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BINOY SHIVANNA

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
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    Collapse awards and honors
    2007Pediatric Resident of the Year, Newark Beth Israel Medical Center, Newark, NJ
    2009 - 2010Fellows Day - Award for Best Poster Presentation of Research, Department of Pediatrics, Baylor College of Medicine, Houston, TX
    2009Young Investigator Award, AAP Section on Perinatal Pediatrics at National Conference, American Academy of Pediatrics
    2009Texas Pediatrics Society Fellow Electronic Poster Contest, Texas Pediatric Society
    2010Arnold J. Rudolph Award for Outstanding Teaching, Patient Care, and Scientific Inquiry, Section of Neonatology, Baylor College of Medicine, Houston, TX
    2011Young Investigator Award, Southern Society of Pediatric Research Regional meeting, Southern Society of Pediatric Research
    2012 - 2015Young Faculty Award, Southern Society of Pediatric Research
    2013John R. Kelsey, Jr. Student Speaker Award, Graduate Student Symposium, Graduate School of Biomedical Sciences, Baylor College of Medicine, Houston, TX
    2015Pediatric Scientific Abstract Award, American Thoracic Society

    Collapse Overview 
    Collapse keywords
    Bronchopulmonary dysplasia, pulmonary hypertension, oxidative stress, inflammation, aryl hydrocarbon receptor, omeprazole, leflunomide, adrenomedullin


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Reynolds CL, Zhang S, Shrestha AK, Barrios R, Shivanna B. Phenotypic assessment of pulmonary hypertension using high-resolution echocardiography is feasible in neonatal mice with experimental bronchopulmonary dysplasia and pulmonary hypertension: a step toward preventing chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2016; 11:1597-605. PMID: 27478373; PMCID: PMC4951055.
    2. Shivanna B, Maity S, Zhang S, Patel A, Jiang W, Wang L, Welty SE, Belmont J, Coarfa C, Moorthy B. Gene Expression Profiling Identifies Cell Proliferation and Inflammation as the Predominant Pathways Regulated by Aryl Hydrocarbon Receptor in Primary Human Fetal Lung Cells Exposed to Hyperoxia. Toxicol Sci. 2016 Jul; 152(1):155-68. PMID: 27103661.
      View in: PubMed
    3. Zhang S, Patel A, Moorthy B, Shivanna B. Omeprazole induces NAD(P)H quinone oxidoreductase 1 via aryl hydrocarbon receptor-independent mechanisms: Role of the transcription factor nuclear factor erythroid 2-related factor 2. Biochem Biophys Res Commun. 2015 Nov 13; 467(2):282-7. PMID: 26441083.
      View in: PubMed
    4. Patel A, Zhang S, Moorthy B, Shivanna B. Omeprazole does not Potentiate Acute Oxygen Toxicity in Fetal Human Pulmonary Microvascular Endothelial Cells Exposed to Hyperoxia. Pharm Anal Acta. 2015 Oct; 6(10). PMID: 26779382.
      View in: PubMed
    5. Patel A, Zhang S, Paramahamsa M, Jiang W, Wang L, Moorthy B, Shivanna B. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor. Drug Metab Dispos. 2015 Dec; 43(12):1966-70. PMID: 26417045.
      View in: PubMed
    6. Shivanna B, Zhang S, Patel A, Jiang W, Wang L, Welty SE, Moorthy B. Omeprazole Attenuates Pulmonary Aryl Hydrocarbon Receptor Activation and Potentiates Hyperoxia-Induced Developmental Lung Injury in Newborn Mice. Toxicol Sci. 2015 Nov; 148(1):276-87. PMID: 26272953.
      View in: PubMed
    7. Zhang S, Patel A, Moorthy B, Shivanna B. Adrenomedullin deficiency potentiates hyperoxic injury in fetal human pulmonary microvascular endothelial cells. Biochem Biophys Res Commun. 2015 Sep 4; 464(4):1048-53. PMID: 26196743.
      View in: PubMed
    8. Zhang S, Patel A, Chu C, Jiang W, Wang L, Welty SE, Moorthy B, Shivanna B. Aryl hydrocarbon receptor is necessary to protect fetal human pulmonary microvascular endothelial cells against hyperoxic injury: Mechanistic roles of antioxidant enzymes and RelB. Toxicol Appl Pharmacol. 2015 Jul 15; 286(2):92-101. PMID: 25831079.
      View in: PubMed
    9. Wang L, Lingappan K, Jiang W, Couroucli XI, Welty SE, Shivanna B, Barrios R, Wang G, Firoze Khan M, Gonzalez FJ, Jackson Roberts L, Moorthy B. Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury. Free Radic Biol Med. 2015 May; 82:147-59. PMID: 25680282; PMCID: PMC4418801.
    10. Lingappan K, Jiang W, Wang L, Wang G, Couroucli XI, Shivanna B, Welty SE, Barrios R, Khan MF, Nebert DW, Roberts LJ, Moorthy B. Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress. Toxicol Sci. 2014 Sep; 141(1):68-77. PMID: 24893714; PMCID: PMC4200035.
    11. Thakur VS, Liang YW, Lingappan K, Jiang W, Wang L, Barrios R, Zhou G, Guntupalli B, Shivanna B, Maturu P, Welty SE, Moorthy B, Couroucli XI. Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicol Lett. 2014 Oct 15; 230(2):322-32. PMID: 24657529; PMCID: PMC4169345.
    12. Sen P, Yang Y, Navarro C, Silva I, Szafranski P, Kolodziejska KE, Dharmadhikari AV, Mostafa H, Kozakewich H, Kearney D, Cahill JB, Whitt M, Bilic M, Margraf L, Charles A, Goldblatt J, Gibson K, Lantz PE, Garvin AJ, Petty J, Kiblawi Z, Zuppan C, McConkie-Rosell A, McDonald MT, Peterson-Carmichael SL, Gaede JT, Shivanna B, Schady D, Friedlich PS, Hays SR, Palafoll IV, Siebers-Renelt U, Bohring A, Finn LS, Siebert JR, Galambos C, Nguyen L, Riley M, Chassaing N, Vigouroux A, Rocha G, Fernandes S, Brumbaugh J, Roberts K, Ho-Ming L, Lo IF, Lam S, Gerychova R, Jezova M, Valaskova I, Fellmann F, Afshar K, Giannoni E, Muhlethaler V, Liang J, Beckmann JS, Lioy J, Deshmukh H, Srinivasan L, Swarr DT, Sloman M, Shaw-Smith C, van Loon RL, Hagman C, Sznajer Y, Barrea C, Galant C, Detaille T, Wambach JA, Cole FS, Hamvas A, Prince LS, Diderich KE, Brooks AS, Verdijk RM, Ravindranathan H, Sugo E, Mowat D, Baker ML, Langston C, Welty S, Stankiewicz P. Novel FOXF1 mutations in sporadic and familial cases of alveolar capillary dysplasia with misaligned pulmonary veins imply a role for its DNA binding domain. Hum Mutat. 2013 Jun; 34(6):801-11. PMID: 23505205; PMCID: PMC3663886.
    13. Shivanna B, Rios D, Rossano J, Fernandes CJ, Pammi M. Vasopressin and its analogues for the treatment of refractory hypotension in neonates. Cochrane Database Syst Rev. 2013; (3):CD009171. PMID: 23543571.
      View in: PubMed
    14. Shivanna B, Zhang W, Jiang W, Welty SE, Couroucli XI, Wang L, Moorthy B. Functional deficiency of aryl hydrocarbon receptor augments oxygen toxicity-induced alveolar simplification in newborn mice. Toxicol Appl Pharmacol. 2013 Mar 15; 267(3):209-17. PMID: 23337360; PMCID: PMC3582791.
    15. Shivanna B, Chu C, Welty SE, Jiang W, Wang L, Couroucli XI, Moorthy B. Omeprazole attenuates hyperoxic injury in H441 cells via the aryl hydrocarbon receptor. Free Radic Biol Med. 2011 Nov 15; 51(10):1910-7. PMID: 21906671; PMCID: PMC3901644.
    16. Shivanna B, Jiang W, Wang L, Couroucli XI, Moorthy B. Omeprazole attenuates hyperoxic lung injury in mice via aryl hydrocarbon receptor activation and is associated with increased expression of cytochrome P4501A enzymes. J Pharmacol Exp Ther. 2011 Oct; 339(1):106-14. PMID: 21768223; PMCID: PMC3186283.
    17. Joshi AA, Bradoo RA, Kadam S, Binoy S, Mondkar J, Kalgutkar A. Tracheal agenesis. Indian J Otolaryngol Head Neck Surg. 2005 Apr; 57(2):141-2. PMID: 23120152; PMCID: PMC3450959.
    18. Kadam S, Binoy S, Kanbur W, Mondkar JA, Fernandez A. Feasibility of kangaroo mother care in Mumbai. Indian J Pediatr. 2005 Jan; 72(1):35-8. PMID: 15684446.
      View in: PubMed
    19. Mohapatra A, Sankaranarayanan K, Kadam SS, Binoy S, Kanbur WA, Mondkar JA. Congenital rickets. J Trop Pediatr. 2003 Apr; 49(2):126-7. PMID: 12729298.
      View in: PubMed
    20. Mohapatra A, Binoy S, Mondkar J . Journal of Neonatology. Placental blood transfusion: An alternate source for transfusion. 2003; (17):45-52.
    21. Mondkar J, Binoy S, Fernandez A . Journal of Neonatology. Pharmacological Principles in the Newborn. 2002; (16):4-10.
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