCID: PMC3631430.
    25. Spellicy CJ, Kosten TR, Hamon SC, Harding MJ, Nielsen DA. The MTHFR C677T Variant is Associated with Responsiveness to Disulfiram Treatment for Cocaine Dependency. Front Psychiatry. 2012; 3:109. PMID: 23335901; PMCID: PMC3544007.
    26. Haile CN, De La Garza R, Mahoney JJ, Nielsen DA, Kosten TR, Newton TF. The impact of disulfiram treatment on the reinforcing effects of cocaine: a randomized clinical trial. PLoS One. 2012; 7(11):e47702. PMID: 23144826; PMCID: PMC3493584.
    27. Nielsen DA, Harding MJ, Hamon SC, Huang W, Kosten TR. Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study. Genes Brain Behav. 2012 Nov; 11(8):1001-8. PMID: 22925276.
      View in: PubMed
    28. Kosten TR, Wu G, Huang W, Harding MJ, Hamon SC, Lappalainen J, Nielsen DA. Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine ?-hydroxylase. Biol Psychiatry. 2013 Feb 1; 73(3):219-24. PMID: 22906516; PMCID: PMC3514624.
    29. Nielsen DA, Utrankar A, Reyes JA, Simons DD, Kosten TR. Epigenetics of drug abuse: predisposition or response. Pharmacogenomics. 2012 Jul; 13(10):1149-60. PMID: 22909205; PMCID: PMC3463407.
    30. Nielsen DA, Huang W, Hamon SC, Maili L, Witkin BM, Fox RG, Cunningham KA, Moeller FG. Forced Abstinence from Cocaine Self-Administration is Associated with DNA Methylation Changes in Myelin Genes in the Corpus Callosum: a Preliminary Study. Front Psychiatry. 2012; 3:60. PMID: 22712019; PMCID: PMC3374938.
    31. Nielsen DA, Kreek MJ. Common and specific liability to addiction: approaches to association studies of opioid addiction. Drug Alcohol Depend. 2012 Jun; 123 Suppl 1:S33-41. PMID: 22542464; PMCID: PMC3689423.
    32. Nielsen DA, Ho A, Bahl A, Varma P, Kellogg S, Borg L, Kreek MJ. Former heroin addicts with or without a history of cocaine dependence are more impulsive than controls. Drug Alcohol Depend. 2012 Jul 1; 124(1-2):113-20. PMID: 22265192; PMCID: PMC3372650.
    33. Hao Y, Huang W, Nielsen DA, Kosten TA. Litter gender composition and sex affect maternal behavior and DNA methylation levels of the oprm1 gene in rat offspring. Front Psychiatry. 2011; 2:21. PMID: 21629839; PMCID: PMC3098712.
    34. Yuferov V, Nielsen DA, Levran O, Randesi M, Hamon S, Ho A, Morgello S, Kreek MJ. Tissue-specific DNA methylation of the human prodynorphin gene in post-mortem brain tissues and PBMCs. Pharmacogenet Genomics. 2011 Apr; 21(4):185-96. PMID: 20808262; PMCID: PMC3017726.
    35. Nielsen DA, Ji F, Yuferov V, Ho A, He C, Ott J, Kreek MJ. Genome-wide association study identifies genes that may contribute to risk for developing heroin addiction. Psychiatr Genet. 2010 Oct; 20(5):207-14. PMID: 20520587; PMCID: PMC3832188.
    36. Rouault M, Nielsen DA, Ho A, Kreek MJ, Yuferov V. Cell-specific effects of variants of the 68-base pair tandem repeat on prodynorphin gene promoter activity. Addict Biol. 2011 Apr; 16(2):334-46. PMID: 20731629; PMCID: PMC2995810.
    37. Briant JA, Nielsen DA, Proudnikov D, Londono D, Ho A, Ott J, Kreek MJ. Evidence for association of two variants of the nociceptin/orphanin FQ receptor gene OPRL1 with vulnerability to develop opiate addiction in Caucasians. Psychiatr Genet. 2010 Apr; 20(2):65-72. PMID: 20032820; PMCID: PMC3832186.
    38. Nielsen DA, Hamon S, Yuferov V, Jackson C, Ho A, Ott J, Kreek MJ. Ethnic diversity of DNA methylation in the OPRM1 promoter region in lymphocytes of heroin addicts. Hum Genet. 2010 Jun; 127(6):639-49. PMID: 20237803; PMCID: PMC3739429.
    39. Yuferov V, Levran O, Proudnikov D, Nielsen DA, Kreek MJ. Search for genetic markers and functional variants involved in the development of opiate and cocaine addiction and treatment. Ann N Y Acad Sci. 2010 Feb; 1187:184-207. PMID: 20201854; PMCID: PMC3769182.
    40. Yuferov V, Ji F, Nielsen DA, Levran O, Ho A, Morgello S, Shi R, Ott J, Kreek MJ. A functional haplotype implicated in vulnerability to develop cocaine dependence is associated with reduced PDYN expression in human brain. Neuropsychopharmacology. 2009 Apr; 34(5):1185-97. PMID: 18923396; PMCID: PMC2778041.
    41. Oosterhuis BE, LaForge KS, Proudnikov D, Ho A, Nielsen DA, Gianotti R, Barral S, Gordon D, Leal SM, Ott J, Kreek MJ. Catechol-O-methyltransferase (COMT) gene variants: possible association of the Val158Met variant with opiate addiction in Hispanic women. Am J Med Genet B Neuropsychiatr Genet. 2008 Sep 5; 147B(6):793-8. PMID: 18270997; PMCID: PMC2909109.
    42. Kreek MJ, Schlussman SD, Reed B, Zhang Y, Nielsen DA, Levran O, Zhou Y, Butelman ER. Bidirectional translational research: Progress in understanding addictive diseases. Neuropharmacology. 2009; 56 Suppl 1:32-43. PMID: 18725235; PMCID: PMC2741728.
    43. Nielsen DA, Yuferov V, Hamon S, Jackson C, Ho A, Ott J, Kreek MJ. Increased OPRM1 DNA methylation in lymphocytes of methadone-maintained former heroin addicts. Neuropsychopharmacology. 2009 Mar; 34(4):867-73. PMID: 18650805; PMCID: PMC2778040.
    44. Levran O, Londono D, O'Hara K, Nielsen DA, Peles E, Rotrosen J, Casadonte P, Linzy S, Randesi M, Ott J, Adelson M, Kreek MJ. Genetic susceptibility to heroin addiction: a candidate gene association study. Genes Brain Behav. 2008 Oct; 7(7):720-9. PMID: 18518925; PMCID: PMC2885890.
    45. Nielsen DA, Ji F, Yuferov V, Ho A, Chen A, Levran O, Ott J, Kreek MJ. Genotype patterns that contribute to increased risk for or protection from developing heroin addiction. Mol Psychiatry. 2008 Apr; 13(4):417-28. PMID: 18195715; PMCID: PMC3810149.
    46. Nielsen DA, Barral S, Proudnikov D, Kellogg S, Ho A, Ott J, Kreek MJ. TPH2 and TPH1: association of variants and interactions with heroin addiction. Behav Genet. 2008 Mar; 38(2):133-50. PMID: 18181017.
      View in: PubMed
    47. Kroslak T, Laforge KS, Gianotti RJ, Ho A, Nielsen DA, Kreek MJ. The single nucleotide polymorphism A118G alters functional properties of the human mu opioid receptor. J Neurochem. 2007 Oct; 103(1):77-87. PMID: 17877633.
      View in: PubMed
    48. Nielsen DA, Leidner M, Haynes C, Krauthammer M, Kreek MJ. The BiolAD-DB system : an informatics system for clinical and genetic data. Mol Diagn Ther. 2007; 11(1):15-9. PMID: 17286447.
      View in: PubMed
    49. Kreek MJ, Nielsen DA, Butelman ER, LaForge KS. Genetic influences on impulsivity, risk taking, stress responsivity and vulnerability to drug abuse and addiction. Nat Neurosci. 2005 Nov; 8(11):1450-7. PMID: 16251987.
      View in: PubMed
    50. Yuferov V, Nielsen D, Butelman E, Kreek MJ. Microarray studies of psychostimulant-induced changes in gene expression. Addict Biol. 2005 Mar; 10(1):101-18. PMID: 15849024.
      View in: PubMed
    51. Kreek MJ, Bart G, Lilly C, LaForge KS, Nielsen DA. Pharmacogenetics and human molecular genetics of opiate and cocaine addictions and their treatments. Pharmacol Rev. 2005 Mar; 57(1):1-26. PMID: 15734726.
      View in: PubMed
    52. Yuferov V, Fussell D, LaForge KS, Nielsen DA, Gordon D, Ho A, Leal SM, Ott J, Kreek MJ. Redefinition of the human kappa opioid receptor gene (OPRK1) structure and association of haplotypes with opiate addiction. Pharmacogenetics. 2004 Dec; 14(12):793-804. PMID: 15608558.
      View in: PubMed
    53. Kreek MJ, Nielsen DA, LaForge KS. Genes associated with addiction: alcoholism, opiate, and cocaine addiction. Neuromolecular Med. 2004; 5(1):85-108. PMID: 15001815.
      View in: PubMed
    54. Roy A, Rylander G, Forslund K, Asberg M, Mazzanti CM, Goldman D, Nielsen DA. Excess tryptophan hydroxylase 17 779C allele in surviving cotwins of monozygotic twin suicide victims. Neuropsychobiology. 2001; 43(4):233-6. PMID: 11340361.
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    55. Nielsen DA, Mazzanti CM, Linnoila M, Goldman D. Serotonin transporter genotype and seasonal variation in serotonin function. Neuropsychopharmacology. 1999 May; 20(5):507-8. PMID: 26468552.
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    56. Han L, Nielsen DA, Rosenthal NE, Jefferson K, Kaye W, Murphy D, Altemus M, Humphries J, Cassano G, Rotondo A, Virkkunen M, Linnoila M, Goldman D. No coding variant of the tryptophan hydroxylase gene detected in seasonal affective disorder, obsessive-compulsive disorder, anorexia nervosa, and alcoholism. Biol Psychiatry. 1999 Mar 1; 45(5):615-9. PMID: 10088048.
      View in: PubMed
    57. Nielsen DA, Virkkunen M, Lappalainen J, Eggert M, Brown GL, Long JC, Goldman D, Linnoila M. A tryptophan hydroxylase gene marker for suicidality and alcoholism. Arch Gen Psychiatry. 1998 Jul; 55(7):593-602. PMID: 9672049.
      View in: PubMed
    58. New AS, Gelernter J, Yovell Y, Trestman RL, Nielsen DA, Silverman J, Mitropoulou V, Siever LJ. Tryptophan hydroxylase genotype is associated with impulsive-aggression measures: a preliminary study. Am J Med Genet. 1998 Feb 7; 81(1):13-7. PMID: 9514581.
      View in: PubMed
    59. Mann JJ, Malone KM, Nielsen DA, Goldman D, Erdos J, Gelernter J. Possible association of a polymorphism of the tryptophan hydroxylase gene with suicidal behavior in depressed patients. Am J Psychiatry. 1997 Oct; 154(10):1451-3. PMID: 9326831.
      View in: PubMed
    60. Rotondo A, Nielsen DA, Nakhai B, Hulihan-Giblin B, Bolos A, Goldman D. Agonist-promoted down-regulation and functional desensitization in two naturally occurring variants of the human serotonin1A receptor. Neuropsychopharmacology. 1997 Jul; 17(1):18-26. PMID: 9194046.
      View in: PubMed
    61. Nielsen DA, Jenkins GL, Stefanisko KM, Jefferson KK, Goldman D. Sequence, splice site and population frequency distribution analyses of the polymorphic human tryptophan hydroxylase intron 7. Brain Res Mol Brain Res. 1997 Apr; 45(1):145-8. PMID: 9105682.
      View in: PubMed
    62. Jönsson EG, Goldman D, Spurlock G, Gustavsson JP, Nielsen DA, Linnoila M, Owen MJ, Sedvall GC. Tryptophan hydroxylase and catechol-O-methyltransferase gene polymorphisms: relationships to monoamine metabolite concentrations in CSF of healthy volunteers. Eur Arch Psychiatry Clin Neurosci. 1997; 247(6):297-302. PMID: 9477008.
      View in: PubMed
    63. Nielsen DA, Goldman D, Virkkunen M, Tokola R, Rawlings R, Linnoila M. TPH replication study: not! Arch Gen Psychiatry. 1996 Oct; 53(10):964-5. PMID: 8857875.
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    64. Henley WN, Schuebel KE, Nielsen DA. Limitations imposed by heteroduplex formation on quantitative RT-PCR. Biochem Biophys Res Commun. 1996 Sep 4; 226(1):113-7. PMID: 8806600.
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    65. Schuebel KE, Bustelo XR, Nielsen DA, Song BJ, Barbacid M, Goldman D, Lee IJ. Isolation and characterization of murine vav2, a member of the vav family of proto-oncogenes. Oncogene. 1996 Jul 18; 13(2):363-71. PMID: 8710375.
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    66. McCarthy MM, Nielsen DA, Goldman D. Antisense oligonucleotide inhibition of tryptophan hydroxylase activity in mouse brain. Regul Pept. 1995 Oct 20; 59(2):163-70. PMID: 8584751.
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    67. Virkkunen M, Goldman D, Nielsen DA, Linnoila M. Low brain serotonin turnover rate (low CSF 5-HIAA) and impulsive violence. J Psychiatry Neurosci. 1995 Jul; 20(4):271-5. PMID: 7544158; PMCID: PMC1188701.
    68. Nielsen DA, Novoradovsky A, Goldman D. SSCP primer design based on single-strand DNA structure predicted by a DNA folding program. Nucleic Acids Res. 1995 Jun 25; 23(12):2287-91. PMID: 7610057; PMCID: PMC307019.
    69. Nakhai B, Nielsen DA, Linnoila M, Goldman D. Two naturally occurring amino acid substitutions in the human 5-HT1A receptor: glycine 22 to serine 22 and isoleucine 28 to valine 28. Biochem Biophys Res Commun. 1995 May 16; 210(2):530-6. PMID: 7755630.
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    70. Linnoila M, Virkkunen M, George T, Eckardt M, Higley JD, Nielsen D, Goldman D. Serotonin, violent behavior and alcohol. EXS. 1994; 71:155-63. PMID: 7518265.
      View in: PubMed
    71. Nielsen DA, Goldman D, Virkkunen M, Tokola R, Rawlings R, Linnoila M. Suicidality and 5-hydroxyindoleacetic acid concentration associated with a tryptophan hydroxylase polymorphism. Arch Gen Psychiatry. 1994 Jan; 51(1):34-8. PMID: 7506517.
      View in: PubMed
    72. Nielsen DA, Dean M, Goldman D. Genetic mapping of the human tryptophan hydroxylase gene on chromosome 11, using an intronic conformational polymorphism. Am J Hum Genet. 1992 Dec; 51(6):1366-71. PMID: 1463016; PMCID: PMC1682899.
    73. Nielsen DA, Shapiro DJ. Insights into hormonal control of messenger RNA stability. Mol Endocrinol. 1990 Jul; 4(7):953-7. PMID: 2284008.
      View in: PubMed
    74. Nielsen DA, Shapiro DJ. Estradiol and estrogen receptor-dependent stabilization of a minivitellogenin mRNA lacking 5,100 nucleotides of coding sequence. Mol Cell Biol. 1990 Jan; 10(1):371-6. PMID: 2294409; PMCID: PMC360757.
    75. Nielsen DA, Chang TC, Shapiro DJ. A highly sensitive, mixed-phase assay for chloramphenicol acetyltransferase activity in transfected cells. Anal Biochem. 1989 May 15; 179(1):19-23. PMID: 2757194.
      View in: PubMed
    76. Shapiro DJ, Barton MC, McKearin DM, Chang TC, Lew D, Blume J, Nielsen DA, Gould L. Estrogen regulation of gene transcription and mRNA stability. Recent Prog Horm Res. 1989; 45:29-58; discussion 58-64. PMID: 2682843.
      View in: PubMed
    77. Welsh M, Weber T, Wrange O, Nielsen DA, Matthieu M, Steiner DF. Regulation of insulin gene expression by dexamethasone, Ca2+ and a phorbol ester. Biomed Biochim Acta. 1988; 47(4-5):299-303. PMID: 3071361.
      View in: PubMed
    78. Shapiro DJ, Blume JE, Nielsen DA. Regulation of messenger RNA stability in eukaryotic cells. Bioessays. 1987 May; 6(5):221-6. PMID: 3606588.
      View in: PubMed
    79. Steiner DF, Chan SJ, Welsh JM, Nielsen D, Michael J, Tager HS, Rubenstein AH. Models of peptide biosynthesis: the molecular and cellular basis of insulin production. Clin Invest Med. 1986 Nov; 9(4):328-36. PMID: 3542328.
      View in: PubMed
    80. Nielsen DA, Shapiro DJ. Preparation of capped RNA transcripts using T7 RNA polymerase. Nucleic Acids Res. 1986 Jul 25; 14(14):5936. PMID: 3526287; PMCID: PMC311604.
    81. Welsh M, Nielsen DA, MacKrell AJ, Steiner DF. Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. II. Regulation of insulin mRNA stability. J Biol Chem. 1985 Nov 5; 260(25):13590-4. PMID: 3902821.
      View in: PubMed
    82. Nielsen DA, Welsh M, Casadaban MJ, Steiner DF. Control of insulin gene expression in pancreatic beta-cells and in an insulin-producing cell line, RIN-5F cells. I. Effects of glucose and cyclic AMP on the transcription of insulin mRNA. J Biol Chem. 1985 Nov 5; 260(25):13585-9. PMID: 2997172.
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    83. Nielsen DA, Chou J, MacKrell AJ, Casadaban MJ, Steiner DF. Expression of a preproinsulin-beta-galactosidase gene fusion in mammalian cells. Proc Natl Acad Sci U S A. 1983 Sep; 80(17):5198-202. PMID: 6310564; PMCID: PMC384219.
    84. Nielsen DA, Lernmark A, Berelowitz M, Bloom GD, Steiner DF. Sorting of pancreatic islet cell subpopulations by light scattering using a fluorescence-activated cell sorter. Diabetes. 1982 Apr; 31(4 Pt 1):299-306. PMID: 6130019.
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    85. Baekkeskov S, Kanatsuna T, Klareskog L, Nielsen DA, Peterson PA, Rubenstein AH, Steiner DF, Lernmark A. Expression of major histocompatibility antigens on pancreatic islet cells. Proc Natl Acad Sci U S A. 1981 Oct; 78(10):6456-60. PMID: 7031653; PMCID: PMC349058.
    86. Lernmark A, Nielsen DA, Nielsen O, Larsen JK. Light scattering analysis of rat and mouse islet cells in the fluorescence-activated cell sorter. Ups J Med Sci. 1981; 86(2):119-24. PMID: 7034342.
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    87. Steiner DF, Patzelt C, Chan SJ, Quinn PS, Tager HS, Nielsen D, Lernmark A, Noyes BE, Agarwal KL, Gabbay KH, Rubenstein AH. Formation of biologically active peptides. Proc R Soc Lond B Biol Sci. 1980 Oct 29; 210(1178):45-59. PMID: 6107930.
      View in: PubMed
    88. Lernmark A, Nielsen DA, Parman AU, Sehlin J, Steiner DF, Täljedal IB. Cation-activated phosphatase activities in islet cell plasma membrane preparations. Horm Metab Res Suppl. 1980; Suppl 10:55-61. PMID: 6256271.
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    89. Lernmark A, Nielsen DA, Steiner DF. Cation-dependent phosphatase activites in a rat pancreatic islet plasma membrane fraction prepared by one-step gradient centrifugation. J Supramol Struct. 1978; 9(3):327-36. PMID: 34753.
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